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Mobile applications for promoting and supporting breastfeeding: Systematic review and meta-analysis 促进和支持母乳喂养的移动应用程序:系统回顾与荟萃分析。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-10-11 DOI: 10.1111/mcn.13733
Monika Ziebart, Michael Kammermeier, Berthold Koletzko, Bernadeta Patro-Golab

Breastfeeding practices require improvement. We performed a systematic review of randomised controlled trials (RCTs) and analytic observational studies to assess effects of mobile applications (apps) aiming to support and promote breastfeeding targeting pregnant women, mothers of infants or their partners, on breastfeeding outcomes. We searched MEDLINE, EMBASE, Cochrane CENTRAL and Association of Computing Machinery Digital Library from 1 July 2008 to 29 November 2022, with lack of coverage of the most recent period before publication date being a limitation of this review. We performed meta-analyses of findings from RCTs on primary outcomes, namely early breastfeeding initiation, exclusive and any breastfeeding rates. Joanna Briggs Institute tools were used for risk of bias assessment. Six RCTs, one quasi-experimental and two cohort studies, mainly from high-income countries, were included. Most studies focused on maternal app usage starting from pregnancy. One study targeted fathers as app-users. Population characteristics, such as parity or delivery mode, apps scope of content and applied active components varied between studies. Main methodological limitations of studies were baseline differences between groups and lack of blinding. Compared to controls, app usage tended to increase the odds of exclusive breastfeeding. This nonsignificant effect was most pronounced at 1–1.5 months (n = 1294, odds ratio 1.45 (95% Confidence Interval, CI 0.83, 2.54), with considerable heterogeneity between studies [I2 77%]), but less so at 3 and 6 months post-partum. The odds of early breastfeeding initiation, any breastfeeding at all time points were similar among groups. However, two cohort studies reported increased odds of exclusive and/or any breastfeeding at different time points. In conclusion, evidence is insufficient to show sustained beneficial effects of breastfeeding promotion and support through mobile apps on breastfeeding rates.

母乳喂养的做法需要改进。我们对随机对照试验(RCT)和分析性观察研究进行了系统性回顾,以评估以孕妇、婴儿母亲或其伴侣为对象、旨在支持和促进母乳喂养的移动应用程序(App)对母乳喂养结果的影响。我们检索了 2008 年 7 月 1 日至 2022 年 11 月 29 日期间的 MEDLINE、EMBASE、Cochrane CENTRAL 和美国计算机协会数字图书馆,本综述的局限性在于没有涵盖发表日期之前的最近时期。我们对研究性试验的主要结果(即早期母乳喂养、纯母乳喂养率和任何母乳喂养率)进行了荟萃分析。乔安娜-布里格斯研究所(Joanna Briggs Institute)的工具用于评估偏倚风险。共纳入了六项研究性临床试验、一项准实验研究和两项队列研究,这些研究主要来自高收入国家。大多数研究侧重于母亲从怀孕开始使用应用程序的情况。一项研究将父亲作为应用程序用户。不同研究的研究对象特征各不相同,如准妈妈或分娩方式、应用程序的内容范围和应用的有效成分。研究在方法上的主要局限是组间基线差异和缺乏盲法。与对照组相比,使用应用程序往往会增加纯母乳喂养的几率。这种非显著影响在产后 1-1.5 个月时最为明显(n = 1294,几率比 1.45(95% 置信区间,CI 0.83,2.54),不同研究之间存在相当大的异质性[I2 77%]),但在产后 3 个月和 6 个月时则不那么明显。各组间早期开始母乳喂养和在所有时间点进行母乳喂养的几率相似。然而,有两项队列研究报告称,在不同的时间点,纯母乳喂养和/或任何母乳喂养的几率都有所增加。总之,目前还没有足够的证据表明,通过手机应用推广和支持母乳喂养对母乳喂养率有持续的有益影响。
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引用次数: 0
Barriers and facilitators to healthy eating during post-partum among non-Hispanic Black mothers 非西班牙裔黑人母亲产后健康饮食的障碍和促进因素。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-10-11 DOI: 10.1111/mcn.13741
Melissa C. Kay, Margaret Bentley, Heather Wasser

