Pub Date : 2024-04-15DOI: 10.36347/sjmcr.2024.v12i04.018
B. Raouf, A. Hamdaoui, I. Adali, F. Manoudi
Human immunodeficiency virus (HIV) infection today affects all countries, particularly those in sub-Saharan Africa. objective of this on the one hand to evaluate the nature of psychiatric disorders in patients with HIV and on the other to detect possible predictive factors for the occurrence of these disorders. And compare it with our patient with HIV/AIDS receiving combined antiretroviral therapy and assessment of mood, sleep measurements, health-related quality of life.
今天，人体免疫缺陷病毒（HIV）感染影响着所有国家，尤其是撒哈拉以南非洲国家。一方面，这项研究的目的是评估 HIV 患者精神障碍的性质，另一方面是检测这些障碍发生的可能预测因素。并将其与接受联合抗逆转录病毒疗法和情绪评估、睡眠测量、与健康有关的生活质量的艾滋病毒/艾滋病患者进行比较。
{"title":"Psychiatric Disorders in an HIV-Infected Patient (About a Case)","authors":"B. Raouf, A. Hamdaoui, I. Adali, F. Manoudi","doi":"10.36347/sjmcr.2024.v12i04.018","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.018","url":null,"abstract":"Human immunodeficiency virus (HIV) infection today affects all countries, particularly those in sub-Saharan Africa. objective of this on the one hand to evaluate the nature of psychiatric disorders in patients with HIV and on the other to detect possible predictive factors for the occurrence of these disorders. And compare it with our patient with HIV/AIDS receiving combined antiretroviral therapy and assessment of mood, sleep measurements, health-related quality of life.","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140703293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-15DOI: 10.36347/sjmcr.2024.v12i04.016
H. Arabi, Hafida Bara, A. Mougui, I. E. Bouchti
Tabetic arthropathy is a rare complication of neurosyphilis. It has currently become rare due to the decreased frequency of syphilis and early treatment. We report a case of tabetic arthropathy with multiple localizations. The patient is a 67-year-old individual with no particular medical history. He was hospitalized for painless deformities of both knees and the right elbow, which had been progressing for 25 years, accompanied by the sudden onset of swelling in the left knee, progressing with remission. Later, he developed similar swelling in the right knee and elbow. Subsequently, he experienced progressive and painless instability in both knees, resulting in total functional disability. Standard X-rays of the right elbow, both knees, and the left hand revealed significant joint destruction. Given the discrepancy between the extent of radiological destruction and the painlessness of the affected joint arthropathy, the diagnosis of neurogenic arthropathy was considered. Serology for syphilis was positive (TPHA + and VDRL -) in both blood and cerebrospinal fluid. The diagnosis of polyarticular tabetic arthropathy was confirmed. The patient was treated with a third-generation cephalosporin at a dose of 2g per day intravenously for 21 days. This is a rare case of late-diagnosed multifocal tabetic arthropathy with a catastrophic outcome.
{"title":"Tabetic Arthropathy: A Historical Multiple Localization","authors":"H. Arabi, Hafida Bara, A. Mougui, I. E. Bouchti","doi":"10.36347/sjmcr.2024.v12i04.016","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.016","url":null,"abstract":"Tabetic arthropathy is a rare complication of neurosyphilis. It has currently become rare due to the decreased frequency of syphilis and early treatment. We report a case of tabetic arthropathy with multiple localizations. The patient is a 67-year-old individual with no particular medical history. He was hospitalized for painless deformities of both knees and the right elbow, which had been progressing for 25 years, accompanied by the sudden onset of swelling in the left knee, progressing with remission. Later, he developed similar swelling in the right knee and elbow. Subsequently, he experienced progressive and painless instability in both knees, resulting in total functional disability. Standard X-rays of the right elbow, both knees, and the left hand revealed significant joint destruction. Given the discrepancy between the extent of radiological destruction and the painlessness of the affected joint arthropathy, the diagnosis of neurogenic arthropathy was considered. Serology for syphilis was positive (TPHA + and VDRL -) in both blood and cerebrospinal fluid. The diagnosis of polyarticular tabetic arthropathy was confirmed. The patient was treated with a third-generation cephalosporin at a dose of 2g per day intravenously for 21 days. This is a rare case of late-diagnosed multifocal tabetic arthropathy with a catastrophic outcome.","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140701892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-13DOI: 10.36347/sjmcr.2024.v12i04.013
Manal Bouggar, H. Brarou, Z. Chaibi, Y. Mouzari, Abdelbare Oubaaz
Scleromalacia perforans SP is a rare ocular manifestation of rheumatoid arthritis which can potentially lead to blindness and is a late consequence in the course of the disease; in deed it is most common in elderly female with long-term rheumatoid arthritis, but it was also observed with other systemic diseases. It presents as a blackish blue hue visible through a thin sclera. scleral thinning is slow in onset and painless without inflammation. Progression can be prevented if treatment is instituted early. There is no specific and efficient treatment. As it develops on autoimmune abnormalities immunosuppressive therapy is proposed. To preserve globe integrity, scleral patch grafting with subsequent immunosuppression is performed.
