Pub Date : 2024-04-01DOI: 10.1097/01.ogx.0001016664.40824.26
Tara T M Lee, Corinne Collett, Simon Bergford, S. Hartnell, Eleanor M Scott, Robert Lindsay, Katharine F. Hunt, D. R. McCance, Katharine Barnard-Kelly, David Rankin, Julia Lawton, Rebecca M. Reynolds, Emma Flanagan, M. Hammond, Lee Shepstone, M. Wilinska, J. Sibayan, C. Kollman, Roy Beck, R. Hovorka, Helen R Murphy
(Abstracted from N Engl J Med 2023;389:1566–1578 Hyperglycemia during pregnancy is an important risk factor for complications, such as preterm birth, large birth weight, and admission to the intensive care unit. Those at highest risk already have glycated hemoglobin above target levels at the start of pregnancy.
{"title":"Automated Insulin Delivery in Women With Pregnancy Complicated by Type 1 Diabetes","authors":"Tara T M Lee, Corinne Collett, Simon Bergford, S. Hartnell, Eleanor M Scott, Robert Lindsay, Katharine F. Hunt, D. R. McCance, Katharine Barnard-Kelly, David Rankin, Julia Lawton, Rebecca M. Reynolds, Emma Flanagan, M. Hammond, Lee Shepstone, M. Wilinska, J. Sibayan, C. Kollman, Roy Beck, R. Hovorka, Helen R Murphy","doi":"10.1097/01.ogx.0001016664.40824.26","DOIUrl":"https://doi.org/10.1097/01.ogx.0001016664.40824.26","url":null,"abstract":"(Abstracted from N Engl J Med 2023;389:1566–1578\u0000 Hyperglycemia during pregnancy is an important risk factor for complications, such as preterm birth, large birth weight, and admission to the intensive care unit. Those at highest risk already have glycated hemoglobin above target levels at the start of pregnancy.","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"144 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140787076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
(Abstracted from Obstet Gynecol Sci 2023;66:572–583 Polycystic ovary syndrome (PCOS) is frequently treated using low-dose hormonal pills with ethinylestradiol (EE) 35 μg combined with progestins for cycle control. Use of these combined oral contraceptives has been associated with metabolic syndrome, dyslipidemia, and a risk of cardiovascular events for women with metabolic disorders.
{"title":"Randomized Control Trial to Compare Effects of Ultra-Low Dose (Ethinylestradiol 20 μg or 15 μg) With Low Dose (Ethinylestradiol 30 μg) Hormonal Pills on Lipid Discordance in Non-Obese PCOS Women","authors":"Subhankar Dasgupta, Joyeeta Mondal, Barnali Goswami, Jija Dasgupta","doi":"10.1097/ogx.0000000000001264","DOIUrl":"https://doi.org/10.1097/ogx.0000000000001264","url":null,"abstract":"(Abstracted from Obstet Gynecol Sci 2023;66:572–583\u0000 Polycystic ovary syndrome (PCOS) is frequently treated using low-dose hormonal pills with ethinylestradiol (EE) 35 μg combined with progestins for cycle control. Use of these combined oral contraceptives has been associated with metabolic syndrome, dyslipidemia, and a risk of cardiovascular events for women with metabolic disorders.","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"133 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1097/01.ogx.0001016660.67661.8d
Alexandria C. Kraus, Alexander M Saucedo, John J Byrne, Lina F. Chalak, Jessica E. Pruszynski, Catherine Y. Spong
(Abstracted from Am J Obstet Gynecol 2023;229:439.e1–439.e11 It is common for fetal oxygenation and pH to decline during labor. However, severe oxygen deprivation can cause fetuses to develop metabolic acidemia, a risk factor for moderate to severe neonatal encephalopathy that can progress to cerebral palsy.
