首页 > 最新文献

CVIR Endovascular最新文献

英文 中文
Transfemoral hepatic vein catheterization reduces procedure time in double vein embolization. 经股动脉肝静脉导管术缩短了双静脉栓塞术的手术时间。
IF 1.2 Pub Date : 2024-05-22 DOI: 10.1186/s42155-024-00463-5
Dominik A Steffen, Arash Najafi, Christoph A Binkert

Background: Double vein embolization with simultaneous embolization of the portal and hepatic vein aims to grow the future liver remnant in preparation for major hepatectomy. Transvenous hepatic vein embolization is usually done via a transjugular access. The purpose of this study is to describe the transfemoral approach as an alternative option and to discuss potential advantages.

Results: Twenty-three patients undergoing hepatic vein embolization via a transjugular (n = 10) or transfemoral access (n = 13) were evaluated retrospectively. In all cases the portal vein embolization was done first. All procedures were technically successful. There were no peri-interventional complications. Only two patients were not able to proceed to surgery. Standardized future liver remnant hypertrophy was non-inferior with the transfemoral approach compared to the transjugular route. Procedure time was significantly shorter in the transfemoral access group (40 ± 13 min) compared to the transjugular group (67 ± 13 min, p < 0.001).

Conclusion: Transfemoral hepatic vein embolization is feasible, safe, and faster due to easier catheterization, improved stability, and simpler patient preparation. These findings will need to be validated in larger studies.

背景:同时栓塞门静脉和肝静脉的双静脉栓塞术旨在培植未来的残肝,为大肝切除术做准备。经静脉肝静脉栓塞通常通过经颈静脉入路进行。本研究的目的是描述经股静脉入路作为一种替代选择,并讨论其潜在的优势:对23例经颈静脉(10例)或经股动脉(13例)进行肝静脉栓塞的患者进行了回顾性评估。所有病例都是先进行门静脉栓塞。所有手术在技术上都很成功。没有发生介入周围并发症。只有两名患者无法进行手术。与经颈静脉途径相比,经股动脉途径的标准未来残肝肥大效果并不差。经股动脉入路组的手术时间(40 ± 13 分钟)明显短于经颈静脉入路组(67 ± 13 分钟,P 结论:经股动脉入路组的手术时间明显短于经颈静脉入路组:经股动脉肝静脉栓塞术可行、安全、快捷,因为导管插入更容易、稳定性更好、患者准备更简单。这些发现需要在更大规模的研究中得到验证。
{"title":"Transfemoral hepatic vein catheterization reduces procedure time in double vein embolization.","authors":"Dominik A Steffen, Arash Najafi, Christoph A Binkert","doi":"10.1186/s42155-024-00463-5","DOIUrl":"10.1186/s42155-024-00463-5","url":null,"abstract":"<p><strong>Background: </strong>Double vein embolization with simultaneous embolization of the portal and hepatic vein aims to grow the future liver remnant in preparation for major hepatectomy. Transvenous hepatic vein embolization is usually done via a transjugular access. The purpose of this study is to describe the transfemoral approach as an alternative option and to discuss potential advantages.</p><p><strong>Results: </strong>Twenty-three patients undergoing hepatic vein embolization via a transjugular (n = 10) or transfemoral access (n = 13) were evaluated retrospectively. In all cases the portal vein embolization was done first. All procedures were technically successful. There were no peri-interventional complications. Only two patients were not able to proceed to surgery. Standardized future liver remnant hypertrophy was non-inferior with the transfemoral approach compared to the transjugular route. Procedure time was significantly shorter in the transfemoral access group (40 ± 13 min) compared to the transjugular group (67 ± 13 min, p < 0.001).</p><p><strong>Conclusion: </strong>Transfemoral hepatic vein embolization is feasible, safe, and faster due to easier catheterization, improved stability, and simpler patient preparation. These findings will need to be validated in larger studies.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11111621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transarterial embolization to treat a massive hemothorax during mechanical circulatory support via puncturing of the extracorporeal membrane oxygenation circuit. 通过穿刺体外膜氧合回路,经动脉栓塞治疗机械循环支持期间的大面积血胸。
IF 1.2 Pub Date : 2024-05-21 DOI: 10.1186/s42155-024-00460-8
Ryota Tsushima, Takaaki Maruhashi, Yutaro Kurihara, Takehiro Hashikata, Yasushi Asari

Background: Current guidelines recommend the use of mechanical circulatory support (MCS) for patients with cardiogenic shock that is refractory to medical therapy. Bleeding is the most common complication of MCS. Transarterial embolization (TAE) is often performed to treat this complication, because it is a less invasive hemostatic procedure. However, the TAE option needs to be carefully considered during MCS, as the access route may be limited during MCS.

Case presentation: A man in his 70 s was diagnosed with acute myocardial infarction and underwent percutaneous coronary intervention via venoarterial extracorporeal membrane oxygenation (VA-ECMO) and Impella. During treatment in the intensive care unit, he suffered damage to a branch of the internal thoracic artery during a cardiac drainage procedure, which was subsequently treated via emergency TAE. An ECMO return cannula and an Impella sheath were inserted into the patient's right and left femoral arteries, respectively. An approach from the left brachial artery was selected, and the left internal thoracic artery was embolized. Subsequently, the patient required re-intervention to treat re-bleeding from another artery. Because it was difficult to target the target artery from the brachial one, owing to interference from the Impella catheter, the ECMO circuit near the return cannula was punctured and a guiding sheath was inserted. The ECMO flow and the patient's blood pressure decreased following placement of this guiding sheath. We were thus able to maintain the patient's blood pressure by increasing the infusion fluids and Impella flow, and embolize the target artery using a gelatin sponge to achieve hemostasis.

Conclusion: When TAE is difficult to perform during MCS using an approach from the upper extremities, a lower extremity approach with a sheath inserted into the ECMO circuit may represent a viable alternative.