{"title":"Necrotizing Scleritis without Inflammation (Scleromalacia Perforans): A Case Report","authors":"Manal Bouggar, H. Brarou, Z. Chaibi, Y. Mouzari, Abdelbare Oubaaz","doi":"10.36347/sjmcr.2024.v12i04.013","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.013","url":null,"abstract":"Scleromalacia perforans SP is a rare ocular manifestation of rheumatoid arthritis which can potentially lead to blindness and is a late consequence in the course of the disease; in deed it is most common in elderly female with long-term rheumatoid arthritis, but it was also observed with other systemic diseases. It presents as a blackish blue hue visible through a thin sclera. scleral thinning is slow in onset and painless without inflammation. Progression can be prevented if treatment is instituted early. There is no specific and efficient treatment. As it develops on autoimmune abnormalities immunosuppressive therapy is proposed. To preserve globe integrity, scleral patch grafting with subsequent immunosuppression is performed.","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140708512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-13DOI: 10.36347/sjmcr.2024.v12i04.012
Manal Bouggar, H. Brarou, Z. Chaibi, Y. Mouzari, Abdelbare Oubaaz
Acute zonal ocular outer retinopathy (AZOOR) is a rare disease, usually manifested by persistent photopsia, reduced visual acuity, asymmetric visual field loss. A 46 years old female patient presented to our department for investigation of a slowly progressive decline in visual acuity over several years with no other associated signs. Best corrected visual acuity was 1/10 in the right eye and 8/10 in the left eye; fundoscopic examination revealed an extensive, poorly demarcated peripapillary depigmentation halo with scattered pigment clots, the oct showed atrophy of the outer retina, including interruption of the ellipsoid zone and the outer nuclear layer in the affected areas, with foveal sparing. The patient was treated with steroidal anti-inflammatory drugs, but with no obvious response.
{"title":"Azoor Acute Zonal Ocular Outer Retinitis: A Case Report and Literature Review","authors":"Manal Bouggar, H. Brarou, Z. Chaibi, Y. Mouzari, Abdelbare Oubaaz","doi":"10.36347/sjmcr.2024.v12i04.012","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.012","url":null,"abstract":"Acute zonal ocular outer retinopathy (AZOOR) is a rare disease, usually manifested by persistent photopsia, reduced visual acuity, asymmetric visual field loss. A 46 years old female patient presented to our department for investigation of a slowly progressive decline in visual acuity over several years with no other associated signs. Best corrected visual acuity was 1/10 in the right eye and 8/10 in the left eye; fundoscopic examination revealed an extensive, poorly demarcated peripapillary depigmentation halo with scattered pigment clots, the oct showed atrophy of the outer retina, including interruption of the ellipsoid zone and the outer nuclear layer in the affected areas, with foveal sparing. The patient was treated with steroidal anti-inflammatory drugs, but with no obvious response.","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140707656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-13DOI: 10.36347/sjmcr.2024.v12i04.015
S. Kirami, Y. Bouktib, A. Elhajjami, B. Boutakioute, M. Idrissi, N. I. Elgannouni
Infective endocarditis is an infection with potentially deadly consequences, perivalvular psudoaneurysm remain a very rare complication associated with high mortality. Thoracic CT angiography, in addition to echocardiography, serves as a powerful tool in the exploration and characterization of this vascular complication, guiding further management.