{"title":"A Comparison of Criteria for Defining Metabolic Acidemia in Live-Born Neonates and Its Effect on Predicting Serious Adverse Neonatal Outcomes","authors":"Alexandria C. Kraus, Alexander M Saucedo, John J Byrne, Lina F. Chalak, Jessica E. Pruszynski, Catherine Y. Spong","doi":"10.1097/01.ogx.0001016660.67661.8d","DOIUrl":"https://doi.org/10.1097/01.ogx.0001016660.67661.8d","url":null,"abstract":"(Abstracted from Am J Obstet Gynecol 2023;229:439.e1–439.e11\u0000 It is common for fetal oxygenation and pH to decline during labor. However, severe oxygen deprivation can cause fetuses to develop metabolic acidemia, a risk factor for moderate to severe neonatal encephalopathy that can progress to cerebral palsy.","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"314 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1097/ogx.0000000000001268
K. Lannering, Kalliopi Kazamia, Gunnar Bergman, Ingegerd Östman-Smith, P. Liuba, J. Dahlqvist, Anders Elfvin, Mats Mellander
(Abstracted from Pediatrics 2023;152:e2023061949 Critical congenital heart defects (CCHDs) affect between 1 and 3 of every 1000 live-born infants and require intervention in the short term after birth. Early identification of affected infants contributes to significantly to better outcomes in both the short- and long-term.
{"title":"Screening for Critical Congenital Heart Defects in Sweden","authors":"K. Lannering, Kalliopi Kazamia, Gunnar Bergman, Ingegerd Östman-Smith, P. Liuba, J. Dahlqvist, Anders Elfvin, Mats Mellander","doi":"10.1097/ogx.0000000000001268","DOIUrl":"https://doi.org/10.1097/ogx.0000000000001268","url":null,"abstract":"(Abstracted from Pediatrics 2023;152:e2023061949\u0000 Critical congenital heart defects (CCHDs) affect between 1 and 3 of every 1000 live-born infants and require intervention in the short term after birth. Early identification of affected infants contributes to significantly to better outcomes in both the short- and long-term.","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"375 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140780984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1097/ogx.0000000000001266
Amber A A Ten Buuren, Tessa B. Poolman, Lauren M. Bullens, N. van Hanegem, Marlies Y. Bongers, Wenche M. Klerkx, Anne Timmermans, N. P. A. Zuithoff, Anneke Kwee
(Abstracted from BJOG. 2024;131:684–689 The World Health Organization emphasizes that the climate crisis is the single biggest health threat facing humanity, and more than 200 medical journals have called on world leaders to take more and faster action against climate change. Despite this, hospitals have increasingly relied on disposable instruments such as plastic specula, which are incinerated after a single use.
{"title":"Patient Preferences for Disposable and Reusable Vaginal Specula and Their Willingness to Compromise in the Era of Climate Change: A Cross-Sectional Study","authors":"Amber A A Ten Buuren, Tessa B. Poolman, Lauren M. Bullens, N. van Hanegem, Marlies Y. Bongers, Wenche M. Klerkx, Anne Timmermans, N. P. A. Zuithoff, Anneke Kwee","doi":"10.1097/ogx.0000000000001266","DOIUrl":"https://doi.org/10.1097/ogx.0000000000001266","url":null,"abstract":"(Abstracted from BJOG. 2024;131:684–689\u0000 The World Health Organization emphasizes that the climate crisis is the single biggest health threat facing humanity, and more than 200 medical journals have called on world leaders to take more and faster action against climate change. Despite this, hospitals have increasingly relied on disposable instruments such as plastic specula, which are incinerated after a single use.","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"92 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140788613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1097/01.ogx.0001016700.92425.05
N. Costa-Borges, Santiago Munne, Eduard Albó, Sergio Mas, Carolina Castello, Guillem Giralt, Zhuo Lu, Charles Chau, M. Acacio, E. Mestres, Queralt Matia, L. Marquès, Mariona Rius, Carmen Marquez, I. Vanrell, Aïda Pujol, D. Mataró, Michelle Seth-Smith, L. Mollinedo, Gloria Calderon, John Zhang
(Abstracted from Reprod Biomed Online 2023;47:103237 Intracytoplasmic sperm injection (ICSI) is a common procedure used in approximately 70% of in vitro fertilization (IVF) cycles. The procedure involves using glass micropipettes to penetrate the oolemma and injection of sperm into the oocyte.
