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Predictive Utility of Four Instrumental Activities of Daily Living Assessments and Cognitive Status Changes Among Cognitively In-Tact Older Adults. 四种工具性日常生活活动评估的预测效用与认知障碍老年人的认知状态变化。
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-12-01 Epub Date: 2024-11-09 DOI: 10.1177/08982643241297193
Christine B Phillips, Ava McVey, Briana N Sprague, Kalvry Cooper, Abigail T Stephan, Lesley A Ross

PurposeTo examine the factor structure and predictive utility of four instrumental activities of daily living (IADL) measures to identify cognitive status changes among older adults enrolled in the ACTIVE Trial.Major FindingsExtracted factors represented IADL instruments. Baseline performance on the Everyday Problems Test (EPT) predicted 5-year MMSE scores (est. = .08, p < .001), adjusting for demographic and health covariates, baseline MMSE, self-reported IADL function, and the performance-based Observed Tasks of Daily Living and Timed Instrumental Activities of Daily Living assessments. For each 1-point increase in baseline EPT financial performance, the odds of cognitive impairment decreased by 26%.ConclusionsIADL functional domains were not interchangeable across instruments. The EPT demonstrated better predictive utility compared to other instruments for detecting subsequent cognitive decline/impairment. This is a useful step in developing effective tools to detect early functional deficits indicating subsequent clinical impairment. Advanced Cognitive Training for Independent and Vital Elderly Trial (ACTIVE), NCT00298558, https://clinicaltrials.gov/study/NCT00298558.

目的:研究四种工具性日常生活活动(IADL)测量方法的因子结构和预测效用,以确定参加 ACTIVE 试验的老年人的认知状况变化:提取的因子代表了 IADL 工具。日常问题测试(EPT)的基线表现预测了5年的MMSE得分(est. = .08,p < .001),调整了人口统计学和健康协变量、基线MMSE、自我报告的IADL功能以及基于表现的日常生活观察任务和定时日常生活工具活动评估。基线EPT财务表现每提高1分,认知障碍的几率就会降低26%:不同工具的 IADL 功能域不可互换。与其他工具相比,EPT 在检测后续认知能力下降/受损方面具有更好的预测效用。这对于开发有效工具以检测早期功能障碍、预示后续临床损害非常有用。独立和活力老人高级认知训练试验(ACTIVE),NCT00298558,https://clinicaltrials.gov/study/NCT00298558。
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引用次数: 0
Use of Medications With Somnolence Adverse Effects and Somnolence Symptoms Among Older Adults in the U.S. 美国老年人使用具有嗜睡不良反应和嗜睡症状的药物情况
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-12-01 Epub Date: 2024-11-26 DOI: 10.1177/08982643241298734
Jocelyn Wilder, Diane Lauderdale, Dima M Qato

ObjectivesNearly half of older adults experience somnolence, but the link between medications with somnolence as an adverse effect and somnolence is unclear. This study investigated the association between polypharmacy and somnolence symptoms (excessive sleepiness or long sleep duration).MethodsData from the National Social Life, Health, and Aging Project (NSHAP) 2010-2011 was used to examine the concurrent use of medications with potential somnolence as an adverse effect and the prevalence of somnolence symptoms.ResultsAmong the 2638 older adults (mean, 71 years), 49.0% used medications with potential somnolence adverse effects. The adjusted prevalence of somnolence symptoms was significantly higher among those using three or more medications (58%) than those not using such medications (31.2%) (difference, 20.4%; 95% CI 12.5, 28.4).DiscussionIn this cross-sectional study, medications with somnolence as a potential adverse effect were commonly used, and the findings suggest a link between polypharmacy and the increased risk of somnolence symptoms.

目的:近一半的老年人会出现嗜睡症状,但以嗜睡为不良反应的药物与嗜睡之间的关系尚不清楚。本研究调查了多种药物治疗与嗜睡症状(过度嗜睡或睡眠时间过长)之间的关系:方法:利用 2010 至 2011 年国家社会生活、健康和老龄化项目(NSHAP)的数据,研究同时使用可能会导致嗜睡不良反应的药物与嗜睡症状的发生率:结果:在 2638 名老年人(平均 71 岁)中,49.0% 的人服用了可能会引起嗜睡不良反应的药物。经调整后,使用三种或三种以上药物者(58%)的嗜睡症状发生率明显高于未使用此类药物者(31.2%)(差异为 20.4%;95% CI 为 12.5 至 28.4):讨论:在这一横断面研究中,将嗜睡作为潜在不良反应的药物是常用药物,研究结果表明,多药治疗与嗜睡症状风险增加之间存在联系。
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引用次数: 0
Health Experiences of LGBTQ+ People Living With Dementia and Their Care Partners: A Scoping Review of Research and Policy. LGBTQ+ 痴呆症患者及其护理伙伴的健康体验:研究与政策范围综述》。
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-12-01 Epub Date: 2024-11-10 DOI: 10.1177/08982643241299478
Melissa Harris-Gersten, Ames Simmons, Stephanie Hendren, Jennifer May

