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Title: The Effect of Distance Teaching to Mothers on Primary School Boys’ Sleep Habits Related to Computer Games: A Quasi-experimental Study 题目:母亲远程教学对小学生电脑游戏相关睡眠习惯的影响:一项准实验研究
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-10-20 DOI: 10.22038/IJP.2021.60059.4663
Fereshteh Dastres, M. Ghaljeh, Alia Jalalodini, F. Ghaljaei
Background:Computer games have often been considered to have a negative impact on the sleep of children. The aim study was to determine the effect of distance teaching to mothers on sleep habits related to computer games of primary school boys of Zahedan in 2020.Materials and Methods:The present quasi-experimental study was carried out on primary school boys students. 144 students were randomly selected in two groups of intervention and control.Data collection tools included the Child Sleep Habits and demographic information Questionnaire.If the student was in the intervention group,before the intervention,the researcher held a face-to-face meeting with his mother to complete the questionnaire.Then,created a group for mothers in Telegram and WhatsApp,The intervention was made for 4weeks,the researcher sent a text and avideo three times a week to students’mothers based on the content of education.8weeks after,the Sleep Habits Questionnaire was completed by the mothers.If the student was assigned to the control group,demographic information and Sleep Habits Questionnaire were completed by the mothers to begin the pre-test.No intervention was made for this group.The post-test was completed after 8 weeks by the mothers.Data analysis was performed through IBM SPSS.Results:The results showed that the mean and standard deviation of the sleep habits score and its dimensions in intervention and control groups had no significant difference(P>0.05)before intervention.However,after intervention,the sleep habits score and its dimensions had significant differences(P<0.05). Conclusion:maintaining the physical and mental health of students is an important responsibility of pediatric nurses and parents.It is suggested that teaching sleep habits to mothers should be considered.
背景:电脑游戏经常被认为对儿童的睡眠有负面影响。本研究旨在确定母亲远程教学对2020年扎黑丹小学男生电脑游戏相关睡眠习惯的影响。材料和方法:本研究以小学男生为对象进行准实验研究。144名学生被随机分为干预组和对照组。数据收集工具包括儿童睡眠习惯和人口统计信息问卷。如果学生在干预组,在干预前,研究人员与母亲举行面对面会议以完成问卷。然后,在Telegram和WhatsApp上为母亲们创建了一个小组。干预为期4周,研究人员根据教育内容每周向学生母亲发送三次短信和视频。8周后,母亲们完成了睡眠习惯问卷。如果将学生分配到对照组,则由母亲填写人口统计信息和睡眠习惯问卷,开始预测试。该组未进行干预。8周后,母亲们完成了产后测试。结果:干预组与对照组睡眠习惯评分及其维度的平均值和标准差在干预前无显著性差异(P>0.05)。结论:维护学生身心健康是儿科护士和家长的重要责任。建议应该考虑向母亲传授睡眠习惯。
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引用次数: 0
Herbal treatments for asthma, according to Avicenna 根据阿维森纳的说法,草药治疗哮喘
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-10-12 DOI: 10.22038/IJP.2021.58082.4553
S. Sadr, Narges Kaveh, K. Agin, R. Choopani, Shahpar Kaveh, Hanieh Tahermohammadi
AbstractBackground and objectives: Conventional therapies using herbal medicine to treat asthma are employed by practitioners in Iran. The use of herbal medicine for asthma is rooted in traditional knowledge. Scientific evaluation of these historical documents could be valuable to find new potential applications in conventional medicine. Traditional Persian Medicine (TPM), which is widely known with the manuscripts of Avicenna and Rhazes, is one of the most ancient medical set of beliefs.Methods: In this study, firstly we introduce a series of medicinal plants that would be enormously valuable for treating asthma on the basis of Avicenna (The Canon of Medicine by Avicenna). After that, we review medicinal plants properties found in the pharmacological studies from electronic databases and then discuss their mechanism of action in asthma. For a detailed review, relevant abstracts and articles related to the above-mentioned areas were selected, including review articles on the subjects, along with clinical trial studies in animals and humans.Results: The physicians of ancient Iran such as Avicenna treated asthma patients with a variety of medicinal herbs. Some of these herbs are currently used, while others have the potential to be used in the future of asthma management.Conclusions: This study demonstrates that the investigated plants are consistent with new studies; therefore, different components of these herbs can be utilized in manufacturing new drugs. Future clinical studies on healthy volunteers and also patients suffering from asthma and reactive airway disease are compulsory to confirm the effectuality of these plants as complementary interventions in asthma.
