Case Reports in Cardiology最新文献

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Left Atrial Myxoma Presenting as Lateral Medullary (Wallenberg's) Syndrome. 左房黏液瘤表现为外侧髓质(瓦伦堡氏)综合征。

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-11-11 eCollection Date: 2019-01-01 DOI: 10.1155/2019/5610213

Simran Gupta, Ricky Ayala, Aakash Desai, Viraj I Modi, Robert J Nardino

Myxomas are benign, primary tumors of the heart. Atrial myxomas can present with a variety of clinical features including dyspnea, orthopnea, pulmonary edema, and pulmonary or systemic emboli. Constitutional symptoms such as fever and weight loss may also be present. We report the case of a young female presenting with headache, facial numbness, and vertigo, who was found to have a posterolateral medullary stroke secondary to a large left atrial cardiac myxoma.

黏液瘤是良性的心脏原发肿瘤。心房黏液瘤可表现出多种临床特征，包括呼吸困难、直立呼吸、肺水肿和肺或全身栓塞。体质症状，如发烧和体重减轻也可能出现。我们报告的情况下，年轻的女性表现为头痛，面部麻木，眩晕，谁被发现有一个后外侧髓质中风继发于一个大的左心房心脏黏液瘤。

引用次数: 2

Ticagrelor-Induced Prolongation of the QTc Interval. 替格瑞洛诱导的QTc间期延长。

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-11-07 eCollection Date: 2019-01-01 DOI: 10.1155/2019/5984847

Avik Ray, Ahmad Najmi, Gaurav Khandelwal, Balakrishnan Sadasivam

Background: Ticagrelor has been accepted as a class I antiplatelet agent in patients undergoing percutaneous coronary angioplasty (PTCA). There have been cases reported on ticagrelor being associated with various cardiac conduction defects. But there is no evidence of QTc prolongation associated with the drug as of yet.

Case presentation: A 64-year-old male who underwent PTCA was given ticagrelor. A baseline electrocardiogram (ECG) showed a QTc of 402 ms. He returned after 1.5 months with complaints of shortness of breath. An ECG revealed a prolonged QTc of 468 ms. Ticagrelor was discontinued in view of ticagrelor-induced dyspnea and the patient was started on clopidogrel. The other medications were kept unchanged. The patient returned after a month without any complaints. A follow-up ECG showed a reduced QTc of 425 ms.

Conclusion: We present a case of ticagrelor-induced QTc prolongation. To our knowledge, this is the first case to be reported on the same. The Naranjo algorithm for causality assessment gave a total score of 6 indicating that the adverse drug reaction falls under the probable category.

背景:替格瑞洛已被接受为经皮冠状动脉成形术(PTCA)患者的I类抗血小板药物。有病例报道，替格瑞洛与各种心脏传导缺陷有关。但目前还没有证据表明QTc延长与该药有关。病例介绍:一位接受PTCA的64岁男性给予替格瑞洛。基线心电图(ECG)显示QTc为402 ms。1个半月后，他回到医院，主诉呼吸短促。心电图显示QTc延长468毫秒。考虑到替卡格雷引起的呼吸困难，停用替卡格雷，患者开始使用氯吡格雷。其他药物保持不变。一个月后病人回来了，没有任何不适。随访心电图显示QTc减少425 ms。结论:我们报告了一例替格瑞洛致QTc延长。据我们所知，这是在同一地点报告的首例病例。因果关系评估的Naranjo算法给出的总分为6分，表明该药物不良反应属于可能类别。

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引用次数: 3

An Incidental Diagnosis of Rheumatic Mitral Stenosis and Secundum Atrial Septal Defect (Lutembacher's Syndrome) in a Young Woman 一例年轻女性风湿性二尖瓣狭窄和第二房间隔缺损(Lutembacher综合征)的偶然诊断

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-10-30 DOI: 10.1155/2019/9402987

M. Alam, Md Fakhrul Islam Khaled

Lutembacher's syndrome is a rare cardiovascular defect comprising of mitral stenosis and atrial septal defect. A combination of acquired mitral stenosis and congenital atrial septal defect is the most well-recognized pattern. As atrial septal defect acts as a pressure relieving gateway, signs and symptoms of mitral stenosis may be attenuated and/or delayed in such patients. We have presented a case with Lutembacher's syndrome that was incidentally diagnosed as having such defect during outpatient check-up for upper respiratory infection.

Lutembacher综合征是一种罕见的心血管疾病，包括二尖瓣狭窄和房间隔缺损。获得性二尖瓣狭窄和先天性房间隔缺损的合并是最常见的模式。由于房间隔缺损作为减压通道，二尖瓣狭窄的体征和症状可能减轻和/或延迟。我们提出了一个病例与Lutembacher's综合征是偶然诊断为有这样的缺陷在门诊检查上呼吸道感染。

引用次数: 5

A Rare Case of Chylothorax after Heart Transplantation 心脏移植术后乳糜胸1例

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-10-21 DOI: 10.1155/2019/2049704

A. Alam, Linle Hou, D. James, K. Mody, D. Iyer, A. Ghaly, J. Almendral

Chylothorax is an exceedingly rare but serious complication of orthotopic heart transplantation (OHT). Prompt diagnosis and appropriate management are essential for a good outcome. Management is similar to that of nontransplant patients, but special attention must be given to patients' nutritional and immunological status. Relevant literature on this topic is limited. We describe our experience in the management of chylothorax after OHT and provide a summary of reported cases of this complication after isolated heart and combined heart/lung transplant.

