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UNDERREPRESENTATION OF OLDER PERSONS IN CLINICAL TRIALS 老年人在临床试验中的代表性不足
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.29400/tjgeri.2023.349
Yeşim GÖKÇE KUTSAL, Önder İLGİLİ, Murat KOÇ, C.Sercan ÖZYURT
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引用次数: 0
Examination of mental symptoms, anger, and death anxiety in elderly cancer patients 老年癌症患者精神症状、愤怒和死亡焦虑的检查
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.29400/tjgeri.2023.357
Gözde BACIK YAMAN, Erkan KAYIKÇIOĞLU, Çiçek HOCAOĞLU
Introduction: Cancer is a disease that changes a person’s expectations about death and life. The needs of elderly cancer patients differ according to other age groups. This study aims to reveal the relationship between psychological symptoms and death anxiety and anger expression in elderly patients diagnosed with cancer. Methods: Scales assessing anxiety, depression, death anxiety, and anger were administered to patients over 65 years of age diagnosed with cancer. Patients were asked about the type of cancer, when it was diagnosed, and what treatment they received. They were also asked with whom they lived and with whom they came to check. Results: Of the 201 patients included, 18.9% were diagnosed with anxiety disorder and 17.9% with depression. A high positive statistically significant correlation existed between anxiety and depression symptoms (r=0.755, p<0.001). There was a moderately positive and statistically significant correlation between anxiety symptoms and death anxiety (r=0.599, p<0.001) and state anger (r=0.504, p<0.001). A one-unit increase in state anger score increases the risk of developing depressive symptoms by 11%, while a one-unit increase in death anxiety increases the same risk by 10.6%. When we analyzed according to cut-off values, 124 (61.7% of the whole sample), participants had high death anxiety. Conclusion: Psychological symptoms in elderly cancer patients seem to be associated with death anxiety and anger. Death anxiety should not be considered a natural consequence of getting cancer. Screening for mental symptoms during stressful times can help identify psychological needs and provide targeted psychological support for the elderly. Keywords: Mental Health; Aged; Anger; Neoplasms.
简介:癌症是一种改变一个人对死亡和生命的期望的疾病。老年癌症患者的需求因其他年龄组而异。本研究旨在揭示老年癌症患者心理症状与死亡焦虑和愤怒表达的关系。方法:对65岁以上诊断为癌症的患者进行焦虑、抑郁、死亡焦虑和愤怒量表评估。患者被问及癌症的类型,何时被诊断出来,以及他们接受了什么治疗。他们还被问及和谁住在一起,和谁一起来检查。结果:在纳入的201例患者中,18.9%诊断为焦虑症,17.9%诊断为抑郁症。焦虑与抑郁症状之间存在高度正相关(r=0.755, p<0.001)。焦虑症状与死亡焦虑(r=0.599, p < 0.001)和状态愤怒(r=0.504, p < 0.001)呈正相关,且有统计学意义。状态愤怒得分每增加一个单位,出现抑郁症状的风险就会增加11%,而死亡焦虑得分每增加一个单位,同样的风险就会增加10.6%。当我们根据临界值进行分析时,124名(占整个样本的61.7%)参与者有高度的死亡焦虑。结论:老年癌症患者的心理症状似乎与死亡焦虑和愤怒有关。死亡焦虑不应该被认为是患癌症的自然结果。在压力时期筛查精神症状有助于确定心理需求,并为老年人提供有针对性的心理支持。关键词:心理健康;岁的;愤怒;肿瘤。
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引用次数: 0
AGE-RELATED DIFFERENCES IN PROSPECTIVE MEMORY: TURKISH VIRTUAL WEEK (VW-TR) 前瞻性记忆的年龄相关差异:土耳其虚拟周(vw-tr)
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.29400/tjgeri.2023.351
Gün PAKYÜREK, Banu CANGÖZ TAVAT
Introduction: Prospective memory, which involves remembering intended future actions, is a vital function in terms of autonomy, quality of life, and everyday functioning. The primary aim of this study is to examine how aging affects prospective memory performance; its secondary aim is to adapt a laboratory-based prospective memory task, Virtual Week, to the Turkish culture and investigate its efficacy across young and old age groups. Materials and Method: The study was conducted with 60 young (18–25 years) and 60 old (60–87 years) participants. Participants were included based on their results on cognitive screening tests (Montreal Cognitive Assessment, Activities of Daily Living Scale, Geriatric Depression Scale, and the Beck Depression Inventory). In addition, the Stroop and Trail Making tests were administered to measure executive functions. Finally, the laboratory-based prospective memory task Virtual Week was performed. Results: Virtual Week has been adapted to Turkish culture and shown to be reliable (Spearman–Brown: 0.82). ANOVA was conducted to analyze the effect of aging on the Virtual Week task, and the results showed that young adults were more successful than older adults in prospective memory tasks (p < .05). Conclusion: The results support the theory of the aging paradox in prospective memory, which suggests that older adults exhibit lower performance in laboratory-based prospective memory tasks. The findings are discussed in the context of the relevant literature. Keywords: Memory; Cognitive Aging; Executive Function; Young Adult; Aged.
