Annals of Allergy Asthma & Immunology最新文献

{"title":"Mold exposure and rhinitis symptoms among children attending Head Start centers in New York City.","authors":"Jin Feng, Luis Acosta, Maxine Ashby Thompson, Judith S Jacobson, Matthew S Perzanowski","doi":"10.1016/j.anai.2026.01.003","DOIUrl":"10.1016/j.anai.2026.01.003","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145991623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Readers","authors":"","doi":"10.1016/S1081-1206(25)01337-7","DOIUrl":"10.1016/S1081-1206(25)01337-7","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Page A1"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“I wish someone said along the way”: Patient perspectives on penicillin allergy evaluation during pregnancy","authors":"Lulu R. Tsao MD , Angela L. Chang MD , Jennifer Z. Qin MD , Sara L. Ackerman PhD, MPH , Roxanna A. Irani MD, PhD , Iris M. Otani MD","doi":"10.1016/j.anai.2025.09.023","DOIUrl":"10.1016/j.anai.2025.09.023","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Pages 105-107"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of eosinophil-to-lymphocyte ratio combined with computed tomography scores for olfactory recovery in chronic rhinosinusitis with nasal polyps","authors":"Liufeiyan Fan PhD ,&nbsp;Zhong Zheng PhD ,&nbsp;Haofei Bai MD ,&nbsp;Silyu Jing MD ,&nbsp;Chunyang Zhang PhD ,&nbsp;Weijia Du MD ,&nbsp;Yubin Lai MD ,&nbsp;Min Xu MD ,&nbsp;Jian Wang PhD ,&nbsp;Tao Xue PhD ,&nbsp;Fuquan Chen PhD","doi":"10.1016/j.anai.2025.10.009","DOIUrl":"10.1016/j.anai.2025.10.009","url":null,"abstract":"<div><h3>Background</h3><div>Chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating inflammatory disease often complicated by olfactory dysfunction. Despite surgery being a primary treatment, predicting postoperative olfactory recovery remains challenging. Eosinophilic inflammation and sinus computed tomography (CT) characteristics may serve as prognostic markers, yet their combined utility in predicting olfactory dysfunction outcomes is underexplored.</div></div><div><h3>Objective</h3><div>To investigate the predictive effect of eosinophil-to-lymphocyte ratio (ELR) from peripheral blood tests, combined with ethmoid sinus-to-maxillary sinus (E/M) ratio, and ethmoid sinus score minus maxillary sinus score (E-M) on olfactory recovery in patients with CRSwNP.</div></div><div><h3>Methods</h3><div>This single-center, retrospective cohort study was conducted from January 2022 to June 2024. A total of 137 patients with CRSwNP and 52 healthy controls were included. Preoperative and postoperative olfactory functions were assessed using the Sniffin' Sticks test. ELR, E/M ratio, and E-M score were calculated based on blood tests and CT scans. Logistic regression analysis and receiver operating characteristic curve analysis were used to identify and validate predictive factors for olfactory recovery.</div></div><div><h3>Results</h3><div>The median preoperative threshold-discrimination-identification score was 10 (IQR 7-24), improving to 26 (IQR 15-33) at 6 months postoperatively, with a median improvement (change in threshold-discrimination-identification) of 7 (IQR 2-14). ELR, E/M ratio, and E-M score were significantly higher in patients with poor olfactory recovery (all <em>P</em> &lt; .05). Logistic regression analysis revealed that ELR (model 1: odds ratio [OR] = 1.199; model 2: OR = 1.209), E/M ratio (OR = 3.236), and E-M score (OR = 2.179) were independent risk factors for poor olfactory prognosis. Receiver operating characteristic curve analysis revealed that the combined index demonstrated superior predictive performance.</div></div><div><h3>Conclusion</h3><div>A composite model integrating ELR with CT-based E/M ratio or E-M score effectively predicts olfactory recovery in patients with CRSwNP. These accessible biomarkers aid in stratifying patients for personalized treatment and postoperative monitoring.</div></div><div><h3>Trial Registration</h3><div>ChiCTR2100047644.</div></div>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Pages 92-100.e3"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urgent need for collaboration in the allergy workforce for infants and toddlers","authors":"Karen Rance DNP, CPNP ,&nbsp;Amanda Michaud DMSc, PA-C, AE-C ,&nbsp;Michael Pistiner MD, MMSc","doi":"10.1016/j.anai.2025.09.025","DOIUrl":"10.1016/j.anai.2025.09.025","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Pages 9-11"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food protein-induced enterocolitis syndrome (FPIES)","authors":"Fallon Schultz MSW, LCSW, CAM ,&nbsp;Landon J. Schultz ,&nbsp;Anna Nowak-Wegrzyn MD, PhD","doi":"10.1016/j.anai.2025.10.032","DOIUrl":"10.1016/j.anai.2025.10.032","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Pages 1-2"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the network: Understanding allergy and immunology patient