首页 > 最新文献

World Journal of Otorhinolaryngology - Head and Neck Surgery最新文献

英文 中文
Recovery rates and long‐term olfactory dysfunction following COVID‐19 infection 感染 COVID-19 后的恢复率和长期嗅觉功能障碍
Pub Date : 2024-03-19 DOI: 10.1002/wjo2.163
Melanie Dias, Z. Shaida, N. Haloob, Claire Hopkins
Olfactory dysfunction is one of the most recognized symptoms of COVID‐19, significantly impacting quality of life, particularly in cases where recovery is prolonged. This review aims to explore patterns of olfactory recovery post‐COVID‐19 infection, with particular focus on delayed recovery.Published literature in the English language, including senior author's own work, online and social media platforms, and patients' anecdotal reports.A comprehensive review of the literature was undertaken by the authors with guidance from the senior author with expertise in the field of olfaction.Based on self‐report, an estimated 95% of patients recover their olfactory function within 6 months post‐COVID‐19 infection. However, psychophysical testing detects higher rates of persistent olfactory dysfunction. Recovery has been found to continue for at least 2 years postinfection; negative prognostic indicators include severe olfactory loss in the acute phase, female sex, and older age. Variability in quantitative and qualitative disturbance in prolonged cases likely reflects both peripheral and central pathophysiological mechanisms. Limitations of many of the reviewed studies reflect lack of psychophysical testing and baseline olfactory assessment.Post‐COVID‐19 olfactory dysfunction remains a significant health and psychosocial burden. Emerging evidence is improving awareness and knowledge among clinicians to better support patients through their olfactory rehabilitation, with hope of recovery after several months or years. Further research is needed to better understand the underlying pathogenesis of delayed recovery, identify at risk individuals earlier in the disease course, and develop therapeutic targets.
嗅觉功能障碍是 COVID-19 最公认的症状之一,严重影响生活质量,尤其是在恢复期较长的病例中。本综述旨在探讨感染 COVID-19 后嗅觉恢复的模式,尤其关注延迟恢复的情况。作者在嗅觉领域资深专家的指导下对文献进行了全面综述。然而,心理物理测试发现持续性嗅觉功能障碍的比例更高。研究发现,患者在感染后至少两年内仍可恢复嗅觉功能;预后不良的指标包括急性期嗅觉功能严重减退、女性和高龄。长期病例在数量和质量上的紊乱差异可能反映了外周和中枢的病理生理机制。许多综述研究的局限性在于缺乏心理物理测试和基线嗅觉评估。新出现的证据提高了临床医生的认识和知识水平,从而更好地支持患者进行嗅觉康复,并有望在数月或数年后恢复。为了更好地了解延迟康复的潜在发病机制、在病程早期识别高危人群并开发治疗目标,还需要开展进一步的研究。
{"title":"Recovery rates and long‐term olfactory dysfunction following COVID‐19 infection","authors":"Melanie Dias, Z. Shaida, N. Haloob, Claire Hopkins","doi":"10.1002/wjo2.163","DOIUrl":"https://doi.org/10.1002/wjo2.163","url":null,"abstract":"Olfactory dysfunction is one of the most recognized symptoms of COVID‐19, significantly impacting quality of life, particularly in cases where recovery is prolonged. This review aims to explore patterns of olfactory recovery post‐COVID‐19 infection, with particular focus on delayed recovery.Published literature in the English language, including senior author's own work, online and social media platforms, and patients' anecdotal reports.A comprehensive review of the literature was undertaken by the authors with guidance from the senior author with expertise in the field of olfaction.Based on self‐report, an estimated 95% of patients recover their olfactory function within 6 months post‐COVID‐19 infection. However, psychophysical testing detects higher rates of persistent olfactory dysfunction. Recovery has been found to continue for at least 2 years postinfection; negative prognostic indicators include severe olfactory loss in the acute phase, female sex, and older age. Variability in quantitative and qualitative disturbance in prolonged cases likely reflects both peripheral and central pathophysiological mechanisms. Limitations of many of the reviewed studies reflect lack of psychophysical testing and baseline olfactory assessment.Post‐COVID‐19 olfactory dysfunction remains a significant health and psychosocial burden. Emerging evidence is improving awareness and knowledge among clinicians to better support patients through their olfactory rehabilitation, with hope of recovery after several months or years. Further research is needed to better understand the underlying pathogenesis of delayed recovery, identify at risk individuals earlier in the disease course, and develop therapeutic targets.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"55 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140230936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of betahistine as an add‐on therapy to epley maneuver for benign paroxysmal positional vertigo: A systematic review and meta‐analysis 倍他司汀作为 "pley手法 "的附加疗法对良性阵发性位置性眩晕的疗效:系统综述和荟萃分析
