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Eritromelalgia como manifestación paraneoplásica de cáncer de colon. Reporte de caso 红斑肌痛是结肠癌的副肿瘤表现。案例报告
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.04.012
B.J. Flores Robles, J.A. López-Martín
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引用次数: 0
Factores asociados con mortalidad en mujeres con cirrosis descompensada alcohólica 与酒精性肝硬化妇女死亡率相关的因素
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.04.008
J.L. Pérez-Hernández , A.D. Santana-Vargas , G. Gutiérrez-Reyes , A. Díaz-Castro , E.J. Morales-Mairena , J.E. Lira-Vera , O. Morales-Gutiérrez , L.S. Juárez Chávez , M.F. Higuera-de-la-Tijera

Introduction and aims

Alcohol-related liver disease is becoming more common worldwide. Recently, alcohol consumption in women has increased significantly, raising the risk of developing alcohol-associated hepatitis, cirrhosis, and hepatocellular carcinoma. Greater susceptibility to alcohol-related liver damage appears to confer a higher mortality and decompensation risk on women. Our study aimed to assess alcohol consumption patterns and mortality rates in female patients with alcohol-related cirrhosis.

Material and methods

We conducted a single-center retrospective cohort study of patients hospitalized for cirrhosis due to chronic alcohol consumption at the Hospital General de Mexico «Dr. Eduardo Liceaga» between 2018 and 2021. Utilizing the patients’ electronic medical records, alcohol consumption patterns were identified and the survival rate for women and men after their first hospitalization was calculated through the Kaplan-Meier curve.

Results

A final total of 192 electronic medical records (50% women) were included. We classified the patients according to alcohol consumption into a) excessive consumption, or b) binge drinking. The median age for the onset of chronic alcohol consumption was higher in women than in men (18 vs. 16.5 years of age; P = 0.0001). The median for alcohol consumption in g/occasion was lower in women than in men (140 vs. 275 in excessive alcohol consumption and 196 vs 320 in binge drinking; P = 0.0001), as was the length of time of chronic alcohol consumption (24.5 vs. 30 years; P = 0.0001)
The mortality rate during the first hospitalization was 32.8% (61.9% for women and 38.9% for men). The mean age for survival was lower for women (33.8 ± 1.6 years of age, 95% CI: 30.5-37.1), compared with men (37.0 ± 1.2 years of age, 95% CI: 35.4-38.6) (P = .002). The factors associated with mortality in the Cox proportional hazards models were women vs men (OR = 4.1, 95% CI: 2.1-7.9) and excessive consumption vs binge drinking (OR = 1.9, 95% CI: 1.1-3.5).