Maternal diet is a key predictor of child diet, yet an in-depth inquiry into the barriers and facilitators for the adoption of healthy eating behaviours during the post-partum period is lacking, specifically for non-Hispanic Black mothers. This study used qualitative research methods to investigate healthy eating practices among a sample of non-Hispanic Black mothers participating in a family-based obesity prevention intervention. In-depth interviews were conducted with 22 mothers who participated in the Mothers and Others: Family-based Obesity Prevention for Infants and Toddlers intervention trial. Interviews were audio-recorded and transcribed verbatim. A deductive and inductive process was used to develop a consensus codebook; once the data were coded, matrices were developed to explore the data and identify similarities and differences between respondents. Relevant themes were identified, and salient quotes were used to illustrate each theme. Mothers believed that time and taste were significant barriers to eating healthy. Social influence and social support had both positive and negative influences on mothers' ability to adopt healthy eating behaviours. Despite their children often being a facilitator to healthy eating, many mothers struggled with finding the time, energy and desire to focus on themselves when it came to healthy eating. Many mothers were intent on preparing healthy meals and snacks for their children but did not prepare them for themselves. Future interventions should focus on the importance of role-modelling healthy eating behaviours for their children and include behaviour change strategies that incorporate skill-building activities emphasizing time-saving methods for planning and preparing healthy meals and snacks for the whole family to eat.

母亲的饮食是预测儿童饮食的一个关键因素,但目前还缺乏对产后期间采取健康饮食行为的障碍和促进因素的深入调查,特别是对非西班牙裔黑人母亲的调查。本研究采用定性研究方法,调查了参与家庭肥胖预防干预的非西班牙裔黑人母亲的健康饮食实践。研究人员对参加 "母亲和其他人 "项目的 22 位母亲进行了深入访谈:婴幼儿家庭式肥胖预防干预试验的 22 位母亲进行了深入访谈。对访谈进行了录音和逐字记录。我们采用了演绎和归纳的方法来编制一致同意的编码手册;对数据进行编码后,我们编制了矩阵来探索数据并确定受访者之间的异同。确定了相关的主题,并用突出的引文来说明每个主题。母亲们认为,时间和口味是饮食健康的主要障碍。社会影响和社会支持对母亲采取健康饮食行为的能力既有积极影响,也有消极影响。尽管孩子往往是健康饮食的促进因素,但在健康饮食问题上,许多母亲都很难找到时间、精力和愿望来关注自己。许多母亲一心想为孩子准备健康的正餐和零食,却没有为自己准备。未来的干预措施应侧重于为孩子树立健康饮食行为榜样的重要性,并纳入行为改变策略,其中包括技能培养活动,强调为全家人计划和准备健康正餐和零食的省时方法。
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引用次数: 0
The impact of web-based education provided to parents on the nutritional risk of preschoolers: A quasi-experimental study 向家长提供网络教育对学龄前儿童营养风险的影响:准实验研究。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-10-10 DOI: 10.1111/mcn.13735
Merve Azak, Duygu Gözen

The purpose of this study was to evaluate the effectiveness of web-based nutrition education for parents of preschool children in reducing nutritional risk. The study was conducted in a one-group pretest–posttest quasi-experimental design. Parents of 3–5-year-old children from 11 preschools in Istanbul participated. They underwent a web-based nutrition education program. The NutriSTEP assessment tool was used to evaluate the nutritional risk score as a pretest assessment, followed by the training program. Posttests were conducted at 1- and 3-month intervals. Before the intervention, 55.8% of the children exhibited high nutritional risk. After the intervention, this percentage decreased significantly at the 1-month and 3-month follow-ups, with 94.2% and 93.6% of the children classified as low risk, respectively. The analysis also revealed significant associations between children's eating behaviours and factors such as maternal education, family income and family structure. As a result, web-based nutrition education was effective in reducing nutritional risk among preschool children. The findings underscore the importance of using technology for nutrition interventions, especially in diverse populations. The training program's simple, short and understandable video increased participants' interest in the training and encouraged regular follow-up.

本研究旨在评估针对学龄前儿童家长的网络营养教育在降低营养风险方面的效果。研究采用了一组前测-后测的准实验设计。来自伊斯坦布尔 11 所幼儿园的 3-5 岁儿童的家长参加了研究。他们接受了基于网络的营养教育计划。NutriSTEP 评估工具用于评估营养风险分数,作为前测评估,然后再进行培训计划。每隔 1 个月和 3 个月进行一次后测。干预前,55.8% 的儿童表现出高营养风险。干预后,在 1 个月和 3 个月的随访中,这一比例明显下降,分别有 94.2% 和 93.6% 的儿童被归类为低风险。分析还显示,儿童的饮食行为与母亲的教育程度、家庭收入和家庭结构等因素有明显的关联。因此,网络营养教育能有效降低学龄前儿童的营养风险。研究结果强调了利用技术进行营养干预的重要性,尤其是在不同人群中。培训计划的视频简单、简短、易懂,提高了参与者对培训的兴趣,并鼓励他们定期跟进。
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引用次数: 0
A qualitative exploration of the COVID-19 pandemic on health and nutrition behaviours during the first 1000 days in Sri Lanka 对 COVID-19 大流行在斯里兰卡最初 1000 天内对健康和营养行为的定性研究。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-10-09 DOI: 10.1111/mcn.13731
Teresa R. Schwendler, Upul Senarath, Hiranya Jayawickrama, Dhammica Rowel, Noor Kawmi, Safina Abdulloeva, Chithramalee De Silva, Stephen R. Kodish