背景:现行指南建议对药物治疗无效的心源性休克患者使用机械循环支持(MCS)。出血是机械循环支持最常见的并发症。由于经动脉栓塞术(TAE)是一种创伤较小的止血手术,因此通常用于治疗这种并发症。然而,在进行 MCS 时需要仔细考虑经动脉栓塞术的选择,因为在 MCS 期间通路可能会受到限制:一名 70 多岁的男子被诊断为急性心肌梗死,并通过静脉体外膜肺氧合(VA-ECMO)和 Impella 接受了经皮冠状动脉介入治疗。在重症监护室治疗期间,他的胸内动脉分支在心脏引流过程中受损,随后通过急诊 TAE 进行了治疗。ECMO 回流插管和 Impella 鞘分别插入患者的左右股动脉。选择从左肱动脉入路,对左胸内动脉进行栓塞。随后,患者需要再次介入治疗另一条动脉的再出血。由于受到 Impella 导管的干扰,很难从肱动脉锁定目标动脉,因此穿刺了回流插管附近的 ECMO 循环,并插入了一根引导鞘。放置引导鞘后,ECMO 流量和患者血压均有所下降。因此,我们能够通过增加输液和 Impella 流量来维持患者血压,并使用明胶海绵栓塞目标动脉以达到止血目的:结论:当在 MCS 期间使用上肢入路难以实施 TAE 时,将鞘插入 ECMO 循环的下肢入路可能是一种可行的替代方法。
{"title":"Transarterial embolization to treat a massive hemothorax during mechanical circulatory support via puncturing of the extracorporeal membrane oxygenation circuit.","authors":"Ryota Tsushima, Takaaki Maruhashi, Yutaro Kurihara, Takehiro Hashikata, Yasushi Asari","doi":"10.1186/s42155-024-00460-8","DOIUrl":"10.1186/s42155-024-00460-8","url":null,"abstract":"<p><strong>Background: </strong>Current guidelines recommend the use of mechanical circulatory support (MCS) for patients with cardiogenic shock that is refractory to medical therapy. Bleeding is the most common complication of MCS. Transarterial embolization (TAE) is often performed to treat this complication, because it is a less invasive hemostatic procedure. However, the TAE option needs to be carefully considered during MCS, as the access route may be limited during MCS.</p><p><strong>Case presentation: </strong>A man in his 70 s was diagnosed with acute myocardial infarction and underwent percutaneous coronary intervention via venoarterial extracorporeal membrane oxygenation (VA-ECMO) and Impella. During treatment in the intensive care unit, he suffered damage to a branch of the internal thoracic artery during a cardiac drainage procedure, which was subsequently treated via emergency TAE. An ECMO return cannula and an Impella sheath were inserted into the patient's right and left femoral arteries, respectively. An approach from the left brachial artery was selected, and the left internal thoracic artery was embolized. Subsequently, the patient required re-intervention to treat re-bleeding from another artery. Because it was difficult to target the target artery from the brachial one, owing to interference from the Impella catheter, the ECMO circuit near the return cannula was punctured and a guiding sheath was inserted. The ECMO flow and the patient's blood pressure decreased following placement of this guiding sheath. We were thus able to maintain the patient's blood pressure by increasing the infusion fluids and Impella flow, and embolize the target artery using a gelatin sponge to achieve hemostasis.</p><p><strong>Conclusion: </strong>When TAE is difficult to perform during MCS using an approach from the upper extremities, a lower extremity approach with a sheath inserted into the ECMO circuit may represent a viable alternative.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11106222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The status of academic interventional radiologists in Germany with focus on gender disparity: how can we do better? 德国介入放射学术界的现状,重点关注性别差异:我们如何才能做得更好?
IF 1.2 Pub Date : 2024-05-16 DOI: 10.1186/s42155-024-00456-4
Sophia Freya Ulrike Blum, Cornelia Lieselotte Angelika Dewald, Lena Becker, Emona Staudacher, Mareike Franke, Marcus Katoh, Ralf-Thorsten Hoffmann, Stefan Rohde, Philip Marius Paprottka, Frank Wacker, Kerstin Westphalen, Philipp Bruners, Bernhard Gebauer, Marco Das, Wibke Uller

Purpose: The aim was to characterize the framework conditions in academic interventional radiology (IR) in Germany with focus on differences between genders.

Materials and methods: After IRB approval, all members of The German Society for Interventional Radiology and Minimally Invasive Therapy (n = 1,632) were invited to an online survey on work and research. Statistical comparisons were undertaken with the Fisher's exact test, Wilcoxon rank sum test or Pearson's Chi-squared test.

Results: From 267 available questionnaires (general response rate 16.4%), 200 were fully completed. 40% of these (78/200) were involved in research (71% men vs. 29% women, p < 0.01) and eligible for further analysis. Of these, 6% worked part-time (2% vs. 17%, p < 0.05). 90% of the respondents spent less than 25% of their research during their paid working hours, and 41% performed more than 75% of their research during. leisure time. 28% received exemption for research. 88% were (rather) satisfied with their career. One in two participants successfully applied for funding, with higher success rates among male applicants (90% vs. 75%) and respondents with protected research time (93% vs. 80%). Compared to men, women rated their entrance in research as harder (p < 0.05), their research career as more important (p < 0.05), felt less noticed at congresses (93% vs. 53%, p < 0.01), less confident (98% vs. 71%, p < 0.01), and not well connected (77% vs. 36%, p < 0.01).  CONCLUSION: Women and men did research under the same circumstances; however, women were underrepresented. Future programs should generally focus on protected research time and gather female mentors to advance academic IR in Germany.