Pub Date : 2024-03-18 DOI: 10.1002/wjo2.161
Renad M Alsolamy, Abdulaziz K. Alaraifi, Yazeed Aloqaili
Epley maneuver is the most effective treatment for benign paroxysmal positional vertigo (BPPV). Betahistine has been shown to be effective in treating BPPV. This systematic review aims to compare the effectiveness of Epley maneuver with betahistine to Epley maneuver alone in reducing residual dizziness in BPPV.Medline, Embase, and CENTRAL.We included randomized controlled trials (RCTs) that compared Epley maneuver with betahistine to Epley maneuver alone for treating BPPV. We evaluated the effectiveness of this intervention using Dizziness Handicap Inventory (DHI), Visual Analog Scale (VAS) for vertigo, and provocation maneuvers. We used the standardized mean difference (SMD) for continuous outcomes and the odds ratio (OR) for the dichotomous outcomes.A total of eight RCTs that enrolled 516 participants were deemed eligible. Administration of betahistine with Epley maneuver showed no clinically significant difference over Epley maneuver alone in DHI score (SMD: −0.11, 95% confidence interval [CI], −0.57 to 0.34, p = 0.63, I2 = 79%), VAS scores (SMD: −0.57, 95% CI, −1.57 to 0.43, p = 0.26, I2 = 89%), or on provocation maneuvers (OR: 1.84, 95% CI, 0.92 to 3.68, p = 0.08, I2 = 0%) after 1 week of betahistine administration. However, participants who received betahistine combined with Epley maneuver showed a statistically significant reduction in VAS scores after 4 weeks of betahistine administration (SMD: −0.89, 95% CI, −1.30 to −0.49, p < 0.0001, I2 = 33%).Combining betahistine with Epley maneuver could improve the outcomes of BPPV in the long term. However, clinical trials with longer follow‐up periods are needed to unravel its efficacy.
Epley 手法是治疗良性阵发性位置性眩晕(BPPV)最有效的方法。倍他司汀已被证明能有效治疗 BPPV。本系统性综述旨在比较Epley手法联合倍他司汀与单纯Epley手法在减少BPPV残余眩晕方面的有效性。我们纳入了将Epley手法联合倍他司汀与单纯Epley手法治疗BPPV进行比较的随机对照试验(RCT)。我们使用眩晕障碍量表(DHI)、眩晕视觉模拟量表(VAS)和激惹手法评估了这种干预方法的有效性。我们对连续性结果采用标准化平均差(SMD),对二分法结果采用几率比(OR)。在DHI评分方面,与单独使用Epley手法相比,使用倍他司汀配合Epley手法没有临床显著性差异(SMD:-0.11,95%置信区间[CI],-0.57至0.34,P = 0.63,I2 = 79%)。63,I2 = 79%)、VAS 评分(SMD:-0.57,95% 置信区间 [CI],-1.57 至 0.43,p = 0.26,I2 = 89%)或激惹动作(OR:1.84,95% 置信区间 [CI],0.92 至 3.68,p = 0.08,I2 = 0%)。然而,接受倍他司汀与Epley手法联合治疗的患者在服用倍他司汀4周后,其VAS评分出现了统计学意义上的显著下降(SMD:-0.89,95% CI,-1.30至-0.49,p < 0.0001,I2 = 33%)。将倍他司汀与Epley手法结合使用可改善BPPV的长期疗效,但还需要进行更长时间的临床试验来揭示其疗效。
{"title":"Effectiveness of betahistine as an add‐on therapy to epley maneuver for benign paroxysmal positional vertigo: A systematic review and meta‐analysis","authors":"Renad M Alsolamy, Abdulaziz K. Alaraifi, Yazeed Aloqaili","doi":"10.1002/wjo2.161","DOIUrl":"https://doi.org/10.1002/wjo2.161","url":null,"abstract":"Epley maneuver is the most effective treatment for benign paroxysmal positional vertigo (BPPV). Betahistine has been shown to be effective in treating BPPV. This systematic review aims to compare the effectiveness of Epley maneuver with betahistine to Epley maneuver alone in reducing residual dizziness in BPPV.Medline, Embase, and CENTRAL.We included randomized controlled trials (RCTs) that compared Epley maneuver with betahistine to Epley maneuver alone for treating BPPV. We evaluated the effectiveness of this intervention using Dizziness Handicap Inventory (DHI), Visual Analog Scale (VAS) for vertigo, and provocation maneuvers. We used the standardized mean difference (SMD) for continuous outcomes and the odds ratio (OR) for the dichotomous outcomes.A total of eight RCTs that enrolled 516 participants were deemed eligible. Administration of betahistine with Epley maneuver showed no clinically significant difference over Epley maneuver alone in DHI score (SMD: −0.11, 95% confidence interval [CI], −0.57 to 0.34, p = 0.63, I2 = 79%), VAS scores (SMD: −0.57, 95% CI, −1.57 to 0.43, p = 0.26, I2 = 89%), or on provocation maneuvers (OR: 1.84, 95% CI, 0.92 to 3.68, p = 0.08, I2 = 0%) after 1 week of betahistine administration. However, participants who received betahistine combined with Epley maneuver showed a statistically significant reduction in VAS scores after 4 weeks of betahistine administration (SMD: −0.89, 95% CI, −1.30 to −0.49, p < 0.0001, I2 = 33%).Combining betahistine with Epley maneuver could improve the outcomes of BPPV in the long term. However, clinical trials with longer follow‐up periods are needed to unravel its efficacy.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"41 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140231531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoral microscopic‐assisted sialolithotomy for management of medium‐large submandibular sialolithiasis: A refined technique 口内显微镜辅助霰粒肿切开术治疗中大型颌下腺霰粒肿:改良技术
