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Age- and Sex-Specific Incidence Trends of Eating Disorders in South Korea: Insights From a Decade of National Health Insurance Data (2012-2021). 韩国饮食失调的年龄和性别发病率趋势:来自十年国民健康保险数据(2012-2021)的见解。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-02-08 DOI: 10.1002/eat.70052
Hye Soo Kim, Kyeong-A Yang, Hyemin Cho, Su Hwan Kim, Soon-Beom Hong

Objective: Research on the incidence trends of eating disorders remains limited in Asia. This study aims to analyze the annual incidence rates and incident case characteristics in the Korean general population.

Method: The National Health Insurance Service database was used to examine the incidence rates of eating disorders from 2012 to 2021. A total of 34,615 patients with incident eating disorders aged 0-49 years were analyzed. Comorbidity and medication analyses used a 2013-2020 subset. Linear regression analyses and Mann-Kendall trend tests were conducted to examine temporal trends across age and sex. Chi-square and Wilcoxon rank-sum tests were applied for epidemiological and clinical characteristics of the 0-19 and ≥ 20 age groups.

Results: Adults' annual incidence rates increased over the study period (τ = 0.689, p = 0.007). The 20-24 age group had the highest incidence (16.75-38.38 per 100,000 person-years). Individuals aged 0-19 years showed a stable incidence rate (τ = 0.244, p = 0.371), although males aged 0-19 years demonstrated a decreasing trend (B = -0.272, SE = 0.091, p = 0.018, 95% CI = [-0.483, -0.061]). Mood and anxiety disorders were the most frequent comorbidities. The 0-19 age group more frequently utilized tertiary healthcare institutions. Antidepressants were prescribed more frequently than antipsychotics. Fluoxetine and aripiprazole were the most common antidepressant and antipsychotic, respectively.

Discussion: The findings show distinct age- and sex-specific patterns in eating disorder incidence, underscoring the need for a tailored approach. Worldwide differences may offer etiological insights. A limitation is the aggregation of eating disorder subtypes.

目的:对亚洲饮食失调发病率趋势的研究仍然有限。本研究旨在分析韩国普通人群的年发病率和病例特征。方法:采用国民健康保险服务数据库对2012 - 2021年饮食失调的发病率进行调查。本研究共分析了34,615例0 ~ 49岁的突发饮食失调患者。合并症和药物分析使用了2013-2020年的子集。采用线性回归分析和Mann-Kendall趋势检验来检验不同年龄和性别的时间趋势。0-19岁和≥20岁年龄组的流行病学和临床特征采用卡方和Wilcoxon秩和检验。结果:成年人的年发病率在研究期间增加(τ = 0.689, p = 0.007)。20-24岁年龄组发病率最高(16.75-38.38 / 10万人年)。0 ~ 19岁个体发病率稳定(τ = 0.244, p = 0.371), 0 ~ 19岁男性发病率呈下降趋势(B = -0.272, SE = 0.091, p = 0.018, 95% CI =[-0.483, -0.061])。情绪和焦虑障碍是最常见的合并症。0-19岁年龄组更多地利用三级保健机构。抗抑郁药比抗精神病药开得更频繁。氟西汀和阿立哌唑分别是最常见的抗抑郁药和抗精神病药。讨论:研究结果显示饮食失调的发病率有明显的年龄和性别差异,强调需要量身定制的方法。世界范围内的差异可能提供病因学上的见解。一个限制是饮食失调亚型的聚集。
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引用次数: 0
A Program-Led Motivational App (MI-Coach: ED) for Eating Disorder Waitlists: Findings From a Feasibility and Acceptability Pilot Trial. 一个项目主导的激励应用程序(MI-Coach: ED)进食障碍候补名单:从可行性和可接受性试点试验的结果。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-02-06 DOI: 10.1002/eat.70053
Amané Halicki-Asakawa, Emily Fuller, Maya Libben

Objective: Individuals with eating disorders (EDs) often face significant barriers to accessing care, including prolonged waitlists and systemic delays. Digital interventions, such as mobile apps, offer a scalable way to enhance pre-treatment engagement during this high-risk period. This pilot study evaluated the feasibility and acceptability of MI-Coach: ED, a program-led mobile app designed to support motivation among female-identifying individuals awaiting ED treatment.

Method: Twenty-three female-identifying individuals on waitlists at ED clinics across British Columbia, Canada, participated in a 4-week single-arm pilot trial of MI-Coach: ED. The app delivered motivational interviewing-informed content through seven sequential modules containing reflective exercises, psychoeducational articles, and psychologist-led videos. Feasibility was assessed via service-provider uptake, participant enrollment, engagement, and retention metrics. Acceptability was measured using the user version of the Mobile App Rating Scale and adapted Technology Acceptance Model ratings. Exploratory analyses descriptively examined pre-to-post changes in motivation and related symptoms.

Results: Feasibility was constrained at the service-provider level, with 6% of contacted sites agreeing to distribute study materials. At the participant level, 67.6% initiated app use and 44% completed at least four modules, and 78% completed pre- and post-assessments, indicating partial engagement across the sample. Participants rated the app positively across domains of quality, ease of use, and perceived usefulness. Small-to-medium reductions in global ED severity and depressive symptoms, as well as increases in motivational confidence, were observed with confidence intervals that did not cross zero. Change scores were moderately correlated across select motivational and symptom measures.

