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In vitro comparison of the leakage of carbon dioxide and iodine contrast media in a bleeding model. 二氧化碳和碘造影剂在出血模型中的体外渗漏比较。
IF 1.2 Pub Date : 2024-05-10 DOI: 10.1186/s42155-024-00457-3
Ryoichi Kitamura, Kazuhiro Yoshida, Takaaki Maruhashi, Satoshi Tamura, Yutaro Kurihara, Koyo Suzuki, Yasushi Asari

Background: We aimed to compare the hydrodynamic values of carbon dioxide (CO2) and iodine contrast media for bleeding detection using an in vitro model.

Materials and methods: We created a bleeding model with large and small wounds in simulated blood vessels. We connected a syringe to the bleeding model and the blood pressure transducer, filling the circuit with CO2 and iodine contrast media. The syringe's piston was pressed, and the flow rate and intravascular pressure of the CO2 and iodine contrast media leaking from the bleeding model were measured. We compared each leaked contrast medium's volume, sphere-equivalent diameter, and sphere-equivalent area. These values were analyzed to compare the visibility of the leakage objectively.

Results: At a constant flow rate, the intravascular pressure required for the model to leak was lower for the CO2 than that for the iodine contrast medium. The CO2 contrast medium leakage volume, equivalent circle diameter, and equivalent circle area were greater than those of the iodine one. These values indicate higher CO2 visibility during fluoroscopy.

Conclusions: In the bleeding model, a CO2 contrast medium may be more prone to leakage than the iodine one in large and small wounds. Regarding visibility, a CO2 contrast medium may be more likely to detect leakage than an iodine one.

背景:我们旨在利用体外模型比较二氧化碳(CO2)和碘造影剂在出血检测中的流体力学值:我们创建了一个出血模型,在模拟血管上有大伤口和小伤口。我们将注射器连接到出血模型和血压传感器,在回路中注入二氧化碳和碘造影剂。按下注射器的活塞,测量从出血模型中泄漏的二氧化碳和碘造影剂的流速和血管内压力。我们比较了每种泄漏造影剂的体积、球当量直径和球当量面积。我们对这些数值进行了分析,以客观地比较泄漏的可见度:结果:在恒定流速下,二氧化碳造影剂模型泄漏所需的血管内压力低于碘造影剂。二氧化碳造影剂的泄漏量、等效圆直径和等效圆面积均大于碘造影剂。这些数值表明二氧化碳在透视过程中的能见度更高:结论:在出血模型中,二氧化碳造影剂在大伤口和小伤口中可能比碘造影剂更容易渗漏。在能见度方面,二氧化碳造影剂可能比碘造影剂更容易发现渗漏。
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引用次数: 0
Endovascular and percutaneous embolization of a giant post traumatic arteriovenous fistula of inferior epigastric vessels. 上腹下血管巨大创伤后动静脉瘘的血管内和经皮栓塞术。
IF 1.2 Pub Date : 2024-05-06 DOI: 10.1186/s42155-024-00455-5
Venkata Subbaih Arunachalam, Smily Sharma, Jineesh Valakkada, Anoop Ayyappan, Jayakrishnan Radhakrishnan, Santhosh Kumar Kannath

Background: Arteriovenous fistulas involving the anterior abdominal wall can result from trauma. Such fistulas may remain asymptomatic and undetected for a prolonged duration of time. They tend to recruit multiple arterial feeders with remodelling in the feeding arteries, making them challenging to treat.

Case presentation: We discuss a rare case of a 60-year-old male who presented with complaints of a progressive painless swelling in right lower abdomen. There was a history of blunt injury to abdomen at the same site during alleged road traffic accident 3 years ago. On CT angiography, an arteriovenous fistula was localised to the anterior abdominal wall arising predominantly from the right inferior epigastric artery with a giant venous sac and terminating as a tortuous single venous channel into the right external iliac vein. Few other small feeders were also seen arising from branches of right superior epigastric artery along Winslow's pathway. The main challenge in endovascular management of this patient was embolization of a high flow shunt with a large venous sac and multiple arterial feeders. The dominant arterial feeder was embolized using vascular plug. The superficial location of the lesion offered an additional percutaneous window besides endovascular approach. The venous sac was percutaneously accessed and embolized using n-butyl cyanoacrylate after balloon occlusion of outflow vein. On follow up ultrasonographic evaluation at 3 months, near complete thrombosis of the venous sac was achieved.

