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Soursop Leaf Nanoparticles On Blood Glucose Levels And Ankle Brachial Pressure Index (ABPI) Values In Type-2 Diabetes Mellitus Patients 酸果树叶纳米颗粒对 2 型糖尿病患者血糖水平和踝肱压指数 (ABPI) 值的影响
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.9826
Taadi Samsuri, M. Mardiyono, U. Rahayu, Iken Anggraini Sri Saputri
Chronic hyperglycemia will cause legs and blood circulation disorders. Treatment with insulin is still quite expensive and with some side effects of oral hypoglycemic drugs. This experience made the management of DM switch to herbal treatment, namely soursop leaves (Annona muricata). The study used a pre and post test control group design with random allocation. Quasy experimental study with a two group pre tpost-testest – post tepost-testst design at 36type-2 DM patients in the Pekalongan City area. Blood glucose levels in the treatment group were measured before and after administration of soursop leaf nanoparticles500 ml/20 gBB 3 times a day for 6 days and 500 mg metformin. Giving soursop leaf nanoparticles at a dose of 500 ml/20 grBW 3 times a day for 6 days is effective on fasting blood glucose levels clinically with a change in value of 65 mg/dL, and has a statistically significant effect on reducing fasting glucose levels (p=0.035).
长期高血糖会导致腿部和血液循环障碍。使用胰岛素治疗仍然相当昂贵,而且口服降糖药有一定的副作用。因此,DM 的治疗转为中药治疗,即酸枣仁叶(Annona muricata)。该研究采用随机分配的前后对照组设计。在北加龙根市地区的 36 名 2 型糖尿病患者中进行了两组前 t 后试验--后 t 后试验设计的asy 实验研究。在服用酸浆树叶纳米颗粒 500 毫升/20 gBB,每天 3 次,连续 6 天和 500 毫克二甲双胍前后,测量治疗组的血糖水平。以每天 3 次,每次 500 毫升/20 克体重的剂量服用酸果树叶纳米颗粒,连续服用 6 天,对空腹血糖水平有临床疗效,血糖值的变化幅度为 65 毫克/分升,并且对降低空腹血糖水平有显著的统计学效果(P=0.035)。
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引用次数: 0
Effectiveness Of Dynamic Neuromuscular Stabilization Exercise On Reducing Pain In The Elderly With Genu Osteoarthritis 动态神经肌肉稳定运动对减轻骨关节炎老人疼痛的效果
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.9927
Shahad Erma Nurhayati, Cahyo Setiawan, Dea Linia Romadhoni, Asita Rohmah Mutnawasitoh
A pattern of muscle imbalance is seen clinically in osteoarthritis. Quadriceps weakness has been identified as a cause of osteoarthritis in the genu, indicating a link between muscle imbalance and osteoarthritis. The DNS approach aims to exploit brain plasticity and reactivate the patient's dormant natural motor patterns, stimulating global motor reactions and minimizing muscle imbalance. The purpose of this study was to determine the effectiveness of giving dynamic neuromuscular stabilization exercise on pain reduction in the elderly with genu osteoarthritis. This type of research is quantitative: a quasi-experimental pre-post test with a control group design non random sampling with a sample of 50 subjects divided into two groups, namely 25 experimental groups and 25 control groups. The research instruments used closed questionnaires, structured interviews, and pain measurements with NRS. Dynamic Neuromuscular Stabilization Exercise intervention was carried out twice a week for 4 weeks. Data processing in this study used SPSS software program version 26. Data analysis was carried out in the form of a data normality test using the Kolmogorov Smirnov test because the number of subjects was 50 ( ≥ 50) people, and the differential effect test used was the Mann-Whitney Test because the data was not normally distributed. The results of this study indicate that there is a difference in influence between the experimental group and the control group of NRS values of p=0.044. There is an effect on the experimental group, and there is a difference in the effect on the experimental group compared to the control group. For future research, it is hoped that if you want to use the same DNS exercise, choose a different dose from this study so that you can see the difference in results and have a newer reference from a different dose.