Discussion: Findings suggest that MI-Coach: ED was acceptable among users who engaged, while feasibility was substantially influenced by system-level recruitment constraints and variable participant engagement. Observed engagement patterns were lower than those reported for general mental health apps but consistent with prior digital ED intervention literature, underscoring the importance of disorder-specific feasibility benchmarks. Results will inform ongoing refinements and implementation strategies for a future randomized trial.

目的:患有饮食失调症(EDs)的个体通常面临着获得护理的重大障碍,包括长时间的等待名单和系统性延误。数字干预措施,如移动应用程序,提供了一种可扩展的方式来加强这一高风险时期的治疗前参与。这项试点研究评估了MI-Coach: ED的可行性和可接受性,这是一款以项目为主导的移动应用程序,旨在支持等待ED治疗的女性患者的动力。方法:在加拿大不列颠哥伦比亚省ED诊所的候诊名单上,有23名女性参与了为期四周的MI-Coach: ED单臂试点试验。该应用程序通过七个连续的模块提供动机性访谈信息,包括反思练习、心理教育文章和心理学家主导的视频。可行性通过服务提供者的吸收、参与者登记、参与和保留指标进行评估。可接受性是使用用户版本的移动应用评级量表和适应的技术接受模型评级来衡量的。探索性分析描述性地检查了前后动机和相关症状的变化。结果:可行性在服务提供者层面受到限制,只有6%的联系站点同意分发研究材料。在参与者层面,67.6%的人开始使用应用,44%的人完成了至少四个模块,78%的人完成了前后评估,这表明样本中存在部分参与度。参与者在质量、易用性和感知有用性方面对这款应用进行了积极评价。总体ED严重程度和抑郁症状的小到中等程度的减轻,以及动机信心的增加,观察到置信区间不超过零。改变得分在选择的动机和症状测量中具有中等相关性。讨论:研究结果表明,MI-Coach: ED在参与的用户中是可以接受的,而可行性则受到系统级招聘约束和可变参与者参与的重大影响。观察到的参与模式低于一般心理健康应用程序的报告,但与之前的数字ED干预文献一致,强调了特定障碍可行性基准的重要性。结果将为未来随机试验的持续改进和实施策略提供信息。
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引用次数: 0
Patterns of Uptake, Engagement, and Attrition in Randomized Controlled Trials of Digital Interventions for Eating Disorders: A Systematic Review and Meta-Analysis. 数字干预饮食失调的随机对照试验中的吸收、参与和消耗模式:系统回顾和荟萃分析。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-02-06 DOI: 10.1002/eat.70046
Claudia Liu, Cleo Anderson, Mariel Messer, Zoe McClure, Jake Linardon

Objective: This review aimed to quantify rates of uptake (treatment initiation), adherence (program completion), and attrition (study dropout) in randomized trials of digital eating disorder (ED) interventions, and to synthesize engagement reporting practices, their consistency, and associations with clinical outcomes.

Methods: Randomized trials of digital interventions (web, app, computerized, chatbots, etc.) delivered to people with diagnostic, subthreshold, or self-reported EDs were included. Random-effects meta-analyses were conducted to compute absolute rates of uptake, adherence, and attrition, while a narrative synthesis summarized engagement patterns and reporting.

Results: Forty-eight trials were included. The weighted mean uptake rate from 44 intervention conditions was 89.7% (95% PI = 67.0-97.0) and the weighted mean adherence rate from 14 intervention conditions was 41.8% (95% PI = 0.9-83.3). These estimates remained similar in a series of sensitivity analyses that adjusted for biases, outliers, and when limiting to specific clinical population groups. The weighted trial attrition rate was 23.3% (95% PI = 0.8-54.4); for intervention arms specificially it was 29.7% (95% PI = 9.7-62.3) and for waitlist arms it was 18.7% (95% PI = 4.6-52.3). Attrition was lower in trials that had human-participant interaction, offered therapeutic guidance, provided monetary reimbursement, tested a web/computer program (compared to a smartphone application), and had a longer follow-up (> 6 weeks). Reporting of engagement was inconsistent and heterogeneous, with nearly 90 different metrics recorded across trials. There was some evidence linking sustained user engagement to greater clinical benefit.

Conclusion: Findings offer practical benchmarks to inform future trial planning and highlight design elements that could be leveraged to enhance user engagement and retention.

目的:本综述旨在量化数字饮食失调(ED)干预的随机试验中的接受率(治疗开始)、依从性(项目完成)和损耗率(研究退出),并综合参与报告实践、其一致性以及与临床结果的关联。方法:纳入对诊断性、亚阈值性或自我报告性急症患者进行的数字干预(网络、应用程序、计算机化、聊天机器人等)的随机试验。随机效应荟萃分析用于计算绝对吸收率、依从性和流失率,而叙述性综合则总结了参与模式和报告。结果:纳入48项试验。44个干预条件的加权平均吸收率为89.7% (95% PI = 67.0 ~ 97.0), 14个干预条件的加权平均依从率为41.8% (95% PI = 0.9 ~ 83.3)。在一系列敏感性分析中,这些估计值在调整偏倚、异常值和限制特定临床人群时保持相似。加权试验损耗率为23.3% (95% PI = 0.8 ~ 54.4);干预组为29.7% (95% PI = 9.7-62.3),等待组为18.7% (95% PI = 4.6-52.3)。在有人类参与者互动、提供治疗指导、提供金钱补偿、测试网络/计算机程序(与智能手机应用程序相比)、随访时间较长(6周左右)的试验中,损耗较低。参与的报告是不一致的和异质的,在整个试验中记录了近90种不同的指标。有一些证据表明,持续的用户粘性与更大的临床效益有关。结论:调查结果为未来的试验计划提供了实用基准,并突出了可用于提高用户粘性和留存率的设计元素。
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引用次数: 0
When Medically Required Food Avoidance Goes Awry: A Conceptual Framework of ARFID as an Underrecognized Clinical Complication of Food Allergy. 当医学上需要的食物避免出错:ARFID作为食物过敏未被充分认识的临床并发症的概念框架。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-02-06 DOI: 10.1002/eat.70049
Kaitlin B Proctor, Brian P Vickery, William G Sharp

