首页 > 最新文献

Current Opinion in Endocrine and Metabolic Research最新文献

英文 中文
Oxysterol-related disorders Oxysterol-related障碍
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-06-25 DOI: 10.1016/j.coemr.2025.100583
Akira Honda , Hajime Ueda , Teruo Miyazaki , Tadashi Ikegami
Recent advances in oxysterol analysis and studies on their molecular targets indicate that oxysterols, enzymatic or non-enzymatic cholesterol derivatives, are active molecules involved in the pathophysiology of various diseases. This review describes and discusses the recent developments in several oxysterol-related disorders, including atherosclerosis, metabolic dysfunction-associated steatotic liver disease, Alzheimer’s disease, multiple sclerosis, and breast and lung cancers. Unlike congenital abnormalities of oxysterol-metabolizing enzymes, such as cerebrotendinous xanthomatosis and hereditary spastic paraplegia type 5, it is often difficult to assess whether altered oxysterol levels in acquired diseases are the cause or the consequence of disease. In addition, oxysterols exert beneficial or deleterious effects on diseases depending on their structures. Despite these limitations, accumulated experimental evidence is beginning to clarify the impact of oxysterols on the pathophysiology of various diseases.
近年来氧甾醇分析及其分子靶点的研究进展表明，氧甾醇作为酶促或非酶促胆固醇衍生物，是参与多种疾病病理生理的活性分子。这篇综述描述并讨论了几种与氧甾醇相关的疾病的最新进展，包括动脉粥样硬化、代谢功能障碍相关的脂肪变性肝病、阿尔茨海默病、多发性硬化症、乳腺癌和肺癌。与先天性的羟甾醇代谢酶异常不同，如脑腱黄瘤病和遗传性痉挛性截瘫5型，通常很难评估获得性疾病中的羟甾醇水平改变是疾病的原因还是结果。此外，氧甾醇根据其结构对疾病产生有益或有害的影响。尽管存在这些局限性，积累的实验证据开始阐明氧化甾醇对各种疾病病理生理的影响。
{"title":"Oxysterol-related disorders","authors":"Akira Honda ,&nbsp;Hajime Ueda ,&nbsp;Teruo Miyazaki ,&nbsp;Tadashi Ikegami","doi":"10.1016/j.coemr.2025.100583","DOIUrl":"10.1016/j.coemr.2025.100583","url":null,"abstract":"<div><div>Recent advances in oxysterol analysis and studies on their molecular targets indicate that oxysterols, enzymatic or non-enzymatic cholesterol derivatives, are active molecules involved in the pathophysiology of various diseases. This review describes and discusses the recent developments in several oxysterol-related disorders, including atherosclerosis, metabolic dysfunction-associated steatotic liver disease, Alzheimer’s disease, multiple sclerosis, and breast and lung cancers. Unlike congenital abnormalities of oxysterol-metabolizing enzymes, such as cerebrotendinous xanthomatosis and hereditary spastic paraplegia type 5, it is often difficult to assess whether altered oxysterol levels in acquired diseases are the cause or the consequence of disease. In addition, oxysterols exert beneficial or deleterious effects on diseases depending on their structures. Despite these limitations, accumulated experimental evidence is beginning to clarify the impact of oxysterols on the pathophysiology of various diseases.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"40 ","pages":"Article 100583"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
25-hydroxycholesterol in inflammation 25-羟基胆固醇在炎症中的作用
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-06-25 DOI: 10.1016/j.coemr.2025.100582
Romeo Carre, Solenne Vigne, Caroline Pot
Oxysterols, biological active oxidized forms of cholesterol, regulate cholesterol metabolism and intracellular cholesterol levels. They have been attributed additional roles during inflammation and recent data have highlighted their implication in human diseases. The oxysterol downstream of cholesterol 25-hydroxylase (Ch25h), 25-Hydroxycholesterol (25-HC), is largely produced during inflammatory processes. 25-HC and its derived oxysterols play critical roles in immune cell chemotaxis, viral replication inhibition, and neuroinflammation. Mechanistically, mitochondrial function, inflammasomes, endoplasmic reticulum stress, cell death, and cellular metabolism are involved. This review aims to bring the latest knowledge about the role of Ch25h-derived oxysterols under inflammatory conditions related to human diseases, specifically autoimmunity, neurological disorders, and cancers.
