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Heart Failure in a Young Adult with a Fine-Lubinsky Syndrome: An Unknown Comorbidity 患有 Fine-Lubinsky 综合征的年轻成人的心力衰竭:一种未知的并发症
IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-01-02 DOI: 10.1155/2024/5596010
Blake Purtle, Jason Wagner, Andrew Zarker, Vishal Patel, David Aguilar
The Fine-Lubinsky syndrome (FLS) is a rare congenital disorder. Heart failure has not been described in young adults with this condition. Here, we report the first case of heart failure in a young adult patient with FLS. This finding highlights the need for further investigation into cardiac complications in this illness.
Fine-Lubinsky 综合征(FLS)是一种罕见的先天性疾病。在患有这种疾病的青壮年患者中,还没有出现过心力衰竭的病例。在此,我们报告了首例患有 FLS 的年轻成人患者的心力衰竭病例。这一发现凸显了进一步研究该病心脏并发症的必要性。
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引用次数: 0
Pacemaker Lead Entanglement during Interventional PFO Occlusion: Salvage Using a Sizing Balloon. 介入性 PFO 闭塞时起搏器导线缠绕:使用定径球囊进行抢救
IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-12-13 eCollection Date: 2023-01-01 DOI: 10.1155/2023/5586197
Andreas Goldschmied, Juergen Schreieck, Michal Droppa

We present a case of a patient with a transient ischaemic attack (TIA) likely due to paradoxical embolism through a patent foramen ovale (PFO). Her medical history included 2nd-degree heart block Mobitz II, which manifested with recurrent syncopes and was treated with a dual chamber pacemaker. During the interventional PFO closure procedure, we noted entrapment of the atrial pacemaker lead between the right-sided occluder disc and the interatrial septum. We were able to successfully move the lead aside using a 24 mm sizing balloon and subsequently developed the right-sided occluder disc in the correct position. In conclusion, pacemaker-lead entrapment between a PFO occluder disc and the interatrial septum can be prevented using a sizing balloon.

我们为您介绍一例可能因卵圆孔栓塞(PFO)引起的短暂性缺血性发作(TIA)患者。她的病史包括二度心脏传导阻滞 Mobitz II,表现为反复晕厥,曾接受双腔起搏器治疗。在 PFO 介入封堵术中,我们注意到心房起搏器导线被夹在右侧封堵器圆盘和房间隔之间。我们使用一个 24 毫米大小的球囊成功地将导联移至一侧,随后将右侧封堵器盘开发到正确位置。总之,使用尺寸调整球囊可以防止起搏器导联夹在 PFO 闭塞盘和房间隔之间。
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引用次数: 0
Recurrent Biatrial Myxomas in Carney Complex with a Spinal Melanotic Schwannoma: Advocacy for a Rigorous Multidisciplinary Follow-Up. 患有脊髓黑色素性许旺瘤的卡尼复合体复发性双房肌瘤:倡导严格的多学科随访。
IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-12-11 eCollection Date: 2023-01-01 DOI: 10.1155/2023/7896180
Daniel Grandmougin, Teresa Moussu, Maxime Hubert, Benjamin Perin, Arthur Huber, Maria Christina Delolme, Juan-Pablo Maureira

A 31-year-old female patient with a previous history of Carney complex and surgical resection for cardiac myxoma and bilateral adrenalectomy at 18 years old and 10 and 11 years old, respectively, was referred to our department with a diagnosis of recurrent biatrial myxomas incidentally discovered on echography. A magnetic resonance imaging (MRI) confirmed the diagnosis of a tumor protruding into the left ventricle, and the patient underwent a surgical resection of a large left atrial mass and a right-sided atrial small tumor. Diagnosis of bilateral atrial myxomas was confirmed by histologic studies. Postoperative outcome was uneventful, and the patient was discharged at the 7th postoperative day. Few months later, she reported trivial clinical symptoms suspecting a cervical radiculopathy. MRI confirmed the presence of a compressive cervical spinal cord tumoral mass at the C2-3 level leading to perform a surgical exeresis of the tumor. Histology showed a spinal melanotic schwannoma. This case highlights the risk of unexpected ubiquitary tumor locations and the importance of a rigorous transversal multidisciplinary follow-up to prevent severe complications in patients with Carney complex.

