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A qualitative study of mealtime difficulties in patients with dementia who feed themselves 痴呆症患者进食困难的定性研究
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8242
D. Damayanthi, A. M. N. L. D. Silva, I. Gunathilake, C. Suraweera
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引用次数: 0
Sexual desire, sexual functioning and well-being in married males: a community based study 已婚男性的性欲、性功能和幸福感:一项基于社区的研究
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8221
G. Lakshmana, F. Mohd, A. Panda
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引用次数: 0
Non-invasive brain stimulation – a new way forward for psychiatric disorders? 非侵入性脑刺激——治疗精神疾病的新方法?
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8245
A. Hapangama, S. Perera
Repetitive transcranial magnetic stimulation (rTMS) is the focal application of a localized, pulsed magnetic field to the cerebral cortex, resulting in the induction of a small electrical currents that stimulate nerve cells in the region of the brain involved in mood regulation and depression. Similar to electroconvulsive therapy (ECT), it is noninvasive, however unlike ECT it does not involve use of an anaesthetic, seizure induction or loss of consciousness. The Professional Practice Guidelines (PPG 16) of the Royal Australian and New Zealand College of Psychiatrists as well as the Interventional procedures guidance [IPG542] of the National Institute of Clinical Excellence (NICE) of the United Kingdom both list depression as the primary clinical indication for rTMS. The PPG 16 also states that there is accumulating evidence for use of rTMS in obsessive compulsive disorder, but given the wide variety of treatment targets and paradigms used in different studies, it is still difficult to make an overall conclusion. The guideline highlights that the evidence for use of rTMS in schizophrenia is less substantive, with lack of multi-centre trials, but may be considered for patients with persistent auditory hallucinations despite optimal medication, to be delivered with specialist training.
重复性经颅磁刺激(rTMS)是将局部脉冲磁场集中应用于大脑皮层,产生小电流,刺激大脑中参与情绪调节和抑郁的区域的神经细胞。与电休克疗法(ECT)类似,它是非侵入性的,但与ECT不同,它不涉及使用麻醉剂、癫痫诱导或意识丧失。澳大利亚和新西兰皇家精神病学院的专业实践指南(PPG 16)以及英国国家临床卓越研究所的介入程序指南[IPG542]都将抑郁症列为rTMS的主要临床指征。PPG 16还指出,有越来越多的证据表明rTMS在强迫症中的应用,但考虑到不同研究中使用的治疗靶点和模式多种多样,仍然很难得出全面的结论。该指南强调,在精神分裂症中使用rTMS的证据不太具有实质性,缺乏多中心试验,但可以考虑用于尽管有最佳药物治疗但仍有持续幻听的患者,并接受专家培训。
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引用次数: 0
Betel-quid use and its effects on symptoms of schizophrenia and extrapyramidal symptoms among a group of patients in a tertiary care hospital in Sri Lanka 在斯里兰卡一家三级保健医院的一组患者中,槟榔液的使用及其对精神分裂症和锥体外系症状的影响
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8244
A. Isuru, D. Ediriweera, A. Pathmeswaran, A. Embuldeniya, H. Narammalage, S. Warnakulasuriya, K. Kuruppuarachchi, A. Hapangama
Background There is limited research regarding the prevalence of betel quid use and its effects on symptoms of patients with schizophrenia. Available studies suggest an association between betel chewing and positive symptoms among males with schizophrenia. Aims This study aimed to compare the prevalence of betel quid chewing between patients with and without mental illness, and to explore the association between betel quid use, symptoms of schizophrenia and side effects of psychotropic medication. Methods A cross sectional descriptive study was carried atoutpatient clinics at a tertiary care hospital in Sri Lanka. A structured interview schedule was administered to all participants. Results Out of 1000 participants, 20.9% chewed betel quid (95%CI: 18.4% - 23.4%). The rate of betel chewing among patients with and without a mental illness was 20.7% (95% CI: 17.0% - 24.4%) and 21.0% (95% CI: 17.6% - 24.5%) respectively and there was no significant difference between the two groups. There was no statistically significant difference between the occurrence of positive or negative symptoms and extra pyramidal side effects in patients with schizophrenia who did and did not chew betel. Female gender (p=0.004) and betel quid chewing (0.002) were associated with more anticholinergic side effects. Conclusions There was no association between betel quid usage and the occurrence of positive or negative symptoms of schizophrenia or extra pyramidal side effects.
