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Adoption Service in India: Current Scenario. 印度的收养服务:现状。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-12-01 Epub Date: 2025-12-19 DOI: 10.1007/s13224-025-02321-3
Sunita Tandulwadkar, B Kalpana, Deepti Gupta, Aishwina Anand

Adoption refers to legally taking a child to be taken care of as your own. Adoption and maintenance act guides the process of adoption in our country. CARA is one such body which streamlines the adoption process. Gynaecologists play a crucial role in guiding the couples with infertility visiting the outpatinet department for adoption after ruling out their eligibility.

收养指的是合法地把一个孩子当作自己的孩子来照顾。收养抚养法指导着我国的收养程序。CARA就是这样一个简化收养程序的机构。在排除不孕不育夫妇的收养资格后,妇科医生在指导他们到门诊部进行收养方面起着至关重要的作用。
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引用次数: 0
Risk Scoring in Pregnancy and Maternal and Perinatal Outcomes: A Prospective Observational Study from a Tertiary Care Institute in South India. 妊娠和孕产妇及围产期结局的风险评分:一项来自南印度三级保健研究所的前瞻性观察研究。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-12-01 Epub Date: 2025-08-07 DOI: 10.1007/s13224-025-02196-4
H N Darshan, Vijayan Sharmila, Priyanka Yoga, Thirunavukkarasu Arun Babu

Introduction: High-risk pregnancies refer to conditions that pose significant health risks to the mother, the foetus, or both. These pregnancies are linked to a higher incidence of maternal complications, such as antepartum haemorrhage, postpartum haemorrhage, infections, and an increased need for operative deliveries. Additionally, infants born to high-risk mothers have an increased likelihood of low birth weight, preterm birth, respiratory distress, and a higher risk of neonatal mortality.

Materials and methods: This hospital-based prospective observational study was conducted in the Department of Obstetrics and Gynecology at AIIMS Mangalagiri, a tertiary carte institute in South India over a period of two years from January 2023 to January 2025 after obtaining IEC approval. A total of 432 pregnant women were enrolled in study. Each participant was stratified into low, moderate, or high-risk categories using a risk scoring system. The maternal and foetal outcomes of each group were analysed.

Results: Among the 432 participants, 97 (22.5%) were classified as high-risk. Higher Coopland's scores were significantly associated with unfavourable maternal outcomes, including increased hospitalizations, labour inductions, operative deliveries, and intrapartum complications such as prolonged or difficult labour. The high-risk group also experienced a significantly higher incidence of postpartum haemorrhage, puerperal fever, and extended hospital stays. Additionally, adverse foetal outcomes, including preterm birth, low birth weight, low APGAR scores, the need for neonatal resuscitation, NICU admission, and prolonged NICU stays, were significantly more frequent in this group.

Conclusion: The high-risk group constituted 97 (22.5%) of pregnant women delivering at our institute, as determined by the risk scoring system. Higher risk scores were significantly associated with adverse maternal and perinatal outcomes, including complications during labour, postpartum, and neonatal care. The early detection of high-risk pregnancies using reliable risk assessment tools enables timely interventions and specialized care, ultimately enhancing the health and well-being of both mother and baby. This study highlights the significance of integrating risk evaluation methods into routine prenatal care to achieve better pregnancy outcomes.