Pediatric patients with medical/developmental conditions face increased risk for avoidant/restrictive food intake disorder (ARFID). Diet-managed chronic illnesses may heighten risk for disordered eating, with emerging research finding medical symptoms predating disordered eating behaviors. Pediatric-onset immunoglobulin E-mediated food allergy ("food allergy") is on the rise, affecting an astonishing 8% of US children. The relationship between food allergy and ARFID is puzzlingly understudied despite food allergy clearly altering the individual's relationship with food, posing continuous danger, and requiring persistent, fundamental eating changes to maintain safety. Food allergy is managed through strict dietary avoidance of allergen(s) and confers well-documented risk to psychosocial functioning. Dietary restriction exceeding medically required avoidance (as observed in ARFID) further compounds risk for adverse health and psychosocial impacts. In this Spotlight, our team of clinical researchers working at the intersection of ARFID and food allergy proposes a model identifying three areas of food allergy-specific impact that may drive the higher prevalence of ARFID within this population. Failure to successfully regulate these universal drivers to preserve daily functioning may precipitate the development of ARFID. We propose (1) unique characteristics of allergic reactions and medical treatment, (2) the impacts of chronic vigilance and avoidance, and (3) response to learning paradigms and physiological upregulation disrupt the development of feeding/eating for both patients and caregivers. Patients with food allergy + ARFID may also be especially vulnerable to iatrogenic harm from the imprecision of current allergy testing modalities. We outline the sparse literature on food allergy + ARFID comorbidity and call for ARFID-focused research in this area.

患有医学/发育疾病的儿科患者面临回避/限制性食物摄入障碍(ARFID)的风险增加。饮食管理的慢性病可能会增加饮食失调的风险,新研究发现,在饮食失调行为之前,医学症状就会出现。儿童发病的免疫球蛋白e介导的食物过敏(“食物过敏”)正在上升,影响了8%的美国儿童。令人困惑的是,食物过敏和ARFID之间的关系还没有得到充分的研究,尽管食物过敏明显改变了个体与食物的关系,构成了持续的危险,需要持续的、基本的饮食改变来保持安全。食物过敏是通过严格避免饮食中的过敏原来控制的,有充分证据表明,食物过敏会给社会心理功能带来风险。饮食限制超过医学上要求的避免(如ARFID所观察到的)进一步加剧了不良健康和心理社会影响的风险。在本期重点报道中,我们的临床研究团队在ARFID和食物过敏的交叉领域工作,提出了一个模型,确定了食物过敏特异性影响的三个领域,这些领域可能会导致ARFID在该人群中更高的患病率。未能成功调节这些通用驱动因素以维持日常功能可能会加速ARFID的发展。我们提出(1)过敏反应和药物治疗的独特特征,(2)慢性警惕和回避的影响,以及(3)对学习范式的反应和生理上调扰乱了患者和照顾者的喂养/进食发展。食物过敏+ ARFID患者也可能特别容易受到目前过敏测试方式不精确的医源性伤害。我们概述了关于食物过敏+ ARFID合并症的稀疏文献,并呼吁在该领域开展以ARFID为重点的研究。
{"title":"When Medically Required Food Avoidance Goes Awry: A Conceptual Framework of ARFID as an Underrecognized Clinical Complication of Food Allergy.","authors":"Kaitlin B Proctor, Brian P Vickery, William G Sharp","doi":"10.1002/eat.70049","DOIUrl":"https://doi.org/10.1002/eat.70049","url":null,"abstract":"<p><p>Pediatric patients with medical/developmental conditions face increased risk for avoidant/restrictive food intake disorder (ARFID). Diet-managed chronic illnesses may heighten risk for disordered eating, with emerging research finding medical symptoms predating disordered eating behaviors. Pediatric-onset immunoglobulin E-mediated food allergy (\"food allergy\") is on the rise, affecting an astonishing 8% of US children. The relationship between food allergy and ARFID is puzzlingly understudied despite food allergy clearly altering the individual's relationship with food, posing continuous danger, and requiring persistent, fundamental eating changes to maintain safety. Food allergy is managed through strict dietary avoidance of allergen(s) and confers well-documented risk to psychosocial functioning. Dietary restriction exceeding medically required avoidance (as observed in ARFID) further compounds risk for adverse health and psychosocial impacts. In this Spotlight, our team of clinical researchers working at the intersection of ARFID and food allergy proposes a model identifying three areas of food allergy-specific impact that may drive the higher prevalence of ARFID within this population. Failure to successfully regulate these universal drivers to preserve daily functioning may precipitate the development of ARFID. We propose (1) unique characteristics of allergic reactions and medical treatment, (2) the impacts of chronic vigilance and avoidance, and (3) response to learning paradigms and physiological upregulation disrupt the development of feeding/eating for both patients and caregivers. Patients with food allergy + ARFID may also be especially vulnerable to iatrogenic harm from the imprecision of current allergy testing modalities. We outline the sparse literature on food allergy + ARFID comorbidity and call for ARFID-focused research in this area.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multivariate Trajectories of Eating Disorder Symptoms and Weight Status in 10- to 17-Year-Old Children and Adolescents. 10- 17岁儿童和青少年饮食失调症状和体重状况的多变量轨迹
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-02-06 DOI: 10.1002/eat.70045
Anja Hilbert, Danielle Schewe, Andreas Hiemisch, Antje Körner, Wieland Kiess, Ricarda Schmidt

Objective: Eating disorders (EDs) often emerge in adolescence, but developmental trajectories across different core features remain largely unclear.

