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Return to Sport After Revision Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis. 前交叉韧带重建后恢复运动:系统回顾和荟萃分析。
Pub Date : 2026-01-23 DOI: 10.1177/03635465251405493
Varun Gopinatth,Daniel C Touhey,Edward M Barksdale,Derrick M Knapik
BACKGROUNDRevision anterior cruciate ligament (ACL) reconstruction (ACLR) is a well-established procedure to restore knee stability and improve function after a failed primary ACLR. In active individuals, patient, injury, and operative variables influencing successful return to sport (RTS) after revision ACLR remain poorly understood.PURPOSETo evaluate RTS outcomes in patients undergoing revision ACLR.STUDY DESIGNMeta-analysis, Level of evidence, 4Methods:A systematic review was conducted in accordance with the 2020 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. A literature search was conducted by querying 5 databases from inception through January 2025 to identify studies reporting on RTS outcomes in athletes undergoing revision ACLR. Meta-analysis was performed using random-effects models at 95% confidence intervals, with odds ratios used for comparative studies.RESULTSA total of 52 studies, consisting of 3814 patients, met inclusion criteria. The mean patient age was 27.6 ± 8.4 years, with 66.3% (2340/3532) of the patients being male. Soccer was the most commonly reported sport (24.6%; 390/1584), followed by basketball (17.6%; 278/1584) and football (7.8%; 124/1584). The overall pooled RTS rate was 77.8% (95% CI, 0.732-0.824), with the RTS rate to the previous level of competition being 48.2% (95% CI, 0.410-0.553). The weighted mean time to RTS was 9.3 ± 2.7 months. Patients undergoing revision ACLR with the addition of a lateral extra-articular procedure (LEAP) had a significantly higher RTS rate (90.6% vs 74.9%; P < .00001), while greater articular cartilage damage was associated with less successful RTS (OR, 0.214; 95% CI, 0.078-0.584). The mean postoperative Anterior Cruciate Ligament Return to Sport after Injury score was 61.2 ± 24.1 (n = 535). The most commonly reported reason for failure to RTS or RTS at a lower competition level was fear of reinjury (28.0%; 142/508), followed by knee pain (12.0%; 61/508) and persistent instability (7.3%; 37/508).CONCLUSIONThe overall RTS rate after revision ACLR was 77.8%, with 48.2% returning to the previous level of competition. The addition of a LEAP led to improved RTS rates. Fear of reinjury was reported as the most commonly reported barrier to successful RTS.
背景:前交叉韧带(ACLR)重建(ACLR)是一种成熟的手术,用于恢复膝关节稳定性和改善原发性ACLR失败后的功能。在运动个体中,患者、损伤和手术变量对ACLR修订后成功恢复运动(RTS)的影响仍然知之甚少。目的评价改良ACLR患者的RTS预后。研究设计:荟萃分析,证据水平,4方法:根据2020年PRISMA(系统评价和荟萃分析的首选报告项目)指南进行系统评价。文献检索通过查询5个数据库从成立到2025年1月,以确定报道运动员进行修订ACLR的RTS结果的研究。meta分析采用随机效应模型,置信区间为95%,比值比用于比较研究。结果共有52项研究,3814例患者符合纳入标准。患者平均年龄27.6±8.4岁,男性占66.3%(2340/3532)。足球是最常见的运动(24.6%;390/1584),其次是篮球(17.6%;278/1584)和足球(7.8%;124/1584)。总体合并RTS率为77.8% (95% CI, 0.732-0.824),与之前竞争水平的RTS率为48.2% (95% CI, 0.410-0.553)。加权平均RTS时间为9.3±2.7个月。接受改良ACLR并增加外侧关节外手术(LEAP)的患者的RTS成功率明显更高(90.6% vs 74.9%; P < 0.00001),而更大的关节软骨损伤与更低的RTS成功率相关(OR, 0.214; 95% CI, 0.078-0.584)。术后前交叉韧带损伤后恢复运动的平均评分为61.2±24.1 (n = 535)。最常见的RTS失败原因是害怕再次受伤(28.0%,142/508),其次是膝盖疼痛(12.0%,61/508)和持续不稳定(7.3%,37/508)。结论修改ACLR后的总体RTS率为77.8%,其中48.2%恢复到原来的竞争水平。LEAP的加入提高了RTS率。对再次受伤的恐惧是成功RTS游戏最常见的障碍。
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引用次数: 0
The Effect of Lateral Extra-articular Tenodesis Femoral Fixation Methods on Graft Failure Rates in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis. 外侧关节外肌腱固定术对前交叉韧带重建移植物失败率的影响:一项系统回顾和荟萃分析。
Pub Date : 2026-01-23 DOI: 10.1177/03635465251405495
Matthew Charles Johnson,Ameer Tabbaa,Jesse Galina,Hardik Dabas,Orry Erez,Jorge Chahla,Andrew Pearle,Ron Gilat
BACKGROUNDAnterior cruciate ligament reconstruction augmented with modified-Lemaire lateral extra-articular tenodesis (ACLR+LET) improves rotational stability of the knee in patients with a moderate to high risk of graft failure. Early biomechanical data suggest divergent pullout strengths among various LET fixation methods, but their clinical significance remains to be determined.PURPOSETo evaluate graft rupture rates in ACLR+LET compared with ACLR alone, stratified by the method of LET femoral fixation.STUDY DESIGNSystematic review and meta-analysis; Level of evidence, 3.METHODSA systematic review was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines. A comprehensive search was conducted across PubMed, Embase, Scopus, and CENTRAL for studies that referenced Lateral Extra-articular Tenodesis and Modified Lemaire. A meta-analysis was performed with a significance threshold of .05.RESULTSA total of 1199 studies were screened, and 17 met the final inclusion criteria. Across these studies, 2527 patients who underwent ACLR were analyzed; 1254 underwent ACLR with LET augmentation. LET augmentation significantly reduced graft rupture rates compared with ACLR alone (odds ratio [OR], 2.90 [95% CI, 1.89-4.46]). Among ACLR+LET subgroups, anchor fixation demonstrated the greatest reduction in graft failure (OR, 4.93; P < .001), followed by staple fixation (OR, 3.04; P < .001). Other fixation methods-including button, suture, and screw-showed potential benefit, but individual results were not statistically significant (P > .05). Further analysis revealed that LET significantly reduced graft failure in primary ACLR (OR, 3.44; P = .00). LET-specific hardware removal was rare (0.82% [95% CI, 0.07%-2.10%]), with the highest rates seen in staple fixation, followed by anchor, and no events reported in the button and screw groups (1.58% vs 1.10% vs 0% vs 0%; P = .702).CONCLUSIONACLR+LET significantly reduces the risk of primary graft failure compared with ACLR alone. Among LET femoral fixation methods, anchor and staple fixation demonstrate the lowest ACL graft failure rates, with similar hardware removal rates.
