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Enzyme-Disrupting Chemicals as the Elephant in the Room for Infertility. 酶干扰化学物质是不孕症的 "大象"。
IF 0.7 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-08-01 Epub Date: 2023-08-10 DOI: 10.1007/s13224-023-01819-y
Geetha Balsarkar
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引用次数: 0
Menstrual Health Index: A Novel Approach to Assess Safe Menstrual Practices in Adolescents and Young Adults. 月经健康指数:评估青少年安全经期做法的新方法。
IF 0.7 Q3 Medicine Pub Date : 2023-06-01 Epub Date: 2023-03-15 DOI: 10.1007/s13224-022-01707-x
Shehla Jamal, Shravi Singh

Objective: To test the validity of the novel Menstrual Health Index (MHI) in order to assess safety of menstrual health and hygiene practices in adolescents and young adults.

Methods: This is a community-level prospective questionnaire-based study conducted in females between the age group of 11 and 23 years. The number of participants was 2860. The participants were asked to fill in the questionnaire pertaining to four components of menstrual health, viz., menstrual cycle, menstrual absorbents, psychosocial aspects and WASH component associated with menstruation. Based on the score assigned to each component, Menstrual Health Index was calculated. A score of 0-12 was considered poor, 12-24 was considered average, and 24-36 was considered good. Educational interventions were designed to improve the MHI in that particular population according to component analysis. After 3 months, MHI was rescored to see the improvement.

Results: A total of 3000 females were handed over the proforma and 2860 females participated.Among participants, 45.4% were from urban area, rest were from rural areas (35.6%) and slum areas (19%). Majority of the respondents were in the age group of 14-16 years (62%). Poor MHI (0-12 score) was seen in 48%, average score (13-24) was found in 37%, and good score was found in 15% participants. When individual components of MHI were assessed, it was found that, as high as 35% of the girls had limited accessibility to menstrual blood absorbents, 43% skipped school for more 4 times in a year, 26% suffered from severe dysmenorrhea, 32% reported difficulty in maintaining privacy while using WASH facilities and 54% were using clean sanitary pads as menstrual sanitation option. Best composite MHI was observed in urban areas, followed by rural and then slum area. In urban area and rural area, menstrual cycle component score was least. In rural area, sanitation component score was least and in slum area, WASH component scored the worst. Severe premenstrual dysphoric disorder was recorded in urban area, and maximum abstinence from school due to menstruation was seen in rural areas.An improvement in score was seen in 87% of the girls (93% individual and 87% composite), after 3 months of education and interventional strategies.

Conclusion: Menstrual health is not limited to cycle frequency and duration normalcy. It is a comprehensive subject, encompassing physical, social, psychological and geopolitical aspects. Assessing prevailing menstrual practices in a population, particularly in adolescents, is imperative to design IEC tools, and these objectives are aligned with SDG-M goals of Swachh Bharat Mission. MHI serves as a good screening tool to interrogate KAP in a particular area. Individual problems can also be addressed in a fruitful manner. Rights-based approach to provide essential infrastructure and provisions to promote safe and dignified practices t