背景和目的:伊朗的医生采用传统的草药治疗哮喘。使用草药治疗哮喘源于传统知识。对这些历史文献的科学评估可能有助于在传统医学中找到新的潜在应用。传统波斯医学(TPM)是最古老的医学信仰之一,因阿维森纳和雷兹的手稿而广为人知。方法:在本研究中,我们首先介绍了一系列在阿维森纳(阿维森纳的医学经典)的基础上对治疗哮喘具有巨大价值的药用植物。之后,我们从电子数据库中回顾了药理学研究中发现的药用植物特性,然后讨论了它们在哮喘中的作用机制。为了进行详细的综述,选择了与上述领域相关的相关摘要和文章,包括关于受试者的综述文章,以及动物和人类的临床试验研究。结果:阿维森纳等古代伊朗医生用多种草药治疗哮喘患者。其中一些草药目前正在使用,而另一些则有可能在未来的哮喘管理中使用。结论:本研究表明,所研究的植物与新的研究一致;因此,这些草药的不同成分可以用于制造新药。未来必须对健康志愿者以及患有哮喘和反应性气道疾病的患者进行临床研究,以确认这些植物作为哮喘补充干预措施的有效性。
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引用次数: 0
Dietary Intake of Macro- and Micronutrients in children: Comparison with Reference Values 儿童膳食中常量和微量营养素的摄入量:与参考值的比较
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-10-07 DOI: 10.22038/IJP.2021.58272.4561
Abdolhamid Jafari Nodoushan, S. J. Sayedi, A. Najarzadeh, M. Karimi, A. Golzar
Background: One of the most important factors in maintaining and improving children's health is the quality of diet.Objectives: The aim of this study was to determine the micro and macro nutrient intakes in children aged less than five years old with malnutrition.Methods: The cross-sectional study included 75 under-five children referring to primary health care center in Taft. Children classified in two groups by nutritional status according to a variety of anthropometric indicators. Food intake was assessed using 24 hour food recalls and then was compared to the recommended daily amount (RDA). Anthropometric measures of age, height/length and weight and measurements head circumference were obtained and compared with reference anthropometric indices to assess nutritional statusResults: The subjects consisted of 41 boys and 34 girls who were 36 (48%) in the malnourished group and 39 (52%) in another group. The analysis of food intake indicated that most micronutrients were within recommendations, except for calcium, zinc, iron and folate (P<0. 05). The intake of macronutrients, was above recommendations and energy intake was in the general appropriate level.Conclusion: The findings of the study indicated that the appropriate level of macronutrients intake was used and the problem was mainly existed in micronutrients’ consumption. Based on the results we recommended planning for nutrition education program.
背景:维持和改善儿童健康的最重要因素之一是饮食质量。目的:本研究的目的是确定五岁以下营养不良儿童的微观和宏观营养素摄入量。方法:横断面研究包括75名5岁以下儿童,他们被送往塔夫脱的初级卫生保健中心。根据各种人体测量指标,根据营养状况将儿童分为两组。食物摄入量通过24小时食物召回进行评估,然后与推荐每日摄入量(RDA)进行比较。获得了年龄、身高/身高和体重的人体测量值以及头围测量值,并将其与参考人体测量指数进行比较,以评估营养状况。结果:受试者包括41名男孩和34名女孩,营养不良组为36名(48%),另一组为39名(52%)。食物摄入量分析表明,除钙、锌、铁和叶酸外,大多数微量营养素都在推荐范围内(P<0。05)。大量营养素的摄入量高于建议,能量摄入处于一般适当水平。结论:研究结果表明,摄入了适当水平的常量营养素,问题主要存在于微量营养素的摄入方面。根据研究结果,我们建议制定营养教育计划。
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引用次数: 0
Using Bagging Neural Network to Predict the Factors Affecting Neonatal Mortality 利用Bagging神经网络预测新生儿死亡率影响因素
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-10-06 DOI: 10.22038/IJP.2021.57861.4538
Somayeh Heshmat Alvandi, M. Ghojazadeh, M. Heidarzadeh, S. Dastgiri, Hooman Nateghian
BackgroundThe rate of neonatal mortality is one of the main indices of health, treatment, and development in societies. It reflects the quality of nutrition and life of mothers as well as the rate of healthcare services that mothers and children are provided with by societies. This study aimed to identify the factors affecting neonatal mortality by using a bagging neural network in Rapidminer Software. Materials and MethodsThe study was conducted on 8053 births (including 1605 death cases and 6448 control cases) all over Iran in 2015. Factors such as maternal risk factors, mother’s age, gestational age, child gender, birth weight, birth order, and congenital anomalies were utilized as the predictor variables of the bagging neural network. Some criteria including the area under the ROC curve, as well as the property and sensitivity of the bagging neural network, were compared with the neural network model. And the bagging neural network with 99.24% precision rate enjoyed better results in predicting those factors affecting neonatal mortality.ResultsOur suggested method revealed that gestational age is the most significant predictor factor of a neonate's status at birth time. Besides, 1-minute Apgar, need for resuscitation, 5-minute Apgar, birth weight, congenital anomalies, and birth order, as well as diabetes and preeclampsia in mothers, were identified as the most significant predictor factors after the gestational age.ConclusionFactors discovered in this study can be considered to decrease neonatal mortality. This can help the health of mothers’ community, optimize healthcare services, and development of societies.