{"title":"Periprothetic Circulating Pseudoaneurysm of the Aortic Root: A Complication of Infective Endocarditis","authors":"S. Kirami, Y. Bouktib, A. Elhajjami, B. Boutakioute, M. Idrissi, N. I. Elgannouni","doi":"10.36347/sjmcr.2024.v12i04.015","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.015","url":null,"abstract":"Infective endocarditis is an infection with potentially deadly consequences, perivalvular psudoaneurysm remain a very rare complication associated with high mortality. Thoracic CT angiography, in addition to echocardiography, serves as a powerful tool in the exploration and characterization of this vascular complication, guiding further management.","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140707802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-13DOI: 10.36347/sjmcr.2024.v12i04.011
Moustapha Etape, Mamfoumbi Mbadinga Noel Juslin, Paul Koulemou, Badr Chalouah, Hamza Kettani, Ekono Nna Albert Patrick, Assessa Essa Fabrice, Ngbwa Denise Edith Tatiana, A. Bennis, O. Zaddoug
Synovial sarcoma are extremely rare malignant tumors of soft extra-skeletal tissue accounting for less than 1% of all malignant tumors. Despite their name, they do not arise from synovial tissue, and their pathogenesis remains unknown. The knee and ankle are the most common sites of occurrence. Due to unclear risk factors, no screening recommendations currently exist. They are characterized by an unpredictable course; hence, multidisciplinary management must be initiated at an early stage in order to improve prognosis. The mainstay of treatment is wide surgical excision, which can often be challenging, requiring the sacrifice of noble structures, while reconstructive surgery can be laborious. The presence of pulmonary metastasis is an indication of poor prognosis. Herein, we report a rare case of a localized elbow synovial sarcoma in a 48-year-old woman with no comorbidity. She underwent surgery for complete tumor removal and had an uncomplicated post-operative follow-up.
{"title":"A Rare Tumor in a Rare Localization: Elbow Synovial Sarcoma","authors":"Moustapha Etape, Mamfoumbi Mbadinga Noel Juslin, Paul Koulemou, Badr Chalouah, Hamza Kettani, Ekono Nna Albert Patrick, Assessa Essa Fabrice, Ngbwa Denise Edith Tatiana, A. Bennis, O. Zaddoug","doi":"10.36347/sjmcr.2024.v12i04.011","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.011","url":null,"abstract":"Synovial sarcoma are extremely rare malignant tumors of soft extra-skeletal tissue accounting for less than 1% of all malignant tumors. Despite their name, they do not arise from synovial tissue, and their pathogenesis remains unknown. The knee and ankle are the most common sites of occurrence. Due to unclear risk factors, no screening recommendations currently exist. They are characterized by an unpredictable course; hence, multidisciplinary management must be initiated at an early stage in order to improve prognosis. The mainstay of treatment is wide surgical excision, which can often be challenging, requiring the sacrifice of noble structures, while reconstructive surgery can be laborious. The presence of pulmonary metastasis is an indication of poor prognosis. Herein, we report a rare case of a localized elbow synovial sarcoma in a 48-year-old woman with no comorbidity. She underwent surgery for complete tumor removal and had an uncomplicated post-operative follow-up.","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140706919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-13DOI: 10.36347/sjmcr.2024.v12i04.014
S. Kirami, M. Benzalim, I. Azzahiri, S. Alj
Synovial osteochondromatosis is an uncommon and chronic condition characterized by a metaplasia of the synovium leading to the formation of cartilaginous or osteocartilaginous bodies in a joint and less commonly, bursa or a tendon sheath. The imaging appearances are variable depending on the stage of the disease. Its development in the peritrochanteric femoral bursa remains exceptional. To our knowledge, this localisation has not been previously described. We present in this work the case of synovial chondromatosis of péritrontéric left femoral bursae diagnosed in a 55-year-old woman. Hip pain was the main symptom. The diagnosis was confirmed by computed tomography (CT) and magnetic resonance imaging (MRI). A breef review of the litterature was also performed to recall the main imaging caracteristics of this rare localisation.
{"title":"Synovial Osteochondromatosis of the Peritrochanteric Femoral Bursa: A Case Report","authors":"S. Kirami, M. Benzalim, I. Azzahiri, S. Alj","doi":"10.36347/sjmcr.2024.v12i04.014","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.014","url":null,"abstract":"Synovial osteochondromatosis is an uncommon and chronic condition characterized by a metaplasia of the synovium leading to the formation of cartilaginous or osteocartilaginous bodies in a joint and less commonly, bursa or a tendon sheath. The imaging appearances are variable depending on the stage of the disease. Its development in the peritrochanteric femoral bursa remains exceptional. To our knowledge, this localisation has not been previously described. We present in this work the case of synovial chondromatosis of péritrontéric left femoral bursae diagnosed in a 55-year-old woman. Hip pain was the main symptom. The diagnosis was confirmed by computed tomography (CT) and magnetic resonance imaging (MRI). A breef review of the litterature was also performed to recall the main imaging caracteristics of this rare localisation.","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140708125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-10DOI: 10.36347/sjmcr.2024.v12i04.010
F. Ezzaky, M. Ramzi, S. Hosni, A. Dendane, A. Amrani, Z. Alami, T. Madhi
Osteoid osteomas are benign bone-forming tumors that typically occur in children (particularly adolescents). They have a characteristic lucent nidus <1.5 or 2 cm and surrounding osteosclerotic reaction, which classically causes night pain that is relieved by the use of the location of osteoid osteoma in the ankle is rare. We report the case of a young boy who had an osteoid osteoma of the talus.
