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Autoimmune Polyendocrinopathy Type 2 (PEA Type) Associated with Biermer's Disease: Report of a Case and Review of the Literature 与比默氏病相关的自身免疫性多内分泌病 2 型(PEA 型):病例报告与文献综述
Pub Date : 2024-04-08 DOI: 10.36347/sjmcr.2024.v12i04.007
Colna Antonio N´fad, Togo Mamadu, Pr. Yassine Er-Rahali, Pr. Ahmed Anass Guerboub
Autoimmune polyendocrinopathy type II (AIEP II) is a more common syndrome that appears mainly in adults. It combines several autoimmune pathologies including Addison's disease and autoimmune thyroid disease (Schmidt syndrome) and/or type 1 diabetes (Carpenter syndrome). We report the case of a 16-year-old patient with notable familial pathological ATCD: Father followed by high blood pressure under antihypertensive treatment and type 2 diabetes under oral anti-diabetes medication. Mother followed for hypothyroidism under hormone replacement treatment with levothyroxine. The patient was followed for hypothyroidism for 2 years, hospitalized in our training for suspicion of adrenal insufficiency. Clinically the patient was asthenic, she had arthralgia and myalgia with anorexia contrasting an appetite for salt with notion of fasting hypoglycemia without melanoderma or vitiligo, the rest of the clinical examination was unremarkable. Weight: 65 kg; Height: 1.69 m; BMI: 23Kg/m²; TT: 70 cm; Pulse: 64 bpm. BP: 110/60 mm Hg in the right arm standing and lying down. Biological exploration found low 08 h plasma cortisol with high ACTH, high TSH and anti-TPO antibodies, and macrocytic normochromic anemia at 8 g/dl with anti-parietal cell antibodies and intrinsic factor have positive. whose explorations were in favor of Biermer's disease. The diagnosis of PEA type 2 was made. The treatment recommended: hormonal replacement of adrenal and thyroid insufficiency as well as vitamin B12 injections with good clinical and biological progress.
自身免疫性多内分泌病 II 型(AIEP II)是一种更常见的综合征,主要出现在成年人身上。它结合了多种自身免疫性病变,包括阿狄森氏病和自身免疫性甲状腺疾病(施密特综合征)和/或 1 型糖尿病(卡彭特综合征)。我们报告了一例 16 岁患者的病例,该患者具有明显的家族病理 ATCD:父亲因高血压接受降压治疗,2 型糖尿病接受口服抗糖尿病药物治疗。母亲因甲状腺功能减退接受左甲状腺素激素替代治疗。患者因甲状腺功能减退症接受了两年的随访,因怀疑肾上腺功能不全而在我院住院治疗。临床上,该患者体质虚弱,有关节痛和肌痛,伴有厌食,食盐量少,有空腹低血糖症状,无黑色素瘤或白癜风,其他临床检查无异常。体重:65 千克;身高:1.69 米;体重指数:23 千克/平方米;TT:70 厘米;脉搏:64 次/分。血压:右臂站立和平卧时均为 110/60 mm Hg。生物学检查发现 08 h 血浆皮质醇偏低,ACTH 偏高,促甲状腺激素(TSH)和抗-TPO 抗体偏高,大红细胞正常色素性贫血(8 g/dl),抗顶叶细胞抗体和内在因子呈阳性。诊断结果为 PEA 2 型。治疗建议:肾上腺和甲状腺功能不全的激素替代以及维生素 B12 注射,临床和生物学进展良好。
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引用次数: 0
Vaginal Angiomyofibroblastoma Associated with Uterine Pathology about a Case 阴道血管肌纤维母细胞瘤伴发子宫病变一例
Pub Date : 2024-04-05 DOI: 10.36347/sjmcr.2024.v12i04.005
I. Traoré, S. Boudhas, M. Idrissi, N. Mamouni, S. Errarhay, C. Bouchikhi, A. Banani
Angiomyofibroblastoma is a rare benign mesenchymal tumor. Angiomyofibroblastism is a generally painless tumor, most patients consult for the genes caused the tumor in cases where they are large. We report a case of vaginal location of 3 cm in a 67 years old patient discovered during investigation of abnormal uterine bleeding. The patient benefited complete excision of the tumor, surgical hysteroscopy and hysterectomy by surgical laparoscopy. Angiomyofibroblastoma can be associated with a uterine pathology whose intake in charge cannot be dissociated from it.