骨关节炎的临床表现为肌肉失衡。已确定股四头肌无力是造成膝关节骨关节炎的原因之一,这表明肌肉失衡与骨关节炎之间存在联系。DNS 方法旨在利用大脑的可塑性,重新激活患者休眠的自然运动模式,刺激整体运动反应,最大限度地减少肌肉失衡。本研究的目的是确定对患有真性骨关节炎的老年人进行动态神经肌肉稳定训练对减轻疼痛的效果。该研究类型为定量研究:采用对照组设计的非随机抽样的准实验前-后测试,样本为 50 名受试者,分为两组,即 25 名实验组和 25 名对照组。研究工具采用封闭式问卷、结构式访谈和 NRS 疼痛测量法。动态神经肌肉稳定运动干预每周进行两次,为期 4 周。本研究使用 SPSS 软件 26 版本进行数据处理。由于受试者人数为 50(≥ 50)人,数据分析采用 Kolmogorov Smirnov 检验法进行数据正态性检验;由于数据不呈正态分布,采用 Mann-Whitney 检验法进行差异效应检验。研究结果表明,实验组与对照组 NRS 值的影响存在差异,P=0.044。实验组存在影响,而且实验组与对照组相比,影响存在差异。对于今后的研究,希望大家如果想使用同样的 DNS 锻炼,可以选择本研究中不同的剂量,这样可以看到结果的差异,也可以从不同的剂量中获得更新的参考。
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引用次数: 0
Ffect Peppermint Aromatherapy Inhalation Reducing Nausea And Vomiting In First Trimester Of Pregnancy 吸入薄荷芳香疗法可减轻妊娠头三个月的恶心和呕吐症状
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.9913
Putu Elsa Yuliani, Ni Nyoman Suindri, I. N. Wirata
The Nausea and vomiting in pregnant women in the first trimester was physiologically due to an increase in the Human Chorionic Gonadotrophin (HCG) hormone which affects the digestive system, causing complaints of nausea and vomiting. One of them was handling nausea and vomiting by administering peppermint aromatherapy inhalation. Peppermint had a sharp menthol aroma, a distinctive cold refreshing smell, and the smell of menthol which had properties against contractions by inhibiting muscle contact caused by serotonin hormone so that it could successfully overcome nausea and vomiting in pregnant women. This study aims to determine the differences in nausea and vomiting before and after administration of peppermint aromatherapy inhalation dose, 0,1-0,2 ml for 1-10 minutes to pregnant women in their first This type of research was quasi-experimental, one-group pre-and post-test design. The number of samples was 48 respondents intervention and treatments, with the sampling method "purposive sampling" type of non-probability sampling. The data collection tool was a Pregnancy Unique Quantification of Emesis and Nausea (PUQE) questionnaire. Data analysis techniques used univariate and bivariate analysis. The results of data analysis used the Wilcoxon test and obtained a p-value of 0. 000 p 0. 05. This means that there were differences in nausea and vomiting before and after giving peppermint aromatherapy inhalation to pregnant women in their first trimester. It is expected that pregnant women use peppermint aromatherapy inhalation to treat nausea and vomiting because it does not have a toxic effect on the health of the mother and fetus.
