Journal of Pain最新文献

{"title":"Re: Letter to the Editor Re: Effects of centrally acting analgesics on resting-state electroencephalography biomarker candidates of chronic pain.","authors":"Paul Theo Zebhauser, Markus Ploner","doi":"10.1016/j.jpain.2026.106183","DOIUrl":"10.1016/j.jpain.2026.106183","url":null,"abstract":"","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":" ","pages":"106183"},"PeriodicalIF":4.0,"publicationDate":"2026-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of positive, neutral, and negative expectations about spinal manipulative therapy on pain intensity in chronic low back pain: A randomized controlled trial","authors":"Bianca Emanuelli Saes Campanha ,&nbsp;Thamiris Costa de Lima ,&nbsp;Helen Cristina Nogueira Carrer ,&nbsp;Steven Z. George ,&nbsp;Felipe J.J. Reis ,&nbsp;Thaís Cristina Chaves","doi":"10.1016/j.jpain.2025.106177","DOIUrl":"10.1016/j.jpain.2025.106177","url":null,"abstract":"<div><div>Spinal manipulative therapy (SMT) has favorable, but small effects on pain intensity to treat chronic low back pain (CLBP). However, there is the potential for these effects to be enhanced by manipulating treatment expectations. Our objective was to investigate the effect of verbally delivered treatment expectations in association with SMT on pain intensity for individuals with CLBP. Our sample consisted of sixty participants who were randomly allocated to three groups in which verbally delivered expectations (positive [PEG], neutral [NEUG], and negative [NEG]) were administered by video before one session of SMT. Pain intensity (primary outcome), global perceived effect (GPE) of improvement, disability, participants’ expectations, and empathy as secondary outcomes were assessed immediately post-treatment and pain intensity, GPE, and disability at the 3-month follow-up. Participants were interviewed about their perceptions regarding the videos. Pain intensity significantly decreased in the PEG and NEUG immediately after the SMT session (mean difference=MD), PEG - MD=-1.9 [95% CI −3.4 - −0.3] and NEUG - MD=-1.6 [95% CI −3.2 - −0.05], both when compared to the NEG. However, these findings weren’t maintained at the 3-month follow-up. No significant changes in GPE and disability were observed between groups. Our findings suggest that positive and neutral verbally delivered treatment expectations resulted in short-term SMT hypoalgesia compared to negative expectations; however, these effects did not persist at 3-month follow-up. Such results suggest that both positive and neutral SMT-related expectations should be adopted when communicating the expected treatment effects to patients.</div></div><div><h3>Clinical trials registration number</h3><div>NCT05996991, protocol registration: August 2023, study start date 1st October, 2023</div></div><div><h3>Perspective</h3><div>Our findings showed that using positive or neutral verbally delivered expectations has the potential to enhance short-term hypoalgesia associated with SMT in CLBP.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"40 ","pages":"Article 106177"},"PeriodicalIF":4.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality matters: Interpreting amputation outcomes in CRPS - Authors reply.","authors":"Yannick L Gilanyi, Michael C Ferraro, Andreas Goebel, Neil E O'Connell, Matthew D Jones, Saurab Sharma, Debbie Bean, Sylvia M Gustin, James H McAuley","doi":"10.1016/j.jpain.2025.106178","DOIUrl":"10.1016/j.jpain.2025.106178","url":null,"abstract":"","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":" ","pages":"106178"},"PeriodicalIF":4.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy and safety of repetitive transcranial magnetic stimulation for comorbid chronic low back pain and insomnia: A randomized, double-blind, sham-controlled pilot trial","authors":"Jeremy R. Chang ,&nbsp;Eliza R. Sun ,&nbsp;Minxia Jin ,&nbsp;Leo GH Lin ,&nbsp;Shirley X. Li ,&nbsp;Jannet LC Lee ,&nbsp;Frank F. Huang ,&nbsp;Rachel LC Kwan ,&nbsp;Daniel KY Zheng ,&nbsp;Dino Samartzis ,&nbsp;Siu-Ngor Fu ,&nbsp;Arnold YL Wong","doi":"10.1016/j.jpain.2025.106180","DOIUrl":"10.1016/j.jpain.2025.106180","url":null,"abstract":"<div><div>Repetitive transcranial magnetic stimulation (rTMS) has shown efficacy in treating chronic pain or insomnia independently. Given the high prevalence of insomnia in individuals with chronic low back pain (CLBP), this pilot randomized controlled trial assessed the feasibility, acceptability, and preliminary efficacy of rTMS targeting either the left primary motor cortex (M1) or right dorsolateral prefrontal cortex (DLPFC) in individuals with comorbid CLBP and insomnia. Thirty-six participants were randomized to receive sham-rTMS, active M1-rTMS (10 Hz, 1500 pulses), or active DLPFC-rTMS (1 Hz, 1500 pulses) over 10 sessions for two weeks (five sessions per week), with a one-month follow-up. Primary outcomes were feasibility and acceptability. Secondary outcomes included pain intensity, insomnia severity, disability, psychological measures, subjective and objective sleep parameters, pain threshold, temporal summation of pain, and conditioned pain modulation. rTMS was highly feasible and acceptable, as evidenced by excellent session attendance and no participant attrition. No serious adverse events were reported. Both active M1- and DLPFC-rTMS significantly reduced pain intensity and enhanced the descending pain inhibitory pathways compared with sham stimulation. Importantly, DLPFC-rTMS was superior to sham in reducing insomnia severity, objective wake after sleep onset, and temporal summation of pain. These findings suggest that rTMS is a feasible, well-tolerated, and promising intervention for individuals with comorbid CLBP and insomnia. While both stimulation protocols yielded analgesic benefits, DLPFC-rTMS may confer additional advantages for addressing sleep disturbance. Further full-scale randomized clinical trials are warranted to validate these preliminary findings and optimize rTMS protocols for this complex clinical population.