目的:旨在描述德国介入放射学(IR)学术界的框架条件,重点关注性别差异:经 IRB 批准后,德国介入放射学和微创治疗学会的所有会员(n = 1,632)受邀参加了一项关于工作和研究的在线调查。统计比较采用费雪精确检验、Wilcoxon 秩和检验或 Pearson 方差检验:在现有的 267 份问卷中(总体答复率为 16.4%),有 200 份完整填写。其中 40%(78/200)参与了研究(71% 为男性,29% 为女性,P
{"title":"The status of academic interventional radiologists in Germany with focus on gender disparity: how can we do better?","authors":"Sophia Freya Ulrike Blum, Cornelia Lieselotte Angelika Dewald, Lena Becker, Emona Staudacher, Mareike Franke, Marcus Katoh, Ralf-Thorsten Hoffmann, Stefan Rohde, Philip Marius Paprottka, Frank Wacker, Kerstin Westphalen, Philipp Bruners, Bernhard Gebauer, Marco Das, Wibke Uller","doi":"10.1186/s42155-024-00456-4","DOIUrl":"10.1186/s42155-024-00456-4","url":null,"abstract":"<p><strong>Purpose: </strong>The aim was to characterize the framework conditions in academic interventional radiology (IR) in Germany with focus on differences between genders.</p><p><strong>Materials and methods: </strong>After IRB approval, all members of The German Society for Interventional Radiology and Minimally Invasive Therapy (n = 1,632) were invited to an online survey on work and research. Statistical comparisons were undertaken with the Fisher's exact test, Wilcoxon rank sum test or Pearson's Chi-squared test.</p><p><strong>Results: </strong>From 267 available questionnaires (general response rate 16.4%), 200 were fully completed. 40% of these (78/200) were involved in research (71% men vs. 29% women, p < 0.01) and eligible for further analysis. Of these, 6% worked part-time (2% vs. 17%, p < 0.05). 90% of the respondents spent less than 25% of their research during their paid working hours, and 41% performed more than 75% of their research during. leisure time. 28% received exemption for research. 88% were (rather) satisfied with their career. One in two participants successfully applied for funding, with higher success rates among male applicants (90% vs. 75%) and respondents with protected research time (93% vs. 80%). Compared to men, women rated their entrance in research as harder (p < 0.05), their research career as more important (p < 0.05), felt less noticed at congresses (93% vs. 53%, p < 0.01), less confident (98% vs. 71%, p < 0.01), and not well connected (77% vs. 36%, p < 0.01).  CONCLUSION: Women and men did research under the same circumstances; however, women were underrepresented. Future programs should generally focus on protected research time and gather female mentors to advance academic IR in Germany.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140946388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Benefits and advances of Cone Beam CT use in prostatic artery embolization: review of the literature and pictorial essay. 在前列腺动脉栓塞术中使用锥形束 CT 的好处和进展:文献综述和图文论文。
IF 1.2 Pub Date : 2024-05-15 DOI: 10.1186/s42155-024-00459-1
Nassir Rostambeigi, Daniel Crawford, Jafar Golzarian

Prostatic artery embolization (PAE) has proven to be an efficacious treatment for urinary symptoms of benign prostatic hyperplasia. PAE is performed in a complex and challenging anatomical field which may pose difficulties from procedural standpoint. Cone beam computed tomography (CBCT) has been proposed as an invaluable tool during the PAE procedure. A review of different techniques and advancements, as well as demonstration of CBCT benefits via a pictorial overview of the salient examples is lacking. The techniques of CBCT are discussed herein and the virtual injection technology as an advancement in CBCT is discussed. To show the merits of CBCT in PAE, a pictorial overview of various clinical scenarios is presented where CBCT can be crucial in decision making. These scenarios are aimed at showing different benefits including identification of the origin of the prostatic artery and avoiding non-target embolization. Other benefits may include ensuring complete embolization of entire prostate gland as angiographic appearance alone can be inconclusive if it mimics a severely thickened bladder wall or ensuring adequate embolization of the median lobe to provide relief from "ball-valve" effect. Further examples include verification of embolization of the entire prostate when rare variants or multiple (> 2) arterial feeders are present.

前列腺动脉栓塞术(PAE)已被证明是治疗良性前列腺增生症排尿症状的有效方法。前列腺动脉栓塞术(PAE)是在一个复杂且具有挑战性的解剖区域内进行的,这可能会给手术带来困难。锥形束计算机断层扫描(CBCT)被认为是 PAE 手术过程中的重要工具。目前还缺乏对不同技术和进展的综述,以及通过突出实例的图解概述来展示 CBCT 的优势。本文讨论了 CBCT 技术,并讨论了作为 CBCT 先进技术的虚拟注射技术。为了说明 CBCT 在 PAE 中的优点,本文以图解的方式概述了 CBCT 在决策中起关键作用的各种临床场景。这些场景旨在展示不同的优势,包括识别前列腺动脉的起源和避免非目标栓塞。其他益处还可能包括确保完全栓塞整个前列腺,因为如果模仿严重增厚的膀胱壁,仅靠血管造影外观可能无法得出结论;或确保充分栓塞中叶,以缓解 "球阀 "效应。更多的例子包括在出现罕见变异或多条(大于 2 条)动脉馈源时验证整个前列腺的栓塞情况。
{"title":"Benefits and advances of Cone Beam CT use in prostatic artery embolization: review of the literature and pictorial essay.","authors":"Nassir Rostambeigi, Daniel Crawford, Jafar Golzarian","doi":"10.1186/s42155-024-00459-1","DOIUrl":"10.1186/s42155-024-00459-1","url":null,"abstract":"<p><p>Prostatic artery embolization (PAE) has proven to be an efficacious treatment for urinary symptoms of benign prostatic hyperplasia. PAE is performed in a complex and challenging anatomical field which may pose difficulties from procedural standpoint. Cone beam computed tomography (CBCT) has been proposed as an invaluable tool during the PAE procedure. A review of different techniques and advancements, as well as demonstration of CBCT benefits via a pictorial overview of the salient examples is lacking. The techniques of CBCT are discussed herein and the virtual injection technology as an advancement in CBCT is discussed. To show the merits of CBCT in PAE, a pictorial overview of various clinical scenarios is presented where CBCT can be crucial in decision making. These scenarios are aimed at showing different benefits including identification of the origin of the prostatic artery and avoiding non-target embolization. Other benefits may include ensuring complete embolization of entire prostate gland as angiographic appearance alone can be inconclusive if it mimics a severely thickened bladder wall or ensuring adequate embolization of the median lobe to provide relief from \"ball-valve\" effect. Further examples include verification of embolization of the entire prostate when rare variants or multiple (> 2) arterial feeders are present.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11093965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Common design and data elements on rectal artery embolization for treatment of symptomatic internal hemorrhoidal disease: an interactive systematic review of clinical trials. 直肠动脉栓塞治疗症状性内痔疾病的通用设计和数据要素:临床试验互动式系统回顾。
IF 1.2 Pub Date : 2024-05-11 DOI: 10.1186/s42155-024-00458-2
Samah Morsi, Marisabel Linares Bolsegui, Hassan Kobeissi, Sherief Ghozy, David F Kallmes, Scott R Kelley, Kellie L Mathis, Eric J Dozois, Conor G Loftus, Emily C Bendel, Vincent Vidal, Scott M Thompson