孕妇在怀孕头三个月出现恶心和呕吐的生理原因是人绒毛膜促性腺激素(HCG)激素增加,这种激素会影响消化系统,引起恶心和呕吐。其中一种处理恶心和呕吐的方法是吸入薄荷芳香疗法。薄荷具有尖锐的薄荷香气、独特的冰凉清爽的气味以及薄荷醇的气味,这些气味通过抑制血清素激素引起的肌肉接触而具有抗收缩的特性,因此可以成功克服孕妇的恶心和呕吐。本研究旨在确定初产孕妇在吸入薄荷芳香疗法(0.1-0.2 毫升,持续 1-10 分钟)前后恶心和呕吐的差异。 本研究采用准实验、单组前后测试设计。样本数量为 48 个干预和治疗受访者,抽样方法为 "目的性抽样 "的非概率抽样类型。数据收集工具为妊娠期呕吐和恶心独特定量(PUQE)问卷。数据分析技术采用单变量和双变量分析。数据分析结果采用 Wilcoxon 检验,P 值为 0.这说明在给怀孕头三个月的孕妇吸入薄荷芳香疗法前后,恶心和呕吐的情况存在差异。由于薄荷香薰吸入剂不会对母亲和胎儿的健康产生毒副作用,因此孕妇有望使用薄荷香薰吸入剂来治疗恶心和呕吐。
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引用次数: 0
Factors Associated With Administration of Antiplatelet Therapy on The NIHSS Score in Acute Ischemic Stroke 急性缺血性脑卒中患者服用抗血小板疗法影响 NIHSS 评分的相关因素
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.9731
Eddy Ratnaningsih Chrisstawati, M.I. Ekatrina Wijayanti, Tandean Arif Wibowo
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引用次数: 0
Analysis of P4K Filling in The MCH Book with Factor of Maternal Death Based on Three Delays (3T) in 2022 In The Jember District 根据 2022 年的三次延迟 (3T) 分析妇幼保健手册中的 P4K 填报情况
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.9764
Salsha Billah Putri Radicha, Devi Arine Kusumawardani, Sofiyanti Miftakhurohmah
The Birth Preparedness and Complication Readiness Program (P4K) is an effort to overcome maternal mortality by reducing three delays (3T), late decision-making, late reaching health facilities, and late getting treatment. The purpose of this study was to analyze P4K filling in maternal and child health (MCH) books with the causes of maternal death based on three delays (3T). The method used in this study is quantitative and descriptive using data on 58 cases of maternal death found at the Jember District Health Office. The results of this study were that there were 15 (25.8%) cases of maternal death with P4K in the MCH handbook which were incompletely filled in and identified as experiencing three delays and 12 (20.6%) cases of maternal death with P4K in the MCH handbook which were not filled out. This research can be used as material for evaluating the Birth Preparedness and Complication Readiness Program (P4K).
分娩准备和并发症准备计划(P4K)旨在通过减少三个延迟(3T),即决策延迟、到达医疗机构延迟和接受治疗延迟,来降低孕产妇死亡率。本研究的目的是分析 P4K 在妇幼保健(MCH)书籍中的填写情况,以及基于三个延迟(3T)的孕产妇死亡原因。本研究采用定量和描述性的方法,使用了在 Jember 区卫生局发现的 58 例产妇死亡病例的数据。研究结果表明,有 15 例(25.8%)孕产妇死亡病例的母婴保健手册中的 P4K 未完整填写并被确定为经历了三次延误,有 12 例(20.6%)孕产妇死亡病例的母婴保健手册中的 P4K 未完整填写。这项研究可作为评估分娩准备和并发症准备计划(P4K)的材料。
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引用次数: 0
Assessing Efficiency and Image Quality of Dental Radiography Using Modified Dental Holders with Silicone Rubber Integration 评估使用硅橡胶集成改良牙托进行牙科射线照相的效率和图像质量
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.10484
M. Jannah, Sri Mulyati, Wingghayarie Patra Gandhi
This study aims to evaluate the efficiency of use by radiographers and image quality in the use of dental holders that have been modified with silicone rubber in dental radiography procedures. Motivated by the problem in the use of conventional dental holders that often cause discomfort for patients and the potential for motion artifacts, a modification with silicone rubber was proposed. The study sample involved 16 repetitions on each head cadaver using both the innovative and control dental holders. The results of the paired t-test showed a significant difference in efficiency of use by radiographers and image quality between the two groups. The efficiency of use by radiographers increased, supported by a Cohen's d value of 9.632. The modification with silicone rubber showed better images, with a Cohen's d value of 0.325, attributed to the adjustable conus guide capability according to the size of the patient's mouth and jaw as well as the increased comfort with the silicone rubber material. This study recommends the adoption of the modified dental holder to improve procedure efficiency and quality of dental radiography results.