This study sought to understand reported impacts of the COVID-19 pandemic on maternal and child health and nutrition behaviours during the first 1000 days of life. This qualitative and participatory substudy was embedded within mixed methods formative research conducted during 2020–2022 across two urban, three rural and one estate sector site in Sri Lanka. Semi-structured interviews among caregivers of children aged 6–23 months (n = 34), influencers of caregivers, such as health workers (n = 37), leaders (n = 10) and pregnant women (n = 20) were conducted. Participatory workshops (n = 14) triangulated interview findings. Interview data were analyzed to identify salient themes using Dedoose. Numerical data from voting conducted in workshops were summed and triangulated with interview data. Findings suggest that the COVID-19 pandemic and imposed restrictions shaped maternal and child health and nutrition behaviours through a complex interplay of factors. Imposed restrictions and changes to the food system contributed to temporary unemployment for wage workers and reduced purchasing power to maintain food security for vulnerable households. While deciding whether to seek care, fears of infection prevented usual care-seeking decisions. Also, reduced incomes and disrupted public transportation made transport to health care facilities for antenatal care services difficult. Once women reached facilities, medical services and quality of care were negatively impacted. Implementing expanded community-based services during home visits focused on the first 1000 days and beyond was one effective strategy to maintain maternal and child health and nutrition during the early pandemic in Sri Lanka.

本研究旨在了解 COVID-19 大流行对出生后 1000 天内母婴健康和营养行为的影响。这项定性和参与性子研究是 2020-2022 年期间在斯里兰卡两个城市、三个农村和一个庄园地区开展的混合方法形成性研究的一部分。研究人员对 6-23 个月大儿童的照护者(34 人)、照护者的影响者(37 人)、领导者(10 人)和孕妇(20 人)进行了半结构化访谈。参与式研讨会(n = 14)对访谈结果进行了三角测量。使用 Dedoose 对访谈数据进行分析,以确定突出主题。对工作坊投票中的数字数据进行汇总,并与访谈数据进行三角测量。研究结果表明,COVID-19 大流行和强加的限制通过各种复杂因素的相互作用影响了母婴健康和营养行为。强加的限制和食品体系的变化导致了工资劳动者的暂时失业,并降低了弱势家庭维持食品安全的购买力。在决定是否就医时,对感染的恐惧阻碍了通常的就医决定。此外,收入减少和公共交通中断也使前往医疗机构接受产前护理服务的交通变得困难。一旦妇女到达医疗机构,医疗服务和护理质量就会受到负面影响。在家访期间实施以社区为基础的扩大服务,重点是头 1000 天及以后,这是斯里兰卡在大流行初期保持母婴健康和营养的一项有效战略。
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引用次数: 0
Prevalence and determinants of stunting and anaemia in children aged 6–23 months: A multilevel analysis from rural Ethiopia 6-23 个月儿童发育迟缓和贫血的发生率和决定因素:埃塞俄比亚农村地区的多层次分析。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-10-08 DOI: 10.1111/mcn.13736
Habtamu Guja, Mariana Belgiu, Kaleab Baye, Alfred Stein

Low- and middle-income countries shoulder the greatest burden of stunting and anaemia in children. This calls for prompt and effective intervention measures, while the contributing factors are not fully understood. This study evaluates determinants spanning from individual-, household- and community levels including agroecology and antinutrients as unique sets of predictors. Primary data were collected from 660 rural households representing the midland (ML), highland, and upper highland (UHL) agroecological zones from northern Ethiopia. The study relates several predictors to stunting and anaemia in children aged 6–23 months. We found 49.1% and 49.7% of children were stunted and anaemic, respectively. Children living in the ML are approximately twice more likely to be stunted adjusted odds ratio (AOR: 1.869; 95% CI: 1.147–3.043) than in the UHL. The risk of stunting increases by 16.3% and 41.9% for every unit increase in phytate-to-zinc and phytate-to-iron molar ratios, respectively. A 10% increase in mean aggregated crop yield was observed to reduce the likelihood of stunting occurrence by 13.6%. Households lacking non-farm income-generating opportunities, travel longer time to access the marketplace and poor health service utilisation were associated with increased risk of stunting. Low diversity of child's diet, age of the child (18–23 months) and mothers at a younger age are significantly associated with stunting. Risk of anaemia in children is high amongst households with unimproved water, sanitation, and hygiene practices, younger age (6–11 months) and mostly occurs amongst boys. Children in the ML had a 55% reduced risk of being anaemic (AOR: 0.446; 95% CI: 0.273–0.728) as compared to the UHL. Therefore, the influence of these factors should be considered to tailor strategies for reducing undernutrition in children of 6–23 months in rural Ethiopia. Interventions should go beyond the administrative boundaries into targeting agroecological variation.