Background: Internal hemorrhoids (IH) is a common medical condition that can result in morbidity secondary to bleeding and discomfort. Treatment for IH has traditionally consisted of dietary and conservative medical management, focal treatments including banding and sclerotherapy or hemorrhoidectomy. Recently, rectal artery embolization (RAE) has been studied as a potential treatment for bleeding predominant IH. We performed a common design and data element analysis of studies that report on RAE.

Materials and methods: We conducted a qualitative systematic literature review for rectal artery embolization (RAE) for symptomatic hemorrhoidal disease. The screening process involved five online databases (PubMed, Embase, Google Scholar, DOAJ, and Scopus). Additionally, ClinicalTrials.gov was examined for active, unpublished completed studies. The initial search yielded 2000 studies, with 15 studies meeting the inclusion criteria after screening and assessment. The included studies comprised one RCT, one case series, one pilot study and 12 cohort studies.

Results: The population analysis revealed a male predominance across all studies, with varying cohort sizes. The baseline Goligher hemorrhoid grade was utilized in 80% of studies. The majority (73.3%) employed a transfemoral approach, and coils were the primary embolic material in 60% of studies, 26.6% were combination of coils and particles, and 6.6% were particles only. Patient selection criteria highlighted RAE's applicability for high surgical risk patients and those with anemia, chronic hematochezia, or treatment-refractory cases. Exclusion criteria emphasized factors such as previous surgeries, colorectal cancer, rectal prolapse, acute hemorrhoidal complications, and contrast allergy. Study designs varied, with cohort studies being the most common (12/15; 80%). Procedural details included the use of metallic coils and detachable micro-coils, with a high technical success rate reported in most studies ranging from 72 to 100%. The follow-up ranged from 1 to 18 months. The majority of studies reported no major immediate or post-procedural complications.

Conclusion: While all studies focused on RAE as a treatment for IH, there was a great degree of heterogeneity among included studies, particularly regarding inclusion criteria, exclusion criteria, outcomes measures and timeframe. Future literature should attempt to standardize these design elements to help facilitate secondary analyses and increase understanding of RAE as a treatment option.

背景:内痔(IH)是一种常见疾病,可因出血和不适而导致发病。传统的内痔治疗方法包括饮食治疗和保守治疗,病灶治疗包括环扎和硬化剂注射或痔切除术。最近,直肠动脉栓塞术(RAE)作为治疗以出血为主的 IH 的一种潜在方法得到了研究。我们对报道 RAE 的研究进行了共同设计和数据元素分析:我们对直肠动脉栓塞术(RAE)治疗症状性痔疮疾病进行了定性系统文献综述。筛选过程涉及五个在线数据库(PubMed、Embase、Google Scholar、DOAJ 和 Scopus)。此外,临床试验网(ClinicalTrials.gov)也对活跃的、未发表的已完成研究进行了检查。初步搜索共获得 2000 项研究,经过筛选和评估,有 15 项研究符合纳入标准。纳入的研究包括一项 RCT、一项病例系列研究、一项试点研究和 12 项队列研究:人群分析显示,所有研究中男性占多数,队列规模各不相同。80%的研究采用了戈利格痔疮基线分级。大多数研究(73.3%)采用经股动脉入路,60%的研究使用线圈作为主要栓塞材料,26.6%的研究使用线圈和微粒组合,6.6%的研究仅使用微粒。患者选择标准强调 RAE 适用于高手术风险患者、贫血患者、慢性血崩患者或治疗难治性病例。排除标准强调了既往手术、结直肠癌、直肠脱垂、急性痔疮并发症和造影剂过敏等因素。研究设计各不相同,以队列研究最为常见(12/15;80%)。手术细节包括使用金属线圈和可拆卸微线圈,大多数研究报告的技术成功率很高,从72%到100%不等。随访时间从 1 个月到 18 个月不等。大多数研究报告称,术中或术后无重大并发症:虽然所有研究都将 RAE 作为治疗 IH 的一种方法,但所纳入的研究之间存在很大程度的异质性,尤其是在纳入标准、排除标准、结果测量和时间范围方面。未来的文献应尝试将这些设计要素标准化,以帮助进行二次分析,并加深对 RAE 作为一种治疗方案的理解。
{"title":"Common design and data elements on rectal artery embolization for treatment of symptomatic internal hemorrhoidal disease: an interactive systematic review of clinical trials.","authors":"Samah Morsi, Marisabel Linares Bolsegui, Hassan Kobeissi, Sherief Ghozy, David F Kallmes, Scott R Kelley, Kellie L Mathis, Eric J Dozois, Conor G Loftus, Emily C Bendel, Vincent Vidal, Scott M Thompson","doi":"10.1186/s42155-024-00458-2","DOIUrl":"10.1186/s42155-024-00458-2","url":null,"abstract":"<p><strong>Background: </strong>Internal hemorrhoids (IH) is a common medical condition that can result in morbidity secondary to bleeding and discomfort. Treatment for IH has traditionally consisted of dietary and conservative medical management, focal treatments including banding and sclerotherapy or hemorrhoidectomy. Recently, rectal artery embolization (RAE) has been studied as a potential treatment for bleeding predominant IH. We performed a common design and data element analysis of studies that report on RAE.</p><p><strong>Materials and methods: </strong>We conducted a qualitative systematic literature review for rectal artery embolization (RAE) for symptomatic hemorrhoidal disease. The screening process involved five online databases (PubMed, Embase, Google Scholar, DOAJ, and Scopus). Additionally, ClinicalTrials.gov was examined for active, unpublished completed studies. The initial search yielded 2000 studies, with 15 studies meeting the inclusion criteria after screening and assessment. The included studies comprised one RCT, one case series, one pilot study and 12 cohort studies.</p><p><strong>Results: </strong>The population analysis revealed a male predominance across all studies, with varying cohort sizes. The baseline Goligher hemorrhoid grade was utilized in 80% of studies. The majority (73.3%) employed a transfemoral approach, and coils were the primary embolic material in 60% of studies, 26.6% were combination of coils and particles, and 6.6% were particles only. Patient selection criteria highlighted RAE's applicability for high surgical risk patients and those with anemia, chronic hematochezia, or treatment-refractory cases. Exclusion criteria emphasized factors such as previous surgeries, colorectal cancer, rectal prolapse, acute hemorrhoidal complications, and contrast allergy. Study designs varied, with cohort studies being the most common (12/15; 80%). Procedural details included the use of metallic coils and detachable micro-coils, with a high technical success rate reported in most studies ranging from 72 to 100%. The follow-up ranged from 1 to 18 months. The majority of studies reported no major immediate or post-procedural complications.</p><p><strong>Conclusion: </strong>While all studies focused on RAE as a treatment for IH, there was a great degree of heterogeneity among included studies, particularly regarding inclusion criteria, exclusion criteria, outcomes measures and timeframe. Future literature should attempt to standardize these design elements to help facilitate secondary analyses and increase understanding of RAE as a treatment option.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11088570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140908736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro comparison of the leakage of carbon dioxide and iodine contrast media in a bleeding model. 二氧化碳和碘造影剂在出血模型中的体外渗漏比较。
IF 1.2 Pub Date : 2024-05-10 DOI: 10.1186/s42155-024-00457-3
Ryoichi Kitamura, Kazuhiro Yoshida, Takaaki Maruhashi, Satoshi Tamura, Yutaro Kurihara, Koyo Suzuki, Yasushi Asari