前瞻记忆,包括记住预期的未来行为,在自主性、生活质量和日常功能方面是一个至关重要的功能。本研究的主要目的是研究年龄如何影响前瞻性记忆表现;它的第二个目标是适应一个基于实验室的前瞻性记忆任务,虚拟周,土耳其文化,并调查其在年轻人和老年人群体的功效。材料与方法:研究对象为60名青年(18-25岁)和60名老年人(60 - 87岁)。参与者是根据他们的认知筛选测试(蒙特利尔认知评估、日常生活活动量表、老年抑郁量表和贝克抑郁量表)的结果纳入研究的。此外,还进行了Stroop和Trail Making测试来测量执行功能。最后,进行基于实验室的前瞻记忆任务Virtual Week。结果:虚拟周已适应土耳其文化,并证明是可靠的(Spearman-Brown: 0.82)。通过方差分析分析年龄对虚拟周任务的影响,结果显示年轻人比老年人在前瞻性记忆任务中更成功(p <. 05)。结论:研究结果支持了前瞻记忆的衰老悖论理论,即老年人在基于实验室的前瞻记忆任务中表现较差。研究结果在相关文献的背景下进行了讨论。关键词:记忆;认知老化;执行功能;年轻的成年人;岁的。
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引用次数: 0
Treatment Outcomes in Breast Cancer Patients Aged 65 and Above 65岁及以上乳腺癌患者的治疗效果
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.29400/tjgeri.2023.358
Rahşan HABİBOĞLU, İlknur KAYALI, İrem SARICANBAZ
Introduction: Despite the increasing number of elderly patients with breast cancer, optimal treatment options remain limited. This study aims to evaluate the clinical characteristics, treatment approaches, and survival outcomes of the patient group aged 65 and above who were treated for breast cancer at our clinic. Materials and Methods: The data of breast cancer patients aged 65 and above who received treatment and follow-up at our clinic between 2012 and 2018 were retrospectively analyzed. Overall survival and disease-free survival analyses were performed using Kaplan-Meier analysis, and comparisons were conducted using the log-rank test. Results: A total of 108 elderly female patients with breast cancer were included in the study. The median follow-up duration was 79.75 months (6.64 years), with a maximum follow-up of 133.49 months (11.12 years). At the end of this period, 88 patients (81.48%) were still alive. The 3-year overall survival rate was 93.5%, and the 5-year overall survival rate was 86.1%. The 3-year disease-free survival rate was 91.6%, and the 5-year disease-free survival rate was 88.7%. Conclusion: When making treatment decisions for elderly breast cancer patients, factors such as performance status, comorbidities, toxicity, and post-treatment quality of life should be carefully considered alongside age. Treatment decisions should be based on comprehensive evaluations taking these factors into account. Keywords: Breast Neoplasms; Treatment Outcome; Aged; Mastectomy; Drug Therapy; Radiotherapy.
