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Pyogenic granuloma of the hard palate leading to alveolar cleft: a case report. 硬腭化脓性肉芽肿导致牙槽裂:病例报告。
Q2 Medicine Pub Date : 2024-06-01 Epub Date: 2024-06-20 DOI: 10.7181/acfs.2024.00080
Woo Jin Song, Hyun Beom Choi, Min Sung Tak

This case report describes a rare occurrence of pyogenic granuloma (PG) in the hard palate deviating from its typical gingival location that led to the formation of an alveolar cleft. The aggressive growth pattern of the lesion, with atypical progression from a pedunculated nodule to an alveolar cleft, raised concern. The diagnosis was based on magnetic resonance imaging and computed tomography findings, which revealed a tadpole-shaped lesion originating from the midline hard palate. The differential diagnosis included a minor salivary gland tumor. Surgical excision was performed under general anesthesia and resulted in a mucosal defect without nasolabial fistula formation or bone exposure. The palatal defect was packed with oxidized regenerated cellulose and closed with Vicryl Rapide sutures, both of which contributed to the patient's successful outcomes. Our comprehensive approach, extending across the stages of surgical planning, execution, and postoperative care, demonstrated the advantages of a multidisciplinary strategy for the accurate diagnosis and effective treatment of palatal PGs. This report makes a meaningful contribution to the existing literature on common oral lesions by emphasizing the importance of a broad differential diagnosis and a systematic approach to oral pathologies. It also raises clinical awareness of PGs with atypical presentations and the diagnostic challenge that they pose.

本病例报告描述了一起罕见的硬腭化脓性肉芽肿(PG)病例,该病例偏离了其典型的牙龈位置,导致牙槽裂的形成。病变的侵袭性生长模式,以及从蒂状结节到齿槽裂的非典型进展,引起了人们的关注。诊断依据是磁共振成像和计算机断层扫描结果,结果显示病变呈蝌蚪状,起源于硬腭中线。鉴别诊断包括轻微的唾液腺肿瘤。手术切除是在全身麻醉的情况下进行的,术后出现了粘膜缺损,但没有形成鼻唇瘘或骨头暴露。腭部缺损处用氧化再生纤维素填塞,并用 Vicryl Rapide 缝线缝合,这两种方法都有助于患者取得成功。我们的综合方法贯穿了手术计划、实施和术后护理的各个阶段,证明了多学科策略在准确诊断和有效治疗腭PG方面的优势。本报告强调了广泛鉴别诊断和系统治疗口腔病变的重要性,为现有的常见口腔病变文献做出了有意义的贡献。它还提高了临床对表现不典型的腭咽癌及其诊断挑战的认识。
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引用次数: 0
Epidemiology of cleft lip and palate charity mission surgery at Bandung Cleft Lip and Palate Center, Indonesia: a 14-year institutional review. 印度尼西亚万隆唇腭裂中心唇腭裂慈善手术的流行病学:14 年机构回顾。
Q2 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-20 DOI: 10.7181/acfs.2023.00416
Ali Sundoro, Dany Hilmanto, Hardisiswo Soedjana, Ronny Lesmana, Selvy Harianti

Background: The management of cleft lip and palate aims at improving the patient's aesthetic and functional outcomes. Delaying primary repair can disrupt the patient's functional status. Long-term follow-up is essential to evaluate the need for secondary repair or revision surgery. This article presents the epidemiology of cleft lip and palate, including comprehensive patient characteristics, the extent of delay, and secondary repair at our institutional center, the Bandung Cleft Lip and Palate Center, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.

Methods: This retrospective study aimed to determine the epidemiology and recurrence rates of cleft lip and palate at the Bandung Cleft Lip and Palate Center, Indonesia, from January 2007 to December 2021. The inclusion criteria were patients diagnosed with cleft lip and/or palate. Procedures such as labioplasty, palatoplasty, secondary lip and nasal repair, and alveolar bone grafting were performed, and data on recurrence were available.