新生儿死亡率是社会健康、治疗和发展的主要指标之一。它反映了母亲的营养和生活质量,以及社会为母亲和儿童提供的医疗服务的比率。本研究旨在使用Rapidminer软件中的bagging神经网络来确定影响新生儿死亡率的因素。材料和方法本研究对2015年伊朗全国8053例新生儿(包括1605例死亡病例和6448例对照病例)进行了研究。母亲风险因素、母亲年龄、胎龄、儿童性别、出生体重、出生顺序和先天性畸形等因素被用作bagging神经网络的预测变量。将一些标准,包括ROC曲线下的面积,以及bagging神经网络的性质和灵敏度,与神经网络模型进行了比较。套袋神经网络在预测影响新生儿死亡率的因素方面具有较好的效果,准确率为99.24%。结果我们提出的方法表明,胎龄是新生儿出生时状态的最重要预测因素。此外,1分钟的Apgar、复苏需求、5分钟的Apar、出生体重、先天性畸形和出生顺序,以及母亲的糖尿病和先兆子痫,被确定为胎龄后最重要的预测因素。结论本研究发现的因素可被认为是降低新生儿死亡率的因素。这可以帮助母亲社区的健康,优化医疗服务和社会发展。
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引用次数: 0
Natural disease history and characterization of SUMF1 molecular defects in multiple sulfatase deficiency: a case report 多重硫酸酯酶缺乏症中SUMF1分子缺陷的自然发病史和特征:1例报告
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-10-05 DOI: 10.22038/IJP.2021.57775.4532
Shokoufeh Khanzadeh, Meisam Babaei, Parvin Imanpour, Shahram Sadeghvand
Multiple sulfatase deficiency (MSD) is a very rare lysosomal storage disease(LSD) caused by mutations in the SUMF1 gene. So far, about 143 patients with MSD have been reported in previous studies, although this figure is likely an underestimation due to under-reporting and under-recognition. This report showed the genetic and clinical aspects of a patient with MSD compared with previously reported patients.
多发性硫酸酯酶缺乏症(MSD)是一种非常罕见的由SUMF1基因突变引起的溶酶体贮积病(LSD)。到目前为止,在以前的研究中已经报告了大约143名默沙东患者,尽管由于报告不足和认识不足,这个数字可能被低估了。本报告显示了默沙东患者与先前报道的患者相比的遗传和临床方面。
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引用次数: 0
The effect of glucocorticoid therapy on bone mineral density in children and adolescents with congenital adrenal hyperplasia 糖皮质激素治疗对先天性肾上腺增生儿童及青少年骨密度的影响
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-09-22 DOI: 10.22038/IJP.2021.54310.4294
N. Ghaemi, A. Malek, Sade Hal Setare, Z. Shaye
Background: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive diseases caused by a deficiency in adrenal enzymes that lead to changes in cortisol and aldosterone levels. Objective: This study aimed to assess the bone mineral density of the spine and femoral head in children and adolescents aged 5 and 20 years, suffering from different types of congenital adrenal hyperplasia and treated with corticosteroids and to study the associated factors. Materials and method: We studies 44 patients, 26 girls and 18 boys, who were treated with corticosteroids with a physiological dose of 15-20 mg/m2 since infancy. A questionnaire was completed by patients and their parents admitted to the Endocrinology Clinic of Imam Reza Hospital of Mashhad. The patients' bone density was then measured, and the association with different factors, such as age, gender, height, weight, type of CAH, type and duration of receiving corticosteroids, the 17-hydroxyprogesterone level, bone activity markers, vitamin D level, and puberty stage, was analyzed, using SPSS software. Result: No significant correlation between the bone density level and variables such as the duration and dose of corticosteroid consumption, age, sex, time of diagnosis, 17-hydroxyprogesterone level, calcium, and phosphorus, was found. Other variables such as height, weight, puberty stage, and vitamin D levels were found to play a significant role in determining the bone density level.Conclusion: It is highly recommended to consider the side effects and complications when starting treatment with corticosteroids in patients with CAH. Bone densitometry should regularly be done, osteoporosis prophylaxis should be considered using weight-bearing exercises and calcium and vitamin D supplements, and the level of vitamin D should be monitored.