{"title":"Osteoid Osteoma of the Talus: Case Report","authors":"F. Ezzaky, M. Ramzi, S. Hosni, A. Dendane, A. Amrani, Z. Alami, T. Madhi","doi":"10.36347/sjmcr.2024.v12i04.010","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.010","url":null,"abstract":"Osteoid osteomas are benign bone-forming tumors that typically occur in children (particularly adolescents). They have a characteristic lucent nidus <1.5 or 2 cm and surrounding osteosclerotic reaction, which classically causes night pain that is relieved by the use of the location of osteoid osteoma in the ankle is rare. We report the case of a young boy who had an osteoid osteoma of the talus.","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140718597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-10DOI: 10.36347/sjmcr.2024.v12i04.009
Sara Dilal, S. Mechhor, Manal Cherkaoui Malki, H. Elbacha, N. Benzzoubeir, Ikram Errabih
Introduction: Metronidazole, a commonly used nitroimidazole antibiotic, is associated with various side effects, including neurological complications such as toxic peripheral neuropathy, cerebellar dysfunction, and seizures. Despite its widespread use, serious neurological effects can occur, necessitating prompt diagnosis and discontinuation of treatment. Observation: We present the case of a 26-year-old patient with colonic Crohn's disease treated with metronidazole, who experienced both central and peripheral neurotoxicity after a cumulative exposure of 42 days. The patient presented with convulsive seizures and paresthesia of the lower limbs, prompting a comprehensive etiological work-up, including metabolic assessments, imaging studies, and lumbar puncture. The absence of abnormalities in diagnostic tests, coupled with symptom improvement upon discontinuation of metronidazole, led to the diagnosis of metronidazole-induced neurotoxicity. Discussion: Metronidazole-induced neurotoxicity is a known but underreported complication, affecting both the central and peripheral nervous systems. The duration of treatment before symptom onset can vary, and the association of central and peripheral symptoms is rare. Radiological findings, often observed on T2-weighted MRI, may show characteristic lesions, but their absence does not exclude the diagnosis. The pathogenesis involves metronidazole's ability to cross the blood-brain barrier, leading to the generation of superoxide radicals and axonal swelling. Prompt recognition and discontinuation of metronidazole are crucial for potential symptom resolution. Conclusion: This case underscores the importance of considering metronidazole-induced neurotoxicity in patients presenting with neurological symptoms during or after metronidazole treatment. A high clinical suspicion, coupled with a detailed evaluation and, if needed, discontinuation of metronidazole, is vital for timely diagnosis and management. Recognition of this ........
{"title":"Metronidazole-Induced Neurotoxicity: A Rare Case Report","authors":"Sara Dilal, S. Mechhor, Manal Cherkaoui Malki, H. Elbacha, N. Benzzoubeir, Ikram Errabih","doi":"10.36347/sjmcr.2024.v12i04.009","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.009","url":null,"abstract":"Introduction: Metronidazole, a commonly used nitroimidazole antibiotic, is associated with various side effects, including neurological complications such as toxic peripheral neuropathy, cerebellar dysfunction, and seizures. Despite its widespread use, serious neurological effects can occur, necessitating prompt diagnosis and discontinuation of treatment. Observation: We present the case of a 26-year-old patient with colonic Crohn's disease treated with metronidazole, who experienced both central and peripheral neurotoxicity after a cumulative exposure of 42 days. The patient presented with convulsive seizures and paresthesia of the lower limbs, prompting a comprehensive etiological work-up, including metabolic assessments, imaging studies, and lumbar puncture. The absence of abnormalities in diagnostic tests, coupled with symptom improvement upon discontinuation of metronidazole, led to the diagnosis of metronidazole-induced neurotoxicity. Discussion: Metronidazole-induced neurotoxicity is a known but underreported complication, affecting both the central and peripheral nervous systems. The duration of treatment before symptom onset can vary, and the association of central and peripheral symptoms is rare. Radiological findings, often observed on T2-weighted MRI, may show characteristic lesions, but their absence does not exclude the diagnosis. The pathogenesis involves metronidazole's ability to cross the blood-brain barrier, leading to the generation of superoxide radicals and axonal swelling. Prompt recognition and discontinuation of metronidazole are crucial for potential symptom resolution. Conclusion: This case underscores the importance of considering metronidazole-induced neurotoxicity in patients presenting with neurological symptoms during or after metronidazole treatment. A high clinical suspicion, coupled with a detailed evaluation and, if needed, discontinuation of metronidazole, is vital for timely diagnosis and management. Recognition of this ........","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140717015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.36347/sjmcr.2024.v12i04.008