Results: In total, there were 3,618 patients with cleft lip and palate, with an age range of 12 months to 67 years. The mean age was 4.33 years, and the median age was 1.35 years. Males predominated over females in all cleft types (60.4%), and the cleft lip was on the left side in 1,677 patients (46.4%). Most cases were unilateral (2,531; 70.0%) and complete (2,349; 64.9%), and involved a diagnosis of cleft lip and palate (1,981; 54.8%).

Conclusion: Delayed primary labioplasty can affect daily functioning. Primary repair for patients with cleft lip and palate may be postponed due to limited awareness, socioeconomic factors, inadequate facilities, and varying adherence to treatment guidelines. Despite variations in the timing of primary cleft lip repair (not adhering to the recommended protocol), only 10% of these patients undergo reoperation. Healthcare providers should prioritize the importance of the ideal timing for primary repair in order to optimize physiological function without compromising the aesthetic results.

背景:唇腭裂的治疗旨在改善患者的美观和功能。延迟初次修复可能会影响患者的功能状态。长期随访对于评估二次修复或翻修手术的必要性至关重要。本文介绍了唇腭裂的流行病学,包括患者的综合特征、延迟程度以及我们的机构中心--印尼万隆市帕德雅兰大学医学院万隆唇腭裂中心--的二次修复情况:这项回顾性研究旨在确定印度尼西亚万隆唇腭裂中心在2007年1月至2021年12月期间唇腭裂的流行病学和复发率。纳入标准为确诊为唇裂和/或腭裂的患者。手术包括唇成形术、腭成形术、唇鼻二次修复术和牙槽骨移植术,并提供复发数据:共有 3,618 名唇腭裂患者,年龄从 12 个月到 67 岁不等。平均年龄为 4.33 岁,中位年龄为 1.35 岁。在所有唇腭裂类型中,男性多于女性(60.4%),1,677 名患者的唇裂位于左侧(46.4%)。大多数病例为单侧(2,531;70.0%)和完全性(2,349;64.9%),涉及唇腭裂诊断(1,981;54.8%):结论:延迟初次唇成形术会影响日常功能。结论:唇腭裂患者的初次修复手术可能会因认知有限、社会经济因素、设施不足以及对治疗指南的遵守程度不同而被推迟。尽管唇裂初次修复的时间存在差异(未遵守推荐方案),但这些患者中只有 10%的人接受了再次手术。医疗服务提供者应优先考虑初次修复的理想时机,以便在不影响美观效果的前提下优化生理功能。
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引用次数: 0
Successful replantation of an avulsed frontal scalp through microvascular anastomoses of only one artery and one vein: a case report. 通过仅一根动脉和一根静脉的微血管吻合成功再植撕脱的额头头皮:病例报告。
Q2 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-20 DOI: 10.7181/acfs.2023.00122
Dongjin Kim, Somin Oh, Woo Shik Jeong

Scalp avulsion is a devastating injury. The best possible procedure is replantation. Several successful scalp replantations with anastomoses of several vessels in large defects have been reported. In this report, we present a case of replantation of a large scalp avulsion using revascularizing with only one artery and vein. Despite the initial signs of flap congestion, we could predict the survival of the replanted scalp and terminate the procedure after detecting good perfusion and washout with indocyanine green fluorescence imaging. The procedure was successful following the patient's recovery of sensory and sweating functions without complications such as flap necrosis or infection. Several important factors for successful scalp replantation with positive esthetic and functional outcomes were considered.

头皮撕脱是一种破坏性损伤。最好的手术方法是再植。已有多例成功的头皮再植手术报道,在大面积缺损的头皮上吻合了多条血管。在本报告中,我们介绍了一例仅用一条动脉和静脉进行血管再通的头皮大面积撕脱再植手术。尽管最初出现了皮瓣充血的迹象,但我们可以预测再植头皮的存活率,并在吲哚青绿荧光成像检测到良好的灌注和冲洗后终止了手术。在患者恢复感觉和排汗功能后,手术取得了成功,没有出现皮瓣坏死或感染等并发症。成功进行头皮再植手术并取得良好的美学和功能效果的几个重要因素均在考虑之列。
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引用次数: 0
Sural nerve grafts in subacute facial nerve injuries: a report of two cases. 亚急性面神经损伤的硬脑膜神经移植:两例病例报告。
Q2 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-20 DOI: 10.7181/acfs.2023.00234
Jiwon Jeong, Yongjoon Chang, Kuylhee Kim, Chul Hoon Chung, Soyeon Jung

