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Contrasting pediatric specialty provider opinion between contextualized and structured radiology reports 对比儿科专业医疗人员对情境化和结构化放射学报告的意见。
IF 1.5 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-03 DOI: 10.1067/j.cpradiol.2024.05.004

Background

Structured reporting (SR) replaced narrative (free text) reporting and utilizes templated headings and subheadings with findings typically based on the anatomy included in the examination. Its use has been widely advocated by radiology and non-radiology organizations as the new reporting standard. There are, however, shortcomings to SR, such as templated text not addressing a specific clinical indication. Contextual reporting (CR) fills this gap. CR is a type of SR which is tailored to a narrow clinical indication by including pertinent positive and negative findings for that specific clinical entity.

Objective

This study assesses provider preferences for CR as compared to SR in the pediatric practice environment using a survey methodology.

Methods & materials

Surveys with examples of SR and CR reports were sent electronically to two groups. One group was focused on neurological diseases and included pediatric specialists in neurosurgery, neurology, ENT, ED, and ophthalmology (190 people), referred to as the pediatric neuroimaging group. The pediatric neuroimaging group survey contained examples of CR and SR reports of an orbital CT for orbital cellulitis and a head CT for stroke. The other group was focused on gastrointestinal diseases, and included pediatric specialists in gastroenterology, general surgery, and the ED (159 people), referred to as the pediatric gastrointestinal (GI) imaging group. The pediatric GI imaging group survey contained example reports of an abdominal CT for appendicitis and an MRI enterography for Crohn's disease. Surveys utilizing a 5-point Likert scale were analyzed via Fischer's exact test with a p-value deemed statistically significant at less than 0.05.

Results

349 individuals were contacted to participate in the survey. There were 81 (23 %, 81/349) survey respondents; 41 (22 %, 41/190) from the neuro group, and 40 (25 %, 40/159) from the GI group. 56 % (45/81) of all respondents preferred CR reports over traditional SR reports, while 29 % (23/81) did not. Most respondents (59 %, 48/81) indicated that CR reports are easier to interpret than traditional SR reports. Respondents from the pediatric neuroimaging group favored CR reports to a lesser degree (44 %, 36/81) compared to respondents from the pediatric GI imaging group (68 %, 55/81).

Conclusions

We learned from this survey that it would be beneficial to be very intentional about selecting clinical indications where CR would be most valued rather than trying to develop CR for any specific clinical indication. The study results indicate it is reasonable to continue further efforts at exploring the utility of contextualized reports.

背景:结构化报告(SR)取代了叙述式(自由文本)报告,采用模板化的标题和副标题,其结果通常基于检查中包含的解剖结构。放射科和非放射科组织广泛提倡将其作为新的报告标准。然而,SR 也有不足之处,例如模板化的文本并不针对特定的临床指征。上下文报告(Contextual Report,CR)填补了这一空白。情境报告是一种针对特定临床适应症的 SR,它包括针对特定临床实体的相关阳性和阴性结果:本研究采用调查方法,评估儿科实践环境中医疗服务提供者对 CR 与 SR 的偏好:通过电子方式向两组医疗服务提供者发送附有 SR 和 CR 报告实例的调查问卷。一组侧重于神经系统疾病,包括神经外科、神经内科、耳鼻喉科、急诊科和眼科的儿科专家(190 人),称为儿科神经影像组。小儿神经影像组的调查包含了眼眶蜂窝组织炎的眼眶 CT 和中风的头部 CT 的 CR 和 SR 报告实例。另一组主要研究胃肠道疾病,包括消化内科、普外科和急诊室的儿科专家(159 人),称为儿科胃肠道(GI)成像组。儿科胃肠成像组调查包含阑尾炎腹部 CT 和克罗恩病 MRI 肠造影的实例报告。调查采用 5 点李克特量表,通过费舍尔精确检验进行分析,P 值小于 0.05 即具有统计学意义:共联系了 349 人参与调查。共有 81 人(23%,81/349)参与调查,其中 41 人(22%,41/190)来自神经组,40 人(25%,40/159)来自消化道组。与传统的 SR 报告相比,56% 的受访者(45/81)更喜欢 CR 报告,29% 的受访者(23/81)不喜欢 CR 报告。大多数受访者(59%,48/81)表示 CR 报告比传统 SR 报告更容易解读。与小儿消化道成像组的受访者(68%,55/81)相比,小儿神经成像组的受访者对 CR 报告的青睐程度较低(44%,36/81):我们从这次调查中了解到,有意识地选择 CR 最有价值的临床适应症,而不是试图为任何特定的临床适应症开发 CR,将是有益的。研究结果表明,继续进一步努力探索情境化报告的实用性是合理的。
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引用次数: 0
The clinical year dilemma: Examining the stressors and alternatives of pre-radiology training 临床年的困境:研究放射学预科培训的压力和替代方案。
IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-03 DOI: 10.1067/j.cpradiol.2024.05.009
Thomas Stirrat BS , Robert Martin DO , Joseph Waller MD , Arvind Dev BS , Muhammad Umair MD

