Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2021.11.008
Diana Restrepo, Ana M. Zapata-Barco, Juan A. Escobar, David Mejía-Rodríguez, Daniela Parra-Dunoyer, Oscar Vargas, Luis Miguel Vélez, Iris T. Buriticá, Isabel Vélez, Sebastián Estrada, Diego F. Rojas-Gualdrón
Introduction
Suicide is a complex, global public health problem. The Colombian clinical practice guideline provides relevant input for its prevention, diagnosis and treatment. The objective was to evaluate the methodological quality, credibility and applicability of the Colombian clinical practice guideline for suicidal behaviour.
Methods
An academic group of 12 evaluators was established to assess the guide and its recommendations in a standardised way, using the AGREE-II and AGREE-REX instruments. The evaluations were given in the range of 0.0-1.0 with 0.7 as a cut-off point for appropriate quality.
Results
The global assessment of the AGREE-II was greater than 0.7 in the dimensions: “scope and objective” (0.86), “clarity of presentation” (0.89), “applicability” (0.73) and “editorial independence” (0.89). The lowest scores were for “participation of those involved” (0.67) and “rigour in preparation” (0.69). With the AGREE-REX, the results in all dimensions were below 0.70, which indicates lower quality and suitability for use.
Conclusions
The adoption process of the Colombian guideline for suicidal behaviour was a rigorous methodological process, while the practice recommendations were valued as of low applicability due to low support in local evidence. It is necessary to strengthen the generation and synthesis of evidence at the national level to give greater support and applicability to the practice recommendations.
{"title":"Valoración crítica de la guía de práctica clínica colombiana para la prevención, el diagnóstico y el tratamiento de la ideación y/o la conducta suicida (adopción)","authors":"Diana Restrepo, Ana M. Zapata-Barco, Juan A. Escobar, David Mejía-Rodríguez, Daniela Parra-Dunoyer, Oscar Vargas, Luis Miguel Vélez, Iris T. Buriticá, Isabel Vélez, Sebastián Estrada, Diego F. Rojas-Gualdrón","doi":"10.1016/j.rcp.2021.11.008","DOIUrl":"10.1016/j.rcp.2021.11.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Suicide is a complex, global public health problem. The Colombian clinical practice guideline provides relevant input for its prevention, diagnosis and treatment. The objective was to evaluate the methodological quality, credibility and applicability of the Colombian clinical practice guideline for suicidal behaviour.</p></div><div><h3>Methods</h3><p>An academic group of 12 evaluators was established to assess the guide and its recommendations in a standardised way, using the AGREE-II and AGREE-REX instruments. The evaluations were given in the range of 0.0-1.0 with 0.7 as a cut-off point for appropriate quality.</p></div><div><h3>Results</h3><p>The global assessment of the AGREE-II was greater than 0.7 in the dimensions: “scope and objective” (0.86), “clarity of presentation” (0.89), “applicability” (0.73) and “editorial independence” (0.89). The lowest scores were for “participation of those involved” (0.67) and “rigour in preparation” (0.69). With the AGREE-REX, the results in all dimensions were below 0.70, which indicates lower quality and suitability for use.</p></div><div><h3>Conclusions</h3><p>The adoption process of the Colombian guideline for suicidal behaviour was a rigorous methodological process, while the practice recommendations were valued as of low applicability due to low support in local evidence. It is necessary to strengthen the generation and synthesis of evidence at the national level to give greater support and applicability to the practice recommendations.</p></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 85-92"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46742702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2024.02.001
Hernando Santamaría-García
{"title":"La psiquiatría contemporánea y la posibilidad de una nueva neuropsiquiatría","authors":"Hernando Santamaría-García","doi":"10.1016/j.rcp.2024.02.001","DOIUrl":"https://doi.org/10.1016/j.rcp.2024.02.001","url":null,"abstract":"","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 1-2"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140030472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2022.04.002
Adalberto Campo-Arias , Robin Andrés Grubert , Edwin Herazo
{"title":"Implicaciones de la etnia/raza en salud mental pública","authors":"Adalberto Campo-Arias , Robin Andrés Grubert , Edwin Herazo","doi":"10.1016/j.rcp.2022.04.002","DOIUrl":"10.1016/j.rcp.2022.04.002","url":null,"abstract":"","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 3-4"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44286823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2022.04.001
