Pub Date : 2023-10-25DOI: 10.1007/s12410-023-09586-0
Joanne S. Sutter, W. Patricia Bandettini, Kalindi Parikh, Jeannie H. Yu, Eileen Gajo, Clifford J. Kavinsky, Annabelle Santos Volgman, Anupama K. Rao
{"title":"A Brief Overview of Sex Differences in Transcatheter Therapeutics in Valvular Heart Disease","authors":"Joanne S. Sutter, W. Patricia Bandettini, Kalindi Parikh, Jeannie H. Yu, Eileen Gajo, Clifford J. Kavinsky, Annabelle Santos Volgman, Anupama K. Rao","doi":"10.1007/s12410-023-09586-0","DOIUrl":"https://doi.org/10.1007/s12410-023-09586-0","url":null,"abstract":"","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135112879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-03DOI: 10.1007/s12410-023-09584-2
Marilia B. Voigt, Dmitrij Kravchenko, Alexander Isaak, Annkristin Heine, Tobias A. W. Holderried, Julian A. Luetkens
Abstract Purpose of Review To review the current and future role of cardiovascular magnetic resonance (CMR) assessment of immunotherapy cardiotoxicity. Recent Findings In patients who suffer from immune checkpoint inhibitor (ICI) myocarditis, pathologic CMR findings, including myocardial edema, reduced left ventricular ejection fraction (LVEF), late gadolinium enhancement (i.e., fibrosis and/or necrosis), and myocardial strain, are mostly subtle, but fulminant courses have been described. Individual cases of cardiotoxicity in chimeric antigen receptor (CAR) T cell therapy have also already been documented, but there are currently no studies addressing the role of CMR in CAR T cell therapy. There are also classes of immunotherapies for which no cases of cardiotoxicity are known yet, such as cytokines or adjuvants. Summary Together with patient symptoms, laboratory markers, electrocardiogram, and echocardiography, CMR is of high value in the diagnostic workup of immunotherapy-associated myocarditis in hemodynamically stable patients, according to recent guidelines. Additionally, quantitative strain analysis and T1 relaxation times with CMR can aid in assessing disease severity, prognosis, and patient outcomes with ICI-associated myocarditis. Future CMR studies on cardiotoxicity in CAR T cell therapy are needed.
{"title":"Cardiovascular Magnetic Resonance Assessment of Immunotherapy Cardiotoxicity","authors":"Marilia B. Voigt, Dmitrij Kravchenko, Alexander Isaak, Annkristin Heine, Tobias A. W. Holderried, Julian A. Luetkens","doi":"10.1007/s12410-023-09584-2","DOIUrl":"https://doi.org/10.1007/s12410-023-09584-2","url":null,"abstract":"Abstract Purpose of Review To review the current and future role of cardiovascular magnetic resonance (CMR) assessment of immunotherapy cardiotoxicity. Recent Findings In patients who suffer from immune checkpoint inhibitor (ICI) myocarditis, pathologic CMR findings, including myocardial edema, reduced left ventricular ejection fraction (LVEF), late gadolinium enhancement (i.e., fibrosis and/or necrosis), and myocardial strain, are mostly subtle, but fulminant courses have been described. Individual cases of cardiotoxicity in chimeric antigen receptor (CAR) T cell therapy have also already been documented, but there are currently no studies addressing the role of CMR in CAR T cell therapy. There are also classes of immunotherapies for which no cases of cardiotoxicity are known yet, such as cytokines or adjuvants. Summary Together with patient symptoms, laboratory markers, electrocardiogram, and echocardiography, CMR is of high value in the diagnostic workup of immunotherapy-associated myocarditis in hemodynamically stable patients, according to recent guidelines. Additionally, quantitative strain analysis and T1 relaxation times with CMR can aid in assessing disease severity, prognosis, and patient outcomes with ICI-associated myocarditis. Future CMR studies on cardiotoxicity in CAR T cell therapy are needed.","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135688973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-26DOI: 10.1007/s12410-023-09583-3
Cristina Elena Popescu, Paola Ferro, Irene Gotuzzo, Irene Burger, Axel Rominger, Federico Caobelli
Abstract Purpose of Review Myocardial fibrosis is a response to myocardial injury and plays a pivotal role in ventricular remodeling. Different patterns of fibrosis are associated with different disease states, but the presence and amount of fibrosis provide a different impact on prognosis. Recent Findings In the latest years, fibroblast activation protein inhibitor (FAPi) positron emission tomography (PET) gain interest for its potential in detecting myocardial fibrosis, in differentiating between active and chronic disease, and in the assessment of disease progression and response to treatment. Summary We aim to highlight the most relevant current applications of FAPi PET/CT in cardiovascular imaging, focusing on its applications, advantages, limitations, and to underline future clinical perspective.
