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Impact of the organ-system integrated curriculum on the research productivity of a Philippine government medical school: An ARIMA-based bibliometric analysis 器官系统综合课程对菲律宾一所公立医学院研究成果的影响:基于 ARIMA 的文献计量分析
Pub Date : 2024-06-04 DOI: 10.54645/202417supifi-23
C. W. Turalde, Al Joseph Molina, Mario B. Prado, Erlyn Sana
The organ-system integrated (OSI) curriculum was pioneered in the country by the U.P. College of Medicine (UPCM) in 2004. Data on its impact on research productivity was lacking. This study aims to describe the trends in research productivity of UPCM in a time series and the impact of OSI implementation on publication trends. Relevant electronic databases (PubMed, Scopus, and WPRIM) were searched from the earliest indexed record until December 2023. The auto-regressive integrated moving average (ARIMA) time series analysis was used to compare the actual and predicted trends during the OSI implementation using the pre-OSI trend. A total of 2,705 articles were included. Acta Medica Philippina is the journal with the highest number of publications (n = 420, 20.24%). Although there is a considerable rise in the number of publications utilizing evidence synthesis and qualitative design, observational studies remain as the most common design (n = 293, 2021-2023 period). The leading clinical departments are Neurosciences and Medicine. The departments of Biochemistry and Clinical Epidemiology take the lead among basic sciences departments. Despite the glaring uptrend in publications concurrent with OSI implementation, the actual trend is not significantly different from the predicted trend (LR chi2(1) = 0.37; Prob > chi2 = 0.5432). The OSI curriculum did not significantly change the trend of productivity. Medical curriculum designers should revisit strategies dedicated for research competencies. It is imperative to include activities for qualitative and mixed-methods designs. Future studies should consider relevant critical events in the time series forecasting models and the scientific outputs in the grey literature.
器官系统整合(OSI)课程是由印度太平洋大学医学院(U.P. College of Medicine,UPCM)于 2004 年在该国首创的。但缺乏有关该课程对研究生产力影响的数据。本研究旨在描述UPCM研究生产率的时间序列趋势,以及OSI的实施对论文发表趋势的影响。研究人员在相关电子数据库(PubMed、Scopus 和 WPRIM)中搜索了从最早索引记录到 2023 年 12 月的数据。采用自动回归整合移动平均(ARIMA)时间序列分析法,利用实施开放社会倡议前的趋势,比较实施开放社会倡议期间的实际趋势和预测趋势。共纳入 2705 篇文章。Acta Medica Philippina 是发表文章数量最多的期刊(n = 420,20.24%)。尽管采用证据综合和定性设计的论文数量大幅增加,但观察性研究仍是最常见的设计(n = 293,2021-2023 年)。主要的临床科室是神经科学和医学。生物化学系和临床流行病学系在基础科学系中处于领先地位。尽管在实施开放社会科学倡议的同时,论文数量出现了明显的上升趋势,但实际趋势与预测趋势并无显著差异(LR chi2(1) = 0.37;概率 > chi2 = 0.5432)。OSI 课程并未明显改变生产率的趋势。医学课程设计者应重新审视专门培养研究能力的策略。必须纳入定性和混合方法设计活动。未来的研究应考虑时间序列预测模型中的相关关键事件和灰色文献中的科学成果。
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引用次数: 0
Intradialytic massage for leg cramps among hemodialysis patients: A single-center, randomized crossover trial 血液透析患者腿部抽筋的椎管内按摩:单中心随机交叉试验
Pub Date : 2024-04-24 DOI: 10.54645/202417supejr-14
Krizia Mari Anne Ramos-Daguman, Ed Jico Conde, Henry Angelo Go, Vince Bryan Viscayno, Monalisa Lim Dungca, Marissa Elizabeth Lim
Background: Leg cramps are commonly experienced by hemodialysis patients, and its persistence may lead to treatment noncompliance. Limited studies are available examining the efficacy of intradialytic massage on reducing leg cramps. Objectives: To determine the efficacy of intradialytic leg massage on reducing leg cramps among patients undergoing maintenance hemodialysis at the East Avenue Medical Center. Methodology: This is a single-center, randomized crossover trial. A total of 44 adult patients were randomized in a 1:1 ratio into two groups—Group A (intradialytic massage followed by control) and Group B (control followed by intradialytic massage). Each patient underwent the first assigned intervention for 2 weeks, followed by a washout period of 4 weeks, then the second intervention was performed for another 2 weeks. The primary outcomes were the change in frequency, duration, and intensity of cramps. The secondary outcome was patient quality of life. Results: A higher proportion of patients during the intervention period did not experience cramps post-intervention than during the control period; however, the results were not statistically significant (p=0.2059). The median change in frequency, duration, and intensity of leg cramps did not significantly differ between intervention and control (p>0.05). Moreover, quality of life measures were not significantly different between the two groups (p>0.05). Conclusion: Intradialytic massage alone is not efficacious in reducing leg cramp frequency, duration, and intensity. Moreover, intradialytic massage failed to improve the quality of life of patients undergoing hemodialysis treatment. Underlying factors that lead to leg cramps should be addressed through comprehensive and individualized interventions.