ObjectivesThis scoping review aimed to synthesize research on the health experiences of LGBTQ+ people living with dementia (PLWD) and their caregivers, and the impact of health policies on this population.MethodsSix databases were searched for research studies and policy literature. Titles, abstracts, and full texts were reviewed by a three-member team. Data was extracted and thematically analyzed. Feedback from 7 LGBTQ+ adults was collected through a community consultation session.ResultsA total of 9257 unique research and 945 policy citations were identified, of which 60 research and 19 policy papers were reviewed. Nine research studies and ten policy papers met eligibility criteria. Themes emerged through the analysis of research findings, the community listening session, and policy findings.DiscussionFuture work needs to disentangle the impact of policies on the health experiences of this population. Dementia-specific and LGBTQ+ inclusive services and policies are needed to address growing health disparities.

研究目的本范围综述旨在综合有关 LGBTQ+ 痴呆症患者(PLWD)及其照顾者的健康经历的研究,以及健康政策对这一人群的影响:方法:在六个数据库中搜索研究报告和政策文献。三人小组对标题、摘要和全文进行了审阅。提取数据并进行专题分析。通过社区咨询会收集了 7 名 LGBTQ+ 成人的反馈意见:结果:共确定了 9257 篇研究论文和 945 篇政策论文,其中 60 篇研究论文和 19 篇政策论文经过了审阅。9 项研究和 10 篇政策论文符合资格标准。通过对研究成果、社区听证会和政策成果的分析,得出了一些主题:讨论:未来的工作需要厘清政策对这一人群健康体验的影响。需要制定专门针对痴呆症和包容 LGBTQ+ 的服务和政策,以解决日益增长的健康差异问题。
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引用次数: 0
Comparing the Health Status of Immigrant and New Zealand-Born Older Adults in Aotearoa New Zealand: The Role of Socioeconomic Position. 比较新西兰奥特亚罗瓦地区移民和新西兰出生的老年人的健康状况:社会经济地位的作用》。
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-12-01 Epub Date: 2024-10-18 DOI: 10.1177/08982643241276268
Ágnes Szabó, Rachel E Goodin

ObjectivesThe study investigated the health status of older migrants relative to their New Zealand-born peers. We adopted a holistic view of health (physical, mental, and social) and a structural approach to health disparities based on migrant status and socioeconomic position.MethodsUsing case-control matching based on age, gender, and education, the health status of 357 older migrants and 357 New Zealand-born older adults was compared.ResultsOlder migrants reported significantly poorer social health. Health inequities were patterned by socioeconomic status. Working class older migrants had significantly poorer physical, mental, and social health than their New Zealand-born peers. Inequities in social wellbeing persisted even at the upper end of the social gradient.DiscussionMigrant background is an important social determinant of health in older age. The reduced social wellbeing of economically advantaged migrants highlights vulnerabilities regardless of socioeconomic position and the need for targeted social policies.

研究目的本研究调查了老年移民相对于新西兰出生的同龄人的健康状况。我们采用了整体健康观(身体、精神和社会),并根据移民身份和社会经济地位对健康差异采取了结构性方法:通过基于年龄、性别和教育程度的病例对照匹配,比较了 357 名老年移民和 357 名新西兰出生的老年人的健康状况:结果:老年移民的社会健康状况明显较差。社会经济地位造成了健康不平等。工薪阶层老年移民的身体、精神和社会健康状况明显差于新西兰出生的同龄人。即使在社会梯度的高端,社会福利方面的不平等依然存在:讨论:移民背景是老年人健康的一个重要社会决定因素。经济条件优越的移民社会福利的降低凸显了他们的脆弱性,无论其社会经济地位如何,都需要有针对性的社会政策。
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引用次数: 0
Number of Chronic Conditions and Death Anxiety Among Older Adults in Rural China: A Longitudinal Study in Anhui Province. 中国农村老年人慢性病数量与死亡焦虑:安徽省的一项纵向研究
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-12-01 Epub Date: 2024-10-03 DOI: 10.1177/08982643241289516
Jin Guo, Andrew Wister, Barbara Mitchell, Shuzhuo Li