背景关于使用槟榔液的患病率及其对精神分裂症患者症状的影响的研究有限。现有研究表明,男性精神分裂症患者嚼槟榔与阳性症状之间存在关联。目的本研究旨在比较有和无精神疾病患者咀嚼槟榔液的患病率,并探讨槟榔液的使用、精神分裂症症状和精神药物副作用之间的关系。方法对斯里兰卡一家三级护理医院的门诊病人进行横断面描述性研究。所有参与者都有一个结构化的面试时间表。结果在1000名参与者中,嚼槟榔液的比例为20.9%(95%CI:18.4%-23.4%),有精神疾病和无精神疾病患者嚼槟榔的比例分别为20.7%(95%CI:17.0%-24.4%)和21.0%(95%CI:17.6%-24.5%),两组之间无显著差异。在咀嚼和不咀嚼槟榔的精神分裂症患者中,阳性或阴性症状的发生与锥体外副作用之间没有统计学上的显著差异。女性(p=0.004)和嚼槟榔液(0.002)与更多的抗胆碱能副作用有关。结论槟榔液的使用与精神分裂症阳性或阴性症状或锥体外副作用的发生无关。
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引用次数: 1
Association between obesity and attention deficit hyperactivity disorder in children at a tertiary care outpatient setting: A comparative study 三级保健门诊儿童肥胖与注意缺陷多动障碍的关系:一项比较研究
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8226
A. Ellepola, G. S. Wijethunge, N. Gunawardena
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引用次数: 1
Psychological effects of boarding students in schools far away from home – a qualitative study of a sample of students referred to a psychiatry clinic from Central Sri Lanka 离家很远的寄宿学生的心理影响——对斯里兰卡中部一家精神病学诊所转诊学生样本的定性研究
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8223
A. Malalagama
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引用次数: 0
Party drug to mainstream medicine; the transition of ketamine 党药走向主流医学;氯胺酮的转变
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8240
N. Ravindran, A. Ravindran
A significant proportion of patients with major depressive disorder are refractory to approved interventions. The first report of significant and rapid benefit of intravenous (IV) ketamine for treatment resistant depression (TRD) appeared in 2000. Since then, there have been multiple reports on the efficacy and tolerability of ketamine formulations for TRD, in particular for single-dose IV administration, which is supported by meta-analyses. The benefit for oral and other non-IV forms remains preliminary. There is preliminary evidence that ketamine has anti-suicidal properties. The adverse effects of ketamine are often mild, brief, and not clinically significant, and include dissociation, sedation, and changes in blood pressure and heart rate. Recently, the S-enantiomer esketamine has been developed, evaluated, and approved for use in North America as adjunct to antidepressants for TRD. Intranasal esketamine has ease of use but the IV form has the advantage of cost. Both are equally effective and tolerable with few drug interactions, and are indicated for adult patients with TRD. Informed consent, medical assessment, supervised setting and monitoring by trained personnel are mandatory. The increased risk of misuse, diversion, and addiction has been recognized with the need for education, responsible practice, and ongoing research.
很大一部分重性抑郁症患者对批准的干预措施难以治愈。静脉(IV)氯胺酮治疗难治性抑郁症(TRD)显著和快速获益的第一份报告出现在2000年。从那时起,有多篇关于氯胺酮制剂治疗TRD的疗效和耐受性的报告,特别是单剂量静脉给药,这些报告得到了荟萃分析的支持。口服和其他非静脉注射形式的益处仍处于初步阶段。有初步证据表明氯胺酮具有抗自杀的特性。氯胺酮的不良反应通常是轻微的、短暂的、没有临床意义的,包括游离、镇静、血压和心率的变化。最近,s -对映体艾氯胺酮已被开发、评估并批准在北美作为抗抑郁药辅助治疗TRD。鼻用艾氯胺酮易于使用,但静脉注射形式具有成本优势。这两种药物都是同样有效和耐受的,几乎没有药物相互作用,适用于成年TRD患者。知情同意、医疗评估、由训练有素的人员进行监督和监测是强制性的。滥用、转移和成瘾风险的增加已被认识到需要进行教育、负责任的实践和持续的研究。
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引用次数: 0
Prevalence and factors associated with mental health problems among children with asthma: a hospital-based study 哮喘儿童心理健康问题的患病率及相关因素:一项基于医院的研究
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8237
D. Dahanayake, G. S. Wijethunge, V. A. D. Silva
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引用次数: 0
Expressed emotion, medication adherence and association with disease prognosis in patients with schizophrenia at Teaching Hospital, Anuradhapura 阿努拉德普勒教学医院精神分裂症患者的情绪表达、药物依从性与疾病预后的关系
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8225
A. Ellepola, C. Abayaweera
Introduction Expressed emotion (EE) describes the caregiver’s attitudes and behaviour towards a person with a mental illness and is comprised of criticism, hostility and emotional overinvolvement (1). High EE has a direct association with recurrence of wide range of mental illness, especially schizophrenia (2). Significant behavioural deterioration has been reported in patients with schizophrenia who live with even minimally hostile relatives (2). Evidence shows that patients with schizophrenia returning home from the hospital to live Abstract
引言表达情感(EE)描述了照顾者对精神疾病患者的态度和行为,包括批评、敌意和情绪过度(1)。高EE与广泛的精神疾病,特别是精神分裂症的复发直接相关(2)。据报道,与敌对程度最低的亲属生活在一起的精神分裂症患者的行为严重恶化(2)。证据显示精神分裂症患者从医院回家生活摘要
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引用次数: 1
Stigma related to mental health issues – a study among adolescents in Sri Lanka 与心理健康问题有关的耻辱——斯里兰卡青少年研究
Pub Date : 2020-06-18 DOI: 10.4038/sljpsyc.v11i1.8243
U. Attygalle, H. Perera, B. D. W. Jayamanne
One definition of stigma is that it is a “collection of negative attitudes, beliefs, thoughts, and behaviours that influence the individual or the general public to fear, reject, avoid, be prejudiced, and discriminate against people” (1). Stigma impedes treatment seeking, erodes self-esteem and limits the individual’s social network. Although stigma was described as a unitary characteristic in earlier studies, currently it is understood as being more complex and having many dimensions and attributes (2-4). Culture also influences the way stigma relating to mental illness is presented (5).
耻辱感的一个定义是,它是“影响个人或公众恐惧、拒绝、回避、偏见和歧视他人的负面态度、信仰、思想和行为的集合”(1)。耻辱感阻碍了寻求治疗,侵蚀了自尊,限制了个人的社会网络。尽管在早期的研究中,柱头被描述为一种单一的特征,但目前人们认为它更复杂,具有许多维度和属性(2-4)。文化也影响了与精神疾病相关的耻辱的呈现方式(5)。
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引用次数: 1
期刊
Sri Lanka Journal of Psychiatry
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