目的测试新型月经健康指数(MHI)的有效性,以评估青少年月经健康和卫生习惯的安全性:这是一项以社区为基础的前瞻性问卷调查,调查对象为 11 至 23 岁的女性。参与人数为 2860 人。参与者被要求填写有关月经健康四个组成部分的问卷,即月经周期、月经吸收剂、社会心理方面以及与月经有关的讲卫生运动组成部分。根据每个部分的得分,计算出月经健康指数。0-12 分为差,12-24 分为一般,24-36 分为好。教育干预旨在根据成分分析结果改善特定人群的月经健康指数。3 个月后,对 MHI 进行复查,以了解改善情况:共向 3000 名女性发放了调查问卷,有 2860 名女性参与了调查。在参与者中,45.4% 来自城市地区,其余来自农村地区(35.6%)和贫民窟地区(19%)。大多数受访者的年龄在 14-16 岁之间(62%)。48%的受访者健康指数较差(0-12 分),37%的受访者健康指数一般(13-24 分),15%的受访者健康指数较好。在对 MHI 的各个组成部分进行评估时,发现高达 35% 的女孩很难获得经血吸收剂,43% 的女孩一年内逃学超过 4 次,26% 的女孩患有严重痛经,32% 的女孩表示在使用 WASH 设施时很难保持隐私,54% 的女孩使用清洁卫生护垫作为经期卫生设施。城市地区的综合 MHI 值最高,其次是农村地区,再次是贫民窟地区。在城市地区和农村地区,月经周期部分得分最低。在农村地区,卫生设施部分得分最低,而在贫民窟地区,讲卫生运动部分得分最差。经过 3 个月的教育和干预策略后,87% 的女孩(个人 93%,综合 87%)的得分有所改善:结论:月经健康并不局限于周期频率和持续时间是否正常。结论:月经健康并不局限于周期频率和持续时间是否正常,它是一个综合性问题,包括生理、社会、心理和地缘政治等方面。评估人群(尤其是青少年)中普遍存在的月经习俗对于设计 IEC 工具至关重要,这些目标与 "斯瓦赫-巴拉特使命 "的可持续发展目标-M 的目标相一致。月经健康指数(MHI)是一个很好的筛查工具,可用于调查特定地区的 KAP。个别问题也可以通过富有成效的方式得到解决。通过使用 MHI 等工具,可以帮助采取基于权利的方法,为青少年等弱势群体提供必要的基础设施和规定,以促进安全和有尊严的做法。
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引用次数: 0
Comparison of Hysterosalpingography and Laparoscopy in the Evaluation of Infertility: A Prospective Study. 子宫输卵管造影和腹腔镜检查在不孕不育评估中的比较:一项前瞻性研究。
IF 0.7 Q3 Medicine Pub Date : 2023-06-01 Epub Date: 2023-03-02 DOI: 10.1007/s13224-022-01728-6
Priyanka Sharma, S Sunita, Namrata Shrivastava, Meena Bhargava

Background: Worldwide one of the major problems of human reproduction that haunts men and women is infertility. Hysterosalpingography (HSG) and laparoscopy (LS) are the two most important modalities to evaluate infertility. Our aim is to compare the efficacy of both.

Methodology: This is a prospective study. One hundred and five females of both primary and secondary infertility together were included. Detailed history, examination and routine investigations were carried out. Tuberculosis polymerase chain reaction (TBPCR) was made from endometrial biopsy sample for all patients. Ovulation study was done by transvaginal ultrasonography. Hysterosalpingography and diagnostic laparoscopy were done.

Results: Out of 105 infertile patients, 51.42% were in 26-30 years group. 52.3% were from lower economic group. 55.23% presented between 1 to 5 years of infertility. Twelve patients had used contraception in the past. Sixteen patients were serologically positive. Twenty-nine patients were with positive TBPCR among 105 females. Fifty-four and fifty-six patients had patent tubes by HSG and laparoscopy, respectively. Uterine filling defects and congenital anomalies could be detected four times more by HSG than by laparoscopy. TO mass was detected only by laparoscopy. Bilateral spill was present in 66.6% by HSG and 67.6% by laparoscopy and unilateral spillage in 22.8% and 21.9%, respectively. The sensitivity, specificity and accuracy of HSG in predicting unilateral block taking laparoscopy as gold standard are 85%, 96.4% and 94.2%, respectively, and sensitivity and specificity of bilateral tubal block are 81.8% and 98%, respectively.

Conclusions: HSG and laparoscopy are not alternative, but complimentary in diagnosing tubal pathologies. HSG remains as primary screening procedure, but laparoscopy is gold standard.

背景:在世界范围内,困扰男性和女性的人类生殖的主要问题之一是不孕不育。子宫输卵管造影(HSG)和腹腔镜检查(LS)是评估不孕的两种最重要的方法。我们的目的是比较两者的疗效。方法:这是一项前瞻性研究。共有105名原发性和继发性不孕的女性被纳入研究。进行了详细的病史、检查和常规调查。对所有患者的子宫内膜活检样本进行结核聚合酶链反应(TBPCR)。通过阴道超声检查进行排卵研究。子宫输卵管造影和诊断性腹腔镜检查。结果:105例不孕患者中,26~30岁组占51.42%。52.3%来自低经济阶层。55.23%的患者在1至5年内出现不孕。过去有12名患者使用过避孕措施。16名患者血清呈阳性。在105名女性中,29名患者的TBPCR呈阳性。分别有54名和56名患者通过HSG和腹腔镜进行了未闭管检查。HSG检查子宫充盈缺损和先天性畸形的检出率是腹腔镜检查的四倍。TO肿块仅通过腹腔镜检查发现。HSG和腹腔镜检查的双侧渗漏分别为66.6%和67.6%,单侧渗漏分别为22.8%和21.9%。以腹腔镜为金标准的HSG预测单侧输卵管阻塞的敏感性、特异性和准确性分别为85%、96.4%和94.2%,双侧输卵管阻塞敏感性和特异性分别为81.8%和98%。结论:HSG和腹腔镜检查在诊断输卵管病变方面不是可替代的,而是互补的。HSG仍然是主要的筛查程序,但腹腔镜检查是金标准。
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引用次数: 0
Impact of COVID-19 Pandemic on Non-COVID-19 Maternal Mortalities in a Tertiary Health Care Center of North India. COVID-19大流行对印度北部三级卫生保健中心非COVID-19孕产妇死亡率的影响
IF 0.7 Q3 Medicine Pub Date : 2023-06-01 DOI: 10.1007/s13224-022-01734-8
Amrita Chaurasia, Divya Gupta, Kumari Shweta, Yashi Srivastava