氧化甾醇是胆固醇的生物活性氧化形式，调节胆固醇代谢和细胞内胆固醇水平。它们被认为在炎症过程中起着额外的作用，最近的数据强调了它们在人类疾病中的意义。胆固醇25-羟化酶（Ch25h）下游的羟甾醇，25-羟基胆固醇（25-HC），在炎症过程中大量产生。25-HC及其衍生的氧甾醇在免疫细胞趋化、病毒复制抑制和神经炎症中发挥关键作用。机制上涉及线粒体功能、炎性小体、内质网应激、细胞死亡和细胞代谢。本文综述了ch25h衍生的氧化甾醇在与人类疾病相关的炎症条件下的作用的最新知识，特别是自身免疫、神经系统疾病和癌症。
{"title":"25-hydroxycholesterol in inflammation","authors":"Romeo Carre,&nbsp;Solenne Vigne,&nbsp;Caroline Pot","doi":"10.1016/j.coemr.2025.100582","DOIUrl":"10.1016/j.coemr.2025.100582","url":null,"abstract":"<div><div>Oxysterols, biological active oxidized forms of cholesterol, regulate cholesterol metabolism and intracellular cholesterol levels. They have been attributed additional roles during inflammation and recent data have highlighted their implication in human diseases. The oxysterol downstream of cholesterol 25-hydroxylase (Ch25h), 25-Hydroxycholesterol (25-HC), is largely produced during inflammatory processes. 25-HC and its derived oxysterols play critical roles in immune cell chemotaxis, viral replication inhibition, and neuroinflammation. Mechanistically, mitochondrial function, inflammasomes, endoplasmic reticulum stress, cell death, and cellular metabolism are involved. This review aims to bring the latest knowledge about the role of Ch25h-derived oxysterols under inflammatory conditions related to human diseases, specifically autoimmunity, neurological disorders, and cancers.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"40 ","pages":"Article 100582"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A revised Oxysterol Hypothesis highlighting the special roles played by 24(S),25-Epoxycholesterol 修正后的氧甾醇假说强调了24(S)，25-环氧胆固醇的特殊作用
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-06-01 DOI: 10.1016/j.coemr.2025.100578
Nicole M. Fenton, Laura J. Sharpe, Andrew J. Brown
First proposed in 1978, the Oxysterol Hypothesis asserted that oxysterols exert feedback regulation on cholesterol synthesis rather than cholesterol itself. We argue for a revised Oxysterol Hypothesis focussing on recent findings regarding one oxysterol in particular. 24(S),25-epoxycholesterol (24,25EC) is synthesised by a shunt in the cholesterol synthesis pathway, in addition to being produced in the brain from a cholesterol precursor by a sterol hydroxylase (CYP46A1). 24,25EC is implicated in biological processes far beyond just cholesterol metabolism, including being an agonist for Smoothened which transduces the signal in the Hedgehog development pathway, and exerting profound effects on immune functions. We discuss how manipulating 24,25EC is of clinical interest in treating a wide range of disorders, including liver diseases, neurological diseases, and cancers.
1978年首次提出的“氧甾醇假说”认为，氧甾醇对胆固醇合成发挥反馈调节作用，而不是胆固醇本身。我们主张修订的羟甾醇假说，重点关注最近的发现，特别是一种羟甾醇。24(S)，25-环氧胆固醇（24,25ec）除了在大脑中由胆固醇前体通过固醇羟化酶（CYP46A1）产生外，还可通过胆固醇合成途径中的分流合成。24,25ec涉及的生物过程远不止胆固醇代谢，包括作为Smoothened的激动剂，在Hedgehog发育途径中传导信号，并对免疫功能产生深远影响。我们讨论了如何操纵24,25ec在治疗包括肝脏疾病、神经系统疾病和癌症在内的广泛疾病方面具有临床意义。
{"title":"A revised Oxysterol Hypothesis highlighting the special roles played by 24(S),25-Epoxycholesterol","authors":"Nicole M. Fenton,&nbsp;Laura J. Sharpe,&nbsp;Andrew J. Brown","doi":"10.1016/j.coemr.2025.100578","DOIUrl":"10.1016/j.coemr.2025.100578","url":null,"abstract":"<div><div>First proposed in 1978, the Oxysterol Hypothesis asserted that oxysterols exert feedback regulation on cholesterol synthesis rather than cholesterol itself. We argue for a revised Oxysterol Hypothesis focussing on recent findings regarding one oxysterol in particular. 24(<em>S</em>),25-epoxycholesterol (24,25EC) is synthesised by a shunt in the cholesterol synthesis pathway, in addition to being produced in the brain from a cholesterol precursor by a sterol hydroxylase (CYP46A1). 24,25EC is implicated in biological processes far beyond just cholesterol metabolism, including being an agonist for Smoothened which transduces the signal in the Hedgehog development pathway, and exerting profound effects on immune functions. We discuss how manipulating 24,25EC is of clinical interest in treating a wide range of disorders, including liver diseases, neurological diseases, and cancers.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"39 ","pages":"Article 100578"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144204145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial board page 编委会页面
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-06-01 DOI: 10.1016/S2451-9650(25)00010-9