中低收入国家承担着儿童发育迟缓和贫血的最大负担。这就要求我们采取及时有效的干预措施,但对造成这些问题的因素却不甚了解。本研究评估了个人、家庭和社区层面的决定因素,包括作为独特预测因素的农业生态学和抗营养素。研究从埃塞俄比亚北部中部(ML)、高地和上高地(UHL)农业生态区的 660 户农村家庭收集了原始数据。该研究将几个预测因素与 6-23 个月大儿童的发育迟缓和贫血联系起来。我们发现,分别有 49.1% 和 49.7% 的儿童发育迟缓和贫血。生活在 ML 地区的儿童发育迟缓的调整赔率(AOR:1.869;95% CI:1.147-3.043)比生活在 UHL 地区的儿童高出约两倍。植酸锌摩尔比和植酸铁摩尔比每增加一个单位,发育迟缓的风险就分别增加 16.3% 和 41.9%。作物平均总产量每增加 10%,发育迟缓发生的可能性就会降低 13.6%。缺乏非农业创收机会的家庭、前往市场的时间较长以及医疗服务利用率较低,都与发育迟缓的风险增加有关。儿童饮食多样性低、儿童年龄(18-23 个月)和母亲年龄较小与发育迟缓密切相关。在用水、环境卫生和个人卫生习惯未得到改善、儿童年龄较小(6-11 个月)且多为男孩的家庭中,儿童患贫血症的风险较高。与 UHL 相比,ML 儿童贫血的风险降低了 55%(AOR:0.446;95% CI:0.273-0.728)。因此,在制定减少埃塞俄比亚农村地区 6-23 个月儿童营养不良的策略时,应考虑这些因素的影响。干预措施应超越行政边界,以农业生态差异为目标。
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引用次数: 0
Strengthening nutrition policy and service delivery: Lessons learned from a six-country assessment of Alive and Thrive's technical assistance. 加强营养政策和服务提供:从 "活着就有希望 "技术援助六国评估中汲取的经验教训。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-10-03 DOI: 10.1111/mcn.13711
Kendra Siekmans, Sujata Bose, Jessica Escobar-DeMarco, Edward A Frongillo

Alive & Thrive (A&T) provides strategic technical assistance (TA) to develop effective policies; improve maternal, infant, and young child nutrition (MIYCN) programme design and implementation and enhance system capacity to sustain quality MIYCN service delivery at scale. A qualitative assessment was conducted using document review and stakeholder interviews (n = 79) to describe a selection of A&T's TA in six countries and systematically assess the contextual and TA process-related factors that influenced the results achieved and document the lessons learned about MIYCN TA design and implementation. To facilitate the selection of different types of TA, we classified TA into two levels of stakeholder engagement and intensity. Under the Technical Advisor TA category, we assessed A&T's support to strengthen national policy formulation, monitoring, and implementation of the International Code of Marketing of Breast-milk Substitutes. For Capacity Development TA, we assessed A&T support to scale-up maternal nutrition services and to increase strategic use of data. Factors important for TA provision included identifying and engaging with the right people, using evidence to support advocacy and decision-making, using multiple ways to strengthen capacity, developing packages of tools to support programme scale-up, and reinforcing feedback mechanisms to improve service provision and data quality. Challenges included shifts in the political context, poorly functioning health systems, and limited resources to replicate or sustain the progress made. Continued investment in evidence-based and practical TA that strengthens the institutionalization of nutrition across all stakeholders-including government, medical associations, civil society and development partners-is essential. Future TA must support governments to strengthen system capacity for nutrition, including financial and human resource gaps that hamper full scale-up.

生命与茁壮成长组织(A&T)提供战略性技术援助(TA),以制定有效的政策,改善母婴幼儿营养(MIYCN)计划的设计和实施,并提高系统能力,以持续提供高质量的母婴幼儿营养服务。通过文件审查和利益相关者访谈(n = 79)进行了定性评估,以描述 A&T 在六个国家开展的部分技术援助活动,系统评估影响所取得成果的背景因素和与技术援助过程相关的因素,并记录有关婴幼儿营养不良症技术援助设计和实施的经验教训。为便于选择不同类型的技术援助,我们将技术援助分为利益相关者参与和强度两个级别。在技术顾问类技术援助中,我们评估了 A&T 为加强《母乳代用品国际销售守则》的国家政策制定、监督和实施所提供的支持。在能力发展技术援助方面,我们评估了 A&T 为扩大孕产妇营养服务和增加数据的战略性使用所提供的支持。提供技术援助的重要因素包括:确定合适的人员并与之接触、利用证据支持宣传和决策、采用多种方式加强能力、开发支持计划推广的成套工具,以及加强反馈机制以改善服务提供和数据质量。面临的挑战包括政治环境的变化、卫生系统运转不畅以及复制或维持已取得进展的资源有限。必须继续投资于循证和实用的技术援助,以加强所有利益相关方--包括政府、医疗协会、民间社会和发展伙伴--的营养制度化。未来的技术援助必须支持政府加强营养系统的能力,包括阻碍全面推广的财政和人力资源缺口。
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引用次数: 0
Use of multiple micronutrient supplementation integrated into routine antenatal care: A discussion of research priorities 在常规产前保健中使用多种微量营养素补充剂:关于研究重点的讨论。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-10-02 DOI: 10.1111/mcn.13722
Tabassum Firoz, Jahnavi Daru, Jennifer Busch-Hallen, Özge Tunçalp, Lisa M. Rogers