Since its reinstatement in 1997, the effectiveness of the clinical year prior to radiology residency has been a contentious topic concerning its role in cultivating skilled radiologists. This review evaluates the limitations of the one-year internship and explores alternative approaches. Utilizing databases such as PubMed, Google Scholar, and Scopus, this study identified pertinent articles that aligned with the inclusion criteria for post-graduate year 1 (PGY-1) training before radiology residency. Through a qualitative analysis of the literature, the review identifies prevalent themes concerning the drawbacks of the preliminary clinical year and potential alternative strategies.

Many current trainees express skepticism about the value of the clinical year, noting a disconnect between its generalist nature and the specialized demands of subsequent radiology training. Interns felt uncertain about radiology exam indications and found radiology departments to be unapproachable, reflecting the need for alternative educational strategies to improve the preparedness and confidence of radiology interns as they transition from academic environments to clinical practice.

The preparatory clinical year prior to entering radiology residency presents a mix of utility, along with alternative approaches to structuring this year. These alternatives include incorporating it into the undergraduate medical curriculum, restructuring or designing radiology-focused clinical years, and reevaluating the overall effectiveness of the clinical year in training.

自 1997 年恢复放射科住院医生实习前一年的临床实习以来,其在培养熟练的放射科医生方面的作用一直是一个有争议的话题。本综述评估了一年实习期的局限性,并探讨了替代方法。本研究利用 PubMed、Google Scholar 和 Scopus 等数据库,确定了符合放射科住院医生实习前研究生一年级(PGY-1)培训纳入标准的相关文章。通过对文献的定性分析,本综述确定了有关临床预备年弊端和潜在替代策略的普遍主题。许多在校实习生对临床年的价值表示怀疑,认为其通才性质与后续放射学培训的专业要求脱节。实习生对放射学考试的适应症感到不确定,并认为放射科难以接近,这反映出在放射学实习生从学术环境过渡到临床实践的过程中,需要采取其他教育策略来提高他们的准备程度和信心。放射科实习生进入临床实习前的预备临床年有多种用途,也有其他方法来安排这一年。这些替代方法包括将其纳入医学本科课程、重组或设计以放射学为重点的临床年,以及重新评估临床年在培训中的整体效果。
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引用次数: 0
Impact of the use of active methodology on the performance of undergraduate radiology students 使用主动方法对放射学本科生成绩的影响。
IF 1.5 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-03 DOI: 10.1067/j.cpradiol.2024.05.008

Rationale and objectives

Although PBL is widely used in several countries, especially in medicine courses, its application in teaching other higher education courses, which involve fundamentals applied to radiology, is still little explored. Therefore, we aim to evaluate the implementation of Problem-Based Learning (PBL) in a higher education institution's radiology and biomedicine technologist course, focusing on specific radiology-related disciplines.

Materials and methods

An interventional study was developed with 78 students. An active methodology model was created and implemented for one of the groups of participants. At the beginning of each semester, students of both groups were evaluated with pre-tests. At the end of the semesters, the students performed a post-test and a validated evaluation of the discipline methodology. Repeated measures generalized linear regressive models with robust error estimators were used to evaluate test outcomes.

Results

A significant interaction among the methodologies was found (p=0.020), with better results from students exposed to the active methodology (initial and final grades were 7.18 and 7.57 in the active methodology, respectively, and 7.45 and 6.89 in the traditional methodology, respectively). In addition, students' evaluation regarding the quality of the methodology was favorable to the active methodology with statistical significance (p<0.05) in 16 of the 22 items evaluated.

Conclusions

The students' positive response and performance were attributed to the interaction and innovation of the methodology compared to conventional methods, highlighting the effectiveness of PBL in higher education in radiology and its potential for more participatory and contextualized learning.