Pub Date : 2024-03-04 DOI: 10.1002/wjo2.153
Emad A. Magdy, Mahmoud Seif-Elnasr, Omneya Gamaleldin, Mohamed K. Taha, Mohamed F. Fathalla
Sialendoscopy has become the standard treatment for sialolithiasis; however, larger submandibular calculi may require an incisional technique. This study describes and evaluates an intraoral microscopic‐assisted sialolithotomy (IMAS) as a refined submandibular stone extraction technique.Retrospective case series of 64 submandibular IMAS procedures operated at a tertiary university center and private hospital from 2015 to 2021 were evaluated. Preoperative radiological assessment included noncontrast computed tomography scan ± magnetic resonance sialography. Stone characteristics (side, number, size, and location), operative findings, complications, and postoperative follow‐up were reviewed. Success was defined as successful intraoral stone extraction with no symptoms or stone recurrence for at least 12 months postoperatively.The study included 43 males and 19 females, mean age 38 ± 12 years. Two patients had bilateral stones. All but one operated gland had stones extracted (98.4%), however the true success was 93.8% (60/64) as three patients had recurrent/residual stones within a year. Biggest stone longest diameter was 9.8 ± 4.6 mm (range, 5–30 mm). Hilar and intraglandular stone locations were 73.4% and 6.3%, respectively. Median operative time was 55 min. Adjunctive sialendoscopy was performed in 42.2%. Its use is significantly correlated with having ˃3 stones (mean 3.4 vs. 1.2 stones) [P < 0.001, 95% confidence interval: −3.19 to −1.25]. Minor complications included temporary lingual paresthesia (7.8%) and postoperative ranula (1.6%).Submandibular IMAS is a highly effective safe technique for stones (≥5 mm). The improved microscopic visualization, illumination and magnification allows addressing all stone locations including intraglandular calculi and enables better lingual nerve identification and preservation.
霰粒肿内窥镜检查已成为治疗霰粒肿的标准方法;然而,较大的颌下结石可能需要采用切开技术。本研究描述并评估了口腔内显微镜辅助霰粒肿切开术(IMAS),将其作为一种改良的颌下结石取出技术。本研究评估了 2015 年至 2021 年在一所三级大学中心和私立医院进行的 64 例颌下 IMAS 手术的回顾性病例系列。术前放射学评估包括非对比计算机断层扫描和磁共振颌面造影。对结石特征(侧面、数量、大小和位置)、手术结果、并发症和术后随访进行了回顾。成功的定义是口内取石成功,术后至少12个月内无症状或结石复发。两名患者为双侧结石。除一名患者外,所有接受手术的腺体都取出了结石(98.4%),但真正的成功率为 93.8%(60/64),因为有三名患者在一年内复发/残留结石。最大结石的最长直径为 9.8 ± 4.6 毫米(范围为 5-30 毫米)。结石位于肝门和腺内的比例分别为73.4%和6.3%。手术时间中位数为55分钟。42.2%的患者进行了辅助巩膜内镜检查。内镜的使用与结石数量达到˃3(平均 3.4 颗对 1.2 颗)明显相关[P < 0.001,95% 置信区间:-3.19 到 -1.25] 。轻微并发症包括暂时性舌麻痹(7.8%)和术后匐茎(1.6%)。显微镜视野、照明和放大率的提高可解决包括腺内结石在内的所有结石位置,并能更好地识别和保护舌神经。
{"title":"Intraoral microscopic‐assisted sialolithotomy for management of medium‐large submandibular sialolithiasis: A refined technique","authors":"Emad A. Magdy, Mahmoud Seif-Elnasr, Omneya Gamaleldin, Mohamed K. Taha, Mohamed F. Fathalla","doi":"10.1002/wjo2.153","DOIUrl":"https://doi.org/10.1002/wjo2.153","url":null,"abstract":"Sialendoscopy has become the standard treatment for sialolithiasis; however, larger submandibular calculi may require an incisional technique. This study describes and evaluates an intraoral microscopic‐assisted sialolithotomy (IMAS) as a refined submandibular stone extraction technique.Retrospective case series of 64 submandibular IMAS procedures operated at a tertiary university center and private hospital from 2015 to 2021 were evaluated. Preoperative radiological assessment included noncontrast computed tomography scan ± magnetic resonance sialography. Stone characteristics (side, number, size, and location), operative findings, complications, and postoperative follow‐up were reviewed. Success was defined as successful intraoral stone extraction with no symptoms or stone recurrence for at least 12 months postoperatively.The study included 43 males and 19 females, mean age 38 ± 12 years. Two patients had bilateral stones. All but one operated gland had stones extracted (98.4%), however the true success was 93.8% (60/64) as three patients had recurrent/residual stones within a year. Biggest stone longest diameter was 9.8 ± 4.6 mm (range, 5–30 mm). Hilar and intraglandular stone locations were 73.4% and 6.3%, respectively. Median operative time was 55 min. Adjunctive sialendoscopy was performed in 42.2%. Its use is significantly correlated with having ˃3 stones (mean 3.4 vs. 1.2 stones) [P < 0.001, 95% confidence interval: −3.19 to −1.25]. Minor complications included temporary lingual paresthesia (7.8%) and postoperative ranula (1.6%).Submandibular IMAS is a highly effective safe technique for stones (≥5 mm). The improved microscopic visualization, illumination and magnification allows addressing all stone locations including intraglandular calculi and enables better lingual nerve identification and preservation.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"18 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140266165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Member List of the Second Editorial Board of World Journal of Otorhinolaryngology‐Head and Neck Surgery 世界耳鼻咽喉头颈外科杂志》第二届编辑委员会成员名单
