Pub Date : 2024-07-01DOI: 10.1016/j.rgmx.2024.04.001
{"title":"Upadacitinib en una paciente con enfermedad de Crohn con pérdida de respuesta a ustekinumab: reporte de un caso","authors":"","doi":"10.1016/j.rgmx.2024.04.001","DOIUrl":"10.1016/j.rgmx.2024.04.001","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090624000375/pdfft?md5=4415c741158224d1451b5c95bcda15f0&pid=1-s2.0-S0375090624000375-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141954736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.rgmx.2023.01.001
D. Tueme-de la Peña , E.A. Salgado-Gamboa , J.I. Ortiz de Elguea-Lizárraga , M. Zambrano Lara , H.A. Rangel-Ríos , A.F. Chapa-Lobo , L.E. Salgado-Cruz
Introduction and aims
An anastomotic leak is one of the most dreaded complications in colorectal surgery because it increases postoperative morbidity and mortality. The aim of the present study was to identify whether indocyanine green fluorescence angiography (ICGFA) reduced the anastomotic dehiscence rate in colorectal surgery.
Material and methods
A retrospective study on patients that underwent colorectal surgery with colonic resection or low anterior resection and primary anastomosis, within the time frame of January 2019 and September 2021, was conducted. The patients were divided into the case group, in which ICGFA was performed for the intraoperative evaluation of blood perfusion at the anastomosis site, and the control group, in which ICGFA was not utilized.
Results
A total of 168 medical records were reviewed, resulting in 83 cases and 85 controls. Inadequate perfusion that required changing the surgical site of the anastomosis was identified in 4.8% of the case group (n = 4). A trend toward reducing the leak rate with ICGFA was identified (6% [n = 5] in the cases vs 7.1% in the controls [n = 6] [P = .999]). The patients that underwent anastomosis site change due to inadequate perfusion had a 0% leak rate.
Conclusions
ICGFA as a method to evaluate intraoperative blood perfusion showed a trend toward reducing the incidence of anastomotic leak in colorectal surgery.
{"title":"Angiografía por fluorescencia con verde de indocianina en cirugía colorrectal: análisis retrospectivo de casos y controles en México","authors":"D. Tueme-de la Peña , E.A. Salgado-Gamboa , J.I. Ortiz de Elguea-Lizárraga , M. Zambrano Lara , H.A. Rangel-Ríos , A.F. Chapa-Lobo , L.E. Salgado-Cruz","doi":"10.1016/j.rgmx.2023.01.001","DOIUrl":"10.1016/j.rgmx.2023.01.001","url":null,"abstract":"<div><h3>Introduction and aims</h3><p>An anastomotic leak is one of the most dreaded complications in colorectal surgery because it increases postoperative morbidity and mortality. The aim of the present study was to identify whether indocyanine green fluorescence angiography (ICGFA) reduced the anastomotic dehiscence rate in colorectal surgery.</p></div><div><h3>Material and methods</h3><p>A retrospective study on patients that underwent colorectal surgery with colonic resection or low anterior resection and primary anastomosis, within the time frame of January 2019 and September 2021, was conducted. The patients were divided into the case group, in which ICGFA was performed for the intraoperative evaluation of blood perfusion at the anastomosis site, and the control group, in which ICGFA was not utilized.</p></div><div><h3>Results</h3><p>A total of 168 medical records were reviewed, resulting in 83 cases and 85 controls. Inadequate perfusion that required changing the surgical site of the anastomosis was identified in 4.8% of the case group (n<!--> <!-->=<!--> <!-->4). A trend toward reducing the leak rate with ICGFA was identified (6% [n<!--> <!-->=<!--> <!-->5] in the cases vs 7.1% in the controls [n<!--> <!-->=<!--> <!-->6] [<em>P</em> <!-->=<!--> <!-->.999]). The patients that underwent anastomosis site change due to inadequate perfusion had a 0% leak rate.</p></div><div><h3>Conclusions</h3><p>ICGFA as a method to evaluate intraoperative blood perfusion showed a trend toward reducing the incidence of anastomotic leak in colorectal surgery.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090623000083/pdfft?md5=e9dbf9b9215851f3856a4173b77b9b3d&pid=1-s2.0-S0375090623000083-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45151650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Capsule endoscopy is part of the diagnostic approach to patients with suspected small bowel bleeding and data on its clinical impact are still limited in developing countries. The primary aim of the present study was to determine its impact on subsequent diagnostic and therapeutic decisions.