背景:先天性肾上腺增生症(CAH)是一组常染色体隐性遗传病,由肾上腺酶缺乏导致皮质醇和醛固酮水平改变引起。目的:本研究旨在评估5岁和20岁儿童和青少年不同类型先天性肾上腺皮质增生经皮质类固醇治疗后脊柱和股骨头的骨密度,并探讨其相关因素。材料和方法:我们研究了44例患者,其中女孩26例,男孩18例,从婴儿期开始接受糖皮质激素治疗,生理剂量为15- 20mg /m2。就诊于马什哈德伊玛目礼萨医院内分泌科诊所的患者及其父母填写了一份调查问卷。测量患者骨密度,并采用SPSS软件分析骨密度与年龄、性别、身高、体重、CAH类型、皮质类固醇使用类型及持续时间、17-羟孕酮水平、骨活性指标、维生素D水平、青春期分期等因素的关系。结果:骨密度水平与皮质类固醇使用时间、剂量、年龄、性别、诊断时间、17-羟孕酮水平、钙、磷等变量无显著相关。研究发现,身高、体重、青春期和维生素D水平等其他变量在决定骨密度水平方面也起着重要作用。结论:强烈建议在CAH患者开始使用皮质类固醇治疗时考虑其副作用和并发症。应定期进行骨密度测量,骨质疏松症预防应考虑使用负重运动和钙和维生素D补充剂,并应监测维生素D水平。
{"title":"The effect of glucocorticoid therapy on bone mineral density in children and adolescents with congenital adrenal hyperplasia","authors":"N. Ghaemi, A. Malek, Sade Hal Setare, Z. Shaye","doi":"10.22038/IJP.2021.54310.4294","DOIUrl":"https://doi.org/10.22038/IJP.2021.54310.4294","url":null,"abstract":"Background: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive diseases caused by a deficiency in adrenal enzymes that lead to changes in cortisol and aldosterone levels. \u0000\u0000Objective: This study aimed to assess the bone mineral density of the spine and femoral head in children and adolescents aged 5 and 20 years, suffering from different types of congenital adrenal hyperplasia and treated with corticosteroids and to study the associated factors. \u0000\u0000Materials and method: We studies 44 patients, 26 girls and 18 boys, who were treated with corticosteroids with a physiological dose of 15-20 mg/m2 since infancy. A questionnaire was completed by patients and their parents admitted to the Endocrinology Clinic of Imam Reza Hospital of Mashhad. The patients' bone density was then measured, and the association with different factors, such as age, gender, height, weight, type of CAH, type and duration of receiving corticosteroids, the 17-hydroxyprogesterone level, bone activity markers, vitamin D level, and puberty stage, was analyzed, using SPSS software. \u0000\u0000Result: No significant correlation between the bone density level and variables such as the duration and dose of corticosteroid consumption, age, sex, time of diagnosis, 17-hydroxyprogesterone level, calcium, and phosphorus, was found. Other variables such as height, weight, puberty stage, and vitamin D levels were found to play a significant role in determining the bone density level.\u0000\u0000Conclusion: It is highly recommended to consider the side effects and complications when starting treatment with corticosteroids in patients with CAH. Bone densitometry should regularly be done, osteoporosis prophylaxis should be considered using weight-bearing exercises and calcium and vitamin D supplements, and the level of vitamin D should be monitored.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"70 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2021-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41274980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Outcomes of Cochlear Implantation on Language Skills and Speech Intelligibility in Early-implanted versus Late-implanted Deaf Children 人工耳蜗植入对早期和晚期聋儿语言技能和言语清晰度的长期影响
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-09-21 DOI: 10.22038/IJP.2021.57919.4546
S. Hassanzadeh, M. Ajalloueyan, Azam Mirdeharbab, A. Arjmandnia, Mahdieh Hasanalifard, M. Saeedi, Alireza Aghaz