本研究旨在评估在牙科放射摄影程序中使用经硅橡胶改良的牙科支架时放射技师的使用效率和图像质量。传统的牙科支架在使用过程中经常会给患者带来不适,并有可能产生运动伪影,有鉴于此,研究人员提出了使用硅橡胶改良的牙科支架。研究样本包括使用创新型牙夹和对照牙夹在每个头部尸体上重复 16 次。配对 t 检验结果显示,两组放射技师的使用效率和图像质量存在显著差异。放射技师的使用效率提高了,科恩氏 d 值为 9.632。使用硅橡胶的改良版显示出更好的图像,Cohen's d 值为 0.325,这归功于可根据患者口腔和下颌的大小进行调节的锥体引导能力,以及硅橡胶材料带来的更高舒适度。本研究建议采用改良型牙科支架,以提高手术效率和牙科射线成像结果的质量。
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引用次数: 0
Quality Of Life For Adolescents With Divorced Parents On Physical And Psychological Conditions In Indonesia: Literature Review 印度尼西亚父母离异青少年在生理和心理状况方面的生活质量:文献综述
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.9958
Vierthycia Izzatul Haq, Dimas B. C. Wicaksono
Quality of life can be interpreted as a person's view of life related to culture, values, and other factors. The quality of life of adolescents in Indonesia can be influenced by various factors, such as family. Families with divorced parents must experience differences and changes from families with intact parents. The purpose of this study was to describe the quality of life of adolescents in terms of physical and psychological conditions with divorced parents in Indonesia. The research method used in this research is Literature Review. The search for journal articles used 4 databases with a combination of the PICO(S) components and met the inclusion criteria so that 31 articles were extracted according to the research objectives. The results of the analysis show that the quality of life of adolescents with divorced parents depends on each of these adolescents. Physical condition can be seen from the components of pain and discomfort, energy and fatigue, and sleep and rest. And psychological conditions can be seen from the components of positive feeling, thinking, learning, memory, and concentration, negative feelings, self-esteem, and spirituality personal belief.
生活质量可以解释为一个人对与文化、价值观和其他因素有关的生活的看法。印度尼西亚青少年的生活质量可能受到家庭等各种因素的影响。父母离异的家庭一定会经历与父母完整家庭的差异和变化。本研究的目的是描述印尼父母离异的青少年在生理和心理状况方面的生活质量。本研究采用的研究方法是文献综述。期刊论文的搜索使用了 4 个数据库,并结合了 PICO(S) 要素,符合纳入标准,因此根据研究目标提取了 31 篇文章。分析结果表明,父母离异青少年的生活质量取决于这些青少年中的每一个人。身体状况可以从疼痛与不适、精力与疲劳、睡眠与休息这几个部分看出。心理状况可以从积极情绪、思维、学习、记忆和注意力、消极情绪、自尊和个人精神信仰等方面看出。
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引用次数: 0
The Correlation Of Preeclampsia, Age, And Type Of Delivery In Postpartum Hemorrhage 产后出血中先兆子痫、年龄和分娩方式的相关性
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.10023
Rafi Andyah Arum Kedaton, Mimi Ruspita, Hanifa Andisetyana Putri
The number of maternal deaths in Semarang City in 2021 was 21 cases out of 22,030 live births, or around 95.32 deaths per 100,000 live births, with the causes of death dominated by bleeding (14.29%) and hypertension (9.52%). Postpartum hemorrhage is caused by four main factors known as the 4T: tone, trauma, tissue, and thrombin. This study was conducted to determine the relationship between preeclampsia, maternal age, and type of delivery with the incidence of postpartum hemorrhage at Central General Hospital Dr. Kariadi Semarang in 2020–2022. The study was an analytic observational quantitative research with a retrospective case control study. The study was conducted in February 2023 with a total sample of 100 samples divided into case (total sampling) and control (simple random sampling) groups with a ratio of 1: 1 for each group. Statistical tests used Chi-square and odds ratio (OR) tests. The results showed that there was no relationship between preeclampsia and the incidence of postpartum hemorrhage (p-value = 0.063; OR = 0.347), there was a relationship between maternal age and the incidence of postpartum hemorrhage (p-value = 0.011; OR = 3.455), and there was a relationship between the type of delivery and postpartum hemorrhage (p-value = 0.012; OR = 2.923). The community can be expected to play an active role in integrated service post cadre activities and ante natal care assistance. Health workers and educational institutions also need to improve their knowledge and skills to form qualified health workers through certified training.