背景:腿部抽筋是血液透析患者的常见症状,其持续性可能导致患者不遵守治疗规定。有关血液透析内按摩对减轻腿部抽筋的疗效的研究十分有限。研究目的确定在东大街医疗中心接受维持性血液透析的患者中,椎管内腿部按摩对减轻腿部抽筋的效果。研究方法:这是一项单中心、随机交叉试验。共有 44 名成年患者按 1:1 的比例被随机分为两组--A 组(先进行椎管内按摩,再进行对照组治疗)和 B 组(先进行对照组治疗,再进行椎管内按摩)。每名患者先接受为期 2 周的第一种指定干预,然后是 4 周的冲洗期,接着再接受为期 2 周的第二种干预。主要结果是抽筋频率、持续时间和强度的变化。次要结果是患者的生活质量。结果:与对照组相比,干预期后未出现抽筋的患者比例更高,但结果无统计学意义(P=0.2059)。干预组和对照组在腿抽筋频率、持续时间和强度的中位数变化上没有显著差异(P>0.05)。此外,两组患者的生活质量也无明显差异(P>0.05)。结论单纯的椎管内按摩对减少腿部抽筋的频率、持续时间和强度没有效果。此外,椎管内按摩也无法改善血液透析患者的生活质量。应通过全面和个性化的干预措施来解决导致腿部抽筋的潜在因素。
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引用次数: 0
Diversity and novelty of venom peptides from Conus (Asprella) rolani revealed by analysis of its venom duct transcriptome 通过分析柯纳斯(Asprella)毒液导管转录组揭示其毒液肽的多样性和新颖性
Pub Date : 2024-04-22 DOI: 10.54645/202417supqch-42
Ryoichi Taguchi, Dan Jethro M Masacupan, Arturo Lluisma
Conus species in the sub-genus Asprella are poorly studied because they inhabit deep-water habitats. To date, only a few peptides have been characterized from this clade. In this study, the venom duct transcriptome of a member of this clade, Conus rolani, was mined for potential conopeptides. Using a high-throughput RNA sequencing platform (Illumina) and a multiple k-mer de novo assembly, we found 103 putative conopeptide precursor amino acid sequences, including the few peptides previously reported for this species. The sequences, predominantly novel based on amino acid sequence, were diverse, comprising 36 gene superfamilies (including the “unassigned” superfamilies). As observed in other Conus species, the O1 gene superfamily was the most diverse (12 distinct sequences) but interestingly none of the sequences were found to contain the conserved amino acids associated with certain bioactivities in peptides found in piscivorous Conus species. The O2 superfamily was also highly diverse but con-ikot-ikot and an unassigned superfamily (MMSRMG) were more diverse than the rest of the superfamilies. In terms of gene expression levels, the understudied MEFRR paralog of the ancestral divergent M---L-LTVA superfamily was found to be the most highly expressed in the transcriptome, suggesting a novel role. Additionally, a conopeptide with high sequence similarity to A2 secretory group XII phospholipases is the first reported member of this phospholipase group in Conus and potentially represents a novel superfamily, expanding the catalog of known phospholipases present in cone snail venoms. The discovery of these putative conopeptides provides the first but early glimpse of the diversity and novelty of the peptides in the Asprella group and sets the stage for their functional characterization.