Because facial nerve injuries affect the quality of life, leaving them untreated can have devastating effects. The number of patients with traumatic and iatrogenic facial nerve paralysis is considerably high. Early detection and prompt treatment during the acute injury phase are crucial, and immediate surgical treatment should be considered when complete facial nerve injury is suspected. Symptom underestimation by patients and clinical misdiagnosis may delay surgical intervention, which may negatively affect outcomes and in some cases, impair the recovery of the injured facial nerve. Here, we report two cases of facial nerve injury that were treated with nerve grafts during the subacute phase. In both cases, subacute facial nerve grafting achieved significant improvements. These cases highlight surgical intervention in the subacute phase using nerve grafts as an appropriate treatment for facial nerve injuries.

由于面神经损伤会影响生活质量,如果不及时治疗,可能会造成毁灭性的后果。外伤性和先天性面神经麻痹的患者人数相当多。急性损伤期的早期发现和及时治疗至关重要,如果怀疑面神经完全损伤,应立即考虑手术治疗。患者对症状估计不足和临床误诊可能会延误手术治疗,从而对治疗效果产生负面影响,在某些情况下还会影响受伤面神经的恢复。在此,我们报告了两例在亚急性期接受神经移植治疗的面神经损伤病例。在这两个病例中,亚急性面神经移植都取得了显著的改善。这些病例凸显了在亚急性期使用神经移植物进行手术干预是治疗面神经损伤的适当方法。
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引用次数: 0
Unexpected postoperative atlantoaxial rotatory subluxation after excision of melanocytic nevi of the head and neck in older children: two case reports and literature review. 大龄儿童头颈部黑素细胞痣切除术后意外出现的寰枢椎旋转脱位:两例病例报告和文献综述。
Q2 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-20 DOI: 10.7181/acfs.2023.00444
Jiwon Kang, Byung Jun Kim

Postoperative atlantoaxial rotatory subluxation (AARS) is a rare complication that develops almost exclusively in children following oropharyngeal and otologic surgeries, proposing that oropharyngeal inflammatory responses and excessive head rotation are responsible factors. However, there have been no reports of AARS after excision of a nevus on the head and neck. Here, we present two cases of AARS following limited head rotation during simple nevus excision. Patient 1, a 9-year-old girl, complained of neck pain and limited range of motion after excision of the nevus on the neck. After 2 months, computed tomography and magnetic resonance imaging finally revealed AARS with a ruptured transverse atlantal ligament. A month of halo traction was required for the treatment. Patient 2, an 11-year-old girl, presented with immediate pain and limited neck extension after tissue expander insertion under the upper chest and excision of the nevus on her left cheek. The diagnosis was promptly made using cervical spine radiography. A cervical collar was applied for 1 month. Both patients recovered without any complications after treatment. This report highlights the importance of suspicion for AARS after surgery regardless of surgical duration or amount of head rotation.

术后寰枢旋转半脱位(AARS)是一种罕见的并发症,几乎只发生在口咽和耳科手术后的儿童身上。然而,目前还没有头颈部痣切除术后发生 AARS 的报道。在此,我们介绍两例在单纯痣切除术中因头部旋转受限而导致 AARS 的病例。患者 1 是一名 9 岁女孩,主诉颈部痣切除术后出现颈部疼痛和活动范围受限。2 个月后,计算机断层扫描和磁共振成像最终显示患者患有寰椎横韧带断裂的 AARS。需要进行一个月的光环牵引治疗。患者 2 是一名 11 岁的女孩,在胸部上部插入组织扩张器并切除左脸颊上的痣后,立即出现疼痛和颈部伸展受限。通过颈椎放射线检查,诊断结果很快就出来了。患者被套上颈圈 1 个月。治疗后,两名患者均痊愈,未出现任何并发症。本报告强调了手术后无论手术时间长短或头部旋转幅度大小,都必须怀疑 AARS 的重要性。
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引用次数: 0
An intercontinental comparison of the influence of smoking on the occurrence of nonsyndromic cleft lip and palate: a meta-analysis and systematic review. 吸烟对非综合征唇腭裂发生影响的洲际比较:荟萃分析和系统综述。
Q2 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-20 DOI: 10.7181/acfs.2023.00437
Madhubari Vathulya, Neetu Singh, Manisha Naithani, Peter Kessler

Background: The influence of smoking on nonsyndromic clefts has been a topic of research for many years. However, few studies have investigated the effect of smoking on causing clefts in different gene pools.

