A woman in her 70s with a large abdominal mass was admitted to another hospital, presenting with general malaise, poor appetite, weight loss, and night sweats. Abdominal computed tomography (CT) revealed homogeneously and mildly enhancing retroperitoneal tumor extending to the renal hilum and sinus along the urinary tract, causing peripheral compression of the normal renal parenchyma. A percutaneous renal biopsy under sonographic guidance confirmed the diagnosis of diffuse large B-cell lymphoma. A follow-up CT scan performed at our hospital revealed further enlargement of the lymphoma and the presence of a postbiopsy hematoma in the posterior pararenal space; however, no renal artery pseudoaneurysm was identified at that time (12 days after the biopsy). Four days after initiating chemotherapy—corresponding to 16 days after the biopsy—the patient developed abdominal pain and gross hematuria, progressing to shock. Emergency CT revealed a hematoma within the right urinary tract and a renal artery pseudoaneurysm located in the renal sinus, coinciding with marked regression of the lymphoma. Transcatheter arterial embolization was performed, and the renal artery pseudoaneurysm was successfully embolized using microcoils.
{"title":"Renal artery pseudoaneurysm following tumor biopsy: Delayed rupture shortly after commencing chemotherapy for malignant lymphoma","authors":"Tomonori Matsuura MD, Satoru Yanagaki MD, Yuriko Kagaya MD, Tomomi Sato MD, Nozomi Satani MD, Hiroshi Fukuda MD, Takayuki Yamada MD","doi":"10.1016/j.radcr.2025.10.005","DOIUrl":"10.1016/j.radcr.2025.10.005","url":null,"abstract":"<div><div>A woman in her 70s with a large abdominal mass was admitted to another hospital, presenting with general malaise, poor appetite, weight loss, and night sweats. Abdominal computed tomography (CT) revealed homogeneously and mildly enhancing retroperitoneal tumor extending to the renal hilum and sinus along the urinary tract, causing peripheral compression of the normal renal parenchyma. A percutaneous renal biopsy under sonographic guidance confirmed the diagnosis of diffuse large B-cell lymphoma. A follow-up CT scan performed at our hospital revealed further enlargement of the lymphoma and the presence of a postbiopsy hematoma in the posterior pararenal space; however, no renal artery pseudoaneurysm was identified at that time (12 days after the biopsy). Four days after initiating chemotherapy—corresponding to 16 days after the biopsy—the patient developed abdominal pain and gross hematuria, progressing to shock. Emergency CT revealed a hematoma within the right urinary tract and a renal artery pseudoaneurysm located in the renal sinus, coinciding with marked regression of the lymphoma. Transcatheter arterial embolization was performed, and the renal artery pseudoaneurysm was successfully embolized using microcoils.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 548-552"},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dynamic chest radiography is a bedside, low-dose X-ray technique that captures sequential images to visualize respiratory and cardiovascular motion and to derive ventilation maps. We present a case series of 4 patients with wheezing-associated acute respiratory failure from diverse etiologies (presumed asthma exacerbation, tracheobronchomalacia, cardiogenic pulmonary edema, and endotracheal mucus plugging). In each case, dynamic chest radiography provided real-time functional information that complemented initial evaluations when conventional tests were inconclusive. It suggested diffuse airflow limitation in the presumed asthma case, demonstrated expiratory central airway collapse in tracheobronchomalacia, supported pulmonary congestion without ventilation loss in heart failure, and revealed unilateral ventilation impairment due to mucus plugging in an intubated patient. These findings informed bedside clinical decision-making. Dynamic chest radiography may serve as a practical adjunct that increases diagnostic confidence in emergency and critical care settings where rapid, noninvasive functional assessment is desirable.