</div></div><div><h3>Perspective</h3><div>rTMS was feasible for comorbid chronic low back pain and insomnia, with DLPFC stimulation yielding superior effects on sleep disturbance and pain processing. Further large-scale RCTs using neuroimaging are warranted to validate and expand upon these preliminary results and elucidate the neurophysiological basis of treatment efficacy.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"40 ","pages":"Article 106180"},"PeriodicalIF":4.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How do people with fibromyalgia interpret ambiguous cues in empathy-related healthcare scenarios?","authors":"Maria Planes Alias ,&nbsp;David J Moore ,&nbsp;Nicholas Fallon ,&nbsp;Katie Herron ,&nbsp;Charlotte Krahé","doi":"10.1016/j.jpain.2025.106181","DOIUrl":"10.1016/j.jpain.2025.106181","url":null,"abstract":"<div><div>Empathic communication is essential for high-quality healthcare, yet patients must often interpret subtle and ambiguous interpersonal cues during healthcare encounters. In such contexts, prior experiences and cognitive-affective processes may shape interpretations in biased ways. In Fibromyalgia Syndrome (FMS), a frequently stigmatised and ‘invisible’ condition, such biases may influence how patients perceive unclear messages from healthcare professionals. While interpretation bias for pain-related information has been explored, bias in interpreting social-emotional information has not. This study investigated interpretations of ambiguous social-emotional cues from healthcare professionals in individuals with FMS (<em>n</em> = 65), compared with those with other chronic pain conditions (<em>n</em> = 51) and pain-free controls (<em>n</em> = 77). Participants completed a novel scenario-based task assessing the perceived likelihood of positive, neutral, and negative interpretations of ambiguous clinical situations. Validated self-report measures of psychological distress and perceived clinical empathy were also administered. Results showed that individuals with FMS were significantly more likely to endorse negative interpretations and less likely to endorse positive ones relative to both comparison groups, even after controlling for depression, anxiety, and stress. The FMS group also reported greater psychological distress and lower perceived empathy. Moreover, negative interpretation bias was associated with greater distress and lower perceived clinical empathy, while positive bias showed the opposite pattern. These findings suggest that individuals with FMS interpret ambiguous healthcare communication through a distinct cognitive-affective lens. This highlights that patient–provider interactions are not experienced uniformly across chronic pain populations, and that interpretative biases should be considered to improve healthcare communication.</div></div><div><h3>Perspective</h3><div>We explored how individuals with fibromyalgia (compared to other chronic pain and pain-free groups) interpret empathy-related ambiguous cues from healthcare professionals. Controlling for psychological distress, the fibromyalgia group showed a stronger negative interpretation bias than both comparison groups. Understanding these socio-cognitive patterns may help improve communication and empathy in fibromyalgia care.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"40 ","pages":"Article 106181"},"PeriodicalIF":4.0,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain and functional disability in older adults with cardiovascular disease: A cross-national comparison of India, China, and Mexico","authors":"Hongtao Cheng ,&nbsp;Huijun Wu ,&nbsp;Lu Shao,&nbsp;Jie Jiang,&nbsp;Tingting Xie,&nbsp;June Zhang","doi":"10.1016/j.jpain.2025.106182","DOIUrl":"10.1016/j.jpain.2025.106182","url":null,"abstract":"<div><div>Pain is highly prevalent among older adults with cardiovascular disease (CVD) and may compromise functional independence. However, the nature of this relationship in different cultural and healthcare contexts is not well understood. We examined the association between pain and functional limitations among adults aged 60 years and older with self-reported cardiovascular disease (CVD) using nationally representative data from the Longitudinal Aging Study in India (LASI, n = 11,247), the China Health and Retirement Longitudinal Study (CHARLS, n = 3733) and the Mexican Health and Aging Study (MHAS, n = 5108). Pain was assessed through self-report, and functional status was evaluated across