{"title":"First Babies Conceived With Automated Intracytoplasmic Sperm Injection","authors":"N. Costa-Borges, Santiago Munne, Eduard Albó, Sergio Mas, Carolina Castello, Guillem Giralt, Zhuo Lu, Charles Chau, M. Acacio, E. Mestres, Queralt Matia, L. Marquès, Mariona Rius, Carmen Marquez, I. Vanrell, Aïda Pujol, D. Mataró, Michelle Seth-Smith, L. Mollinedo, Gloria Calderon, John Zhang","doi":"10.1097/01.ogx.0001016700.92425.05","DOIUrl":"https://doi.org/10.1097/01.ogx.0001016700.92425.05","url":null,"abstract":"(Abstracted from Reprod Biomed Online 2023;47:103237\u0000 Intracytoplasmic sperm injection (ICSI) is a common procedure used in approximately 70% of in vitro fertilization (IVF) cycles. The procedure involves using glass micropipettes to penetrate the oolemma and injection of sperm into the oocyte.","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"39 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140775325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1097/01.ogx.0001016688.86364.3f
M. D. Creinin, Alicyoy Angulo, Enrico Colli, David F. Archer
(Abstracted from Contraception 2023;128:1–7 There is a lack of data regarding the safety and efficacy of oral contraceptives in people with a body mass index (BMI) over 35. Drospirenone 4 mg is a new progestogen-only contraceptive pill that is taken in a 24 + 4 pattern, with 24 hormonal and 4 placebo pills.
{"title":"The Efficacy, Safety, and Tolerability of an Estrogen-Free Oral Contraceptive Drospirenone 4 mg (24/4-Day Regimen) in Obese Users","authors":"M. D. Creinin, Alicyoy Angulo, Enrico Colli, David F. Archer","doi":"10.1097/01.ogx.0001016688.86364.3f","DOIUrl":"https://doi.org/10.1097/01.ogx.0001016688.86364.3f","url":null,"abstract":"(Abstracted from Contraception 2023;128:1–7\u0000 There is a lack of data regarding the safety and efficacy of oral contraceptives in people with a body mass index (BMI) over 35. Drospirenone 4 mg is a new progestogen-only contraceptive pill that is taken in a 24 + 4 pattern, with 24 hormonal and 4 placebo pills.","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"75 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140778169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1097/01.ogx.0001016696.16905.e0
M. Lumish, Elise C. Kohn, William P. Tew
(Abstracted from Cancer 2024;130:837–845 Although novel systemic therapies have prolonged survival in ovarian cancer, it remains the fifth leading cause of cancer-related death in women. In 2022, data showing an overall survival (OS) benefit from poly(ADP-ribose) polymerase (PARP) inhibitor (PARPi) were published after a 7-year follow-up period.