{"title":"Dynamic chest radiography for wheezing-associated acute respiratory failure: 4 case reports","authors":"Hidemitsu Miyatake MD, PhD , Masafumi Toshimitu MD , Shina Nakano MD , Junji Shimizu MD, PhD , Yasuyuki Tsujita MD, PhD , Kohei Asada MD, PhD , Naoto Shiomi PhD","doi":"10.1016/j.radcr.2025.10.012","DOIUrl":"10.1016/j.radcr.2025.10.012","url":null,"abstract":"<div><div>Dynamic chest radiography is a bedside, low-dose X-ray technique that captures sequential images to visualize respiratory and cardiovascular motion and to derive ventilation maps. We present a case series of 4 patients with wheezing-associated acute respiratory failure from diverse etiologies (presumed asthma exacerbation, tracheobronchomalacia, cardiogenic pulmonary edema, and endotracheal mucus plugging). In each case, dynamic chest radiography provided real-time functional information that complemented initial evaluations when conventional tests were inconclusive. It suggested diffuse airflow limitation in the presumed asthma case, demonstrated expiratory central airway collapse in tracheobronchomalacia, supported pulmonary congestion without ventilation loss in heart failure, and revealed unilateral ventilation impairment due to mucus plugging in an intubated patient. These findings informed bedside clinical decision-making. Dynamic chest radiography may serve as a practical adjunct that increases diagnostic confidence in emergency and critical care settings where rapid, noninvasive functional assessment is desirable.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 514-520"},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.1016/j.radcr.2025.10.050
Mohammed M. Kanani MS , Sara Haseli MD , Majid Chalian MD
Tenosynovial giant cell tumor is a rare, generally benign soft tissue lesion arising from the synovial lining of joints, bursae, or tendon sheaths. It most commonly presents as a solitary, localized mass in the small joints of the hands and feet. Diagnosis can be difficult due to clinical overlap with other soft tissue masses. Imaging and histopathologic confirmation are critical for diagnosis, while management decisions are guided by considerations of tumor extent, symptom burden, and patient preference, with close follow-up to monitor progression. Surgical excision remains the standard treatment; however, observation may be appropriate in select cases with minimal functional impairment. This case illustrates a rare presentation in a 56-year-old male with multifocal involvement of noncontiguous digits and highlights the importance of clinical awareness of unusual presentations and supporting individualized treatment planning.
{"title":"Multifocal tenosynovial giant cell tumor: A case report","authors":"Mohammed M. Kanani MS , Sara Haseli MD , Majid Chalian MD","doi":"10.1016/j.radcr.2025.10.050","DOIUrl":"10.1016/j.radcr.2025.10.050","url":null,"abstract":"<div><div>Tenosynovial giant cell tumor is a rare, generally benign soft tissue lesion arising from the synovial lining of joints, bursae, or tendon sheaths. It most commonly presents as a solitary, localized mass in the small joints of the hands and feet. Diagnosis can be difficult due to clinical overlap with other soft tissue masses. Imaging and histopathologic confirmation are critical for diagnosis, while management decisions are guided by considerations of tumor extent, symptom burden, and patient preference, with close follow-up to monitor progression. Surgical excision remains the standard treatment; however, observation may be appropriate in select cases with minimal functional impairment. This case illustrates a rare presentation in a 56-year-old male with multifocal involvement of noncontiguous digits and highlights the importance of clinical awareness of unusual presentations and supporting individualized treatment planning.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 536-542"},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.1016/j.radcr.2025.10.068
John Cacciatore BS, Stephanie Gonzalez BS, Kenneth Briley MD, Syed Ali MD, Maria Del Pilar Bayona Molano MD, Neal Viradia MD
Despite their rarity, hepatic artery pseudoaneurysms present a major risk to patients associated with high mortality. Effective, timely treatment is crucial. Options include percutaneous, endovascular, and surgical management. The first case involved a 68-year-old female with a fusiform pseudoaneurysm at the bifurcation of the common hepatic into the proper hepatic artery and the gastroduodenal arteries. Onyx (ev3,Plymouth,MN) was used to reconstruct the vessel lumen while angiography confirmed embolization of the pseudoaneurysm and arterial patency. Postoperatively, the Hgb stabilized with discharge 5 days later. The second case involved a 45-year-old male with nausea, emesis, pain, elevated liver function tests, and a pseudoaneurysm of the proper hepatic artery seen on imaging. Balloon occlusion was performed for 50 minutes until complete thrombosis. This method was only feasible due to the dual blood supply of the liver. Postoperatively, the abdominal pain immediately resolved and liver enzymes returned to baseline with discharge 2 days later. Being both rare and deadly, effective treatments of hepatic artery pseudoaneurysms are necessary, but novel treatments are seldom documented. Here 2 cases are described: vessel reconstruction with Onyx and Prolonged Balloon Occlusion. Both proved to be effective. Future studies should investigate additional options.