Methods: A meta-analysis was conducted of case-control studies related to smoking. Keywords such as "clefts," "cleft lip," "cleft palate," "orofacial cleft," and "smoking" were used to search the MEDLINE, Embase, and Cochrane databases.

Results: In total, 51 articles were reviewed. The RevMan software was utilized for the analysis, and the Mantel-Haenszel method was employed to pool the odds ratios (ORs) and 95% confidence intervals. Although the overall OR, a measure of the association between exposure and outcome, was higher for smokers than for non-smokers, this association was significantly stronger in individuals from Asia and South America (1.73), and lowest in Europe (1.31). Among active and passive smokers in Asia, the OR was approximately 0.93, indicating an equivalent impact from both types of smoking.

Conclusion: This analysis indirectly suggests that restriction measures targeting both active and passive smoking are crucial in Asia.

背景:多年来,吸烟对非综合征裂隙的影响一直是一个研究课题。然而,很少有研究调查了吸烟对不同基因库中裂隙的影响:方法:对与吸烟有关的病例对照研究进行了荟萃分析。在 MEDLINE、Embase 和 Cochrane 数据库中使用 "裂隙"、"唇裂"、"腭裂"、"口面裂 "和 "吸烟 "等关键词进行检索:结果:共审查了 51 篇文章。采用RevMan软件进行分析,并采用Mantel-Haenszel方法汇总几率比(OR)和95%置信区间。虽然衡量暴露与结果之间关系的总体 OR 值在吸烟者中高于非吸烟者,但这种关系在亚洲和南美洲的个体中明显更强(1.73),而在欧洲最低(1.31)。在亚洲的主动吸烟者和被动吸烟者中,OR 值约为 0.93,表明两种吸烟方式的影响相当:这项分析间接表明,针对主动吸烟和被动吸烟的限制措施在亚洲至关重要。
{"title":"An intercontinental comparison of the influence of smoking on the occurrence of nonsyndromic cleft lip and palate: a meta-analysis and systematic review.","authors":"Madhubari Vathulya, Neetu Singh, Manisha Naithani, Peter Kessler","doi":"10.7181/acfs.2023.00437","DOIUrl":"10.7181/acfs.2023.00437","url":null,"abstract":"<p><strong>Background: </strong>The influence of smoking on nonsyndromic clefts has been a topic of research for many years. However, few studies have investigated the effect of smoking on causing clefts in different gene pools.</p><p><strong>Methods: </strong>A meta-analysis was conducted of case-control studies related to smoking. Keywords such as \"clefts,\" \"cleft lip,\" \"cleft palate,\" \"orofacial cleft,\" and \"smoking\" were used to search the MEDLINE, Embase, and Cochrane databases.</p><p><strong>Results: </strong>In total, 51 articles were reviewed. The RevMan software was utilized for the analysis, and the Mantel-Haenszel method was employed to pool the odds ratios (ORs) and 95% confidence intervals. Although the overall OR, a measure of the association between exposure and outcome, was higher for smokers than for non-smokers, this association was significantly stronger in individuals from Asia and South America (1.73), and lowest in Europe (1.31). Among active and passive smokers in Asia, the OR was approximately 0.93, indicating an equivalent impact from both types of smoking.</p><p><strong>Conclusion: </strong>This analysis indirectly suggests that restriction measures targeting both active and passive smoking are crucial in Asia.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary cutaneous mucinous carcinoma in a periorbital lesion: two case reports and literature review. 眶周病变中的原发性皮肤黏液癌:两例病例报告和文献综述。
Q2 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-20 DOI: 10.7181/acfs.2024.00031
Jun Woo Kim, Sung Eun Kim