Introduction: While dealing with the COVID-19-related morbidities and mortalities in general, its adverse impact on non-COVID-19 maternal mortalities was completely forgotten so our aim is to study the adverse consequences of the COVID-19 pandemic on non-COVID-19 hospital births and non-COVID-19 maternal mortalities.

Methodology: Retrospective observational study was done in the Department of Obstetrics and Gynecology, Swaroop Rani Hospital, Prayagraj, to compare the non-COVID-19 hospital births, referrals, and non-COVID-19 maternal mortalities during 15 months of pre-pandemic period (March 2018 to May 2019) and 15 months of pandemic period (March 2020 to May 2021 period) and to assess their relation to GRSI using chi-square test, paired T test and Pearson's Correlation Coefficient.

Result: The total non-COVID-19 hospital births decreased by 4.32% in pandemic period as compared to pre-pandemic period. Monthly hospital births decreased drastically, to 32.7% during the end of the first pandemic wave and to 60.17% during the second wave. 67% increase in the total referral and a significant decrease in the quality of referral leading to significantly higher non-COVID-19 maternal mortality figures (p value 0.00003) during the pandemic period. Leading causes of mortalities were uterine rupture (p value 0.00001), septic abortion (p value 0.0001), primary postpartum hemorrhage (p value 0.002) and preeclampsia (p value 0.003).

Conclusion: While the world is talking only about COVID deaths, increased non-COVID-19 maternal mortalities during the COVID pandemic need equal attention and call for more stringent government guidelines for the care of non-COVID-19 pregnant women as well during the pandemic period.

导语:在处理与COVID-19相关的总体发病率和死亡率时,完全忘记了其对非COVID-19孕产妇死亡率的不利影响,因此我们的目的是研究COVID-19大流行对非COVID-19医院分娩和非COVID-19孕产妇死亡率的不利后果。方法:在Prayagraj Swaroop Rani医院妇产科进行回顾性观察研究,比较大流行前15个月(2018年3月至2019年5月)和大流行期间15个月(2020年3月至2021年5月)的非covid -19住院分娩、转诊和非covid -19孕产妇死亡率,并使用卡方检验、配对T检验和Pearson相关系数评估其与GRSI的关系。结果:大流行期间非covid -19住院分娩总数较大流行前下降4.32%。每月住院分娩率急剧下降,在第一波大流行结束时降至32.7%,在第二波大流行结束时降至60.17%。转诊总人数增加67%,转诊质量显著下降,导致大流行期间非covid -19孕产妇死亡率显著上升(p值0.00003)。死亡原因主要为子宫破裂(p值0.00001)、败血性流产(p值0.0001)、产后原发性出血(p值0.002)和先兆子痫(p值0.003)。结论:虽然世界只在谈论COVID-19死亡,但在COVID-19大流行期间,非COVID-19孕产妇死亡率的增加也需要得到同样的关注,并呼吁政府在大流行期间制定更严格的非COVID-19孕妇护理指南。
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引用次数: 1
Pituitrin Injection before Hysteroscopic Curettage for Treating Type I Cesarean Scar Pregnancy in Comparison with Uterine Artery Embolization: A Retrospective Study. 宫腔镜刮除术前注射垂体后叶素治疗Ⅰ型剖宫产瘢痕妊娠与子宫动脉栓塞的比较:回顾性研究。
IF 0.7 Q3 Medicine Pub Date : 2023-06-01 Epub Date: 2022-12-18 DOI: 10.1007/s13224-022-01724-w
Juveria Rahman, Yixuan Qiu, Xiong Yuan, Sajjaad H Kassim, Tonghui Ji, Huihua Dai

Background: The effectiveness and safety of pituitrin injection coupled with hysteroscopy and suction curettage as treatment for type I cesarean scar pregnancy (CSP) have not been studied enough in the literature, by comparing it to uterine artery embolization (UAE) followed by suction curettage we aim to determine its efficacy.