背景:改良lemaire外侧关节外肌腱固定术(ACLR+LET)增强前交叉韧带重建可改善中度至高风险移植失败患者膝关节旋转稳定性。早期的生物力学数据表明,不同的LET固定方法的拔出强度不同,但其临床意义仍有待确定。目的评价ACLR+LET与单纯ACLR相比较,采用LET股内固定分层。研究设计:系统评价和荟萃分析;证据水平,3。方法按照PRISMA(系统评价和荟萃分析首选报告项目)指南进行系统评价。我们对PubMed、Embase、Scopus和CENTRAL进行了全面的检索,以查找有关外侧关节外肌腱固定术和改良Lemaire的研究。进行meta分析,显著性阈值为0.05。结果共筛选1199项研究,其中17项符合最终纳入标准。在这些研究中,2527例接受ACLR的患者被分析;1254例行ACLR伴LET增强。与单纯ACLR相比,LET增强显著降低了移植物破裂率(优势比[OR], 2.90 [95% CI, 1.89-4.46])。在ACLR+LET亚组中,锚钉固定能最大程度地减少移植物失败(OR, 4.93; P < 0.001),其次是钉钉固定(OR, 3.04; P < 0.001)。其他固定方法(包括钮扣、缝线和螺钉)显示出潜在的益处,但个别结果无统计学意义(P < 0.05)。进一步分析显示,LET可显著降低原发性ACLR的移植物衰竭(OR, 3.44; P = .00)。let特异性内固定清除非常罕见(0.82% [95% CI, 0.07%-2.10%]),钉钉固定发生率最高,其次是锚钉,钮扣和螺钉组未报告发生此类事件(1.58% vs 1.10% vs 0% vs 0%; P = 0.702)。结论与单纯ACLR相比,ACLR+LET可显著降低原发性移植物衰竭的风险。在LET股骨固定方法中,锚钉和钉钉固定显示出最低的ACL移植物失败率,其内固定物移除率相似。
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引用次数: 0
The Long-term Radiographic Fate of the Chronically ACL-Deficient Knee: A Systematic Review and Meta-analysis of Matched Cohort Studies. 慢性acl缺失膝关节的长期影像学预后:匹配队列研究的系统回顾和荟萃分析。
Pub Date : 2026-01-23 DOI: 10.1177/03635465251405438
Ajay Shah,Kosaran Gumarathas,Paul Marks,Robert G Marx,Alexander Kiss,David Wasserstein
BACKGROUNDDetermining the long-term risk of arthritis in patients with anterior cruciate ligament (ACL) injury treated nonoperatively versus those who undergo ACL reconstruction (ACLR) remains an important and unanswered question for patients and surgeons.PURPOSE(1) To define the cumulative arthritis rate and severity after nonsurgical management of ACL injury-the chronically ACL-deficient (ACLD) knee; (2) to compare rates and severity of arthritis in patients who have ACLD knee with similar patients who underwent ACLR; and (3) to identify clinically relevant risk factors for arthritis.STUDY DESIGNSystematic review; Level of evidence, 3.METHODSThree databases (Medline, Embase, PubMed) were searched for primary studies examining radiographic outcomes in patients with chronic ACL deficiency (>12 months of ACL deficiency). Studies with a matched ACLR control group were included. Quality assessment was performed with the MINORS (Methodological Index for Nonrandomized Studies) tool. Arthritis prevalence over time was plotted and modeled to best-fit using the Akaike information criterion. Data were extracted for meta-analysis for the primary outcome of osteoarthritis. The cumulative odds ratio of prognostic factors was calculated where appropriate.RESULTSNineteen full-text studies met inclusion criteria (11 matched cohort studies comparing ACLD and ACLR) including 1432 patients with a mean 11.1 years of follow-up after injury. The methodological quality of included studies was moderate. The pooled rate of radiographic arthritis in ACLD patients was 37.8%; the rate of moderate to severe arthritis was 18.1% (compared with 35.2% and 12.8% in patients with ACLR, respectively, and 5.0% in the nonoperated knee). An increase in the rate of arthritis was observed, accelerating sharply at 10 years after injury. ACLR and ACLD knees had similar prevalence of mild arthritis (P = .60), irrespective of activity level. Joint degeneration was significantly accelerated by meniscectomy in ACLD patients in most studies.CONCLUSIONPatients with a chronically ACLD knee may be at an increased predisposition for developing moderate to severe arthritis but not mild arthritis compared with matched patients who undergo ACLR. Meniscectomy is a key predictor of worsened severity of osteoarthritis.
背景:对于患者和外科医生来说,确定非手术治疗的前交叉韧带(ACL)损伤患者与接受ACL重建(ACLR)的患者患关节炎的长期风险仍然是一个重要且未解决的问题。目的(1)确定非手术治疗前交叉韧带损伤-慢性ACL缺陷(ACLD)膝关节后累积关节炎的发生率和严重程度;(2)比较膝关节ACLD患者与同类膝关节ACLR患者关节炎的发生率和严重程度;(3)识别关节炎的临床相关危险因素。研究设计:系统评价;证据水平,3。方法检索三个数据库(Medline, Embase, PubMed),检索慢性前交叉韧带缺陷(前交叉韧带缺陷12个月)患者影像学结果的初步研究。纳入匹配ACLR对照组的研究。采用未成年人(非随机研究方法学指数)工具进行质量评估。使用赤池信息标准绘制和建模关节炎患病率随时间的变化。提取数据进行骨关节炎主要转归的荟萃分析。在适当的地方计算预后因素的累积优势比。结果19项全文研究符合纳入标准(11项匹配队列研究比较ACLD和ACLR),包括1432例患者,损伤后平均随访11.1年。纳入研究的方法学质量一般。ACLD患者影像学关节炎合并率为37.8%;中度至重度关节炎的发生率为18.1% (ACLR患者分别为35.2%和12.8%,未手术膝关节患者为5.0%)。观察到关节炎发病率的增加,在受伤后10年急剧加速。与活动水平无关,ACLR和ACLD膝关节有相似的轻度关节炎患病率(P = 0.60)。在大多数研究中,半月板切除术显著加速了ACLD患者的关节退变。结论:慢性ACLD患者发生中度至重度关节炎的易感性高于ACLR患者,但不高于轻度关节炎的易感性。半月板切除术是骨关节炎严重程度恶化的关键预测指标。
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引用次数: 0
Outcomes of Hip Arthroscopy in Patients With Acetabular Cysts: A Multicenter Matched Controlled Study From the MASH Study Group. 髋臼囊肿患者的髋关节镜检查结果:来自MASH研究组的一项多中心匹配对照研究。
Pub Date : 2026-01-21 DOI: 10.1177/03635465251405731
Dean K Matsuda,Andrew B Wolff,Shane Nho,John J Christoforetti,John P Salvo,RobRoy L Martin,Ryan McGovern,Richard J Silk,Allysa Ishimoto,Brandon Ko,Dominic Carreira
BACKGROUNDSome studies have reported more severe chondral pathology and less successful hip arthroscopic outcomes in patients with acetabular subchondral cysts.PURPOSE/HYPOTHESISThe purpose of this study was to report multicenter arthroscopic outcomes of patients with and without acetabular bone cysts. It was hypothesized that patients with acetabular cysts would demonstrate inferior outcomes at minimum 2-year follow-up compared with patients without acetabular cysts.STUDY DESIGNCohort study; Level of evidence, 3.METHODSA multicenter matched-pair study was performed across 6 medical centers with data from a large prospectively collected database. Inclusion criteria were adult patients who had undergone primary unilateral hip arthroscopy for femoroacetabular impingement syndrome (FAIS). The study group was defined by the presence of a superolateral acetabular subchondral cyst on preoperative imaging. A control group was matched on age; sex; body mass index (BMI); lateral center-edge angle (LCEA); alpha angle; arthroscopic treatments of femoroplasty, acetabuloplasty, and labral treatment (ie, repair, reconstruction, or debridement); Beck chondral grade; and minimum 2-year outcomes using visual analog scale (VAS) for pain, International Hip Outcome Tool-12 (iHOT-12), minimal clinically important difference (MCID), substantial clinical benefit (SCB), and Patient Acceptable Symptom State (PASS).RESULTSThe study included 82 patients, of whom 41 composed the study group and 41 served as matched control patients. The study group had a mean age of 42.16 ± 11.26 years with 48.78% women and a mean BMI of 26.51 ± 4.31 kg/m2. Mean LCEA was 33.55°± 6.30°, and mean alpha angle was 70.22°± 9.71°. Mean Beck chondral grade was 2.59 ± 1.27 in the study group and 2.70 ± 0.95 in the matched control group (P = .72). Two-year mean postoperative iHOT-12 scores for the study and control groups were 69.49 ± 24.51 and 73.24 ± 25.16, respectively (P = .38), whereas mean postoperative VAS scores for pain were 18.84 ± 18.17 and 20.74 ± 21.39, respectively (P = .70). The study group reached MCID in 82.93%, SCB in 58.54%, and PASS in 65.85% and were similar to those of the control group.CONCLUSIONPatients undergoing arthroscopic surgery for FAIS with acetabular cysts had similarly successful outcomes as patients without acetabular cysts. Acetabular subchondral cysts may not be a contraindication to hip arthroscopy in patients with FAIS who would otherwise be indicated for this surgery.