Objectives: Death anxiety is feelings of worry and fear regarding death. This study explored the effect of number of chronic conditions on death anxiety in older adults and the moderating effect of age. Methods: This study used the fifth, sixth, seventh, and eighth waves of longitudinal data (2012-2021) collected in Anhui, China (5014 person-year observations). A mixed linear model was used to examine the effect of number of chronic conditions on death anxiety and the moderating effect of age. Results: The number of chronic conditions showed an inverted U-shaped relationship with death anxiety, with death anxiety being lower in older adults with older age. As age increased, the U-shaped curve became flatter, and the extremes shifted to the right. Discussion: Particular attention should be given to younger older adults with chronic conditions to help them recover earlier from the negative impact by providing information and counseling about their chronic conditions.

目的:死亡焦虑是指对死亡的担忧和恐惧。本研究探讨了慢性疾病数量对老年人死亡焦虑的影响以及年龄的调节作用。研究方法本研究使用了在中国安徽收集的第五、第六、第七和第八波纵向数据(2012-2021 年)(5014 人年观察值)。研究采用混合线性模型来检验慢性疾病数量对死亡焦虑的影响以及年龄的调节作用。结果显示慢性疾病数量与死亡焦虑呈倒 U 型关系,年龄越大,老年人的死亡焦虑越低。随着年龄的增长,U 型曲线变得更加平缓,极端值向右移动。讨论:应特别关注患有慢性疾病的年轻老年人,通过提供有关慢性疾病的信息和咨询,帮助他们尽早从负面影响中恢复过来。
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引用次数: 0
Residential Relocation of Community-Dwelling Older Adults: The Role of Physical Function and the Housing Environment. 在社区居住的老年人的住宅搬迁:身体机能和居住环境的作用。
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-12-01 Epub Date: 2024-10-22 DOI: 10.1177/08982643241293585
Marielle Jensen-Battaglia, Kah Poh Loh, Ying Wang, Robert C Block, Supriya G Mohile, Emily M Agree, Christopher L Seplaki

ObjectiveMost older adults in the United States (U.S.) prefer to remain in their current housing as they age, but difficulty with mobility (e.g., walking) may make this more challenging. We estimated the association between difficulty with mobility (mobility) and residential relocation in the following year.MethodsWe included adults aged ≥65 participating in ≥2 rounds (years 2011-2019) of the National Health and Aging Trends Study. Mobility was self-reported and change in permanent address was captured by study staff. We used a prospective cohort design and logistic regression with a clustering correction to estimate adjusted associations.ResultsWe did not find evidence that mobility was associated with relocation versus no relocation in our sample of 26,444 observations from 5699 older adults. However, mobility was positively associated with moves to housing with fewer environmental barriers.DiscussionMobility is associated with relocation to housing that is more accessible and may be an indicator of greater need for supports to age in place.

目的:在美国,大多数老年人随着年龄的增长都希望留在现有的住房中,但行动不便(如步行)可能会使这一愿望变得更具挑战性。我们估算了行动不便(行动能力)与下一年住宅搬迁之间的关系:我们纳入了参与≥两轮(2011-2019 年)全国健康与老龄化趋势研究的年龄≥65 岁的成年人。流动性由研究人员自我报告,永久地址的变更由研究人员记录。我们采用了前瞻性队列设计和带有聚类校正的逻辑回归来估计调整后的关联:在来自 5699 名老年人的 26444 个观察样本中,我们没有发现流动性与搬迁或不搬迁相关的证据。然而,流动性与搬迁到环境障碍较少的住房呈正相关:讨论:流动性与搬迁到更方便的住房有关,这可能是更需要居家养老支持的一个指标。
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引用次数: 0
Combined Assessment of Cognitive and Balance Abilities to Predict Falls in Patients in the Convalescent Rehabilitation Ward. 综合评估认知能力和平衡能力以预测康复疗养病房患者的跌倒情况
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-12-01 Epub Date: 2024-11-18 DOI: 10.1177/08982643241302366
Koki Kawamura, Shota Ishino, Masato Hotta, Hitoshi Kagaya, Izumi Kondo, Kenichi Ozaki, Manabu Kokubo