高危妊娠是指对母亲、胎儿或两者构成重大健康风险的情况。这些妊娠与产妇并发症发生率较高有关,如产前出血、产后出血、感染以及对手术分娩的需求增加。此外,高危母亲所生的婴儿更有可能出现低出生体重、早产、呼吸窘迫和更高的新生儿死亡风险。材料和方法:这项以医院为基础的前瞻性观察性研究在获得IEC批准后,于2023年1月至2025年1月在印度南部三级医院AIIMS Mangalagiri的妇产科进行,为期两年。共有432名孕妇参加了这项研究。使用风险评分系统将每个参与者分为低、中、高风险三类。分析各组的母胎结局。结果:432名参与者中,97人(22.5%)属于高危人群。较高的copland评分与不利的产妇结局显著相关,包括住院次数增加、引产、手术分娩和分娩时并发症(如分娩时间延长或难产)。高危组产后出血、产褥热和延长住院时间的发生率也明显较高。此外,不良胎儿结局,包括早产、低出生体重、低APGAR评分、需要新生儿复苏、新生儿重症监护病房入院和延长新生儿重症监护病房住院时间,在该组中明显更频繁。结论:高危组97例(22.5%)为高危组,由风险评分系统确定。较高的风险评分与孕产妇和围产期不良结局显著相关,包括分娩、产后和新生儿护理期间的并发症。使用可靠的风险评估工具及早发现高危妊娠,能够及时采取干预措施和提供专门护理,最终增进母亲和婴儿的健康和福祉。本研究强调了将风险评估方法纳入常规产前护理以获得更好的妊娠结局的重要性。
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引用次数: 0
"Rare but Not Forgotten Five Cases of Swyer Syndrome": Case Series and Literature Review. 罕见但不被遗忘的5例斯威氏综合征:病例系列及文献回顾。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-12-01 Epub Date: 2025-08-21 DOI: 10.1007/s13224-025-02183-9
Pushplata Kumari, Minakshi Kumari, Madhurima Barik, Lilly Varghese

Introduction: Swyer syndrome is a rare condition of complete gonadal dysgenesis due to mutations in the Y chromosome SRY gene, leading to testicular underdevelopment. In this condition individuals present with a female phenotype despite having a male karyotype (46, XY).

Method and materials: This retrospective review of five cases of Swyer Syndrome at our centre since 2013.

Results: All five patients, raised as girls, presented at 18-31 years with primary amenorrhea; one had hyposmia. Breast development ranged from Tanner stage 1-4 with varying axillary hair. Internal exams showed an infantile uterus and cervix. Imaging revealed small to normal uterus and streak gonads. Elevated serum FSH and low testosterone confirmed the diagnosis (46, XY karyotype). Three patients underwent laparoscopic gonadectomy due to gonadoblastona risk; two were lost to follow-up. All received Estrogens and Progesterone replacement therapy development of secondary sexual characters.

Conclusions: Swyer syndrome requires high clinical suspicion for diagnosis. Early identification allows timely hormone therapy and consideration of gonadectomy to prevent gonadoblastona.

简介:Swyer综合征是一种罕见的由Y染色体SRY基因突变引起的完全性腺发育不良,导致睾丸发育不全的疾病。在这种情况下,个体表现为女性表型,尽管具有男性核型(46,XY)。方法与材料:回顾性分析本中心2013年以来收治的5例Swyer综合征病例。结果:5例女性患者均为18-31岁原发性闭经;一个是低体温。乳房发育从坦纳期到1-4期腋毛各异。内部检查显示婴儿子宫和子宫颈。影像显示小至正常子宫和条纹性腺。血清FSH升高和睾酮降低证实了诊断(46,XY核型)。3例患者因存在成性腺风险而行腹腔镜性腺切除术;2例未随访。所有患者均接受雌激素和黄体酮替代治疗,发展第二性征。结论:Swyer综合征的诊断需要高度的临床怀疑。早期发现可以及时进行激素治疗,并考虑进行性腺切除术以预防性腺母细胞瘤。
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引用次数: 0
The Acceptance and Refusal of Postpartum Intrauterine Devices at a Tertiary Care Center in West Bengal: A Cross-Sectional Study. 西孟加拉邦三级保健中心产后接受和拒绝宫内节育器:一项横断面研究。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-12-01 Epub Date: 2025-08-25 DOI: 10.1007/s13224-025-02215-4
Madhuparna Nandi, Partha Pratim Sharma, Atish Haldar

Background: The WHO classification of contraceptive effectiveness placed IUCD in the most effective first tier. The family welfare program, in India, has recently emphasized postpartum IUCD insertion to space childbirth, resulting in reducing childbirth-related complications and a small family norm. However, evidence suggests that the acceptability of PPIUCD is still a challenge in developing countries, though in fully informed woman, PPIUCD is a satisfactory method of contraception. Therefore, the present study will try to find out the factors associated with the acceptance and refusal of PPIUCD which is available free of cost, under the National Family Planning Program in India.

