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Points to consider for incorporating climate impacts into health economic evaluation. 将气候影响纳入卫生经济评价时应考虑的要点。
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2026-01-07 DOI: 10.1007/s10198-025-01859-3
Jule Oldenburg, Oliver Lange, Mattis Keil, Scott McAlister, Rachael Morton, Don Husereau, Wolf Rogowski

Objectives: Methodological approaches for incorporating the external effects resulting from climate impacts into health economic evaluation (HEE) are a vivid field of research. Combining established standards for reporting HEE and climate footprints (CF), our aim is to develop a structured list of points to consider for reporting full HEE that combines the two methodologies, referred to as climate-extended HEE METHODS: We mapped a transparency catalogue with methodological items for estimating CF to the reporting items described in the Consolidated Health Economic Evaluation Reporting Standards (CHEERS). We identified synergies and developed a proposal of methodological points to report for climate-extended HEE, structured by the CHEERS items. The proposal was validated using three published climate-extended HEEs and a hypothetical case study..

Results: We proposed extensions to 18 reporting items of CHEERS, for example, adding more detail to the measurement and valuation of resources and costs to facilitate a process- or cost-based estimation of CF. Using three identified publications and a hypothetical case study, examples on how all items could be addressed are provided, including a presentation of climate-extended versions of the standard summary measures of HEE.

Conclusions: The proposed catalogue can be used for reporting and reviewing climate-extended HEEs. Further work is necessary to include planetary boundaries beyond climate change. Future steps could be, first, to develop a reporting standard within a formal Delphi process of all relevant stakeholders. Second, the catalogue can be used to develop standards of analytic choices for specific decision makers or problems.

目的:将气候影响引起的外部影响纳入卫生经济评估(HEE)的方法学方法是一个生动的研究领域。结合报告HEE和气候足迹(CF)的既定标准,我们的目标是开发一个结构化的点列表,以考虑结合两种方法报告完整的HEE,称为气候扩展HEE方法:我们将估算CF的方法项目的透明度目录映射到综合卫生经济评估报告标准(CHEERS)中描述的报告项目。我们确定了协同作用,并制定了一项方法要点建议,以报告气候延长的HEE,由CHEERS项目构成。该建议通过三个已发表的气候扩展HEEs和一个假设的案例研究进行了验证。例如,我们建议扩展到CHEERS的18个报告项目,为资源和成本的测量和评估增加更多细节,以促进基于过程或成本的CF估计。使用三份确定的出版物和一个假设的案例研究,提供了如何解决所有项目的例子,包括气候扩展版本的HEE标准总结措施的介绍。结论:拟议的目录可用于报告和审查气候扩展的HEEs。有必要进一步开展工作,将气候变化以外的地球边界纳入考虑范围。未来的步骤可能是,首先,在所有相关利益相关者的正式德尔菲过程中制定一项报告标准。其次,该目录可用于制定针对特定决策者或问题的分析选择标准。
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引用次数: 0
Bridging success in the labour market: does continuity of general practitioners' care matter for individuals with common mental disorders? 在劳动力市场取得成功的桥梁:全科医生的护理连续性对普通精神障碍患者有影响吗?
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2026-01-07 DOI: 10.1007/s10198-025-01882-4
M Kamrul Islam, Håvard Thorsen Rydland, Egil Kjerstad

Mental illnesses impose substantial burdens on individuals, families, and society, encompassing both severe personal consequences and high societal costs. This study examines whether improved continuity of care with regular general practitioners (RGP-CoC) is associated with better labour market outcomes for individuals diagnosed with common mental disorders (CMDs). Using administrative registry data for 139,873 individuals with CMDs (N = 371,825 observations) from 2014/15 to 2017/18, we construct RGP-CoC indices within rolling two-year windows and track labour market outcomes over subsequent one-year periods. We employ a lagged design and high-dimensional fixed-effects models to robustly assess the association between RGP-CoC and labour market outcomes over the period 2016-2019. Our findings show that higher RGP-CoC is associated with improved labour market outcomes, with stronger and more robust effects observed for wage income than for employment probability. We also find a significant negative association between RGP-CoC and the likelihood of sickness absence. While the effects vary across education levels, no significant gender differences are observed. These findings highlight the vital role of RGP continuity of care in improving labour market participation and earnings, especially for individuals with CMDs. Enhancing continuity with a regular GP as a core quality metric in primary care can inform healthcare policy and support broader goals of economic inclusion.