一些研究报道了髋臼软骨下囊肿患者更严重的软骨病理和更不成功的髋关节镜结果。目的/假设本研究的目的是报道伴有和不伴有髋臼骨囊肿患者的多中心关节镜结果。假设髋臼囊肿患者与无髋臼囊肿患者相比,在至少2年的随访中表现出较差的预后。研究设计:队列研究;证据水平,3。方法在6个医疗中心进行了一项多中心配对研究,数据来自一个大型前瞻性数据库。纳入标准是因股髋臼撞击综合征(FAIS)接受过原发性单侧髋关节镜检查的成年患者。研究组的定义是术前影像学显示髋臼上外侧软骨下囊肿。对照组按年龄配对;性;体重指数(BMI);侧中心角(LCEA);α角;关节镜下的股骨成形术、髋臼成形术和唇部治疗(即修复、重建或清创);贝克软骨级;以及使用视觉模拟疼痛量表(VAS)、国际髋关节预后工具-12 (iHOT-12)、最小临床重要差异(MCID)、实质性临床获益(SCB)和患者可接受症状状态(PASS)的最小2年结果。结果共纳入82例患者,其中研究组41例,对照组41例。研究组平均年龄为42.16±11.26岁,女性占48.78%,平均BMI为26.51±4.31 kg/m2。平均LCEA为33.55°±6.30°,平均α角为70.22°±9.71°。研究组的平均贝克软骨分级为2.59±1.27,对照组的平均贝克软骨分级为2.70±0.95 (P = 0.72)。研究组和对照组术后两年平均iHOT-12评分分别为69.49±24.51和73.24±25.16分(P = 0.38),而疼痛VAS评分分别为18.84±18.17和20.74±21.39分(P = 0.70)。研究组达到MCID率为82.93%,达到SCB率为58.54%,达到PASS率为65.85%,与对照组相似。结论经关节镜手术治疗伴有髋臼囊肿的FAIS患者与无髋臼囊肿的患者预后相似。髋臼软骨下囊肿可能不是FAIS患者髋关节镜检查的禁忌症。
{"title":"Outcomes of Hip Arthroscopy in Patients With Acetabular Cysts: A Multicenter Matched Controlled Study From the MASH Study Group.","authors":"Dean K Matsuda,Andrew B Wolff,Shane Nho,John J Christoforetti,John P Salvo,RobRoy L Martin,Ryan McGovern,Richard J Silk,Allysa Ishimoto,Brandon Ko,Dominic Carreira","doi":"10.1177/03635465251405731","DOIUrl":"https://doi.org/10.1177/03635465251405731","url":null,"abstract":"BACKGROUNDSome studies have reported more severe chondral pathology and less successful hip arthroscopic outcomes in patients with acetabular subchondral cysts.PURPOSE/HYPOTHESISThe purpose of this study was to report multicenter arthroscopic outcomes of patients with and without acetabular bone cysts. It was hypothesized that patients with acetabular cysts would demonstrate inferior outcomes at minimum 2-year follow-up compared with patients without acetabular cysts.STUDY DESIGNCohort study; Level of evidence, 3.METHODSA multicenter matched-pair study was performed across 6 medical centers with data from a large prospectively collected database. Inclusion criteria were adult patients who had undergone primary unilateral hip arthroscopy for femoroacetabular impingement syndrome (FAIS). The study group was defined by the presence of a superolateral acetabular subchondral cyst on preoperative imaging. A control group was matched on age; sex; body mass index (BMI); lateral center-edge angle (LCEA); alpha angle; arthroscopic treatments of femoroplasty, acetabuloplasty, and labral treatment (ie, repair, reconstruction, or debridement); Beck chondral grade; and minimum 2-year outcomes using visual analog scale (VAS) for pain, International Hip Outcome Tool-12 (iHOT-12), minimal clinically important difference (MCID), substantial clinical benefit (SCB), and Patient Acceptable Symptom State (PASS).RESULTSThe study included 82 patients, of whom 41 composed the study group and 41 served as matched control patients. The study group had a mean age of 42.16 ± 11.26 years with 48.78% women and a mean BMI of 26.51 ± 4.31 kg/m2. Mean LCEA was 33.55°± 6.30°, and mean alpha angle was 70.22°± 9.71°. Mean Beck chondral grade was 2.59 ± 1.27 in the study group and 2.70 ± 0.95 in the matched control group (P = .72). Two-year mean postoperative iHOT-12 scores for the study and control groups were 69.49 ± 24.51 and 73.24 ± 25.16, respectively (P = .38), whereas mean postoperative VAS scores for pain were 18.84 ± 18.17 and 20.74 ± 21.39, respectively (P = .70). The study group reached MCID in 82.93%, SCB in 58.54%, and PASS in 65.85% and were similar to those of the control group.CONCLUSIONPatients undergoing arthroscopic surgery for FAIS with acetabular cysts had similarly successful outcomes as patients without acetabular cysts. Acetabular subchondral cysts may not be a contraindication to hip arthroscopy in patients with FAIS who would otherwise be indicated for this surgery.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"123 1","pages":"3635465251405731"},"PeriodicalIF":0.0,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of Contralateral Patellar Instability After Ipsilateral Medial Patellofemoral Ligament Reconstruction. 同侧髌股内侧韧带重建后对侧髌骨不稳的预测。
Pub Date : 2026-01-21 DOI: 10.1177/03635465251401561
Ali Asma,Samir Sharrak,Marcus A Shelby,Matthew Veerkamp,Shital N Parikh
BACKGROUNDAbout 10% to 16% of patients with patellar instability have bilateral involvement. The risk factors for future contralateral patellar instability in patients who have ipsilateral patellar instability are not known. Knowledge related to the possibility of future contralateral patellar instability would be helpful, as previous studies have shown suboptimal outcomes and increased complication rates in patients with bilateral patellar instability.PURPOSEThe purpose of the current study was to identify the risk factors for future contralateral patellar instability and develop a prediction model for contralateral patellar instability.STUDY DESIGNCase series; Level of evidence, 4.METHODSUsing a hospital-based surgery database from 2012 to 2022, all patients who underwent medial patellofemoral ligament (MPFL) reconstruction were identified. Age, sex, skeletal maturity, body mass index, generalized joint hypermobility (defined as a Beighton score ≥5), and first-time versus recurrent ipsilateral patellar dislocation were noted. There were 4 anatomic risk factors-trochlear depth, Caton-Deschamps index, tibial tubercle-trochlear groove distance, and patellar tilt-assessed on magnetic resonance imaging of the ipsilateral knee. Multivariable backward conditional logistic regression analysis was performed to identify the risk factors for contralateral patellar instability. A simplified prediction model for contralateral patellar instability was developed based on the number of risk factors.RESULTSDuring the study period, 380 knees in 293 patients underwent MPFL reconstruction and formed the study cohort. The mean age at surgery was 14.7 ± 2.7 years. 243 ipsilateral knees (63.9%) were female, and 168 (44.2%) were skeletally immature. 83 knees (21.8%) had a first-time dislocation, while 297 (78.2%) had a recurrent dislocation. Of these 380 knees, 130 (34.2%) had future contralateral patellar instability. On multivariable regression analysis, skeletal immaturity (odds ratio [OR], 1.90 [95% CI, 1.20-3.00]), generalized joint hypermobility (OR, 2.80 [95% CI, 1.50-5.10]), recurrent patellar instability in the ipsilateral knee (OR, 2.00 [95% CI, 1.10-3.70]), trochlear dysplasia in the ipsilateral knee (OR, 1.90 [95% CI, 1.05-3.40]), and patella alta in the ipsilateral knee (OR, 1.80 [95% CI, 0.96-3.30]) comprised the final model to predict contralateral patellar instability. As per the prediction model, the risk of future contralateral patellar instability was 9.2% if there was no risk factor present and 77.8% if all 5 risk factors were present.CONCLUSIONSkeletal immaturity, recurrent patellar instability in the involved knee, generalized joint hypermobility (Beighton score ≥5), trochlear dysplasia in the involved knee, and patella alta in the involved knee could help to predict contralateral patellar instability.