Material and methods
A retrospective study was conducted that included all the patients that underwent capsule endoscopy with the PillCam™ SB 3 Capsule system due to suspected small bowel bleeding treated at the Hospital Universitario Fundación Valle del Lili between January 2011 and December 2020.
Results
A total of 158 patients met the inclusion criteria. Mean patient age was 63 years (interquartile range [IQR], 52-74), 53.6% of the patients were women, and high blood pressure was the most frequent comorbidity (43.7%). The main indication was overt bleeding (58.2%). Of all the capsule endoscopies carried out, 63.9% showed lesions that were potentially responsible for bleeding. Medical or surgical treatment was indicated in 63.3% of the case total. Rebleeding at 6 months occurred in 15 patients and there were 2 deaths due to gastrointestinal bleeding at 6 months.
Conclusions
Capsule endoscopy has a high impact on patients with suspected small bowel bleeding, with respect to clinical decision-making, as well as rebleeding, hospitalization, and mortality outcomes. The positivity rate of lesions potentially responsible for bleeding was similar to that reported in developed countries.
{"title":"Impacto clínico de la videocápsula endoscópica en pacientes con sospecha de hemorragia de intestino delgado: experiencia en un hospital de alta complejidad de Colombia","authors":"C.J. Vargas-Potes , I.L. Zapata-Vásquez , N.E. Rojas-Rojas , C.A. Rojas-Rodríguez","doi":"10.1016/j.rgmx.2023.04.006","DOIUrl":"10.1016/j.rgmx.2023.04.006","url":null,"abstract":"<div><h3>Introduction and aims</h3><p>Capsule endoscopy is part of the diagnostic approach to patients with suspected small bowel bleeding and data on its clinical impact are still limited in developing countries. The primary aim of the present study was to determine its impact on subsequent diagnostic and therapeutic decisions.</p></div><div><h3>Material and methods</h3><p>A retrospective study was conducted that included all the patients that underwent capsule endoscopy with the PillCam™ SB 3 Capsule system due to suspected small bowel bleeding treated at the Hospital Universitario Fundación Valle del Lili between January 2011 and December 2020.</p></div><div><h3>Results</h3><p>A total of 158 patients met the inclusion criteria. Mean patient age was 63<!--> <!-->years (interquartile range [IQR], 52-74), 53.6% of the patients were women, and high blood pressure was the most frequent comorbidity (43.7%). The main indication was overt bleeding (58.2%). Of all the capsule endoscopies carried out, 63.9% showed lesions that were potentially responsible for bleeding. Medical or surgical treatment was indicated in 63.3% of the case total. Rebleeding at 6<!--> <!-->months occurred in 15 patients and there were 2<!--> <!-->deaths due to gastrointestinal bleeding at 6<!--> <!-->months.</p></div><div><h3>Conclusions</h3><p>Capsule endoscopy has a high impact on patients with suspected small bowel bleeding, with respect to clinical decision-making, as well as rebleeding, hospitalization, and mortality outcomes. The positivity rate of lesions potentially responsible for bleeding was similar to that reported in developed countries.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090623000551/pdfft?md5=e8afb13bd09e42b415d4935b4c74e46a&pid=1-s2.0-S0375090623000551-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46688317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.rgmx.2024.01.003
Z. Berger, F. Orellana, F. Torres, D. Simian, G. Araneda, P. Toledo
{"title":"Respuesta a Saavedra y Seguil sobre: ¿Es la esteatosis pancreática un hallazgo frecuente en la población chilena?","authors":"Z. Berger, F. Orellana, F. Torres, D. Simian, G. Araneda, P. Toledo","doi":"10.1016/j.rgmx.2024.01.003","DOIUrl":"10.1016/j.rgmx.2024.01.003","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090624000107/pdfft?md5=b9e058bf1b0c9171207958d17ee664e3&pid=1-s2.0-S0375090624000107-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140406973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.rgmx.2023.06.004
A. Fernández-Ramírez , A. Olivas-Martinez , J. Ruiz-Manriquez , E. Kauffman-Ortega , C. Moctezuma-Velázquez , E. Marquez-Guillen , A.G. Contreras , M. Vilatobá , E. González-Flores , R. Cruz-Martínez , N.C. Flores-García , I. García-Juárez
Introduction and aims
Posttransplantation diabetes mellitus (PTDM) is a serious long-term complication that has a negative impact on graft and patient survival. The purpose of the present study was to describe the incidence of PTDM in a Mexican cohort and evaluate its association with a previous family history of diabetes (FHD).