精神疾病给个人、家庭和社会带来了沉重的负担,包括严重的个人后果和高昂的社会成本。本研究探讨了常规全科医生(RGP-CoC)护理的改善连续性是否与诊断为常见精神障碍(CMDs)的个体更好的劳动力市场结果相关。利用2014/15年至2017/18年期间139,873名CMDs患者的行政登记数据(N = 371,825个观察值),我们在滚动的两年窗口内构建了RGP-CoC指数,并在随后的一年期间跟踪劳动力市场结果。我们采用滞后设计和高维固定效应模型来稳健评估2016-2019年期间RGP-CoC与劳动力市场结果之间的关联。我们的研究结果表明,较高的RGP-CoC与改善的劳动力市场结果有关,对工资收入的影响比就业概率的影响更强、更稳健。我们还发现RGP-CoC与疾病缺勤的可能性之间存在显著的负相关。虽然不同教育水平的影响不同,但没有观察到明显的性别差异。这些发现突出了RGP在提高劳动力市场参与度和收入方面的重要作用,特别是对于患有慢性疾病的个人。作为初级保健的核心质量指标,加强常规全科医生的连续性可以为医疗保健政策提供信息,并支持更广泛的经济包容目标。
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引用次数: 0
Productivity costs associated with premature deaths due to acute myocardial infarction in Spain: analysis from 2013 to 2022. 西班牙与急性心肌梗死导致的过早死亡相关的生产力成本:2013年至2022年的分析
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2025-12-30 DOI: 10.1007/s10198-025-01881-5
Josep Darbà, Meritxell Ascanio, Antonio Rodríguez

Introduction: Acute myocardial infarction is one of the leading causes of death in Spain and a contributor to productivity loss. This condition represents an economic burden, involving significant indirect costs. Our objective here is to estimate premature deaths and productivity losses due to acute myocardial infarction in Spain during the period 2013-2022.

Methods: Productivity costs were estimated using a simulation model based on the human capital method. Mortality rates, average salaries, and employment rates were collected for the entire study period.

Results: After the analysis, acute myocardial infarction was identified as the leading cause of premature deaths related to cardiovascular diseases, accounting for 24% over the 10-year period. Additionally, an annual average of 26,935 YPLPLL was determined, with total productivity losses estimated at €5574.31 million, showing an upward trend over the reference period 2013-2022.

Conclusions: The study concludes by emphasizing the economic burden associated with acute myocardial infarction, which can assist decision-makers in allocating resources more efficiently.

简介:急性心肌梗死是西班牙死亡的主要原因之一,也是造成生产力损失的一个因素。这种情况是一种经济负担,涉及重大的间接费用。我们的目标是估计2013-2022年期间西班牙因急性心肌梗死导致的过早死亡和生产力损失。方法:采用基于人力资本法的仿真模型估算生产成本。收集了整个研究期间的死亡率、平均工资和就业率。结果:经过分析,急性心肌梗死被确定为心血管疾病相关过早死亡的主要原因,在10年期间占24%。此外,年平均产量为26,935 YPLPLL,总生产力损失估计为557431万欧元,在2013-2022年的参考期内呈上升趋势。结论:本研究强调急性心肌梗死相关的经济负担,有助于决策者更有效地配置资源。
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引用次数: 0
Patient and medical choice across public and private health providers: the case of birth timing manipulation in Brazil. 公营和私营卫生服务提供者的病人和医疗选择:巴西操纵生育时间的案例。
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2025-12-29 DOI: 10.1007/s10198-025-01835-x
Paula Spinola, Rudi Rocha

In this paper we assess the extent to which patient and physician preferences determine birth timing manipulation in public and private hospitals, among white and black mothers, using data from approximately 37 million births in Brazil. Our findings show that manipulation is markedly salient in the private sector and among white women. While the timing of births in the public sector is also influenced by specific incentives, their impact is less pronounced and more evenly distributed across racial groups. The analysis provides a comprehensive and integrated assessment of how treatment decisions respond to different individual incentives, for different population groups, and within distinct institutional settings, thus allowing for comparison of magnitude of estimates across health systems and populations.