Background: We aimed to compare the hydrodynamic values of carbon dioxide (CO2) and iodine contrast media for bleeding detection using an in vitro model.

Materials and methods: We created a bleeding model with large and small wounds in simulated blood vessels. We connected a syringe to the bleeding model and the blood pressure transducer, filling the circuit with CO2 and iodine contrast media. The syringe's piston was pressed, and the flow rate and intravascular pressure of the CO2 and iodine contrast media leaking from the bleeding model were measured. We compared each leaked contrast medium's volume, sphere-equivalent diameter, and sphere-equivalent area. These values were analyzed to compare the visibility of the leakage objectively.

Results: At a constant flow rate, the intravascular pressure required for the model to leak was lower for the CO2 than that for the iodine contrast medium. The CO2 contrast medium leakage volume, equivalent circle diameter, and equivalent circle area were greater than those of the iodine one. These values indicate higher CO2 visibility during fluoroscopy.

Conclusions: In the bleeding model, a CO2 contrast medium may be more prone to leakage than the iodine one in large and small wounds. Regarding visibility, a CO2 contrast medium may be more likely to detect leakage than an iodine one.

背景:我们旨在利用体外模型比较二氧化碳(CO2)和碘造影剂在出血检测中的流体力学值:我们创建了一个出血模型,在模拟血管上有大伤口和小伤口。我们将注射器连接到出血模型和血压传感器,在回路中注入二氧化碳和碘造影剂。按下注射器的活塞,测量从出血模型中泄漏的二氧化碳和碘造影剂的流速和血管内压力。我们比较了每种泄漏造影剂的体积、球当量直径和球当量面积。我们对这些数值进行了分析,以客观地比较泄漏的可见度:结果:在恒定流速下,二氧化碳造影剂模型泄漏所需的血管内压力低于碘造影剂。二氧化碳造影剂的泄漏量、等效圆直径和等效圆面积均大于碘造影剂。这些数值表明二氧化碳在透视过程中的能见度更高:结论:在出血模型中,二氧化碳造影剂在大伤口和小伤口中可能比碘造影剂更容易渗漏。在能见度方面,二氧化碳造影剂可能比碘造影剂更容易发现渗漏。
{"title":"In vitro comparison of the leakage of carbon dioxide and iodine contrast media in a bleeding model.","authors":"Ryoichi Kitamura, Kazuhiro Yoshida, Takaaki Maruhashi, Satoshi Tamura, Yutaro Kurihara, Koyo Suzuki, Yasushi Asari","doi":"10.1186/s42155-024-00457-3","DOIUrl":"10.1186/s42155-024-00457-3","url":null,"abstract":"<p><strong>Background: </strong>We aimed to compare the hydrodynamic values of carbon dioxide (CO<sub>2</sub>) and iodine contrast media for bleeding detection using an in vitro model.</p><p><strong>Materials and methods: </strong>We created a bleeding model with large and small wounds in simulated blood vessels. We connected a syringe to the bleeding model and the blood pressure transducer, filling the circuit with CO<sub>2</sub> and iodine contrast media. The syringe's piston was pressed, and the flow rate and intravascular pressure of the CO<sub>2</sub> and iodine contrast media leaking from the bleeding model were measured. We compared each leaked contrast medium's volume, sphere-equivalent diameter, and sphere-equivalent area. These values were analyzed to compare the visibility of the leakage objectively.</p><p><strong>Results: </strong>At a constant flow rate, the intravascular pressure required for the model to leak was lower for the CO<sub>2</sub> than that for the iodine contrast medium. The CO<sub>2</sub> contrast medium leakage volume, equivalent circle diameter, and equivalent circle area were greater than those of the iodine one. These values indicate higher CO<sub>2</sub> visibility during fluoroscopy.</p><p><strong>Conclusions: </strong>In the bleeding model, a CO<sub>2</sub> contrast medium may be more prone to leakage than the iodine one in large and small wounds. Regarding visibility, a CO<sub>2</sub> contrast medium may be more likely to detect leakage than an iodine one.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11087413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endovascular and percutaneous embolization of a giant post traumatic arteriovenous fistula of inferior epigastric vessels. 上腹下血管巨大创伤后动静脉瘘的血管内和经皮栓塞术。
IF 1.2 Pub Date : 2024-05-06 DOI: 10.1186/s42155-024-00455-5
Venkata Subbaih Arunachalam, Smily Sharma, Jineesh Valakkada, Anoop Ayyappan, Jayakrishnan Radhakrishnan, Santhosh Kumar Kannath