{"title":"Top Advances of the Year: Ovarian Cancer","authors":"M. Lumish, Elise C. Kohn, William P. Tew","doi":"10.1097/01.ogx.0001016696.16905.e0","DOIUrl":"https://doi.org/10.1097/01.ogx.0001016696.16905.e0","url":null,"abstract":"(Abstracted from Cancer 2024;130:837–845\u0000 Although novel systemic therapies have prolonged survival in ovarian cancer, it remains the fifth leading cause of cancer-related death in women. In 2022, data showing an overall survival (OS) benefit from poly(ADP-ribose) polymerase (PARP) inhibitor (PARPi) were published after a 7-year follow-up period.","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"509 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140773322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1097/01.ogx.0001010420.53414.ec
M. F. Paz y Miño, M. Pauta, E. Meler, I. Matas, E. Mazarico, A. Camacho, M. Segura, F. Figueras, A. Borrell
Small for gestational age (SGA) newborns are generally defined as those with a birth weight below the 10th percentile. Fetuses diagnosed with fetal growth restriction (FGR) are usually evaluated to determine if there is a pathological cause and thus a higher risk for adverse outcomes due to being small. Often when this diagnosis is made early in the third trimester, chromosomal microarray analysis is recommended to detect genetic disease. This study was designed to determine the frequency of monogenic disorders in term infants with severely low birth weight but normal Doppler results, as well as to estimate the frequency of neurodevelopmental impairment when a genetic etiology was ruled out. Inclusion criteria for this study were singleton pregnancy; term delivery; birth weight more than 2.5 SDs below the mean; normal Doppler studies of the umbilical artery, fetal middle cerebral artery, cerebroplacental ratio, and uterine artery; no maternal hypertensive disease; and no prenatal fetal structural or identified genetic anomalies or fetal infection. Exclusion criteria included incomplete data. Exome sequencing was completed using saliva sampling and blood sampling, and standard neurodevelopmental assessment techniques were used for children 2 to 3.5 and 6 to 8 years old. Children aged between 3.5 and 6 years were not included because of lack of standardized neurodevelopmental testing. A total of 63 families were contacted, and 7 (11%) reported that a genetic disorder had been diagnosed after birth. In addition, 18 individuals without a known genetic disorder who met all the criteria underwent exome sequencing and neurodevelopmental testing. Of the 7 who reported a postnatally diagnosed genetic syndrome, 5 were Mendelian monogenetic and 2 were epigenetic, including Cockayne syndrome; short stature, microcephaly, and endocrine dysfunction syndrome; Renpenning syndrome; Noonan syndrome; Russell-Silver syndrome; and Prader-Willi syndrome. Median birth weight among the children with genetic disorders was not different from children without. Exome sequencing was normal in the 18 children who were tested and who had not been previously diagnosed with a genetic syndrome. None of the children showed less than average neurodevelopment on overall assessment in the lower age group. In the higher age group, 2 children were classified as having low IQ, with one borderline and one extremely low, with low scores in all other domains as well. In addition, 6 individuals showed a low score in at least 1 of the 5 domains, with the largest deviations showing in the domains of verbal comprehension and working memory. Clinicians should be aware of the potential outcomes of FGR even when other complications are not present. Counseling about genetic analysis prenatally or within a short postnatal timeframe could save a lot of time and effort in evaluating children later. In addition, children should be carefully assessed in later childhood for neurodevelopmental diff
{"title":"Postnatal Genetic and Neurodevelopmental Assessment in Infants Born at Term With Severely Low Birth Weight of Non-placental Origin","authors":"M. F. Paz y Miño, M. Pauta, E. Meler, I. Matas, E. Mazarico, A. Camacho, M. Segura, F. Figueras, A. Borrell","doi":"10.1097/01.ogx.0001010420.53414.ec","DOIUrl":"https://doi.org/10.1097/01.ogx.0001010420.53414.ec","url":null,"abstract":"\u0000 Small for gestational age (SGA) newborns are generally defined as those with a birth weight below the 10th percentile. Fetuses diagnosed with fetal growth restriction (FGR) are usually evaluated to determine if there is a pathological cause and thus a higher risk for adverse outcomes due to being small. Often when this diagnosis is made early in the third trimester, chromosomal microarray analysis is recommended to detect genetic disease. This study was designed to determine the frequency of monogenic disorders in term infants with severely low birth weight but normal Doppler results, as well as to estimate the frequency of neurodevelopmental impairment when a genetic etiology was ruled out.