Conclusions: Traumatic arteriovenous fistulas involving the inferior epigastric vessels are rare clinical entities. CT angiogram and digital subtraction angiography help in the optimal diagnosis and treatment planning. The use of mechanical embolization devices to cause flow arrest offers an opportunity to use liquid embolic agents which offer better percolation within the lesion. Interventional radiology offers an ideal management of these complex high flow fistulas with a good technical success and acceptable safety profile.

背景:涉及前腹壁的动静脉瘘可由外伤引起。此类瘘管可能长期无症状且未被发现。这些瘘管往往有多条动脉供血,供血动脉会发生重塑,因此治疗难度很大:我们讨论的是一例罕见病例,患者为一名 60 岁男性,主诉右下腹部进行性无痛肿胀。患者曾在 3 年前的一起交通事故中腹部同一部位遭受钝伤。CT 血管造影显示,腹壁前部有一条动静脉瘘,主要来自右下腹部动脉和一个巨大的静脉囊,末端是一条迂曲的单静脉通道,进入右髂外静脉。此外,还可以看到一些其他的小支流,这些支流来自右上腹部动脉沿温斯洛路径的分支。对这名患者进行血管内治疗的主要挑战是栓塞具有大静脉囊和多条动脉馈源的高流量分流道。使用血管栓塞术栓塞了主要的动脉馈源。病变位置较浅,除了血管内方法外,还提供了一个额外的经皮窗口。在球囊封堵流出静脉后,经皮进入静脉囊,并使用氰基丙烯酸正丁酯进行栓塞。在 3 个月的超声随访评估中,静脉囊几乎完全血栓形成:结论:上腹下血管外伤性动静脉瘘是一种罕见的临床病例。CT 血管造影和数字减影血管造影有助于最佳诊断和治疗计划的制定。使用机械栓塞装置造成血流阻滞,为使用液体栓塞剂提供了机会,因为液体栓塞剂能更好地渗入病变部位。介入放射学为这些复杂的高流量瘘管提供了理想的治疗方法,技术成功率高,安全性可接受。
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引用次数: 0
ELECT: prospective, randomized trial comparing microvascular plug versus platinum-fibered microcoils for embolization of aneurysm sac side branches before endovascular aortic aneurysm repair ELECT:前瞻性随机试验,比较微血管塞与铂纤维微线圈在血管内主动脉瘤修补术前栓塞动脉瘤囊侧支的效果
IF 1.2 Pub Date : 2024-05-03 DOI: 10.1186/s42155-024-00454-6
Manuela Konert, Andrej Schmidt, Daniela Branzan, Tim Wittig, Dierk Scheinert, Sabine Steiner
Preemptive selective embolization of aneurysm sac side branches (ASSBs) has been proposed to prevent type II endoleak after endovascular aortic aneurysm repair (EVAR). This study aimed to explore if an embolization strategy using microvascular plugs (MVP) reduces intervention time and radiation dose compared to platinum-fibered microcoils. Furthermore, the effectiveness of the devices in occluding the treated artery was assessed. Sixty patients scheduled for EVAR underwent percutaneous preemptive embolization of ASSBs using MVPs or coils after a 1:1 randomization. Follow-up imaging was performed during aortic stentgraft implantation. Overall, 170 ASSBs were successfully occluded (83 arteries by MVPs and 87 by coils) and no acute treatment failure occurred. The mean procedure time was significantly lower in the group treated with MVPs (55 ± 4 min) compared to coil occlusion (67 ± 3 min; p = 0.018), which was paralleled by a numerically lower radiation dose (119 Gy/cm2 vs. 140 Gy/cm2; p = 0.45). No difference was found for contrast agent use (34 ml MVP group vs 35 ml coil group; p = 0.87). At follow-up, reopening of lumbar arteries was seen in nine cases (four after coil embolization; five after MVPs). Both microvascular plugs and coils can be effectively used for preemptive embolization of aneurysm sac side branches before EVAR. Use of plugs offers a benefit in terms of intervention time. ClinicalTrials.gov Identifier: NCT03842930 Registered 15 February 2019.