Pub Date : 2024-03-01 DOI: 10.1002/wjo2.171
{"title":"Member List of the Second Editorial Board of World Journal of Otorhinolaryngology‐Head and Neck Surgery","authors":"","doi":"10.1002/wjo2.171","DOIUrl":"https://doi.org/10.1002/wjo2.171","url":null,"abstract":"","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"3 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140406656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of COVID‐19‐associated mucormycosis epidemic in India: A prospective 2‐year follow‐up study 印度与 COVID-19 相关的粘孢子菌病疫情的结果:为期两年的前瞻性跟踪研究
Pub Date : 2024-02-26 DOI: 10.1002/wjo2.162
Vishav Yadav, Sanjeev Bhagat, Khushboo Goel, R. Sibia, D. Sharma, T. Sidhu, Saivi Rajdev, Ankita Aggarwal
The objective of this study was to study the various outcomes among coronavirus disease 2019 (COVID‐19)‐associated mucormycosis (CAM) in terms of morbidity and mortality.A prospective study was done on 107 patients (60 male, 47 female) in the Department of Otolaryngology and Head and Neck Surgery, Government Medical College, Patiala, India, diagnosed with CAM from April 2021 to August 2021. The patients were managed both medically and surgically. The follow‐up was done up to 2 years to assess the various outcomes.Out of 107 patients, short‐term (3 months) survival was 68.22%, and long‐term (2 years) survival was 52.34%. Overall mortality was 47.66%, with short‐term mortality of 31.77% and long‐term mortality of 15.89%. Eye loss was seen in 17 patients, residual ophthalmoplegia in 12, palatal loss in 15, depression in 56, cerebrospinal fluid rhinorrhea in two, and recurrence in two patients.In conclusion, despite early management and successful initial outcome, the patients are still haunted by the after‐effects of CAM like residual morbidity in terms of eye and palate loss, ophthalmoplegia, and depression. Delayed mortality has also been noticed over 2 years of follow‐up.
本研究旨在研究2019年冠状病毒病(COVID-19)相关粘液瘤病(CAM)在发病率和死亡率方面的各种结果。本研究对印度帕蒂亚拉政府医学院耳鼻咽喉头颈外科的107名患者(60名男性,47名女性)进行了前瞻性研究,这些患者在2021年4月至2021年8月期间被诊断为CAM。患者均接受了药物和手术治疗。在 107 名患者中,短期(3 个月)存活率为 68.22%,长期(2 年)存活率为 52.34%。总死亡率为 47.66%,其中短期死亡率为 31.77%,长期死亡率为 15.89%。总之,尽管进行了早期治疗并取得了初步成功,但患者仍被 CAM 的后遗症所困扰,如眼部和腭部缺失、眼球震颤和抑郁等。在两年的随访中,还发现了延迟死亡率。
{"title":"Outcomes of COVID‐19‐associated mucormycosis epidemic in India: A prospective 2‐year follow‐up study","authors":"Vishav Yadav, Sanjeev Bhagat, Khushboo Goel, R. Sibia, D. Sharma, T. Sidhu, Saivi Rajdev, Ankita Aggarwal","doi":"10.1002/wjo2.162","DOIUrl":"https://doi.org/10.1002/wjo2.162","url":null,"abstract":"The objective of this study was to study the various outcomes among coronavirus disease 2019 (COVID‐19)‐associated mucormycosis (CAM) in terms of morbidity and mortality.A prospective study was done on 107 patients (60 male, 47 female) in the Department of Otolaryngology and Head and Neck Surgery, Government Medical College, Patiala, India, diagnosed with CAM from April 2021 to August 2021. The patients were managed both medically and surgically. The follow‐up was done up to 2 years to assess the various outcomes.Out of 107 patients, short‐term (3 months) survival was 68.22%, and long‐term (2 years) survival was 52.34%. Overall mortality was 47.66%, with short‐term mortality of 31.77% and long‐term mortality of 15.89%. Eye loss was seen in 17 patients, residual ophthalmoplegia in 12, palatal loss in 15, depression in 56, cerebrospinal fluid rhinorrhea in two, and recurrence in two patients.In conclusion, despite early management and successful initial outcome, the patients are still haunted by the after‐effects of CAM like residual morbidity in terms of eye and palate loss, ophthalmoplegia, and depression. Delayed mortality has also been noticed over 2 years of follow‐up.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In‐office serial intralesional steroid injection for subglottic stenosis: Case series of 14 patients with multiple etiologies 诊室内连续注射类固醇治疗声门下狭窄:14 位多种病因患者的病例系列