{"title":"Hepatic artery pseudoaneurysms: Two cases, 2 novel solutions, and a brief review of current treatments","authors":"John Cacciatore BS, Stephanie Gonzalez BS, Kenneth Briley MD, Syed Ali MD, Maria Del Pilar Bayona Molano MD, Neal Viradia MD","doi":"10.1016/j.radcr.2025.10.068","DOIUrl":"10.1016/j.radcr.2025.10.068","url":null,"abstract":"<div><div>Despite their rarity, hepatic artery pseudoaneurysms present a major risk to patients associated with high mortality. Effective, timely treatment is crucial. Options include percutaneous, endovascular, and surgical management. The first case involved a 68-year-old female with a fusiform pseudoaneurysm at the bifurcation of the common hepatic into the proper hepatic artery and the gastroduodenal arteries. Onyx (ev3,Plymouth,MN) was used to reconstruct the vessel lumen while angiography confirmed embolization of the pseudoaneurysm and arterial patency. Postoperatively, the Hgb stabilized with discharge 5 days later. The second case involved a 45-year-old male with nausea, emesis, pain, elevated liver function tests, and a pseudoaneurysm of the proper hepatic artery seen on imaging. Balloon occlusion was performed for 50 minutes until complete thrombosis. This method was only feasible due to the dual blood supply of the liver. Postoperatively, the abdominal pain immediately resolved and liver enzymes returned to baseline with discharge 2 days later. Being both rare and deadly, effective treatments of hepatic artery pseudoaneurysms are necessary, but novel treatments are seldom documented. Here 2 cases are described: vessel reconstruction with Onyx and Prolonged Balloon Occlusion. Both proved to be effective. Future studies should investigate additional options.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 526-531"},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Direct aneurysm or superior gluteal artery puncture is an alternative approach for internal iliac artery aneurysms after endovascular aneurysm repair. A 76-year-old man underwent endovascular aneurysm repair and bilateral internal iliac artery embolization for bilateral internal and right common iliac artery aneurysms. During the follow-up, the coils in the left internal iliac artery were recanalized, resulting in type 2 endoleak and the aneurysm enlarged. As standard antegrade or collateral access was impossible, percutaneous retrograde transgluteal inferior gluteal artery access was performed above the acetabulum with the patient in the prone position, followed by successful embolization of the internal iliac artery and aneurysm sac. Access-site hemostasis was achieved via manual compression. This access just above the acetabulum enabling stable manual compression could provide a safe option.