在本文中,我们评估了在公立和私立医院中,在白人和黑人母亲中,患者和医生的偏好决定了分娩时间操纵的程度,使用了来自巴西约3700万新生儿的数据。我们的研究结果表明,这种操纵行为在私营部门和白人女性中尤为突出。虽然公共部门的生育时间也受到具体激励措施的影响,但其影响不那么明显,而且在各种族群体之间的分布更为均匀。该分析对治疗决策如何对不同个体激励、不同人群和不同机构环境作出反应进行了全面和综合的评估,从而能够比较卫生系统和人群之间的估计值。
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引用次数: 0
Broadening sources of finance for health promotion and disease prevention: Smart capacitating investment. 扩大促进健康和预防疾病的资金来源:明智的能力投资。
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2025-12-29 DOI: 10.1007/s10198-025-01874-4
Maureen Rutten-van Mölken, Holly Whiteley, Balázs Babarczy, Jacob Davies, Lucas Goossens, Lina Papartyte, Alison Maassen, Balázs Nagy, Stephen Wright, Rhiannon Tudor-Edwards
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引用次数: 0
Parental risk preferences and children's vaccination coverage. 父母风险偏好和儿童疫苗接种覆盖率。
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2025-12-29 DOI: 10.1007/s10198-025-01880-6
Flavia Coda Moscarola, Sarah Zaccagni

This paper examines vaccine hesitancy from a behavioral economics perspective, focusing on how parental risk preferences, altruism, and vaccine distrust affect children's vaccination rates. A model of parental investment in children's health is developed and expanded using empirical data from WHO, UNICEF, the World Bank, and the Global Preferences Survey. The study utilizes a fractional response probit model to analyze data from 69 countries, accounting for both stringent and non-stringent vaccination policies. Results show that risk aversion, altruism, and trust are positively associated with vaccination coverage, with the impact varying by policy stringency. In countries with stringent policies, risk aversion is the most significant factor, while altruism and distrust are more influential in countries with less strict policies. However, the effects of these factors are modest, with income levels accounting for most cross-country differences. The study calls for further research using more recent, individual-level data. Highlights We develop a theoretical framework suggesting that parents with higher risk aversion and altruism are more likely to invest in their children's health, particularly in vaccination decisions, extending current literature insights. Our model is empirically tested using macro-level data on parental risk preferences and altruism from the Global Preferences Survey (GPS), combined with WHO and UNICEF vaccination coverage data for ten diseases in one-year-old children. The analysis reveals a positive association between parental risk aversion, altruism, and vaccination coverage across 69 countries, moderated by the stringency of national vaccination policies. In countries with stringent vaccination policies, risk aversion predominantly drives vaccination coverage, whereas in less stringent environments, altruism and vaccine distrust play a more significant role. Vaccination coverage is notably lower in low-income countries.