血管肌纤维母细胞瘤是一种罕见的良性间充质肿瘤。血管肌纤维母细胞瘤一般是一种无痛性肿瘤,大多数患者在肿瘤较大时会咨询肿瘤的基因。我们报告了一例在检查异常子宫出血时发现的 3 厘米阴道肿瘤,患者 67 岁。患者接受了肿瘤完全切除术、宫腔镜手术和腹腔镜子宫切除术。血管肌纤维母细胞瘤可能与子宫病变有关,而子宫病变与血管肌纤维母细胞瘤的摄入量是分不开的。
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引用次数: 0
Unusual Unveiling: Hodgkin's Lymphoma Manifesting as Chylous Ascites 不寻常的揭幕表现为乳糜腹水的霍奇金淋巴瘤
Pub Date : 2024-04-05 DOI: 10.36347/sjmcr.2024.v12i04.004
Bounouar Ibtissam, ElManjra Chama, N. Oussama, Lairani Fatima Ezzahra, AitErrami Adil, Oubaha Sophia, Samlani Zouhour, K. Khadija
Chylous ascites, an infrequent manifestation of ascites characterized by a triglyceride-rich milky fluid, is associated with lymphatic system disruption resulting from obstruction or post-traumatic injury. It is an unusual complication of lymphomas, which nonetheless represent the primary cause in adults in developed countries, often due to abdominal lymphatic obstruction. We present the case of a 71-year-old woman who presented with abdominal distension attributed to chylous ascites, ultimately revealing non-Hodgkin lymphoma. Palpable peripheral lymph nodes and enlarged lombo-aortic lymph nodes on abdominal CT scans indicated the diagnosis of stage IV centrofollicular non-Hodgkin lymphoma (Ann Arbor classification). The chylous ascites resolved with chemotherapy treatment.
乳糜腹水是一种不常见的腹水表现,以富含甘油三酯的乳白色液体为特征,与淋巴系统阻塞或创伤后导致的淋巴系统破坏有关。腹水是淋巴瘤的一种罕见并发症,但在发达国家,淋巴瘤是成人腹水的主要原因,通常是由于腹腔淋巴管阻塞所致。我们介绍了一例 71 岁女性的病例,她因乳糜腹水导致腹胀,最终发现患有非霍奇金淋巴瘤。腹部 CT 扫描显示可触及周围淋巴结和肿大的主动脉淋巴结,诊断为 IV 期中心叶状非霍奇金淋巴瘤(Ann Arbor 分类)。化疗后,乳糜腹水消退。
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引用次数: 0
Pulmonary Hydatidosis and Hydatid Pulmonary Embolism 肺水肿病和水肿性肺栓塞
Pub Date : 2024-04-05 DOI: 10.36347/sjmcr.2024.v12i04.006
Y. Amchich, H. ouzzani, A. Rhorfi, A. Abid
We present an extremely rare case of a old man 52 answith hydatid pulmonary embolism caused by a direct invasion of the pulmonary artery by a hydatid cyst. Even if it is a benign parasitic disease, it can lead to serious complications such as arterial, systemic, or multivisceral dissemination or being responsible for an anaphylactic shock. Because of the clinical polymorphism, the diagnosis can be delayed. Therefore, A chest CT angiography is the gold standard for the positive diagnosis.
