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Ultrasonic signal detection based on Fabry-Perot cavity sensor. 基于法布里-珀罗腔传感器的超声信号检测。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2021-04-08 DOI: 10.1186/s42492-021-00074-0
Wu Yang, Chonglei Zhang, Jiaqi Zeng, Wei Song

Acoustic/ultrasonic sensors are devices that can convert mechanical energy into electrical signals. The Fabry-Perot cavity is processed on the end face of the double-clad fiber by a two-photon three-dimensional lithography machine. In this study, the outer diameter of the core cladding was 250 μm, the diameter of the core was 9 μm, and the microcavity sensing unit was only 30 μm. It could measure ultrasonic signals with high precision. The characteristics of the proposed ultrasonic sensor were investigated, and its feasibility was proven through experiments. Its design has a small size and can replace a larger ultrasonic detector device for photoacoustic signal detection. The sensor is applicable to the field of biomedical information technology, including medical diagnosis, photoacoustic endoscopy, and photoacoustic imaging.

声学/超声波传感器是一种能将机械能转换成电信号的装置。利用双光子三维光刻机在双包层光纤端面加工法布里-珀罗腔。在本研究中,芯包层外径为250 μm,芯直径为9 μm,微腔传感单元仅为30 μm。它可以高精度地测量超声波信号。研究了所提出的超声波传感器的特性,并通过实验验证了其可行性。其设计具有体积小,可以代替较大的超声波探测仪进行光声信号检测。该传感器适用于医学诊断、光声内窥镜、光声成像等生物医学信息技术领域。
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引用次数: 2
Recovery of photoacoustic images based on accurate ultrasound positioning. 基于超声精确定位的光声图像恢复。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2021-03-25 DOI: 10.1186/s42492-021-00072-2
Yinhao Pan, Ningbo Chen, Liangjian Liu, Chengbo Liu, Zhiqiang Xu, Jianhui Zhang

Photoacoustic microscopy is an in vivo imaging technology based on the photoacoustic effect. It is widely used in various biomedical studies because it can provide high-resolution images while being label-free, safe, and harmless to biological tissue. Polygon-scanning is an effective scanning method in photoacoustic microscopy that can realize fast imaging of biological tissue with a large field of view. However, in polygon-scanning, fluctuations of the rotating motor speed and the geometric error of the rotating mirror cause image distortions, which seriously affect the photoacoustic-microscopy imaging quality. To improve the image quality of photoacoustic microscopy using polygon-scanning, an image correction method is proposed based on accurate ultrasound positioning. In this method, the photoacoustic and ultrasound imaging data of the sample are simultaneously obtained, and the angle information of each mirror used in the polygon-scanning is extracted from the ultrasonic data to correct the photoacoustic images. Experimental results show that the proposed method can significantly reduce image distortions in photoacoustic microscopy, with the image dislocation offset decreasing from 24.774 to 10.365 μm.

光声显微镜是一种基于光声效应的体内成像技术。由于它可以提供高分辨率的图像,同时又无标签,安全,对生物组织无害,因此被广泛应用于各种生物医学研究。多边形扫描是光声显微镜中一种有效的扫描方法,可以实现生物组织的大视场快速成像。然而,在多边形扫描中,旋转电机转速的波动和旋转镜的几何误差会引起图像畸变,严重影响光声显微镜成像质量。为了提高光声显微镜多边形扫描成像的图像质量,提出了一种基于超声精确定位的图像校正方法。该方法同时获取样品的光声和超声成像数据,并从超声数据中提取用于多边形扫描的各反射镜的角度信息,对光声图像进行校正。实验结果表明,该方法能显著降低光声显微镜下的图像畸变,图像位错偏移从24.774 μm减小到10.365 μm。
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引用次数: 2
Review recent developments in photoacoustic imaging and sensing for nondestructive testing and evaluation. 综述了无损检测与评价中光声成像与传感技术的最新进展。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2021-03-19 DOI: 10.1186/s42492-021-00073-1
Sung-Liang Chen, Chao Tian