Materials and methods: Data of 53 patients (the PIT group) with type I CSP treated with pituitrin injection combined with hysteroscopic suction curettage and 137 patients (the UAE group) with type I CSP treated with UAE followed by suction curettage were collected in retrospect. The clinical data were analyzed statistically to compare the efficacy and safety between the two groups.

Results: The PIT group had a shorter duration of postoperative vaginal bleeding, postoperative hospitalization, and overall hospitalization length (P < 0.05). The PIT group had lower overall hospitalization costs and a lower rate of adverse events than the UAE group (P < 0.05). There was no significant difference between the two groups in terms of treatment success rate, the average length of operation, blood loss during the procedure, time when serum β-hCG returned to normal range, and menstrual recovery time after hospital release (P > 0.05).

Conclusion: UAE and pituitrin injection followed by hysteroscopic suction curettage are good choices for type I CSP treatment. However, pituitrin injection with hysteroscopic suction curettage outperforms UAE followed by suction curettage. Thus, pituitrin injection may be an option of high priority for type I CSP.

背景:垂体后叶素注射联合宫腔镜和刮除术治疗I型剖宫产瘢痕妊娠(CSP)的有效性和安全性在文献中研究不足,通过与子宫动脉栓塞(UAE)和刮除法的比较,我们旨在确定其疗效。材料与方法:回顾性分析53例(PIT组)I型CSP患者应用垂体后叶素注射联合宫腔镜吸刮术治疗的资料,以及137例(UAE组)Ⅰ型CSP患者采用UAE联合吸刮术的资料。对临床数据进行统计学分析,比较两组的疗效和安全性。结果:PIT组术后阴道出血持续时间短,住院时间短,总住院时间短(P P β-hCG恢复正常范围,出院后月经恢复时间(P > 结论:阿联酋联合垂体后叶素注射联合宫腔镜刮除术是治疗Ⅰ型CSP的良好选择。然而,注射垂体后叶素联合宫腔镜刮除术的疗效优于阿联酋刮除术。因此,垂体后叶素注射可能是I型CSP的高优先级选择。
{"title":"Pituitrin Injection before Hysteroscopic Curettage for Treating Type I Cesarean Scar Pregnancy in Comparison with Uterine Artery Embolization: A Retrospective Study.","authors":"Juveria Rahman, Yixuan Qiu, Xiong Yuan, Sajjaad H Kassim, Tonghui Ji, Huihua Dai","doi":"10.1007/s13224-022-01724-w","DOIUrl":"10.1007/s13224-022-01724-w","url":null,"abstract":"<p><strong>Background: </strong>The effectiveness and safety of pituitrin injection coupled with hysteroscopy and suction curettage as treatment for type I cesarean scar pregnancy (CSP) have not been studied enough in the literature, by comparing it to uterine artery embolization (UAE) followed by suction curettage we aim to determine its efficacy.</p><p><strong>Materials and methods: </strong>Data of 53 patients (the PIT group) with type I CSP treated with pituitrin injection combined with hysteroscopic suction curettage and 137 patients (the UAE group) with type I CSP treated with UAE followed by suction curettage were collected in retrospect. The clinical data were analyzed statistically to compare the efficacy and safety between the two groups.</p><p><strong>Results: </strong>The PIT group had a shorter duration of postoperative vaginal bleeding, postoperative hospitalization, and overall hospitalization length (<i>P</i> < 0.05). The PIT group had lower overall hospitalization costs and a lower rate of adverse events than the UAE group (<i>P</i> < 0.05). There was no significant difference between the two groups in terms of treatment success rate, the average length of operation, blood loss during the procedure, time when serum <i>β</i>-hCG returned to normal range, and menstrual recovery time after hospital release (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>UAE and pituitrin injection followed by hysteroscopic suction curettage are good choices for type I CSP treatment. However, pituitrin injection with hysteroscopic suction curettage outperforms UAE followed by suction curettage. Thus, pituitrin injection may be an option of high priority for type I CSP.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"73 3","pages":"229-234"},"PeriodicalIF":0.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9653949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Feto-maternal Outcomes Among Various BMI Groups As Per Asia Pacific Standards: An Observational Retrospective Comparative Study in a Private Tertiary Care Center in Delhi. 根据亚太地区标准,不同BMI组的胎儿-母亲结局比较:德里一家私立三级护理中心的一项观察性回顾性比较研究。
IF 0.7 Q3 Medicine Pub Date : 2023-06-01 Epub Date: 2023-01-07 DOI: 10.1007/s13224-022-01739-3
Arpita De, Aruna Nigam, Sumedha Sharma, Arifa Anwar

Objective: To compare the feto-maternal outcomes among various BMI groups as per Asia Pacific Standards.