Methods
A retrospective single-center cohort study was conducted on patients undergoing liver transplantation. The primary outcome was time from liver transplantation to PTDM. The diagnosis of PTDM was established using the ADA criteria. A mediation analysis that used adjusted Cox regression models and considered pretransplant prediabetes a mediator was performed, to determine the total effect and direct effect of FHD on PTDM.
Results
A total of 152 patients were included, with a median follow-up time of 41 months; 19.2% (n = 29) had pretransplant diabetes. During the follow-up time, 15% of patients developed PTDM (n = 23), with an incidence rate of 4.71 cases/100 person-years. PTDM was significantly higher in patients with FHD, compared with those with no FHD (8.72 cases/100 person-years vs 2.04 cases/100 person-years, respectively; P = .001). The adjusted hazard ratio of PTDM for FHD was 4.14 (95% CI 1.60-10.7), P = .005) and 3.48 (95% CI 1.35-9.01, P = .010), when further controlled for pretransplant prediabetes.
Conclusion
The occurrence of PTDM was similar to that reported in most international studies. As with type 2 diabetes, family history plays an important role in the development of PTDM, even after accounting for pretransplant prediabetes. Patients with FHD should undergo a stricter metabolic program.
{"title":"Diabetes mellitus posterior a trasplante hepático y el impacto del antecedente familiar de diabetes en una cohorte mexicana","authors":"A. Fernández-Ramírez , A. Olivas-Martinez , J. Ruiz-Manriquez , E. Kauffman-Ortega , C. Moctezuma-Velázquez , E. Marquez-Guillen , A.G. Contreras , M. Vilatobá , E. González-Flores , R. Cruz-Martínez , N.C. Flores-García , I. García-Juárez","doi":"10.1016/j.rgmx.2023.06.004","DOIUrl":"10.1016/j.rgmx.2023.06.004","url":null,"abstract":"<div><h3>Introduction and aims</h3><p>Posttransplantation diabetes mellitus (PTDM) is a serious long-term complication that has a negative impact on graft and patient survival. The purpose of the present study was to describe the incidence of PTDM in a Mexican cohort and evaluate its association with a previous family history of diabetes (FHD).</p></div><div><h3>Methods</h3><p>A retrospective single-center cohort study was conducted on patients undergoing liver transplantation. The primary outcome was time from liver transplantation to PTDM. The diagnosis of PTDM was established using the ADA criteria. A mediation analysis that used adjusted Cox regression models and considered pretransplant prediabetes a mediator was performed, to determine the total effect and direct effect of FHD on PTDM.</p></div><div><h3>Results</h3><p>A total of 152 patients were included, with a median follow-up time of 41 months; 19.2% (n<!--> <!-->=<!--> <!-->29) had pretransplant diabetes. During the follow-up time, 15% of patients developed PTDM (n<!--> <!-->=<!--> <!-->23), with an incidence rate of 4.71 cases/100 person-years. PTDM was significantly higher in patients with FHD, compared with those with no FHD (8.72 cases/100 person-years <em>vs</em> 2.04 cases/100 person-years, respectively; <em>P</em> <!-->=<!--> <!-->.001). The adjusted hazard ratio of PTDM for FHD was 4.14 (95% CI 1.60-10.7), <em>P</em> <!-->=<!--> <!-->.005) and 3.48 (95% CI 1.35-9.01, <em>P</em> <!-->=<!--> <!-->.010), when further controlled for pretransplant prediabetes.</p></div><div><h3>Conclusion</h3><p>The occurrence of PTDM was similar to that reported in most international studies. As with type 2 diabetes, family history plays an important role in the development of PTDM, even after accounting for pretransplant prediabetes. Patients with FHD should undergo a stricter metabolic program.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090623000800/pdfft?md5=6347b9bf36aa398e0c2026a20b58d60f&pid=1-s2.0-S0375090623000800-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135605800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.rgmx.2023.03.007
D.G. Fernández-Ávila , V. Dávila-Ruales
Introduction and aims
Inflammatory bowel disease (IBD) has a high economic burden due to its chronicity. Treatment has evolved, thanks to the understanding of IBD pathogenesis and the advent of biologic therapy, albeit the latter increases direct costs. The aim of the present study was to calculate the total cost and cost per patient/year of biologic therapy for IBD and IBD-associated arthropathy in Colombia.