2021 年,三宝垄市的产妇死亡人数为 22 030 例活产中的 21 例,即每 10 万活产中约有 95.32 例死亡,死亡原因主要是出血(14.29%)和高血压(9.52%)。产后出血是由被称为 4T 的四个主要因素引起的:张力、创伤、组织和凝血酶。本研究旨在确定2020-2022年先兆子痫、产妇年龄和分娩类型与三宝垄卡瑞迪博士中央综合医院产后出血发生率之间的关系。该研究是一项回顾性病例对照分析观察定量研究。研究于 2023 年 2 月进行,样本总数为 100 个,分为病例组(总体抽样)和对照组(简单随机抽样),每组比例为 1:1。统计检验采用了卡方检验(Chi-square)和几率比验(OR)。结果显示,先兆子痫与产后出血发生率之间没有关系(P 值 = 0.063;OR = 0.347),产妇年龄与产后出血发生率之间有关系(P 值 = 0.011;OR = 3.455),分娩方式与产后出血之间有关系(P 值 = 0.012;OR = 2.923)。社区可望在综合服务岗位干部活动和产前护理援助中发挥积极作用。卫生工作者和教育机构也需要提高知识和技能,通过认证培训培养合格的卫生工作者。
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引用次数: 0
Risk Factors for Dental Caries in Elementary School Children Aged 6-12 in Indonesia (Systematic Literatur Review) 印度尼西亚 6-12 岁小学生龋齿的风险因素(系统文献综述)
Pub Date : 2023-11-30 DOI: 10.31983/jrk.v12i2.9988
Vilianti Eka Fitri Rahatina, S. Hadisaputro, Henry Setyawan S
Background: The highest prevalence of dental caries was in the group of children aged 5-9 years (92.6%), and in the age group 3-4 years was 81.1%. Unhealthy teeth and mouth can affect a child's development because the condition of the milk teeth will determine the growth of the child's permanent teeth. Caries are influenced by brushing teeth, how to brush teeth, consumption of cariogenic foods, knowledge, and possibly many other factors that can affect caries. Purpose: to review the collected literature on risk factors for dental caries in children aged 6-12 years in Indonesia. Methods: This study used the literature review method which began with searching research results in 3 databases, namely PubMed, ScienceDirect, and Google Scholar with predetermined inclusion criteria. Results: The articles that have been obtained in this literature show that there are many variables in the process of dental caries in elementary school children in Indonesia. These variables are divided into several discussion groups, namely individual characteristics, parental characteristics, consumption patterns, dental and oral hygiene, socioeconomic status, and dental and oral health interventions. Conclusion: there are many variables selected to be risk factors for dental caries, but not all variables are proven to be risk factors for dental caries in elementary school children. This is because other factors make the hypothesis rejected.