Background: Arteriovenous fistulas involving the anterior abdominal wall can result from trauma. Such fistulas may remain asymptomatic and undetected for a prolonged duration of time. They tend to recruit multiple arterial feeders with remodelling in the feeding arteries, making them challenging to treat.

Case presentation: We discuss a rare case of a 60-year-old male who presented with complaints of a progressive painless swelling in right lower abdomen. There was a history of blunt injury to abdomen at the same site during alleged road traffic accident 3 years ago. On CT angiography, an arteriovenous fistula was localised to the anterior abdominal wall arising predominantly from the right inferior epigastric artery with a giant venous sac and terminating as a tortuous single venous channel into the right external iliac vein. Few other small feeders were also seen arising from branches of right superior epigastric artery along Winslow's pathway. The main challenge in endovascular management of this patient was embolization of a high flow shunt with a large venous sac and multiple arterial feeders. The dominant arterial feeder was embolized using vascular plug. The superficial location of the lesion offered an additional percutaneous window besides endovascular approach. The venous sac was percutaneously accessed and embolized using n-butyl cyanoacrylate after balloon occlusion of outflow vein. On follow up ultrasonographic evaluation at 3 months, near complete thrombosis of the venous sac was achieved.

Conclusions: Traumatic arteriovenous fistulas involving the inferior epigastric vessels are rare clinical entities. CT angiogram and digital subtraction angiography help in the optimal diagnosis and treatment planning. The use of mechanical embolization devices to cause flow arrest offers an opportunity to use liquid embolic agents which offer better percolation within the lesion. Interventional radiology offers an ideal management of these complex high flow fistulas with a good technical success and acceptable safety profile.