背景:大约10% - 16%的髌骨不稳患者有双侧受累。同侧髌骨不稳定患者未来对侧髌骨不稳定的危险因素尚不清楚。了解未来对侧髌骨不稳定的可能性是有帮助的,因为之前的研究表明双侧髌骨不稳定患者的预后不理想,并发症发生率增加。目的本研究的目的是确定未来对侧髌骨不稳定的危险因素,并建立对侧髌骨不稳定的预测模型。研究设计案例系列;证据等级,4级。方法使用2012年至2022年医院外科数据库,对所有接受内侧髌股韧带(MPFL)重建的患者进行识别。记录年龄、性别、骨骼成熟度、体重指数、全身性关节过度活动(定义为Beighton评分≥5)以及首次与复发性同侧髌骨脱位。在同侧膝关节的磁共振成像上评估滑车深度、卡顿-德尚指数、胫骨结节-滑车沟距离和髌骨倾斜4个解剖危险因素。采用多变量后向条件logistic回归分析确定对侧髌骨不稳的危险因素。建立了基于危险因素数量的对侧髌骨不稳定的简化预测模型。结果在研究期间,293例患者380例膝关节行强韧带重建,形成研究队列。平均手术年龄14.7±2.7岁。同侧膝关节243例(63.9%)为女性,168例(44.2%)为骨未成熟。83例(21.8%)膝关节首次脱位,297例(78.2%)膝关节复发脱位。在这380个膝关节中,130个(34.2%)有对侧髌骨不稳。在多变量回归分析中,骨骼不成熟(优势比[OR], 1.90 [95% CI, 1.20-3.00])、全身性关节过度活动(OR, 2.80 [95% CI, 1.50-5.10])、同侧膝关节复发性髌骨不稳(OR, 2.00 [95% CI, 1.10-3.70])、同侧膝关节滑车发育不良(OR, 1.90 [95% CI, 1.05-3.40])和同侧膝关节高位髌骨(OR, 1.80 [95% CI, 0.96-3.30])构成了预测对侧髌骨不稳的最终模型。根据预测模型,如果不存在危险因素,未来对侧髌骨不稳的风险为9.2%,如果5种危险因素都存在,未来对侧髌骨不稳的风险为77.8%。结论骨骼发育不成熟、受累膝复发性髌骨不稳、关节全身性活动过度(Beighton评分≥5)、受累膝滑车发育不良、受累膝高位髌骨有助于预测对侧髌骨不稳。
{"title":"Prediction of Contralateral Patellar Instability After Ipsilateral Medial Patellofemoral Ligament Reconstruction.","authors":"Ali Asma,Samir Sharrak,Marcus A Shelby,Matthew Veerkamp,Shital N Parikh","doi":"10.1177/03635465251401561","DOIUrl":"https://doi.org/10.1177/03635465251401561","url":null,"abstract":"BACKGROUNDAbout 10% to 16% of patients with patellar instability have bilateral involvement. The risk factors for future contralateral patellar instability in patients who have ipsilateral patellar instability are not known. Knowledge related to the possibility of future contralateral patellar instability would be helpful, as previous studies have shown suboptimal outcomes and increased complication rates in patients with bilateral patellar instability.PURPOSEThe purpose of the current study was to identify the risk factors for future contralateral patellar instability and develop a prediction model for contralateral patellar instability.STUDY DESIGNCase series; Level of evidence, 4.METHODSUsing a hospital-based surgery database from 2012 to 2022, all patients who underwent medial patellofemoral ligament (MPFL) reconstruction were identified. Age, sex, skeletal maturity, body mass index, generalized joint hypermobility (defined as a Beighton score ≥5), and first-time versus recurrent ipsilateral patellar dislocation were noted. There were 4 anatomic risk factors-trochlear depth, Caton-Deschamps index, tibial tubercle-trochlear groove distance, and patellar tilt-assessed on magnetic resonance imaging of the ipsilateral knee. Multivariable backward conditional logistic regression analysis was performed to identify the risk factors for contralateral patellar instability. A simplified prediction model for contralateral patellar instability was developed based on the number of risk factors.RESULTSDuring the study period, 380 knees in 293 patients underwent MPFL reconstruction and formed the study cohort. The mean age at surgery was 14.7 ± 2.7 years. 243 ipsilateral knees (63.9%) were female, and 168 (44.2%) were skeletally immature. 83 knees (21.8%) had a first-time dislocation, while 297 (78.2%) had a recurrent dislocation. Of these 380 knees, 130 (34.2%) had future contralateral patellar instability. On multivariable regression analysis, skeletal immaturity (odds ratio [OR], 1.90 [95% CI, 1.20-3.00]), generalized joint hypermobility (OR, 2.80 [95% CI, 1.50-5.10]), recurrent patellar instability in the ipsilateral knee (OR, 2.00 [95% CI, 1.10-3.70]), trochlear dysplasia in the ipsilateral knee (OR, 1.90 [95% CI, 1.05-3.40]), and patella alta in the ipsilateral knee (OR, 1.80 [95% CI, 0.96-3.30]) comprised the final model to predict contralateral patellar instability. As per the prediction model, the risk of future contralateral patellar instability was 9.2% if there was no risk factor present and 77.8% if all 5 risk factors were present.CONCLUSIONSkeletal immaturity, recurrent patellar instability in the involved knee, generalized joint hypermobility (Beighton score ≥5), trochlear dysplasia in the involved knee, and patella alta in the involved knee could help to predict contralateral patellar instability.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"48 1","pages":"3635465251401561"},"PeriodicalIF":0.0,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception of Pain and Function Among Athletes and Parents: A PROMIS Dyad Study. 运动员和家长对疼痛和功能的感知:一项PROMIS双元研究。
Pub Date : 2026-01-21 DOI: 10.1177/03635465251407113
Corinna C Franklin,Emily Nice,Kevin Moran, , ,Eric Heidel,Jeremy Bauer
BACKGROUNDAthletes can be profoundly impacted by their environment and support system. For young, injured athletes, parents may wield significant influence over their treatment and recovery, yet may hold divergent perceptions of the athletes' condition.HYPOTHESISWhen using the Patient-Reported Outcomes Measurement Information System (PROMIS) metrics, parents and athletes will have differing perceptions about how the athletes are affected by their injury.STUDY DESIGNCohort study; Level of evidence, 3.METHODSThis study was approved by our institutional review board. In our clinics, each child (age, 8-17 years) routinely takes a series of PROMIS questionnaires. For study purposes, at 1 sports clinic visit per child, we had an accompanying parent independently complete the same PROMIS metrics on the child's behalf. We then formed dyads from each athlete/parent response and used these dyads for analysis to quantify differences in their understanding. Generalized estimating equations were used to analyze differences between members of the dyads (correlated data).RESULTSThe total number of dyads examined was 387. There were 201 female athletes, 186 male athletes, 302 female parents, and 85 male parents. The mean age of both male and female athletes was 14 years. Across all dyads, parents rated pain interference as worse than patients did, by a mean of 5 points (mean score, 50.03 vs 45.46, respectively; P < .001). Significant differences were also noted in peer relationships, mobility, and upper-extremity PROMIS domains. In all domains, parents rated the patients as doing worse than the athletes did themselves. When examined by sport, parents of athletes in football, soccer, gymnastics, and basketball rated pain interference as worse. Parents of athletes treated both operatively and nonoperatively rated pain interference as higher, and parents of both sexes rated pain interference as higher.CONCLUSIONParents of injured athletes perceive their children to be more affected by pain than the athletes themselves. Parents also perceive injured athletes to have worse function across all domains than the athletes themselves do.