Method: This is a retrospective non-interventional observational study on 1396 antenatal women with singleton pregnancy. Their BMI based on pre-pregnancy weight was calculated and the women were divided into various groups as per Asia Pacific standards for BMI classification. Details of associated morbidities and delivery outcomes were noted in a pre-structured proforma and a comparison was made among the various groups using Chi square test. A p value of < 0.05 was taken as significant.

Results: Among the 1396 women under study, 10.6% were underweight, 36% had normal weight, 21% were overweight while 32% were obese or very obese. There was a significant association of low BMI with preterm labor (p value 0.03) and fetal growth restriction (p value < 0.01). Overweight and obese women were found to be more prone to hypertensive disorders of pregnancy (p value- 0.002), gestational diabetes (p value- 0.003) and overweight women were more prone to cholestasis of pregnancy (p value 0.03). The women with higher BMI had a significantly higher requirement of induction of labor (p value-0.0002). There was significant increased number of babies more than 90th percentile in overweight and obese women (p value 0.003). However, there was no change in Neonatal ICU admissions (p value 0.85) or neonatal mortality.

Conclusion: Asia Pacific references should be used for studies related to all studies on BMI and pregnancy. All women having BMI outside the normal BMI spectrum are at increased risk of antenatal and postnatal complications. Early identification of such women will enable careful evaluation and counseling to improve the reproductive outcome and feto-maternal health.