乳糜胸是一种非常罕见但严重的原位心脏移植并发症。及时的诊断和适当的治疗是获得良好结果的必要条件。处理方法与非移植患者相似，但必须特别注意患者的营养和免疫状况。关于这个主题的相关文献是有限的。我们描述了我们在OHT后乳糜胸的处理经验，并提供了孤立心脏和心肺联合移植后乳糜胸并发症的报告病例摘要。

引用次数: 1

An Unusual Cause of Dyspnea and Thoracic Pressure 呼吸困难和胸压的不寻常原因

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-10-20 DOI: 10.1155/2019/2574858

Claire Chakkalakal, R. Jorbenadze, M. Gawaz

There is a high prevalence of hepatic cysts in the general population. Simple cysts are most of the times asymptomatic and are usually detected incidentally on ultrasonography, computed tomography, or magnetic resonance imaging. Symptoms may range from abdominal discomfort and pain, early satiety, dyspepsia, nausea, and vomiting to jaundice and portal hypertension due to obstruction of adjacent structures. Complications include spontaneous hemorrhage, infection, thrombosis, and atrophy of surrounding hepatic tissue. We present a unique case of a middle-aged patient with acute onset of dyspnea and thoracic pressure due to compression of the right ventricle by a large hepatic cyst.

肝囊肿在普通人群中的患病率很高。单纯囊肿大多数时候是无症状的，通常在超声、计算机断层扫描或磁共振成像中偶然发现。症状可能包括腹部不适和疼痛、早期饱腹感、消化不良、恶心和呕吐，以及由于邻近结构阻塞而引起的黄疸和门静脉高压。并发症包括自发性出血、感染、血栓形成和周围肝组织萎缩。我们报告了一个独特的病例，一名中年患者因大肝囊肿压迫右心室而急性发作呼吸困难和胸压。

引用次数: 2

Squamous Cell Carcinoma of the Tongue with Metastasis to Myocardium: Report of a Case and Literature Review 舌鳞状细胞癌向心肌转移1例报告并文献复习

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-10-17 DOI: 10.1155/2019/1649580

A. Shafiq, Fatima Samad, E. Roberts, J. Levin, U. Nawaz, A. Tajik

This is a case of a 43-year-old man who in 2014 was diagnosed with oral squamous cell carcinoma involving the tongue. He underwent extensive surgery that involved right tongue cancer resection and reconstruction with a free flap graft from his right forearm. He then was started on chemotherapy and radiation. Surveillance computed tomography in December 2016 showed a cardiac lesion in the left ventricular apex, which was confirmed by further echocardiography and cardiac magnetic resonance imaging. A biopsy of the mass revealed metastatic squamous cell carcinoma. He was deemed to not be a surgical candidate and continued on palliative chemotherapy. The patient had a very poor prognosis and eventually succumbed to the disease, highlighting the importance of surveillance imaging in such cases. A high index of suspicion on the part of the physician is needed to help in the early identification of these patients.

这是一名43岁男子的病例，他在2014年被诊断为涉及舌头的口腔鳞状细胞癌。他接受了广泛的手术，包括右舌癌症切除和右前臂游离皮瓣移植重建。然后他开始接受化疗和放射治疗。2016年12月的监测计算机断层扫描显示左心室心尖有心脏病变，进一步的超声心动图和心脏磁共振成像证实了这一点。活检发现转移性鳞状细胞癌。他被认为不是手术候选人，并继续进行姑息性化疗。该患者预后非常差，最终死于该疾病，这突出了监测成像在此类病例中的重要性。需要医生的高度怀疑指数来帮助早期识别这些患者。

引用次数: 8

Infective Aortic Valve Endocarditis Causing Embolic Consecutive ST-Elevation Myocardial Infarctions 感染性主动脉瓣心内膜炎致栓塞性ST段抬高心肌梗死

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-10-14 DOI: 10.1155/2019/2487616

Kanksha Peddi, A. Hsu, Tomas H Ayala

ST-elevation myocardial infarction (STEMI) is a rare and potentially fatal complication of infective endocarditis. We report the ninth case of embolic native aortic valve infective endocarditis causing STEMI and the first case to describe consecutive embolisms leading to infarctions of separate coronary territories. Through examination of this case in the context of the previous eight similar documented cases in the past, we find that infective endocarditis of the aortic valve can and frequently affect more than a single myocardial territory and can occur consecutively. Further, current treatment modalities for embolic infective endocarditis causing acute myocardial infarction are limited and unproven. This index case illustrates the potential severity of complications and the challenges in developing standardized management for such patients.