Primary cutaneous mucinous carcinoma (PCMC) is a rare malignancy of the sweat glands that most commonly affects the periorbital area. It is characterized by slow growth over a prolonged period, and its morphology can be easily confused with a benign tumor, such as an epidermal cyst. Consequently, many patients experience recurrence after undergoing multiple resections. However, there are few reports concerning the surgical management of PCMC. We present two cases of PCMC originating in the periorbital area. The first case involved a 76-year-old man with a mass measuring 3.0× 1.5 cm that had been increasing in size. The second case was a 61-year-old man with two masses, each measuring 1.0× 1.0 cm, that were also growing. Both patients underwent wide excision with a 5-mm safety margin, which was determined based on the widest view of the cross-section of the mass on the magnetic resonance imaging. Subsequently, based on the intraoperative frozen biopsy results, both patients underwent additional excision with a 5-mm safety margin in only one direction. This report shows that, when determining the surgical margin of PCMC in periorbital area, employing imaging modalities and intraoperative frozen biopsies can be helpful for narrowing the surgical margin.

原发性皮肤黏液癌(PCMC)是一种罕见的汗腺恶性肿瘤,最常见于眶周部位。它的特点是长期缓慢生长,其形态很容易与表皮囊肿等良性肿瘤相混淆。因此,许多患者在接受多次切除手术后仍会复发。然而,有关 PCMC 手术治疗的报道却很少。我们介绍了两例起源于眶周的 PCMC。第一例患者是一名 76 岁的男性,肿块大小为 3.0×1.5 厘米,且不断增大。第二例患者是一名 61 岁的男性,身上有两个肿块,每个大小为 1.0× 1.0 厘米,也在不断增大。根据磁共振成像中肿块横截面最宽的视角,确定了 5 毫米的安全边缘。随后,根据术中冰冻活检结果,两名患者都接受了仅在一个方向留有 5 毫米安全边际的额外切除术。本报告表明,在确定眶周 PCMC 的手术切缘时,采用成像模式和术中冷冻活检有助于缩小手术切缘。
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引用次数: 0
Perioperative management of facial reconstruction surgery in patients with end-stage renal disease undergoing dialysis. 接受透析的终末期肾病患者面部重建手术的围手术期管理。
Q2 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-20 DOI: 10.7181/acfs.2024.00045
Chan Woo Jung, Yong Chan Bae

Background: The rising incidence of dialysis-dependent end-stage renal disease (ESRD) has underscored the need for collaboration between plastic surgeons and nephrologists, particularly concerning preoperative and postoperative management for facial reconstruction. This collaboration is essential due to a scarcity of comprehensive information in this domain.

Methods: A study initiated in January 2015 involved 10 ESRD cases on dialysis undergoing Mohs micrographic surgery for facial skin cancer, followed by reconstructive surgery under general anesthesia. To ensure surgical safety, rigorous measures were enacted, encompassing laboratory testing, nephrology consultations, and preoperative dialysis admission. Throughout surgery, meticulous control was exercised over vital signs, electrolytes, bleeding risk, and pain management (excluding nonsteroidal anti-inflammatory drugs). Postoperative assessments included monitoring flap integrity, hematoma formation, infection, and cardiovascular risk through plasma creatinine levels.

Results: Adherence to the proposed guidelines yielded a notable absence of postoperative wound complications. Postoperative plasma creatinine levels exhibited an average decrease of 1.10 mg/dL compared to preoperative levels, indicating improved renal function. Importantly, no cardiopulmonary complications or 30-day mortality were observed. In ESRD patients, creatinine levels decreased significantly postoperatively compared to the preoperative levels (p< 0.05), indicating favorable outcomes.

Conclusion: The consistent application of guidelines for admission, anesthesia, and surgery yielded robust and stable outcomes across all patients. In particular, the findings support the importance of adjusting dialysis schedules. Despite the limited sample size in this study, these findings underscore the effectiveness of a collaborative and meticulous approach for plastic surgeons performing surgery on dialysis-dependent patients, ensuring successful outcomes.