Adalberto Campo-Arias, Mónica Reyes-Rojas
{"title":"Disforia o incongruencia de género: más de lo mismo en la CIE-11 y el DSM-5-TR","authors":"Adalberto Campo-Arias, Mónica Reyes-Rojas","doi":"10.1016/j.rcp.2022.04.001","DOIUrl":"10.1016/j.rcp.2022.04.001","url":null,"abstract":"","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 5-7"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49285093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2021.11.009
Lina Marcela Sandoval , Elvis Siprian Castro , Andrés Fandiño-Losada , Sara Gabriela Pacichana-Quinayaz , Shirley Evelyn Lennon , María Isabel Gutiérrez-Martínez
Background
Violence is an important public health problem and one of the main causes of deaths worldwide. The mental health consequences of surviving intimate partner violence (IPV) include depression, anxiety and post-traumatic stress disorder. Previous studies have identified that there is a relationship between depression and level of disability in female survivors of IPV. Estimating the direct, indirect or total effect of an exposure on an outcome makes it possible to identify mediating effects between a group of variables. Detecting mediation effects is useful for identifying casual pathways that generate a final outcome and provides a rationale for designing interventions to target the mediator, which in turn positively affects the outcome. The objective was to identify the mediating role of depressive symptoms on the relationship between IPV and disability.
Methods
This was a cross-sectional study of 94 women over the age of 18 who were survivors of IPV by men. They were recruited from two public hospitals in Cali and Tuluá in southwest Colombia. An analysis of casual relationships was performed using structural equation modelling that was made up of: four exogenous observed variables (age, current relationship status [in a relationship or single], level of schooling, and history of an impairment), intermediate endogenous variables (violence and depressive symptoms), and the main endogenous variable (disability). The analyses were carried out in Stata14.2.
Results
The direct effect of IPV severity on the level of disability was not statistically significant (β = 0.09; P = 0.63). However, the indirect effect of IPV severity on disability mediated by depressive symptoms was (β = 0.39; P < 0.01). The total effect of IPV severity on the level of disability was even greater (β = 0.48; P = 0.01).
Conclusions
This study found a complete mediating role of depressive symptoms on the relationship between the severity of IPV and the level of disability for the female participants in this study. The results of this research contribute to defining strategies to prevent and address intimate partner violence, depressive symptoms and disability in this population.
{"title":"Violence Exposure and Disability in Colombian Female Survivors of Intimate Partner Violence: the Mediating Role of Depressive Symptoms","authors":"Lina Marcela Sandoval , Elvis Siprian Castro , Andrés Fandiño-Losada , Sara Gabriela Pacichana-Quinayaz , Shirley Evelyn Lennon , María Isabel Gutiérrez-Martínez","doi":"10.1016/j.rcp.2021.11.009","DOIUrl":"https://doi.org/10.1016/j.rcp.2021.11.009","url":null,"abstract":"<div><h3>Background</h3><p>Violence is an important public health problem and one of the main causes of deaths worldwide. The mental health consequences of surviving intimate partner violence (IPV) include depression, anxiety and post-traumatic stress disorder. Previous studies have identified that there is a relationship between depression and level of disability in female survivors of IPV. Estimating the direct, indirect or total effect of an exposure on an outcome makes it possible to identify mediating effects between a group of variables. Detecting mediation effects is useful for identifying casual pathways that generate a final outcome and provides a rationale for designing interventions to target the mediator, which in turn positively affects the outcome. The objective was to identify the mediating role of depressive symptoms on the relationship between IPV and disability.</p></div><div><h3>Methods</h3><p>This was a cross-sectional study of 94 women over the age of 18 who were survivors of IPV by men. They were recruited from two public hospitals in Cali and Tuluá in southwest Colombia. An analysis of casual relationships was performed using structural equation modelling that was made up of: four exogenous observed variables (age, current relationship status [in a relationship or single], level of schooling, and history of an impairment), intermediate endogenous variables (violence and depressive symptoms), and the main endogenous variable (disability). The analyses were carried out in Stata14.2.