本文从行为经济学的角度考察了疫苗犹豫,重点关注父母的风险偏好、利他主义和疫苗不信任如何影响儿童的疫苗接种率。利用来自世卫组织、儿童基金会、世界银行和全球偏好调查的经验数据,开发和扩大了父母对儿童健康投资的模型。该研究利用分数反应概率模型来分析来自69个国家的数据,同时考虑了严格和非严格的疫苗接种政策。结果表明,风险规避、利他主义和信任与疫苗接种覆盖率呈正相关,其影响因政策严格程度而异。在政策严格的国家,风险规避是最重要的因素,而在政策不严格的国家,利他主义和不信任的影响更大。然而,这些因素的影响是有限的,收入水平是造成跨国差异的主要原因。该研究呼吁使用更近期的个人层面数据进行进一步研究。我们发展了一个理论框架,表明具有更高风险厌恶和利他主义的父母更有可能为孩子的健康投资,特别是在疫苗接种决策方面,扩展了当前的文献见解。我们的模型使用来自全球偏好调查(GPS)的关于父母风险偏好和利他主义的宏观数据,结合世卫组织和联合国儿童基金会对一岁儿童10种疾病的疫苗接种覆盖率数据进行了实证检验。分析显示,在69个国家中,父母风险厌恶、利他主义和疫苗接种覆盖率之间存在正相关关系,并受到国家疫苗接种政策严格程度的影响。在疫苗接种政策严格的国家,风险规避主要推动了疫苗接种覆盖率,而在不那么严格的环境中,利他主义和疫苗不信任发挥了更重要的作用。低收入国家的疫苗接种覆盖率明显较低。
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引用次数: 0
Health expenditure in Africa: examining the synergistic impact of economic policy uncertainty and governance quality. 非洲卫生支出:审查经济政策不确定性和治理质量的协同影响。
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2025-12-29 DOI: 10.1007/s10198-025-01879-z
Ekene ThankGod Emeka, Simplice Asongu

This study examines the relevance of governance quality in shaping the effect of economic policy uncertainty on several health expenditure indicators, including external health expenditure, national health expenditure, public health expenditure, and private health expenditure. The analysis is based on a sample of fifty-three African countries spanning 2005 to 2022. The adopted empirical strategy comprises the interactive dynamic two-step System Generalized Method of Moments (SGMM). The analysis is structured such that various governance dimensions-economic, political, and institutional governance moderate economic policy uncertainty to reduce health expenditure. Overall, governance dynamics do not effectively moderate economic policy uncertainty to negatively influence health expenditure dynamics. Specifically, a corresponding aggregated governance threshold of 2.2264, is needed to completely mitigate the positive effect of economic policy uncertainty on external health expenditure. Furthermore, improved infrastructure, employment, and foreign direct investment are potent channels for reducing some health expenditure dynamics within the continent. The associated policy implications of this study are discussed within the framework of the African Union's Agenda 2063 and the United Nations Sustainable Development Goals (SDGs).

本研究考察了治理质量在影响经济政策不确定性对若干卫生支出指标的影响方面的相关性,这些指标包括外部卫生支出、国家卫生支出、公共卫生支出和私人卫生支出。该分析基于2005年至2022年间53个非洲国家的样本。采用的经验策略包括交互动态两步系统广义矩量法(SGMM)。分析的结构是这样的,各种治理维度——经济、政治和制度治理——缓和经济政策的不确定性,以减少卫生支出。总体而言,治理动态并不能有效地缓和经济政策的不确定性,从而对卫生支出动态产生负面影响。具体而言,需要相应的综合治理阈值为2.2264,才能完全减轻经济政策不确定性对外部卫生支出的积极影响。此外,改善基础设施、就业和外国直接投资是减少非洲大陆某些卫生支出动态的有力渠道。本研究的相关政策影响将在非洲联盟《2063年议程》和联合国可持续发展目标(sdg)的框架内进行讨论。
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引用次数: 0
Assessing the economic burden of complicated urinary tract infection: A systematic literature review. 评估复杂性尿路感染的经济负担:系统的文献综述。
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2025-12-29 DOI: 10.1007/s10198-025-01846-8
Edward Broughton, Ann Colosia, Meryem Bektas, Kristi Kuper, Ramy Kotb

Background: Complicated urinary tract infections (cUTIs) arise in patients with structural or functional abnormalities of the genitourinary tract or those with nonurogenital comorbidities. cUTIs can be associated with high healthcare resource utilization (HCRU). We conducted a systematic literature review (SLR) to understand the economic burden of cUTI in a selection of countries likely to have early adoption of innovative antibiotic combination regimens.

Methods: The SLR was conducted to identify observational studies evaluating the burden of cUTI in France, Italy, Germany, Spain, the United Kingdom, China, Japan, and the United States (US) for 2013-2023 (PROSPERO-CRD42023454794) using PubMed, Embase, Cochrane, and EconLit databases, with no language limitations.