Optimal maternal nutrition, including adequate intake and status of essential micronutrients, is important for the health of women and developing infants. Currently, the World Health Organization (WHO) Antenatal care recommendations for a positive pregnancy experience recommend daily iron and folic acid (IFA) supplementation as the standard of care. The use of multiple micronutrient supplements (MMS) is recommended in the context of rigorous research as more evidence was needed regarding the impact of switching from IFA supplements to MMS, including evaluation of critical clinical maternal and perinatal outcomes, acceptability, feasibility, sustainability, equity and cost-effectiveness. WHO convened a technical consultation of key stakeholders to discuss research priorities with the objective of providing guidance and clarity to donors, implementers and researchers about this recommendation. The overarching principles of the research agenda include the use of clinical indicators and impact measures that are applicable across studies and settings and the inclusion of outcomes that are important to women. Future studies should consider using standardized protocols based on current best practices to measure critical outcomes such as gestational age (GA) and birthweight (BW) in studies. As GA and BW are influenced by multiple factors, more research is needed to understand the biological impact pathways, and how initiation and considerations for timing of MMS influence these outcomes. A set of core clinical indicators was agreed upon during the technical consultation. For implementation research, the Evidence-to-Decision framework was used as a resource for discussing components of implementation research. The implementation research questions, key indicators and performance measures will depend on country-specific context and bottlenecks that require further research and improved solutions to enable the successful implementation of iron-containing supplements.

最佳的孕产妇营养,包括必需微量营养素的充足摄入和状况,对妇女和发育中婴儿的健康非常重要。目前,世界卫生组织(WHO)产前保健建议将每日补充铁和叶酸(IFA)作为标准护理。建议在严格研究的背景下使用多种微量营养素补充剂(MMS),因为需要更多证据来证明从 IFA 补充剂转向 MMS 的影响,包括对关键的临床孕产妇和围产期结果、可接受性、可行性、可持续性、公平性和成本效益的评估。世卫组织召集主要利益攸关方进行技术磋商,讨论研究重点,目的是为捐助方、实施方和研究人员提供指导,并明确这一建议。研究议程的总体原则包括使用适用于不同研究和环境的临床指标和影响措施,并纳入对妇女具有重要意义的结果。未来的研究应考虑使用基于当前最佳实践的标准化方案来测量研究中的关键结果,如胎龄(GA)和出生体重(BW)。由于胎龄和出生体重受多种因素影响,因此需要开展更多研究,以了解生物影响途径,以及 MMS 的启动和时机考虑如何影响这些结果。在技术磋商期间,各方就一套核心临床指标达成了一致。在实施研究方面,"从证据到决定 "框架被用作讨论实施研究组成部分的资源。实施研究的问题、关键指标和绩效衡量标准将取决于各国的具体情况以及需要进一步研究和改进解决方案才能成功实施含铁营养补充剂的瓶颈。
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引用次数: 0
Association between low-calorie sweetener consumption during pregnancy and child health: A systematic review and meta-analysis 孕期食用低热量甜味剂与儿童健康之间的关系:系统回顾和荟萃分析。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-09-30 DOI: 10.1111/mcn.13737
Bereket Gebremichael, Zohra S. Lassi, Mumtaz Begum, Shao Jia Zhou