背景:龋齿发病率最高的年龄组是 5-9 岁儿童(92.6%),3-4 岁年龄组为 81.1%。不健康的牙齿和口腔会影响儿童的发育,因为乳牙的状况将决定儿童恒牙的生长。影响龋齿的因素包括刷牙、刷牙方法、食用致龋食物、知识以及可能影响龋齿的许多其他因素。目的:回顾收集到的有关印度尼西亚 6-12 岁儿童龋齿风险因素的文献。研究方法本研究采用文献综述法,首先在 3 个数据库(即 PubMed、ScienceDirect 和 Google Scholar)中搜索研究成果,并预先确定纳入标准。研究结果从这些文献中获得的文章表明,印尼小学生龋齿过程中存在许多变量。这些变量分为几个讨论组,即个人特征、父母特征、消费模式、牙齿和口腔卫生、社会经济状况以及牙齿和口腔健康干预措施。结论:有许多变量被选为龋齿的风险因素,但并非所有变量都被证明是小学生龋齿的风险因素。这是因为其他因素使得假设被否定。
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引用次数: 0
THE EFFECTIVENESS OF ETHANOL EXTRACT OF JAMBLANG LEAVES (Syzygium cumini L.) IN INCREASING HDL LEVELS IN WISTAR RATS MODELS OF METABOLIC SYNDROME JAMBLANG叶乙醇提取物的药效研究提高代谢综合征wistar大鼠模型中HDL水平的作用
Pub Date : 2023-06-02 DOI: 10.31983/jrk.v12i1.9305
M. Muthmainah, Ida Nurwati, S. Handayani, Dyonisa Nasirochmi Pakha
One of the characteristics of metabolic syndrome (MetS) is the low high-density lipoprotein (HDL) levels. Jamblang leaves (Syzygium cumini L.) contain various phytochemicals, which have antihyperglycemic, antihyperlipidemic, and antioxidant properties. This study aims to demonstrate the effectiveness of ethanol extract of jamblang leaves in increasing HDL levels in the Wistar rats model of MetS. A pretest-posttest with a control group design was conducted using 30 male Wistar rats, divided into five groups randomly, with six rats for each group.  Here, KN means normal control group, K- negative control group, and P1, P2, and P3: treatment groups that were administered the 100 mg/kg/day, 150 mg/kg/day, and 200 mg/kg/day of ethanol extract of jamblang leaves for 28 days, respectively. The rat MetS model was developed by administering the high-fat fructose diet and streptozotocin-nicotinamide. The data were analyzed using paired t-test and one-way ANOVA (α=0.05). This study found that extract administration in P2 and P3 increased HDL levels significantly, but not with the P1 group. However, HDL levels in P1 were significantly higher compared to the K- group. Moreover, increasing the dose was significantly followed by higher HDL levels, although the highest dose did not reach the HDL level as in the KN group.
代谢综合征(MetS)的特征之一是高密度脂蛋白(HDL)水平低。孜然叶(Syzygium cumini L.)含有多种植物化学物质,具有抗高血糖、抗高血脂和抗氧化特性。本研究旨在证明侧柏叶乙醇提取物在MetS Wistar大鼠模型中提高HDL水平的有效性。使用30只雄性Wistar大鼠进行对照组设计的前测后测,随机分为5组,每组6只。这里,KN是指正常对照组、K-阴性对照组以及P1、P2和P3:分别给药100mg/kg/天、150mg/kg/天和200mg/kg/天的侧柏叶乙醇提取物28天的治疗组。通过给予高脂肪果糖饮食和链脲佐菌素烟酰胺建立大鼠代谢综合征模型。使用配对t检验和单因素方差分析(α=0.05)对数据进行分析。本研究发现,P2和P3组的提取物给药显著提高了HDL水平,但P1组没有。然而,P1组的HDL水平明显高于K组。此外,增加剂量后HDL水平显著升高,尽管最高剂量没有达到KN组的HDL水平。
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引用次数: 0
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Jurnal Riset Kesehatan
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