理由和目标:尽管问题导向学习(PBL)在多个国家得到广泛应用,尤其是在医学课程中,但在涉及放射学基础知识的其他高等教育课程教学中的应用仍鲜有探索。因此,我们旨在评估基于问题的学习(PBL)在高等教育机构放射学和生物医学技师课程中的实施情况,重点是与放射学相关的具体学科:对 78 名学生进行了干预性研究。为其中一组参与者创建并实施了一种积极的方法模式。在每个学期开始时,对两组学生进行预测试评估。学期结束时,学生们进行了后测,并对学科方法进行了有效评估。采用了带有稳健误差估计器的重复测量广义线性回归模型来评估测试结果:结果发现,不同教学方法之间存在明显的交互作用(p=0.020),采用主动教学法的学生成绩更好(主动教学法的初始成绩和最终成绩分别为 7.18 分和 7.57 分,传统教学法的初始成绩和最终成绩分别为 7.45 分和 6.89 分)。此外,学生对教学法质量的评价也有利于主动式教学法,且具有统计学意义(p 结论:与传统方法相比,学生的积极反应和表现归功于该方法的互动性和创新性,凸显了 PBL 在放射学高等教育中的有效性,以及其在更具参与性和情境化学习方面的潜力。
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引用次数: 0
Female and underrepresented minority representation in radiology 放射科中女性和代表性不足的少数族裔的代表性。
IF 1.5 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-03 DOI: 10.1067/j.cpradiol.2024.05.002

Rational and objective

Diversity, equity, inclusion, and representation in various sectors have garnered increasing attention in the past two decades, including healthcare. In this report we investigate representation of females and underrepresented minorities (URM) in the field of radiology and asses for significant growth trends in representation in residency training programs in the United States.

Materials and methods

De-identified trainee demographic information for active radiology trainees from 2016 to 2021 was queried using the Accreditation Council for Graduate Medical Education (ACGME), and new radiology trainees using the National Resident Matching Program (NRMP)’s Main Residency Match Data and Reports databooks.

Results

In 2021 females represented 26.7% of DR residency trainees and 22% of IR integrated trainees. In the same year URM trainees represented 11.3% of trainees and 8.7% of IR integrated trainees. From 2017 to 2021, diagnostic radiology had a compound average growth rate (CAGR) 1% (p <0.01) of female representation and 1.12% (p<0.01) of URM representation.

Conclusion

This study quantifies female and underrepresented minority representation among radiology trainees for diagnostic radiology and radiology subspecialities, identifying modest uptrends in representation within both demographics.

合理而客观:过去二十年来,包括医疗保健在内的各行各业的多样性、公平性、包容性和代表性日益受到关注。在本报告中,我们调查了女性和代表性不足的少数族裔(URM)在放射学领域的代表性,并评估了美国住院医师培训项目中代表性的显著增长趋势:通过毕业后医学教育认证委员会(ACGME)查询了2016年至2021年在职放射学受训人员的去身份化受训人员人口统计学信息,并通过国家住院医师匹配计划(NRMP)的主要住院医师匹配数据和报告数据库查询了新的放射学受训人员:2021 年,女性占放射科住院医师培训学员的 26.7%,占放射科综合培训学员的 22%。同年,URM受训人员占11.3%,IR综合受训人员占8.7%。从 2017 年到 2021 年,放射诊断学的复合平均增长率(CAGR)为 1%(p 结论):本研究量化了放射诊断学和放射学亚专科中女性和代表人数不足的少数族裔受训人员的代表情况,确定了这两个人口统计中代表人数的适度上升趋势。
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引用次数: 0
Peer-to-Peer Medical Student Teaching in Radiology 放射学医学生点对点教学。
IF 1.5 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-03 DOI: 10.1067/j.cpradiol.2024.05.014

Medical students are often regarded purely as learners, but many can also perform well as educators. When more senior students are on service with underclassmen, especially when attendings and residents are busy, they can play an important role in helping to advance a radiology department's teaching mission.