Method: The prospective, community-based study included N = 898 participants aged 9.5-17.5 years (47.6% female, age 11.8 ± 1.4 years) with annual follow-up over 2-6 (3.4 ± 1.2) years. Multivariate trajectories of binge eating, restraint, weight-compensatory behaviors (Eating Disorder Examination-Questionnaire for Children), and body mass index-standard deviation score (BMI-SDS) derived from objective anthropometrics were analyzed using group-based multi-trajectory modeling (GBMTM) separately for girls and boys. ED and general psychopathology were used for validation and outcome comparisons.

Results: GBMTM identified five distinct trajectories of ED symptoms and BMI-SDS in girls and six in boys. Low-symptom trajectories at lower, normal, and higher BMI-SDS were most common and showed only mild, transient ED symptoms. In boys, trajectories were largely characterized by stable ED symptoms at different BMI-SDS levels, whereas in girls, ED symptoms showed more pronounced change over time. In both sexes, two high-risk subgroups reflected bulimic and binge-eating patterns and followed trajectories with elevated or increasing ED symptoms across ages, which in girls were particularly associated with increased ED and general psychopathology at last assessment.

Discussion: GBMTM results support the developmental specificity of bulimic/binge-eating syndromes and noneating-disordered overweight across adolescence. High-risk subgroups in both sexes-and their particularly unfavorable outcomes in girls-underscore the need for sex-specific early identification strategies that consider longitudinal constellations of multiple ED symptoms and weight status rather than single indicators.

目的:饮食失调(EDs)经常出现在青春期,但不同核心特征的发展轨迹仍不清楚。方法:前瞻性社区研究纳入N = 898名参与者,年龄9.5-17.5岁(47.6%女性,年龄11.8±1.4岁),每年随访2-6(3.4±1.2)年。采用基于群体的多轨迹模型(GBMTM)分别分析了女孩和男孩的暴食、克制、体重补偿行为(儿童饮食失调检查问卷)和体重指数-标准差评分(BMI-SDS)的多变量轨迹。ED和一般精神病理学用于验证和结果比较。结果:GBMTM确定了女孩ED症状和BMI-SDS的5种不同轨迹,男孩6种。低、正常和高BMI-SDS的低症状轨迹是最常见的,只表现出轻微的、短暂的ED症状。在男孩中,在不同的BMI-SDS水平下,其发展轨迹主要以稳定的ED症状为特征,而在女孩中,ED症状随着时间的推移表现出更明显的变化。在两性中,两个高危亚组反映了暴食和暴饮暴食的模式,并且随着年龄的增长,ED症状升高或增加,这在女孩中尤其与ED和一般精神病理的增加有关。讨论:GBMTM结果支持青春期暴食症/暴饮暴食综合征和非饮食失调超重的发育特异性。两种性别的高危亚群——尤其是女孩的不利结果——强调了针对性别的早期识别策略的必要性,即考虑多种ED症状和体重状况的纵向排列,而不是单一指标。
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引用次数: 0
Resilience and Disordered Eating Among Japanese Adolescents: A Population-Based Cohort Study. 日本青少年的适应力和饮食失调:一项基于人群的队列研究。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-02-01 DOI: 10.1002/eat.70041
Nihaal Rahman, Kazue Ishitsuka, Aurélie Piedvache, Makiko Sampei, Naho Morisaki

Objective: The relationship between resilience and eating disorder psychopathology among adolescents has been understudied. This study assessed prospective associations between baseline resilience and subsequent eating disorder psychopathology in a nationally representative longitudinal cohort of Japanese adolescents.

Method: We conducted a prospective cohort study with participants in grades 5-9 (10-15 years; n = 987) drawn from the Japan Adolescent and Youth longitudinal study. In 2021, resilience was measured using the Rasch-validated version of the Child and Youth Resilience Measure, while eating disorder psychopathology was assessed at the 2022 follow-up using the Eating Disorder Examination-Questionnaire adapted for children. Both instruments were child-reported. Linear regression examined relationships between resilience scores and eating disorder psychopathology, adjusting for grade and maternal education.

Results: Higher overall resilience (β = -0.116; 95% confidence interval [CI]: -0.198, -0.034), personal resilience (-0.113; 95% CI: -0.196, -0.031), and caregiver resilience (-0.109; 95% CI: -0.192, -0.026) were each significantly associated with lower eating disorder psychopathology scores. Higher caregiver resilience was significantly associated with lower levels of restraint over eating (-0.093; 95% CI: -0.179, -0.006), while higher personal resilience was significantly associated with lower levels of guilt about eating (-0.103; 95% CI: -0.200, -0.005).

Discussion: Higher resilience was associated with fewer eating disorder symptoms among adolescents. Personal resilience was observed to be more salient for some symptoms, while caregiver resilience was more salient for others. These findings highlight the multifaceted role of resilience and suggest that interventions may benefit from strengthening both adolescents' individual coping resources and the supportive capacities of caregivers.

