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Advancements and Future Outlook of PET/CT-Guided Interventions PET/ ct引导介入治疗的进展与展望
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-09-01 DOI: 10.1016/j.tvir.2023.100916
Omar Dzaye MD, MPH, PhD , Francois H. Cornelis MD, PhD , Henry S. Kunin BS , Constantinos T. Sofocleous MD, PhD

Advancements in minimally invasive technology, coupled with imaging breakthroughs, have empowered the field of interventional radiology to achieve unparalleled precision in image-guided diagnosis and treatment while simultaneously reducing periprocedural morbidity. Molecular imaging, which provides valuable physiological and metabolic information alongside anatomical localization, can expand the capabilities of image-guided interventions. Among various molecular imaging techniques, positron emission tomography (PET) stands out for its superior spatial resolution and ability to acquire quantitative data. PET has emerged as a crucial tool for oncologic imaging and plays a pivotal role in both staging and the assessment of treatment responses. Typically used in combination with computed tomography (CT) (PET/CT) and occasionally with magnetic resonance imaging MRI (PET/MRI), PET as a hybrid imaging approach offers enhanced insights into disease progression and response. In recent years, PET has also found its way into image-guided interventions, especially within the rapidly expanding field of interventional oncology. This review aims to explore the current and evolving role of metabolic imaging, specifically PET, in interventional oncology. By delving into the unique advantages and applications of PET in guiding oncological interventions and assessing response, we seek to highlight the increasing significance of this modality in the realm of interventional radiology.

微创技术的进步,加上成像技术的突破,使介入放射学领域在图像引导诊断和治疗方面达到了无与伦比的精确度,同时减少了手术期间的发病率。分子成像可以提供有价值的生理和代谢信息以及解剖定位,可以扩展图像引导干预的能力。在各种分子成像技术中,正电子发射断层扫描(PET)以其优越的空间分辨率和获得定量数据的能力而脱颖而出。PET已成为肿瘤成像的重要工具,在分期和治疗反应评估中起着关键作用。通常与计算机断层扫描(CT) (PET/CT)结合使用,偶尔与磁共振成像MRI (PET/MRI)结合使用,PET作为一种混合成像方法,可以增强对疾病进展和反应的了解。近年来,PET也在图像引导干预中找到了自己的方式,特别是在快速扩张的介入肿瘤学领域。本综述旨在探讨代谢成像,特别是PET在介入肿瘤学中的作用。通过深入研究PET在指导肿瘤干预和评估反应方面的独特优势和应用,我们试图强调这种模式在介入放射学领域日益增长的重要性。
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引用次数: 0
Image Fusion Technology in Interventional Radiology 介入放射学中的图像融合技术
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-09-01 DOI: 10.1016/j.tvir.2023.100915
Monzer Chehab MD , Brian E. Kouri MD , Michael J. Miller MD , Aradhana M. Venkatesan MD

Image fusion technology aims to improve patient outcomes for image-guided interventions by leveraging the strengths of multimodality imaging datasets. This most commonly involves the overlay or co-display of advanced cross-sectional imaging permitting freedom of device placement via conventional image guidance such as ultrasound, fluoroscopy, and computed tomography. This can allow the interventionalist to target and treat lesions that would otherwise be difficult or impossible to visualize and access using conventional imaging guidance. Furthermore, the use of image fusion can allow for procedures traditionally performed with cross-sectional imaging to be performed under ultrasound or fluoroscopy, by importing the data from preacquired cross-sectional imaging into the interventional procedure. This manuscript provides an overview of image fusion technologies used for interventional radiology (IR) guidance, with an emphasis on technical considerations.

图像融合技术旨在通过利用多模态成像数据集的优势,改善图像引导干预的患者结果。这最常见的包括覆盖或共同显示先进的横断面成像,允许通过常规图像引导(如超声、透视和计算机断层扫描)自由放置设备。这使得介入医师能够瞄准和治疗病变,否则使用传统成像引导很难或不可能可视化和接近病变。此外,通过将预先获得的横断面成像数据输入到介入手术中,图像融合的使用可以允许传统的横断面成像手术在超声或透视下进行。本文概述了用于介入放射学(IR)指导的图像融合技术,重点是技术方面的考虑。
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引用次数: 0
Expanding the Horizons of Interventional Radiology With Advanced Image Guidance and Robotics 利用先进的图像引导和机器人技术拓展介入放射学的视野
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-09-01 DOI: 10.1016/j.tvir.2023.100910
Francois H. Cornelis MD, PhD , Stephen B. Solomon MD , Muneeb Ahmed MD
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引用次数: 0
Catheter Directed Thrombectomy and Other Deep Venous Interventions in Cancer Patients 癌症患者的导管引导血栓切除术和其他深静脉介入治疗。
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-06-01 DOI: 10.1016/j.tvir.2023.100900
Mari Tanaka MD , Rui Dai MD, PhD , Animan Randhawa MD , Sara Smolinski-Zhao MD , Vincent Wu MD , T. Gregory Walker MD , Dania Daye MD, PhD