目的:根据亚太地区标准,比较不同BMI组的胎儿-母体结局。方法:这是一项对1396名单胎妊娠产前妇女的回顾性非干预性观察性研究。根据孕前体重计算她们的BMI,并根据亚太地区BMI分类标准将这些女性分为不同的组。在预先构建的形式表中记录了相关疾病和分娩结果的细节,并使用卡方检验对各组进行了比较。的p值 结果:在接受研究的1396名女性中,10.6%体重不足,36%体重正常,21%超重,32%肥胖或非常肥胖。低BMI与早产(p值0.03)和胎儿生长受限(p值 p值0.002)、妊娠期糖尿病(p值-0.003)和超重女性更容易出现妊娠期胆汁淤积(p值0.03)。BMI越高的女性对引产的要求越高(p值=0.0002)。超重和肥胖女性的婴儿数量显著增加,超过第90百分位(p值0.003)。然而,新生儿ICU入院率(p值0.85)或新生儿死亡率没有变化。结论:亚太地区的参考文献应用于与BMI和妊娠相关的所有研究。所有BMI在正常BMI范围之外的女性,产前和产后并发症的风险都会增加。对这些妇女的早期识别将有助于进行仔细的评估和咨询,以改善生殖结果和母婴健康。
{"title":"Comparison of Feto-maternal Outcomes Among Various BMI Groups As Per Asia Pacific Standards: An Observational Retrospective Comparative Study in a Private Tertiary Care Center in Delhi.","authors":"Arpita De, Aruna Nigam, Sumedha Sharma, Arifa Anwar","doi":"10.1007/s13224-022-01739-3","DOIUrl":"10.1007/s13224-022-01739-3","url":null,"abstract":"<p><strong>Objective: </strong>To compare the feto-maternal outcomes among various BMI groups as per Asia Pacific Standards.</p><p><strong>Method: </strong>This is a retrospective non-interventional observational study on 1396 antenatal women with singleton pregnancy. Their BMI based on pre-pregnancy weight was calculated and the women were divided into various groups as per Asia Pacific standards for BMI classification. Details of associated morbidities and delivery outcomes were noted in a pre-structured proforma and a comparison was made among the various groups using Chi square test. A <i>p</i> value of < 0.05 was taken as significant.</p><p><strong>Results: </strong>Among the 1396 women under study, 10.6% were underweight, 36% had normal weight, 21% were overweight while 32% were obese or very obese. There was a significant association of low BMI with preterm labor (<i>p</i> value 0.03) and fetal growth restriction (<i>p</i> value < 0.01). Overweight and obese women were found to be more prone to hypertensive disorders of pregnancy (<i>p</i> value- 0.002), gestational diabetes (<i>p</i> value- 0.003) and overweight women were more prone to cholestasis of pregnancy (<i>p</i> value 0.03). The women with higher BMI had a significantly higher requirement of induction of labor (<i>p</i> value-0.0002). There was significant increased number of babies more than 90th percentile in overweight and obese women (<i>p</i> value 0.003). However, there was no change in Neonatal ICU admissions (<i>p</i> value 0.85) or neonatal mortality.</p><p><strong>Conclusion: </strong>Asia Pacific references should be used for studies related to all studies on BMI and pregnancy. All women having BMI outside the normal BMI spectrum are at increased risk of antenatal and postnatal complications. Early identification of such women will enable careful evaluation and counseling to improve the reproductive outcome and feto-maternal health.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"73 3","pages":"223-228"},"PeriodicalIF":0.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9653952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Presentation of Gastrointestinal Stromal Tumor as an Ovarian Mass: A Diagnostic Dilemma. 异常表现为卵巢肿块的胃肠道间质瘤:诊断难题。
IF 0.7 Q3 Medicine Pub Date : 2023-06-01 Epub Date: 2023-03-17 DOI: 10.1007/s13224-023-01743-1
Jyoti Baghel, Hema Pant, Amit Kumar Singh, Rajneesh Rawat
{"title":"An Unusual Presentation of Gastrointestinal Stromal Tumor as an Ovarian Mass: A Diagnostic Dilemma.","authors":"Jyoti Baghel, Hema Pant, Amit Kumar Singh, Rajneesh Rawat","doi":"10.1007/s13224-023-01743-1","DOIUrl":"10.1007/s13224-023-01743-1","url":null,"abstract":"","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"73 3","pages":"282-284"},"PeriodicalIF":0.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9659996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can Medical Nutrition Therapy Affect Feto-Maternal Outcomes in Gestational Glucose Intolerance: An Open-Label Pilot Randomized Control Trial in World's Diabetes Capital. 药物营养治疗是否会影响妊娠期血糖不耐受的胎儿-母亲结局:世界糖尿病之都的一项开放标签试点随机对照试验。
IF 0.7 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-06-01 Epub Date: 2022-12-08 DOI: 10.1007/s13224-022-01722-y
Namrata Kumar, Vinita Das, Anveshika Srivastava, Anjoo Agarwal, Amita Pandey, Smriti Agarwal

Introduction: Gestational diabetes is defined as the carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. Gestational glucose intolerance (GGI) is used to indicate pregnant women whose 2-h postprandial glucose is > 120 mg/dl and below 140 mg/dl (Diabetes in Pregnancy Study Group of India, DIPSI criteria).

Aim: This study was planned to see whether intervention in GGI group helps to improve feto-maternal outcomes.

Methodology: This open-label randomized control trial was conducted in Department of Obstetrics and Gynaecology of King George's Medical University, Lucknow. Inclusion criteria were all the antenatal women attending the antenatal clinic and diagnosed as GGI, and exclusion criteria were overt diabetes.

Results: Total of 1866 antenatal women were screened, and among them, 220 (11.8%) women were diagnosed as gestational diabetes; 412 (22.1%) women were diagnosed as GGI. The mean fasting blood sugars in the women with GGI who had medical nutrition therapy were much lower than the women with GGI who did not have any intervention. The present study showed the women with GGI had higher complications like polyhydramnios, PPROM, foetal growth restriction, macrosomia, preeclampsia, preterm labour and vaginal candidiasis more in the women with GGI as compared to euglycaemic women.

Conclusion: The present study of nutritional intervention in GGI group has shown trend towards lesser complication if we start medical nutrition therapy reflected by delayed development of GDM and less neonatal hypoglycaemia and hyperbilirubinemia.