Background: Hearing loss may affect many aspects of a person's life. The age of cochlear implantation (CI) is often considered an important predictor of language skills of children with CI, but little is known about the benefits of early CI on speech intelligibility development in these children. This study aimed to compare language skills as well as intelligibility of speech in prelingual deaf patients who received CI before the age of six years and those who received CI after the age of six years with an 8-year follow-up.Materials and Methods: This 8-year longitudinal, retrospective case–control study was conducted in 2021 at a cochlear implant center in Tehran, Iran. Thirty-one patients were included in two groups: late cochlear implant (n = 15), and early cochlear implant (n =16). The Test of Language Development- Primary (TOLD-P3) was used to assess the participants 'language skills. The intelligibility of the participants' speech was assessed through the Persian version of the Intelligibility Context Scale (ICS) and the speech intelligibility rating (SIR).Results: These two groups did not show a significantly difference in terms of the language scores (P>0.05) but had a significantly difference in terms of the SIR and the ICS scores (P<0.05). Speech intelligibility had a significantly negative correlation with the age of CI (P<0.001), and had a significant positive correlation with language skills (P<0.001).Conclusion: The long-term outcomes of early and late CI were similar in terms of the development of language skills but too different in terms of the intelligibility of speech. The age of CI had no effect on the language development but had a significant effect on speech intelligibility.
背景:听力损失可能影响一个人生活的许多方面。人工耳蜗植入(CI)的年龄通常被认为是CI儿童语言技能的重要预测因素,但对早期CI对这些儿童语音清晰度发展的益处知之甚少。这项研究旨在比较在6岁之前接受CI的语前聋人患者和在6岁之后接受CI并进行8年随访的语前聋哑患者的语言技能和言语清晰度。材料和方法:这项为期8年的纵向回顾性病例对照研究于2021年在伊朗德黑兰的耳蜗植入中心进行。31名患者分为两组:晚期人工耳蜗植入术(n=15)和早期人工耳蜗植入手术(n=16)。初级语言发展测试(TOLD-P3)用于评估参与者的语言技能。通过波斯语版的可懂度上下文量表(ICS)和语音可懂度评分(SIR)评估参与者的语音可懂程度。结果:这两组在语言得分方面没有显著差异(P>0.05),但在SIR和ICS得分方面有显著差异(P<0.05)与CI年龄呈显著负相关(P<0.001),与语言技能呈显著正相关(P>0.001)。结论:早期和晚期CI在语言技能发展方面的长期结果相似,但在言语清晰度方面差异太大。CI的年龄对语言发展没有影响,但对语音清晰度有显著影响。
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引用次数: 0
Association Passive Smoking with Dental Caries and Cotinine Biomarker among 8-12 Years Old Children of Semnan, Iran 伊朗塞姆南8-12岁儿童被动吸烟与龋齿和可替宁生物标志物的关系
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-09-21 DOI: 10.22038/IJP.2021.59254.4615
Shabnam Sohanian, R. Ghorbani, O. Mirmohammadkhani, Homa Delavari, Kamyar Mansori
Background: The present study was designed to determine association passive smoking with dental caries and cotinine biomarker among 8-12 years old children of Semnan, Iran. Materials and Methods: This cross sectional study was concocted on two groups of 8-12 years old children exposed (n=100) and non-exposed to passive smoking (n=100) in of Semnan (Iran). The sampling method was two-stage cluster sampling design. The data collection tool a standard checklist consisted of demographic, laboratory and dental characteristics. Examination was performed by a dentist on a dental unit and the dental indicators were measured for two groups. Also, salivary cotinine was measured and recorded using ELISA method by special cotinine kit (De salimetrics medi tec, USA). Univariate and Multivariable Logistic Regression model and area under the ROC curve were used to data analysis by STATA 14 software. Results: Univariate logistic regression model showed a statistically significant difference between the exposed and unexposed groups with passive smoking in term of the salivary cotinine level, age , sex , decayed, missing, and filled teeth (dmft) index, decayed, and filled teeth (dft) index and missing teeth (mt) (P-Value ≤0.20). However, multiple logistic regression model showed a statistically significant relationship between the decayed, missing, and filled teeth (dmft) index and passive smoking (OR=1.28; 95% CI: 1.05 – 1.38). Conclusion: This study showed that the risk of decay of deciduous teeth is higher in children exposed to passive smoking, therefore, passive smoking should be considered in the implementation of programs to prevent tooth decay in children.