我们介绍了一例极为罕见的病例,患者是一名 52 岁的老人,因水包虫囊肿直接侵入肺动脉而导致肺栓塞。即使这是一种良性寄生虫病,也可能导致严重的并发症,如动脉、全身或多脏器播散,或引起过敏性休克。由于临床多态性,诊断可能会被延误。因此,胸部 CT 血管造影是确诊的金标准。
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引用次数: 0
Ogilvie Syndrome Induced by Antidepressant: A Case Report 抗抑郁药诱发的奥格尔维综合征:病例报告
Pub Date : 2024-04-02 DOI: 10.36347/sjmcr.2024.v12i04.003
O. Hadadia, M. Haida, F. Lairani, O. Nacir, A. Errami, S. Oubaha, Z. Samlani, K. Krati
Ogilvie’s Syndrome is a rare entity in which the colon becomes massively dilated without apparent mechanical obstruction. Patients on antidepressant drugs commonly complain of dryness of the mouth, tremors, blurring of vision and constipation, which are attributed to the anticholinergic action of the drugs. We report a case of a 39-year-old female case of gastrointestinal complication (pseudo-intestinal obstruction), which are considered rare according to a review of the literature.
奥格尔维综合征(Ogilvie's Syndrome)是一种罕见的结肠大面积扩张而无明显机械性梗阻的病症。服用抗抑郁药物的患者通常会主诉口干、震颤、视力模糊和便秘,这是因为药物的抗胆碱能作用所致。我们报告了一例 39 岁女性的胃肠道并发症(假性肠梗阻)病例,根据文献综述,这种情况非常罕见。
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引用次数: 0
Unusual Clinical Synergy: Crohn's Disease, Behçet's Disease, and Ankylosing Spondylodiscitis – A Comprehensive Look at Interactions 不寻常的临床协同作用:克罗恩病、白塞氏病和强直性脊柱盘炎--全面了解相互作用
Pub Date : 2024-04-01 DOI: 10.36347/sjmcr.2024.v12i04.001
D. Rajih, H. E. Marmouk, F. Lairani, O. Nacir, A. Errami, S. Oubaha, Z. Samlani, K. Krati
Crohn's disease, Behçet's disease, and ankylosing spondylodiscitis are inflammatory conditions that can pose therapeutic challenges when they occur together. Treatment decisions should be guided by the clinical presentation of each condition, its level of activity, and severity. Several points regarding this combined management need to be addressed. We report the case of a 37-year-old man diagnosed with Crohn's disease, Behçet's disease, and ankylosing spondylodiscitis, aiming to present the diagnostic approach and therapeutic specificities of this association.
克罗恩病、贝赫切特氏病和强直性脊柱盘炎都是炎症性疾病,当它们同时出现时会给治疗带来挑战。治疗决策应根据每种疾病的临床表现、活动程度和严重程度而定。关于这种合并治疗,有几点需要注意。我们报告了一名 37 岁男子的病例,他被诊断患有克罗恩病、白塞氏病和强直性脊柱盘炎,旨在介绍这种合并症的诊断方法和治疗特异性。
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引用次数: 0
Testicular cancer in undescended testicle: A Review of Literature and Case Report 未降睾丸中的睾丸癌:文献综述与病例报告
Pub Date : 2024-04-01 DOI: 10.36347/sjmcr.2024.v12i04.002
Mehedra Anass, Babty Mouftah, Fouimtizi Jaafar, Slaoui Amine, Karmouni Tarik, E. Khalid, Koutani Abdellatif Iben Attya, Andaloussi Ahmed
This clinical case involves a 52-year-old married patient with two children who presented initially with left-sided pelvic pain, leading to the discovery of a tumor on a cryptorchid testicle. Further evaluation revealed a suspicious lesion, indicating degeneration of a testicle in an aberrant position. Surgical intervention via laparoscopic orchidectomy confirmed a seminoma, emphasizing the association between cryptorchidism and testicular germ cell tumors. This case underscores the importance of early diagnosis and management of cryptorchidism to mitigate the risk of testicular malignancies, highlighting the necessity for timely surgical intervention and careful monitoring of patients with undescended testicles.