Pub Date : 2024-02-08 DOI: 10.1002/wjo2.159
Nader Wehbi, Claire Gleadhill, David Ahmadian, Jonathan R. Skirko, Helena T. Yip
Subglottic stenosis (SGS) is commonly treated with endoscopic dilations or tracheal resection. Since office‐based serial intralesional steroid injections (SILSI) were first reported in 2017, they have been established as an effective, less invasive treatment alternative or adjunct. The aim of this study is to add to the literature investigating the efficacy of office‐based SILSIs for idiopathic and post‐intubation SGS patients, specifically studying surgery‐free intervals (SFIs) and discussing our experience with SILSI treatment order and stenosis grade.This study is a retrospective case series of 14 patients with subglottic stenosis treated with in‐office serial intralesional steroid injections as a primary or adjuvant treatment from 2018 to 2022 in an academic tertiary care center.Of seven patients with calculable SFI, a mean SFI increase of 481.28 days was observed following SILSI treatment (p = 0.042). Ten patients in our cohort presented with idiopathic or post‐intubation grade 2 SGS and were managed successfully with a combination of endoscopic dilation and SILSI. Two patients with post‐intubation grade 1 SGS were managed successfully with SILSI as their primary treatment. Two patients with post‐intubation grade 3 SGS required a tracheal resection and did not benefit from SILSI.We have found that SFI significantly increased following SILSI initiation. Although statistical power was limited given the small sample size, our findings suggest that SILSI may be an effective primary treatment in low‐grade stenosis. SILSI as an adjuvant to endoscopic dilation may be most effective in intermediate‐grade stenosis. SILSI may not be effective in high‐grade stenosis patients who failed prior endoscopic treatment.
声门下狭窄(SGS)通常采用内窥镜扩张术或气管切除术进行治疗。自 2017 年首次报道基于诊室的连续腔内类固醇注射(SILSI)以来,它已被确定为一种有效的、创伤较小的治疗替代方法或辅助方法。本研究旨在补充研究基于诊室的 SILSI 对特发性和插管后 SGS 患者疗效的文献,特别是研究无手术间隔期(SFIs),并讨论我们在 SILSI 治疗顺序和狭窄等级方面的经验。本研究是一项回顾性病例系列研究,研究对象是2018年至2022年在一家学术性三级医疗中心接受诊室内连续注射类固醇作为主要或辅助治疗的14例声门下狭窄患者。在7例可计算SFI的患者中,观察到SILSI治疗后平均SFI增加了481.28天(P = 0.042)。在我们的队列中,有 10 名患者属于特发性或插管后 2 级 SGS,他们在接受内窥镜扩张术和 SILSI 联合治疗后获得了成功。两名插管后 1 级 SGS 患者采用 SILSI 作为主要治疗方法,并获得成功。两名插管后 3 级 SGS 患者需要进行气管切除术,但并未从 SILSI 中获益。虽然由于样本量较小,统计能力有限,但我们的研究结果表明,SILSI 可能是治疗低级别气管狭窄的有效方法。SILSI 作为内窥镜扩张术的辅助手段,可能对中级狭窄最有效。SILSI 可能对之前内窥镜治疗失败的高级别狭窄患者无效。
{"title":"In‐office serial intralesional steroid injection for subglottic stenosis: Case series of 14 patients with multiple etiologies","authors":"Nader Wehbi, Claire Gleadhill, David Ahmadian, Jonathan R. Skirko, Helena T. Yip","doi":"10.1002/wjo2.159","DOIUrl":"https://doi.org/10.1002/wjo2.159","url":null,"abstract":"Subglottic stenosis (SGS) is commonly treated with endoscopic dilations or tracheal resection. Since office‐based serial intralesional steroid injections (SILSI) were first reported in 2017, they have been established as an effective, less invasive treatment alternative or adjunct. The aim of this study is to add to the literature investigating the efficacy of office‐based SILSIs for idiopathic and post‐intubation SGS patients, specifically studying surgery‐free intervals (SFIs) and discussing our experience with SILSI treatment order and stenosis grade.This study is a retrospective case series of 14 patients with subglottic stenosis treated with in‐office serial intralesional steroid injections as a primary or adjuvant treatment from 2018 to 2022 in an academic tertiary care center.Of seven patients with calculable SFI, a mean SFI increase of 481.28 days was observed following SILSI treatment (p = 0.042). Ten patients in our cohort presented with idiopathic or post‐intubation grade 2 SGS and were managed successfully with a combination of endoscopic dilation and SILSI. Two patients with post‐intubation grade 1 SGS were managed successfully with SILSI as their primary treatment. Two patients with post‐intubation grade 3 SGS required a tracheal resection and did not benefit from SILSI.We have found that SFI significantly increased following SILSI initiation. Although statistical power was limited given the small sample size, our findings suggest that SILSI may be an effective primary treatment in low‐grade stenosis. SILSI as an adjuvant to endoscopic dilation may be most effective in intermediate‐grade stenosis. SILSI may not be effective in high‐grade stenosis patients who failed prior endoscopic treatment.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"305 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In‐office serial intralesional steroid injection for subglottic stenosis: Case series of 14 patients with multiple etiologies 诊室内连续注射类固醇治疗声门下狭窄:14 位多种病因患者的病例系列