导读:尽管老年乳腺癌患者数量不断增加,但最佳治疗方案仍然有限。本研究旨在评价65岁及以上患者在我院接受乳腺癌治疗的临床特点、治疗方法及生存结局。材料与方法:回顾性分析我院2012年至2018年65岁及以上接受治疗及随访的乳腺癌患者资料。采用Kaplan-Meier分析进行总生存期和无病生存期分析,采用log-rank检验进行比较。结果:共纳入108例老年女性乳腺癌患者。中位随访时间79.75个月(6.64年),最长随访时间133.49个月(11.12年)。随访结束时,88例患者(81.48%)仍然存活。3年总生存率为93.5%,5年总生存率为86.1%。3年无病生存率为91.6%,5年无病生存率为88.7%。结论:在对老年乳腺癌患者进行治疗决策时,除考虑年龄外,还应认真考虑运动状态、合并症、毒性、治疗后生活质量等因素。治疗决定应基于综合评估,考虑到这些因素。关键词:乳腺肿瘤;治疗效果;岁的;乳房切除术;药物治疗;放射治疗。
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引用次数: 0
Cognitive and motor performances in dual tasks in older adults with chronic neck pain: A randomized controlled clinical trial 老年慢性颈部疼痛患者在双重任务中的认知和运动表现:一项随机对照临床试验
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.29400/tjgeri.2023.353
Aydın Sinan APAYDIN, Emre SOYLEMEZ
Aim: There is limited information on dual-task performance in older individuals with chronic neck pain. This study aims to investigate cognitive and motor performances during dual tasks in older adults with chronic neck pain. Methods: Thirty-five older adults with chronic neck pain and 35 older adults without neck pain were included in the study. The timed up and go test evaluated individuals’ single-task performance. To assess the dual-task performances of the groups, the individuals were given motor and cognitive (forward and backward digit span) tasks simultaneously with the timed up and go test. During cognitive dual-task, the cognitive performances of individuals were evaluated and the duration of their timed up and go test was recorded. Results: There was no difference between the groups in terms of single-task timed up and go test (p >0.05). There was also no difference between the groups in terms of cognitive-forward and cognitive-backward (p >0.05). However, cognitive performance of the chronic neck pain group during dual-task was worse than that of the control group (p <0.05). Additionally, the motor dual-task of older adults in the chronic neck pain group was worse than the control group (p <0.05). Conclusion: Older adults with chronic neck pain struggle more in motor dual-task situations than asymptomatic older adults. Therefore, gait assessment with a motor dual task should be performed for older adults with chronic neck pain. In addition, during cognitive dual-task conditions, the cognitive performance of older adults should be evaluated in addition to their gait performance. Keywords: Aged; Gait; Neck Pain; Postural Balance; Task Performance and Analysis.
目的:关于慢性颈部疼痛老年人双任务表现的信息有限。本研究旨在探讨慢性颈部疼痛的老年人在双重任务中的认知和运动表现。方法:选取35例慢性颈痛老年人和35例无颈痛老年人作为研究对象。计时出发测试评估个体的单一任务表现。为了评估两组人的双重任务表现,研究人员在进行计时up and go测试的同时,给这些人分配了运动和认知任务(向前和向后的数字跨度)。在认知双任务过程中,对个体的认知表现进行评估,并记录个体的上、下测试时间。结果:单任务计时up和go测试两组间差异无统计学意义(p >0.05)。两组在认知前向和认知后向方面也无差异(p >0.05)。而慢性颈痛组双任务认知表现较对照组差(p <0.05)。此外,慢性颈部疼痛组老年人运动双任务表现差于对照组(p <0.05)。结论:慢性颈部疼痛的老年人在运动双任务情境下比无症状的老年人更挣扎。因此,对于患有慢性颈部疼痛的老年人,应该进行运动双重任务的步态评估。此外,在认知双任务条件下,除了评估老年人的步态表现外,还应评估老年人的认知表现。关键词:年龄;步态;颈部疼痛;姿势平衡;任务绩效和分析。
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引用次数: 0
RISK FACTORS FOR PROLONGED INTENSIVE CARE UNIT STAYS IN ELDERLY PATIENTS AFTER CARDIAC SURGERY: A RETROSPECTIVE OBSERVATIONAL STUDY 老年患者心脏手术后重症监护病房延长的危险因素:一项回顾性观察性研究
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.29400/tjgeri.2023.359
Bedih BALKAN, Mücahit POLAT, Lokman YALÇIN, Taner İYİGÜN, Barış TİMUR