医科学生通常被视为纯粹的学习者,但许多学生也能很好地发挥教育者的作用。当高年级学生与低年级学生一起工作时,尤其是当主治医生和住院医生忙碌时,他们可以在帮助推进放射科教学任务方面发挥重要作用。
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引用次数: 0
Which health conditions report the most spending on medical imaging? Evidence for Colombia 哪些健康状况在医学影像方面花费最多?哥伦比亚的证据。
IF 1.5 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-03 DOI: 10.1067/j.cpradiol.2024.05.003

Medical imaging is essential for the proper diagnosis and treatment of many diseases. The literature has found that medical imaging generally accounts for a significant percentage of total healthcare spending. We analyzed a national database between 2013 and 2021, with more than 19 million patients on average, to review which health conditions account for the highest spending on medical imaging in the Colombian health system. We segmented the analysis by type of medical imaging, life cycles, health condition and sex. Our findings indicate that cardiac and mental illnesses account for the highest per capita spending on medical imaging, especially for the elderly. As a proportion of total expenditure, hypertension and tuberculosis are added, with special emphasis on the infancy-childhood life cycle.

医学成像对许多疾病的正确诊断和治疗至关重要。文献发现,医学影像通常在医疗保健总支出中占很大比例。我们分析了 2013 年至 2021 年平均超过 1900 万名患者的全国数据库,以了解哥伦比亚医疗系统中哪些健康状况的医疗成像支出最高。我们按照医学影像类型、生命周期、健康状况和性别进行了细分分析。我们的研究结果表明,心脏病和精神疾病的人均医学影像支出最高,尤其是老年人。高血压和肺结核在总支出中所占的比例也有所增加,特别是在婴幼儿生命周期。
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引用次数: 0
Seminal vesicles in focus: An illustrated overview 聚焦精囊:图解概述
IF 1.5 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-21 DOI: 10.1067/j.cpradiol.2024.04.006

Seminal vesicles play a crucial role in the male reproductive system, as they are responsible for secreting a fluid that forms most of the ejaculate. Seminal vesicles' pathology can present with non-specific symptoms, making imaging diagnosis essential for proper patient management. Various imaging modalities can be used to evaluate these glands, with MRI beneficial in illustrating the spectrum of seminal vesicle disease. Typical seminal vesicles appear as elongated fluid-containing structures, but congenital anomalies, inflammatory conditions, and neoplastic disorders can alter their appearance. Furthermore, differentiating mimics from actual pathology can be challenging but crucial for proper management.

This article aims to provide an overview of the typical imaging appearance of the seminal vesicles and illustrate the principal imaging characteristics of conditions involving these structures. It will review the imaging characteristics of common and uncommon lesions involving the seminal vesicles by exploring congenital, infectious, and neoplastic in detail. As the seminal vesicles are often evaluated incidentally during prostate imaging, radiologists should be aware of the variability of normal findings and recognize the principal pathologies affecting these structures to ensure proper patient management.

精囊在男性生殖系统中起着至关重要的作用,因为它们负责分泌一种液体,这种液体构成了大部分射精。精囊病变可表现为非特异性症状,因此影像诊断对患者的正确治疗至关重要。各种成像模式都可用于评估这些腺体,其中核磁共振成像有利于显示精囊疾病的范围。典型的精囊表现为拉长的含液结构,但先天性异常、炎症和肿瘤性疾病会改变其外观。本文旨在概述精囊的典型影像学表现,并说明涉及这些结构的疾病的主要影像学特征。本文将通过详细探讨先天性、感染性和肿瘤性精囊病变,回顾涉及精囊的常见和不常见病变的影像学特征。由于精囊经常在前列腺成像时被偶然评估,因此放射科医生应了解正常检查结果的可变性,并认识到影响这些结构的主要病变,以确保对患者进行正确处理。
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引用次数: 0
Demographics and socioeconomic determinants of health predict continued participation in a CT lung cancer screening program 人口统计学和社会经济健康决定因素可预测是否继续参与 CT 肺癌筛查计划。
IF 1.5 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-21 DOI: 10.1067/j.cpradiol.2024.04.004

Purpose

We developed machine learning (ML) models to assess demographic and socioeconomic status (SES) variables’ value in predicting continued participation in a low-dose CT lung cancer screening (LCS) program.

Materials and Methods

480 LCS subjects were retrospectively examined for the following outcomes: (#1) no follow-up (single LCS scan) vs. multiple follow-ups (220 and 260 subjects respectively) and (#2) absent or delayed (>1 month past the due date) follow-up vs timely follow-up (356 and 124 subjects respectively). We quantified the contributions of 14 socioeconomic, demographic, and clinical predictors to LCS adherence, and validated and compared prediction performances of multivariate logistic regression (MLR), support vector machine (SVM) and shallow neural network (NN) models.