Conclusions

Alcohol-related mortality is higher in women than in men and is associated with lower alcohol consumption, a shorter period of continued chronic consumption, and an older age at consumption onset.
酒精相关肝脏疾病在世界范围内变得越来越普遍。最近,女性饮酒量显著增加,增加了患酒精相关肝炎、肝硬化和肝细胞癌的风险。更容易受到酒精相关的肝损伤似乎会给女性带来更高的死亡率和代偿失偿风险。我们的研究旨在评估酒精相关性肝硬化女性患者的饮酒模式和死亡率。材料和方法我们在墨西哥总医院进行了一项单中心回顾性队列研究,研究对象是因慢性饮酒而住院的肝硬化患者。Eduardo Liceaga»,2018年至2021年。利用患者的电子医疗记录,确定了饮酒模式,并通过Kaplan-Meier曲线计算了首次住院后女性和男性的生存率。结果最终共纳入192份电子病历,其中女性占50%。我们根据饮酒量将患者分为a)过度饮酒和b)酗酒。女性慢性饮酒发病的中位年龄高于男性(18岁vs. 16.5岁;P = 0.0001)。女性每g/场合的饮酒量中位数低于男性(过量饮酒140 g对275 g,酗酒196 g对320 g, P = 0.0001),慢性饮酒时间长度也低于男性(24.5年对30年,P = 0.0001)。首次住院期间的死亡率为32.8%(女性61.9%,男性38.9%)。女性的平均生存年龄(33.8±1.6岁,95% CI: 30.5-37.1)低于男性(37.0±1.2岁,95% CI: 35.4-38.6) (P = 0.002)。在Cox比例风险模型中,与死亡率相关的因素是女性vs男性(OR = 4.1, 95% CI: 2.1-7.9)和过度消费vs酗酒(OR = 1.9, 95% CI: 1.1-3.5)。结论:女性与酒精相关的死亡率高于男性,且与饮酒量较低、持续慢性饮酒量较短以及开始饮酒时年龄较大有关。
{"title":"Factores asociados con mortalidad en mujeres con cirrosis descompensada alcohólica","authors":"J.L. Pérez-Hernández ,&nbsp;A.D. Santana-Vargas ,&nbsp;G. Gutiérrez-Reyes ,&nbsp;A. Díaz-Castro ,&nbsp;E.J. Morales-Mairena ,&nbsp;J.E. Lira-Vera ,&nbsp;O. Morales-Gutiérrez ,&nbsp;L.S. Juárez Chávez ,&nbsp;M.F. Higuera-de-la-Tijera","doi":"10.1016/j.rgmx.2025.04.008","DOIUrl":"10.1016/j.rgmx.2025.04.008","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Alcohol-related liver disease is becoming more common worldwide. Recently, alcohol consumption in women has increased significantly, raising the risk of developing alcohol-associated hepatitis, cirrhosis, and hepatocellular carcinoma. Greater susceptibility to alcohol-related liver damage appears to confer a higher mortality and decompensation risk on women. Our study aimed to assess alcohol consumption patterns and mortality rates in female patients with alcohol-related cirrhosis.</div></div><div><h3>Material and methods</h3><div>We conducted a single-center retrospective cohort study of patients hospitalized for cirrhosis due to chronic alcohol consumption at the Hospital General de Mexico «Dr. Eduardo Liceaga» between 2018 and 2021. Utilizing the patients’ electronic medical records, alcohol consumption patterns were identified and the survival rate for women and men after their first hospitalization was calculated through the Kaplan-Meier curve.</div></div><div><h3>Results</h3><div>A final total of 192 electronic medical records (50% women) were included. We classified the patients according to alcohol consumption into a)<!--> <!-->excessive consumption, or b)<!--> <!-->binge drinking. The median age for the onset of chronic alcohol consumption was higher in women than in men (18 vs. 16.5 years of age; P<!--> <!-->=<!--> <!-->0.0001). The median for alcohol consumption in g/occasion was lower in women than in men (140 vs. 275 in excessive alcohol consumption and 196 vs 320 in binge drinking; P<!--> <!-->=<!--> <!-->0.0001), as was the length of time of chronic alcohol consumption (24.5 vs. 30 years; P<!--> <!-->=<!--> <!-->0.0001)</div><div>The mortality rate during the first hospitalization was 32.8% (61.9% for women and 38.9% for men). The mean age for survival was lower for women (33.8<!--> <!-->±<!--> <!-->1.6 years of age, 95%<!--> <!-->CI: 30.5-37.1), compared with men (37.0<!--> <!-->±<!--> <!-->1.2 years of age, 95%<!--> <!-->CI: 35.4-38.6) (<em>P</em> <!-->=<!--> <!-->.002). The factors associated with mortality in the Cox proportional hazards models were women vs men (OR<!--> <!-->=<!--> <!-->4.1, 95%<!--> <!-->CI: 2.1-7.9) and excessive consumption vs binge drinking (OR<!--> <!-->=<!--> <!-->1.9, 95%<!--> <!-->CI: 1.1-3.5).</div></div><div><h3>Conclusions</h3><div>Alcohol-related mortality is higher in women than in men and is associated with lower alcohol consumption, a shorter period of continued chronic consumption, and an older age at consumption onset.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"90 4","pages":"Pages 512-519"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Encuesta en gastroenterólogos latinoamericanos expertos en trastornos del eje intestino-cerebro sobre el diagnóstico y el tratamiento del síndrome de intestino irritable en la práctica clínica 对拉丁美洲肠-脑轴疾病专家的肠易激综合征临床诊断和治疗调查
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.03.005
I. Hanna-Jairala , G.A. Puentes-Leal , A.M. Madrid , L. Aguilar-Paiz , J. Suazo-Barahona , J.M. Remes-Troche , E. Coss-Adame , L.M. Bustos-Fernández , L. Solé , M. Gudiño-Zayas , M. Schmulson

Introduction and aim

Even though the guidelines on irritable bowel syndrome (IBS) are similar worldwide, there are differences between countries that can influence management. Our aim was to evaluate the heterogeneity in IBS management in Latin America.

Materials and methods

An internet survey was applied to 97 gastroenterologists, specialists in disorders of gut-brain interaction (DGBI), from 14 Latin American countries, and included 111 questions: 23 on diagnosis and 88 on treatment. An exploratory, descriptive, observational analysis was carried out on general qualitative data, by IBS subtype and by country.