有人提出对动脉瘤囊侧枝(ASSB)进行先发制人的选择性栓塞,以防止血管内主动脉瘤修补术(EVAR)后发生 II 型内漏。本研究旨在探讨与铂纤维微线圈相比,使用微血管塞(MVP)的栓塞策略是否能减少介入时间和辐射剂量。此外,还评估了这些装置在闭塞治疗动脉方面的效果。经过 1:1 随机分配,60 名计划接受 EVAR 的患者接受了使用 MVP 或线圈对 ASSB 进行的经皮先发制人栓塞术。在植入主动脉支架期间进行了随访成像。总体而言,170 个 ASSB 被成功阻塞(83 条动脉使用 MVP,87 条动脉使用线圈),没有发生急性治疗失败。与线圈闭塞术(67 ± 3 分钟;p = 0.018)相比,MVP 治疗组的平均手术时间明显缩短(55 ± 4 分钟),同时辐射剂量也明显降低(119 Gy/cm2 对 140 Gy/cm2;p = 0.45)。造影剂的使用没有差异(34 毫升 MVP 组对 35 毫升线圈组;P = 0.87)。在随访中,有 9 例腰部动脉再次开放(线圈栓塞后 4 例;MVP 后 5 例)。微血管栓塞和线圈都可以有效地用于 EVAR 前动脉瘤囊侧支的先期栓塞。使用塞子可缩短介入时间。ClinicalTrials.gov Identifier:NCT03842930 注册日期:2019 年 2 月 15 日。
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引用次数: 0
3-year clinical outcomes of A Singapore VenaSeal™ real world post-market evaluation Study (ASVS) for varicose vein ablation 用于静脉曲张消融的 A Singapore VenaSeal™ 真实世界上市后评估研究 (ASVS) 的 3 年临床结果
IF 1.2 Pub Date : 2024-04-27 DOI: 10.1186/s42155-024-00452-8
Tjun Yip Tang, Charyl Jia Qi Yap, Sze Ling Chan, Shereen Xue Yun Soon, Vanessa Bao Xian Khoo, Edward Choke, Tze Tec Chong
Medium-term clinical outcome data are lacking for cyanoacrylate glue (CAG) ablation for symptomatic varicose veins, especially from the Asian population. Aim was to determine the 3-year symptomatic relief gained from using the VenaSeal™ device to close refluxing truncal veins from the Singaporean ASVS prospective registry. The revised Venous Clinical Severity Score (rVCSS) and three quality of life (QoL) questionnaires were completed to assess clinical improvement in venous disease symptoms along with a dedicated patient satisfaction survey. 70 patients (107 limbs; 40 females; mean age of 60.9 ± 13.6 years) were included at 3 years. At 3 years, rVCSS showed sustained improvement from baseline (5.00 to 0.00; p < 0.001) and 51/70 (72.9%) had improvement by at least 2 or more CEAP categories. Freedom from reintervention was 90% and 85.7% patients were extremely satisfied with the treatment outcome. No further reports of further hypersensitivity reactions after one year. The 3-year follow-up results of the ASVS registry demonstrated continued and sustained clinical efficacy with few reinterventions following CAG embolization in Asian patients with chronic venous insufficiency. ClinicalTrials.gov Registration: NCT03893201.