一名31岁的女性患者曾患有卡尼综合征,并分别于18岁和10岁及11岁时因心脏肌瘤和双侧肾上腺切除术而接受过手术切除,因回声检查时偶然发现复发性双心房肌瘤而转诊至我科。磁共振成像(MRI)确诊肿瘤突入左心室,患者接受了左心房大肿块和右心房小肿瘤的手术切除。组织学研究证实了双侧心房肌瘤的诊断。术后恢复顺利,患者于术后第 7 天出院。几个月后,她出现了轻微的临床症状,怀疑是颈椎病。核磁共振成像证实,C2-3水平存在压迫性颈椎脊髓肿瘤肿块,因此对肿瘤进行了手术切除。组织学检查显示该肿瘤为脊髓黑色素分裂瘤。该病例突出表明了意外的泛发性肿瘤位置的风险,以及对卡尼综合征患者进行严格的横向多学科随访以预防严重并发症的重要性。
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引用次数: 0
An Unusual Presentation of Streptococcus gallolyticus in Infective Endocarditis. 感染性心内膜炎胆溶血性链球菌的异常表现
IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-11-30 eCollection Date: 2023-01-01 DOI: 10.1155/2023/9948719
Laura Torres Cruz, Maryam Barkhordarian, Neenu Antony, Muhammad Yasir, Sai Priyanka Pulipaka, Ahmad Al-Awwa, Sameh Elias

Background. Streptococcus gallolyticus (previously known as Streptococcus bovis type-1) bacteremia has a well-established, almost pathognomonic association with colorectal carcinoma, with the most common hypothesized mechanism being ulceration of polyps leading to hematologic dissemination. There are few reported cases of streptococcus bacteremia from other, seemingly benign sources like cellulitis or colonic adenomas. Hence, there is limited focus on skin and soft tissue infections leading to potentially fatal infective endocarditis. Case Presentation. We present a novel case of streptococcus bacteremia from uncommon sources like abdominal wall cellulitis or colonic adenoma leading to infective endocarditis as well as other manifestations, including osteomyelitis and discitis. This report highlights a unique case of streptococcus bacteremia with an uncommon origin, arising from abdominal wall cellulitis or colonic adenoma, ultimately resulting in the development of infective endocarditis. Furthermore, the patient presented with additional clinical manifestations, including osteomyelitis and discitis. Conclusions. Through our case report, we emphasize the importance of investigating uncommon sources like cellulitis when initial malignant workup is negative in streptococcus bacteremia and further elucidate the pathophysiology of streptococcus bacterial dissemination from nonmalignancy-related sources.

背景。胆溶血性链球菌(以前称为 1 型牛型链球菌)菌血症与结肠直肠癌有着公认的、几乎是同病相怜的联系,最常见的假设机制是息肉溃疡导致血液传播。其他看似良性的来源(如蜂窝组织炎或结肠腺瘤)引起链球菌菌血症的病例报道很少。因此,人们对皮肤和软组织感染导致潜在致命的感染性心内膜炎的关注有限。病例介绍。我们介绍了一例由腹壁蜂窝织炎或结肠腺瘤等不常见来源导致感染性心内膜炎及其他表现(包括骨髓炎和椎间盘炎)的链球菌菌血症新病例。本报告重点介绍了一例独特的链球菌菌血症病例,其病因并不常见,是腹壁蜂窝织炎或结肠腺瘤,最终导致感染性心内膜炎的发生。此外,患者还伴有骨髓炎和椎间盘炎等其他临床表现。结论。通过我们的病例报告,我们强调了当链球菌菌血症的初始恶性检查结果为阴性时,调查蜂窝组织炎等不常见来源的重要性,并进一步阐明了非恶性肿瘤相关来源的链球菌细菌传播的病理生理学。
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引用次数: 0
IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion. 积液诊断igg4相关性心包炎。
IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-11-24 eCollection Date: 2023-01-01 DOI: 10.1155/2023/9223342
Hirohito Sugawara, Tomokazu Takahashi, Yukishige Kimura, Azumi Matsui, Tamaki Matsumoto, Kimio Nishisato, Mitsuhiro Nishimura

IgG4-related pericarditis has rarely been reported. Here, we report a case of IgG4-related disease that presented with pericardial effusion. A 67-year-old female who presented with palpitations and chest pain was admitted because of a large amount of pericardial effusion that required drainage. The patient underwent pericardial drainage, and the symptoms were gradually alleviated. IgG4 levels were elevated in the serum and pericardial effusions. A biopsy specimen of 18F-FDG accumulated in the submandibular gland showed lymphocyte infiltration with IgG4-positive cells. The patient was diagnosed with IgG4-related pericarditis. Glucocorticoids resolved serological and imaging abnormalities. Prompt treatment improves the disease status.