</p></div><div><h3>Results</h3><p>The direct effect of IPV severity on the level of disability was not statistically significant (β<!--> <!-->=<!--> <!-->0.09; <em>P</em> <!-->=<!--> <!-->0.63). However, the indirect effect of IPV severity on disability mediated by depressive symptoms was (β<!--> <!-->=<!--> <!-->0.39; <em>P</em> <!--><<!--> <!-->0.01). The total effect of IPV severity on the level of disability was even greater (β<!--> <!-->=<!--> <!-->0.48; <em>P</em> <!-->=<!--> <!-->0.01).</p></div><div><h3>Conclusions</h3><p>This study found a complete mediating role of depressive symptoms on the relationship between the severity of IPV and the level of disability for the female participants in this study. The results of this research contribute to defining strategies to prevent and address intimate partner violence, depressive symptoms and disability in this population.</p></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 55-62"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140030511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2021.11.010
Mely Olarte-Durand , Jossiel B. Roque-Aycachi , Ricardo Rojas-Humpire , Josue F. Canaza-Apaza , Stefani Laureano , Andrea Rojas-Humpire , Salomón Huancahuire-Vega
Introduction
The prolongation and consequences of the COVID-19 pandemic have led to an uncertain and devastating panorama in many populations, and the evidence shows a high prevalence of mental health problems in medical students. The objective was to evaluate the association between mood disorders and sleep quality (SQ) in Peruvian medical students during the COVID-19 pandemic.
Methods
A cross-sectional study was conducted on 310 medical students from a private university in Peru. The SQ was measured using the Pittsburgh Sleep Quality Index (PSQI), while mood disorders were evaluated using the Depression Anxiety and Stress Scale-21 (DASS-21). All information was collected by online surveys and then analysed in the R programming language.
Results
The SQ results measured by PSQI were poor in 83.9% of the medical students. In the Poison regression analysis, the results of the bivariate analysis in men show that all mood disorders found the prevalence of poor SQ. However, in the multivariate analysis only stress (PRa = 1.30; 95% CI, 1.08-1.57; P < 0.01) and anxiety (PRa = 1.34; 95% CI, 1.09-1.56; P < 0.01) increased the prevalence of poor SQ. Women had a similar pattern in bivariate analysis, whereas in multivariate analysis, only severe stress (PRa = 1.15; 95% CI, 1.01-1.29; P < 0.05) increased the prevalence of poor SQ.
Conclusions
This study allows us to observe the consequences that the COVID-19 pandemic is having on medical students in Peru. It also revealed a population group vulnerable to poor quality of sleep and bad mood, which in the future will impact on health. It is suggested to educate medical students about the importance of proper sleep hygiene and the consequences of poor sleep hygiene practices.
{"title":"Mood and Sleep Quality in Peruvian Medical Students During COVID-19 Pandemic","authors":"Mely Olarte-Durand , Jossiel B. Roque-Aycachi , Ricardo Rojas-Humpire , Josue F. Canaza-Apaza , Stefani Laureano , Andrea Rojas-Humpire , Salomón Huancahuire-Vega","doi":"10.1016/j.rcp.2021.11.010","DOIUrl":"10.1016/j.rcp.2021.11.010","url":null,"abstract":"<div><h3>Introduction</h3><p>The prolongation and consequences of the COVID-19 pandemic have led to an uncertain and devastating panorama in many populations, and the evidence shows a high prevalence of mental health problems in medical students. The objective was to evaluate the association between mood disorders and sleep quality (SQ) in Peruvian medical students during the COVID-19 pandemic.</p></div><div><h3>Methods</h3><p>A cross-sectional study was conducted on 310 medical students from a private university in Peru. The SQ was measured using the Pittsburgh Sleep Quality Index (PSQI), while mood disorders were evaluated using the Depression Anxiety and Stress Scale-21 (DASS-21). All information was collected by online surveys and then analysed in the R programming language.</p></div><div><h3>Results</h3><p>The SQ results measured by PSQI were poor in 83.9% of the medical students. In the Poison regression analysis, the results of the bivariate analysis in men show that all mood disorders found the prevalence of poor SQ. However, in the multivariate analysis only stress (PRa<!--> <!-->=<!--> <!