{"title":"Editorial board page","authors":"","doi":"10.1016/S2451-9650(25)00010-9","DOIUrl":"10.1016/S2451-9650(25)00010-9","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"39 ","pages":"Article 100579"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adipose tissue-driven inter-organ metabolite crosstalk 脂肪组织驱动的器官间代谢产物串扰
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-04-19 DOI: 10.1016/j.coemr.2025.100577
Carolina Hagberg , Zoi Michailidou
{"title":"Adipose tissue-driven inter-organ metabolite crosstalk","authors":"Carolina Hagberg ,&nbsp;Zoi Michailidou","doi":"10.1016/j.coemr.2025.100577","DOIUrl":"10.1016/j.coemr.2025.100577","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"39 ","pages":"Article 100577"},"PeriodicalIF":0.0,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143923706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial board page 编委会页面
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-03-01 DOI: 10.1016/S2451-9650(25)00005-5
{"title":"Editorial board page","authors":"","doi":"10.1016/S2451-9650(25)00005-5","DOIUrl":"10.1016/S2451-9650(25)00005-5","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100574"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thyroid cancer—Editorial overview 甲状腺癌编辑综述
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-01-25 DOI: 10.1016/j.coemr.2025.100573
Jennifer A Sipos, Vicki E Smith
{"title":"Thyroid cancer—Editorial overview","authors":"Jennifer A Sipos,&nbsp;Vicki E Smith","doi":"10.1016/j.coemr.2025.100573","DOIUrl":"10.1016/j.coemr.2025.100573","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100573"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insights into the role of adipose tissue-derived microRNAs in intercellular communication during cardiometabolic diseases 洞察脂肪组织来源的microrna在心脏代谢疾病期间细胞间通讯中的作用
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-01-22 DOI: 10.1016/j.coemr.2025.100572
Henver S. Brunetta , Stepheny C. de Campos Zani , Gabriel P. Ruiz , Marcelo A. Mori
microRNAs (miRNAs) secreted by the adipose tissue (AT) have gained substantial attention over the last decade. Adipocytes produce and secrete large amounts of miRNAs that, in turn, can mediate physiological processes paracrinally or in distant organs. It is now clear that AT-derived miRNAs are important players in the development of obesity-associated comorbidities. Here, we provide an overview that supports this notion and bring insights into the intricate involvement of AT-derived miRNAs in the pathogenesis of cardiometabolic diseases, discussing some of their far-reaching effects on the liver, heart, vasculature, and other tissues. Moreover, we outline future research directions addressing current gaps in the field which we hope will further advance our comprehension of the role of AT-derived miRNAs.
在过去的十年中，脂肪组织（AT）分泌的microRNAs （miRNAs）获得了大量的关注。脂肪细胞产生并分泌大量的mirna，这些mirna反过来可以介导旁腺或远端器官的生理过程。现在很清楚，at衍生的mirna在肥胖相关合并症的发展中起着重要作用。在这里，我们提供了一个支持这一观点的概述，并带来了at衍生的mirna在心脏代谢疾病发病机制中的复杂参与，讨论了它们对肝脏、心脏、脉管系统和其他组织的一些深远影响。此外，我们概述了未来的研究方向，以解决当前该领域的空白，我们希望这将进一步促进我们对at衍生miRNAs作用的理解。
{"title":"Insights into the role of adipose tissue-derived microRNAs in intercellular communication during cardiometabolic diseases","authors":"Henver S. Brunetta ,&nbsp;Stepheny C. de Campos Zani ,&nbsp;Gabriel P. Ruiz ,&nbsp;Marcelo A. Mori","doi":"10.1016/j.coemr.2025.100572","DOIUrl":"10.1016/j.coemr.2025.100572","url":null,"abstract":"<div><div>microRNAs (miRNAs) secreted by the adipose tissue (AT) have gained substantial attention over the last decade. Adipocytes produce and secrete large amounts of miRNAs that, in turn, can mediate physiological processes paracrinally or in distant organs. It is now clear that AT-derived miRNAs are important players in the development of obesity-associated comorbidities. Here, we provide an overview that supports this notion and bring insights into the intricate involvement of AT-derived miRNAs in the pathogenesis of cardiometabolic diseases, discussing some of their far-reaching effects on the liver, heart, vasculature, and other tissues. Moreover, we outline future research directions addressing current gaps in the field which we hope will further advance our comprehension of the role of AT-derived miRNAs.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100572"},"PeriodicalIF":0.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143378591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endocrine microbiology: A transdisciplinary approach of the human physiology 内分泌微生物学：人体生理学的跨学科方法