运动员会受到环境和支持系统的深刻影响。对于年轻的受伤运动员,父母可能对他们的治疗和康复有很大的影响,但可能对运动员的状况有不同的看法。假设当使用患者报告结果测量信息系统(PROMIS)指标时,家长和运动员对运动员受伤的影响有不同的看法。研究设计:队列研究;证据水平,3。方法本研究经我们的机构审查委员会批准。在我们的诊所里,每个孩子(8-17岁)都会定期接受一系列PROMIS问卷调查。为了研究目的,在每个孩子1次运动诊所就诊时,我们让陪同的父母代表孩子独立完成相同的PROMIS指标。然后,我们从每个运动员/家长的回答中形成二对组合,并使用这些二对组合进行分析,以量化他们在理解上的差异。使用广义估计方程来分析二组成员(相关数据)之间的差异。结果共检出387对。女运动员201人,男运动员186人,女家长302人,男家长85人。男性和女性运动员的平均年龄是14年。在所有夫妇中,父母对疼痛干扰的评分比患者差5分(平均评分分别为50.03比45.46,P < 0.001)。在同伴关系、移动性和上肢PROMIS域方面也存在显著差异。在所有方面,家长对病人的评价都比运动员自己差。当对体育项目进行调查时,橄榄球、足球、体操和篮球运动员的父母认为疼痛干扰更严重。接受手术和非手术治疗的运动员家长对疼痛干扰的评分更高,男女家长对疼痛干扰的评分都更高。结论受伤运动员家长对孩子疼痛的感受比运动员自身更强烈。父母也认为受伤的运动员在所有领域的功能都比运动员自己差。
{"title":"Perception of Pain and Function Among Athletes and Parents: A PROMIS Dyad Study.","authors":"Corinna C Franklin,Emily Nice,Kevin Moran, , ,Eric Heidel,Jeremy Bauer","doi":"10.1177/03635465251407113","DOIUrl":"https://doi.org/10.1177/03635465251407113","url":null,"abstract":"BACKGROUNDAthletes can be profoundly impacted by their environment and support system. For young, injured athletes, parents may wield significant influence over their treatment and recovery, yet may hold divergent perceptions of the athletes' condition.HYPOTHESISWhen using the Patient-Reported Outcomes Measurement Information System (PROMIS) metrics, parents and athletes will have differing perceptions about how the athletes are affected by their injury.STUDY DESIGNCohort study; Level of evidence, 3.METHODSThis study was approved by our institutional review board. In our clinics, each child (age, 8-17 years) routinely takes a series of PROMIS questionnaires. For study purposes, at 1 sports clinic visit per child, we had an accompanying parent independently complete the same PROMIS metrics on the child's behalf. We then formed dyads from each athlete/parent response and used these dyads for analysis to quantify differences in their understanding. Generalized estimating equations were used to analyze differences between members of the dyads (correlated data).RESULTSThe total number of dyads examined was 387. There were 201 female athletes, 186 male athletes, 302 female parents, and 85 male parents. The mean age of both male and female athletes was 14 years. Across all dyads, parents rated pain interference as worse than patients did, by a mean of 5 points (mean score, 50.03 vs 45.46, respectively; P < .001). Significant differences were also noted in peer relationships, mobility, and upper-extremity PROMIS domains. In all domains, parents rated the patients as doing worse than the athletes did themselves. When examined by sport, parents of athletes in football, soccer, gymnastics, and basketball rated pain interference as worse. Parents of athletes treated both operatively and nonoperatively rated pain interference as higher, and parents of both sexes rated pain interference as higher.CONCLUSIONParents of injured athletes perceive their children to be more affected by pain than the athletes themselves. Parents also perceive injured athletes to have worse function across all domains than the athletes themselves do.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"29 1","pages":"3635465251407113"},"PeriodicalIF":0.0,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anterior Cruciate Ligament Reconstruction With Hamstring Autografts and Suture Tape Augmentation Results in Lower Failure Rates While Maintaining Functional Outcomes and Complication Rates Similar to Nonaugmented Techniques: A Systematic Review and Meta-analysis. 与非增强技术相比,自体腿筋和缝合带增强前交叉韧带重建的失败率更低,同时保持功能结局和并发症发生率相似:一项系统回顾和荟萃分析。
Pub Date : 2026-01-21 DOI: 10.1177/03635465251400346
Rodrigo Bernstein Conde,André Richard da Silva Oliveira Filho,Elcio Machinski,Vinícius Furtado da Cruz,Bruno Butturi Varone,Riccardo Gomes Gobbi,Camilo Partezani Helito,Andre Giardino Moreira da Silva,Daniel Peixoto Leal
BACKGROUNDAnterior cruciate ligament reconstruction with suture augmentation (ACLR-SA) has been explored for its potential to provide additional graft protection.PURPOSETo compare failure rates, complications, patient-reported outcomes, and return to sport between ACLR-SA and nonaugmented ACLR.STUDY DESIGNSystematic review and meta-analysis; Level of evidence, 2.METHODSRandomized controlled trials and quasi-experimental studies were included if they provided data on population (patients with anterior cruciate ligament tear), intervention (ACLR-SA regardless of SA material and graft type), comparator (nonaugmented ACLR), and outcomes (failure, arthrofibrosis and cyclops, subsequent meniscal surgery, hardware removal, Lysholm and International Knee Documentation Committee scores, and/or return to sport).RESULTSEleven articles (1179 patients) were included. ACLR performed with hamstring autograft augmented with FiberTape reduced failure rates as compared with nonaugmented ACLR (3.1% vs 8.5%; odds ratio [OR], 2.86; 95% CI, 1.03-7.90; P = .043; I2 = 0%). In addition, the 2 techniques showed no differences in arthrofibrosis/cyclops (OR, 0.94; 95% CI, 0.26-3.33; P = .919; I2 = 0%), subsequent meniscal surgery (OR, 1.05; 95% CI, 0.32-3.44; P = .942; I2 = 0%), International Knee Documentation Committee score (mean difference, -1.20; 95% CI, -3.06 to 0.06; P = .206; I2 = 0%), and Lysholm score (mean difference, -0.96; 95% CI, -4.53 to 2.61; P = .597; I2 = 65%). When the FiberWire was utilized for hamstring autograft suture augmentation, no significant differences in failure rates were observed between groups. The pooled synthesis for all graft and augmentation combinations showed that ACLR-SA was associated with an increased return to preinjury activity level (72.5% vs 54.0%; OR, 0.44; 95% CI, 0.21-0.91; P = .027; I2 = 0%).CONCLUSIONAvailable evidence supports the use of suture tape augmentation in ACLRs performed with hamstring autografts, as it reduces failure rates while maintaining equivalent complication rates and patient-reported outcomes as compared with nonaugmented ACLR.