目的:探讨青少年心理弹性与进食障碍心理病理的关系。本研究在一项具有全国代表性的日本青少年纵向队列中评估了基线弹性与随后的饮食失调精神病理之间的前瞻性关联。方法:我们对来自日本青少年纵向研究的5-9年级(10-15岁;n = 987)的参与者进行了一项前瞻性队列研究。2021年,使用rasch验证版的儿童和青年弹性测量来测量弹性,而在2022年的随访中,使用适用于儿童的饮食失调检查问卷来评估饮食失调精神病理学。两种仪器都是儿童报告的。线性回归检验了弹性得分与饮食失调精神病理之间的关系,调整了年级和母亲教育程度。结果:较高的整体心理弹性(β = -0.116; 95%可信区间[CI]: -0.198, -0.034)、个人心理弹性(-0.113;95% CI: -0.196, -0.031)和照顾者心理弹性(-0.109;95% CI: -0.192, -0.026)均与较低的饮食失调精神病理学评分显著相关。较高的照顾者弹性与较低的饮食克制水平显著相关(-0.093;95% CI: -0.179, -0.006),而较高的个人弹性与较低的饮食内疚水平显著相关(-0.103;95% CI: -0.200, -0.005)。讨论:在青少年中,较高的适应力与较少的饮食失调症状相关。观察到个人弹性对某些症状更为突出,而照顾者弹性对其他症状更为突出。这些发现强调了弹性的多方面作用,并表明干预措施可能受益于加强青少年的个人应对资源和照顾者的支持能力。
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引用次数: 0
Serum Leptin in Youth and Young Adults With Avoidant/Restrictive Food Intake Disorder Across the Weight Spectrum. 在体重谱上有回避/限制性食物摄入障碍的青年和青壮年血清瘦素。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-02-01 DOI: 10.1002/eat.70043
Taylor L Rezeppa, Vittoria Trolio, Lilian P Palmer, Stefania Yee, Lauren Breithaupt, Megan Kuhnle, Julia Gydus, Kristine Hauser, Franziska Plessow, Kamryn T Eddy, Madhusmita Misra, Nadia Micali, Jennifer J Thomas, Elizabeth A Lawson, Helen Burton-Murray, Kendra R Becker

Objective: Avoidant/restrictive food intake disorder (ARFID) involves restrictive eating driven by sensory sensitivity, low interest in food, or fear of negative consequences of eating. ARFID affects males and females equally and presents across the weight spectrum. Leptin, an anorexigenic hormone linked to adiposity, may contribute to low hunger and early satiety in ARFID. Prior findings indicate low leptin levels in low-weight females with ARFID; however, the role of leptin in ARFID across weight status and sex remains unknown. We hypothesized that youth with full/subthreshold ARFID, including a subgroup of low-weight males, would exhibit lower fasting leptin levels than healthy controls (HCs). We explored cross-sectional and longitudinal associations between leptin and clinical characteristics.

Method: Participants were youth aged 10-23 years (BMI percentile M [SD] = 41.4 (33.6)) with full/subthreshold ARFID (n = 95; 49.5% female) and HCs (n = 28; 50.0% female). At baseline, participants completed questionnaires, a fasted blood draw, and a diagnostic interview for ARFID, readministered at 1- and 2year follow-ups.

Results: Leptin levels did not differ between ARFID and HC groups. Low-weight ARFID males had significantly lower leptin than HC males (η2 = 0.258); however, this difference was nonsignificant after adjusting for BMI percentile. Leptin showed medium-to-large positive associations with age, BMI, and anxiety but not appetite or ARFID severity. Baseline leptin did not predict symptom or weight changes longitudinally.

Discussion: Hypoleptinemia was only evident in low-weight ARIFD and strongly correlated with BMI percentile. However, relationships with anxiety may suggest additional roles of leptin in underlying ARFID psychopathology. Findings should be replicated in larger, more representative samples.

目的:回避/限制性食物摄入障碍(ARFID)包括由感觉敏感、对食物不感兴趣或对饮食负面后果的恐惧驱动的限制性饮食。ARFID对男性和女性的影响是平等的,并且表现在整个体重谱上。瘦素是一种与肥胖相关的无氧激素,可能有助于ARFID患者的低饥饿感和早饱腹感。先前的研究结果表明,低体重ARFID女性瘦素水平低;然而,瘦素在ARFID中跨体重和性别的作用仍然未知。我们假设患有完全/阈下ARFID的青年,包括低体重男性亚组,其空腹瘦素水平低于健康对照(hc)。我们探讨了瘦素与临床特征之间的横断面和纵向关联。方法:参与者为10-23岁的青年(BMI百分位数M [SD] = 41.4(33.6)),伴有完全/阈下ARFID (n = 95;女性49.5%)和hc (n = 28;女性50.0%)。在基线时,参与者完成问卷调查、空腹抽血和ARFID诊断性访谈,并在1年和2年的随访中重新服用。结果:瘦素水平在ARFID组和HC组之间没有差异。低体重ARFID男性瘦素显著低于HC男性(η2 = 0.258);然而,在调整BMI百分位数后,这种差异不显著。瘦素与年龄、BMI和焦虑呈正相关,但与食欲或ARFID严重程度无关。基线瘦素不能预测症状或体重的纵向变化。讨论:低肽血症仅在低体重ARIFD中明显,且与BMI百分位数密切相关。然而,与焦虑的关系可能提示瘦素在潜在ARFID精神病理中的其他作用。研究结果应该在更大、更有代表性的样本中得到重复。
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引用次数: 0
The Effectiveness of Psychological Treatment for Anorexia Nervosa in Adolescents: A Critical Review of Randomized Controlled Trials. 青少年神经性厌食症心理治疗的有效性:随机对照试验综述。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-01-30 DOI: 10.1002/eat.70031
Renée A Broersma, Moniek A J Zeegers, Jesse Roest, Ramon J L Lindauer, Fabienne Harteveld, Peer van der Helm, James Lock, Mark Assink

Objective: Although international treatment guidelines for eating disorders recommend varying psychological approaches for adolescents with anorexia nervosa (AN), most existing reviews have combined adolescent and adult samples, leaving the overall evidence base for this population poorly defined. This systematic review is the first to synthesize randomized controlled trials (RCTs) of psychological treatments for adolescents with AN across outpatient, inpatient, and day-patient settings.