activities of daily living (ADL), instrumental activities of daily living (IADL), and mobility. Cross-sectional associations were estimated using multivariable logistic regression, and longitudinal analyses examined the effect of baseline pain on incident disability at 3-year follow-up in the Chinese and Mexican cohorts. Pain was reported by 43.7%, 36.2%, and 43.6% of participants in India, China, and Mexico, respectively. After adjustment for covariates, pain was significantly associated with ADL disability in all three countries (India OR=1.86, China OR=2.22, Mexico OR=2.32), with similar associations observed for IADL and mobility limitations. Strong dose–response relationships were identified between pain frequency or severity and functional limitations. Longitudinal analyses further showed that baseline pain predicted new-onset ADL and IADL disability at follow-up. These findings demonstrate that pain is consistently associated with functional decline among older adults with CVD, underscoring the importance of pain assessment and management in geriatric cardiovascular care globally.</div></div><div><h3>Perspective</h3><div>This study reveals consistent cross-national associations between pain and functional disability among older adults with cardiovascular disease. Pain independently predicts future functional decline, underscoring its value as a clinical marker for early intervention and as a modifiable target in integrated cardiovascular and geriatric care programs.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"40 ","pages":"Article 106182"},"PeriodicalIF":4.0,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are gray matter changes following pain reprocessing therapy associated with clinical improvement? A voxel-based morphometry mediation analysis","authors":"Carlos Murillo ,&nbsp;Tor D. Wager ,&nbsp;Yoni K. Ashar","doi":"10.1016/j.jpain.2025.105644","DOIUrl":"10.1016/j.jpain.2025.105644","url":null,"abstract":"<div><div>Chronic back pain (CBP) has been associated with reorganization of gray matter (GM), and treatment may reverse these GM adaptations. Prior trials testing treatment effects on GM did not included a randomized control group, found no treatment vs. control differences, or did not attempt to link treatment-induced GM changes to improvements in clinical outcomes. We addressed this gap by performing a voxel-based morphometry mediation analysis testing for effects of a psychological treatment (pain reprocessing therapy, PRT, n=44) vs. two randomized control groups (treatment as usual, n=47, and open-label placebo, n=44) on GM, and testing whether treatment-specific GM changes were associated with reductions in disability (ODI) and pain intensity (BPI). Relative to both control groups, PRT increased GM in the anterior cingulate and orbitofrontal cortex. These treatment-induced GM increases, however, did not mediate PRT effects on clinical outcomes. Instead, improvements in disability and pain were associated with GM increases in the lateral prefrontal cortex and GM decreases in the thalamus and amygdala. These findings indicate that PRT vs. control increases GM in key pain-modulatory regions, and, that clinical improvement is related to different prefrontal and subcortical GM changes in regions processing nociceptive input and regulating pain. The lack of mediation may indicate either that GM changes are not a treatment mechanism, or a lack of power to detect smaller effects. Future research is needed to better understand how treatments act on neurobiology to drive clinical improvement.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"40 ","pages":"Article 105644"},"PeriodicalIF":4.0,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardising socio-demographic data collection in pain research: Introducing consensus recommendations for a minimum dataset","authors":"Emma L. Karran ,&nbsp;Aidan G. Cashin ,&nbsp;Alessandro Chiarotto ,&nbsp;Saurab Sharma ,&nbsp;Trevor Barker ,&nbsp;Mark A. Boyd ,&nbsp;Lara J. Maxwell ,&nbsp;Vina Mohabir ,&nbsp;Jennifer Petkovic ,&nbsp;Peter Tugwell ,&nbsp;G. Lorimer Moseley","doi":"10.1016/j.jpain.2025.105645","DOIUrl":"10.1016/j.jpain.2025.105645","url":null,"abstract":"<div><div>The ‘ISSHOOs (Identifying Social factors that Stratify Health Opportunities and Outcomes) in pain research’ project has developed consensus-derived recommendations to address the inadequacy and inconsistency of socio-demographic data collection and reporting in human adult pain research. The recently published recommendations offer a highly useful, globally relevant and adaptable resource that operationalises the collection of a minimum dataset of important equity-relevant information. In this Commentary we provide a brief overview of the ISSHOOs project and the resulting recommendations – comprising Set A: the ‘minimum dataset’ and Set B: an extended dataset of optional (equity-relevant) items; and we draw attention to a separate ‘explanation and elaboration’ manuscript. We discuss the implications of routine adoption of the ISSHOOs recommendations, including limitations, implementation considerations, and the potential for both benefits and harms to be associated with their use. The overarching goal of the ISSHOOs Collaboration is to prompt a small but widespread shift in research practice that promotes research transparency, integrity and value and advances health equity for people with pain.