Methods
A descriptive study was conducted. The data were obtained from the Comprehensive Social Protection Information System of the Department of Health for the year 2019, utilizing the medical diagnosis codes of the International Classification of Diseases related to IBD and IBD-associated arthropathy as keywords.
Results
The prevalence of IBD and IBD-associated arthropathy was 61 cases per 100,000 inhabitants, with a female-to-male ratio of 1.5:1. Joint involvement was 3%, and 6.3% of the persons with IBD and IBD-associated arthropathy received biologic therapy. Adalimumab was the most widely prescribed biologic drug (49.2%). Biologic therapy had a cost of $15,926,302 USD and the mean cost per patient/year was $18,428 USD. Adalimumab had the highest impact on healthcare resource utilization, with a total cost of $7,672,320 USD. According to subtype, ulcerative colitis had the highest cost ($10,932,489 USD).
Conclusion
Biologic therapy is expensive, but its annual cost in Colombia is lower than that of other countries due to the government's regulation of high-cost medications.
{"title":"Frecuencia de uso y costo del tratamiento biológico para enfermedad inflamatoria intestinal y artropatía asociada a enfermedad inflamatoria intestinal en Colombia durante el año 2019","authors":"D.G. Fernández-Ávila , V. Dávila-Ruales","doi":"10.1016/j.rgmx.2023.03.007","DOIUrl":"10.1016/j.rgmx.2023.03.007","url":null,"abstract":"<div><h3>Introduction and aims</h3><p>Inflammatory bowel disease (IBD) has a high economic burden due to its chronicity. Treatment has evolved, thanks to the understanding of IBD pathogenesis and the advent of biologic therapy, albeit the latter increases direct costs. The aim of the present study was to calculate the total cost and cost per patient/year of biologic therapy for IBD and IBD-associated arthropathy in Colombia.</p></div><div><h3>Methods</h3><p>A descriptive study was conducted. The data were obtained from the Comprehensive Social Protection Information System of the Department of Health for the year 2019, utilizing the medical diagnosis codes of the International Classification of Diseases related to IBD and IBD-associated arthropathy as keywords.</p></div><div><h3>Results</h3><p>The prevalence of IBD and IBD-associated arthropathy was 61 cases per 100,000 inhabitants, with a female-to-male ratio of 1.5:1. Joint involvement was 3%, and 6.3% of the persons with IBD and IBD-associated arthropathy received biologic therapy. Adalimumab was the most widely prescribed biologic drug (49.2%). Biologic therapy had a cost of $15,926,302 USD and the mean cost per patient/year was $18,428 USD. Adalimumab had the highest impact on healthcare resource utilization, with a total cost of $7,672,320 USD. According to subtype, ulcerative colitis had the highest cost ($10,932,489 USD).</p></div><div><h3>Conclusion</h3><p>Biologic therapy is expensive, but its annual cost in Colombia is lower than that of other countries due to the government's regulation of high-cost medications.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090623000381/pdfft?md5=887755f7e69e7192a02d6f9467fca972&pid=1-s2.0-S0375090623000381-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44143824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.rgmx.2023.01.003
J. Contreras-Mancilla , J.P. Cerapio , E. Ruiz , R. Fernández , S. Casavilca-Zambrano , C. Machicado , J.J. Fournié , P. Pineau , S. Bertani
Introduction
Hepatocellular carcinoma (HCC) is the third most frequent cancer of digestive tract tumors in Peru, with a high mortality rate of 17.7 per 100,000 inhabitants. A significant number of HCC cases in Peru do not follow the classic clinical epidemiology of the disease described in other parts of the world. Those patients present with a distinct transcriptome profile and a singular tumor process, suggesting a particular type of hepatocarcinogenesis in a portion of the Peruvian population.