{"title":"Novel inferior gluteal artery access for successful type 2 endoleak embolization enabling the access site hemostasis by manual compression: A case report","authors":"Ryo Ogawa MD , Masashi Tamura MD, PhD , Taku Fujii MD, PhD , Jitsuro Tsukada MD, PhD , Atsunori Asami MD, PhD , Kiyoshi Ohkuma MD , Seishi Nakatsuka MD, PhD , Masahiro Jinzaki MD, PhD","doi":"10.1016/j.radcr.2025.10.057","DOIUrl":"10.1016/j.radcr.2025.10.057","url":null,"abstract":"<div><div>Direct aneurysm or superior gluteal artery puncture is an alternative approach for internal iliac artery aneurysms after endovascular aneurysm repair. A 76-year-old man underwent endovascular aneurysm repair and bilateral internal iliac artery embolization for bilateral internal and right common iliac artery aneurysms. During the follow-up, the coils in the left internal iliac artery were recanalized, resulting in type 2 endoleak and the aneurysm enlarged. As standard antegrade or collateral access was impossible, percutaneous retrograde transgluteal inferior gluteal artery access was performed above the acetabulum with the patient in the prone position, followed by successful embolization of the internal iliac artery and aneurysm sac. Access-site hemostasis was achieved via manual compression. This access just above the acetabulum enabling stable manual compression could provide a safe option.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 543-547"},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chudley-McCullough syndrome (CMS) is a rare autosomal recessive disorder. It is characterized by the association of early-onset sensorineural hearing loss and typical brain malformations, in contrast with preserved or only mildly affected psychomotor development. The first cases were reported in 1997 by Chudley et al. in a brother and sister born to consanguineous parents. It was not until 2012 that Doherty et al. identified mutations in the GPSM2 gene (G-protein signaling modulator 2) as the cause of CMS. We present the case of CMS in a 3-year-old girl with bilateral sensorineural deafness and characteristic brain malformations on MRI (callosal splenium agenesis, colpocephaly, interhemispheric cyst, cerebellar dysplasia, midline polymicrogyria and gray matter heterotopia).
{"title":"Chudley-McCullough syndrome: A report of a rare syndromic sensorineural hearing loss","authors":"Chaimae Ouqlani MD, Nourrelhouda Bahlouli MD, Hafsa Riache MD, Meryem Fikri PhD, Najwa Ech-cherif Kettani PhD, Mohamed Jiddane PhD, Firdaous Touarsa PhD","doi":"10.1016/j.radcr.2025.10.006","DOIUrl":"10.1016/j.radcr.2025.10.006","url":null,"abstract":"<div><div>Chudley-McCullough syndrome (CMS) is a rare autosomal recessive disorder. It is characterized by the association of early-onset sensorineural hearing loss and typical brain malformations, in contrast with preserved or only mildly affected psychomotor development. The first cases were reported in 1997 by Chudley et al. in a brother and sister born to consanguineous parents. It was not until 2012 that Doherty et al. identified mutations in the GPSM2 gene (G-protein signaling modulator 2) as the cause of CMS. We present the case of CMS in a 3-year-old girl with bilateral sensorineural deafness and characteristic brain malformations on MRI (callosal splenium agenesis, colpocephaly, interhemispheric cyst, cerebellar dysplasia, midline polymicrogyria and gray matter heterotopia).</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 509-513"},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.1016/j.radcr.2025.10.046
Ashley Park MD, Daniel Masri MD
Traumatic Basal Ganglia Hemorrhage has been rarely reported in the pediatric population. This case describes a 22 month old male who suffered a closed head injury following a motor vehicle accident and subsequently developed a basal ganglia hemorrhage. Unilateral basal ganglia hemorrhage with associated diffuse axonal injury in the corpus callosum and the grey white matter interface were visualized in magnetic resonance imaging and series of computed tomography. The patient was managed conservatively and discharged to a rehabilitation facility with minimal deficits. In summary, this case discusses the clinical and radiological prognosis of traumatic basal ganglia hemorrhage in the pediatric population.