Methods: This is a cross-sectional study conducted in the Gynecology and Obstetrics Department, over a period of 1 year, from February 2023 to January 2024. Women who delivered, either vaginally or by cesarean section were included in the present study. The categorical variables were expressed as frequencies and percentages. A P value of 0.05 was considered significant.

Results: Out of 1127 women who delivered and were counseled for PPIUCD as contraception, 32.7% (368) accepted and 67.3% (759) refused it. Of all, 42.5% were from the 20-30 years age group, but acceptance of PPIUCD was seen higher (36.2%) in the 30-40 years age group. The odds of acceptance of PPIUCD were 4.2 times higher in housewives compared to working women [OR = 4.2; 95% CI: 3.2-5.6]. Women with ≥ 4 ANC checkups in recent pregnancy accepted PPIUCD use by 47.2%. 53.2% of women (404/759) cited unawareness of the method as the main cause of refusal.

Conclusion: More antenatal checkups resulted in higher acceptance of PPIUCD. Preference for another method of contraception and not being aware of PPIUCD are the major contributing factors to its refusal.

背景:世界卫生组织对避孕效果的分类将宫内节育器列为最有效的第一级。印度的家庭福利项目最近强调在产后插入宫内节育器以间隔分娩,从而减少了与分娩有关的并发症,并形成了一个小家庭规范。然而,有证据表明,PPIUCD的可接受性在发展中国家仍然是一个挑战,尽管在充分知情的妇女中,PPIUCD是一种令人满意的避孕方法。因此,本研究将试图找出与接受和拒绝在印度国家计划生育方案下免费提供的PPIUCD有关的因素。方法:这是一项横断面研究,在妇产科进行,为期1年,从2023年2月到2024年1月。分娩的妇女,无论是阴道分娩还是剖宫产,都包括在本研究中。分类变量用频率和百分比表示。P值为0.05被认为是显著的。结果:在1127名分娩妇女中,接受PPIUCD避孕的368人占32.7%,759人占67.3%。其中,20-30岁年龄组占42.5%,但30-40岁年龄组接受PPIUCD的比例较高(36.2%)。家庭主妇接受PPIUCD的几率是职业妇女的4.2倍[OR = 4.2;95% ci: 3.2-5.6]。近期妊娠ANC检查≥4次的妇女接受PPIUCD的比例为47.2%。53.2%的女性(404/759)认为不了解避孕方法是拒绝的主要原因。结论:产前检查越多,对PPIUCD的接受程度越高。对其他避孕方法的偏好和不了解PPIUCD是其拒绝的主要原因。
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引用次数: 0
Creating a Safer Tomorrow: Addressing Workplace Violence Against Women in Healthcare Settings. 创造更安全的明天:解决医疗机构中针对妇女的工作场所暴力问题。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-12-01 Epub Date: 2025-06-27 DOI: 10.1007/s13224-025-02154-0
Juhi Deshpande

Background: Workplace violence against women in healthcare is a pervasive and alarming issue with far-reaching consequences for individuals, institutions, and society.

Objective: This article aims to highlight the need for a comprehensive approach to address workplace violence, ensuring safer workplaces and promoting women's well-being.

Methods: A multi-faceted strategy is proposed, encompassing enhanced legislation, institutional accountability, gender-sensitive workplaces, education, and community outreach to dismantle the culture of silence.

Conclusion: By adopting a comprehensive approach, we can dismantle the culture of silence, promote a culture of respect and accountability, and create safer workplaces, ultimately upholding the fundamental right to safety and well-being for women in healthcare.