igg4相关的心包炎很少有报道。在此,我们报告一例以心包积液表现的igg4相关疾病。一位67岁女性,因大量心包积液需要引流而入院,她表现为心悸和胸痛。患者行心包引流,症状逐渐缓解。血清和心包积液中IgG4水平升高。在颌下腺积累的18F-FDG活检标本显示淋巴细胞浸润igg4阳性细胞。患者被诊断为igg4相关性心包炎。糖皮质激素解决血清学和影像学异常。及时治疗可改善病情。
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引用次数: 0
Aortic Pseudoaneurysm following Ventricular Septal Defect Closure in a Pediatric Patient: A Case Report and Literature Review. 小儿室间隔缺损闭合后主动脉假性动脉瘤1例报告及文献回顾。
IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-11-23 eCollection Date: 2023-01-01 DOI: 10.1155/2023/2890844
Hassan Zamani, Kourosh Vahidshahi, Mohammad Reza Khalilian, Tahmineh Tahouri, Ehsanollah Rahimi-Movaghar

Aortic pseudoaneurysm, a rare condition characterized by localized transmural disruption and dilatation of the aorta, is very rare in the pediatric population. It is primarily caused by previous cardiovascular procedures such as aortic coarctation repair, aortic valve replacement, and subaortic membrane resection. We present a unique case of aortic pseudoaneurysm following surgery to repair a perimembranous ventricular septal defect in a 19-month-old boy who presented with fever as the sole symptom. The fever started on the 30th day after the surgery, and the patient exhibited abnormal laboratory results, including a white blood cell (WBC) count of 28.3 × 109/L, neutrophil percentage of 68%, platelet count of 880 × 109/L, erythrocyte sedimentation rate (ESR) of 200 mm/hour, and 3+ positive C-reactive protein. Echocardiogram revealed a large cystic mass (5 × 4.8 cm) in the ascending aorta, compressing the superior vena cava. Based on this finding, a diagnosis of aortic pseudoaneurysm was suspected. The diagnosis was confirmed through cardiac computed tomographic angiography, and the patient underwent emergent surgery for the repair of the aortic pseudoaneurysm under deep hypothermia and circulatory arrest. Unfortunately, our patient died shortly after the surgery.

主动脉假性动脉瘤是一种罕见的疾病,其特征是局部的跨壁破坏和主动脉扩张,在儿科人群中非常罕见。它主要是由先前的心血管手术引起的,如主动脉缩窄修复、主动脉瓣置换术和主动脉下膜切除术。我们提出一个独特的病例主动脉假性动脉瘤手术后修复膜周围室间隔缺损在一个19个月大的男孩谁提出发烧作为唯一的症状。术后第30天开始发热,实验室检查结果异常,白细胞(WBC) 28.3 × 109/L,中性粒细胞百分比68%,血小板计数880 × 109/L,红细胞沉降率(ESR) 200 mm/h, c反应蛋白3+阳性。超声心动图示升主动脉内一巨大囊性肿块(5 × 4.8 cm),压迫上腔静脉。基于这一发现,我们怀疑诊断为主动脉假性动脉瘤。经心脏计算机断层血管造影确诊,患者在深低温和循环停止下接受紧急手术修复主动脉假性动脉瘤。不幸的是,我们的病人在手术后不久就死了。
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引用次数: 0
To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis. 胺碘酮性甲状腺毒症是否应用PLEX。
IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-11-20 eCollection Date: 2023-01-01 DOI: 10.1155/2023/1563732
Tania Ahuja, Olivia Nuti, Cameron Kemal, Darren Kang, Eugene Yuriditsky, James M Horowitz, Raymond A Pashun

Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as "PLEX" may help remove thyroid hormones and amiodarone. We report a case of PLEX in an attempt to treat cardiogenic shock secondary to AIT. This case highlights the robust rapidly deleterious demise of AIT, specifically in patients with decompensated heart failure. The decision to PLEX or not to PLEX for AIT should be individualized, prior to definitive therapy.