Method: A systematic search of databases (e.g., PubMed, APA PsycINFO) identified 22 relevant studies through June 2025. Eligible studies focused on adolescents (ages 8-18 years) with AN undergoing psychological treatment.

Results: Evidence from the nine RCTs consistently indicates that family therapy produces significant positive effects on somatic parameters (e.g., weight) and short-term eating-disorder symptoms. In four, mostly underpowered comparative RCTs, outpatient family therapy showed small-to-moderate effect sizes over individual therapy, though these were restricted to outcomes related to medical recovery. For inpatient care, a limited evidence base suggests that shorter inpatient treatment followed by outpatient care may achieve outcomes comparable to extended hospitalization. Psychological modules delivered during inpatient treatment (e.g., Cognitive Remediation Therapy, CBT-Insomnia) showed some improvements confined to narrow symptom domains but did not translate into broader recovery.

Conclusion: The evidence base remains limited, with few RCTs in adolescents with AN and a geographically narrow, demographically homogeneous sample, predominantly girls from Western settings. Family therapy is supported as the first-line treatment, yet substantial uncertainties persist. Larger and more inclusive RCTs are needed to clarify mechanisms of change, long-term outcomes, and the effectiveness of individual-focused approaches.

目的:尽管国际饮食失调治疗指南推荐对患有神经性厌食症(AN)的青少年采用不同的心理治疗方法,但大多数现有综述将青少年和成人样本结合起来,使得这一人群的总体证据基础定义不清。本系统综述首次综合了门诊、住院和日间青少年AN心理治疗的随机对照试验(rct)。方法:系统检索数据库(例如PubMed, APA PsycINFO),确定了截至2025年6月的22项相关研究。符合条件的研究集中在接受心理治疗的AN青少年(8-18岁)。结果:9项随机对照试验的证据一致表明,家庭治疗对躯体参数(如体重)和短期饮食失调症状有显著的积极影响。在四项大多效力不足的对照随机对照试验中,门诊家庭治疗比个体治疗显示出小到中等的效果,尽管这些结果仅限于与医疗康复相关的结果。对于住院治疗,有限的证据基础表明,较短的住院治疗后再进行门诊治疗可能达到与延长住院治疗相当的结果。在住院治疗期间提供的心理模块(例如,认知补救疗法,cbt -失眠)在狭窄的症状领域显示出一些改善,但没有转化为更广泛的恢复。结论:证据基础仍然有限,针对AN青少年的随机对照试验很少,而且样本地域狭窄,人口统计学上同质,主要是来自西方国家的女孩。家庭治疗作为一线治疗得到支持,但仍存在很大的不确定性。需要更大规模、更具包容性的随机对照试验来阐明变化机制、长期结果和以个体为重点的方法的有效性。
{"title":"The Effectiveness of Psychological Treatment for Anorexia Nervosa in Adolescents: A Critical Review of Randomized Controlled Trials.","authors":"Renée A Broersma, Moniek A J Zeegers, Jesse Roest, Ramon J L Lindauer, Fabienne Harteveld, Peer van der Helm, James Lock, Mark Assink","doi":"10.1002/eat.70031","DOIUrl":"https://doi.org/10.1002/eat.70031","url":null,"abstract":"<p><strong>Objective: </strong>Although international treatment guidelines for eating disorders recommend varying psychological approaches for adolescents with anorexia nervosa (AN), most existing reviews have combined adolescent and adult samples, leaving the overall evidence base for this population poorly defined. This systematic review is the first to synthesize randomized controlled trials (RCTs) of psychological treatments for adolescents with AN across outpatient, inpatient, and day-patient settings.</p><p><strong>Method: </strong>A systematic search of databases (e.g., PubMed, APA PsycINFO) identified 22 relevant studies through June 2025. Eligible studies focused on adolescents (ages 8-18 years) with AN undergoing psychological treatment.</p><p><strong>Results: </strong>Evidence from the nine RCTs consistently indicates that family therapy produces significant positive effects on somatic parameters (e.g., weight) and short-term eating-disorder symptoms. In four, mostly underpowered comparative RCTs, outpatient family therapy showed small-to-moderate effect sizes over individual therapy, though these were restricted to outcomes related to medical recovery. For inpatient care, a limited evidence base suggests that shorter inpatient treatment followed by outpatient care may achieve outcomes comparable to extended hospitalization. Psychological modules delivered during inpatient treatment (e.g., Cognitive Remediation Therapy, CBT-Insomnia) showed some improvements confined to narrow symptom domains but did not translate into broader recovery.</p><p><strong>Conclusion: </strong>The evidence base remains limited, with few RCTs in adolescents with AN and a geographically narrow, demographically homogeneous sample, predominantly girls from Western settings. Family therapy is supported as the first-line treatment, yet substantial uncertainties persist. Larger and more inclusive RCTs are needed to clarify mechanisms of change, long-term outcomes, and the effectiveness of individual-focused approaches.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Prevention of Eating Disorders in Australian Adolescents: A Modeled Cost-Effectiveness Study. 澳大利亚青少年饮食失调的预防:一项模拟成本效益研究。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-01-30 DOI: 10.1002/eat.70048
Long Khanh-Dao Le, Eng Joo Tan, Phillipa Hay, Jaithri Ananthapavan, Yong Yi Lee, Cathrine Mihalopoulos

Objective: Prevention programs for eating disorders (EDs) have the potential to reduce the onset of these diseases and improve the mental health and well-being of the general population. However, there is mixed evidence on whether routine implementation of such programs at the population level is cost-effective. This study intends to investigate the cost-effectiveness of an evidence-based preventive intervention for EDs, the Body Project, at the population level.