Aim
Our aim was to understand the clinical and biologic involvement of the epigenetic profile (methylation) and gene expression (transcriptome) of HCC in Peruvian patients.
Methods
HCC and liver transcriptome and DNA methylation profiles were evaluated in 74 Peruvian patients.
Results
When grouped by age, there was greater DNA methylation in younger patients with HCC but no differences with respect to the transcriptomic profile. A high prevalence of the hepatitis B virus (HBV) (> 90%) was also observed in the younger patients with HCC. Enrichment analyses in both molecular profiles pinpointed PRC2 as an important molecular effector of that liver tumor process in Peruvian patients.
Conclusion
HCC in Peruvian patients has a unique molecular profile, associated with the presence of HBV, as well as overall DNA hypermethylation related to undifferentiated liver cells or cellular reprogramming.
{"title":"Carcinoma hepatocelular en Perú: una descripción molecular de un cuadro clínico atípico","authors":"J. Contreras-Mancilla , J.P. Cerapio , E. Ruiz , R. Fernández , S. Casavilca-Zambrano , C. Machicado , J.J. Fournié , P. Pineau , S. Bertani","doi":"10.1016/j.rgmx.2023.01.003","DOIUrl":"10.1016/j.rgmx.2023.01.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Hepatocellular carcinoma (HCC) is the third most frequent cancer of digestive tract tumors in Peru, with a high mortality rate of 17.7 per 100,000 inhabitants. A significant number of HCC cases in Peru do not follow the classic clinical epidemiology of the disease described in other parts of the world. Those patients present with a distinct transcriptome profile and a singular tumor process, suggesting a particular type of hepatocarcinogenesis in a portion of the Peruvian population.</p></div><div><h3>Aim</h3><p>Our aim was to understand the clinical and biologic involvement of the epigenetic profile (methylation) and gene expression (transcriptome) of HCC in Peruvian patients.</p></div><div><h3>Methods</h3><p>HCC and liver transcriptome and DNA methylation profiles were evaluated in 74 Peruvian patients.</p></div><div><h3>Results</h3><p>When grouped by age, there was greater DNA methylation in younger patients with HCC but no differences with respect to the transcriptomic profile. A high prevalence of the hepatitis B virus (HBV) (> 90%) was also observed in the younger patients with HCC. Enrichment analyses in both molecular profiles pinpointed PRC2 as an important molecular effector of that liver tumor process in Peruvian patients.</p></div><div><h3>Conclusion</h3><p>HCC in Peruvian patients has a unique molecular profile, associated with the presence of HBV, as well as overall DNA hypermethylation related to undifferentiated liver cells or cellular reprogramming.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090623000137/pdfft?md5=50cdca3ea970a3bddf39b3908fdbe6f6&pid=1-s2.0-S0375090623000137-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48665813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A large number of patients with autoimmune hepatitis (AH) seek information about their disease on the internet. The reliability, comprehensiveness, and quality of said information in Spanish has not been studied.
Aim
Our aim was to describe the characteristics of the information about AH on YouTube®.
Methods
An analytic observational study evaluated videos in Spanish about AH available on YouTube®, describing their general characteristics, viewer engagement, and information sources. Standardized tools were utilized to analyze reliability (DISCERN), comprehensiveness, and overall quality (Global Quality Score [GQS]).