{"title":"Traumatic basal ganglia hemorrhage in the pediatric population","authors":"Ashley Park MD, Daniel Masri MD","doi":"10.1016/j.radcr.2025.10.046","DOIUrl":"10.1016/j.radcr.2025.10.046","url":null,"abstract":"<div><div>Traumatic Basal Ganglia Hemorrhage has been rarely reported in the pediatric population. This case describes a 22 month old male who suffered a closed head injury following a motor vehicle accident and subsequently developed a basal ganglia hemorrhage. Unilateral basal ganglia hemorrhage with associated diffuse axonal injury in the corpus callosum and the grey white matter interface were visualized in magnetic resonance imaging and series of computed tomography. The patient was managed conservatively and discharged to a rehabilitation facility with minimal deficits. In summary, this case discusses the clinical and radiological prognosis of traumatic basal ganglia hemorrhage in the pediatric population.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 532-535"},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.1016/j.radcr.2025.10.049
Omer H. Ghalib PhD , Rawa Bapir PhD , Hemin A. Hassan PhD , Las L. Hussain PhD , Deari A. Ismaeil PhD , Soran H. Tahir PhD , Kayhan A. Najar BSc , Jihad I. Hama MSc , Hiwa O. Abdullah BSc , Fahmi H. Kakamad PhD
Retroperitoneal cavernous hemangiomas (RCHs) are exceedingly rare benign vascular tumors. They pose significant diagnostic challenges due to their nonspecific clinical presentations and imaging findings. This report highlights a clinically misdiagnosed case of RCH as a different retroperitoneal tumor. A 43-year-old female presented with persistent right hypochondrial pain. Imaging studies suggested a retroperitoneal mass, initially suspected to be either a gastrointestinal stromal tumor (GIST) or Schwannoma, or paraganglioma. Surgical resection of the tumor was performed, and histopathological examination confirmed the diagnosis of a cavernous hemangioma. The patient recovered well with no postoperative complications. Limited cases of RCHs have been reported in the literature. These tumors often mimic other retroperitoneal masses such as GISTs. Imaging findings are nonspecific, and definitive diagnosis typically relies on histopathological analysis. Surgical resection is the mainstay of treatment, with excellent outcomes reported across cases.
{"title":"Retroperitoneal cavernous hemangioma: A case report with literature review","authors":"Omer H. Ghalib PhD , Rawa Bapir PhD , Hemin A. Hassan PhD , Las L. Hussain PhD , Deari A. Ismaeil PhD , Soran H. Tahir PhD , Kayhan A. Najar BSc , Jihad I. Hama MSc , Hiwa O. Abdullah BSc , Fahmi H. Kakamad PhD","doi":"10.1016/j.radcr.2025.10.049","DOIUrl":"10.1016/j.radcr.2025.10.049","url":null,"abstract":"<div><div>Retroperitoneal cavernous hemangiomas (RCHs) are exceedingly rare benign vascular tumors. They pose significant diagnostic challenges due to their nonspecific clinical presentations and imaging findings. This report highlights a clinically misdiagnosed case of RCH as a different retroperitoneal tumor. A 43-year-old female presented with persistent right hypochondrial pain. Imaging studies suggested a retroperitoneal mass, initially suspected to be either a gastrointestinal stromal tumor (GIST) or Schwannoma, or paraganglioma. Surgical resection of the tumor was performed, and histopathological examination confirmed the diagnosis of a cavernous hemangioma. The patient recovered well with no postoperative complications. Limited cases of RCHs have been reported in the literature. These tumors often mimic other retroperitoneal masses such as GISTs. Imaging findings are nonspecific, and definitive diagnosis typically relies on histopathological analysis. Surgical resection is the mainstay of treatment, with excellent outcomes reported across cases.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 521-525"},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.radcr.2025.10.067
Daniel C. Fong BS , Wiktoria A. Gocal MD , Amal Isaiah MD, PhD, MBA
Sickle cell disease (SCD) is characterized by vaso-occlusive crises (VOC) that typically affect bones with high marrow content. Orbital involvement is rare, observed more frequently in children due to their greater marrow space and rich vascularization. Orbital VOC can clinically and radiologically mimic orbital abscesses, posing significant diagnostic challenges. We present a case of a 6-year-old boy with SCD who developed an orbital VOC initially mimicking an orbital abscess. The patient presented with 4 days of progressive right eye swelling and systemic inflammatory signs. A contrast-enhanced computed tomography demonstrated findings suggestive of subperiosteal abscess, preseptal abscess, subdural empyema, and sinusitis. Subsequent magnetic resonance imaging showed features that could represent either an orbital hematoma or abscess formation. Given the constellation of clinical and radiologic findings suggesting infection with potential intracranial extension, the patient underwent urgent surgical intervention including right craniotomy, right orbitotomy, and nasal endoscopy. Intraoperative drainage revealed dark red-brown fluid without purulence. Surgical pathology demonstrated necrotic fibrovascular tissue with brisk neovascularization, consistent with an organizing hematoma. Cultures remained negative. The final diagnosis was orbital hematoma secondary to vaso-occlusive infarction of orbital bone marrow despite the initial suspicion of an abscess. This case illustrates how orbital VOC in children with SCD can radiologically and clinically mimic an orbital abscess, necessitating a multidisciplinary evaluation to resolve the complicated diagnostic picture. It emphasizes the importance of maintaining a broad differential diagnosis in pediatric SCD patients presenting with orbital findings, particularly when systemic inflammation confounds radiologic interpretation.