Results: Of 1,041 studies identified, 154 from databases were selected for full-text review; of these, 53 met the economic inclusion criteria, reporting direct costs and/or healthcare utilization. Mean hospitalization costs per cUTI varied from $2,747 in China to $32,790 for catheter-associated UTI (CAUTI) acquired in the hospital among US children. Length of stay (LOS) was the most common HCRU outcome reported. Across 3 multicountry studies, LOS for cUTI hospitalization was similar, with a median length of 7 days. Patients with CAUTI had longer LOS than did controls.

Conclusions: Available evidence from the US studies indicates that economic burden associated with cUTI is substantial. However, except for the US, direct costs were missing or reported in only 1 or 2 studies for each of the other countries examined. Similarly, HCRU outcomes were missing or reported in only a few studies, except for the US and Spain.

背景:复杂性尿路感染(cUTIs)发生在泌尿生殖道结构或功能异常或非泌尿生殖道合并症的患者中。cui可能与高医疗保健资源利用率(HCRU)相关联。我们进行了系统的文献综述(SLR),以了解在一些可能早期采用创新抗生素联合治疗方案的国家中cUTI的经济负担。方法:采用无语言限制的PubMed、Embase、Cochrane和EconLit数据库,对2013-2023年法国、意大利、德国、西班牙、英国、中国、日本和美国(US)评估cUTI负担的观察性研究(PROSPERO-CRD42023454794)进行SLR筛选。结果:在确定的1041项研究中,从数据库中选择了154项进行全文综述;其中,53个符合经济包容性标准,报告了直接成本和/或医疗保健利用情况。每次UTI的平均住院费用从中国的2,747美元到美国儿童在医院获得的导管相关UTI (CAUTI)的32,790美元不等。住院时间(LOS)是最常见的HCRU结果。在3项多国研究中,cUTI住院的LOS相似,中位长度为7天。CAUTI患者的LOS比对照组长。结论:来自美国研究的现有证据表明,与cUTI相关的经济负担是巨大的。然而,除美国外,在其他国家的研究中,只有1到2项研究没有直接成本或报告了直接成本。同样,除了美国和西班牙外,只有少数研究缺少或报告了HCRU结果。
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引用次数: 0
How tax structures for retail cannabis shape cannabis use among youth and young adults: evidence from a volumetric choice experiment. 零售大麻的税收结构如何影响青年和年轻人的大麻使用:来自容量选择实验的证据。
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2025-12-29 DOI: 10.1007/s10198-025-01875-3
Lei Xu, Yanyun He, Hojin Park, Shiqi Zhang, Shaoying Ma, Ce Shang
<p><strong>Background: </strong>Despite ongoing debates about cannabis regulation, little is known about how tax policy design influences cannabis use among U.S. adolescents and young adults (AYAs). With states adopting diverse taxation schemes based on weight, price, or product potency, evaluating how these approaches affect consumption is critical for evidence-based policymaking.</p><p><strong>Aim: </strong>This study uses a split sample volumetric choice experiment (VCE) to examine how variations in pretax prices, tax bases, tax rates, and THC levels influence both the amount of cannabis consumed and the overall intake of THC among US AYAs aged 15-20. We also estimate the own-price elasticities for four cannabis forms (legal flower, illegal flower, edibles, and cartridges) and cross-price elasticities between these products.</p><p><strong>Methods: </strong>We use a nationally representative sample of 1,100 AYA who reported current use or susceptibility to use and completed a set of hypothetical purchase tasks featuring choices among four product forms (legal flower, illegal flower, edibles, cartridges). Respondents were randomized to three tax bases: weight-, price-, or potency-based taxation, where pre-tax price levels, tax rates, and THC levels additionally vary. We estimated own- and cross-price elasticities and assessed how AYA current and susceptible users adjusted cannabis consumption in response to the varying attributes using zero-inflated negative binomial and fixed effects models.