Photoacoustic (PA) imaging has been widely used in biomedical research and preclinical studies during the past two decades. It has also been explored for nondestructive testing and evaluation (NDT/E) and for industrial applications. This paper describes the basic principles of PA technology for NDT/E and its applications in recent years. PA technology for NDT/E includes the use of a modulated continuous-wave laser and a pulsed laser for PA wave excitation, PA-generated ultrasonic waves, and all-optical PA wave excitation and detection. PA technology for NDT/E has demonstrated broad applications, including the imaging of railway cracks and defects, the imaging of Li metal batteries, the measurements of the porosity and Young's modulus, the detection of defects and damage in silicon wafers, and a visualization of underdrawings in paintings.

近二十年来,光声成像在生物医学研究和临床前研究中得到了广泛的应用。它也被探索用于无损检测和评估(NDT/E)和工业应用。本文介绍了无损检测/检测中PA技术的基本原理及其近年来的应用情况。用于无损检测/电子检测的PA技术包括使用调制连续波激光器和脉冲激光器进行PA波激发,PA产生的超声波以及全光PA波激发和检测。用于无损检测/电子检测的PA技术已经展示了广泛的应用,包括铁路裂缝和缺陷的成像,锂金属电池的成像,孔隙率和杨氏模量的测量,硅晶片缺陷和损伤的检测,以及绘画中衬里图的可视化。
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引用次数: 2
A language to analyze, describe, and explore collections of visual art. 一种分析、描述和探索视觉艺术收藏的语言。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2021-03-01 DOI: 10.1186/s42492-021-00071-3
Hermann Pflüger

A vast quantity of art in existence today is inaccessible to individuals. If people want to know the different types of art that exist, how individual works are connected, and how works of art are interpreted and discussed in the context of other works, they must utilize means other than simply viewing the art. Therefore, this paper proposes a language to analyze, describe, and explore collections of visual art (LadeCA). LadeCA combines human interpretation and automatic analyses of images, allowing users to assess collections of visual art without viewing every image in them. This paper focuses on the lexical base of LadeCA. It also outlines how collections of visual art can be analyzed, described, and explored using a LadeCA vocabulary. Additionally, the relationship between LadeCA and indexing systems, such as ICONCLASS or AAT, is demonstrated, and ways in which LadeCA and indexing systems can complement each other are highlighted. Video abstract.

今天存在的大量艺术品是个人无法接触到的。如果人们想知道存在的不同类型的艺术,个体作品是如何联系起来的,以及艺术作品是如何在其他作品的背景下被解释和讨论的,他们必须使用不仅仅是观看艺术的手段。因此,本文提出了一种分析、描述和探索视觉艺术收藏的语言(LadeCA)。LadeCA结合了人工解释和图像自动分析,允许用户在不查看每一张图像的情况下评估视觉艺术收藏。本文主要研究LadeCA的词汇基础。它还概述了如何使用LadeCA词汇分析、描述和探索视觉艺术收藏。此外,还演示了LadeCA和索引系统(如ICONCLASS或AAT)之间的关系,并强调了LadeCA和索引系统相互补充的方式。视频摘要。
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引用次数: 5
Improvement in resolution of fiber-laser photoacoustic tomography based on a virtual-point concept. 基于虚点概念的光纤激光光声层析成像分辨率的提高。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2021-02-23 DOI: 10.1186/s42492-021-00070-4
Xue Bai, Xu Li, Jun Ma, Bai-Ou Guan

In this study, a virtual-point concept was introduced into fiber-laser photoacoustic tomography to improve the elevational image resolution. The flexible fiber laser was bent into an arc shape to conform to the ultrasound wavefront, which formed an ultrasound focus at the center of the arc. The synthetic aperture focusing technique was utilized to reconstruct the images; as a result, the elevational resolution particularly within the out-of-focus region was considerably improved compared to the resolution of an image retrieved by multiplexing the PA time-resolved signals with sound velocity. The all-optical fiber-laser photoacoustic tomography system with a high spatial resolution has potential for various applications, including biomedical research and preclinical/clinical diagnosis.