perception and behavior on social media","authors":"Courtney Cotter DO ,&nbsp;Christopher Brooks MD ,&nbsp;David Stukus MD ,&nbsp;Farah Khan MD","doi":"10.1016/j.anai.2025.09.031","DOIUrl":"10.1016/j.anai.2025.09.031","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Pages 107-108"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial impact and multidisciplinary care of food protein-induced enterocolitis syndrome","authors":"Ianthe R.M. Schepel BMBCh, MPhil, MS ,&nbsp;Mia Vaida BS ,&nbsp;Jennifer S. LeBovidge PhD ,&nbsp;Wendy Elverson RD, LDN ,&nbsp;Fallon Schultz MSW, LCSW, CAM ,&nbsp;Erin P. Syverson MD ,&nbsp;Elena Crestani MD, MS ,&nbsp;Lisa M. Bartnikas MD","doi":"10.1016/j.anai.2025.09.029","DOIUrl":"10.1016/j.anai.2025.09.029","url":null,"abstract":"<div><div>Food protein-induced enterocolitis syndrome (FPIES) has a significant impact on patients and caregivers across multiple psychosocial domains. This paper outlines what is known about key contributors to the psychosocial burden of FPIES, questions that clinicians can ask to better understand this burden, and indications for referral to multidisciplinary members of FPIES care teams to manage specific psychosocial concerns. The authors propose concrete interventions to address major unmet needs in FPIES through education, advocacy, clinical care, and research. There is great scope for further research to characterize the unique psychosocial challenges that FPIES poses, which should include development and validation of FPIES-specific measures for psychosocial functioning to help guide management of individual patients, develop better resources for support, and study the psychosocial impact of interventions. Alleviating the psychosocial burden of FPIES for patients and families ultimately depends on promoting evidence-based and integrated multidisciplinary care of FPIES. Efforts should focus on deepening scientific understanding, enhancing diagnostic and management tools, and ensuring that evolving clinical guidelines meet the needs of both pediatric and adult patients worldwide.</div></div>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Pages 33-40"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of clinical rotation on resident competency in allergy and clinical immunology","authors":"Michael Aw MD ,&nbsp;Fatemah AlYaqout MD, FRCPC ,&nbsp;Natacha Tardio MD, FRCPC ,&nbsp;Abeer Feteih MD, FRCPC ,&nbsp;Michael Nathan Fein MD, MSc, FRCPC","doi":"10.1016/j.anai.2025.10.011","DOIUrl":"10.1016/j.anai.2025.10.011","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Pages 101-103"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airway overlap syndromes with asthma","authors":"Carlos Amado MD ,&nbsp;Daniel Lopez-Padilla MD ,&nbsp;Raúl Méndez MD ,&nbsp;Miguel Ángel Martínez-García MD, PhD","doi":"10.1016/j.anai.2025.09.012","DOIUrl":"10.1016/j.anai.2025.09.012","url":null,"abstract":"<div><div>The airways, defined as the segment of the respiratory system extending from the pharynx to the alveoli, represent a crucial site for various inflammatory airway diseases. Among the most common are asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and obstructive sleep apnea (OSA). Owing to their high individual prevalence, it is not unusual for a single patient to have 2 or more of these conditions simultaneously. Beyond this epidemiologic coincidence, several pathophysiologic links, despite notable differences among the diseases, have been identified. These connections influence not only the mutual prevalence of the disorders but also their clinical management and prognosis, frequently in a bidirectional manner. This constellation of interactions has been termed “overlap syndromes.” Overlap syndromes involving asthma are especially frequent, including asthma-COPD overlap syndrome, asthma-OSA overlap syndrome, and asthma-bronchiectasis overlap syndrome. These syndromes often exhibit bidirectional relationships. Asthma, for instance, may aggravate COPD symptoms, prompting modifications in its treatment; it may also worsen preexisting OSA through increased pharynx collapsability, the use of inhaled corticosteroids, or contribute to more frequent bronchiectasis exacerbations. Conversely, the presence of COPD can hinder adequate asthma control, bronchiectasis may enhance the inflammatory burden and exacerbate asthma, and OSA can induce harmful nocturnal oxygen desaturations that impair asthma outcomes. These complex and dynamic interactions underscore the importance of recognizing overlap syndromes in clinical practice. An integrated, individualized approach that considers the coexistence of multiple airway diseases is essential for optimizing diagnosis, therapeutic interventions, and long-term prognosis in affected patients.</div></div>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"136 1","pages":"Pages 41-51"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}