\u0000 Inclusion criteria for this study were singleton pregnancy; term delivery; birth weight more than 2.5 SDs below the mean; normal Doppler studies of the umbilical artery, fetal middle cerebral artery, cerebroplacental ratio, and uterine artery; no maternal hypertensive disease; and no prenatal fetal structural or identified genetic anomalies or fetal infection. Exclusion criteria included incomplete data. Exome sequencing was completed using saliva sampling and blood sampling, and standard neurodevelopmental assessment techniques were used for children 2 to 3.5 and 6 to 8 years old. Children aged between 3.5 and 6 years were not included because of lack of standardized neurodevelopmental testing.\u0000 A total of 63 families were contacted, and 7 (11%) reported that a genetic disorder had been diagnosed after birth. In addition, 18 individuals without a known genetic disorder who met all the criteria underwent exome sequencing and neurodevelopmental testing. Of the 7 who reported a postnatally diagnosed genetic syndrome, 5 were Mendelian monogenetic and 2 were epigenetic, including Cockayne syndrome; short stature, microcephaly, and endocrine dysfunction syndrome; Renpenning syndrome; Noonan syndrome; Russell-Silver syndrome; and Prader-Willi syndrome. Median birth weight among the children with genetic disorders was not different from children without. Exome sequencing was normal in the 18 children who were tested and who had not been previously diagnosed with a genetic syndrome.\u0000 None of the children showed less than average neurodevelopment on overall assessment in the lower age group. In the higher age group, 2 children were classified as having low IQ, with one borderline and one extremely low, with low scores in all other domains as well. In addition, 6 individuals showed a low score in at least 1 of the 5 domains, with the largest deviations showing in the domains of verbal comprehension and working memory.\u0000 Clinicians should be aware of the potential outcomes of FGR even when other complications are not present. Counseling about genetic analysis prenatally or within a short postnatal timeframe could save a lot of time and effort in evaluating children later. In addition, children should be carefully assessed in later childhood for neurodevelopmental diff","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"24 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1097/ogx.0000000000001256
Miranda L. Davies-Tuck, Mary-Ann Davey, Ryan L. Hodges, Euan M. Wallace
Women of South Asian background are known to have higher rates of stillbirth than women in other high-income countries, such as Australia or the United Kingdom. To reduce the rate of stillbirth, leading societies recommend antenatal fetal monitoring or induction of labor (IOL) at 41 weeks of gestation regardless of race/ethnicity. However, at 41 weeks' gestation, the risk of stillbirth for South Asian–born women is already up to 5 times higher than for Australian-born women. Initially, the UK National Institution for Health and Care Excellence recommended that all South Asian women undergo IOL earlier, at 39 weeks of gestation. However, this recommendation was criticized as being racist, and perpetuating the myth that race plays a factor in poor outcomes, so it was amended to state that South Asian–born women might benefit from additional monitoring and support. Still, there is no evidence to support this guidance. In July 2017, the State of Victoria in Australia implemented a new clinical guideline to provide South Asian women with biweekly cardiotocography and amniotic fluid measurement at 39 weeks of gestation. The aim of this study was to assess the impact of the new clinical guideline on the rates of stillbirth and select pregnancy outcomes for South Asian women. This was a cohort study that included women with singleton pregnancies who gave birth at term or beyond at a university- affiliated teaching health service located in 3 metropolitan areas in Australia from January 1, 2016, to December 31, 2020. Women were classified as South Asian born if they self-identified as being from Afghanistan, Bangladesh, Bhutan, India, Iran, the Maldives, Nepal, Pakistan, or Sri Lanka. The timeframe between January 1, 2016, and June 30, 2017, represented the period before the change in practice for fetal monitoring