ObjectiveThis study aimed to investigate the relationship between falls and cognitive and balance problems in patients.MethodsThis retrospective observational study analyzed the medical records of 1010 older patients admitted to a convalescent rehabilitation ward. The primary endpoint was fall occurrence during ward stays. The main outcomes were the Mini-Mental State Examination (MMSE) and Standing Test for Imbalance and Disequilibrium (SIDE), with patients divided into groups of MMSE ≥28 and <28 and SIDE ≥2b and <2b.ResultsDuring ward stays, 220 patients (22%) fell. Estimating the fall risk of the MMSE ≥28 + SIDE ≥2b group compared to that of other groups revealed that only the MMSE <28 + SIDE <2b group had a significantly higher fall risk, with a hazard ratio [95% confidence interval] of 3.13 [1.51-6.46].ConclusionCombined MMSE and SIDE assessment at ward admission facilitated the easy identification of individuals at high fall risk.

研究目的本研究旨在探讨跌倒与患者认知和平衡问题之间的关系:这项回顾性观察研究分析了入住疗养康复病房的 1010 名老年患者的医疗记录。研究的主要终点是住院期间的跌倒发生率。主要结果为迷你精神状态检查(MMSE)和站立失衡和不平衡测试(SIDE),将患者分为MMSE≥28组和结果组:在病房住院期间,有220名患者(22%)跌倒。在估算 MMSE≥28 + SIDE≥2b 组与其他组的跌倒风险时发现,只有 MMSE 结论:入院时进行 MMSE 和 SIDE 联合评估有助于轻松识别高跌倒风险人群。
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引用次数: 0
Gender Gap in Cancer-Free Life Expectancy in the United States: The Association With Smoking, Poor Diet, and Physical Inactivity. 美国无癌预期寿命的性别差异:与吸烟、不良饮食和缺乏运动有关。
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-11-26 DOI: 10.1177/08982643251404299
Alessandro Feraldi, Shubhankar Sharma, Cristina Giudici

BackgroundWhile life expectancy has increased globally, chronic disease burdens remain high. Cancer, despite improved survival, remains a major cause of disability and the second leading cause of death. Though behavioral risks such as smoking, poor diet, and physical inactivity are linked to cancer, few studies examine their impact on cancer-free life expectancy and gender disparities.MethodsUsing U.S. Health and Retirement Study data (2004-2020) and a multistate model approach, we estimated cancer-free life expectancy and life expectancy in individuals with cancer at age 50+, examining gender differences and their associations with smoking, poor diet, and physical inactivity.ResultsAt age 50, women live 2.7 more years cancer-free than men (27.3 vs. 24.6 years). Risky behaviors reduce cancer-free life expectancy in both sexes, but women lose more years than men.ConclusionsGender-sensitive public health strategies targeting healthy behaviors could extend cancer-free life expectancy and reduce gender gaps in aging populations.

虽然全球预期寿命有所增加,但慢性病负担仍然很高。癌症尽管提高了生存率,但仍然是造成残疾的主要原因和第二大死亡原因。虽然吸烟、不良饮食和缺乏运动等行为风险与癌症有关,但很少有研究调查它们对无癌症预期寿命和性别差异的影响。方法使用美国健康与退休研究数据(2004-2020年)和多州模型方法,我们估计了50岁以上癌症患者的无癌预期寿命和预期寿命,研究了性别差异及其与吸烟、不良饮食和缺乏运动的关系。结果50岁时,女性无癌寿命比男性多2.7年(27.3年对24.6年)。危险行为会降低男女无癌预期寿命,但女性比男性减少的寿命更长。结论以健康行为为目标的性别敏感公共卫生策略可延长老年人群的无癌预期寿命,缩小性别差距。
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引用次数: 0
Vision and Cognitive Difficulties From Midlife to Late Life: Findings From the National Health Interview Survey. 从中年到晚年的视力和认知困难:来自全国健康访谈调查的结果。
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-11-19 DOI: 10.1177/08982643251399459
Daniel Jung, Eunhae Shin

ObjectivesTo examine whether the association between vision and cognitive difficulties varies by age group.MethodsWe analyzed pooled data from the 2021-2023 National Health Interview Survey, including 52,582 U.S. adults aged 45 and older. Vision and cognitive difficulties were based on self-reports. Logistic regression with interaction terms assessed age-related differences.ResultsVision difficulty was reported by 22.7% of respondents. It was associated with over twice the odds of cognitive difficulty among adults aged 65-84 (adjusted odds ratio (aOR) = 2.2, p < 0.001), stronger in midlife (ages 45-64; interaction aOR = 1.2, p = 0.002), and weaker among those 85+ (interaction aOR = 0.7, p = <0.001). The predicted probabilities show that adults with vision difficulty were consistently more likely to report cognitive difficulty across all age groups, with the relative difference decreasing with age.DiscussionVision difficulty is linked to higher odds of cognitive difficulty, especially in midlife. Early screening and intervention may support cognitive health across the life course.