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"39 ","pages":"Article 105645"},"PeriodicalIF":4.0,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Financial status and pain in the last week of life: Insights from a nationally representative mortality follow-back survey in England and Wales","authors":"Juan E. Correa-Morales ,&nbsp;Therese Johansson ,&nbsp;Thomas Curtis ,&nbsp;Fliss E.M. Murtagh ,&nbsp;Joanna M. Davies ,&nbsp;Katherine E. Sleeman","doi":"10.1016/j.jpain.2025.105642","DOIUrl":"10.1016/j.jpain.2025.105642","url":null,"abstract":"<div><div>Pain relief is a priority for patients and families living with advanced illness. There is evidence of socioeconomic inequality in palliative and end-of-life care, yet little is known about how pain might differ according to financial status. We analysed data collected in a mortality follow-back study carried out in England and Wales in 2023, to examine the association between subjective financial status and being affected by pain during the last week of life. Pain was proxy-reported by a family member using the Integrated Palliative Care Outcome Scale (IPOS). We report IPOS pain prevalence, its association with financial status, and whether this was mediated by access to care or moderated by location of care. Of 1194 decedents, 415 (37.9%) were severely or overwhelmingly affected by pain in the last week of life. Compared to decedents financially ‘living comfortably’, those ‘doing alright’ (IRR 1.20, 95%CI 1.01–1.43), and ‘just about getting by’ (IRR 1.31, 95%CI 1.04–1.65) were more affected by pain in the last week of life. Difficulty accessing care did not mediate this association. This association was moderated by location of care (<em>F</em>(14) =107.9, p &lt; 0.001) and was not seen in care homes. Sensitivity analysis suggested high potential for unmeasured confounders (E-values between 1.70–1.95 for the main exposure categories). This study demonstrates that lower financial status is associated with being more severely or overwhelmingly affected by pain in the last week of life.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"40 ","pages":"Article 105642"},"PeriodicalIF":4.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145801859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking measurement of movement-evoked pain with digital technology","authors":"Madelyn R. Frumkin ,&nbsp;Jingwen Zhang ,&nbsp;Ziqi Xu ,&nbsp;Salim Yakdan ,&nbsp;Braeden Benedict ,&nbsp;Saad Javeed ,&nbsp;Justin Zhang ,&nbsp;Kathleen Botterbush ,&nbsp;Burel R. Goodin ,&nbsp;Chenyang Lu ,&nbsp;Wilson Z. Ray ,&nbsp;Jacob K. Greenberg","doi":"10.1016/j.jpain.2025.105643","DOIUrl":"10.1016/j.jpain.2025.105643","url":null,"abstract":"<div><div>Movement-evoked pain (MEP) may be a useful metric for phenotyping musculoskeletal pain conditions. However, there is significant disagreement over operationalization, and no studies have assessed stability of MEP over time. Fitbit and Ecological Momentary Assessment (EMA) data were collected from adults with moderate-to-severe chronic pain schedule to receive lumbar/thoracolumbar fusion surgery (N=114). On average, participants provided 323 h of Fitbit data and 74 EMA surveys (84% completion rate). To mimic task-based assessment of MEP using the 6-minute walk test, EMA pain ratings completed within 3 h of walking at a speed ≥70spm for at least 6 min were extracted. Of the full sample, 91 individuals (80%) had any instances of pain ratings following 6-minute activity bouts (<em>Median</em>=6, <em>SD</em>=11). Post-activity pain scores exhibited good within-person consistency (ICC=.76). However, between-person differences in average pain accounted for &gt;70% of the variance in post-activity pain. MEP change scores defined as the difference between post-activity and pre-activity pain scores had poor reliability (ICC =.08). MEP change scores were not associated with average pain or factors related to the uncontrolled nature of digital assessment (e.g., activity amount, time from activity to pain report). However, MEP change scores tended to be lower when the preceding pain rating was elevated (β = -7.96, 95% Credible Interval: -9.28, -6.66), suggesting ceiling effects. Small effects of time of day and prior activity were also observed, which could contaminate MEP assessed in the lab or clinic. Continued development of digital methodologies for assessing MEP is recommended.</div></div><div><h3>Perspective</h3><div>Existing movement-evoked pain assessments have limitations. Post-activity pain ratings capture overall disability and day-to-day fluctuations in pain, rather than the relationship between movement and pain. Pre-to-post activity change scores had poor reliability when assessed naturalistically and over time. Digital methodologies capture movement-evoked pain continuously across time, contexts, and real-world environments.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"40 ","pages":"Article 105643"},"PeriodicalIF":4.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145806245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}