Pub Date : 2024-02-08 DOI: 10.1002/wjo2.159
Nader Wehbi, Claire Gleadhill, David Ahmadian, Jonathan R. Skirko, Helena T. Yip
Subglottic stenosis (SGS) is commonly treated with endoscopic dilations or tracheal resection. Since office‐based serial intralesional steroid injections (SILSI) were first reported in 2017, they have been established as an effective, less invasive treatment alternative or adjunct. The aim of this study is to add to the literature investigating the efficacy of office‐based SILSIs for idiopathic and post‐intubation SGS patients, specifically studying surgery‐free intervals (SFIs) and discussing our experience with SILSI treatment order and stenosis grade.This study is a retrospective case series of 14 patients with subglottic stenosis treated with in‐office serial intralesional steroid injections as a primary or adjuvant treatment from 2018 to 2022 in an academic tertiary care center.Of seven patients with calculable SFI, a mean SFI increase of 481.28 days was observed following SILSI treatment (p = 0.042). Ten patients in our cohort presented with idiopathic or post‐intubation grade 2 SGS and were managed successfully with a combination of endoscopic dilation and SILSI. Two patients with post‐intubation grade 1 SGS were managed successfully with SILSI as their primary treatment. Two patients with post‐intubation grade 3 SGS required a tracheal resection and did not benefit from SILSI.We have found that SFI significantly increased following SILSI initiation. Although statistical power was limited given the small sample size, our findings suggest that SILSI may be an effective primary treatment in low‐grade stenosis. SILSI as an adjuvant to endoscopic dilation may be most effective in intermediate‐grade stenosis. SILSI may not be effective in high‐grade stenosis patients who failed prior endoscopic treatment.
声门下狭窄(SGS)通常采用内窥镜扩张术或气管切除术进行治疗。自 2017 年首次报道基于诊室的连续腔内类固醇注射(SILSI)以来,它已被确定为一种有效的、创伤较小的治疗替代方法或辅助方法。本研究旨在补充研究基于诊室的 SILSI 对特发性和插管后 SGS 患者疗效的文献,特别是研究无手术间隔期(SFIs),并讨论我们在 SILSI 治疗顺序和狭窄等级方面的经验。本研究是一项回顾性病例系列研究,研究对象是2018年至2022年在一家学术性三级医疗中心接受诊室内连续注射类固醇作为主要或辅助治疗的14例声门下狭窄患者。在7例可计算SFI的患者中,观察到SILSI治疗后平均SFI增加了481.28天(P = 0.042)。在我们的队列中,有 10 名患者属于特发性或插管后 2 级 SGS,他们在接受内窥镜扩张术和 SILSI 联合治疗后获得了成功。两名插管后 1 级 SGS 患者采用 SILSI 作为主要治疗方法,并获得成功。两名插管后 3 级 SGS 患者需要进行气管切除术,但并未从 SILSI 中获益。虽然由于样本量较小,统计能力有限,但我们的研究结果表明,SILSI 可能是治疗低级别气管狭窄的有效方法。SILSI 作为内窥镜扩张术的辅助手段,可能对中级狭窄最有效。SILSI 可能对之前内窥镜治疗失败的高级别狭窄患者无效。
{"title":"In‐office serial intralesional steroid injection for subglottic stenosis: Case series of 14 patients with multiple etiologies","authors":"Nader Wehbi, Claire Gleadhill, David Ahmadian, Jonathan R. Skirko, Helena T. Yip","doi":"10.1002/wjo2.159","DOIUrl":"https://doi.org/10.1002/wjo2.159","url":null,"abstract":"Subglottic stenosis (SGS) is commonly treated with endoscopic dilations or tracheal resection. Since office‐based serial intralesional steroid injections (SILSI) were first reported in 2017, they have been established as an effective, less invasive treatment alternative or adjunct. The aim of this study is to add to the literature investigating the efficacy of office‐based SILSIs for idiopathic and post‐intubation SGS patients, specifically studying surgery‐free intervals (SFIs) and discussing our experience with SILSI treatment order and stenosis grade.This study is a retrospective case series of 14 patients with subglottic stenosis treated with in‐office serial intralesional steroid injections as a primary or adjuvant treatment from 2018 to 2022 in an academic tertiary care center.Of seven patients with calculable SFI, a mean SFI increase of 481.28 days was observed following SILSI treatment (p = 0.042). Ten patients in our cohort presented with idiopathic or post‐intubation grade 2 SGS and were managed successfully with a combination of endoscopic dilation and SILSI. Two patients with post‐intubation grade 1 SGS were managed successfully with SILSI as their primary treatment. Two patients with post‐intubation grade 3 SGS required a tracheal resection and did not benefit from SILSI.We have found that SFI significantly increased following SILSI initiation. Although statistical power was limited given the small sample size, our findings suggest that SILSI may be an effective primary treatment in low‐grade stenosis. SILSI as an adjuvant to endoscopic dilation may be most effective in intermediate‐grade stenosis. SILSI may not be effective in high‐grade stenosis patients who failed prior endoscopic treatment.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":" 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139792524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Historical milestones in the evolution of the procedure of neck dissection 颈部解剖程序演变的历史里程碑