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-01-15 DOI: 10.1016/j.coemr.2025.100570
Marc G.J. Feuilloley, Olivier Lesouhaitier
{"title":"Endocrine microbiology: A transdisciplinary approach of the human physiology","authors":"Marc G.J. Feuilloley,&nbsp;Olivier Lesouhaitier","doi":"10.1016/j.coemr.2025.100570","DOIUrl":"10.1016/j.coemr.2025.100570","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100570"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex hormones–Gut microbiome axis: An update of what is known so far 性激素-肠道微生物轴：目前已知的最新进展
Current Opinion in Endocrine and Metabolic Research
Pub Date : 2025-01-11 DOI: 10.1016/j.coemr.2025.100571
Mohamed Zommiti, Marc G.J. Feuilloley
The human gut microbiota is known to be shaped by a wide range of extrinsic factors (geography, lifestyle, sanitation, diet and drugs) and host intrinsic factors (genetics, age, sexual development and sex hormones). The intricate connection between organs, including glands, and different microbiota is well established with emerging evidence linking gut microbiota, composition, diversity and/or function as a key contributor to gut-organ/gland axis signaling. The observed differences in gut microbiota (GM) composition and diversity have led to numerous investigations highlighting the interaction between steroid hormones and the gut microbiome. In this review, we shed the light on how sex steroid hormones may modulate the composition and the function of the gut microbiota and vice-versa, via focusing on a unique crosstalk between these two main actors. We also highlight the role of the gut microbiota in modulating sex steroids signaling along the gut microbiome-sex hormones axis. Altogether, the evidence implies that gonadal steroids and gut microbiota exert a pivotal role in shifting host bacterial action, given the relevance of these factors in directly impacting physiology, metabolism, reproductive efficiency and even in the development of various ailments in both animals and humans.
众所周知，人类肠道微生物群受多种外在因素（地理、生活方式、卫生、饮食和药物）和宿主内在因素（遗传、年龄、性发育和性激素）的影响。包括腺体在内的器官和不同微生物群之间的复杂联系已经很好地建立起来，新的证据表明肠道微生物群、组成、多样性和/或功能是肠道器官/腺体轴信号的关键贡献者。观察到的肠道微生物群（GM）组成和多样性的差异导致了许多强调类固醇激素和肠道微生物群之间相互作用的研究。在这篇综述中，我们揭示了性类固醇激素如何调节肠道微生物群的组成和功能，反之亦然，通过关注这两个主要参与者之间独特的相互作用。我们还强调了肠道微生物群在沿着肠道微生物群-性激素轴调节性类固醇信号中的作用。总之，这些证据表明，性腺类固醇和肠道微生物群在改变宿主细菌行为方面发挥着关键作用，因为这些因素直接影响动物和人类的生理、代谢、生殖效率，甚至各种疾病的发展。
{"title":"Sex hormones–Gut microbiome axis: An update of what is known so far","authors":"Mohamed Zommiti,&nbsp;Marc G.J. Feuilloley","doi":"10.1016/j.coemr.2025.100571","DOIUrl":"10.1016/j.coemr.2025.100571","url":null,"abstract":"<div><div>The human gut microbiota is known to be shaped by a wide range of extrinsic factors (geography, lifestyle, sanitation, diet and drugs) and host intrinsic factors (genetics, age, sexual development and sex hormones). The intricate connection between organs, including glands, and different microbiota is well established with emerging evidence linking gut microbiota, composition, diversity and/or function as a key contributor to gut-organ/gland axis signaling. The observed differences in gut microbiota (GM) composition and diversity have led to numerous investigations highlighting the interaction between steroid hormones and the gut microbiome. In this review, we shed the light on how sex steroid hormones may modulate the composition and the function of the gut microbiota and vice-versa, via focusing on a unique crosstalk between these two main actors. We also highlight the role of the gut microbiota in modulating sex steroids signaling along the gut microbiome-sex hormones axis. Altogether, the evidence implies that gonadal steroids and gut microbiota exert a pivotal role in shifting host bacterial action, given the relevance of these factors in directly impacting physiology, metabolism, reproductive efficiency and even in the development of various ailments in both animals and humans.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100571"},"PeriodicalIF":0.0,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143200765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
类型
全部 化学•材料 生命科学 医学 物理 工程技术 环境•农林 材料科学 地球科学 法学 管理学 化学 环境科学与生态学 计算机科学 教育学 经济学 农林科学 人文科学 生物学 数学 物理与天体物理 心理学 综合性期刊 其他 工业工程 理学 历史学 农学 文学 信息工程
数据库
全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley
期刊
Current Opinion in Endocrine and Metabolic Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
﹀
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们：info@booksci.cn
Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1