目前尚缺乏氰基丙烯酸酯胶(CAG)消融术治疗症状性静脉曲张的中期临床结果数据,尤其是来自亚洲人群的数据。本研究的目的是根据新加坡ASVS前瞻性登记数据,确定使用VenaSeal™装置闭合反流的躯干静脉3年后症状缓解的情况。患者填写了静脉临床严重程度评分(rVCSS)修订版和三份生活质量(QoL)问卷,以评估静脉疾病症状的临床改善情况,并进行了专门的患者满意度调查。70 名患者(107 条肢体;40 名女性;平均年龄为 60.9 ± 13.6 岁)接受了为期 3 年的治疗。3 年后,rVCSS 与基线相比有持续改善(从 5.00 降至 0.00;p < 0.001),51/70(72.9%)名患者的症状至少改善了 2 个或更多 CEAP 类别。90%的患者无须再次干预,85.7%的患者对治疗效果非常满意。一年后,没有再出现过敏反应的报告。ASVS登记的3年随访结果表明,CAG栓塞术对亚洲慢性静脉功能不全患者具有持续的临床疗效,很少出现再次干预的情况。ClinicalTrials.gov 注册:NCT03893201。
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引用次数: 0
Enhancing precision in vascular embolization: evaluating the effectiveness of the intentional early detachment technique with detachable coils in complex cases. 提高血管栓塞的精确性:评估在复杂病例中使用可拆卸线圈的有意早期分离技术的有效性。
IF 1.2 Pub Date : 2024-04-25 DOI: 10.1186/s42155-024-00453-7
Shojiro Oka, Shigeshi Kohno, Shigeki Arizono, Yasuyuki Onishi, Masaya Fumimoto, Atsushi Yoshida, Reiichi Ishikura, Kumiko Ando
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引用次数: 0
Report of a semi-branched stent-graft to treat a type 1a endoleak after failed EVAR 用半分支支架移植物治疗 EVAR 失败后的 1a 型内漏的报告
IF 1.2 Pub Date : 2024-04-20 DOI: 10.1186/s42155-024-00448-4
Ozan Yazar, ChunYu Wong, Pieter Bartholomeus Salemans, Chrissy van Wely, Ruben Nouwens, Bart van Grinsven, Lee Hans Bouwman
Endovascular techniques are advancing with the change of treatment paradigm for abdominal aortic aneurysms. Fenestrated EVAR (fEVAR) and branched EVAR (bEVAR) are used for complex aortic aneurysm repair. Both fEVAR and bEVAR have their own advantages and disadvantages. Semi-branches are a new feature that attempt to combine the advantages of both fEVAR and bEVAR. We describe the use of a 4-vessel semi-branched EVAR in a failed EVAR case with a type 1a endoleak. The novel feature of semi-branches in custom-made EVAR devices in endovascular aortic treatment following failed EVAR appear to be a feasible option.
随着腹主动脉瘤治疗模式的改变,血管内技术也在不断进步。开孔EVAR(fEVAR)和分支EVAR(bEVAR)被用于复杂主动脉瘤的修复。fEVAR 和 bEVAR 都有各自的优缺点。半分支是一种新的特征,试图将 fEVAR 和 bEVAR 的优点结合起来。我们描述了在一个 1a 型内漏的 EVAR 失败病例中使用 4 血管半分支 EVAR 的情况。在 EVAR 失败后的主动脉内血管治疗中,定制 EVAR 装置中的半分支这一新颖特征似乎是一种可行的选择。
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引用次数: 0
Hepatic artery stenosis following adult liver transplantation: evaluation of different endovascular treatment approaches 成人肝移植后的肝动脉狭窄:评估不同的血管内治疗方法
IF 1.2 Pub Date : 2024-04-20 DOI: 10.1186/s42155-024-00439-5
Sagar V. Desai, Balasubramani Natarajan, Vinit Khanna, Paul Brady
To evaluate the efficacy and safety of hepatic artery interventions (HAI) versus extra-hepatic arterial interventions (EHAI) when managing clinically significant hepatic artery stenosis (HAS) after adult orthotopic liver transplantation. A single-center retrospective cohort analysis was conducted on liver transplant patients who underwent intervention for clinically significant HAS from September 2012 to September 2021. The HAI treatment arm included hepatic artery angioplasty and/or stent placement while the EHAI treatment arm comprised of non-hepatic visceral artery embolization. Primary outcomes included peri-procedural complications and 1-year liver-related deaths. Secondary outcomes included biliary ischemic events, longitudinal trends in liver enzymes and ultrasound parameters pre-and post-intervention. The HAI arm included 21 procedures in 18 patients and the EHAI arm included 27 procedures in 22 patients. There were increased 1-year liver-related deaths (10% [2/21] vs 0% [0/27], p = 0.10) and complications (29% [6/21] vs 4% [1/27], p = 0.015) in the HAI group compared to the EHAI group. Both HAI and EHAI groups exhibited similar improvements in transaminitis including changes of ALT (-72 U/L vs -112.5 U/L, p = 0.60) and AST (-58 U/L vs -48 U/L, p = 0.56) at 1-month post-procedure. Both treatment arms demonstrated increases in post-procedural peak systolic velocity of the hepatic artery distal to the stenosis, while the HAI group also showed significant improvement in resistive indices following the intervention. Direct hepatic artery interventions remain the definitive treatment for clinically significant hepatic artery stenosis; however, non-hepatic visceral artery embolization can be considered a safe alternative intervention in cases of unfavorable hepatic anatomy.