Results
One hundred videos were included, 93% of which provided information from healthcare professionals (group 1), and 7% of which reflected patient opinions (group 2). There were differences in the median reliability (DISCERN: 4 vs 2, P ≤ .05) and comprehensiveness (4 vs 2, P ≤ .05) scores between groups, but equal overall quality (GQS 3 vs 2, P = .2). Reliability (DISCERN: 4; IQR: 3-4) and comprehensiveness (4.5; IQR: 3-5) were higher in videos by professional organizations, compared with those by independent users, healthcare information websites, and for-profit organizations (DISCERN: 3; IQR: 2.5-3.5; P < .001). Reliability (DISCERN: 2; IQR: 1.5-3), comprehensiveness (2; IQR; 1.5-2.5), and quality (GQS: 2.5; IQR: 1.5-3.5) were lower for videos made by for-profit organizations.
Conclusion
The majority of videos about AH in Spanish on YouTube® have good reliability, comprehensiveness, and quality. Videos created by academic organizations had higher scores, thus their collaboration, with respect to patient opinion videos, is suggested.
{"title":"YouTube® en español como fuente de información para pacientes con hepatitis autoinmune","authors":"C.E. Lombo-Moreno , O.M. Muñoz-Velandia , D.G. Fernández-Ávila , J.E. Barahona-Correa , H.C. Aranguren , F.A. Avila","doi":"10.1016/j.rgmx.2023.03.006","DOIUrl":"10.1016/j.rgmx.2023.03.006","url":null,"abstract":"<div><h3>Introduction</h3><p>A large number of patients with autoimmune hepatitis (AH) seek information about their disease on the internet. The reliability, comprehensiveness, and quality of said information in Spanish has not been studied.</p></div><div><h3>Aim</h3><p>Our aim was to describe the characteristics of the information about AH on YouTube®.</p></div><div><h3>Methods</h3><p>An analytic observational study evaluated videos in Spanish about AH available on YouTube®, describing their general characteristics, viewer engagement, and information sources. Standardized tools were utilized to analyze reliability (DISCERN), comprehensiveness, and overall quality (Global Quality Score [GQS]).</p></div><div><h3>Results</h3><p>One hundred videos were included, 93% of which provided information from healthcare professionals (group<!--> <!-->1), and 7% of which reflected patient opinions (group<!--> <!-->2). There were differences in the median reliability (DISCERN: 4 vs 2, <em>P</em> <!-->≤<!--> <!-->.05) and comprehensiveness (4 vs 2, <em>P</em> <!-->≤<!--> <!-->.05) scores between groups, but equal overall quality (GQS 3 vs 2, <em>P</em> <!-->=<!--> <!-->.2). Reliability (DISCERN: 4; IQR: 3-4) and comprehensiveness (4.5; IQR: 3-5) were higher in videos by professional organizations, compared with those by independent users, healthcare information websites, and for-profit organizations (DISCERN: 3; IQR: 2.5-3.5; <em>P</em> <!--><<!--> <!-->.001). Reliability (DISCERN: 2; IQR: 1.5-3), comprehensiveness (2; IQR; 1.5-2.5), and quality (GQS: 2.5; IQR: 1.5-3.5) were lower for videos made by for-profit organizations.</p></div><div><h3>Conclusion</h3><p>The majority of videos about AH in Spanish on YouTube® have good reliability, comprehensiveness, and quality. Videos created by academic organizations had higher scores, thus their collaboration, with respect to patient opinion videos, is suggested.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090623000241/pdfft?md5=54f68ce5822462e7cbc3b797b89450ec&pid=1-s2.0-S0375090623000241-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44990678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.rgmx.2023.04.004
S. Özdemir , İ. Altunok , A. Özkan , M.M. İslam , A. Algın , S.E. Eroğlu , G. Aksel
Introduction and aims
We aimed to investigate changes in initial platelet indices in patients arriving at the emergency department with acute cholecystitis.
Material and methods
A retrospective case-control study was conducted at a tertiary care teaching hospital. Demographics, comorbidities, laboratory data, length of hospital stay, and mortality data for the acute cholecystitis group were retrospectively obtained from the hospital digital database. Platelet count, mean platelet volume, plateletcrit, platelet distribution width, and platelet mass index were collected.