目的探讨视力与认知障碍之间的关系是否因年龄组而异。方法:我们分析了来自2021-2023年全国健康访谈调查的汇总数据,其中包括52582名45岁及以上的美国成年人。视力和认知障碍是基于自我报告。使用相互作用项的逻辑回归评估了年龄相关的差异。结果22.7%的被调查者有视力困难。在65-84岁的成年人中,它与认知困难的几率相关(校正比值比(aOR) = 2.2, p < 0.001),在中年(45-64岁;交互作用比值比(aOR) = 1.2, p = 0.002),在85岁以上的成年人中较弱(交互作用比值比= 0.7,p = 0.001)
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引用次数: 0
Association of Physical Activity in Midlife With Mobility Limitations and Falls in Old Age-A Longitudinal Twin Study. 中年体育活动与老年活动能力限制和跌倒的关系——一项纵向双胞胎研究。
IF 2.2 3区 医学 Q2 GERONTOLOGY Pub Date : 2025-11-12 DOI: 10.1177/08982643251395871
Pia Pullinen, Jari Parkkari, Jaakko Kaprio, Elina Sillanpää, Harri Sievänen, Urho Kujala, Katja Waller

ObjectiveTo study the associations between midlife physical activity and later-life mobility limitation and falls in monozygotic and dizygotic twin pairs.MethodsMidlife physical activity data from 1975, 1981, and 1990 questionnaires were drawn from the Older Finnish Twin Cohort. In the third survey, the participants were aged 46-50 years. Mobility limitations (none, some or severe) and falls (no falls, single fall or recurrent falls) were self-reported 2014-2016. Data (n = 641) were analyzed using multinomial logistic regression models.ResultsIn individual-level analysis a low level of physical activity in midlife was associated with severe mobility limitations. In within-twin pair analyses physical activity in midlife was associated with single falls among all pairs.DiscussionLower levels of self-reported physical activity during midlife were associated with severe mobility limitations over two decades later. However, this association was attenuated when controlled for genetic factors.

目的探讨同卵和异卵双胞胎中年体育活动与晚年活动能力受限和跌倒的关系。方法从老年芬兰双胞胎队列中抽取1975年、1981年和1990年的中年体育活动数据。在第三次调查中,参与者的年龄在46-50岁之间。2014-2016年自我报告活动受限(无、部分或严重)和跌倒(无跌倒、单次跌倒或复发跌倒)。数据(n = 641)采用多项逻辑回归模型进行分析。结果在个体水平分析中,中年低水平的身体活动与严重的行动能力限制有关。在对双胞胎的分析中,中年体育活动与所有双胞胎的单次跌倒有关。中年自我报告的低水平体力活动与20年后严重的行动能力限制有关。然而,当控制遗传因素时,这种关联减弱了。
{"title":"Association of Physical Activity in Midlife With Mobility Limitations and Falls in Old Age-A Longitudinal Twin Study.","authors":"Pia Pullinen, Jari Parkkari, Jaakko Kaprio, Elina Sillanpää, Harri Sievänen, Urho Kujala, Katja Waller","doi":"10.1177/08982643251395871","DOIUrl":"https://doi.org/10.1177/08982643251395871","url":null,"abstract":"<p><p>ObjectiveTo study the associations between midlife physical activity and later-life mobility limitation and falls in monozygotic and dizygotic twin pairs.MethodsMidlife physical activity data from 1975, 1981, and 1990 questionnaires were drawn from the Older Finnish Twin Cohort. In the third survey, the participants were aged 46-50 years. Mobility limitations (none, some or severe) and falls (no falls, single fall or recurrent falls) were self-reported 2014-2016. Data (<i>n</i> = 641) were analyzed using multinomial logistic regression models.ResultsIn individual-level analysis a low level of physical activity in midlife was associated with severe mobility limitations. In within-twin pair analyses physical activity in midlife was associated with single falls among all pairs.DiscussionLower levels of self-reported physical activity during midlife were associated with severe mobility limitations over two decades later. However, this association was attenuated when controlled for genetic factors.</p>","PeriodicalId":51385,"journal":{"name":"Journal of Aging and Health","volume":" ","pages":"8982643251395871"},"PeriodicalIF":2.2,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145497417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Aging and Health
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