目的:评估在处理成人正位肝移植后临床症状明显的肝动脉狭窄(HAS)时,肝动脉介入治疗(HAI)与肝外动脉介入治疗(EHAI)的有效性和安全性。我们对2012年9月至2021年9月期间因临床症状明显的HAS而接受介入治疗的肝移植患者进行了单中心回顾性队列分析。HAI治疗组包括肝动脉血管成形术和/或支架置入术,而EHAI治疗组包括非肝内脏动脉栓塞术。主要结果包括围手术期并发症和 1 年肝脏相关死亡。次要结果包括胆道缺血性事件、干预前后肝酶和超声参数的纵向变化趋势。HAI治疗组包括18名患者的21次手术,EHAI治疗组包括22名患者的27次手术。与 EHAI 组相比,HAI 组 1 年肝脏相关死亡(10% [2/21] vs 0% [0/27],p = 0.10)和并发症(29% [6/21] vs 4% [1/27],p = 0.015)有所增加。HAI组和EHAI组在转氨酶方面都有相似的改善,包括术后1个月时ALT(-72 U/L vs -112.5 U/L,p = 0.60)和AST(-58 U/L vs -48 U/L,p = 0.56)的变化。两组治疗均显示肝动脉狭窄远端肝动脉术后收缩峰值速度增加,而HAI组在介入治疗后阻力指数也有显著改善。直接肝动脉介入治疗仍是临床上治疗肝动脉明显狭窄的最终方法;然而,在肝脏解剖结构不理想的情况下,非肝内脏动脉栓塞可被视为一种安全的替代介入治疗方法。
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引用次数: 0
Embolisation of a high – flow renal arteriovenous fistula with the use of simultaneous transvenous and transarterial approach and balloon-assisted coil embolization 采用经静脉和经动脉同时入路及球囊辅助线圈栓塞术栓塞高流量肾动静脉瘘
IF 1.2 Pub Date : 2024-04-19 DOI: 10.1186/s42155-024-00451-9
D. Markoutsas, D. Tzavoulis, G. Tsoukalos, I. Ioannidis
Renal arteriovenous fistula (RAVF) is a rare vascular malformation, which can be asymptomatic or may cause hemorrhage, hypokalaemic hypertension, heart failure and hematuria. Endovascular embolization is a minimally invasive method which can preserve renal parenchyma. In our case, balloon assisted coil embolization with simultaneous transvenous and transarterial approach was used. A remodelling balloon, which is routinely used in neurovascular procedures, was chosen in order to eliminate the risk of coil migration and preserve feeding artery and renal parenchyma. We present a case of successful balloon – assisted coil embolization of a high flow renal arteriovenous fistula in a 25-year-old male patient via simultaneous transarterial and transvenous approach with preservation of the feeding artery. Endovascular embolisation is a safe and effective treatment of RAVFs with low risk of complications. Simultaneous transarterial and transvenous coil deployment with the use of a flow control balloon catheter can eliminate the risk of coil migration and coil protrusion into the parent artery with permanent RAVF occlusion and renal parenchyma preservation.