本研究将虚点概念引入光纤激光光声层析成像中,以提高图像的高程分辨率。将柔性光纤激光器弯曲成符合超声波前的圆弧形状,在圆弧中心形成超声聚焦。利用合成孔径聚焦技术对图像进行重构;因此,与将PA时间分辨信号与声速进行多路复用获得的图像分辨率相比,高度分辨率,特别是失焦区域内的高度分辨率得到了显著提高。具有高空间分辨率的全光纤-激光光声断层成像系统具有广泛的应用前景,包括生物医学研究和临床前/临床诊断。
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引用次数: 1
Visual analysis of flow and diffusion of hemolytic agents and hematomas. 溶血剂和血肿的流动和扩散目视分析。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2021-01-30 DOI: 10.1186/s42492-020-00068-4
Yafei Zhu, Mengyao Bao, Miaomiao Jiang, Jincai Chang, Jianzhong Cui

The elimination of intracranial hematomas has received widespread attention and the interactions between hemolytic agents and hematomas have become a hot research topic. In this study, we used the Navier-Stokes equation to describe the flow control equation for hemolytic agents in a tube and used Fick's law and the Maxwell-Stefan diffusion theory to describe the diffusion and mass transfer of hemolytic agents and hematomas. The physical fields and initial boundary conditions were set according to the parametric properties of the fluid and drainage tube. The COMSOL Multiphysics software was used to simulate the streamline distribution of hemolytic agents in a bifurcated drainage tube. Additionally, the diffusion behaviors of the hemolytic agents into hematomas were simulated and visual analysis of coupled multiphysics was performed to realize the digitization and visualization of engineering fluid problems and contribute to the field of medical engineering.

颅内血肿的消除已受到广泛关注,溶血剂与血肿的相互作用已成为研究热点。在本研究中,我们用Navier-Stokes方程来描述溶血剂在管内的流动控制方程,用Fick定律和Maxwell-Stefan扩散理论来描述溶血剂和血肿的扩散和传质。根据流体和引流管的参数特性设置物理场和初始边界条件。采用COMSOL Multiphysics软件模拟溶血剂在分流引流管内的流线分布。同时,模拟溶血剂在血肿中的扩散行为,并进行耦合多物理场可视化分析,实现工程流体问题的数字化和可视化,为医学工程领域做出贡献。
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引用次数: 4
Correction to: Classes of tree-based networks. 更正:基于树的网络的类别。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2021-01-26 DOI: 10.1186/s42492-021-00069-x
Mareike Fischer, Lina Herbst, Michelle Galla, Yangjing Long, Kristina Wicke
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引用次数: 1
High-speed high-resolution laser diode-based photoacoustic microscopy for in vivo microvasculature imaging. 用于体内微血管成像的高速高分辨率激光二极管光声显微镜。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2021-01-11 DOI: 10.1186/s42492-020-00067-5
Xiufeng Li, Victor T C Tsang, Lei Kang, Yan Zhang, Terence T W Wong

Laser diodes (LDs) have been considered as cost-effective and compact excitation sources to overcome the requirement of costly and bulky pulsed laser sources that are commonly used in photoacoustic microscopy (PAM). However, the spatial resolution and/or imaging speed of previously reported LD-based PAM systems have not been optimized simultaneously. In this paper, we developed a high-speed and high-resolution LD-based PAM system using a continuous wave LD, operating at a pulsed mode, with a repetition rate of 30 kHz, as an excitation source. A hybrid scanning mechanism that synchronizes a one-dimensional galvanometer mirror and a two-dimensional motorized stage is applied to achieve a fast imaging capability without signal averaging due to the high signal-to-noise ratio. By optimizing the optical system, a high lateral resolution of 4.8 μm has been achieved. In vivo microvasculature imaging of a mouse ear has been demonstrated to show the high performance of our LD-based PAM system.