背景:前交叉韧带重建与缝线增强(ACLR-SA)已被探索其潜在的提供额外的移植物保护。目的比较ACLR- sa和非增强型ACLR的失败率、并发症、患者报告的结果和重返运动。研究设计:系统评价和荟萃分析;证据等级2。方法随机对照试验和准实验研究纳入,如果它们提供了人群(前交叉韧带撕裂患者)、干预(ACLR-SA,无论SA材料和移植物类型)、比较(非增强ACLR)和结果(失败、关节纤维化和cyclops、随后的半月板手术、硬件移除、Lysholm和国际膝关节文献委员会评分和/或恢复运动)的数据。结果纳入文献7篇(1179例)。与未增强的ACLR相比,FiberTape增强的腿筋自体移植物行ACLR降低了失败率(3.1% vs 8.5%;比值比[OR], 2.86; 95% CI, 1.03-7.90; P = 0.043; I2 = 0%)。此外,两种技术在关节纤维化/独眼症(OR, 0.94; 95% CI, 0.26-3.33; P = 0.919; I2 = 0%)、随后的半月板手术(OR, 1.05; 95% CI, 0.32-3.44; P = 0.942; I2 = 0%)、国际膝关节文献委员会评分(平均差值,-1.20;95% CI, -3.06 - 0.06; P = 0.206; I2 = 0%)和Lysholm评分(平均差值,-0.96;95% CI, -4.53 - 2.61; P = 0.597; I2 = 65%)方面均无差异。当FiberWire用于腘绳肌腱自体缝合增强时,两组间的失败率无显著差异。所有移植物和增强物组合的综合分析显示,ACLR-SA与损伤前活动水平的恢复增加相关(72.5% vs 54.0%; OR, 0.44; 95% CI, 0.21-0.91; P = 0.027; I2 = 0%)。结论现有证据支持在自体腘绳肌腱移植的ACLR中使用缝合带增强,因为与未增强的ACLR相比,它降低了失败率,同时保持了相同的并发症发生率和患者报告的结果。
{"title":"Anterior Cruciate Ligament Reconstruction With Hamstring Autografts and Suture Tape Augmentation Results in Lower Failure Rates While Maintaining Functional Outcomes and Complication Rates Similar to Nonaugmented Techniques: A Systematic Review and Meta-analysis.","authors":"Rodrigo Bernstein Conde,André Richard da Silva Oliveira Filho,Elcio Machinski,Vinícius Furtado da Cruz,Bruno Butturi Varone,Riccardo Gomes Gobbi,Camilo Partezani Helito,Andre Giardino Moreira da Silva,Daniel Peixoto Leal","doi":"10.1177/03635465251400346","DOIUrl":"https://doi.org/10.1177/03635465251400346","url":null,"abstract":"BACKGROUNDAnterior cruciate ligament reconstruction with suture augmentation (ACLR-SA) has been explored for its potential to provide additional graft protection.PURPOSETo compare failure rates, complications, patient-reported outcomes, and return to sport between ACLR-SA and nonaugmented ACLR.STUDY DESIGNSystematic review and meta-analysis; Level of evidence, 2.METHODSRandomized controlled trials and quasi-experimental studies were included if they provided data on population (patients with anterior cruciate ligament tear), intervention (ACLR-SA regardless of SA material and graft type), comparator (nonaugmented ACLR), and outcomes (failure, arthrofibrosis and cyclops, subsequent meniscal surgery, hardware removal, Lysholm and International Knee Documentation Committee scores, and/or return to sport).RESULTSEleven articles (1179 patients) were included. ACLR performed with hamstring autograft augmented with FiberTape reduced failure rates as compared with nonaugmented ACLR (3.1% vs 8.5%; odds ratio [OR], 2.86; 95% CI, 1.03-7.90; P = .043; I2 = 0%). In addition, the 2 techniques showed no differences in arthrofibrosis/cyclops (OR, 0.94; 95% CI, 0.26-3.33; P = .919; I2 = 0%), subsequent meniscal surgery (OR, 1.05; 95% CI, 0.32-3.44; P = .942; I2 = 0%), International Knee Documentation Committee score (mean difference, -1.20; 95% CI, -3.06 to 0.06; P = .206; I2 = 0%), and Lysholm score (mean difference, -0.96; 95% CI, -4.53 to 2.61; P = .597; I2 = 65%). When the FiberWire was utilized for hamstring autograft suture augmentation, no significant differences in failure rates were observed between groups. The pooled synthesis for all graft and augmentation combinations showed that ACLR-SA was associated with an increased return to preinjury activity level (72.5% vs 54.0%; OR, 0.44; 95% CI, 0.21-0.91; P = .027; I2 = 0%).CONCLUSIONAvailable evidence supports the use of suture tape augmentation in ACLRs performed with hamstring autografts, as it reduces failure rates while maintaining equivalent complication rates and patient-reported outcomes as compared with nonaugmented ACLR.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"101 1","pages":"3635465251400346"},"PeriodicalIF":0.0,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of 3 Forms of Clinically Available Hydroxyapatite Artificial Bone for Use in Biphasic Implants With Synovial Mesenchymal Stem Cell-Derived Tissue-Engineered Constructs for Osteochondral Repair. 三种羟基磷灰石人工骨在滑膜间充质干细胞衍生组织工程结构双相骨软骨修复中的应用比较
Pub Date : 2026-01-21 DOI: 10.1177/03635465251407260
Kazunori Shimomura,Seido Yarimitsu,George Jacob,Taro Akimori,Masato Nakamura,Wataru Ando,David A Hart,Hiromichi Fujie,Seiji Okada,Norimasa Nakamura
BACKGROUNDOsteochondral injuries, involving damage to both cartilage and subchondral bone, require a biphasic regenerative approach. A previous study demonstrated that a biphasic implant, composed of a hydroxyapatite (HA) block for the bone layer and a scaffold-free synovial mesenchymal stem cell-derived tissue-engineered construct (TEC) for the cartilage layer, successfully repaired osteochondral defects in a rabbit model. To facilitate less invasive surgical application, the authors investigated alternative HA forms including granules and paste for use in the subchondral component for the biphasic implant.HYPOTHESISBiphasic implants composed of TEC combined with either HA granules or HA paste would potentially achieve successful osteochondral repair, comparable to that of a conventional HA block-based implant.STUDY DESIGNControlled laboratory study.METHODSBilateral osteochondral defects (5 mm in diameter and 6 mm in depth) were created in the femoral grooves of rabbits and treated with a TEC combined with 1 of 3 HA forms: block, granules, or paste. Histological and biomechanical analyses were performed at 4, 8, and 24 weeks postimplantation (5 per group per time point).RESULTSThe TEC/HA block group achieved complete osteochondral repair with stable maturation, and the repaired tissue demonstrated biomechanical properties comparable to native tissue at 24 weeks postimplantation. In contrast, the TEC/HA granule group showed early signs of repair that progressively deteriorated, resulting in significantly inferior structural and mechanical properties. The TEC/HA paste group supported subchondral bone repair but resulted in incomplete cartilage formation at 24 weeks postimplantation.CONCLUSIONThe TEC/HA block implant showed superior histological and biomechanical outcomes compared with other HA forms. Therefore, further optimization of granular or paste formulation is required to possibly enhance the potential for arthroscopic or minimally invasive delivery of a biphasic implant.CLINICAL RELEVANCEThis study highlights the potential of biphasic implants combining clinically available TEC and HA artificial bone for osteochondral repair. The biphasic implant can be easily prepared intraoperatively without specialized fabrication. Long-term observations revealed distinct repair patterns for each HA form, which may assist surgeons in selecting the optimal HA artificial bone form for effective and durable subchondral bone repair in osteochondral regeneration.