背景:本研究旨在确定伊朗Semnan 8-12岁儿童被动吸烟与龋齿和可替宁生物标志物的关系。材料与方法:本横断面研究采用伊朗塞姆南(Semnan) 8-12岁被动吸烟暴露儿童(n=100)和非被动吸烟暴露儿童(n=100)两组进行。抽样方法为两阶段整群抽样设计。数据收集工具为标准检查表,包括人口统计学、实验室和牙科特征。由一名牙医在牙科单位进行检查,并测量两组的牙科指标。使用特制的可替宁检测试剂盒(De salimetrics medi tec, USA),采用ELISA法测定唾液可替宁。采用STATA 14软件对数据进行分析,采用单变量和多变量Logistic回归模型及ROC曲线下面积。结果:单因素logistic回归模型显示,被动吸烟暴露组与未暴露组在唾液可替宁水平、年龄、性别、龋缺补牙(dmft)指数、龋缺补牙(dft)指数、缺牙(mt)方面差异均有统计学意义(p值≤0.20)。然而,多元logistic回归模型显示,龋缺补指数与被动吸烟之间存在统计学意义(OR=1.28;95% ci: 1.05 - 1.38)。结论:本研究表明被动吸烟儿童乳牙发生龋齿的风险较高,因此在实施预防儿童龋齿的方案时应考虑被动吸烟。
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引用次数: 0
Evaluation of the Ventricular Function based on Echocardiographic Findings in Asthmatic Children Referred to Rasoul Akram and Firoozabadi Hospitals of Tehran 根据超声心动图结果评估转诊至德黑兰Rasoul Akram和Firoozabadi医院的哮喘儿童的心室功能
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-09-21 DOI: 10.22038/IJP.2021.59039.4602
M. Fallahpour, M. Radgoudarzi, Mojtaba Didar Shetaban, Mohammad Bagher Didarshetaban
Objective: Asthma is a chronic inflammatory disease of the lead to hypertrophy and dilatation of the right ventricle. Aim of study to evaluate and compare left and right ventricular systolic and diastolic function of the heart based on echocardiographic criteria in children with moderate to severe asthma and non-asthmatic children referred to Hazrat Rasouland Firoozabadi Hospitals of Tehranin 2019. Methods: In this case-control study, 50 patients with a definite diagnosis of moderate to severe asthma(case group) and 50 healthy individuals (control group) were studied and compared in terms of clinical and echocardiographic measures. Blood pressure, heart rate, body height and weight of all children were recorded. The patients who were >6 years underwent pulmonary function tests using spirometry. Conventional and TDI echocardiography was performed bya single experienced pediatric cardiologist on two groups blindly and echocardiographic data was collected.Results: The results showed that the left ventricular stroke volume was significantly lower in patients with asthma. Also, in the right ventricular SV, significantly lower values were found in the group of patients under study than healthy individuals (P=0.01). The E/A ratio in both groups was higher than one with a mean and standard deviation of 1.72±0.26 in the case group compared to 1.92±0.32 which was not significantly different.Conclusion: The results of this study showed that asthma can affect ventricular contraction in children. Contrary to previous studies and despite the observation of cardiac systolic dysfunction in patients with asthma, diastolic dysfunction in these patients was not observed even by tissue Doppler echocardiography.Keywords: Asthma, Cardiac function, Echocardiography
目的:哮喘是一种导致右心室肥大和扩张的慢性炎症性疾病。目的评价和比较2019年德黑兰Hazrat Rasouland Firoozabadi医院中重度哮喘患儿和非哮喘患儿的心脏左、右心室收缩和舒张功能。方法:对50例确诊为中重度哮喘的患者(病例组)和50例健康人群(对照组)进行临床及超声心动图指标的比较研究。记录所有儿童的血压、心率、身高和体重。年龄60 ~ 60岁的患者采用肺量测定法进行肺功能检查。由一名经验丰富的儿科心脏病专家对两组进行常规和TDI超声心动图检查,并收集超声心动图数据。结果:哮喘患者左室全搏容量明显降低。此外,在右心室SV中,研究组患者的值明显低于健康人(P=0.01)。两组的E/A比均高于1组,病例组的平均值和标准差分别为1.72±0.26和1.92±0.32,差异无统计学意义。结论:哮喘可影响儿童心室收缩。与以往的研究相反,尽管在哮喘患者中观察到心脏收缩功能障碍,但即使通过组织多普勒超声心动图也未观察到这些患者的舒张功能障碍。关键词:哮喘,心功能,超声心动图