Sara Dilal, S. Mechhor, Manal Cherkaoui Malki, H. Elbacha, N. Benzzoubeir, Ikram Errabih
Introduction: Waldmann's disease, or primary intestinal lymphangiectasia (PIL), is an uncommon condition characterized by digestive lymphatic dilatations, predominantly observed in the pediatric population and rarely in adults. First described in 1961, its etiology remains unknown, and it presents with diverse manifestations, from chronic diarrhea to ascites. Diagnosis involves intestinal biopsies and radiological assessments, with treatment primarily focused on dietary modifications and, in exceptional cases, surgery. Observation: This report details a unique case of Waldmann's disease diagnosed in a 52-year-old man with a history of type 2 diabetes. Presenting with a complex clinical picture including generalized edematous syndrome, chronic diarrhea, and ascitic manifestations, the patient underwent a comprehensive diagnostic evaluation ruling out renal, hepatic, and cardiac causes. Endoscopic examinations revealed multiple duodenal lymphangiectasias, supporting the diagnosis of exudative gastroenteropathy. The patient responded positively to dietary interventions with medium-chain triglycerides, showing a significant regression of symptoms. Discussion: Waldmann's disease, a rare pathology with unknown prevalence, typically manifests in early childhood. However, the case presented here highlights the atypical onset in adulthood, emphasizing the importance of considering this diagnosis in cases of exudative enteropathy with an early onset. Clinical signs, including lower limb edema, chronic diarrhea, and visceral effusions, may vary, making a definitive diagnosis challenging. Diagnostic modalities such as imaging, biopsies, and specialized tests like Alpha-1 antitrypsin clearance play a crucial role in confirming the condition. Complications, including the risk of neoplasia and immunological abnormalities, require vigilant follow-up. Treatment primarily involves medical and dietary approaches, with encouraging results. Surgical resection may be considered .........
{"title":"Exudative Enteropathy Revealing Waldmann’s Disease: A Rare Case Report","authors":"Sara Dilal, S. Mechhor, Manal Cherkaoui Malki, H. Elbacha, N. Benzzoubeir, Ikram Errabih","doi":"10.36347/sjmcr.2024.v12i04.008","DOIUrl":"https://doi.org/10.36347/sjmcr.2024.v12i04.008","url":null,"abstract":"Introduction: Waldmann's disease, or primary intestinal lymphangiectasia (PIL), is an uncommon condition characterized by digestive lymphatic dilatations, predominantly observed in the pediatric population and rarely in adults. First described in 1961, its etiology remains unknown, and it presents with diverse manifestations, from chronic diarrhea to ascites. Diagnosis involves intestinal biopsies and radiological assessments, with treatment primarily focused on dietary modifications and, in exceptional cases, surgery. Observation: This report details a unique case of Waldmann's disease diagnosed in a 52-year-old man with a history of type 2 diabetes. Presenting with a complex clinical picture including generalized edematous syndrome, chronic diarrhea, and ascitic manifestations, the patient underwent a comprehensive diagnostic evaluation ruling out renal, hepatic, and cardiac causes. Endoscopic examinations revealed multiple duodenal lymphangiectasias, supporting the diagnosis of exudative gastroenteropathy. The patient responded positively to dietary interventions with medium-chain triglycerides, showing a significant regression of symptoms. Discussion: Waldmann's disease, a rare pathology with unknown prevalence, typically manifests in early childhood. However, the case presented here highlights the atypical onset in adulthood, emphasizing the importance of considering this diagnosis in cases of exudative enteropathy with an early onset. Clinical signs, including lower limb edema, chronic diarrhea, and visceral effusions, may vary, making a definitive diagnosis challenging. Diagnostic modalities such as imaging, biopsies, and specialized tests like Alpha-1 antitrypsin clearance play a crucial role in confirming the condition. Complications, including the risk of neoplasia and immunological abnormalities, require vigilant follow-up. Treatment primarily involves medical and dietary approaches, with encouraging results. Surgical resection may be considered .........","PeriodicalId":509943,"journal":{"name":"Scholars Journal of Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140722852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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