由于 Asprella 亚属中的锥鱼类栖息于深水生境,因此对它们的研究很少。迄今为止,该支系只有少数肽段被鉴定。在本研究中,研究人员对该支系的一个成员 Conus rolani 的毒液导管转录组进行了挖掘,以发现潜在的锥肽。利用高通量 RNA 测序平台(Illumina)和多 k-mer 从头组装技术,我们发现了 103 个假定的锥肽前体氨基酸序列,包括之前报道过的该物种的少数几个肽。这些序列主要是基于氨基酸序列的新序列,具有多样性,包括 36 个基因超家族(包括 "未指定 "的超家族)。与在其他芋螺物种中观察到的情况一样,O1 基因超家族的多样性最高(12 个不同的序列),但有趣的是,这些序列中没有一个包含与食鱼芋螺(Conus)物种中发现的肽的某些生物活性相关的保守氨基酸。O2 超家族的多样性也很高,但 con-ikot-ikot 和一个未指定的超家族(MMSRMG)的多样性高于其他超家族。在基因表达水平方面,研究不足的祖先分化的M--L-LTVA超家族的MEFRR旁系亲属在转录组中的表达量最高,这表明其具有新的作用。此外,一种与 A2 分泌组 XII 磷脂酶序列高度相似的锥肽是第一个被报道的锥螺体内该磷脂酶组的成员,有可能代表一个新的超家族,从而扩展了锥螺毒液中已知磷脂酶的目录。这些假定的锥肽的发现为我们提供了对 Asprella 组肽的多样性和新颖性的初步了解,并为这些肽的功能表征奠定了基础。
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引用次数: 0
Predictors of interdependent happiness among health science students during the COVID-19 pandemic COVID-19 大流行期间健康科学专业学生相互依存幸福感的预测因素
Pub Date : 2024-04-19 DOI: 10.54645/202417supavr-28
Demuel Dee Berto, D. D. Dasig, Leticia Ibanez, Marlon L. Bayot
There are limited studies on the impact of the COVID-19 pandemic on the mental health of Filipino health science students, mainly those correlating a unique culturally related construct, such as interdependent happiness (IDH), to physiologic, health, and psychosocial factors. Cross-sectional data were collected to investigate the factors predicting the IDH of students at a private university during the COVID-19 pandemic. A seven-part online survey was completed by 180 respondents using convenience sampling. There was no evidence of multicollinearity issues in any of the independent variables. The findings revealed that 100% of respondents had poor sleep quality, a morning chronotype, and better eating habits. The majority (81%) had low levels of physical activity, low levels of social support (60%), and average levels of IDH (36.1%). Bivariate analyses revealed that sleep quality and chronotype were negatively associated with IDH. Dietary habits and social support were found to have a moderately positive relationship with IDH. Physical activity was not found to be significantly related to IDH. Regression analysis revealed three variables significantly associated with IDH: sleep quality, dietary habits, and social support. When age, gender, college, year level, family income, body mass index, and grade point average were all considered, there were no significant differences in the IDH of health science students. This study shows that sleep quality, dietary habits, and social support all predict IDH and should be considered when managing the psychological impact of COVID-19 or any future pandemics among students.
有关 COVID-19 大流行对菲律宾健康科学专业学生心理健康影响的研究非常有限,主要是那些将与文化相关的独特结构(如相互依存的幸福感(IDH))与生理、健康和社会心理因素相关联的研究。本研究收集了横断面数据,以调查在 COVID-19 大流行期间预测一所私立大学学生 IDH 的因素。通过便利抽样,180 名受访者完成了一项由七个部分组成的在线调查。没有证据表明任何自变量存在多重共线性问题。调查结果显示,100% 的受访者睡眠质量较差、有晨起时间型和较好的饮食习惯。大多数受访者(81%)的体育锻炼水平较低,社会支持水平较低(60%),IDH 水平一般(36.1%)。双变量分析表明,睡眠质量和时间型与 IDH 呈负相关。饮食习惯和社会支持与 IDH 呈中度正相关。体育锻炼与 IDH 的关系不大。回归分析显示,睡眠质量、饮食习惯和社会支持这三个变量与 IDH 有明显的相关性。如果将年龄、性别、大学、年级、家庭收入、体重指数和平均成绩都考虑在内,健康科学专业学生的 IDH 没有明显差异。这项研究表明,睡眠质量、饮食习惯和社会支持都能预测 IDH,因此在处理 COVID-19 或未来任何流行病对学生的心理影响时都应加以考虑。
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引用次数: 0
Heated tobacco products: Potentials of harm reduction, improvement of indoor air quality and the need for further studies 加热烟草制品:减少危害、改善室内空气质量的潜力和进一步研究的必要性
Pub Date : 2024-04-15 DOI: 10.54645/2024171pwy-56
Aldwin Camance
Air pollution is a major concern in the Philippines, with indoor and outdoor air pollution among the highest causes of mortality in the country. However, the latest regulations deal only with ambient outdoor air pollution. Indoor air pollution is seldom monitored or studied. Most of the official government monitoring data also deal with outdoor air pollution even if Filipinos spend more than 80% of their time indoors. Smoking indoors can be a cause of excess air pollutants in the indoor setting. Heated Tobacco products, newly introduced in the country, have been reported to reduce the harm of exposure to users to air pollutants. We investigated this through the review of 282 studies, research papers, books, and narratives about HTP use and their effects. These studies show reduced release of harmful and potentially harmful compounds (HPHC) in the aerosol and lower concentrations of HPHCs in the indoor environment when using HTPs as compared to tobacco smoke. Short term pre-clinical studies also show a reduction in the biomarkers for potential exposure to these HPHCs and risk calculations have shown a reduction in cancer potencies across populations. While long-term epidemiological studies are still required to determine with finality the risks that HTP use may have, there is already wide agreement in the initial results that the complete switch to HTP use from cigarette smoking presents less risks of harm. The review, however, shows that much has to be studied about the manner by which HTPs can affect indoor air quality in tropical countries such as the Philippines.