软骨损伤包括软骨和软骨下骨的损伤,需要双期再生入路。先前的一项研究表明,由羟基磷灰石(HA)块体用于骨层和无支架滑膜间充质干细胞衍生的组织工程构建体(TEC)组成的双相植入物用于软骨层,成功修复了兔模型的骨软骨缺损。为了方便微创手术应用,作者研究了可替代的透明质酸形式,包括颗粒和糊状,用于双相植入物的软骨下组件。假设由TEC结合透明质酸颗粒或透明质酸糊状物组成的双相植入物可能成功实现骨软骨修复,与传统的HA块基植入物相当。研究设计:对照实验室研究。方法在兔股沟内制造双侧骨软骨缺损(直径5mm,深度6mm),用TEC联合HA(块状、颗粒状或膏状)3种形式中的1种治疗。在植入后4周、8周和24周进行组织学和生物力学分析(每组每个时间点5例)。结果TEC/HA阻断组实现了完整的骨软骨修复,成熟稳定,修复后的组织在植入后24周表现出与天然组织相当的生物力学特性。相比之下,TEC/HA颗粒组表现出逐渐恶化的早期修复迹象,导致结构和机械性能明显下降。TEC/HA膏剂组支持软骨下骨修复,但在植入后24周导致软骨形成不完全。结论TEC/HA块植入物与其他HA块植入物相比具有更好的组织学和生物力学效果。因此,需要进一步优化颗粒或膏状制剂,以可能提高关节镜下或微创植入双相植入物的潜力。临床意义:本研究强调了双期种植体结合临床可用的TEC和HA人工骨用于骨软骨修复的潜力。双相种植体可以很容易地在术中准备,无需专门制作。长期观察揭示了每种HA形式的不同修复模式,这可能有助于外科医生在骨软骨再生中选择最佳的HA人工骨形式进行有效和持久的软骨下骨修复。
{"title":"Comparison of 3 Forms of Clinically Available Hydroxyapatite Artificial Bone for Use in Biphasic Implants With Synovial Mesenchymal Stem Cell-Derived Tissue-Engineered Constructs for Osteochondral Repair.","authors":"Kazunori Shimomura,Seido Yarimitsu,George Jacob,Taro Akimori,Masato Nakamura,Wataru Ando,David A Hart,Hiromichi Fujie,Seiji Okada,Norimasa Nakamura","doi":"10.1177/03635465251407260","DOIUrl":"https://doi.org/10.1177/03635465251407260","url":null,"abstract":"BACKGROUNDOsteochondral injuries, involving damage to both cartilage and subchondral bone, require a biphasic regenerative approach. A previous study demonstrated that a biphasic implant, composed of a hydroxyapatite (HA) block for the bone layer and a scaffold-free synovial mesenchymal stem cell-derived tissue-engineered construct (TEC) for the cartilage layer, successfully repaired osteochondral defects in a rabbit model. To facilitate less invasive surgical application, the authors investigated alternative HA forms including granules and paste for use in the subchondral component for the biphasic implant.HYPOTHESISBiphasic implants composed of TEC combined with either HA granules or HA paste would potentially achieve successful osteochondral repair, comparable to that of a conventional HA block-based implant.STUDY DESIGNControlled laboratory study.METHODSBilateral osteochondral defects (5 mm in diameter and 6 mm in depth) were created in the femoral grooves of rabbits and treated with a TEC combined with 1 of 3 HA forms: block, granules, or paste. Histological and biomechanical analyses were performed at 4, 8, and 24 weeks postimplantation (5 per group per time point).RESULTSThe TEC/HA block group achieved complete osteochondral repair with stable maturation, and the repaired tissue demonstrated biomechanical properties comparable to native tissue at 24 weeks postimplantation. In contrast, the TEC/HA granule group showed early signs of repair that progressively deteriorated, resulting in significantly inferior structural and mechanical properties. The TEC/HA paste group supported subchondral bone repair but resulted in incomplete cartilage formation at 24 weeks postimplantation.CONCLUSIONThe TEC/HA block implant showed superior histological and biomechanical outcomes compared with other HA forms. Therefore, further optimization of granular or paste formulation is required to possibly enhance the potential for arthroscopic or minimally invasive delivery of a biphasic implant.CLINICAL RELEVANCEThis study highlights the potential of biphasic implants combining clinically available TEC and HA artificial bone for osteochondral repair. The biphasic implant can be easily prepared intraoperatively without specialized fabrication. Long-term observations revealed distinct repair patterns for each HA form, which may assist surgeons in selecting the optimal HA artificial bone form for effective and durable subchondral bone repair in osteochondral regeneration.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"275 1","pages":"3635465251407260"},"PeriodicalIF":0.0,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Simultaneous Bilateral, Staged Bilateral, and Unilateral Hip Arthroscopy for Femoroacetabular Impingement Syndrome: A Systematic Review and Meta-analysis. 同时双侧、分阶段双侧和单侧髋关节镜治疗股髋臼撞击综合征的结果:系统回顾和荟萃分析。
Pub Date : 2026-01-21 DOI: 10.1177/03635465251409347
Napatpong Thamrongskulsiri,Jacob T Morgan,Felipe Casanova,Tomas F Vega,Alireza Mirahmadi,Jorge Chahla
BACKGROUNDFemoroacetabular impingement (FAI) is a common cause of hip pain, often treated with arthroscopy. The optimal approach among unilateral, staged bilateral, and simultaneous bilateral procedures remains unclear due to limited comparative data.PURPOSETo compare clinical outcomes and complication rates among simultaneous bilateral, staged bilateral, and unilateral hip arthroscopy in patients with FAI syndrome.STUDY DESIGNSystematic review and Meta-analysis; Level of evidence, 3.METHODSA systematic review and meta-analysis were conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed, Scopus, and Ovid MEDLINE databases were searched through April 2025. Eligible comparative studies included patients with FAI undergoing hip arthroscopy via unilateral, simultaneous bilateral, or staged bilateral approaches and reported outcomes such as patient-reported scores, complications, and revision or conversion to total hip arthroplasty (THA).RESULTSNine studies with a total of 4040 hips were included. All surgical approaches showed significant improvements in pain and functional outcome scores. There were no statistically significant differences in postoperative visual analog scale score, Modified Harris Hip Score, Non-Arthritic Hip Score, International Hip Outcome Tool-12 score, rates of revision surgery, or conversion to THA among the 3 groups. Meta-analyses confirmed similar outcomes between staged and unilateral groups. Although 1 study reported a lower THA conversion rate in the simultaneous group, findings were inconsistent across the literature.CONCLUSIONSimultaneous bilateral, staged bilateral, and unilateral hip arthroscopy offer comparable short- to midterm outcomes and complication rates in FAI patients. Simultaneous bilateral arthroscopy may represent a safe and efficient option for appropriately selected patients. Surgical approaches should be individualized based on patient symptoms, goals, and risk profile.REGISTRATIONPROSPERO (CRD420251039957).