{"title":"68Ga-FAPi: Pathways and Diagnosis in Cardiac Imaging","authors":"Cristina Elena Popescu, Paola Ferro, Irene Gotuzzo, Irene Burger, Axel Rominger, Federico Caobelli","doi":"10.1007/s12410-023-09583-3","DOIUrl":"https://doi.org/10.1007/s12410-023-09583-3","url":null,"abstract":"Abstract Purpose of Review Myocardial fibrosis is a response to myocardial injury and plays a pivotal role in ventricular remodeling. Different patterns of fibrosis are associated with different disease states, but the presence and amount of fibrosis provide a different impact on prognosis. Recent Findings In the latest years, fibroblast activation protein inhibitor (FAPi) positron emission tomography (PET) gain interest for its potential in detecting myocardial fibrosis, in differentiating between active and chronic disease, and in the assessment of disease progression and response to treatment. Summary We aim to highlight the most relevant current applications of FAPi PET/CT in cardiovascular imaging, focusing on its applications, advantages, limitations, and to underline future clinical perspective.","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134958280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-30DOI: 10.1007/s12410-023-09582-4
Mette Louise Gram Kjærulff, S. Madsen, T. V. Luong, K. Pryds, R. Nielsen, L. Gormsen
{"title":"Current Role of Myocardial Viability Imaging Using Positron Emission Tomography in Patients with Chronic Ischemic Heart Failure and Left Ventricular Dysfunction","authors":"Mette Louise Gram Kjærulff, S. Madsen, T. V. Luong, K. Pryds, R. Nielsen, L. Gormsen","doi":"10.1007/s12410-023-09582-4","DOIUrl":"https://doi.org/10.1007/s12410-023-09582-4","url":null,"abstract":"","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85998002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-18DOI: 10.1007/s12410-023-09580-6
R. Parikh, O. Khalique
{"title":"Selection of Ideal Candidates for Percutaneous Mitral Interventions","authors":"R. Parikh, O. Khalique","doi":"10.1007/s12410-023-09580-6","DOIUrl":"https://doi.org/10.1007/s12410-023-09580-6","url":null,"abstract":"","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72584279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-17DOI: 10.1007/s12410-023-09581-5
M. I. Planek, Shannon Li, Leyla Herbst, Joanne S Sutter, R. Sanghani, A. Volgman, Stuart H. Chen
{"title":"Cardiovascular Imaging During Pregnancy in Women with Congenital and Valvular Heart Disease","authors":"M. I. Planek, Shannon Li, Leyla Herbst, Joanne S Sutter, R. Sanghani, A. Volgman, Stuart H. Chen","doi":"10.1007/s12410-023-09581-5","DOIUrl":"https://doi.org/10.1007/s12410-023-09581-5","url":null,"abstract":"","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78431931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-23DOI: 10.1007/s12410-023-09578-0
Adriana D’Antonio, Maria Falzarano, Fabrizio Reina, R. Assante, E. Zampella, Francesca Maio, P. Buongiorno, M. Panico, C. Mainolfi, T. Mannarino, A. Cuocolo, W. Acampa
{"title":"Cardiac Perfusion and Innervation Assessment by CZT-SPECT: Have a Look to Simultaneous Dual-isotope Protocol","authors":"Adriana D’Antonio, Maria Falzarano, Fabrizio Reina, R. Assante, E. Zampella, Francesca Maio, P. Buongiorno, M. Panico, C. Mainolfi, T. Mannarino, A. Cuocolo, W. Acampa","doi":"10.1007/s12410-023-09578-0","DOIUrl":"https://doi.org/10.1007/s12410-023-09578-0","url":null,"abstract":"","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72390053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.1007/s12410-023-09576-2
D. Scharpf, M. Hennersdorf
{"title":"Echokardiography in ECLS","authors":"D. Scharpf, M. Hennersdorf","doi":"10.1007/s12410-023-09576-2","DOIUrl":"https://doi.org/10.1007/s12410-023-09576-2","url":null,"abstract":"","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75448227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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