Treating cancer patients with deep venous thrombosis/venous thromboembolism (DVT/VTE) can be challenging as patients are frequently unable to receive the standard therapy of anticoagulation due to the increased risk of bleeding complications seen in this population. Similarly, the hesitation of interventionalists to use thrombolytic agents due to bleeding risks limits percutaneous intervention options as well. Further, outcome data and guidelines do not exist for oncologic patients and often treatment is tailored to patient-specific factors after multidisciplinary discussion. This article reviews specific factors to consider when planning percutaneous treatment of cancer patients with DVT/VTE, focusing on the iliocaval system.

治疗患有深静脉血栓形成/静脉血栓栓塞症(DVT/VTE)的癌症患者可能具有挑战性,因为患者通常无法接受标准的抗凝治疗,因为这一人群中出血并发症的风险增加。同样,由于出血风险,介入治疗者对使用溶栓药物的犹豫也限制了经皮介入治疗的选择。此外,肿瘤学患者的结果数据和指南并不存在,通常在多学科讨论后根据患者的具体因素进行治疗。本文综述了在计划经皮治疗癌症DVT/VTE患者时应考虑的具体因素,重点是髂腔系统。
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引用次数: 1
How to Evaluate and Choose the Proper Treatments for Patients with Lower Extremity Venous Disease 如何评估和选择合适的治疗方法治疗下肢静脉疾病。
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-06-01 DOI: 10.1016/j.tvir.2023.100895
Suman M. Wasan MD, MS

With an increasing number of interventional and noninterventional treatment options available for venous disorders, it is important that patients undergo a thorough and systematic evaluation. Clinical evaluation should include a personal and family history of venous thromboembolism (VTE), varicose veins, and thrombophilia as these factors affect response and recurrence of disease. Patient should undergo diagnostic and quality of life assessment using validated tools to monitor response to treatment. Duplex ultrasound, both deep and superficial veins, documenting both obstruction and reflux is initial imaging with CT and MRI indicated to document pelvic, iliac vein, and IVC patency and pathology. Conservative therapy including compression, healthy lifestyle with diet, and exercise. New and novel interventional therapies are available for patients with venous disease with recent randomized controlled trials and multisocietal guidelines providing evidence-based recommendations for patients with superficial and deep venous disease. Since the use of anticoagulant and antiplatelet therapies post venous intervention is not well studied nor standardized, patients should routinely undergo evaluation for ongoing risk of recurrent thrombosis and stent occlusion. Finally, patients should be counseled that superficial and deep venous disease is a chronic and often progressive disease, and follow-up at least annually is recommended.

随着静脉疾病的介入和非介入治疗选择越来越多,对患者进行彻底和系统的评估很重要。临床评估应包括静脉血栓栓塞症(VTE)、静脉曲张和血栓形成倾向的个人和家族史,因为这些因素会影响疾病的反应和复发。患者应使用经验证的工具进行诊断和生活质量评估,以监测对治疗的反应。双相超声,包括深静脉和浅静脉,记录梗阻和反流是CT和MRI的初步成像,用于记录盆腔、髂静脉和IVC的通畅性和病理学。保守疗法包括压迫、健康的饮食生活方式和锻炼。新的和新颖的介入疗法可用于静脉疾病患者,最近的随机对照试验和多社会指南为浅静脉和深静脉疾病患者提供了循证建议。由于静脉介入治疗后抗凝和抗血小板治疗的使用没有得到很好的研究,也没有标准化,患者应该定期接受复发性血栓形成和支架闭塞的持续风险评估。最后,应告知患者浅静脉和深静脉疾病是一种慢性且经常进行性疾病,建议至少每年随访一次。
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引用次数: 0
Lessons Learned With Venous Stenting: In-flow, Outflow, and Beyond 静脉支架的经验教训:流入、流出和超越。
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-06-01 DOI: 10.1016/j.tvir.2023.100897
George Rahmani FFR (RCSI), Gerard J. O'Sullivan FRCR, FRCPI, F-CIRSE, F-SIR