引言:妊娠期糖尿病是指在妊娠期发病或首次识别的不同严重程度的碳水化合物不耐受。妊娠期葡萄糖不耐受(GGI)用于指餐后2小时血糖为 > 120 mg/dl及以下140 mg/dl(印度妊娠期糖尿病研究组,DIPSI标准)。目的:本研究旨在了解GGI组的干预是否有助于改善胎儿至母体的结局。方法:这项开放标签随机对照试验在勒克瑙乔治国王医科大学妇产科进行。纳入标准为所有参加产前诊所并被诊断为GGI的产前妇女,排除标准为显性糖尿病。结果:共筛查1866名产前妇女,其中220名(11.8%)妇女被诊断为妊娠期糖尿病;412名(22.1%)女性被诊断为GGI。接受药物营养治疗的GGI妇女的平均空腹血糖远低于未接受任何干预的GGI女性。本研究表明,与正常血糖女性相比,GGI女性有更高的并发症,如羊水过多、PPROM、胎儿生长受限、巨大儿、先兆子痫、早产和阴道念珠菌感染。结论:目前对GGI组营养干预的研究表明,如果我们开始药物营养治疗,并发症会减少,这反映在GDM的延迟发展以及新生儿低血糖和高胆红素血症的减少。
{"title":"Can Medical Nutrition Therapy Affect Feto-Maternal Outcomes in Gestational Glucose Intolerance: An Open-Label Pilot Randomized Control Trial in World's Diabetes Capital.","authors":"Namrata Kumar, Vinita Das, Anveshika Srivastava, Anjoo Agarwal, Amita Pandey, Smriti Agarwal","doi":"10.1007/s13224-022-01722-y","DOIUrl":"10.1007/s13224-022-01722-y","url":null,"abstract":"<p><strong>Introduction: </strong>Gestational diabetes is defined as the carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. Gestational glucose intolerance (GGI) is used to indicate pregnant women whose 2-h postprandial glucose is > 120 mg/dl and below 140 mg/dl (Diabetes in Pregnancy Study Group of India, DIPSI criteria).</p><p><strong>Aim: </strong>This study was planned to see whether intervention in GGI group helps to improve feto-maternal outcomes.</p><p><strong>Methodology: </strong>This open-label randomized control trial was conducted in Department of Obstetrics and Gynaecology of King George's Medical University, Lucknow. Inclusion criteria were all the antenatal women attending the antenatal clinic and diagnosed as GGI, and exclusion criteria were overt diabetes.</p><p><strong>Results: </strong>Total of 1866 antenatal women were screened, and among them, 220 (11.8%) women were diagnosed as gestational diabetes; 412 (22.1%) women were diagnosed as GGI. The mean fasting blood sugars in the women with GGI who had medical nutrition therapy were much lower than the women with GGI who did not have any intervention. The present study showed the women with GGI had higher complications like polyhydramnios, PPROM, foetal growth restriction, macrosomia, preeclampsia, preterm labour and vaginal candidiasis more in the women with GGI as compared to euglycaemic women.</p><p><strong>Conclusion: </strong>The present study of nutritional intervention in GGI group has shown trend towards lesser complication if we start medical nutrition therapy reflected by delayed development of GDM and less neonatal hypoglycaemia and hyperbilirubinemia.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"73 3","pages":"208-213"},"PeriodicalIF":0.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10301148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postpartum Collapse Subsequent to Catatonia in a Female with COVID-19 Infection: a Rare Entity Visited. 一名感染新冠肺炎的女性在患卡塔尼亚后产后塌陷:一个罕见的实体就诊。
IF 0.7 Q3 Medicine Pub Date : 2023-06-01 Epub Date: 2023-01-10 DOI: 10.1007/s13224-022-01737-5
Bharti Joshi, Swapnajeet Sahoo, G R V Prasad, Vanita Suri, Varun Mahajan, Sandeep Grover, Rinne Brar, Seema Chopra

Postpartum collapse is a life-threatening condition caused by obstetrical and non-obstetrical events. In this case report, we discuss a case of postpartum collapse in COVID-19-positive woman who required intensive care and mechanical ventilation for two days. After confusing collision of many provisional diagnoses soldiering for three days, she was ultimately diagnosed with malignant catatonia. Targeted therapy with lorazepam challenge resulted in drastic improvement, and she was discharged with her baby in healthy condition.