Results

Diagnostic data: 98% of those surveyed utilize the Rome IV criteria; 100% order laboratory tests when there are alarm symptoms; 90% order colonoscopy in patients over 50 years of age; 73% order abdominopelvic CT; 66% order breath tests for SIBO; and 96% order anorectal manometry in IBS-C with symptoms of a defecation disorder. Treatment data: antispasmodics are the most widely prescribed drugs, with differences according to IBS subtype and local availability; 83% indicate a low FODMAP diet; in IBS-D and abdominal distension, more than 90% prescribe rifaximin and/or probiotics, and 81%, cholestyramine; in IBS-C, the most widely prescribed treatments are polyethylene glycol, psyllium, prucalopride, and linaclotide; up to 94% indicate neuromodulators as second-line treatment; and 99% consider indicating psychotherapy in cases of depression.

Conclusions

Even though most of the specialists diagnose and treat IBS in accordance with guidelines, there are differences regarding local availability, and abdominopelvic CT appears to be overused. Knowing how general practitioners and internists manage this entity would be useful for establishing practical guidelines on the diagnosis and treatment of IBS that are adjusted by country.
前言和目的尽管世界范围内关于肠易激综合征(IBS)的指导方针是相似的,但不同国家之间的差异可能会影响管理。我们的目的是评估拉丁美洲肠易激综合征管理的异质性。材料和方法对来自14个拉丁美洲国家的97名胃肠病学家、肠脑相互作用紊乱(DGBI)专家进行了网络调查,包括111个问题:23个关于诊断,88个关于治疗。对IBS亚型和国家的一般定性数据进行了探索性、描述性和观察性分析。结果诊断数据:98%的被调查者使用Rome IV标准;当出现报警症状时,100%安排实验室检查;超过50岁的患者90%接受结肠镜检查;73%目骨盆CT;66%的人要求进行SIBO呼吸测试;96%有排便障碍症状的IBS-C患者需要肛肠测压。治疗数据:抗痉挛药物是最广泛使用的处方药,根据IBS亚型和当地可获得性而有所不同;83%建议低FODMAP饮食;对于IBS-D和腹胀,超过90%的患者开利福昔明和/或益生菌,81%的患者开降胆固醇胺;在IBS-C中,最常用的治疗方法是聚乙二醇、车前草、普鲁卡必利和利那氯肽;高达94%的患者将神经调节剂作为二线治疗;99%的人认为抑郁症患者需要心理治疗。结论虽然大多数专家根据指南诊断和治疗IBS,但在当地可获得性方面存在差异,并且腹部骨盆CT似乎被过度使用。了解全科医生和内科医生如何管理这一实体,将有助于建立根据国家调整的IBS诊断和治疗的实用指南。
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引用次数: 0
Hallazgo inusual durante una colonoscopia: ¡una cucaracha! 结肠镜检查中不寻常的发现:一只蟑螂!
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.05.009
J. Rodríguez-Castellot, P. Alonso-Castellano
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引用次数: 0
Intususcepción intestinal como manifestación clínica de adenocarcinoma primario de íleon terminal 肠直觉作为原发性终丝腺癌的临床表现
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.04.011
F.J. Valentin , C.S. Silva , A. Alfaro , L.E. Zamora-Nava , C. Ortiz
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引用次数: 0
Obstrucción biliar luego de migración de coils colocados para el manejo de pseudoaneurisma de la arteria hepática posterior a la colocación de prótesis biliar 为治疗胆道假体植入后的肝动脉假动脉瘤而植入的线圈移位后胆道阻塞
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.07.005
R.A. Rincón-Sánchez
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引用次数: 0
Virus de Epstein-Barr como causa de úlceras rectales en paciente con inmunosupresión: reporte de caso 爱泼斯坦-巴尔病毒作为免疫抑制患者直肠溃疡的病因:病例报告
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.06.012
F.J. Valentín-Cortez , C.S. Silva-Ramos , C.F. Ortiz-Hidalgo , J. Lizardi-Montaño , J. Lizardi-Cervera
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引用次数: 0
Compromiso gastrointestinal alto secundario a plasmocitoma extramedular: presentación inusual en un paciente inmunosuprimido 继发性高胃肠道对髓外浆细胞瘤的损害:在免疫抑制患者中不寻常的发生
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.04.006
S.A. Hernández, A. Chaar, F. Ávila, S. Sambracos
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引用次数: 0
Tumor neuroendocrino en el ciego; una causa inusual de diarrea crónica en un adulto joven 盲人神经内分泌肿瘤;年轻人慢性腹泻的不寻常原因
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.05.007
D.A. Calle-Rodas , M.A. Corral-Cazorla , P.D. Muñoz-Espinoza , C.A. Machuca-Carpio , J.D. Cordero-García
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引用次数: 0
Características clínicas y tratamiento de la esofagitis eosinofílica en población adulta en Colombia 哥伦比亚成人嗜酸性食管炎的临床特征和治疗
IF 1.7 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-10-01 DOI: 10.1016/j.rgmx.2025.04.004
F. Juliao-Baños , A. Lúquez-Mindiola , A. Gómez-Venegas , V. Parra-Izquierdo , H. Marulanda-Fernández , J. Carvajal-Gutiérrez , B. Arturo-Arias , P. Aponte-Ordoñez , V. Parra-Vargas , J. Toro-Calle , C. Rodríguez-Rubiano , R. Prieto-Ortiz , R. Carmona-Valle , A. Castro-Rodríguez , F. Gil-Parada , J. Castaño-Morales , J. Velásquez-Lopera , J. Donado-Gómez , W. Otero-Regino