Results
A total of 553 patients with acute cholecystitis were the study cases, and 541 hospital employees were the study controls. According to the results of the multivariate analysis of the platelet indices studied, only mean platelet volume and platelet distribution width showed significant differences between the two groups (adjusted odds ratio: 2; 95% confidence interval: 1.4-2.7; P < .001 and adjusted odds ratio: 5.88; 95% confidence interval: 2.44-14.4; P < .001, respectively). The multivariate regression model created had an area under the curve of 0.969 in the prediction of acute cholecystitis (accuracy: 0.917; sensitivity: 89%; specificity: 94.5%).
Conclusion
The study results indicate that the initial mean platelet volume and platelet distribution width were independent predictors of acute cholecystitis.
{"title":"Relación entre los índices plaquetarios en colecistitis aguda: un estudio de casos y controles","authors":"S. Özdemir , İ. Altunok , A. Özkan , M.M. İslam , A. Algın , S.E. Eroğlu , G. Aksel","doi":"10.1016/j.rgmx.2023.04.004","DOIUrl":"10.1016/j.rgmx.2023.04.004","url":null,"abstract":"<div><h3>Introduction and aims</h3><p>We aimed to investigate changes in initial platelet indices in patients arriving at the emergency department with acute cholecystitis.</p></div><div><h3>Material and methods</h3><p>A retrospective case-control study was conducted at a tertiary care teaching hospital. Demographics, comorbidities, laboratory data, length of hospital stay, and mortality data for the acute cholecystitis group were retrospectively obtained from the hospital digital database. Platelet count, mean platelet volume, plateletcrit, platelet distribution width, and platelet mass index were collected.</p></div><div><h3>Results</h3><p>A total of 553 patients with acute cholecystitis were the study cases, and 541 hospital employees were the study controls. According to the results of the multivariate analysis of the platelet indices studied, only mean platelet volume and platelet distribution width showed significant differences between the two groups (adjusted odds ratio: 2; 95% confidence interval: 1.4-2.7; <em>P</em> <!--><<!--> <!-->.001 and adjusted odds ratio: 5.88; 95% confidence interval: 2.44-14.4; <em>P</em> <!--><<!--> <!-->.001, respectively). The multivariate regression model created had an area under the curve of 0.969 in the prediction of acute cholecystitis (accuracy: 0.917; sensitivity: 89%; specificity: 94.5%).</p></div><div><h3>Conclusion</h3><p>The study results indicate that the initial mean platelet volume and platelet distribution width were independent predictors of acute cholecystitis.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090623000538/pdfft?md5=348c205b52c43aab1f81c0fba012d717&pid=1-s2.0-S0375090623000538-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43527063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.rgmx.2022.09.004
C.E. Lombo-Moreno , O.M. Muñoz-Velandia , D.G. Fernández-Ávila , J.E. Barahona-Correa , V. López-Ramírez , A. Rodriguez-Varon
Introduction and aim
The majority of patients with inflammatory bowel disease (IBD) seek information about their disease on the internet. The reliability, comprehensiveness, and quality of said information in Spanish has not previously been studied.
Materials and methods
An analytic observational study was conducted that included YouTube® videos on IBD available in Spanish, describing general characteristics, engagement, and sources. Standard tools for evaluating reliability (DISCERN), comprehensiveness, and overall quality (Global Quality Score [GQS]) were employed.
Results
One hundred videos were included. Eighty-eight videos consisted of information produced by healthcare professionals (group 1) and 12 included patient opinions (group 2). There were no differences in the median scores for reliability (DISCERN: 3 vs 3, P = .554) or comprehensiveness (3 vs 2.5, P = .768) between the two groups, but there was greater overall quality in the group 2 videos (GQS 3 vs 4, P = .007). Reliability was higher for the videos produced by professional organizations (DISCERN: 4; IQR: 3-4), when compared with healthcare information websites and for-profit agencies (DISCERN: 3; IQR: 2.5-3.5) (P < .001), but the videos with healthcare information website and for-profit sources had a higher quality score (GQS: 3 vs 4, P < .001). Comprehensiveness scores were similar.