Method: The Body Project is a targeted school-based intervention that aims to prevent EDs among adolescents. A Markov model was developed to evaluate the incremental cost-effectiveness of the hypothetical implementation of the Body Project among female-identifying secondary students in Australia versus a 'no intervention' comparator. A cost-utility analysis was conducted from a "healthcare and limited education" sector perspective with costs and health impacts modeled over the lifetime of the target population. An incremental cost-effectiveness ratio (ICER), expressed as cost per health-adjusted life year (HALY) gained, was calculated. Sensitivity analyses were done to test model assumptions.

Results: If implemented across 1416 Australian secondary schools, the modeled Body Project consisting of four group sessions for eligible girls aged 15-18 years with high body image concerns was estimated to yield about 92 HALYs (95% CI: 58-131) and save $2.56 million in future healthcare costs at an implementation cost of $1.88 million (95% CI: $1.62-$2.15 million).

Discussion: The Body Project intervention is likely to represent good value for money. Successful implementation of this program will require further research into its feasibility and acceptability among schools and the wider community.

目的:饮食失调(EDs)的预防项目有可能减少这些疾病的发病,改善一般人群的心理健康和福祉。然而,关于在人口水平上例行实施这类计划是否具有成本效益,证据不一。本研究旨在调查以证据为基础的ed预防干预的成本效益,即Body项目,在人口水平上。方法:身体项目是一项以学校为基础的针对性干预,旨在预防青少年中的ed。开发了一个马尔可夫模型来评估在澳大利亚女性识别中学生中假设实施身体项目与“无干预”比较的增量成本效益。从“保健和有限教育”部门的角度进行了成本效用分析,在目标人口的整个生命周期内对成本和健康影响进行了建模。计算增量成本-效果比(ICER),表示为获得的每个健康调整生命年的成本(HALY)。进行敏感性分析以检验模型假设。结果:如果在1416所澳大利亚中学实施,模型身体项目由四组会议组成,针对符合条件的15-18岁高度关注身体形象的女孩,估计产生约92个HALYs (95% CI: 58-131),并节省256万美元的未来医疗保健费用,实施成本为188万美元(95% CI: 162 - 215万美元)。讨论:身体项目干预可能代表物有所值。这一计划的成功实施需要进一步研究其可行性以及学校和更广泛社区的可接受性。
{"title":"The Prevention of Eating Disorders in Australian Adolescents: A Modeled Cost-Effectiveness Study.","authors":"Long Khanh-Dao Le, Eng Joo Tan, Phillipa Hay, Jaithri Ananthapavan, Yong Yi Lee, Cathrine Mihalopoulos","doi":"10.1002/eat.70048","DOIUrl":"https://doi.org/10.1002/eat.70048","url":null,"abstract":"<p><strong>Objective: </strong>Prevention programs for eating disorders (EDs) have the potential to reduce the onset of these diseases and improve the mental health and well-being of the general population. However, there is mixed evidence on whether routine implementation of such programs at the population level is cost-effective. This study intends to investigate the cost-effectiveness of an evidence-based preventive intervention for EDs, the Body Project, at the population level.</p><p><strong>Method: </strong>The Body Project is a targeted school-based intervention that aims to prevent EDs among adolescents. A Markov model was developed to evaluate the incremental cost-effectiveness of the hypothetical implementation of the Body Project among female-identifying secondary students in Australia versus a 'no intervention' comparator. A cost-utility analysis was conducted from a \"healthcare and limited education\" sector perspective with costs and health impacts modeled over the lifetime of the target population. An incremental cost-effectiveness ratio (ICER), expressed as cost per health-adjusted life year (HALY) gained, was calculated. Sensitivity analyses were done to test model assumptions.</p><p><strong>Results: </strong>If implemented across 1416 Australian secondary schools, the modeled Body Project consisting of four group sessions for eligible girls aged 15-18 years with high body image concerns was estimated to yield about 92 HALYs (95% CI: 58-131) and save $2.56 million in future healthcare costs at an implementation cost of $1.88 million (95% CI: $1.62-$2.15 million).</p><p><strong>Discussion: </strong>The Body Project intervention is likely to represent good value for money. Successful implementation of this program will require further research into its feasibility and acceptability among schools and the wider community.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceived Coach and Teammate Weight/Shape-Related Beliefs and Disordered Eating in NCAA Swimmers. 感知教练和队友的体重/体型相关信念和饮食失调在NCAA游泳运动员。
IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2026-01-28 DOI: 10.1002/eat.70040
Claire K Pinson, Kathryn R Fox, Guido K W Frank, Jill M Hooley, Kristin N Javaras

Objective: The distinct associations of coaches' and teammates' beliefs about ideal body weight/shape with athletes' disordered eating remain unclear. This study examined how athletes' perceptions of their coaches' and teammates' weight- and shape-related beliefs were associated with eating disorder symptoms and body dissatisfaction among National Collegiate Athletic Association (NCAA) swimmers. We hypothesized that both perceived coaches' and teammates' beliefs would be significantly associated with eating disorder symptoms and body dissatisfaction.