-->1.30; 95% CI, 1.08-1.57; <em>P</em> <!--><<!--> <!-->0.01) and anxiety (PRa<!--> <!-->=<!--> <!-->1.34; 95% CI, 1.09-1.56; <em>P</em> <<!--> <!-->0.01) increased the prevalence of poor SQ. Women had a similar pattern in bivariate analysis, whereas in multivariate analysis, only severe stress (PRa<!--> <!-->=<!--> <!-->1.15; 95% CI, 1.01-1.29; <em>P</em> <<!--> <!-->0.05) increased the prevalence of poor SQ.</p></div><div><h3>Conclusions</h3><p>This study allows us to observe the consequences that the COVID-19 pandemic is having on medical students in Peru. It also revealed a population group vulnerable to poor quality of sleep and bad mood, which in the future will impact on health. It is suggested to educate medical students about the importance of proper sleep hygiene and the consequences of poor sleep hygiene practices.</p></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 47-54"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39835139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2021.11.004
Jhonny Alejandro Muñoz Valencia , Jose Ricardo Muñoz Zuñiga , Juan Carlos Rivas Nieto
Introduction
Post-traumatic stress disorder (PTSD) is characterised by intrusive, anxious, and avoidant symptoms that are triggered after a stressful experience and affect the mood. The definition of a stressor that generates PTSD has been debated in recent years, as a clinical picture compatible with the disorder can occur after exposure to stressors that do not meet the criteria A1 of the DSM V; these stressors have been defined in the literature as “of low magnitude, uncommon, unusual or atypical”.
Clinical case
We present the clinical case of a paediatric patient who developed PTSD after being exposed to an atypical stressor.
Conclusions
The literature shows these stressors to be more frequently documented in the paediatric population. We therefore suggest that cases should be analysed as a complex interweaving of variables, where one of the most important is each patient's interpretation of the event according to their life history and social context, and not because of an inherent characteristic of the stressor itself.
导言:创伤后应激障碍(PTSD)的特点是在应激经历后引发侵入性、焦虑和回避症状,并影响情绪。近年来,关于产生创伤后应激障碍的应激源的定义一直存在争议,因为在暴露于不符合 DSM V 标准 A1 的应激源后,也可能出现与创伤后应激障碍相符的临床表现;这些应激源在文献中被定义为 "低强度、不常见、不寻常或非典型"。因此,我们建议将病例作为一个复杂的交织变量来分析,其中最重要的一个变量是每个患者根据其生活史和社会背景对事件的解释,而不是因为应激源本身的固有特征。
{"title":"Paciente adolescente con trastorno de estrés postraumático debido a estresor atípico. Reporte de caso","authors":"Jhonny Alejandro Muñoz Valencia , Jose Ricardo Muñoz Zuñiga , Juan Carlos Rivas Nieto","doi":"10.1016/j.rcp.2021.11.004","DOIUrl":"10.1016/j.rcp.2021.11.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Post-traumatic stress disorder (PTSD) is characterised by intrusive, anxious, and avoidant symptoms that are triggered after a stressful experience and affect the mood. The definition of a stressor that generates PTSD has been debated in recent years, as a clinical picture compatible with the disorder can occur after exposure to stressors that do not meet the criteria A1 of the DSM V; these stressors have been defined in the literature as “of low magnitude, uncommon, unusual or atypical”.</p></div><div><h3>Clinical case</h3><p>We present the clinical case of a paediatric patient who developed PTSD after being exposed to an atypical stressor.</p></div><div><h3>Conclusions</h3><p>The literature shows these stressors to be more frequently documented in the paediatric population. We therefore suggest that cases should be analysed as a complex interweaving of variables, where one of the most important is each patient's interpretation of the event according to their life history and social context, and not because of an inherent characteristic of the stressor itself.</p></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 103-106"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47658024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2022.01.005
Luz Angela Rojas Bernal , Hernando Santamaría García , Guillermo Alonso Castaño Pérez
Introduction
The co-occurrence of substance use disorder with at least one other mental disorder is called dual pathology, which in turn is characterised by heterogeneous symptoms that are difficult to diagnose and have a poor response to treatment. For this reason, the identification and validation of biomarkers is necessary. Within this group, possible electroencephalographic biomarkers have been reported to be useful in diagnosis, treatment and follow-up, both in neuropsychiatric conditions and in substance use disorders. This article aims to review the existing literature on electroencephalographic biomarkers in dual pathology.