Conclusion
The majority of YouTube® videos in Spanish on IBD have good reliability, comprehensiveness, and quality. Reliability was greater for the videos produced by professional organizations, whereas quality was higher for those created from healthcare information websites and for-profit agencies.
引言和目的大多数炎症性肠病（IBD）患者都在互联网上寻求有关其疾病的信息。材料与方法我们开展了一项分析性观察研究，其中包括 YouTube® 上有关 IBD 的西班牙语视频，并对其一般特征、参与度和来源进行了描述。研究采用了评估可靠性（DISCERN）、全面性和总体质量（全球质量评分 [GQS]）的标准工具。其中 88 个视频由医护人员制作（第 1 组），12 个视频包含患者意见（第 2 组）。两组视频在可靠性（DISCERN：3 vs 3，P = .554）和全面性（3 vs 2.5，P = .768）的中位数得分上没有差异，但第二组视频的整体质量更高（GQS 3 vs 4，P = .007）。与医疗保健信息网站和营利机构（DISCERN：3；IQR：2.5-3.5）相比，专业组织制作的视频（DISCERN：4；IQR：3-4）可靠性更高（P < .001），但医疗保健信息网站和营利机构制作的视频质量得分更高（GQS：3 vs 4，P < .001）。结论大多数 YouTube® 西班牙语 IBD 视频具有良好的可靠性、全面性和质量。专业组织制作的视频可靠性更高，而医疗保健信息网站和营利机构制作的视频质量更高。
{"title":"YouTube® en español como fuente de información para pacientes con enfermedad inflamatoria intestinal","authors":"C.E. Lombo-Moreno , O.M. Muñoz-Velandia , D.G. Fernández-Ávila , J.E. Barahona-Correa , V. López-Ramírez , A. Rodriguez-Varon","doi":"10.1016/j.rgmx.2022.09.004","DOIUrl":"10.1016/j.rgmx.2022.09.004","url":null,"abstract":"<div><h3>Introduction and aim</h3><p>The majority of patients with inflammatory bowel disease (IBD) seek information about their disease on the internet. The reliability, comprehensiveness, and quality of said information in Spanish has not previously been studied.</p></div><div><h3>Materials and methods</h3><p>An analytic observational study was conducted that included YouTube® videos on IBD available in Spanish, describing general characteristics, engagement, and sources. Standard tools for evaluating reliability (DISCERN), comprehensiveness, and overall quality (Global Quality Score [GQS]) were employed.</p></div><div><h3>Results</h3><p>One hundred videos were included. Eighty-eight videos consisted of information produced by healthcare professionals (group<!--> <!-->1) and 12 included patient opinions (group<!--> <!-->2). There were no differences in the median scores for reliability (DISCERN: 3 vs 3, <em>P</em> <!-->=<!--> <!-->.554) or comprehensiveness (3 vs 2.5, <em>P</em> <!-->=<!--> <!-->.768) between the two groups, but there was greater overall quality in the group<!--> <!-->2 videos (GQS 3 vs 4, <em>P</em> <!-->=<!--> <!-->.007). Reliability was higher for the videos produced by professional organizations (DISCERN: 4; IQR: 3-4), when compared with healthcare information websites and for-profit agencies (DISCERN: 3; IQR: 2.5-3.5) (<em>P</em> <!--><<!--> <!-->.001), but the videos with healthcare information website and for-profit sources had a higher quality score (GQS: 3 vs 4, <em>P</em> <!--><<!--> <!-->.001). Comprehensiveness scores were similar.</p></div><div><h3>Conclusion</h3><p>The majority of YouTube® videos in Spanish on IBD have good reliability, comprehensiveness, and quality. Reliability was greater for the videos produced by professional organizations, whereas quality was higher for those created from healthcare information websites and for-profit agencies.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090623000368/pdfft?md5=93e7eb02609742d737960fa83c254cef&pid=1-s2.0-S0375090623000368-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44151897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号