We examined the association between low-calorie sweeteners (LCS) consumption during preconception, pregnancy, and breastfeeding and child health outcomes. A systematic search of electronic databases in PubMed, Embase, Cumulated Index to Nursing and Allied Health Literature, the Cochrane Library, Scopus, Web of Science, PsycINFO, ProQuest Health and Medical, ClinicalTrials.gov, and Google Scholar was conducted up to 21 September 2023. A random effects model with restricted maximum likelihood estimation was used for the meta-analysis. Seventeen eligible studies were included. The standardised mean difference (SMD) and 95% confidence interval (CI) in birth weight between those who frequently consumed LCS (≥1 serve/day) during pregnancy and those who did not consume LCS was 0.04 (0.00, 0.08) (four cohort studies). Any LCS consumption during pregnancy compared with no consumption was not associated with birth weight [SMD (95% CI) = 0.03 (−0.03, 0.08)] (four cohort studies). Any LCS consumption during pregnancy was not associated with body mass index z-scores. The weighted mean difference (95% CI) was 0.00 (−0.05, 0.06) at birth, 0.06 (−0.29, 0.40) at 6 months, −0.04 (−0.19, 0.10) at 1 year, 0.00 (−0.16, 0.17) at 3 years, and 0.10 (−0.15, 0.34) at 7 years of the child age, compared with no intake (five cohort studies). The odds of being overweight at 1 year among children exposed to LCS during pregnancy was 1.19 (OR [95% CI]: 1.19 [0.81, 1.58]) compared with unexposed children (two cohort studies). The effect sizes were not precise for all the outcomes as the 95% CI indicated the effect estimates could range from small protective to a higher risk. The effect of LCS consumption on child behaviour and cognition was inconsistent. There is not enough evidence to confirm LCS consumption during pregnancy affects birth weight and risk of overweight in children. However, frequent consumption increased birth weight and the risk of overweight at different ages, though the effects were imprecise. More robust research evidence is required as the quality of evidence is low.

我们研究了孕前、孕期和哺乳期食用低热量甜味剂(LCS)与儿童健康结果之间的关系。截至 2023 年 9 月 21 日,我们对 PubMed、Embase、Cumulated Index to Nursing and Allied Health Literature、Cochrane Library、Scopus、Web of Science、PsycINFO、ProQuest Health and Medical、ClinicalTrials.gov 和 Google Scholar 等电子数据库进行了系统检索。荟萃分析采用了限制性最大似然估计随机效应模型。共纳入了 17 项符合条件的研究。孕期经常食用低碳水化合物(≥1份/天)与不食用低碳水化合物者出生体重的标准化平均差异(SMD)和95%置信区间(CI)为0.04(0.00,0.08)(四项队列研究)。孕期食用任何低碳水化合物与不食用低碳水化合物相比,与出生体重无关[SMD (95% CI) = 0.03 (-0.03, 0.08)](四项队列研究)。孕期食用任何低碳水化合物都与体重指数 z 值无关。与未摄入相比,出生时的加权平均差异(95% CI)为 0.00 (-0.05, 0.06),6 个月时为 0.06 (-0.29, 0.40),1 岁时为 -0.04 (-0.19, 0.10),3 岁时为 0.00 (-0.16, 0.17),7 岁时为 0.10 (-0.15, 0.34)(五项队列研究)。与未摄入低氯碳酸钙的儿童相比,孕期摄入低氯碳酸钙的儿童 1 岁时超重的几率为 1.19(OR [95% CI]:1.19 [0.81, 1.58])(两项队列研究)。所有结果的效应大小并不精确,因为 95% CI 表明效应估计值可能从较小的保护作用到较高的风险不等。食用低碳水化合物对儿童行为和认知的影响并不一致。没有足够证据证实孕期食用低碳水化合物会影响出生体重和儿童超重的风险。不过,经常食用会增加出生体重和不同年龄段超重的风险,但影响并不精确。由于证据质量较低,因此需要更有力的研究证据。
{"title":"Association between low-calorie sweetener consumption during pregnancy and child health: A systematic review and meta-analysis","authors":"Bereket Gebremichael,&nbsp;Zohra S. Lassi,&nbsp;Mumtaz Begum,&nbsp;Shao Jia Zhou","doi":"10.1111/mcn.13737","DOIUrl":"10.1111/mcn.13737","url":null,"abstract":"<p>We examined the association between low-calorie sweeteners (LCS) consumption during preconception, pregnancy, and breastfeeding and child health outcomes. A systematic search of electronic databases in PubMed, Embase, Cumulated Index to Nursing and Allied Health Literature, the Cochrane Library, Scopus, Web of Science, PsycINFO, ProQuest Health and Medical, ClinicalTrials.gov, and Google Scholar was conducted up to 21 September 2023. A random effects model with restricted maximum likelihood estimation was used for the meta-analysis. Seventeen eligible studies were included. The standardised mean difference (SMD) and 95% confidence interval (CI) in birth weight between those who frequently consumed LCS (≥1 serve/day) during pregnancy and those who did not consume LCS was 0.04 (0.00, 0.08) (four cohort studies). Any LCS consumption during pregnancy compared with no consumption was not associated with birth weight [SMD (95% CI) = 0.03 (−0.03, 0.08)] (four cohort studies). Any LCS consumption during pregnancy was not associated with body mass index z-scores. The weighted mean difference (95% CI) was 0.00 (−0.05, 0.06) at birth, 0.06 (−0.29, 0.40) at 6 months, −0.04 (−0.19, 0.10) at 1 year, 0.00 (−0.16, 0.17) at 3 years, and 0.10 (−0.15, 0.34) at 7 years of the child age, compared with no intake (five cohort studies). The odds of being overweight at 1 year among children exposed to LCS during pregnancy was 1.19 (OR [95% CI]: 1.19 [0.81, 1.58]) compared with unexposed children (two cohort studies). The effect sizes were not precise for all the outcomes as the 95% CI indicated the effect estimates could range from small protective to a higher risk. The effect of LCS consumption on child behaviour and cognition was inconsistent. There is not enough evidence to confirm LCS consumption during pregnancy affects birth weight and risk of overweight in children. However, frequent consumption increased birth weight and the risk of overweight at different ages, though the effects were imprecise. More robust research evidence is required as the quality of evidence is low.</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":"21 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mcn.13737","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A landscape analysis of investors in the global breast milk substitute industry to target for advocacy 对全球母乳代用品行业的投资者情况进行分析,作为宣传目标。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-09-30 DOI: 10.1111/mcn.13721
Benjamin Wood, Ella Robinson, David McCoy, Phillip Baker, Gary Sacks