Results

For outcome #1, age, sex, race, insurance status, personal cancer history, and median household income were found to be associated with returning for follow-ups. For outcome #2, age, sex, race, and insurance status were significant predictor of absent/delayed LCS follow-up. Across 5-fold cross-validation, the MLR model achieved an average AUC of 0.732 (95% CI, 0.661-0.803) for outcome #1 and 0.633 (95% CI, 0.602-0.664) for outcome #2 and is the model with best predictive performance overall, whereas NN and SVM tended to overfit training data and fell short on testing data performance for either outcome.

Conclusions

We identified significant predictors of LCS adherence, and our ML models can predict which subjects are at higher risk of receiving no or delayed LCS follow-ups. Our results could inform data-driven interventions to engage vulnerable populations and extend the benefits of LCS.

材料与方法 我们对 480 名肺癌筛查受试者进行了回顾性研究,结果如下:(#1) 无随访(单次肺癌扫描)与多次随访(分别为 220 名和 260 名受试者);(#2) 缺席或延迟(超过到期日 1 个月)随访与及时随访(分别为 356 名和 124 名受试者)。我们量化了 14 个社会经济、人口统计学和临床预测因素对坚持 LCS 的贡献,并验证和比较了多元逻辑回归 (MLR)、支持向量机 (SVM) 和浅层神经网络 (NN) 模型的预测性能。结果对于结果 #1,我们发现年龄、性别、种族、保险状况、个人癌症病史和家庭收入中位数与返回随访相关。对于结果 2,年龄、性别、种族和保险状况是缺席/延迟 LCS 随访的重要预测因素。在 5 倍交叉验证中,MLR 模型对结果 #1 的平均 AUC 为 0.732(95% CI,0.661-0.803),对结果 #2 的平均 AUC 为 0.633(95% CI,0.602-0.664),是整体预测性能最好的模型,而 NN 和 SVM 则倾向于过拟合训练数据,对任何一个结果的测试数据性能都不理想。结论我们发现了LCS依从性的重要预测因素,我们的ML模型可以预测哪些受试者不接受或延迟接受LCS随访的风险较高。我们的研究结果可以为数据驱动的干预措施提供信息,以吸引弱势群体参与并扩大 LCS 的益处。
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引用次数: 0
ChatGPT: Evaluating answers on contrast media related questions and finetuning by providing the model with the ESUR guideline on contrast agents ChatGPT:评估造影剂相关问题的答案,并通过提供 ESUR 造影剂指南模型进行微调
IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-21 DOI: 10.1067/j.cpradiol.2024.04.005
Michael Scheschenja, Moritz B. Bastian, Joel Wessendorf, Andreas D. Owczarek, Alexander M. König, Simon Viniol , Andreas H. Mahnken

Objective

This study aimed to assess the feasibility of GPT-4 for answering questions related to contrast media with and without the context of the European Society of Urogenital Radiology (ESUR) guideline on contrast agents. The overarching goal was to determine whether contextual enrichment by providing guideline information improves answers of GPT-4 for clinical decision-making in radiology.

Methods

A set of 64 questions, based on the ESUR guideline on contrast agents mirroring pertinent sections, was developed and posed to GPT-4 both directly and after providing the guideline using a plugin. Responses were graded by experienced radiologists for quality of information and accuracy in pinpointing information from the guideline as well as by radiology residents for utility, using Likert-scales.

Results

GPT-4′s performance improved significantly with the guideline. Without the guideline, average quality rating was 3.98, which increased to 4.33 with the guideline (p = 0036). In terms of accuracy, 82.3% of answers matched the information from the guideline. Utility scores also reflected a significant improvement with the guideline, with average scores of 4.1 (without) and 4.4 (with) (p = 0.008) with a Fleiss´ Kappa of 0.44.

Conclusion

GPT-4, when contextually enriched with a guideline, demonstrates enhanced capability in providing guideline-backed recommendations. This approach holds promise for real-time clinical decision-support, making guidelines more actionable. However, further refinements are necessary to maximize the potential of large language models (LLMs). Inherent limitations need to be addressed.