Method: Participants were 190 in-season NCAA swimmers (81% female) who completed a newly developed brief questionnaire designed to assess perceived coach and teammate weight/shape-related beliefs (Coach and Teammate Weight/Shape Beliefs Questionnaire; CTWSBQ), as well as scales assessing eating disorder symptoms (Eating Disorder Examination-Questionnaire, EDE-Q) and thinness- and muscularity-related body dissatisfaction (ATHLETE Questionnaire Your Body and Sports subscale and Drive for Muscularity Scale, respectively). Multiple linear regression was used to model disordered eating as a function of CTWSBQ Teammate and Coach scores and covariates.

Results: Only the CTWSBQ Teammate score was significantly associated with EDE-Q Global (ΔR2 = 0.04) and ATHLETE (ΔR2 = 0.04) scores after adjustment for both demographic and psychological covariates. CTWSBQ Coach, but not Teammate, scores were significantly associated with Drive for Muscularity scores (ΔR2 = 0.02) after adjustment for covariates.

Discussion: Findings from this cross-sectional study suggest distinct patterns of association for perceived teammate versus coach weight/shape-related beliefs across eating disorder symptoms, thinness-related concerns, and muscularity-related concerns in NCAA swimmers. Future work should test these patterns prospectively and determine whether they can inform prevention and education content for athletes and coaches.

目的:教练员和队友的理想体重/体型信念与运动员饮食失调之间的显著相关性尚不清楚。这项研究调查了运动员对教练和队友的体重和体型的看法是如何与全国大学体育协会(NCAA)游泳运动员的饮食失调症状和身体不满联系在一起的。我们假设教练和队友的信念都与饮食失调症状和身体不满显著相关。方法:参与者为190名NCAA赛季游泳运动员(81%为女性),他们完成了一份新开发的简短问卷,旨在评估教练和队友的体重/体型相关信念(教练和队友体重/体型信念问卷;CTWSBQ),以及评估饮食失调症状的量表(饮食失调检查问卷,ed - q)和与瘦和肌肉相关的身体不满(运动员问卷你的身体和运动亚量表和肌肉化驱动量表)。采用多元线性回归对饮食失调进行建模,并将其作为CTWSBQ队友和教练得分和协变量的函数。结果:调整人口统计学和心理协变量后,只有CTWSBQ队友得分与EDE-Q Global (ΔR2 = 0.04)和ATHLETE (ΔR2 = 0.04)得分显著相关。调整协变量后,CTWSBQ Coach得分与Drive for muscular得分显著相关(ΔR2 = 0.02),而队友得分则不显著。讨论:这项横断面研究的结果表明,在NCAA游泳运动员中,与饮食失调症状、与瘦相关的担忧和与肌肉相关的担忧中,感知队友与教练体重/形状相关的信念存在明显的关联模式。未来的工作应该对这些模式进行前瞻性的测试,并确定它们是否可以为运动员和教练提供预防和教育内容。
{"title":"Perceived Coach and Teammate Weight/Shape-Related Beliefs and Disordered Eating in NCAA Swimmers.","authors":"Claire K Pinson, Kathryn R Fox, Guido K W Frank, Jill M Hooley, Kristin N Javaras","doi":"10.1002/eat.70040","DOIUrl":"https://doi.org/10.1002/eat.70040","url":null,"abstract":"<p><strong>Objective: </strong>The distinct associations of coaches' and teammates' beliefs about ideal body weight/shape with athletes' disordered eating remain unclear. This study examined how athletes' perceptions of their coaches' and teammates' weight- and shape-related beliefs were associated with eating disorder symptoms and body dissatisfaction among National Collegiate Athletic Association (NCAA) swimmers. We hypothesized that both perceived coaches' and teammates' beliefs would be significantly associated with eating disorder symptoms and body dissatisfaction.</p><p><strong>Method: </strong>Participants were 190 in-season NCAA swimmers (81% female) who completed a newly developed brief questionnaire designed to assess perceived coach and teammate weight/shape-related beliefs (Coach and Teammate Weight/Shape Beliefs Questionnaire; CTWSBQ), as well as scales assessing eating disorder symptoms (Eating Disorder Examination-Questionnaire, EDE-Q) and thinness- and muscularity-related body dissatisfaction (ATHLETE Questionnaire Your Body and Sports subscale and Drive for Muscularity Scale, respectively). Multiple linear regression was used to model disordered eating as a function of CTWSBQ Teammate and Coach scores and covariates.</p><p><strong>Results: </strong>Only the CTWSBQ Teammate score was significantly associated with EDE-Q Global (ΔR<sup>2</sup> = 0.04) and ATHLETE (ΔR<sup>2</sup> = 0.04) scores after adjustment for both demographic and psychological covariates. CTWSBQ Coach, but not Teammate, scores were significantly associated with Drive for Muscularity scores (ΔR<sup>2</sup> = 0.02) after adjustment for covariates.</p><p><strong>Discussion: </strong>Findings from this cross-sectional study suggest distinct patterns of association for perceived teammate versus coach weight/shape-related beliefs across eating disorder symptoms, thinness-related concerns, and muscularity-related concerns in NCAA swimmers. Future work should test these patterns prospectively and determine whether they can inform prevention and education content for athletes and coaches.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146068513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Journal of Eating Disorders
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