背景:依赖透析的终末期肾病(ESRD)发病率的上升凸显了整形外科医生和肾病专家之间合作的必要性,尤其是在面部重建的术前和术后管理方面。由于该领域的综合信息匮乏,这种合作至关重要:2015 年 1 月启动的一项研究涉及 10 例正在透析的 ESRD 患者,他们因面部皮肤癌接受了莫氏显微外科手术,随后在全身麻醉下进行了重建手术。为确保手术安全,我们采取了严格的措施,包括实验室检测、肾脏科会诊和术前透析入院。在整个手术过程中,对生命体征、电解质、出血风险和疼痛控制(不包括非甾体类消炎药)进行了严格控制。术后评估包括通过血浆肌酐水平监测皮瓣完整性、血肿形成、感染和心血管风险:结果:遵循建议的指导原则后,术后伤口并发症明显减少。术后血浆肌酐水平比术前平均下降了 1.10 mg/dL,表明肾功能得到了改善。重要的是,没有观察到心肺并发症或 30 天死亡率。在 ESRD 患者中,术后肌酐水平与术前水平相比明显下降(p< 0.05),表明疗效良好:结论:所有患者在入院、麻醉和手术中始终如一地应用指南,可获得稳健而稳定的疗效。特别是,研究结果支持调整透析时间表的重要性。尽管这项研究的样本量有限,但这些发现强调了整形外科医生在为透析依赖型患者实施手术时采用协作和细致方法的有效性,从而确保成功的结果。
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引用次数: 0
The branching patterns and termination points of the facial artery: a cadaveric anatomical study. 面部动脉的分支模式和终止点:尸体解剖研究。
Q2 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-20 DOI: 10.7181/acfs.2024.00038
Vu Hoang Nguyen, Lin Cheng-Kuan, Tuan Anh Nguyen, Trang Huu Ngoc Thao Cai

Background: The facial artery is an important blood vessel responsible for supplying the anterior face. Understanding the branching patterns of the facial artery plays a crucial role in various medical specialties such as plastic surgery, dermatology, and oncology. This knowledge contributes to improving the success rate of facial reconstruction and aesthetic procedures. However, debate continues regarding the classification of facial artery branching patterns in the existing literature.

Methods: We conducted a comprehensive anatomical study, in which we dissected 102 facial arteries from 52 embalmed and formaldehyde-fixed Vietnamese cadavers at the Anatomy Department, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.

Results: Our investigation revealed eight distinct termination points and identified 35 combinations of branching patterns, including seven arterial branching patterns. These termination points included the inferior labial artery, superior labial artery, inferior alar artery, lateral nasal artery, angular artery typical, angular artery running along the lower border of the orbicularis oculi muscle, forehead branch, duplex, and short course (hypoplastic). Notably, the branching patterns of the facial artery displayed marked asymmetry between the left and right sides within the same cadaver.

Conclusion: The considerable variation observed in the branching pattern and termination points of the facial artery makes it challenging to establish a definitive classification system for this vessel. Therefore, it is imperative to develop an anatomical map summarizing the major measurements and geometric features of the facial artery. Surgeons and medical professionals involved in facial surgery and procedures must consider the detailed anatomy and relative positioning of the facial artery to minimize the risk of unexpected complications.

背景:面动脉是供应面部前部的重要血管。了解面部动脉的分支模式在整形外科、皮肤科和肿瘤科等不同医学专业中起着至关重要的作用。这些知识有助于提高面部重建和美容手术的成功率。然而,在现有文献中,关于面部动脉分支模式分类的争论仍在继续:我们进行了一项全面的解剖学研究,在越南胡志明市医药大学解剖系解剖了 52 具经防腐处理和甲醛固定的越南尸体上的 102 条面部动脉:我们的调查发现了八个不同的终止点,并确定了 35 种分支模式组合,包括七种动脉分支模式。这些终止点包括唇下动脉、唇上动脉、耳下动脉、鼻外侧动脉、典型的内眦动脉、沿眼轮匝肌下缘运行的内眦动脉、前额支、二联支和短程(发育不全)。值得注意的是,同一尸体左右两侧面部动脉的分支模式明显不对称:结论:在面动脉的分支模式和终止点方面观察到的巨大差异使得为该血管建立一个明确的分类系统具有挑战性。因此,当务之急是绘制一张解剖图,总结面部动脉的主要测量数据和几何特征。参与面部手术和程序的外科医生和医疗专业人员必须考虑面部动脉的详细解剖结构和相对位置,以最大限度地降低意外并发症的风险。
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引用次数: 0
Distribution of maternal risk factors for orofacial cleft in infants in Indonesia: a multicenter prospective study. 印度尼西亚婴儿口面裂的母亲风险因素分布:一项多中心前瞻性研究。
Q2 Medicine Pub Date : 2024-02-01 Epub Date: 2024-02-20 DOI: 10.7181/acfs.2023.00521
Andi Tajrin, M Ruslin, Muh Irfan Rasul, Nurwahida, Hadira, Husni Mubarak, Katharina Oginawati, Nurul Fahimah, Ikeu Tanziha, Annisa Dwi Damayanti, Utriweni Mukhaiyar, Asri Arumsari, Ida Ayu Astuti, Farah Asnely Putri, Shinta Silvia