Introduction: With the increase in life expectancy and developments in surgical and anesthetic techniques, intensive care follow-up, and treatment methods, the number of patients undergoing open-heart surgery has increased. Methods: The clinical files of 220 patients who underwent cardiovascular surgery were retrospectively reviewed. The patients were divided into two groups: group 1 (those who stayed for one day or less) and group 2 (those who stayed for more than one day). In addition, the reason for hospitalization for five days or more was investigated. The effect of patient variables on the length of stay in the intensive care unit was investigated by logistic regression analysis. Results: Hemoglobin values, ejection fraction values, and intensive care unit hospitalizations were significantly lower (p<0.05) than those in the group with intensive care unit hospitalizations of <24 h. The sodium value was significantly higher (p<0.05) in the group with intensive care unit hospitalizations >24 h than in the group with intensive care unit hospitalizations <24 h. The pacemaker requirement rate in the group with intensive care unit hospitalizations >24 h was significantly (p<0.05) higher than the group with intensive care unit hospitalizations < 24 h. The sinus rhythm in the group with intensive care unit hospitalizations >24 h was significantly lower (p<0.05) than that in the group with intensive care unit hospitalizations <24 h. Intensive care transfusion of erythrocyte suspension, fresh frozen plasma, and platelet suspension were significantly higher (p<0.05) in the group with intensive care unit hospitalizations >24 h than in the group with intensive care unit hospitalizations <24 h. Conclusion: In our study; We found that factors such as preoperative low ejection fraction (EF), hypernatremia, female gender, inotrope requirement, delirium, extubation time, intraoperative-postoperative transfusion, drainage revision affect the length of stay in the intensive care unit In the intraoperative period, methods to protect myocardial and kidney functions and provide hemostasis bleeding control reduce the duration of intensive care hospitalization Keywords: Thoracic Surgery; Length of Stay; Critical Care; Aging.
导读:随着预期寿命的延长以及外科和麻醉技术、重症监护随访和治疗方法的发展,接受心脏直视手术的患者数量有所增加。方法:回顾性分析220例心血管手术患者的临床资料。将患者分为两组:1组(住院1天及以下)和2组(住院1天以上)。此外,还调查了住院5天或更长时间的原因。采用logistic回归分析探讨患者变量对重症监护病房住院时间的影响。结果:血红蛋白值,射血分数值和重症监护室住院(术中;0.05)显著低于那些在重症监护室住院的集团& lt; 24 h。钠值明显高于(术中;0.05)组和重症监护室住院在24小时比组和重症监护室住院& lt; 24 h。该集团的起搏器需求率与重症监护室住院在24小时显著(术中;0.05)高于组重症监护病房住院情况<24 h重症监护室组窦性心律显著低于重症监护室组(p<0.05),重症监护室组输血红细胞悬液、新鲜冷冻血浆、血小板悬液显著高于重症监护室组(p<0.05)。我们发现术前低射血分数(EF)、高钠血症、女性、肌力需求、谵妄、拔管时间、术中术后输血、引流改道等因素影响患者在重症监护病房的住院时间。术中采取保护心肌、肾功能、止血控制等措施可减少重症监护住院时间。关键词:胸外科;逗留时间;急救护理;老化。
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引用次数: 0
USING THE ROTTERDAM CT SCORE TO PREDICT OUTCOMES OF HEAD INJURIES IN THE GERIATRIC POPULATION 使用鹿特丹ct评分预测老年人群头部损伤的结果
IF 0.3 4区 医学 Q4 Medicine Pub Date : 2021-09-27 DOI: 10.31086/TJGERI.2021.239
P. Ozturk, U. Ozturk
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引用次数: 0
The Effects of Renal Insufficiency and Age on Mortality in Geriatric Patients with Non-ST-Segment Elevation Myocardial Infarction 肾功能不全和年龄对老年非st段抬高型心肌梗死患者死亡率的影响
IF 0.3 4区 医学 Q4 Medicine Pub Date : 2021-09-27 DOI: 10.31086/TJGERI.2021.228
Pınar D Gündoğmuş
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引用次数: 1
Health Science Students Perceptions and Awareness of Elder Abuse and Neglect 健康科学学生对虐待和忽视老人的认知和意识
IF 0.3 4区 医学 Q4 Medicine Pub Date : 2021-03-29 DOI: 10.31086/TJGERI.2021.205
B. B. Kahraman, Ülkü Polat, N. Gürhan
Results: Although the majority of the students (92.7%) have indicated that they were aware of the concept of elderly abuse and neglect, it was observed that the students couldn’t define the concept of elderly abuse either comprehensively or clearly. It was determined in our study that the type of abuse mostly known by these students was physical abuse, and thus their knowledge about abuse was insufficient. It was observed that the number of students who receive education about this concept was higher in the nursing department when compared to the other departments (p<0.05).
