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An Iron-Less Ironman. 无铁铁人三项赛
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-11-08 DOI: 10.1016/j.amjmed.2024.10.022
Musa Kiyani, Ibrahim Hanif, Denise Tan
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引用次数: 0
Are Blood-based Cancer Screening Tests Ready for Primetime? 基于血液的癌症筛查测试是否已准备就绪？
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-11-08 DOI: 10.1016/j.amjmed.2024.10.023
Vinay Prasad, Alyson Haslam, Timothee Olivier
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引用次数: 0
Diabetic Cardiomyopathy: What Clinicians Should Know. 糖尿病心肌病：临床医生须知。
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-11-04 DOI: 10.1016/j.amjmed.2024.10.026
Hannah Smati, Yusuf Kamran Qadeer, Mario Rodriguez, Errol Moras, Gregg C Fonarow, Scott D Isaacs, Thomas H Marwick, Chayakrit Krittanawong

Diabetes has classically been associated with atherosclerotic cardiovascular disease. However, heart failure is now increasingly recognized as a prevalent and often first cardiovascular complication among patients with diabetes. Investigation of this epidemiological relationship has led to recognition of diabetic cardiomyopathy, or structural heart disease that develops in patients with diabetes and may lead to progressive heart failure independently of coronary artery disease or conventional cardiovascular risk factors such as hypertension. Despite increased awareness, clinical management of this common cardiovascular complication remains challenging, with no consensus on its diagnosis or treatment. The lack of specific therapy has been recognized as an unmet clinical need. In this review, we summarize current understanding of the hallmark metabolic and structural changes of diabetic cardiomyopathy, appraise current tools for diagnosis and staging among patients, and describe the emerging but still preclinical data on therapeutic options.

糖尿病通常与动脉粥样硬化性心血管疾病相关。然而，现在越来越多的人认识到，心力衰竭是糖尿病患者普遍存在的一种心血管并发症，而且往往是第一种心血管并发症。通过对这一流行病学关系的研究，人们认识到糖尿病心肌病，即糖尿病患者发生结构性心脏病，并可能导致进行性心力衰竭，而与冠状动脉疾病或高血压等传统心血管风险因素无关。尽管人们对这一常见心血管并发症的认识有所提高，但其临床治疗仍然充满挑战，在诊断和治疗方面尚未达成共识。缺乏特异性疗法已被认为是尚未满足的临床需求。在这篇综述中，我们总结了目前对糖尿病心肌病标志性代谢和结构变化的认识，评估了目前对患者进行诊断和分期的工具，并描述了正在出现但仍处于临床前阶段的治疗方案数据。
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引用次数: 0
Getting to the Heart of the Matter-A Rare Case of Treponema pallidum Endocarditis. 直击问题核心--苍白链球菌心内膜炎的罕见病例。
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-11-04 DOI: 10.1016/j.amjmed.2024.10.031
Tyler Brehm, Cameron A Brown, Neda Zarrin-Khameh, Christopher B Sylvester, Ravi Ghanta, Jill Weatherhead, Eva H Clark
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引用次数: 0
Syphilitic Paronychia. 梅毒性脓疱疮
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-11-04 DOI: 10.1016/j.amjmed.2024.10.018
Shintaro Kakimoto, Yukinori Harada, Taro Shimizu
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引用次数: 0
The Reply 答复是
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-10-24 DOI: 10.1016/j.amjmed.2024.06.035
Yoshinori Tateishi MD
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引用次数: 0
Statin Therapy, Incident Dementia and All-Cause Mortality in Older Adults with Special Reference to Kidney Function 他汀类药物治疗、老年痴呆症和全因死亡率，特别是肾功能。
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-10-24 DOI: 10.1016/j.amjmed.2024.05.006
Tomoyuki Kawada MD
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引用次数: 0
The Reply 答复是
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-10-24 DOI: 10.1016/j.amjmed.2024.06.020
Adam Gross MD , Mandeep S. Sidhu MD, MBA , Roy O. Mathew MD
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引用次数: 0
The Reply 答复是
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-10-24 DOI: 10.1016/j.amjmed.2024.07.035
Ami Schattner MD
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引用次数: 0
Cardiovascular Physical Examination in Internal Medicine Residents: Pause for Concern 内科住院医生的心血管体检：暂停关注。
IF 2.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
American Journal of Medicine
Pub Date : 2024-10-24 DOI: 10.1016/j.amjmed.2024.06.032
Jacob Draves MA , Halil Tekiner PhD , Steven H. Yale MD , Eileen S. Yale MD
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引用次数: 0
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