Background: The pathogenesis of orofacial cleft (OFC) is multifactorial, involving both genetic and non-genetic factors, the latter of which play a key role in the development of these anomalies. This paper addresses the incidence of OFC in Indonesia, with a focus on identifying and examining the distribution of contributory factors, including parental medical history, pregnancy history, and environmental influences.

Methods: The study was conducted through the collection of primary data. An interdisciplinary research team from Indonesia administered a standardized questionnaire to parents who had children with OFC and who had provided informed consent. The case group comprised 133 children born with cleft lip and/or palate, and the control was 133 noncleft children born full-term. The risk factors associated with OFC anomalies were analyzed using the chi-square test and logistic regression. All statistical analyses were performed using SPSS version 25. A p-value of 0.05 or less was considered to indicate statistical significance.

Results: The study comprised 138 children, of whom 82 were boys (59.4%) and 56 were girls (40.6%). Among them, 45 patients (32.6%) presented with both cleft lip and cleft palate, 25 individuals (18.1%) had a cleft palate only, and 28 patients (20.3%) had a cleft lip only. OFC was found to be significantly associated with a maternal family history of congenital birth defects (p< 0.05), complications during the first trimester (p< 0.05), consumption of local fish (p< 0.05), caffeine intake (p< 0.05), prolonged medication use (p< 0.05), immunization history (p< 0.05), passive smoking (p< 0.05), and X-ray exposure during pregnancy (p< 0.05).

Conclusion: The findings indicate close relationships between the incidence of OFC and maternal medical history, prenatal factors, and environmental influences.

背景:口面裂(OFC)的发病机制是多因素的,涉及遗传和非遗传因素,后者在这些畸形的发展中起着关键作用。本文探讨了印度尼西亚 OFC 的发病率,重点是识别和研究各种致病因素的分布情况,包括父母病史、妊娠史和环境影响:研究通过收集原始数据进行。印度尼西亚的一个跨学科研究小组向有 OFC 患儿并已知情同意的父母发放了一份标准化问卷。病例组包括 133 名出生时患有唇裂和/或腭裂的儿童,对照组为 133 名足月产的非唇裂儿童。采用卡方检验和逻辑回归分析了与 OFC 异常相关的风险因素。所有统计分析均使用 SPSS 25 版本进行。P值小于或等于0.05为统计学意义显著:研究对象包括 138 名儿童,其中男孩 82 名(59.4%),女孩 56 名(40.6%)。其中,45 名儿童(32.6%)同时患有唇裂和腭裂,25 名儿童(18.1%)仅患有腭裂,28 名儿童(20.3%)仅患有唇裂。研究发现,唇裂和腭裂与母亲家族先天性出生缺陷病史(p< 0.05)、妊娠头三个月的并发症(p< 0.05)、食用本地鱼类(p< 0.05)、咖啡因摄入量(p< 0.05)、长期用药(p< 0.05)、免疫接种史(p< 0.05)、被动吸烟(p< 0.05)和妊娠期X射线照射(p< 0.05)有明显关系:结论:研究结果表明,OFC 的发病率与母亲的病史、产前因素和环境影响密切相关。
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引用次数: 0
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Archives of Craniofacial Surgery
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