背景:医疗保健领域对妇女的工作场所暴力是一个普遍存在的令人担忧的问题,对个人、机构和社会产生深远影响。目的:本文旨在强调需要采取综合办法来解决工作场所暴力问题,确保工作场所更安全,促进妇女的福祉。方法:提出了一项多方面的战略,包括加强立法、机构问责、性别敏感的工作场所、教育和社区外拓展,以消除沉默文化。结论:通过采取综合办法,我们可以消除沉默文化,促进尊重和问责文化,创造更安全的工作场所,最终维护妇女在医疗保健领域享有安全和福祉的基本权利。
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引用次数: 0
Revisiting "3 Delays Model" for Critical Analysis of Hypertensive Maternal Mortality in a Tertiary Care Centre. 重新审视“3延迟模型”对高血压产妇死亡率的关键分析在三级保健中心。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-01 Epub Date: 2025-07-18 DOI: 10.1007/s13224-025-02158-w
Neha Chaudhary, Seema Mehrotra, Vandana Solanki, Urmila Singh

Background: Hypertensive disorders in pregnancy are responsible for 14% of maternal deaths. Maternal mortality is not only due to medical disorder but also due to underlying social-cultural factors lead to delays in getting timely and appropriate intervention. This study aimed to analyse three delays, to identify socio-cultural, demographic and accessibility factors that contributed to maternal deaths due to hypertension in pregnancy.

Method: It was a prospective observational study. Verbal autopsy was done for each maternal death that occurred due to hypertensive disorder. The "3 delay model" concept was used in collection and analysis of data for each maternal death. The Chi-square test (χ 2) and multivariable logistic regression model were used to accomplish the study objectives.

Results: Out of 326 maternal deaths, 52 deaths were due to hypertensive disorders. Pulmonary oedema, eclamptic encephalopathy, sepsis and cerebrovascular accident were the major causes of maternal mortality. In thirty-nine (75%) type I delay was the most significant contributor of maternal death. Twenty-four (46.15%) and 14 (26.9%) had Type II/III delay. The reasons for level I delay were failure to recognize the danger signs, delay in decision-making, no ANC registration, Type II delay being lack of timely transport facility, type III delay being lack of adequate monitoring, delay in initiating treatment and substandard care in hospital were observed.

Conclusions: Socio-cultural and demographic factors significantly contribute to the direct or indirect medical cause of maternal death. Analysing these factors provide deep insight into the maternal death and will provide useful information for guiding the policy makers to take corrective actions and direct their programmes and policies such as strengthening referral networking, widespread coverage of healthcare facility and raising awareness of danger signs of pregnancy by reaching at grass root levels.