Pub Date : 2024-02-06 DOI: 10.1002/wjo2.152
K. Devaraja
Although neck dissection has evolved to become an integral part of the surgical armamentarium for managing head and neck cancers, the manner in which the procedure has reached its present state is worth revisiting.Published original articles, reviews, clinical practice guidelines, and consensus statements related to the basis, indication, and classification of the neck dissection.This review discusses some of the critical milestones before and after the description of the procedure of neck dissection by George Crile Sr. in 1905, which eventually played a role in the evolution of this commonly performed oncosurgical procedure.Several large observational studies of the twentieth century and multicentric randomized trials at the turn of the twenty‐first century have shaped neck dissection into a safe and reliable oncosurgical procedure.From being a radical surgery that was done mostly in large nodal diseases for curative or palliative purposes to becoming a simple procedure that is carried out even in node‐negative cases of head and neck cancers for prognostic purposes, the procedure of neck dissection has come a long way and continues to evolve.
尽管颈部切除术已发展成为治疗头颈部癌症的外科手术中不可或缺的一部分,但该手术是如何发展到今天的,值得我们重新审视。本综述讨论了老乔治-克里尔(George Crile Sr.)于1905年描述颈部切除术前后的一些重要里程碑,这些里程碑最终在这一常见的外科手术的发展过程中发挥了作用。从最初主要针对大结节疾病进行根治性或姑息性手术,到现在即使是结节阴性的头颈部癌症病例也可进行以预后为目的的简单手术,颈部离断术已经走过了漫长的道路,并在继续发展。
{"title":"Historical milestones in the evolution of the procedure of neck dissection","authors":"K. Devaraja","doi":"10.1002/wjo2.152","DOIUrl":"https://doi.org/10.1002/wjo2.152","url":null,"abstract":"Although neck dissection has evolved to become an integral part of the surgical armamentarium for managing head and neck cancers, the manner in which the procedure has reached its present state is worth revisiting.Published original articles, reviews, clinical practice guidelines, and consensus statements related to the basis, indication, and classification of the neck dissection.This review discusses some of the critical milestones before and after the description of the procedure of neck dissection by George Crile Sr. in 1905, which eventually played a role in the evolution of this commonly performed oncosurgical procedure.Several large observational studies of the twentieth century and multicentric randomized trials at the turn of the twenty‐first century have shaped neck dissection into a safe and reliable oncosurgical procedure.From being a radical surgery that was done mostly in large nodal diseases for curative or palliative purposes to becoming a simple procedure that is carried out even in node‐negative cases of head and neck cancers for prognostic purposes, the procedure of neck dissection has come a long way and continues to evolve.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"97 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139802153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Historical milestones in the evolution of the procedure of neck dissection 颈部解剖程序演变的历史里程碑
Pub Date : 2024-02-06 DOI: 10.1002/wjo2.152
K. Devaraja
Although neck dissection has evolved to become an integral part of the surgical armamentarium for managing head and neck cancers, the manner in which the procedure has reached its present state is worth revisiting.Published original articles, reviews, clinical practice guidelines, and consensus statements related to the basis, indication, and classification of the neck dissection.This review discusses some of the critical milestones before and after the description of the procedure of neck dissection by George Crile Sr. in 1905, which eventually played a role in the evolution of this commonly performed oncosurgical procedure.Several large observational studies of the twentieth century and multicentric randomized trials at the turn of the twenty‐first century have shaped neck dissection into a safe and reliable oncosurgical procedure.From being a radical surgery that was done mostly in large nodal diseases for curative or palliative purposes to becoming a simple procedure that is carried out even in node‐negative cases of head and neck cancers for prognostic purposes, the procedure of neck dissection has come a long way and continues to evolve.