激光二极管(ld)被认为是一种经济、紧凑的激励源,克服了光声显微镜(PAM)中常用的昂贵、笨重的脉冲激光源的要求。然而,先前报道的基于ld的PAM系统的空间分辨率和/或成像速度并没有同时优化。在本文中,我们开发了一个高速和高分辨率的基于LD的PAM系统,使用连续波LD,在脉冲模式下工作,重复频率为30 kHz,作为激发源。由于高信噪比,采用了一种同步一维振镜和二维机动平台的混合扫描机构,以实现快速成像能力,而无需信号平均。通过对光学系统的优化,获得了4.8 μm的横向分辨率。小鼠耳朵的体内微血管成像已经证明了我们基于ld的PAM系统的高性能。
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引用次数: 9
Correction to: Spatial weight matrix in dimensionality reduction reconstruction for micro-electromechanical system-based photoacoustic microscopy. 基于微机电系统的光声显微镜降维重建中空间权矩阵的修正。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2020-12-21 DOI: 10.1186/s42492-020-00066-6
Yuanzheng Ma, Chang Lu, Kedi Xiong, Wuyu Zhang, Sihua Yang
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引用次数: 0
Modified distance regularized level set evolution for brain ventricles segmentation. 改进距离正则化水平集进化的脑室分割方法。
4区 计算机科学 Q1 Arts and Humanities Pub Date : 2020-12-07 DOI: 10.1186/s42492-020-00064-8
Thirumagal Jayaraman, Sravan Reddy M, Manjunatha Mahadevappa, Anup Sadhu, Pranab Kumar Dutta

Neurodegenerative disorders are commonly characterized by atrophy of the brain which is caused by neuronal loss. Ventricles are one of the prominent structures in the brain; their shape changes, due to their content, the cerebrospinal fluid. Analyzing the morphological changes of ventricles, aids in the diagnosis of atrophy, for which the region of interest needs to be separated from the background. This study presents a modified distance regularized level set evolution segmentation method, incorporating regional intensity information. The proposed method is implemented for segmenting ventricles from brain images for normal and atrophy subjects of magnetic resonance imaging and computed tomography images. Results of the proposed method were compared with ground truth images and produced sensitivity in the range of 65%-90%, specificity in the range of 98%-99%, and accuracy in the range of 95%-98%. Peak signal to noise ratio and structural similarity index were also used as performance measures for determining segmentation accuracy: 95% and 0.95, respectively. The parameters of level set formulation vary for different datasets. An optimization procedure was followed to fine tune parameters. The proposed method was found to be efficient and robust against noisy images. The proposed method is adaptive and multimodal.

神经退行性疾病通常以神经元丧失引起的脑萎缩为特征。脑室是大脑中最重要的结构之一;它们的形状会改变,因为它们的内容物,脑脊液。分析脑室的形态学变化,有助于诊断萎缩,因为感兴趣的区域需要从背景中分离出来。提出了一种结合区域强度信息的改进距离正则化水平集进化分割方法。该方法用于从磁共振成像和计算机断层成像的正常和萎缩受试者的脑图像中分割脑室。结果表明,该方法的灵敏度为65%-90%,特异度为98%-99%,准确度为95%-98%。峰值信噪比和结构相似指数也作为确定分割精度的性能指标:分别为95%和0.95。对于不同的数据集,水平集公式的参数是不同的。采用优化程序对参数进行微调。结果表明,该方法对噪声图像具有较好的鲁棒性和有效性。该方法具有自适应和多模态的特点。
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引用次数: 2
期刊
Visual Computing for Industry, Biomedicine, and Art
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