产后虚脱是由产科和非产科事件引起的危及生命的情况。在本病例报告中,我们讨论了一例需要重症监护和机械通气两天的COVID-19阳性女性产后虚脱的病例。在经历了三天的混乱冲突后,她最终被诊断为恶性紧张症。劳拉西泮激发靶向治疗后病情得到了显著改善,她出院时带着健康的孩子。
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引用次数: 0
A Prospective Multi-centric Study of Acceptance, Insertion and Follow-Up of Postpartum Insertions of IUCD. 一项前瞻性多中心研究对宫内节育器产后插入的接受、插入和随访。
IF 0.7 Q3 Medicine Pub Date : 2023-06-01 Epub Date: 2023-02-02 DOI: 10.1007/s13224-022-01738-4
Shobha N Gudi, Jyoti Sachdeva, Renu Manchanda, Mrinalini Mani, Shailja Rani Ranjan Sinha, Sushma Sinha, Poonam Shivkumar, Reena J Wani, Nishi Garg, Sanjivani Wanjari, Bharati Sharma, Pramila Yadav, Neha Gangane

Purpose of the study: The unmet need for contraception in the postpartum period is a major challenge in our country. Unintended pregnancies are highest in the first year after birth, and postpartum IUCD insertion is an effective way to counter this problem. This study was planned to build up data for acceptance and follow-up of postpartum IUCD insertions.

Methods: The present study has included data of PPIUCD insertions and follow-up from seven institutions over a period of 6 months. The case recruitment lasted for 3 months, including only those who had PPIUCD insertions in this period, and they were followed up for a period of 6 months. The follow-up of patients was at 6 weeks and 6 months. All issues were addressed including side effects, expulsions, myths surrounding the device, etc., along with routine postnatal care.

Results and conclusion: There were 5227 deliveries and 1895 insertions. The acceptance rate was 36%, and a follow-up at 6 weeks and 6 months showed up an expulsion rate of approximately 4% and a removal rate of 5%. Overall, at the end of 6 months we have a continuation rate of 90%. This shows that a dedicated approach to postpartum contraception will definitely bring down incidence of unintended pregnancies.

研究目的:产后避孕需求未得到满足是我国面临的一大挑战。意外怀孕在出生后的第一年最高,产后插入宫内节育器是解决这一问题的有效方法。本研究旨在为产后宫内节育器插入的接受和随访建立数据。方法:本研究包括7个机构在6个月内的PPIUCD插入和随访数据。病例招募持续了3个月,仅包括在此期间插入PPIUCD的患者,并随访了6个月。患者的随访时间为6周和6个月。所有问题都得到了解决,包括副作用、驱逐、围绕该设备的神话等,以及常规的产后护理。结果与结论:分娩5227例,插入1895例。接受率为36%,6周和6个月的随访显示,排出率约为4%,去除率为5%。总的来说,在6个月结束时,我们的延续率为90%。这表明,专门的产后避孕方法肯定会降低意外怀孕的发生率。
{"title":"A Prospective Multi-centric Study of Acceptance, Insertion and Follow-Up of Postpartum Insertions of IUCD.","authors":"Shobha N Gudi,&nbsp;Jyoti Sachdeva,&nbsp;Renu Manchanda,&nbsp;Mrinalini Mani,&nbsp;Shailja Rani Ranjan Sinha,&nbsp;Sushma Sinha,&nbsp;Poonam Shivkumar,&nbsp;Reena J Wani,&nbsp;Nishi Garg,&nbsp;Sanjivani Wanjari,&nbsp;Bharati Sharma,&nbsp;Pramila Yadav,&nbsp;Neha Gangane","doi":"10.1007/s13224-022-01738-4","DOIUrl":"10.1007/s13224-022-01738-4","url":null,"abstract":"<p><strong>Purpose of the study: </strong>The unmet need for contraception in the postpartum period is a major challenge in our country. Unintended pregnancies are highest in the first year after birth, and postpartum IUCD insertion is an effective way to counter this problem. This study was planned to build up data for acceptance and follow-up of postpartum IUCD insertions.</p><p><strong>Methods: </strong>The present study has included data of PPIUCD insertions and follow-up from seven institutions over a period of 6 months. The case recruitment lasted for 3 months, including only those who had PPIUCD insertions in this period, and they were followed up for a period of 6 months. The follow-up of patients was at 6 weeks and 6 months. All issues were addressed including side effects, expulsions, myths surrounding the device, etc., along with routine postnatal care.</p><p><strong>Results and conclusion: </strong>There were 5227 deliveries and 1895 insertions. The acceptance rate was 36%, and a follow-up at 6 weeks and 6 months showed up an expulsion rate of approximately 4% and a removal rate of 5%. Overall, at the end of 6 months we have a continuation rate of 90%. This shows that a dedicated approach to postpartum contraception will definitely bring down incidence of unintended pregnancies.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"73 3","pages":"254-261"},"PeriodicalIF":0.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9647543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Journal of Obstetrics and Gynecology of India
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