背景:涉及前腹壁的动静脉瘘可由外伤引起。此类瘘管可能长期无症状且未被发现。这些瘘管往往有多条动脉供血,供血动脉会发生重塑,因此治疗难度很大:我们讨论的是一例罕见病例,患者为一名 60 岁男性,主诉右下腹部进行性无痛肿胀。患者曾在 3 年前的一起交通事故中腹部同一部位遭受钝伤。CT 血管造影显示,腹壁前部有一条动静脉瘘,主要来自右下腹部动脉和一个巨大的静脉囊,末端是一条迂曲的单静脉通道,进入右髂外静脉。此外,还可以看到一些其他的小支流,这些支流来自右上腹部动脉沿温斯洛路径的分支。对这名患者进行血管内治疗的主要挑战是栓塞具有大静脉囊和多条动脉馈源的高流量分流道。使用血管栓塞术栓塞了主要的动脉馈源。病变位置较浅,除了血管内方法外,还提供了一个额外的经皮窗口。在球囊封堵流出静脉后,经皮进入静脉囊,并使用氰基丙烯酸正丁酯进行栓塞。在 3 个月的超声随访评估中,静脉囊几乎完全血栓形成:结论:上腹下血管外伤性动静脉瘘是一种罕见的临床病例。CT 血管造影和数字减影血管造影有助于最佳诊断和治疗计划的制定。使用机械栓塞装置造成血流阻滞,为使用液体栓塞剂提供了机会,因为液体栓塞剂能更好地渗入病变部位。介入放射学为这些复杂的高流量瘘管提供了理想的治疗方法,技术成功率高,安全性可接受。
{"title":"Endovascular and percutaneous embolization of a giant post traumatic arteriovenous fistula of inferior epigastric vessels.","authors":"Venkata Subbaih Arunachalam, Smily Sharma, Jineesh Valakkada, Anoop Ayyappan, Jayakrishnan Radhakrishnan, Santhosh Kumar Kannath","doi":"10.1186/s42155-024-00455-5","DOIUrl":"10.1186/s42155-024-00455-5","url":null,"abstract":"<p><strong>Background: </strong>Arteriovenous fistulas involving the anterior abdominal wall can result from trauma. Such fistulas may remain asymptomatic and undetected for a prolonged duration of time. They tend to recruit multiple arterial feeders with remodelling in the feeding arteries, making them challenging to treat.</p><p><strong>Case presentation: </strong>We discuss a rare case of a 60-year-old male who presented with complaints of a progressive painless swelling in right lower abdomen. There was a history of blunt injury to abdomen at the same site during alleged road traffic accident 3 years ago. On CT angiography, an arteriovenous fistula was localised to the anterior abdominal wall arising predominantly from the right inferior epigastric artery with a giant venous sac and terminating as a tortuous single venous channel into the right external iliac vein. Few other small feeders were also seen arising from branches of right superior epigastric artery along Winslow's pathway. The main challenge in endovascular management of this patient was embolization of a high flow shunt with a large venous sac and multiple arterial feeders. The dominant arterial feeder was embolized using vascular plug. The superficial location of the lesion offered an additional percutaneous window besides endovascular approach. The venous sac was percutaneously accessed and embolized using n-butyl cyanoacrylate after balloon occlusion of outflow vein. On follow up ultrasonographic evaluation at 3 months, near complete thrombosis of the venous sac was achieved.</p><p><strong>Conclusions: </strong>Traumatic arteriovenous fistulas involving the inferior epigastric vessels are rare clinical entities. CT angiogram and digital subtraction angiography help in the optimal diagnosis and treatment planning. The use of mechanical embolization devices to cause flow arrest offers an opportunity to use liquid embolic agents which offer better percolation within the lesion. Interventional radiology offers an ideal management of these complex high flow fistulas with a good technical success and acceptable safety profile.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11074072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ELECT: prospective, randomized trial comparing microvascular plug versus platinum-fibered microcoils for embolization of aneurysm sac side branches before endovascular aortic aneurysm repair ELECT:前瞻性随机试验,比较微血管塞与铂纤维微线圈在血管内主动脉瘤修补术前栓塞动脉瘤囊侧支的效果
IF 1.2 Pub Date : 2024-05-03 DOI: 10.1186/s42155-024-00454-6
Manuela Konert, Andrej Schmidt, Daniela Branzan, Tim Wittig, Dierk Scheinert, Sabine Steiner
Preemptive selective embolization of aneurysm sac side branches (ASSBs) has been proposed to prevent type II endoleak after endovascular aortic aneurysm repair (EVAR). This study aimed to explore if an embolization strategy using microvascular plugs (MVP) reduces intervention time and radiation dose compared to platinum-fibered microcoils. Furthermore, the effectiveness of the devices in occluding the treated artery was assessed. Sixty patients scheduled for EVAR underwent percutaneous preemptive embolization of ASSBs using MVPs or coils after a 1:1 randomization. Follow-up imaging was performed during aortic stentgraft implantation. Overall, 170 ASSBs were successfully occluded (83 arteries by MVPs and 87 by coils) and no acute treatment failure occurred. The mean procedure time was significantly lower in the group treated with MVPs (55 ± 4 min) compared to coil occlusion (67 ± 3 min; p = 0.018), which was paralleled by a numerically lower radiation dose (119 Gy/cm2 vs. 140 Gy/cm2; p = 0.45). No difference was found for contrast agent use (34 ml MVP group vs 35 ml coil group; p = 0.87). At follow-up, reopening of lumbar arteries was seen in nine cases (four after coil embolization; five after MVPs). Both microvascular plugs and coils can be effectively used for preemptive embolization of aneurysm sac side branches before EVAR. Use of plugs offers a benefit in terms of intervention time. ClinicalTrials.gov Identifier: NCT03842930 Registered 15 February 2019.
有人提出对动脉瘤囊侧枝(ASSB)进行先发制人的选择性栓塞,以防止血管内主动脉瘤修补术(EVAR)后发生 II 型内漏。本研究旨在探讨与铂纤维微线圈相比,使用微血管塞(MVP)的栓塞策略是否能减少介入时间和辐射剂量。此外,还评估了这些装置在闭塞治疗动脉方面的效果。经过 1:1 随机分配,60 名计划接受 EVAR 的患者接受了使用 MVP 或线圈对 ASSB 进行的经皮先发制人栓塞术。在植入主动脉支架期间进行了随访成像。总体而言,170 个 ASSB 被成功阻塞(83 条动脉使用 MVP,87 条动脉使用线圈),没有发生急性治疗失败。与线圈闭塞术(67 ± 3 分钟;p = 0.018)相比,MVP 治疗组的平均手术时间明显缩短(55 ± 4 分钟),同时辐射剂量也明显降低(119 Gy/cm2 对 140 Gy/cm2;p = 0.45)。造影剂的使用没有差异(34 毫升 MVP 组对 35 毫升线圈组;P = 0.87)。在随访中,有 9 例腰部动脉再次开放(线圈栓塞后 4 例;MVP 后 5 例)。微血管栓塞和线圈都可以有效地用于 EVAR 前动脉瘤囊侧支的先期栓塞。使用塞子可缩短介入时间。ClinicalTrials.gov Identifier:NCT03842930 注册日期:2019 年 2 月 15 日。