本临床病例涉及一名 52 岁的已婚患者,有两个孩子。患者最初出现左侧盆腔疼痛,随后发现隐睾上长有肿瘤。进一步的评估发现了一个可疑的病灶,表明睾丸位置异常发生了退化。通过腹腔镜睾丸切除术进行手术干预,证实了这是一个精原细胞瘤,强调了隐睾症与睾丸生殖细胞肿瘤之间的关联。本病例强调了早期诊断和治疗隐睾症以降低睾丸恶性肿瘤风险的重要性,突出了对睾丸未降患者进行及时手术干预和仔细监测的必要性。
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引用次数: 0
Deep Neck Infection: A Case Series 颈部深部感染病例系列
Pub Date : 2024-02-15 DOI: 10.36347/sjmcr.2024.v12i02.013
Ageng Beta Prawatya, Dheo Aliffanandy P. N, Naura Salsabila, Oxa Aqilla Putri S, Ulayya Azzah Nadiroh, Iwan Setiawan Adji
Background: Deep neck abscess is a collection of pus (pus) in the potential space between the fascia of the deep neck due to spread from various sources of infection, such as teeth, mouth, throat, paranasal sinuses, ears and neck. Various spaces can be a place for deep neck abscesses including the submandibular, peritonsillar, parapharyngeal, retropharyngeal, submental, parotid, anterior visceral, carotid, and masseter spaces. Inflammation or damage to chronic problem teeth can lead to complications of deep neck abscesses. The main complaint that causes sufferers to come to the hospital is dysphagia, which is difficulty swallowing due to the pain felt by the patient. These complaints can also be accompanied by trismus, stridor caused by tracheal compression, to airway obstruction. Purpose: To determine the progressivity of deep neck abscess so that it can provide medical management until operative incision and drainage. Case report: We report 5 cases of deep neck abscess with management according to the progress of each case. Conclusion: The most common cause or etiology that can lead to deep neck abscess is toothache. Management of deep neck abscess, starting with the administration of empirical antibiotics which is the first step to reduce the infection of bacteria that produce beta lactamase. In deep neck abscess, medical therapy can be given in the form of an antibiotic combination of ceftriaxone with metronidazole, or meropenem with metronidazole as well as surgery in the form of incision and drainage. Treatment can be chosen based on the presence or absence of warning signs and signs of complications. Incision and drainage is performed when complaints do not improve after administration of antibiotics, multiple abscesses and airway obstruction that threatens the patient's life.
背景:颈深部脓肿是指由于各种感染源(如牙齿、口腔、咽喉、鼻旁窦、耳朵和颈部)的扩散而在颈深部筋膜之间的潜在空间聚集的脓(脓液)。各种空间都可能成为颈深部脓肿的发源地,包括颌下、腹腔周围、咽旁、咽后、门下、腮腺、前内脏、颈动脉和腮腺间隙。慢性问题牙齿的炎症或损伤可导致颈部深部脓肿的并发症。导致患者来医院就诊的主要原因是吞咽困难,即由于患者感到疼痛而导致吞咽困难。这些主诉还可能伴有气管受压引起的哮鸣音和气道阻塞。目的:确定颈部深部脓肿的进展情况,以便在手术切开引流前提供药物治疗。病例报告:我们报告了 5 例颈部深部脓肿病例,并根据每个病例的进展情况进行了处理。结论导致颈深部脓肿最常见的原因或病因是牙痛。治疗深部颈部脓肿,首先要使用经验性抗生素,这是减少产生内酰胺酶的细菌感染的第一步。对于深部颈部脓肿,可采用头孢曲松联合甲硝唑或美罗培南联合甲硝唑的抗生素联合疗法,以及切开引流的手术疗法。可根据有无预警信号和并发症迹象选择治疗方法。当使用抗生素后症状仍无改善、多发性脓肿和气道阻塞危及患者生命时,就需要进行切开引流术。
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引用次数: 0