背景:股髋臼撞击(FAI)是髋关节疼痛的常见原因,通常通过关节镜治疗。由于有限的比较数据,单侧、分阶段双侧和同时双侧手术的最佳方法仍不清楚。目的比较FAI综合征患者同时双侧、分期双侧和单侧髋关节镜的临床结果和并发症发生率。研究设计:系统评价与meta分析;证据水平,3。方法按照PRISMA(首选系统评价和荟萃分析报告项目)指南进行系统评价和荟萃分析。检索PubMed、Scopus和Ovid MEDLINE数据库至2025年4月。符合条件的比较研究包括FAI患者通过单侧、同时双侧或分阶段双侧入路接受髋关节镜检查,并报告结果,如患者报告的评分、并发症、翻修或转换为全髋关节置换术(THA)。结果纳入9项研究,共4040例。所有手术入路的疼痛和功能评分均有显著改善。三组术后视觉模拟评分、改良Harris髋关节评分、非关节炎髋关节评分、国际髋关节结局工具-12评分、翻修手术率或THA转换率均无统计学差异。荟萃分析证实了分阶段组和单侧组的相似结果。虽然有一项研究报告了同期组THA转换率较低,但文献中的研究结果不一致。结论:同时双侧、分阶段双侧和单侧髋关节镜检查对FAI患者的短期和中期预后和并发症发生率具有可比性。同时双侧关节镜检查可能是一个安全有效的选择,适当选择的患者。手术入路应根据患者症状、目标和风险概况进行个体化治疗。REGISTRATIONPROSPERO (CRD420251039957)。
{"title":"Outcomes of Simultaneous Bilateral, Staged Bilateral, and Unilateral Hip Arthroscopy for Femoroacetabular Impingement Syndrome: A Systematic Review and Meta-analysis.","authors":"Napatpong Thamrongskulsiri,Jacob T Morgan,Felipe Casanova,Tomas F Vega,Alireza Mirahmadi,Jorge Chahla","doi":"10.1177/03635465251409347","DOIUrl":"https://doi.org/10.1177/03635465251409347","url":null,"abstract":"BACKGROUNDFemoroacetabular impingement (FAI) is a common cause of hip pain, often treated with arthroscopy. The optimal approach among unilateral, staged bilateral, and simultaneous bilateral procedures remains unclear due to limited comparative data.PURPOSETo compare clinical outcomes and complication rates among simultaneous bilateral, staged bilateral, and unilateral hip arthroscopy in patients with FAI syndrome.STUDY DESIGNSystematic review and Meta-analysis; Level of evidence, 3.METHODSA systematic review and meta-analysis were conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed, Scopus, and Ovid MEDLINE databases were searched through April 2025. Eligible comparative studies included patients with FAI undergoing hip arthroscopy via unilateral, simultaneous bilateral, or staged bilateral approaches and reported outcomes such as patient-reported scores, complications, and revision or conversion to total hip arthroplasty (THA).RESULTSNine studies with a total of 4040 hips were included. All surgical approaches showed significant improvements in pain and functional outcome scores. There were no statistically significant differences in postoperative visual analog scale score, Modified Harris Hip Score, Non-Arthritic Hip Score, International Hip Outcome Tool-12 score, rates of revision surgery, or conversion to THA among the 3 groups. Meta-analyses confirmed similar outcomes between staged and unilateral groups. Although 1 study reported a lower THA conversion rate in the simultaneous group, findings were inconsistent across the literature.CONCLUSIONSimultaneous bilateral, staged bilateral, and unilateral hip arthroscopy offer comparable short- to midterm outcomes and complication rates in FAI patients. Simultaneous bilateral arthroscopy may represent a safe and efficient option for appropriately selected patients. Surgical approaches should be individualized based on patient symptoms, goals, and risk profile.REGISTRATIONPROSPERO (CRD420251039957).","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"194 1","pages":"3635465251409347"},"PeriodicalIF":0.0,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arthroscopic Posterior Bankart Repair: Risk Factors for Recurrence of Instability. 关节镜下后Bankart修复:不稳定复发的危险因素。
Pub Date : 2026-01-21 DOI: 10.1177/03635465251403499
Valeria Vismara,Pascal Boileau
BACKGROUNDThe high rates of failures and reoperations (up to 50%) after arthroscopic posterior Bankart repair (APBR) remain a concern.PURPOSETo evaluate mid- to long-term follow-up outcomes of APBR in patients with unidirectional, recurrent posterior shoulder instability and to identify risk factors for failure.STUDY DESIGNCase series; Level of evidence, 4.METHODSA single-center, retrospective study was conducted that included all consecutive athletes with unidirectional recurrent posterior shoulder instability operated on between 2006 and 2022. Patients with voluntary instability or previous failed instability repair were excluded. The posterior labrum was reattached using a minimum of 4 suture anchors, and a posteroinferior capsular shift was systematically performed. The mean follow-up was 11 years (range, 2-18 years). At final follow-up, the investigators evaluated persistent pain, apprehension, recurrence of instability (recurrent episode of either true dislocation or subluxation), range of motion, return to sport, and satisfaction. Revision surgeries and reoperations were also recorded.RESULTSThe study included 44 athletes (45 shoulders). Patients were predominantly males (96%) and had a mean age of 28 years at surgery, and half (51%) practiced a contact or collision sport. Recurrence of posterior instability occurred in 22% (10/45): 2 patients sustained frank posterior dislocations, 6 reported recurrent subluxations, and 2 had a single episode of subluxation. Of the 10 patients with recurrence of instability, only 2 were reoperated (revision rate 4%); the 8 remaining patients declined any additional surgery. The presence of posterior glenoid bone erosion (9 patients) was associated with a higher risk of postoperative recurrent dislocation or subluxation (P = .024). By contrast, the presence of a posterior glenoid fracture (6 patients) was not a risk factor for postoperative recurrence of instability. Other potential prognostic factors (young age, contact sport, voluntary instability that became involuntary, or reproducible instability) were not found to be significant in the present series. At 1-year follow-up, 75% returned to the same level of sports.CONCLUSIONIn patients with recurrent posterior instability, the presence of posterior glenoid erosion was the main risk factor for failure after APBR. By contrast, a posterior bony Bankart lesion did not represent a contraindication to arthroscopic stabilization using suture anchor fixation.
背景:关节镜后路Bankart修复(APBR)后的高失败率和再手术率(高达50%)仍然是一个值得关注的问题。目的评价APBR治疗单向性复发性后肩不稳患者的中长期随访结果,并确定失败的危险因素。研究设计案例系列;证据等级,4级。方法采用单中心回顾性研究,纳入2006年至2022年间所有连续接受单向复发性后肩不稳手术的运动员。排除自愿不稳定或既往不稳定修复失败的患者。使用至少4个缝合锚将后唇重新连接,并系统地进行后下囊移位。平均随访11年(范围2-18年)。在最后的随访中,研究人员评估了持续疼痛、恐惧、不稳定复发(真正脱位或半脱位的复发)、活动范围、恢复运动和满意度。翻修手术和再手术也有记录。结果本研究纳入44名运动员(45肩)。患者主要为男性(96%),手术时平均年龄28岁,一半(51%)从事接触或碰撞运动。22%(10/45)的患者后路不稳复发:2例患者后路脱位,6例复发性半脱位,2例有单次半脱位。10例不稳定复发患者中,仅2例再次手术(翻修率4%);剩下的8名患者拒绝了任何额外的手术。后盂骨糜烂(9例)与术后复发性脱位或半脱位的高风险相关(P = 0.024)。相比之下,后盂骨折(6例)的存在并不是术后不稳定复发的危险因素。其他潜在的预后因素(年轻、接触性运动、自愿不稳定变为非自愿或可重复性不稳定)在本系列研究中未被发现有显著意义。在1年的随访中,75%的人恢复到相同的运动水平。结论复发性后关节不稳患者,后关节盂糜烂是APBR术后失败的主要危险因素。相比之下,后路骨Bankart病变不代表关节镜下使用缝合锚定固定的禁忌。
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The American Journal of Sports Medicine
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