肾动静脉瘘(RAVF)是一种罕见的血管畸形,可无症状,也可引起出血、低血钾性高血压、心力衰竭和血尿。血管内栓塞是一种微创方法,可以保留肾实质。在我们的病例中,采用了经静脉和经动脉同时入路的球囊辅助线圈栓塞术。为了消除线圈移位的风险并保留供血动脉和肾实质,我们选择了在神经血管手术中常规使用的重塑球囊。我们介绍了一例通过经动脉和经静脉同时入路,在保留供血动脉的情况下,成功对一名 25 岁男性患者的高流量肾动静脉瘘进行球囊辅助线圈栓塞的病例。血管内栓塞是一种安全有效的肾动静脉瘘治疗方法,并发症风险低。使用流量控制球囊导管同时经动脉和经静脉部署线圈,可以消除线圈移位和线圈突入母动脉的风险,实现永久性 RAVF 闭塞并保留肾实质。
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引用次数: 0
Removal method of a Supera interwoven stent invaginated during its implantation in endovascular procedure: a case report 血管内手术中 Supera 交织支架植入过程中内陷的移除方法:一份病例报告
IF 1.2 Pub Date : 2024-04-11 DOI: 10.1186/s42155-024-00449-3
Tasuku Kozasa, Masahiko Fujihara, Tomofumi Tsukizawa, Yuko Yazu, Naoko Abe, Ryoki Doami, Yoshiaki Yokoi
Supera interwoven stents (IWS) have a unique interwoven structure; thus, precise stent placement can be challenging as they are prone to elongation, shortening, and invagination. Particularly, invagination limits long-term patency. This proposed method aims to remove invaginated IWS. A 70-year-old man presented with intermittent claudication in his left lower limb. Endovascular therapy was conventionally performed, and a 5.5 × 40 mm IWS was placed after balloon dilatation; however, invagination occurred. The invaginated IWS was successfully removed by a threading 0.014" wire through the outside of the stent strut, and a snare catheter was used to hold it in place from the inside. Then, while still in place, the 0.014" wire and snare catheter were driven into the guiding sheath. This practical and easy approach to remove invaginated IWS from the body relies on the particular structural characteristics.
Supera 交织支架(IWS)具有独特的交织结构;因此,精确放置支架具有挑战性,因为它们容易伸长、缩短和内陷。尤其是内陷会限制支架的长期通畅。本文提出的方法旨在去除内陷的 IWS。一名 70 岁的男性左下肢出现间歇性跛行。他接受了传统的血管内治疗,并在球囊扩张后置入了一个 5.5 × 40 毫米的 IWS;然而,内陷发生了。通过在支架支柱外侧穿入一根 0.014 英寸的导线,成功取出了内陷的 IWS,并用套管导管从内部将其固定。然后,将 0.014 英寸金属丝和套管导管插入导引鞘。这种从体内移除内嵌 IWS 的实用而简便的方法依赖于其特殊的结构特点。
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引用次数: 0
Endovascular retrieval of a migrated contraceptive implant into the pulmonary artery : case report and review of literature 通过血管取回移入肺动脉的避孕植入物:病例报告和文献综述
IF 1.2 Pub Date : 2024-04-06 DOI: 10.1186/s42155-024-00450-w
Rémi Grange, Nicolas Magand, Nathalie Grand, Stéphanie Leroy, Thomas Corsini, Kasra Azarnoush, Sylvain Grange
The migration of contraceptive devices into pulmonary arteries is extremely rare, reported to be 1 in 100,000. A 19-year-old female presented no sensation of a contraceptive implant in her arm which had been placed one year prior. A CT scan confirmed that the implant had migrated into the left lower segmentary pulmonary artery. After a multidisciplinary meeting, an endovascular approach was attempted. Following right femoral venous access, a 8F NeuronMax® introducer was placed into the left pulmonary artery under fluoroscopic guidance. The contraceptive device was removed using a 25-mm loop snare, with a proximal capture technique. The patient was discharged the following day, with no reported complications. In cases of contraceptive device migration, the first medical decision involves deciding between removal or 'watching and waiting'. Previous reports describe two removal options: endovascular or surgical approaches. Fourteen reports have been published, with high technical success and low rates of complications. The loop snare technique is described as the optimal technique for an endovascular approach. Due to their invasive nature, surgical approaches should be reserved for cases of endovascular removal failure, after evaluating risks and benefits.
避孕器械移入肺动脉的情况极为罕见,据报道只有十万分之一。一名 19 岁的女性在一年前将避孕药具植入手臂,当时没有任何感觉。CT 扫描证实,植入物已移入左下段肺动脉。经多学科会诊后,医生尝试采用血管内方法。在右股静脉入路后,在透视引导下将 8F NeuronMax® 导入器置入左肺动脉。使用 25 毫米环形卡环和近端捕捉技术取出了避孕器。患者于次日出院,无并发症报告。在避孕器移位的病例中,首先要做出的医疗决定是取出避孕器还是 "观察等待"。之前的报告介绍了两种移除方案:血管内方法或手术方法。已发表的 14 篇报告中,技术成功率高,并发症发生率低。环形卡环技术被描述为血管内方法的最佳技术。由于手术具有侵入性,因此在评估风险和益处后,应将手术方法保留给血管内移除失败的病例。
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引用次数: 0
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CVIR Endovascular
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