Hemorrhagic Hepatic Cyst Mimicking a Cystic Neoplasm: Case Report 模仿囊性肿瘤的出血性肝囊肿:病例报告
Pub Date : 2024-02-12 DOI: 10.36347/sjmcr.2024.v12i02.012
I. Koti, A. Benhamdane, S. Mrabti, R. Chaibi, S. Hdiye, I. Mouslim, T. Addajou, F. Rouibaa, H. Seddik
Background: Intracystic hemorrhage is an extremely rare complication of simple hepatic cysts. Clinical symptomatology is non-specific, and imaging frequently mimics a biliary cystadenoma or cystadenocarcinoma, which makes it challenging from a diagnostic point of view to an appropriate therapeutic approach. In this report, we present a case of a simple hemorrhagic hepatic cyst mimicking a cystic neoplasm. Case Report: 48-year-old men was referred to our hospital for periumbilical abdominal pain with asthenia and 11 kg weight loss. His physical examination and laboratory findings were unremarkable. Carcinoembryonic antigen concentration was three times higher than normal. Abdominal ultrasonography demonstrated an impure cystic mass measuring 120 x 96 x 108 mm on hepatic segments VI and VII. Abdominal CT showed a cystic mass at the liver possibly related to a cystadenocarcinoma. Abdominal MRI revealed a cystic mass with lobulated contours, located in segments VII, VIII and part of VI, measuring 11.8 x11.4 cm long axis, heterogeneous signal with intense fluid towards the top in T1 and T2 and intense fluid towards the decline in T2 and T1, with the appearance of a small inferior septum slightly enhanced after injection. These findings did not exclude the possibility of malignant cystic tumor, such as biliary cystadenocarcinoma. Therefore, endoscopic ultrasound showed a cystic lesion developing in the liver, with a thickened wall in places, mainly adjacent to an intracystic nodule of 25 mm, this nodule continued with the wall. Biopsy performed using a 22G ultrasound. Aspiration of liquid: string test negative. Pathological examination confirmed a hemorrhagic biliary cyst and there was no tumor tissue. We observed a significant improvement in symptoms and reduction in cyst size after needle aspiration and we decided to adopt a conservative approach. The patient was followed and one year later, the patient remained in good condition without any complaints. ................
背景:囊内出血是单纯性肝囊肿极为罕见的并发症。临床症状无特异性,影像学表现常模仿胆囊腺瘤或胆囊腺癌,这使得从诊断角度到适当的治疗方法都具有挑战性。在本报告中,我们介绍了一例模仿囊性肿瘤的单纯出血性肝囊肿病例。病例报告:48 岁的男性因脐周腹痛、气喘和体重下降 11 公斤而被转诊至我院。他的体格检查和实验室检查结果均无异常。癌胚抗原浓度是正常值的三倍。腹部超声波检查显示,肝脏 VI 和 VII 段有一个 120 x 96 x 108 毫米的不纯囊性肿块。腹部 CT 显示肝脏处有一个囊性肿块,可能与囊腺癌有关。腹部核磁共振成像显示,位于肝脏第VII、VIII节段和第VI节段部分的囊性肿块呈分叶轮廓,长轴尺寸为11.8 x 11.4厘米,T1和T2呈异质信号,顶部有较强的液体,T2和T1呈较弱的液体,注射后出现小的下隔膜,略有增强。这些发现并不排除恶性囊性肿瘤的可能性,如胆囊腺癌。因此,内镜超声检查显示肝脏内出现囊性病变,局部囊壁增厚,主要与一个 25 毫米的囊内结节相邻,该结节与囊壁相连。使用 22G 超声波进行了活检。抽取液体:串联试验阴性。病理检查证实为出血性胆道囊肿,没有肿瘤组织。我们观察到针吸术后症状明显改善,囊肿缩小,因此决定采取保守治疗。我们对患者进行了随访,一年后,患者情况依然良好,没有任何不适。................