Introduction and aim

There is an increase in the incidence and prevalence of eosinophilic esophagitis (EoE) worldwide and data in Latin America are scarce. The aim of our study was to describe the epidemiologic and clinical characteristics of EoE and its treatment, in adult patients in Colombia.

Patients and methods

A descriptive, cross-sectional study was conducted on patients with EoE, with the participation of 16 gastroenterologists from different Colombian cities. Demographic and clinical variables of the patients were evaluated, along with their treatment and complications. EoE severity was calculated utilizing the clinical severity index (CSI).

Results

The study included 152 patients with EoE seen within the time frame of November 2023 and July 2024. A total of 58.6% were men and the mean patient age at diagnosis was 43.3 years (range: 18-79). The time from symptom onset to diagnosis was 32.5 months (median), with an interquartile range (25-75%) of 11.0-79.8 months. A total of 134 (88.2%) patients received treatment with proton pump inhibitors (PPIs), 66 (43.4%) had dietary treatment, 42 (27.6%) received steroids, and 9 (5.9%) underwent endoscopic dilatation. A total of 57.2% of the patients received combination therapy. Histologic remission was achieved in 68.4% of the patients and dysphagia improved in 93.4% of the cases. In relation to the CSI, histologic remission was achieved in 75.6% of the patients with mild disease activity, in 63.9% with moderate activity, and in 50% with severe activity (P=.003).

Conclusions

Our results showed there is an important delay in the diagnosis of EoE in Colombia. The most widely used treatment was with PPIs, but more than half the patients had combination therapy. National management guidelines that consider local treatment availability need to be developed.
世界范围内嗜酸性粒细胞性食管炎(EoE)的发病率和流行率都在增加,而拉丁美洲的相关数据很少。本研究的目的是描述哥伦比亚成年患者EoE的流行病学和临床特征及其治疗方法。患者和方法对来自哥伦比亚不同城市的16名胃肠病学家参与的EoE患者进行了一项描述性横断面研究。评估患者的人口学和临床变量,以及他们的治疗和并发症。利用临床严重程度指数(CSI)计算EoE严重程度。结果该研究纳入了2023年11月至2024年7月期间就诊的152例EoE患者。58.6%为男性,诊断时平均年龄为43.3岁(范围:18-79岁)。从症状出现到诊断的时间为32.5个月(中位数),四分位数间距(25-75%)为11.0-79.8个月。共有134例(88.2%)患者接受质子泵抑制剂(PPIs)治疗,66例(43.4%)患者接受饮食治疗,42例(27.6%)患者接受类固醇治疗,9例(5.9%)患者接受内镜扩张治疗。共有57.2%的患者接受了联合治疗。68.4%的患者获得组织学缓解,93.4%的患者吞咽困难得到改善。与CSI相关,75.6%的轻度疾病活动期患者、63.9%的中度疾病活动期患者和50%的重度疾病活动期患者达到组织学缓解(P= 0.003)。结论研究结果显示,哥伦比亚的EoE诊断存在严重的延误。最广泛使用的治疗方法是PPIs,但超过一半的患者采用联合治疗。需要制定考虑到当地治疗可得性的国家管理指南。
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引用次数: 0
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Revista de Gastroenterologia de Mexico
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