Venous stents are being used with increasing frequency, with a multitude of dedicated venous stents now well established or emerging onto the market. This review explores the multifaceted aspects of venous stenting. We discuss the history of venous stents, indications for their use, the imaging required before, during and after stenting, as well as some technical tips and tricks which we have found to be helpful in our own daily practice with a particular focus on iliofemoral venous stenting. Ultimately, this article seeks to enhance the understanding of venous stenting, offering insights into what we feel are best practices, challenges, and prospects for improved patient outcomes.

静脉支架的使用频率越来越高,许多专用静脉支架现在已经成熟或正在市场上出现。这篇综述探讨了静脉支架术的多方面。我们讨论了静脉支架的历史、使用适应症、支架植入前、植入中和植入后所需的成像,以及一些我们发现在日常实践中有帮助的技术技巧和窍门,特别关注髂股静脉支架植入。最终,本文旨在增强对静脉支架术的理解,深入了解我们认为的最佳实践、挑战和改善患者预后的前景。
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引用次数: 0
Back To Basics: Theory of Thrombus Formation and Potential Implications for Therapies? 回归基础:血栓形成理论及其对治疗的潜在意义?
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-06-01 DOI: 10.1016/j.tvir.2023.100894
M. Silena Mosquera MD , Jose A. Diaz MD, FAHA

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common and potentially fatal condition. Despite existing treatments, recurrence rates and complications remain high. Understanding the pathophysiology of thrombus formation is crucial for developing effective therapies. This narrative review provides an overview of the critical elements of acute and chronic DVT, presents a theoretical framework for understanding thrombus formation, and discusses potential implications for therapeutic interventions. In addition, a hypothesis of thrombus formation is formulated, encompassing all elements described in this work.

静脉血栓栓塞(VTE),包括深静脉血栓形成(DVT)和肺栓塞(PE),是一种常见且可能致命的疾病。尽管有现有的治疗方法,复发率和并发症仍然很高。了解血栓形成的病理生理学对于开发有效的治疗方法至关重要。这篇叙述性综述概述了急性和慢性DVT的关键因素,提出了理解血栓形成的理论框架,并讨论了治疗干预的潜在意义。此外,还提出了血栓形成的假设,包括本工作中描述的所有元素。
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引用次数: 0
Venous Thromboembolism Management in Pregnant Patients 妊娠患者的静脉血栓栓塞治疗。
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-06-01 DOI: 10.1016/j.tvir.2023.100901
Linzi A. Webster MD, Vivian Bishay MD

Pulmonary embolism (PE) in pregnancy accounts for 10% of maternal deaths in the United States. As maternal morbidity and mortality continue to increase, it is imperative for all specialties interfacing with pregnant patients to understand the current research and guidelines surrounding risk stratification, diagnosis, and treatments of PE in pregnancy. Given the complexity of high-risk pregnancy-associated PE (PA-PE), that is, which is associated with hemodynamic instability or collapse, and the rising popularity of new technologies to treat high-risk PA-PE in the nonpregnant population, this review aims to emphasize the differences in diagnosis, risk stratification, and management of the pregnant and nonpregnant PE patients. Furthermore, this review will cover treatment paradigms that include anticoagulation versus advanced therapies such as systemic thrombolysis, surgical embolectomy, extracorporeal membrane oxygenation, and inferior vena cava disruption as well as the more novel therapies which fall under the umbrella term of catheter-based treatments. Finally, this review will include a case-based review of 2 patients with PA-PE requiring catheter-based therapies and their ultimate clinical outcomes.