背景:妊娠期高血压疾病占孕产妇死亡的14%。产妇死亡不仅是由于医疗紊乱,而且还由于潜在的社会文化因素导致无法及时和适当地进行干预。这项研究的目的是分析三种延误,以确定导致孕妇因妊娠期高血压死亡的社会文化、人口和无障碍因素。方法:采用前瞻性观察研究。对每一例因高血压疾病死亡的产妇进行了死因推断。“3延迟模型”的概念被用于收集和分析每一个产妇死亡的数据。采用卡方检验(χ 2)和多变量logistic回归模型完成研究目标。结果:326例产妇死亡中,52例死于高血压疾病。肺水肿、子痫性脑病、败血症和脑血管意外是产妇死亡的主要原因。在39个(75%)国家中,I型延迟是孕产妇死亡的最主要原因。24例(46.15%)和14例(26.9%)为II/III型延迟。第一级延误的原因是未能识别危险迹象、决策延误、未进行ANC登记;第二类延误是缺乏及时的运输设施;第三类延误是缺乏充分的监测、延迟开始治疗和医院护理不合格。结论:社会文化和人口因素是造成产妇死亡的直接或间接医疗原因的重要因素。分析这些因素有助于深入了解产妇死亡情况,并将为指导决策者采取纠正行动和指导其方案和政策提供有用的信息,例如加强转诊网络、广泛覆盖保健设施以及通过深入基层提高对怀孕危险迹象的认识。
{"title":"Revisiting \"3 Delays Model\" for Critical Analysis of Hypertensive Maternal Mortality in a Tertiary Care Centre.","authors":"Neha Chaudhary, Seema Mehrotra, Vandana Solanki, Urmila Singh","doi":"10.1007/s13224-025-02158-w","DOIUrl":"https://doi.org/10.1007/s13224-025-02158-w","url":null,"abstract":"<p><strong>Background: </strong>Hypertensive disorders in pregnancy are responsible for 14% of maternal deaths. Maternal mortality is not only due to medical disorder but also due to underlying social-cultural factors lead to delays in getting timely and appropriate intervention. This study aimed to analyse three delays, to identify socio-cultural, demographic and accessibility factors that contributed to maternal deaths due to hypertension in pregnancy.</p><p><strong>Method: </strong>It was a prospective observational study. Verbal autopsy was done for each maternal death that occurred due to hypertensive disorder. The \"3 delay model\" concept was used in collection and analysis of data for each maternal death. The Chi-square test (<i>χ</i> <sup>2</sup>) and multivariable logistic regression model were used to accomplish the study objectives.</p><p><strong>Results: </strong>Out of 326 maternal deaths, 52 deaths were due to hypertensive disorders. Pulmonary oedema, eclamptic encephalopathy, sepsis and cerebrovascular accident were the major causes of maternal mortality. In thirty-nine (75%) type I delay was the most significant contributor of maternal death. Twenty-four (46.15%) and 14 (26.9%) had Type II/III delay. The reasons for level I delay were failure to recognize the danger signs, delay in decision-making, no ANC registration, Type II delay being lack of timely transport facility, type III delay being lack of adequate monitoring, delay in initiating treatment and substandard care in hospital were observed.</p><p><strong>Conclusions: </strong>Socio-cultural and demographic factors significantly contribute to the direct or indirect medical cause of maternal death. Analysing these factors provide deep insight into the maternal death and will provide useful information for guiding the policy makers to take corrective actions and direct their programmes and policies such as strengthening referral networking, widespread coverage of healthcare facility and raising awareness of danger signs of pregnancy by reaching at grass root levels.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 5","pages":"415-421"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12579072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-Invasive Estimation of Haemoglobin in Pregnancy: Assessing Accuracy and the Effect of Skin Pigmentation. 妊娠期血红蛋白的无创评估:评估准确性和皮肤色素沉着的影响。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-01 Epub Date: 2025-07-08 DOI: 10.1007/s13224-025-02192-8
Nishita Mehta, Amarnath Bhide, Basia Chmielewska, Julia Zollner

Objective: To investigate the accuracy of a non-invasive device to measure haemoglobin and compare it with the laboratory gold standard in pregnant women, and to assess if the results vary by skin pigmentation.

Material and methods: Women attending pre-operative assessment before a scheduled caesarean section were invited, and informed consent was taken. Haemoglobin (Hb) estimation was performed using a non-invasive point-of-care device (Masimo Pronto pulse co-oximeter). Venous blood sample was collected for full blood count. The skin pigmentation was classified using the Fitzpatrick scale. Bias and 95% limits of agreement were examined for haemoglobin estimation. Accuracy of the pulse co-oximeter device was assessed in the six Fitzpatrick scales of skin tone.

Results: A total of 122 women were recruited. Twelve of these women (9.8%) had their haemoglobin values < 105 g/L. The Pronto device showed a significant positive bias. The mean difference was 23.4 (SD: 11.97) g/L. The 95% limits of agreement were - 0.06 to 46.9 g/L. The difference between the two methods was unrelated to the skin pigmentation. The area under the ROC curve was 0.705 (95% CI: 0.817-0.593, p = 0.013) for the detection of anaemia.

Conclusions: The point-of-care device (Masimo Pronto pulse co-oximeter) overestimates the Hb readings in pregnant women, and a correction is needed to estimate the real Hb value. The accuracy is unaffected by skin pigmentation. The device may be a potentially useful screening tool in the detection of anaemia in pregnancy in limited resource setting, but the 95% limits of agreements are relatively wide.