Methods
A narrative review of the literature. A bibliographic search was performed on the PubMed, Science Direct, OVID, BIREME and Scielo databases, with the key**words: electrophysiological biomarker and substance use disorder, electrophysiological biomarker and mental disorders, biomarker and dual pathology, biomarker and substance use disorder, electroencephalography, and substance use disorder or comorbid mental disorder.
Results
Given the greater amount of literature found in relation to electroencephalography as a biomarker of mental illness and substance use disorders, and the few articles found on dual pathology, the evidence is organised as a biomarker in psychiatry for the diagnosis and prediction of risk and as a biomarker for dual pathology.
Conclusions
Although the evidence is not conclusive, it suggests the existence of a subset of sites and mechanisms where the effects of psychoactive substances and the neurobiology of some mental disorders could overlap or interact.
{"title":"Biomarcadores electrofisiológicos en patología dual","authors":"Luz Angela Rojas Bernal , Hernando Santamaría García , Guillermo Alonso Castaño Pérez","doi":"10.1016/j.rcp.2022.01.005","DOIUrl":"10.1016/j.rcp.2022.01.005","url":null,"abstract":"<div><h3>Introduction</h3><p>The co-occurrence of substance use disorder with at least one other mental disorder is called dual pathology, which in turn is characterised by heterogeneous symptoms that are difficult to diagnose and have a poor response to treatment. For this reason, the identification and validation of biomarkers is necessary. Within this group, possible electroencephalographic biomarkers have been reported to be useful in diagnosis, treatment and follow-up, both in neuropsychiatric conditions and in substance use disorders. This article aims to review the existing literature on electroencephalographic biomarkers in dual pathology.</p></div><div><h3>Methods</h3><p>A narrative review of the literature. A bibliographic search was performed on the PubMed, Science Direct, OVID, BIREME and Scielo databases, with the key**words: electrophysiological biomarker and substance use disorder, electrophysiological biomarker and mental disorders, biomarker and dual pathology, biomarker and substance use disorder, electroencephalography, and substance use disorder or comorbid mental disorder.</p></div><div><h3>Results</h3><p>Given the greater amount of literature found in relation to electroencephalography as a biomarker of mental illness and substance use disorders, and the few articles found on dual pathology, the evidence is organised as a biomarker in psychiatry for the diagnosis and prediction of risk and as a biomarker for dual pathology.</p></div><div><h3>Conclusions</h3><p>Although the evidence is not conclusive, it suggests the existence of a subset of sites and mechanisms where the effects of psychoactive substances and the neurobiology of some mental disorders could overlap or interact.</p></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 93-102"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47994083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2021.10.009
Elard Bottoni-Tito, Wendy Messa-Aguilar
Objectives
To describe haematological adverse effects in adolescents with anorexia nervosa who are taking olanzapine.
Methods
Case series report.
Case report
The reported cases (two female patients and one male) were found to have blood test abnormalities after starting olanzapine and to rapidly recover their platelet and neutrophil values after the drug was discontinued. Low haemoglobin values persisted longer than observed in other series. These abnormalities became more noticeable when the dose of olanzapine was increased to 5 mg/day (initial dose 2.5 mg/day). It should be noted that two of the patients already had values indicative of mild neutropenia before they started the antipsychotic drug, and that these worsened as they continued taking the drug. In one of the patients there was only a decrease in neutrophil values, as well as mild anaemia.
Conclusions
This first case series of haematological abnormalities in adolescents with anorexia nervosa who are taking olanzapine found values corresponding to pancytopenia in two of the three cases reported. It would be worthwhile to consider heightening haematological surveillance in this population when starting treatment with olanzapine and rethinking our knowledge regarding the frequency of these side effects.