The International Code of Marketing of Breast-milk Substitutes and subsequent resolutions (the Code) was adopted to address increases in mortality and morbidity resulting from the practices of the breast-milk substitute (BMS) industry. The lack of success in ensuring company compliance with the Code has prompted advocates to consider engaging with investors to shape the governance of BMS companies. To support these efforts, this paper aimed to identify prominent investors in the global BMS industry and explore their Code-related policies and practices. Using multiple methods and data sources, we developed a novel approach to identify and rank investors in the world's leading publicly listed BMS companies. We also examined the policies and voting behaviour of a sample of investors using publicly accessible materials from 2020 to 2022. We found that a small number of large investors, led by BlackRock and Vanguard, hold a substantial share in the global BMS industry. Of the top-10 ranked investors, only Norway's Government Pension Fund (NBIM) reported policy information relating specifically to BMS marketing. Most of these large investors also opposed the sample of public health-related shareholder proposals analysed. In addition, we identified several investors that have reported engaging with BMS companies on Code-related issues, including NBIM, Pictet, and UBS, along with several potential investor targets for future advocacy efforts, including some North American public pension funds. The inclusion of Code-related issues as part of broader policies, disclosures and regulations related to environmental, social and governance oriented investment warrants increased attention.

国际母乳代用品销售守则》及其后续决议(《守则》)的通过是为了解决母乳代用品(BMS)行业的做法导致死亡率和发病率上升的问题。在确保公司遵守《准则》方面缺乏成功经验,这促使倡导者考虑与投资者合作,以塑造母乳代用品公司的管理模式。为了支持这些努力,本文旨在确定全球母乳代用品行业的知名投资者,并探讨他们与《准则》相关的政策和实践。利用多种方法和数据源,我们开发了一种新方法来识别全球领先的 BMS 上市公司的投资者并对其进行排名。我们还利用 2020 年至 2022 年期间可公开获取的资料,对抽样投资者的政策和投票行为进行了研究。我们发现,以贝莱德(BlackRock)和先锋(Vanguard)为首的少数大型投资者在全球 BMS 行业占有相当大的份额。在排名前十的投资者中,只有挪威政府养老基金(NBIM)报告了专门与 BMS 营销相关的政策信息。这些大型投资者中的大多数也反对所分析的与公共健康相关的股东提案样本。此外,我们还发现一些投资者曾报告与 BMS 公司就《准则》相关问题进行过接触,其中包括 NBIM、Pictet 和 UBS,以及一些潜在的投资者目标(包括一些北美公共养老基金)。将《准则》相关问题作为与环境、社会和治理导向投资相关的更广泛政策、披露和法规的一部分,值得更多关注。
{"title":"A landscape analysis of investors in the global breast milk substitute industry to target for advocacy","authors":"Benjamin Wood,&nbsp;Ella Robinson,&nbsp;David McCoy,&nbsp;Phillip Baker,&nbsp;Gary Sacks","doi":"10.1111/mcn.13721","DOIUrl":"10.1111/mcn.13721","url":null,"abstract":"<p>The International Code of Marketing of Breast-milk Substitutes and subsequent resolutions (the Code) was adopted to address increases in mortality and morbidity resulting from the practices of the breast-milk substitute (BMS) industry. The lack of success in ensuring company compliance with the Code has prompted advocates to consider engaging with investors to shape the governance of BMS companies. To support these efforts, this paper aimed to identify prominent investors in the global BMS industry and explore their Code-related policies and practices. Using multiple methods and data sources, we developed a novel approach to identify and rank investors in the world's leading publicly listed BMS companies. We also examined the policies and voting behaviour of a sample of investors using publicly accessible materials from 2020 to 2022. We found that a small number of large investors, led by BlackRock and Vanguard, hold a substantial share in the global BMS industry. Of the top-10 ranked investors, only Norway's Government Pension Fund (NBIM) reported policy information relating specifically to BMS marketing. Most of these large investors also opposed the sample of public health-related shareholder proposals analysed. In addition, we identified several investors that have reported engaging with BMS companies on Code-related issues, including NBIM, Pictet, and UBS, along with several potential investor targets for future advocacy efforts, including some North American public pension funds. The inclusion of Code-related issues as part of broader policies, disclosures and regulations related to environmental, social and governance oriented investment warrants increased attention.</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":"21 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mcn.13721","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using formative research to enhance our understanding of implementation contexts: Preparing for a trial of maternal nutrition interventions 利用形成性研究加强我们对实施环境的了解:为孕产妇营养干预试验做准备。