空气污染是菲律宾的一个主要问题,室内和室外空气污染是造成菲律宾人死亡的最主要原因。然而,最新的法规只涉及室外环境空气污染。室内空气污染很少受到监测或研究。即使菲律宾人 80% 以上的时间都在室内度过,但大多数政府官方监测数据也只涉及室外空气污染。室内吸烟可能是造成室内空气污染物超标的一个原因。据报道,菲律宾新推出的加热烟草产品可减少使用者暴露于空气污染物的危害。我们通过查阅有关加热烟草制品使用及其影响的 282 项研究、研究论文、书籍和叙述,对此进行了调查。这些研究表明,与烟草烟雾相比,使用 HTP 可减少气溶胶中有害和潜在有害化合物(HPHC)的释放,降低室内环境中 HPHC 的浓度。短期临床前研究也表明,潜在接触这些高有害物质的生物标志物有所减少,风险计算显示,不同人群的癌症发病率也有所降低。虽然仍需要进行长期的流行病学研究,才能最终确定使用 HTP 可能带来的风险,但初步研究结果已经取得广泛共识,即从吸烟完全转为使用 HTP 带来的危害风险较小。不过,审查结果表明,关于 HTP 如何影响菲律宾等热带国家的室内空气质量,还有许多问题需要研究。
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引用次数: 0
Overexpressed yeast Bax inhibitor (Bxi1p/Ybh3p) is a calcium channel in E. coli 过表达的酵母 Bax 抑制剂(Bxi1p/Ybh3p)是大肠杆菌中的钙通道
Pub Date : 2024-02-28 DOI: 10.54645/202417suppmf-87
James Mullin, John Kalhorn, Julia D. Aguiar, Madelyn Crago, Nicholas Mello, Amanda Raffa, Alexander Strakosha, Nicanor Austriaco, O.P.
Human Bax Inhibitor-1 (HsBI-1/TMBIM6) is the founding member of the evolutionary conserved TMBIM superfamily of proteins that share sequence homology within the transmembrane Bax inhibitor-containing motif (TMBIM). Mechanistically, BI-1/TMBIM6 and all the other mammalian TMBIM proteins appear to be involved in the maintenance of calcium homeostasis, and the crystal structure of a bacterial TMBIM protein, BsYetJ, suggests that the protein is a pH-sensitive calcium leak. The budding yeast, Saccharomyces cerevisiae, has a single TMBIM family member (YNL305C) named Bxi1p/Ybh3p. To determine the function Bxi1p/Ybh3p, we overexpressed Bxi1p-GFP in E. coli to interrogate its putative calcium channel function. We show that bacterial cells expressing Bxi1p-GFP are more permeable to calcium than controls. Our data suggests that yeast Bax inhibitor (Bxi1p) is a calcium channel in E. coli, lending support to our proposal that Bxi1p is a bona fide member of the TMBIM family of proteins. Finally, parallel experiments also revealed that the human Bax Inhibitor-1 (HsBI1/TMBIM6) is also a calcium channel in bacteria.