胺碘酮性甲状腺毒症(AIT)具有显著的心血管发病率。有两种类型的AIT治疗包括抗甲状腺药物和皮质类固醇和室性心律失常的治疗。治疗性血浆置换(TPE)也被称为“PLEX”,可能有助于去除甲状腺激素和胺碘酮。我们报告一例试图治疗继发于AIT的心源性休克的PLEX病例。本病例强调了AIT的强大、迅速、有害的死亡,特别是失代偿性心力衰竭患者。在确定治疗之前,对AIT进行PLEX或不进行PLEX的决定应个体化。
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引用次数: 0
Proper Treatment and Management of Postcardiotomy Refractory Vasospasm 切开术后难治性血管痉挛的正确治疗和处理
Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-11-10 DOI: 10.1155/2023/9988680
Caleb R. Weissman, Stephane Leung Wai Sang
We present here a unique case in which a 63-year-old man developed diffuse coronary vasospasm on postoperative day (POD) 1 following uneventful aortic valve replacement, replacement of ascending aorta, and coronary artery bypass. Subsequent emergent coronary angiogram demonstrated diffuse native coronary artery vasospasm that was only transiently responsive to intracardiac nitroglycerin, resulting in persistent cardiogenic shock and severe biventricular dysfunction. The patient was, thus, placed on femoral-femoral venoarterial (VA) extracorporeal membrane oxygenation (ECMO) with Impella support. This strategy allowed the weaning of vasopressors and enabled the resolution of the vasospasm. The patient was ultimately discharged on POD 17 without further complications. This case demonstrates our management strategy to provide life-saving support for patients facing postcardiac surgery refractory vasospasm.
我们在此报告一个独特的病例,其中一名63岁的男性在术后第一天(POD)进行了顺利的主动脉瓣置换术、升主动脉置换术和冠状动脉搭桥术后出现弥漫性冠状动脉痉挛。随后急诊冠状动脉造影显示弥漫性原生冠状动脉血管痉挛,仅对心内硝酸甘油有短暂反应,导致持续心源性休克和严重的双室功能障碍。因此,患者在Impella支持下进行股动脉(VA)体外膜氧合(ECMO)。该策略允许停用血管加压药物,并使血管痉挛得以解决。患者最终于POD 17出院,无进一步并发症。本病例展示了我们的管理策略,为心脏手术后难治性血管痉挛患者提供挽救生命的支持。
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引用次数: 0
Left Juxtaposition of the Right Atrial Appendage: Pitfalls in Diagnosis 右心耳左并置:诊断中的陷阱
Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-11-09 DOI: 10.1155/2023/1385305
Kanya Singhapakdi, Wesam Sourour, Thomas R. Kimball
Several congenital anomalies of the right atrial appendage (RAA) have been described including aneurysm, herniation (in association with a pericardial defect), and left juxtaposition. The left juxtaposition of the RAA (LJRAA), first described by Birmingham in 1893 and subsequently introduced by Dixon in 1954, is usually associated with complex cardiac malformations such as obstruction of the left ventricular outflow tract. In this case report, we will describe an unusual variant of LJRAA in the absence of any other cardiac defects, which was initially misinterpreted as an aortic dissection. The correct diagnosis was made after careful reinterpretation and the use of multiple imaging modalities as highlighted.
一些先天性右心耳异常(RAA)已被描述,包括动脉瘤、疝(与心包缺损相关)和左心耳并置。RAA左并置(LJRAA),由Birmingham于1893年首次描述,随后由Dixon于1954年引入,通常与复杂的心脏畸形有关,如左心室流出道梗阻。在这个病例报告中,我们将描述一个不寻常的LJRAA变异,在没有任何其他心脏缺陷的情况下,最初被误解为主动脉夹层。正确的诊断是在仔细的重新解释和使用多种成像方式后做出的。
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引用次数: 0
Uremic Pericarditis with Cardiac Tamponade in a Patient on Hemodialysis. 血液透析患者尿毒症心包炎合并心包填塞1例。
IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-11-06 eCollection Date: 2023-01-01 DOI: 10.1155/2023/5099005
Nismat Javed, Marcos Molina, Rabih Nasr, Gilda Diaz-Fuentes

Uremic pericardial effusion and pericarditis in end-stage kidney disease patients remain one of the causes responsible for high rates of morbidity and occasional mortality. While clinical presentation could be variable, clinicians should have a high index of suspicion for uremic pericarditis especially in patients who miss their dialysis sessions. We present a 77-year-old man with end-stage renal disease on dialysis diagnosed with pericarditis and large pericardial effusion complicated by cardiac tamponade and shock. He underwent urgent pericardiocentesis with clinical improvement. The course of the disease can be complicated by shock with multiorgan failure, particularly the liver. The presentation is relatively acute requiring a high level of suspicion, urgent diagnosis, and management to reduce mortality. As the geriatric population increases with associated comorbid conditions, it would be expected that patients undergoing dialysis would increase. Given the uncommon nature of the disease and how these patients have been managed by multiple specialties and care providers, it is important to consider dialysis-related complications in all patients with end-stage renal disease presenting with dyspnea.

终末期肾病患者的尿毒症性心包积液和心包炎仍然是造成高发病率和偶尔死亡率的原因之一。虽然临床表现可能是可变的,但临床医生应该高度怀疑尿毒症心包炎,特别是那些错过透析疗程的患者。我们报告一个77岁的终末期肾脏疾病的透析诊断为心包炎和大量心包积液并发心脏填塞和休克。他接受了紧急心包穿刺术,临床情况有所改善。该疾病的病程可因休克和多器官衰竭而复杂化,尤其是肝脏。表现是相对急性的,需要高度的怀疑,紧急诊断和管理,以减少死亡率。随着老年人口的增加和相关的合并症,预计接受透析的患者将会增加。鉴于这种疾病的不寻常性质以及这些患者是如何由多个专科和护理提供者管理的,考虑所有以呼吸困难为表现的终末期肾病患者的透析相关并发症是很重要的。
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引用次数: 0
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Case Reports in Cardiology
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