结果:绝大多数学生(92.7%)表示对虐待老人和忽视老人的概念有所了解,但对虐待老人的概念并不能进行全面、清晰的界定。在我们的研究中确定,这些学生最了解的虐待类型是身体虐待,因此他们对虐待的认识不足。观察发现,护理科接受这一概念教育的学生人数高于其他科室(p<0.05)。
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引用次数: 1
Clinical findings and prognosis of hospitalized elderly covid-19 patients 住院老年covid-19患者临床表现及预后分析
IF 0.3 4区 医学 Q4 Medicine Pub Date : 2021-03-29 DOI: 10.31086/TJGERI.2021.194
Ö. Bozan, Ş. Atiş, B. Çekmen, Mehmet Taylan Koçer, Y. Koca, Edip Burak Karaaslan, Mücahit Şentürk, F. Şimşek, A. Kalkan
Background: SARS-CoV-2 has caused an outbreak all over the World Age is the most important factor for mortality However, it is not known exactly why SARS-CoV-2 infections are more severe and fatal in the elderly population We examined the clinical course and the causes of increasing mortality in all hospitalized patients diagnosed with COVID-19 over 65 years of age Methods: Hospitalized elderly patients diagnosed with COVID-19 were examined in this retrospective observational study The blood results, length of stay, comorbid diseases, admission symptoms, clinical results and demographic data of the patients were recorded It was examined whether there was a significant difference between surviving and non-surviving patients in terms of comorbid diseases and symptoms The effects of these parameters on the 30-day mortality alone were investigated Results: A total of 263 patients (125 males) were included in the study Cough (53 2%) followed by dyspnea (35 7%) were the two most common symptoms There was no statistically significant difference age or sex distribution between survivor and nonsurvivor patients Patients with dyspnea had a significantly lower survival rate compared to patients who did not have dyspnea at presentation and patients who have chronic obstructive pulmonary disease and cerebrovascular disease were associated with a significantly increased risk of mortality Conclusions: It has been shown that there is a significant increase in the risk of mortality in COVID-19 patients with chronic obstructive pulmonary disease and cerebrovascular diseases Additionally, Dyspnea, as an admission symptom, were found to have an effect on mortality and clinical outcomes in our study
背景:年龄是导致死亡的最重要因素,然而,为什么SARS-CoV-2感染在老年人群中更为严重和致命尚不清楚。我们对所有65岁以上诊断为COVID-19的住院患者的临床病程和死亡率增加的原因进行了调查。本回顾性观察性研究对诊断为COVID-19的住院老年患者进行检查,记录患者的血检结果、住院时间、合并症、入院症状、临床结果及人口学资料,检查存活患者与非存活患者在合并症和症状方面是否存在显著差异,并单独考察这些参数对30天死亡率的影响。研究共纳入263例患者(125名男性),咳嗽(53.2%)和呼吸困难(35.7%)是两种最常见的症状,幸存者和非幸存者患者的年龄和性别分布无统计学差异。与首发时无呼吸困难的患者相比,呼吸困难患者的生存率明显较低,患有慢性阻塞性肺疾病和脑血管疾病的患者与A相关结论:已有研究表明COVID-19合并慢性阻塞性肺疾病和脑血管疾病患者的死亡风险显著增加,并且我们的研究发现呼吸困难作为入院症状对死亡率和临床结局有影响
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引用次数: 3
期刊
Turkish Journal of Geriatrics-Turk Geriatri Dergisi
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