人类 Bax 抑制剂-1(HsBI-1/TMBIM6)是进化保守的 TMBIM 超家族蛋白的创始成员,这些蛋白在跨膜 Bax 抑制剂包含基序(TMBIM)内具有序列同源性。从机理上讲,BI-1/TMBIM6 和所有其他哺乳动物 TMBIM 蛋白似乎都参与了钙平衡的维持,细菌 TMBIM 蛋白 BsYetJ 的晶体结构表明,该蛋白是一种 pH 敏感的钙泄漏蛋白。芽殖酵母(Saccharomyces cerevisiae)有一个名为 Bxi1p/Ybh3p 的 TMBIM 家族成员(YNL305C)。为了确定 Bxi1p/Ybh3p 的功能,我们在大肠杆菌中过表达了 Bxi1p-GFP,以研究其推测的钙通道功能。我们发现,与对照组相比,表达 Bxi1p-GFP 的细菌细胞对钙的通透性更高。我们的数据表明,酵母 Bax 抑制剂(Bxi1p)在大肠杆菌中是一种钙通道,从而支持了我们关于 Bxi1p 是 TMBIM 蛋白家族真正成员的提议。最后,平行实验还发现人类 Bax 抑制剂-1(HsBI1/TMBIM6)在细菌中也是一种钙通道。
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引用次数: 0
Analysis of EEG signals for the detection of epileptic seizures using feature extraction 利用特征提取分析脑电信号以检测癫痫发作
Pub Date : 2024-02-13 DOI: 10.54645/202417supcqp-72
Ravikumar Kandagatla, V. J. Naidu, P.S. Sreenivasa Reddy, Veera Kavya Pandilla, Marriwada Joshitha, Chanamala Rakesh
The electroencephalogram, which tracks electrical signals in the central nervous system, has been extensively used to diagnose epilepsy, which represents a particular sort of brain abnormality. However, developing seizure classification techniques with significantly better precision and reduced complexity remains challenging. The Epileptic Seizure Recognition dataset, which is publicly accessible in the Kaagle and in the machine learning repository, was used to identify seizures. To identify the seizure, we compared six classification methods to determine which one had the highest success rate. The dataset is subsequently divided, trained, and tested in order to categorize it further using six machine learning algorithms: Stochastic Gradient Descent, Logistic Regression, Naïve Bayes, K-Nearest Neighbors Algorithm, Extra Tree Classifier and Decision Tree. When contrasted with alternative techniques, Extra Trees Classifier possesses the highest accuracy results. The algorithm attained a 96 percent success rate.
脑电图可跟踪中枢神经系统中的电信号,已被广泛用于诊断癫痫,癫痫是一种特殊的脑部异常。然而,开发具有更高精度和更低复杂度的癫痫发作分类技术仍具有挑战性。癫痫发作识别数据集用于识别癫痫发作,该数据集可在 Kaagle 和机器学习资料库中公开访问。为了识别癫痫发作,我们比较了六种分类方法,以确定哪种方法的成功率最高。随后对数据集进行划分、训练和测试,以便使用六种机器学习算法进一步分类:随机梯度下降、逻辑回归、奈夫贝叶斯、K-近邻算法、额外树分类器和决策树。与其他技术相比,额外树分类器的准确率最高。该算法的成功率高达 96%。
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引用次数: 0
A single switch high gain multilevel boost converter with switched inductor topology for photovoltaic applications 采用开关电感拓扑结构的光伏应用单开关高增益多电平升压转换器
Pub Date : 2024-02-12 DOI: 10.54645/202417supdwr-69
Akkela Krishnaveni, Rajender Boini
This paper proposes a new transformer-less single-switch high-gain dc-dc converter for solar power systems. The suggested converter is created by supplementing the conventional boost converter with a switched inductor cell plus a voltage multiplier stage. The converter has several benefits, including a high voltage conversion ratio, reduced voltage stress on semiconducting switches and diodes, a reduction in the need for gate drivers because only one switch is used, as well as constant input current to prolong the lifespan of the photovoltaic cell. The analytical waveforms of the recommended converter can be seen in the continuous conduction mode (CCM). The analysis of voltage stress is done. In the presence of parasitic components, increased voltage gain and efficiency were also obtained.The proposed high-gain converter topology is compared to recently published high-gain converter topologies in terms of performance. Using PSIM, a high-gain dc-dc converter's performance is studied and analysed with regard to its low switching voltage stress. The suggested converter is successful in stepping up 20V to 400V at 160W power capacity, while offering a continuous input source current at 95% efficiency.