目的本研究旨在评估 GPT-4 在有欧洲泌尿放射学会(ESUR)造影剂指南的背景下和没有该指南的背景下回答造影剂相关问题的可行性。方法根据欧洲泌尿放射学会造影剂指南的相关章节,开发了一套 64 个问题,并直接向 GPT-4 提出,或在使用插件提供指南后向 GPT-4 提出。由经验丰富的放射科医生根据信息质量和准确定位指南信息的情况进行评分,并由放射科住院医生根据实用性使用李克特量表进行评分。在没有该指南的情况下,平均质量评分为 3.98,而有了该指南后,评分增至 4.33(p = 0036)。在准确性方面,82.3% 的答案与指南中的信息相符。使用指南后,效用评分也有显著提高,平均分为 4.1(无指南)和 4.4(有指南)(p = 0.008),弗莱斯 Kappa 为 0.44。这种方法有望用于实时临床决策支持,使指南更具可操作性。然而,要最大限度地发挥大型语言模型(LLMs)的潜力,还需要进一步的改进。需要解决固有的局限性。
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引用次数: 0
Resection of colorectal carcinoma liver metastases: A population-based study in outcomes and factors associated with recurrent disease 结直肠癌肝转移灶切除术:基于人群的结果及复发相关因素研究
IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-21 DOI: 10.1067/j.cpradiol.2024.04.007
Andrew Fenwick MD , Curtis Black MD , Victoria Linehan MD PhD , Boris L. Gala-Lopez MD MSc PhD ASTS , Andreu F. Costa MD MSc FRCPC

Objective

To assess the hepatic disease-free survival (HDFS) and overall survival (OS) of patients who underwent resection of colorectal cancer liver metastases (CRCLM) in our population, and evaluate what factors are associated with these outcomes.

Methods

Patients with resected non-mucinous CRCLM between January 2013-February 2020 were retrospectively identified. Dates of diagnosis, surgery, and, if applicable, death were recorded. HDFS and OS were calculated using a census date of 24 September 2022. Separate Cox multivariate regression analyses were performed to evaluate for association between HDFS and OS and the following factors: pre-operative imaging interval (<4 weeks vs. ≥4 weeks); pre-operative imaging modality (CT only vs. MRI+CT); extrahepatic disease at time of hepatectomy (yes vs. no); tumor burden score (TBS, where TBS2 = (largest axial dimension of CRCLM)2 + (number of CRCLM)2); pT and pN; and neoadjuvant chemotherapy.

Results

137 subjects (mean age, 61 ± 11 years, 86 males) were included. Associations with recurrent hepatic disease were found with chemotherapy (HR 2.11[95 % CI = 1.13–3.92]), TBS (HR 1.30[95 % CI = 1.17–1.45]), MRI+CT (HR 2.12[95 % CI = 1.29–3.48]), and extrahepatic disease at hepatectomy (HR 2.16[95 % CI = 1.08–4.35]). For mortality, associations were found with TBS (HR 1.22[95 % CI = 1.09–1.37]), pT (HR 1.45[95 % CI = 1.05–2.00]), and extrahepatic disease at hepatectomy (HR 2.10[95 % CI = 1.31–3.36]).

Conclusion

In our population, non-imaging related factors TBS, neoadjuvant chemotherapy, pT and presence of extrahepatic disease at time of hepatectomy were associated with HDFS and/or OS. The preoperative imaging interval and use of preoperative MRI were not associated with improved patient outcomes.

目的 评估我国人群中接受结直肠癌肝转移灶(CRCLM)切除术的患者的肝脏无病生存期(HDFS)和总生存期(OS),并评估与这些结果相关的因素。方法 回顾性地确定 2013 年 1 月至 2020 年 2 月间接受非黏液性 CRCLM 切除术的患者。记录诊断日期、手术日期以及死亡日期(如适用)。以2022年9月24日为普查日期,计算HDFS和OS。分别进行了Cox多变量回归分析,以评估HDFS和OS与以下因素之间的关系:术前成像间隔(<4周 vs. ≥4周);术前成像方式(仅CT vs. MRI+CT);肝外血管造影(MRI+CT)。结果 共纳入 137 例受试者(平均年龄 61 ± 11 岁,男性 86 例)。化疗(HR 2.11[95 % CI = 1.13-3.92])、TBS(HR 1.30[95 % CI = 1.17-1.45])、MRI+CT(HR 2.12[95 % CI = 1.29-3.48])和肝切除术时的肝外疾病(HR 2.16[95 % CI = 1.08-4.35])与复发性肝病有关。结论在我们的研究人群中,非影像学相关因素TBS、新辅助化疗、pT和肝切除术时存在肝外疾病与HDFS和/或OS相关。术前成像间隔和术前磁共振成像的使用与患者预后的改善无关。
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引用次数: 0
期刊
Current Problems in Diagnostic Radiology
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