在美国,妊娠期肺栓塞(PE)占孕产妇死亡的10%。随着孕产妇发病率和死亡率的持续增加,与孕妇患者接触的所有专业都必须了解当前围绕妊娠期PE风险分层、诊断和治疗的研究和指南。鉴于高危妊娠相关PE(PA-PE)的复杂性,即与血液动力学不稳定或衰竭相关,以及治疗高危PA-PE的新技术在非妊娠人群中越来越流行,本综述旨在强调妊娠和非妊娠PE患者在诊断、风险分层和管理方面的差异。此外,这篇综述将涵盖抗凝治疗与先进治疗的治疗模式,如全身溶栓、手术栓塞切除术、体外膜肺氧合和下腔静脉破裂,以及导管治疗的新疗法。最后,本综述将包括对2名需要导管治疗的PA-PE患者及其最终临床结果的基于病例的综述。
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引用次数: 0
Combined Management of Wound Ulcers With Focus on Interventional Techniques 以介入技术为重点的伤口溃疡联合治疗。
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-06-01 DOI: 10.1016/j.tvir.2023.100896
Teodora Bochnakova MD, Claire Kaufman MD

This review provides a summary of current practice patterns in managing venous ulcers. The authors will describe the workup for venous ulcers, including differentiation of symptoms, physical examination, and imaging to guide the most effective treatment course for each patient. An overview of conservative management and minimally invasive treatment options for venous ulcers will be provided with a specific focus on periulcer foam sclerotherapy to aid in preventing ulcer recurrence and promoting healing. We will give interventional troubleshooting techniques for challenging patient presentations.

这篇综述提供了当前静脉溃疡管理实践模式的总结。作者将描述静脉溃疡的治疗方法,包括症状的鉴别、身体检查和影像学检查,以指导每位患者最有效的治疗方案。将提供静脉性溃疡的保守治疗和微创治疗方案的概述,特别关注溃疡周围泡沫硬化治疗,以帮助预防溃疡复发和促进愈合。我们将为具有挑战性的患者介绍提供介入性故障排除技术。
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引用次数: 0
Multidisciplinary Approach to Venous Disease: Enhancing Patient Care and Trainee Education Through Collaboration 静脉疾病的多学科方法:通过合作加强患者护理和受训人员教育。
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-06-01 DOI: 10.1016/j.tvir.2023.100902
Mario Dervishi MD , Mohamed Al-Natour MD , Jones P. Thomas MD , Karem Harth MD, MHS

The full spectrum of venous disease poses a significant burden on individuals and health-care systems globally. Venous disease can lead to a wide range of symptoms based on the level of disease and underlying pathology. In general, underlying pathologies are due to nonthrombotic (reflux/obstructive) and thrombotic causes. Most conditions are a sequela of the long-term effects of chronic venous insufficiency, deep vein thrombosis (DVT), or nonthrombotic deep vein obstruction. The prevalence of venous disease is substantial, impacting the quality of life of a considerable proportion of the adult population. Untreated and progressive lower extremity venous disease can lead to venous ulceration and other complications. Additionally, poorly recognized and poorly understood venous conditions of the abdomen and pelvis leave many patients “orphaned” in health-care systems that lack expertise in complex venous conditions. Addressing the burden and breadth of venous disease requires comprehensive management approaches, early diagnosis, appropriate treatment interventions, and provider and patient education. Multidisciplinary collaborations and further research are essential to enhance our understanding, develop innovative therapies, and improve patient outcomes in the field of venous disease. In this paper, we highlight the importance of multidisciplinary collaboration and our journey to building an institutional venous team, as well as lessons learned.

全方位的静脉疾病给全球个人和医疗保健系统带来了巨大负担。根据疾病的程度和潜在的病理学,静脉疾病可以导致广泛的症状。一般来说,潜在的病理是由非血栓(反流/阻塞性)和血栓形成的原因引起的。大多数情况是慢性静脉功能不全、深静脉血栓形成(DVT)或非血栓性深静脉阻塞的长期影响的后遗症。静脉疾病的患病率很高,影响了相当一部分成年人口的生活质量。未经治疗和进行性下肢静脉疾病可导致静脉溃疡和其他并发症。此外,人们对腹部和骨盆的静脉状况认识不足和了解不足,使许多患者在缺乏复杂静脉状况专业知识的医疗系统中成为“孤儿”。解决静脉疾病的负担和广度需要综合管理方法、早期诊断、适当的治疗干预以及提供者和患者教育。多学科合作和进一步研究对于增强我们在静脉疾病领域的理解、开发创新疗法和改善患者预后至关重要。在本文中,我们强调了多学科合作的重要性、我们建立机构静脉团队的历程以及经验教训。
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引用次数: 0
期刊
Techniques in Vascular and Interventional Radiology
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