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引用次数: 0
Hemorrhagic Hepatic Cyst Mimicking a Cystic Neoplasm: Case Report 模仿囊性肿瘤的出血性肝囊肿:病例报告
Pub Date : 2024-02-12 DOI: 10.36347/sjmcr.2024.v12i02.012
I. Koti, A. Benhamdane, S. Mrabti, R. Chaibi, S. Hdiye, I. Mouslim, T. Addajou, F. Rouibaa, H. Seddik
Background: Intracystic hemorrhage is an extremely rare complication of simple hepatic cysts. Clinical symptomatology is non-specific, and imaging frequently mimics a biliary cystadenoma or cystadenocarcinoma, which makes it challenging from a diagnostic point of view to an appropriate therapeutic approach. In this report, we present a case of a simple hemorrhagic hepatic cyst mimicking a cystic neoplasm. Case Report: 48-year-old men was referred to our hospital for periumbilical abdominal pain with asthenia and 11 kg weight loss. His physical examination and laboratory findings were unremarkable. Carcinoembryonic antigen concentration was three times higher than normal. Abdominal ultrasonography demonstrated an impure cystic mass measuring 120 x 96 x 108 mm on hepatic segments VI and VII. Abdominal CT showed a cystic mass at the liver possibly related to a cystadenocarcinoma. Abdominal MRI revealed a cystic mass with lobulated contours, located in segments VII, VIII and part of VI, measuring 11.8 x11.4 cm long axis, heterogeneous signal with intense fluid towards the top in T1 and T2 and intense fluid towards the decline in T2 and T1, with the appearance of a small inferior septum slightly enhanced after injection. These findings did not exclude the possibility of malignant cystic tumor, such as biliary cystadenocarcinoma. Therefore, endoscopic ultrasound showed a cystic lesion developing in the liver, with a thickened wall in places, mainly adjacent to an intracystic nodule of 25 mm, this nodule continued with the wall. Biopsy performed using a 22G ultrasound. Aspiration of liquid: string test negative. Pathological examination confirmed a hemorrhagic biliary cyst and there was no tumor tissue. We observed a significant improvement in symptoms and reduction in cyst size after needle aspiration and we decided to adopt a conservative approach. The patient was followed and one year later, the patient remained in good condition without any complaints. ................
背景:囊内出血是单纯性肝囊肿极为罕见的并发症。临床症状无特异性,影像学表现常模仿胆囊腺瘤或胆囊腺癌,这使得从诊断角度到适当的治疗方法都具有挑战性。在本报告中,我们介绍了一例模仿囊性肿瘤的单纯出血性肝囊肿病例。病例报告:48 岁的男性因脐周腹痛、气喘和体重下降 11 公斤而被转诊至我院。他的体格检查和实验室检查结果均无异常。癌胚抗原浓度是正常值的三倍。腹部超声波检查显示,肝脏 VI 和 VII 段有一个 120 x 96 x 108 毫米的不纯囊性肿块。腹部 CT 显示肝脏处有一个囊性肿块,可能与囊腺癌有关。腹部核磁共振成像显示,位于肝脏第VII、VIII节段和第VI节段部分的囊性肿块呈分叶轮廓,长轴尺寸为11.8 x 11.4厘米,T1和T2呈异质信号,顶部有较强的液体,T2和T1呈较弱的液体,注射后出现小的下隔膜,略有增强。这些发现并不排除恶性囊性肿瘤的可能性,如胆囊腺癌。因此,内镜超声检查显示肝脏内出现囊性病变,局部囊壁增厚,主要与一个 25 毫米的囊内结节相邻,该结节与囊壁相连。使用 22G 超声波进行了活检。抽取液体:串联试验阴性。病理检查证实为出血性胆道囊肿,没有肿瘤组织。我们观察到针吸术后症状明显改善,囊肿缩小,因此决定采取保守治疗。我们对患者进行了随访,一年后,患者情况依然良好,没有任何不适。................
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引用次数: 0
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Scholars Journal of Medical Case Reports
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