for South Asian women; the timeframe between July 1, 2017, and December 31, 2020, represented the period after. Although the new practice was applied to South Asian–born women in the second timeframe, fetal monitoring at 41 weeks was applied to all other women. The primary outcome was stillbirth at the onset of or during labor at 37 weeks and 39 weeks of gestation. The secondary outcomes included neonatal death at <7 days, admission to the special care nursery or neonatal intensive care, Apgar score <7 at 5 minutes, infant birthweight, gestation of birth, IOL, and mode of birth. A total of 3506 South Asian women gave birth before the change in practice, whereas 8532 gave birth postimplementation. The rate of stillbirth at 37 weeks' gestation for South Asian–born women was 2.3 per 1000 births—a 2.6-fold higher rate than for other women (0.9 per 1000 births; P = 0.06). After the change in practice, the rate of stillbirth fell by 64% for South Asian–born women (95% confidence interval, 87%–2%; P = 0.047). The association was stronger when the results were restricted to births after 39 weeks of gestation. Also, after the change in practice, redu
{"title":"Fetal Surveillance From 39 Weeks’ Gestation to Reduce Stillbirth in South Asian–Born Women","authors":"Miranda L. Davies-Tuck, Mary-Ann Davey, Ryan L. Hodges, Euan M. Wallace","doi":"10.1097/ogx.0000000000001256","DOIUrl":"https://doi.org/10.1097/ogx.0000000000001256","url":null,"abstract":"\u0000 Women of South Asian background are known to have higher rates of stillbirth than women in other high-income countries, such as Australia or the United Kingdom. To reduce the rate of stillbirth, leading societies recommend antenatal fetal monitoring or induction of labor (IOL) at 41 weeks of gestation regardless of race/ethnicity. However, at 41 weeks' gestation, the risk of stillbirth for South Asian–born women is already up to 5 times higher than for Australian-born women. Initially, the UK National Institution for Health and Care Excellence recommended that all South Asian women undergo IOL earlier, at 39 weeks of gestation. However, this recommendation was criticized as being racist, and perpetuating the myth that race plays a factor in poor outcomes, so it was amended to state that South Asian–born women might benefit from additional monitoring and support. Still, there is no evidence to support this guidance. In July 2017, the State of Victoria in Australia implemented a new clinical guideline to provide South Asian women with biweekly cardiotocography and amniotic fluid measurement at 39 weeks of gestation. The aim of this study was to assess the impact of the new clinical guideline on the rates of stillbirth and select pregnancy outcomes for South Asian women.\u0000 This was a cohort study that included women with singleton pregnancies who gave birth at term or beyond at a university- affiliated teaching health service located in 3 metropolitan areas in Australia from January 1, 2016, to December 31, 2020. Women were classified as South Asian born if they self-identified as being from Afghanistan, Bangladesh, Bhutan, India, Iran, the Maldives, Nepal, Pakistan, or Sri Lanka. The timeframe between January 1, 2016, and June 30, 2017, represented the period before the change in practice for fetal monitoring for South Asian women; the timeframe between July 1, 2017, and December 31, 2020, represented the period after. Although the new practice was applied to South Asian–born women in the second timeframe, fetal monitoring at 41 weeks was applied to all other women. The primary outcome was stillbirth at the onset of or during labor at 37 weeks and 39 weeks of gestation. The secondary outcomes included neonatal death at <7 days, admission to the special care nursery or neonatal intensive care, Apgar score <7 at 5 minutes, infant birthweight, gestation of birth, IOL, and mode of birth.\u0000 A total of 3506 South Asian women gave birth before the change in practice, whereas 8532 gave birth postimplementation. The rate of stillbirth at 37 weeks' gestation for South Asian–born women was 2.3 per 1000 births—a 2.6-fold higher rate than for other women (0.9 per 1000 births; P = 0.06). After the change in practice, the rate of stillbirth fell by 64% for South Asian–born women (95% confidence interval, 87%–2%; P = 0.047). The association was stronger when the results were restricted to births after 39 weeks of gestation. Also, after the change in practice, redu","PeriodicalId":509854,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"1 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140280220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}