st段抬高型心肌梗死(STEMI)是感染性心内膜炎的一种罕见且可能致命的并发症。我们报告了第9例栓塞性原生主动脉瓣感染性心内膜炎引起STEMI和第一例描述连续栓塞导致单独冠状动脉区域梗死的病例。通过对该病例的检查，我们发现主动脉瓣的感染性心内膜炎可以并且经常影响不止一个心肌区域，并且可以连续发生。此外，目前栓塞性感染性心内膜炎引起急性心肌梗死的治疗方式是有限的和未经证实的。这个病例说明了并发症的潜在严重性和为这类患者制定标准化管理的挑战。

引用次数: 2

QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide. 三氧化二砷诱发的QT独立性室性心动过速。

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-10-13 eCollection Date: 2019-01-01 DOI: 10.1155/2019/9870283

Vicken Zeitjian, Carmel Moazez, Waqas Arslan, Mehrdad Saririan

Arsenic trioxide (ATO) is commonly known to cause QT prolongation with resultant ventricular tachycardia (VT). VT, independent of QT prolongation, can be a complication of ATO. We present a 46-year-old female who received ATO and during her hospital course had intermittent nonsustained VT. All usual causes of VT were considered including reduced EF < 35%, ischemia, electrolyte abnormalities, medications, and genetic polymorphisms; however, no specific cause was found. After stopping therapy, the episodes of nonsustained VT ceased indicating that there is an association between ATO and VT.

三氧化二砷（ATO）通常会导致QT延长并导致室性心动过速（VT）。室性心动过速与QT延长无关，可能是ATO的并发症。我们报告了一名46岁的女性，她接受了ATO治疗，在住院期间出现间歇性非持续性室性心动过速。考虑了室性心动过速的所有常见原因，包括EF降低<35%、缺血、电解质异常、药物和遗传多态性；然而，没有发现具体的原因。停止治疗后，非持续性室性心动过速发作停止，表明ATO和室性心动过速之间存在关联。

引用次数: 1

A Rare Complication of HVAD Outflow Thrombosis and the Importance of HVAD Waveform Analysis HVAD流出血栓形成的罕见并发症及HVAD波形分析的重要性

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-10-13 DOI: 10.1155/2019/6905397

J. Ning, N. Gaglianello

We present a case of a 64-year-old female who was supported with an HVAD as bridge-to-transplant (BTT) who presented with a gastrointestinal (GI) bleeding and underwent esophagogastroduodenoscopy (EGD) and colonoscopy. Her waveforms changed abruptly following the procedure, and she decompensated. With various imaging modalities and hemodynamic monitoring, we felt that she had thrombus in her outflow graft, which improved following systemic heparinization. She was listed for cardiac transplantation and remained hospitalized. At the time of surgery, her outflow graft was noted to be compressed externally and pathology was consistent with platelet-fibrin thrombus deposition.

我们报告了一例64岁女性患者，她接受了HVAD作为移植桥(BTT)，她表现为胃肠道(GI)出血，并接受了食管胃十二指肠镜(EGD)和结肠镜检查。手术后她的波形突然改变，她失去了代偿能力。通过各种成像方式和血流动力学监测，我们认为她的流出静脉移植物有血栓，在全身肝素化治疗后有所改善。她被列入心脏移植名单，并一直住院。在手术时，她的流出移植物被注意到外压，病理符合血小板-纤维蛋白血栓沉积。

引用次数: 0

Profound Iron Deficiency Anemia and Irreversible Dilated Cardiomyopathy in a Child 儿童深部缺铁性贫血与不可逆性扩张型心肌病

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Case Reports in Cardiology

Pub Date : 2019-10-10 DOI: 10.1155/2019/7513782

S. Wittekind, Hugo R Martinez, C. Villa, M. Bacon, A. Hammill, A. Lorts

Iron deficiency anemia has been associated with a secondary and potentially reversible cardiomyopathy. The pathophysiologic paradigm has been that the hematologic disease begets cardiac dysfunction. There may be, however, a point at which myocardial injury is irreversible in susceptible individuals. We present the case of a 4-year-old, developmentally normal, child who presented with iron deficiency anemia and a dilated cardiomyopathy with congestive heart failure. Despite appropriate correction of the anemia, the patient developed decompensated heart failure requiring milrinone therapy and eventual heart transplantation. This report will alert clinicians to the potential for irreversible adverse cardiac remodeling and the importance of close pediatric cardiology consultation and serial assessment in order to implement appropriate heart failure therapy.

缺铁性贫血与继发性和潜在可逆的心肌病有关。病理生理学范式一直是血液病导致心功能障碍。然而，在易感个体中，心肌损伤可能达到不可逆转的程度。我们提出的情况下，一个4岁，发育正常，儿童谁提出了缺铁性贫血和扩张性心肌病与充血性心力衰竭。尽管对贫血进行了适当的纠正，但患者出现代偿性心力衰竭，需要米力农治疗和最终的心脏移植。本报告将提醒临床医生注意不可逆转的不良心脏重构的可能性，以及密切儿科心脏病学咨询和系列评估的重要性，以便实施适当的心力衰竭治疗。

引用次数: 4

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