尽管颈部切除术已发展成为治疗头颈部癌症的外科手术中不可或缺的一部分,但该手术是如何发展到今天的,值得我们重新审视。本综述讨论了老乔治-克里尔(George Crile Sr.)于1905年描述颈部切除术前后的一些重要里程碑,这些里程碑最终在这一常见的外科手术的发展过程中发挥了作用。从最初主要针对大结节疾病进行根治性或姑息性手术,到现在即使是结节阴性的头颈部癌症病例也可进行以预后为目的的简单手术,颈部离断术已经走过了漫长的道路,并在继续发展。
{"title":"Historical milestones in the evolution of the procedure of neck dissection","authors":"K. Devaraja","doi":"10.1002/wjo2.152","DOIUrl":"https://doi.org/10.1002/wjo2.152","url":null,"abstract":"Although neck dissection has evolved to become an integral part of the surgical armamentarium for managing head and neck cancers, the manner in which the procedure has reached its present state is worth revisiting.Published original articles, reviews, clinical practice guidelines, and consensus statements related to the basis, indication, and classification of the neck dissection.This review discusses some of the critical milestones before and after the description of the procedure of neck dissection by George Crile Sr. in 1905, which eventually played a role in the evolution of this commonly performed oncosurgical procedure.Several large observational studies of the twentieth century and multicentric randomized trials at the turn of the twenty‐first century have shaped neck dissection into a safe and reliable oncosurgical procedure.From being a radical surgery that was done mostly in large nodal diseases for curative or palliative purposes to becoming a simple procedure that is carried out even in node‐negative cases of head and neck cancers for prognostic purposes, the procedure of neck dissection has come a long way and continues to evolve.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139862197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Venous vascular malformation of the parotid gland 腮腺静脉血管畸形
Pub Date : 2024-02-05 DOI: 10.1002/wjo2.160
Amir A. Hakimi, Eric L. Wu, Jonathan Giurintano
Venous vascular malformations of the parotid gland are very rare vascular tumors, especially among adults. This case report discusses the presentation and challenges of diagnosing a venous vascular malformation of the parotid gland in a patient with previous oncologic history. Our patient is a 45‐year‐old female with a history of breast cancer, meningioma, and secreting pituitary adenoma who presented with a malformation on magnetic resonance imaging, incidentally demonstrating a T2 intense mass in the superficial lobe of the right parotid gland. She was otherwise asymptomatic. Ultrasound‐guided fine needle aspiration was nondiagnostic. She underwent a right inferior superficial parotidectomy. Histologic section analysis demonstrated a well‐delineated vascular tumor made of large vascular spaces with thin walls surrounded by a parotid tissue consistent with a venous vascular malformation of the parotid gland. Venous vascular malformations are exceedingly rare, especially among adults. Ultrasound‐guided fine needle aspiration can be of limited value. Parotidectomy may be electively considered for diagnostic and therapeutic purposes.
腮腺静脉血管畸形是一种非常罕见的血管肿瘤,尤其是在成人中。本病例报告讨论了一名既往有肿瘤病史的患者腮腺静脉血管畸形的表现和诊断难题。我们的患者是一名 45 岁女性,曾患乳腺癌、脑膜瘤和分泌型垂体腺瘤,磁共振成像显示右侧腮腺浅叶有一个 T2 强肿块。她没有其他症状。超声引导下的细针穿刺无法确诊。她接受了右侧腮腺下浅叶切除术。组织学切片分析显示,腮腺静脉血管畸形是一种界限清晰的血管瘤,由壁薄的大血管间隙组成,周围为腮腺组织。静脉血管畸形极为罕见,尤其是在成人中。超声引导下细针穿刺的价值有限。出于诊断和治疗目的,可选择腮腺切除术。
{"title":"Venous vascular malformation of the parotid gland","authors":"Amir A. Hakimi, Eric L. Wu, Jonathan Giurintano","doi":"10.1002/wjo2.160","DOIUrl":"https://doi.org/10.1002/wjo2.160","url":null,"abstract":"Venous vascular malformations of the parotid gland are very rare vascular tumors, especially among adults. This case report discusses the presentation and challenges of diagnosing a venous vascular malformation of the parotid gland in a patient with previous oncologic history. Our patient is a 45‐year‐old female with a history of breast cancer, meningioma, and secreting pituitary adenoma who presented with a malformation on magnetic resonance imaging, incidentally demonstrating a T2 intense mass in the superficial lobe of the right parotid gland. She was otherwise asymptomatic. Ultrasound‐guided fine needle aspiration was nondiagnostic. She underwent a right inferior superficial parotidectomy. Histologic section analysis demonstrated a well‐delineated vascular tumor made of large vascular spaces with thin walls surrounded by a parotid tissue consistent with a venous vascular malformation of the parotid gland. Venous vascular malformations are exceedingly rare, especially among adults. Ultrasound‐guided fine needle aspiration can be of limited value. Parotidectomy may be electively considered for diagnostic and therapeutic purposes.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"45 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139865242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
World Journal of Otorhinolaryngology - Head and Neck Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1