{"title":"Efectos Adversos Hematológicos Asociados con Olanzapina en Adolescentes con Anorexia Nerviosa: Reporte de 3 Casos","authors":"Elard Bottoni-Tito, Wendy Messa-Aguilar","doi":"10.1016/j.rcp.2021.10.009","DOIUrl":"10.1016/j.rcp.2021.10.009","url":null,"abstract":"<div><h3>Objectives</h3><p>To describe haematological adverse effects in adolescents with anorexia nervosa who are taking olanzapine.</p></div><div><h3>Methods</h3><p>Case series report.</p></div><div><h3>Case report</h3><p>The reported cases (two female patients and one male) were found to have blood test abnormalities after starting olanzapine and to rapidly recover their platelet and neutrophil values after the drug was discontinued. Low haemoglobin values persisted longer than observed in other series. These abnormalities became more noticeable when the dose of olanzapine was increased to 5 mg/day (initial dose 2.5<!--> <!-->mg/day). It should be noted that two of the patients already had values indicative of mild neutropenia before they started the antipsychotic drug, and that these worsened as they continued taking the drug. In one of the patients there was only a decrease in neutrophil values, as well as mild anaemia.</p></div><div><h3>Conclusions</h3><p>This first case series of haematological abnormalities in adolescents with anorexia nervosa who are taking olanzapine found values corresponding to pancytopenia in two of the three cases reported. It would be worthwhile to consider heightening haematological surveillance in this population when starting treatment with olanzapine and rethinking our knowledge regarding the frequency of these side effects.</p></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 107-111"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44259409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.rcp.2022.01.003
André Pereira Gonçalves , Gabriel Carvalho Franco , Guilherme Miquelino Francisco
Objective
The aim of the present study was to verify the psychometric qualities of the PID-5-FBF in a community sample of Brazilian adults. The internal consistency of the facets and the internal structure of the dimensions were checked. In addition, we verified the correlations between the PID-5-FBF facets and domains with a five-factor model measure.
Methods
The sample of this study consists of the 774 Brazilian adults aged 18 to 73 years (mean 28.9 ± 11.58) who answered the PID-5-FBF and BFI-2S.
Results
The alpha values were adequate. The internal structure was similar to the PID-5 original form. All the factors and dimensions of the PID-5-FBF have a negative association with agreeableness, while, on the other hand, all correlations with neuroticism were positive. Neuroticism was the factor with the highest correlation with the PID-5-FBF, and openness was the one with the lowest number of correlations.
Conclusions
This research contributes to adding evidence of validity to the PID-5-FBF in the Brazilian community sample. Our results are important because it is the first study with the PID-FBF in a Brazilian sample.
{"title":"Psychometric Properties of the Personality Inventory for DSM-5 faceted Brief Form in a Brazilian Community Sample","authors":"André Pereira Gonçalves , Gabriel Carvalho Franco , Guilherme Miquelino Francisco","doi":"10.1016/j.rcp.2022.01.003","DOIUrl":"10.1016/j.rcp.2022.01.003","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of the present study was to verify the psychometric qualities of the PID-5-FBF in a community sample of Brazilian adults. The internal consistency of the facets and the internal structure of the dimensions were checked. In addition, we verified the correlations between the PID-5-FBF facets and domains with a five-factor model measure.</p></div><div><h3>Methods</h3><p>The sample of this study consists of the 774 Brazilian adults aged 18 to 73 years (mean 28.9<!--> <!-->±<!--> <!-->11.58) who answered the PID-5-FBF and BFI-2S.</p></div><div><h3>Results</h3><p>The alpha values were adequate. The internal structure was similar to the PID-5 original form. All the factors and dimensions of the PID-5-FBF have a negative association with agreeableness, while, on the other hand, all correlations with neuroticism were positive. Neuroticism was the factor with the highest correlation with the PID-5-FBF, and openness was the one with the lowest number of correlations.</p></div><div><h3>Conclusions</h3><p>This research contributes to adding evidence of validity to the PID-5-FBF in the Brazilian community sample. Our results are important because it is the first study with the PID-FBF in a Brazilian sample.</p></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 1","pages":"Pages 26-31"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45078329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}