目的:探讨一种无创装置测量孕妇血红蛋白的准确性,并将其与实验室金标准进行比较,并评估结果是否因皮肤色素沉着而异。材料和方法:邀请预定剖宫产前参加术前评估的妇女,并取得知情同意。血红蛋白(Hb)的估计使用无创点护理设备(Masimo Pronto脉搏共氧仪)。采集静脉血进行全血细胞计数。采用Fitzpatrick评分法对皮肤色素沉着进行分类。检查血红蛋白估计的偏倚和95%的一致限度。脉搏共血氧计装置的准确性在肤色的六个菲茨帕特里克量表进行评估。结果:共招募122名女性。其中12名妇女(9.8%)的血红蛋白值p = 0.013)用于检测贫血。结论:护理点设备(Masimo Pronto脉搏共血氧仪)高估了孕妇的Hb读数,需要进行校正以估计真实的Hb值。准确性不受皮肤色素沉着的影响。在资源有限的情况下,该设备可能是检测妊娠贫血的潜在有用筛查工具,但95%的协议限制相对较宽。
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引用次数: 0
Social Media in Obstetrics & Gynaecology: How Far can we Go?? 社交媒体在妇产科:我们能走多远?
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-01 Epub Date: 2025-10-16 DOI: 10.1007/s13224-025-02253-y
Sujata Dalvi

In the last decade, social media has evolved from a casual communication tool to a powerful platform for professional engagement, education, and advocacy -particularly in the field of Obstetrics and Gynaecology (Ob Gyn). As maternal health, reproductive rights, and gynaecologic care continue to occupy central roles in public discourse, social media offers Ob Gyn professionals a unique opportunity to amplify evidence-based information, foster community, and shape the future of women's health. Ob Gyn professionals have increasingly embraced platforms like Twitter, LinkedIn, Instagram, and YouTube to share research findings, clinical insights, and public health messages. This shift is not merely cosmetic, but it reflects a deeper transformation in how knowledge is disseminated and consumed. Despite its promise, social media in Ob Gyn is not without pitfalls. This article explores the multifaceted impact of social media in Ob Gyn, from academic visibility and patient education to ethical considerations and institutional strategy.

在过去的十年中,社交媒体已经从一个随意的交流工具发展成为一个强大的专业参与、教育和宣传平台——特别是在妇产科领域。随着孕产妇健康、生殖权利和妇科护理继续在公共话语中占据核心地位,社交媒体为妇产科专业人员提供了一个独特的机会,可以扩大循证信息、促进社区发展和塑造妇女健康的未来。妇产科专业人士越来越多地使用Twitter、LinkedIn、Instagram和YouTube等平台来分享研究成果、临床见解和公共卫生信息。这种转变不仅仅是表面上的,它反映了知识传播和消费方式的更深层次的转变。尽管前景光明,但社交媒体在妇产科领域并非没有陷阱。本文探讨了社交媒体对妇产科的多方面影响,从学术知名度和患者教育到伦理考虑和机构战略。
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引用次数: 0
Extended Letrozole Treatment for Ovulation Induction and Clinical Pregnancy in Conventional Treatment-resistant Polycystic Ovary Syndrome Patients: A Prospective Parallel Randomized Clinical Trial. 延长来曲唑治疗常规治疗抵抗性多囊卵巢综合征患者的促排卵和临床妊娠:一项前瞻性平行随机临床试验。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-01 Epub Date: 2025-07-18 DOI: 10.1007/s13224-025-02163-z
Ferdous Mehrabian, Nastaran Zamani Dehkordi, Faezeh Zakerinasab, Fatemeh Zarimeidani, Rahem Rahmati, Masoud Lotfizadeh, Hosein Ataei-Goujani, Elham Naghshineh, Hatav Ghasemi Tehrani

Background/purpose: Polycystic ovarian syndrome (PCOS) is the most frequent cause of anovulatory infertility. Due to the high rates of ovulation and pregnancies, Letrozole (LE) has recently been considered the first-line ovulation induction medication administered to PCOS patients. Nowadays, different clinical trials have examined various LE protocol methods to reach the best strategy for infertility therapy in PCOS patients.