</p><p><strong>Results: </strong>Higher pre-tax prices and elevated tax rates significantly reduce both purchase quantities and total THC intake among current and susceptible AYA users. Products with higher THC levels increased THC intake but did not affect quantity consumption, suggesting that these users continue to purchase similar quantities but opt for more potent products. Compared to weight-based taxation, potency-based taxes (i.e., THC) were associated with a 30%-32% increase in cannabis quantity consumption. The price elasticities of cannabis demand were -0.3, with edibles being complements to other forms and illegal flowers being substitutes for legal flowers and cartridges. Compared to weight-based taxes, THC-based taxes significantly reduce the impact of THCs in increasing THC consumption. Finally, the impact of taxes on reducing THC consumption from legal products may be completely offset by shifting from legal to illegal products.</p><p><strong>Conclusions: </strong>For AYAs who are using or susceptible to using cannabis, tax increases can effectively reduce the quantity and THC consumption, albeit a tax rate beyond 60% of pretax prices or equivalent generating no additional reductions. Compared to weight-based taxes, potency-based and price-based taxes reduce the consumption of high THC products, but potency-based taxes may also increase the consumption of low THC products. Given that higher prices on cartridges and edibles do not drive AYAs'
背景:尽管关于大麻监管的争论正在进行,但人们对税收政策设计如何影响美国青少年和年轻人(AYAs)的大麻使用知之甚少。随着各州根据重量、价格或产品效力采取不同的税收方案,评估这些方法如何影响消费对于基于证据的政策制定至关重要。目的:本研究使用分割样本容量选择实验(VCE)来研究税前价格、税基、税率和四氢大麻酚水平的变化如何影响15-20岁美国青少年吸食大麻的数量和四氢大麻酚的总摄入量。我们还估计了四种大麻形式(合法花、非法花、可食用和药筒)的自身价格弹性以及这些产品之间的交叉价格弹性。方法:我们使用了具有全国代表性的1100名AYA样本,他们报告了目前的使用情况或使用敏感性,并完成了一组假设的购买任务,其中包括四种产品形式(合法花,非法花,可食用花,盒装)的选择。受访者被随机分配到三种税基:基于权重、价格或潜力的税收,其中税前价格水平、税率和四氢大麻酚水平也各不相同。我们估计了自身和交叉价格弹性,并评估了AYA当前和易感用户如何使用零膨胀负二项和固定效应模型根据不同属性调整大麻消费。结果:较高的税前价格和较高的税率显著降低了当前和易感AYA用户的购买数量和总THC摄入量。四氢大麻酚含量较高的产品增加了四氢大麻酚的摄入量,但不影响消费量,这表明这些用户继续购买类似数量的产品,但选择更强效的产品。与以重量为基础的税收相比,以效力为基础的税收(即四氢大麻酚)与大麻消费量增加30%-32%有关。大麻需求的价格弹性为-0.3,食用大麻是对其他形式的补充,非法花卉是合法花卉和药筒的替代品。与基于重量的税收相比,基于四氢大麻酚的税收显著降低了四氢大麻酚对增加四氢大麻酚消费的影响。最后,税收对减少合法产品的四氢大麻酚消费的影响可以通过从合法产品转向非法产品来完全抵消。结论:对于正在使用或可能使用大麻的未成年人来说,增加税收可以有效减少大麻的数量和四氢大麻酚的消费量,尽管税率超过税前价格的60%或等价物不会产生额外的减少。与基于重量的税收相比,基于潜力的税收和基于价格的税收减少了高THC产品的消费,但基于潜力的税收也可能增加低THC产品的消费。鉴于药盒和可食性大麻的较高价格并不会促使AYAs使用鲜花进行替代,在平衡针对四氢大麻酚的需求同时减轻管理效价税的负担方面,分级税收结构可能比效价税或基于体重的税更有优势。最后,鉴于非法花卉是合法花卉和花筒的替代品,政策影响被非法产品的可获得性所抵消。
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引用次数: 0
Cost-of-illness of myelodysplastic syndromes in Italy. A reply to Tse et al. 意大利骨髓增生异常综合征的疾病成本。对谢天赐等人的回复。
IF 3 3区 医学 Q1 ECONOMICS Pub Date : 2025-12-29 DOI: 10.1007/s10198-025-01876-2
Carlo Lazzaro
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引用次数: 0
期刊
European Journal of Health Economics
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