{"title":"ELECT: prospective, randomized trial comparing microvascular plug versus platinum-fibered microcoils for embolization of aneurysm sac side branches before endovascular aortic aneurysm repair","authors":"Manuela Konert, Andrej Schmidt, Daniela Branzan, Tim Wittig, Dierk Scheinert, Sabine Steiner","doi":"10.1186/s42155-024-00454-6","DOIUrl":"https://doi.org/10.1186/s42155-024-00454-6","url":null,"abstract":"Preemptive selective embolization of aneurysm sac side branches (ASSBs) has been proposed to prevent type II endoleak after endovascular aortic aneurysm repair (EVAR). This study aimed to explore if an embolization strategy using microvascular plugs (MVP) reduces intervention time and radiation dose compared to platinum-fibered microcoils. Furthermore, the effectiveness of the devices in occluding the treated artery was assessed. Sixty patients scheduled for EVAR underwent percutaneous preemptive embolization of ASSBs using MVPs or coils after a 1:1 randomization. Follow-up imaging was performed during aortic stentgraft implantation. Overall, 170 ASSBs were successfully occluded (83 arteries by MVPs and 87 by coils) and no acute treatment failure occurred. The mean procedure time was significantly lower in the group treated with MVPs (55 ± 4 min) compared to coil occlusion (67 ± 3 min; p = 0.018), which was paralleled by a numerically lower radiation dose (119 Gy/cm2 vs. 140 Gy/cm2; p = 0.45). No difference was found for contrast agent use (34 ml MVP group vs 35 ml coil group; p = 0.87). At follow-up, reopening of lumbar arteries was seen in nine cases (four after coil embolization; five after MVPs). Both microvascular plugs and coils can be effectively used for preemptive embolization of aneurysm sac side branches before EVAR. Use of plugs offers a benefit in terms of intervention time. ClinicalTrials.gov Identifier: NCT03842930 Registered 15 February 2019. ","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140827036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3-year clinical outcomes of A Singapore VenaSeal™ real world post-market evaluation Study (ASVS) for varicose vein ablation 用于静脉曲张消融的 A Singapore VenaSeal™ 真实世界上市后评估研究 (ASVS) 的 3 年临床结果
IF 1.2 Pub Date : 2024-04-27 DOI: 10.1186/s42155-024-00452-8
Tjun Yip Tang, Charyl Jia Qi Yap, Sze Ling Chan, Shereen Xue Yun Soon, Vanessa Bao Xian Khoo, Edward Choke, Tze Tec Chong
Medium-term clinical outcome data are lacking for cyanoacrylate glue (CAG) ablation for symptomatic varicose veins, especially from the Asian population. Aim was to determine the 3-year symptomatic relief gained from using the VenaSeal™ device to close refluxing truncal veins from the Singaporean ASVS prospective registry. The revised Venous Clinical Severity Score (rVCSS) and three quality of life (QoL) questionnaires were completed to assess clinical improvement in venous disease symptoms along with a dedicated patient satisfaction survey. 70 patients (107 limbs; 40 females; mean age of 60.9 ± 13.6 years) were included at 3 years. At 3 years, rVCSS showed sustained improvement from baseline (5.00 to 0.00; p < 0.001) and 51/70 (72.9%) had improvement by at least 2 or more CEAP categories. Freedom from reintervention was 90% and 85.7% patients were extremely satisfied with the treatment outcome. No further reports of further hypersensitivity reactions after one year. The 3-year follow-up results of the ASVS registry demonstrated continued and sustained clinical efficacy with few reinterventions following CAG embolization in Asian patients with chronic venous insufficiency. ClinicalTrials.gov Registration: NCT03893201.
目前尚缺乏氰基丙烯酸酯胶(CAG)消融术治疗症状性静脉曲张的中期临床结果数据,尤其是来自亚洲人群的数据。本研究的目的是根据新加坡ASVS前瞻性登记数据,确定使用VenaSeal™装置闭合反流的躯干静脉3年后症状缓解的情况。患者填写了静脉临床严重程度评分(rVCSS)修订版和三份生活质量(QoL)问卷,以评估静脉疾病症状的临床改善情况,并进行了专门的患者满意度调查。70 名患者(107 条肢体;40 名女性;平均年龄为 60.9 ± 13.6 岁)接受了为期 3 年的治疗。3 年后,rVCSS 与基线相比有持续改善(从 5.00 降至 0.00;p < 0.001),51/70(72.9%)名患者的症状至少改善了 2 个或更多 CEAP 类别。90%的患者无须再次干预,85.7%的患者对治疗效果非常满意。一年后,没有再出现过敏反应的报告。ASVS登记的3年随访结果表明,CAG栓塞术对亚洲慢性静脉功能不全患者具有持续的临床疗效,很少出现再次干预的情况。ClinicalTrials.gov 注册:NCT03893201。
{"title":"3-year clinical outcomes of A Singapore VenaSeal™ real world post-market evaluation Study (ASVS) for varicose vein ablation","authors":"Tjun Yip Tang, Charyl Jia Qi Yap, Sze Ling Chan, Shereen Xue Yun Soon, Vanessa Bao Xian Khoo, Edward Choke, Tze Tec Chong","doi":"10.1186/s42155-024-00452-8","DOIUrl":"https://doi.org/10.1186/s42155-024-00452-8","url":null,"abstract":"Medium-term clinical outcome data are lacking for cyanoacrylate glue (CAG) ablation for symptomatic varicose veins, especially from the Asian population. Aim was to determine the 3-year symptomatic relief gained from using the VenaSeal™ device to close refluxing truncal veins from the Singaporean ASVS prospective registry. The revised Venous Clinical Severity Score (rVCSS) and three quality of life (QoL) questionnaires were completed to assess clinical improvement in venous disease symptoms along with a dedicated patient satisfaction survey. 70 patients (107 limbs; 40 females; mean age of 60.9 ± 13.6 years) were included at 3 years. At 3 years, rVCSS showed sustained improvement from baseline (5.00 to 0.00; p < 0.001) and 51/70 (72.9%) had improvement by at least 2 or more CEAP categories. Freedom from reintervention was 90% and 85.7% patients were extremely satisfied with the treatment outcome. No further reports of further hypersensitivity reactions after one year. The 3-year follow-up results of the ASVS registry demonstrated continued and sustained clinical efficacy with few reinterventions following CAG embolization in Asian patients with chronic venous insufficiency. ClinicalTrials.gov Registration: NCT03893201.","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140798748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing precision in vascular embolization: evaluating the effectiveness of the intentional early detachment technique with detachable coils in complex cases. 提高血管栓塞的精确性:评估在复杂病例中使用可拆卸线圈的有意早期分离技术的有效性。
IF 1.2 Pub Date : 2024-04-25 DOI: 10.1186/s42155-024-00453-7
Shojiro Oka, Shigeshi Kohno, Shigeki Arizono, Yasuyuki Onishi, Masaya Fumimoto, Atsushi Yoshida, Reiichi Ishikura, Kumiko Ando
{"title":"Enhancing precision in vascular embolization: evaluating the effectiveness of the intentional early detachment technique with detachable coils in complex cases.","authors":"Shojiro Oka, Shigeshi Kohno, Shigeki Arizono, Yasuyuki Onishi, Masaya Fumimoto, Atsushi Yoshida, Reiichi Ishikura, Kumiko Ando","doi":"10.1186/s42155-024-00453-7","DOIUrl":"https://doi.org/10.1186/s42155-024-00453-7","url":null,"abstract":"","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140657113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
CVIR Endovascular
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1