本文为太阳能发电系统提出了一种新型无变压器单开关高增益直流-直流转换器。所建议的转换器是在传统升压转换器的基础上增加了一个开关电感单元和一个电压倍增器级。这种转换器有几个优点,包括电压转换率高、减少半导体开关和二极管的电压应力、减少对栅极驱动器的需求(因为只使用了一个开关),以及输入电流恒定以延长光伏电池的使用寿命。在连续传导模式(CCM)下,可以看到推荐转换器的分析波形。对电压应力进行了分析。在存在寄生元件的情况下,还获得了更高的电压增益和效率。建议的高增益转换器拓扑与最近发布的高增益转换器拓扑在性能方面进行了比较。利用 PSIM,研究和分析了高增益直流-直流转换器在低开关电压应力方面的性能。所建议的转换器能在 160W 功率容量下成功地将 20V 电压升压至 400V,同时以 95% 的效率提供持续的输入源电流。
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引用次数: 0
Phytochemical content, antioxidant capacity, and in vitro antibacterial activity of bran extracts of Philippine rice (Oryza sativa) cultivars 菲律宾水稻(Oryza sativa)栽培品种麸皮提取物的植物化学成分含量、抗氧化能力和体外抗菌活性
Pub Date : 2024-01-19 DOI: 10.54645/2024171ztj-34
R. Manaois, J. E. Zapater, Amelia Morales, Jay Carl Cacerez
Rice bran is a by-product of the milling process that contains compounds with possible therapeutic properties. However, it is underutilized. This study assessed the phytochemical content, namely free, bound, and total phenolic (TPC), flavonoid (TFC), and anthocyanin (TAC) contents; antioxidant capacity using the 2,2-diphenylpicrylhydrazyl (DPPH) radical scavenging assay; and in vitro antibacterial activity of crude extracts from the bran of six (one white, two red, three black) selected Philippine rice varieties. Cyanidin-3-glucoside (C3G) and trans-ferulic acid (TFA) were quantified through High-Performance Liquid Chromatography. The in vitro antibacterial activities of extracts (0.1, 0.5, and 0.7 g/mL) against the gram-positive food pathogens Staphylococcus aureus and Clostridium perfringens were evaluated by agar well diffusion assay. Of the five samples, the red rice Kamanga recorded the highest free phenolics (121.01 mg gallic acid equivalents (GAE)/g), TFC (90.14 mg rutin hydrate equivalents/g), and DPPH antioxidant capacity (368.23 µmol Trolox equivalents/g). Generally, black brans had higher TAC, especially Ominio (17.81 mg C3G equivalents/g), which also had the highest bound phenolic content (125.6 mg GAE/g). C3G was only detected on black brans, with at least six-fold more in Ominio than in the other tested varieties. Only the extracts from pigmented varieties, except Ominio, displayed inhibitory potential against the food pathogens, implying that C3G is not the major component imparting the inhibitory activity in the black rice varieties. Therefore, pigmented rice brans can be explored as cheap sources of phytochemicals with antioxidant capacities and natural antibacterial agents for the food and pharmaceutical industries.
米糠是碾磨过程中产生的一种副产品,含有可能具有治疗功效的化合物。然而,米糠的利用率却很低。本研究评估了植物化学成分的含量,即游离、结合和总酚(TPC)、类黄酮(TFC)和花青素(TAC)的含量;使用 2,2-二苯基吡啶肼(DPPH)自由基清除试验的抗氧化能力;以及菲律宾六个(一白、二红、三黑)精选稻米品种米糠粗提取物的体外抗菌活性。通过高效液相色谱法对花青素-3-葡萄糖苷(C3G)和反式阿魏酸(TFA)进行了定量分析。琼脂井扩散试验评估了提取物(0.1、0.5 和 0.7 克/毫升)对革兰氏阳性食品病原体金黄色葡萄球菌和产气荚膜梭菌的体外抗菌活性。在五种样品中,红米 Kamanga 的游离酚(121.01 毫克没食子酸当量(GAE)/克)、TFC(90.14 毫克芦丁水合物当量/克)和 DPPH 抗氧化能力(368.23 微摩尔曲环毒素当量/克)最高。一般来说,黑麸皮的 TAC 较高,尤其是 Ominio(17.81 毫克 C3G 当量/克),其结合酚含量也最高(125.6 毫克 GAE/克)。只在黑麸皮中检测到 C3G,Ominio 中的 C3G 至少是其他测试品种的六倍。除 Ominio 外,只有色素品种的提取物对食品病原体具有抑制潜力,这意味着 C3G 并非黑米品种中具有抑制活性的主要成分。因此,色素稻米麸皮可作为具有抗氧化能力和天然抗菌剂的植物化学物质的廉价来源,供食品和制药行业使用。
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