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引用次数: 0
The Efficiency of Epiphysiodesis for Growth Modulation in Patients with Congenital Scoliosis: A Systematic Review 体表成形术对先天性脊柱侧凸患者生长调节的效果:一项系统综述
IF 2.1 Q3 PEDIATRICS Pub Date : 2021-09-12 DOI: 10.22038/IJP.2021.56414.4434
E. Keykhosravi, H. Rezaee, Amin Tavallaii, Mohammad Abouei Mehrizi, A. Pourbagher-Shahri, Vahid Khajereza Shahri, Ahmad Abdul Sater Abdul Sater
Purpose: Congenital scoliosis (CS) is a challenging entity in spinal surgery. Convex growth arrest (CGA) is a therapeutic method aiming at inhibiting growth on the curve convexity while remained growth of concavity corrects the scoliotic curve over time. In the view of controversies in current clinical studies for efficiency of CGA in CS patients, we performed a systematic review of the literature to clarify the debate. Methods: A comprehensive literature search was performed to identify studies assessing CGA outcome in CS patients, in following databases and search engines: Ovid MEDLINE, PubMed, Scopus, Cochrane Central Register of Controlled Trials (CCTR), EMBASE, Google Scholar, and Web of Science. Two authors screened the search results and selected the studies by the supervision of senior authors.Results: In 19 studies, enrolling 363 patients, age at surgery was 58.76 months ranging from 4 to 216 months. Anterior and posterior hemiepiphysiodesis was the most common approach. Eight studies added instrumentation to CGA. Follow-up mean was 64.57 months. Nine studies reported true epiphysiodesis effect (postoperative and final follow-up CCA difference): of 162 patients, 69 improved, 59 stabilized, and 34 progressed. Other studies reported preoperative and final follow-up CCA difference: of 88 patients, 49 improved, 32 stabilized, and 7 progressed. Preoperative curve magnitude, sagittal plane deformities, age <5 years, and type of spinal anomalies did not affect CGA outcome. Instrumentation was preferred in complicated spinal anomalies and older ages.Conclusion: CGA alone or with instrumentation is a feasible CS treatment, however criteria for choosing suitable candidates need reconsideration.
目的:先天性脊柱侧凸(CS)是脊柱外科的一个难题。凸生长抑制(CGA)是一种治疗方法,旨在抑制曲线的凸生长,而保留的凹生长随着时间的推移纠正脊柱侧凸曲线。鉴于目前临床研究中对CS患者CGA有效性的争议,我们对文献进行了系统的回顾,以澄清争论。方法:在以下数据库和搜索引擎中进行全面的文献检索,以确定评估CS患者CGA结局的研究:Ovid MEDLINE, PubMed, Scopus, Cochrane Central Register of Controlled Trials (CCTR), EMBASE,谷歌Scholar和Web of Science。两位作者对检索结果进行筛选,并在资深作者的指导下选择研究。结果:19项研究,纳入363例患者,手术年龄为58.76个月,4 ~ 216个月不等。前后半表皮成形术是最常见的入路。8项研究在CGA中添加了仪器。平均随访64.57个月。9项研究报告了真正的表皮病变效果(术后和最终随访CCA差异):162例患者中,69例改善,59例稳定,34例进展。其他研究报告了术前和最终随访的CCA差异:88例患者中,49例改善,32例稳定,7例进展。术前曲线大小、矢状面畸形、年龄<5岁和脊柱异常类型对CGA结果没有影响。在复杂的脊柱异常和老年人中首选内固定。结论:CGA单独或联合内固定是可行的CS治疗方法,但选择合适的标准需要重新考虑。
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International Journal of Pediatrics
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