IF 2.8 2区 医学 Q3 NUTRITION & DIETETICS Pub Date : 2024-09-29 DOI: 10.1111/mcn.13639
Andrew L. Thorne-Lyman, Anna Kalbarczyk, Alison Tumilowicz, Parul Christian, Kaosar Afsana
<p>Traditionally, nutrition interventions during pregnancy in low- and middle-income countries (LMICs) have received less attention than interventions focused on child nutrition. However, a solid body of evidence suggests that interventions to address micronutrient and macronutrient deficiencies during pregnancy could significantly improve both maternal and neonatal health along with foetal and child growth (Koivu et al., <span>2023</span>; World Health Organization [WHO], <span>2016</span>; Zavala et al., <span>2022</span>) and need to be delivered at scale.</p><p>The WHO guidelines for a healthy pregnancy include several evidence-based nutrition interventions. Along with iron-folic acid (IFA), calcium and dietary education, the guidelines currently recommend multiple micronutrient supplementation (MMS) as a replacement for IFA ‘in the context of rigorous research’ and balanced energy and protein (BEP) supplementation specifically for contexts of high undernutrition (WHO, <span>2016</span>).</p><p>The importance of finding ways to optimise the delivery of nutrition interventions to pregnant women has been highlighted in many recent reviews including the Lancet Series on Maternal and Child Nutrition (Heidkamp et al., <span>2021</span>; Young & Ramakrishnan, <span>2020</span>). A number of implementation research efforts are underway in countries throughout the world piloting MMS as a replacement for IFA implemented through antenatal care (ANC) (Horino et al., <span>2021</span>; King et al., <span>2020</span>). In contrast, it is less clear how BEP supplementation in pregnancy should be implemented as few examples of BEP supplementation programmes in pregnancy exist outside of emergency settings. This may be due to the high cost of food and the unique challenges of working with food commodities including storage and distribution.</p><p>The WHO specifically recommends a population-based approach for BEP supplementation, focused on areas in which the population prevalence of low body-mass index (<18.5 kg/m<sup>2</sup>) is greater than 20% (WHO, <span>2016</span>). Only two countries (Bangladesh and India) meet this criteria at a national level (Christian et al., <span>2020</span>), although many countries have subnational regions that exceed this prevalence (Victora et al., <span>2021</span>). While WHO guidelines do not presently recommend the identification and supplementation of individual undernourished pregnant women, it has been argued that such an approach might optimise the benefits and costs of BEP supplementation (Christian et al., <span>2020</span>).</p><p>Other than India, with its large national ICDS programme, Bangladesh is one of the few countries with experience implementing a large-scale nutrition programme that included food supplementation of pregnant women. The Bangladesh Integrated Nutrition Programme (BINP) and National Nutrition Project (NNP), implemented from 1995 to 2006 was a large programme in rural Bangladesh that
Lama、Khatry 等人,2022 年;Lama、Moore 等人,2022 年)也强调了该产品的可接受性,补充了尼泊尔对 BEP 产品(包括另一种即用糊剂)进行的其他可行性和依从性研究的积极结果。鉴于 BEP 在这种情况下的接受程度,BEP 很可能会受到其他人群的欢迎,并可能有助于提高其他共同提供的干预措施的效果,其中可能包括产前保健本身以及营养教育。2021 年《柳叶刀》母婴营养丛书强调,需要开展更多 "如何 "研究,以找到提供已知有效干预措施的方法(Shekar 等人,2021 年)。开展形成性研究以了解引入干预措施的社会文化和经济背景,包括设计基于社区的有效性试验,可提供关键信息,有助于在有效性试验中以及最终在营养计划中最大限度地吸收干预措施(Tumilowicz 等人,2015 年)。所有作者均提供了重要反馈意见,并批准了最终版本。作者声明无利益冲突。
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引用次数: 0
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Maternal and Child Nutrition
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