Methods: This study was designed as a single-center, parallel randomized [1:1] clinical trial. It was registered on the World Health Organization trial registry of IRAN with registration number IRCT20110908007513N19. Eligible participants with PCOS resistant to conventional treatment were assigned to receive extended LE treatment for 7 days (group A) and 10 days (group B). Primary endpoints included ovulation rate and follicle measurements, while secondary endpoints assessed pregnancy rates and complications. A per-protocol analysis was considered.

Results: Among 55 participants, the mean age was 29.27, with a BMI of 25.51. In group A, 27/27 patients were ovulated, and lastly, 10 indicated clinical pregnancy. In group B, 27/28 patients were ovulated, and only 5 indicated clinical pregnancy. While the variation in clinical pregnancy rates between the groups in our study did not achieve statistical significance, the observed trend indicates a potentially significant clinical implication. Hormone profiles, follicle sizes, and endometrial thickness did not significantly differ between clinically pregnant and non-pregnant females in both groups. No complications were observed.

Conclusion: Although several conventional treatment-resistant females eventually became pregnant in a 7- or 10-day course of treatment, there are no notable differences between LE therapy in 7-day and 10-day groups. Further extensive studies are needed to validate the findings. Healthcare professionals should take this trend into account when assessing treatment alternatives, particularly within the framework of personalized patient care, as even slight enhancements in pregnancy rates can have significant effects.

World health organization trial registry of iran registration number: IRCT20110908007513N19.

背景/目的:多囊卵巢综合征(PCOS)是无排卵性不孕最常见的原因。由于排卵率和妊娠率高,来曲唑(LE)最近被认为是PCOS患者的一线促排卵药物。目前,不同的临床试验已经研究了各种LE方案方法,以达到PCOS患者不孕治疗的最佳策略。方法:本研究采用单中心、平行随机[1:1]临床试验。已在伊朗世界卫生组织试验注册中心注册,注册号为IRCT20110908007513N19。对常规治疗有抵抗力的PCOS患者被分配接受延长LE治疗7天(A组)和10天(B组)。主要终点包括排卵率和卵泡测量,而次要终点评估妊娠率和并发症。考虑了每个协议的分析。结果:55名参与者平均年龄为29.27岁,BMI为25.51。A组27例患者中有27例排卵,10例临床妊娠。B组28例患者中有27例排卵,仅有5例临床妊娠。虽然我们研究中各组临床妊娠率的差异没有统计学意义,但观察到的趋势表明了潜在的重要临床意义。两组临床怀孕和非怀孕女性的激素谱、卵泡大小和子宫内膜厚度没有显著差异。无并发症发生。结论:虽然一些常规治疗抵抗的女性最终在7天或10天的治疗过程中怀孕,但7天和10天的LE治疗组之间没有显着差异。需要进一步的广泛研究来验证这些发现。医疗保健专业人员在评估治疗方案时应考虑到这一趋势,特别是在个性化患者护理框架内,因为即使怀孕率的轻微提高也会产生显著影响。世界卫生组织伊朗试验注册注册号:IRCT20110908007513N19。
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引用次数: 0
Impact of Kinesio Taping on Pregnancy related Pelvic Girdle Pain and Disability. 肌内修贴贴对妊娠相关骨盆带疼痛和残疾的影响。
IF 0.6 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-01 Epub Date: 2025-08-07 DOI: 10.1007/s13224-025-02167-9
Bushra Bano, Aruna Nigam, Deepak Malhotra, Zeeshan Rais

Aim: To discover out the impact of Kinesio Taping (KT) in reduction of pain and disability experienced by pregnant females.

Method: Total 30 pregnant females in second trimester were recruited after fulfilling inclusion and exclusion criteria. They were randomized into 2 group. Experimental (A) received KT and Control group (B) sham KT. KT or sham KT was applied on day 1 and removed on day 5. Pain and disability were the results measures of the study. The pain levels were assessed by utilizing Visual Analogue Scale (VAS) on 1st day before treatment (BF) and after treatment (AF), 3rd day, 5th day and 7th day. Disability was evaluated using Oswestry Disability Index in Hindi Version, on day 1 and day 7.

Results: Preintervention both the groups were comparable regarding Pain and Oswestry Disability Index (ODI) scores. Post intervention experimental group had markedly decreased VAS and ODI from day 1 to day 7 (VAS Day 1 BF: 43.66 ± 17.31 Vs VAS Day 7: 26.13 ± 13.74; ODI Day 1: 31.80 ± 12.36 Vs ODI Day 7: 17.66 ± 7.30; p < 0.05). In control group VAS and ODI remained same between Day 1 & 7 (VAS Day 1 BF 31.93 ± 14.08, Vs VAS Day 7 32.46 ± 13.68;, ODI Day 1 22.13 ± 15.35 Vs ODI Day 7 22.00 ± 11.73).

Conclusions: KT can significantly reduce PGP and disability in pregnant females as compared to sham taping, measured by VAS and ODI scale respectively.

目的:探讨肌内效贴贴(KT)对减轻孕妇疼痛和残疾的影响。方法:选取符合纳入和排除标准的妊娠中期孕妇30例。随机分为两组。实验组(A)接受KT治疗,对照组(B)接受假KT治疗。第1天应用KT或假KT,第5天去除。疼痛和残疾是研究的结果测量。分别于治疗前第1天(BF)、治疗后第3天、第5天、第7天采用视觉模拟评分法(VAS)评定疼痛程度。在第1天和第7天使用印度语版Oswestry残疾指数进行残疾评估。结果:干预前两组在疼痛和Oswestry残疾指数(ODI)评分方面具有可比性。干预后实验组第1 ~ 7天VAS和ODI明显降低(VAS第1天BF: 43.66±17.31 Vs VAS第7天:26.13±13.74;ODI第1天:31.80±12.36 Vs ODI第7天:17.66±7.30;p结论:分别用VAS和ODI量表测量,与假手术相比,KT可显著降低妊娠女性PGP和残疾。
{"title":"Impact of Kinesio Taping on Pregnancy related Pelvic Girdle Pain and Disability.","authors":"Bushra Bano, Aruna Nigam, Deepak Malhotra, Zeeshan Rais","doi":"10.1007/s13224-025-02167-9","DOIUrl":"https://doi.org/10.1007/s13224-025-02167-9","url":null,"abstract":"<p><strong>Aim: </strong>To discover out the impact of Kinesio Taping (KT) in reduction of pain and disability experienced by pregnant females.</p><p><strong>Method: </strong>Total 30 pregnant females in second trimester were recruited after fulfilling inclusion and exclusion criteria. They were randomized into 2 group. Experimental (A) received KT and Control group (B) sham KT. KT or sham KT was applied on day 1 and removed on day 5. Pain and disability were the results measures of the study. The pain levels were assessed by utilizing Visual Analogue Scale (VAS) on 1st day before treatment (BF) and after treatment (AF), 3rd day, 5th day and 7th day. Disability was evaluated using Oswestry Disability Index in Hindi Version, on day 1 and day 7.</p><p><strong>Results: </strong>Preintervention both the groups were comparable regarding Pain and Oswestry Disability Index (ODI) scores. Post intervention experimental group had markedly decreased VAS and ODI from day 1 to day 7 (VAS Day 1 BF: 43.66 ± 17.31 Vs VAS Day 7: 26.13 ± 13.74; ODI Day 1: 31.80 ± 12.36 Vs ODI Day 7: 17.66 ± 7.30; p < 0.05). In control group VAS and ODI remained same between Day 1 & 7 (VAS Day 1 BF 31.93 ± 14.08, Vs VAS Day 7 32.46 ± 13.68;, ODI Day 1 22.13 ± 15.35 Vs ODI Day 7 22.00 ± 11.73).</p><p><strong>Conclusions: </strong>KT can significantly reduce PGP and disability in pregnant females as compared to sham taping, measured by VAS and ODI scale respectively.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 5","pages":"430-437"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12579075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Journal of Obstetrics and Gynecology of India
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