{"title":"Orbital vaso-occlusive crisis mimicking an abscess in pediatric sickle cell disease: A diagnostic pitfall","authors":"Daniel C. Fong BS , Wiktoria A. Gocal MD , Amal Isaiah MD, PhD, MBA","doi":"10.1016/j.radcr.2025.10.067","DOIUrl":"10.1016/j.radcr.2025.10.067","url":null,"abstract":"<div><div>Sickle cell disease (SCD) is characterized by vaso-occlusive crises (VOC) that typically affect bones with high marrow content. Orbital involvement is rare, observed more frequently in children due to their greater marrow space and rich vascularization. Orbital VOC can clinically and radiologically mimic orbital abscesses, posing significant diagnostic challenges. We present a case of a 6-year-old boy with SCD who developed an orbital VOC initially mimicking an orbital abscess. The patient presented with 4 days of progressive right eye swelling and systemic inflammatory signs. A contrast-enhanced computed tomography demonstrated findings suggestive of subperiosteal abscess, preseptal abscess, subdural empyema, and sinusitis. Subsequent magnetic resonance imaging showed features that could represent either an orbital hematoma or abscess formation. Given the constellation of clinical and radiologic findings suggesting infection with potential intracranial extension, the patient underwent urgent surgical intervention including right craniotomy, right orbitotomy, and nasal endoscopy. Intraoperative drainage revealed dark red-brown fluid without purulence. Surgical pathology demonstrated necrotic fibrovascular tissue with brisk neovascularization, consistent with an organizing hematoma. Cultures remained negative. The final diagnosis was orbital hematoma secondary to vaso-occlusive infarction of orbital bone marrow despite the initial suspicion of an abscess. This case illustrates how orbital VOC in children with SCD can radiologically and clinically mimic an orbital abscess, necessitating a multidisciplinary evaluation to resolve the complicated diagnostic picture. It emphasizes the importance of maintaining a broad differential diagnosis in pediatric SCD patients presenting with orbital findings, particularly when systemic inflammation confounds radiologic interpretation.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 500-504"},"PeriodicalIF":0.0,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.radcr.2025.10.038
Katherine H Belanger MD , Carol P Geer MD , Tyler P Grande , E Andrew Stevens MD
Capillary hemangiomas are benign vascular lesions that frequently involve the soft tissues of the head and neck. Less commonly, these lesions can be found along the spinal neuroaxis. The differential diagnosis of a spinal intradural extramedullary lesion is led by meningioma and nerve sheath tumors. We present the case of a spinal capillary hemangioma mimicking a spinal meningioma and suggest this pathology should be considered in the differential diagnosis of similar lesions in the spinal intradural extramedullary space. This diagnostic consideration is important as it may impact treatment planning, surgical decision making, and complication avoidance.
{"title":"Intradural spinal capillary hemangioma mimicking thoracic meningioma","authors":"Katherine H Belanger MD , Carol P Geer MD , Tyler P Grande , E Andrew Stevens MD","doi":"10.1016/j.radcr.2025.10.038","DOIUrl":"10.1016/j.radcr.2025.10.038","url":null,"abstract":"<div><div>Capillary hemangiomas are benign vascular lesions that frequently involve the soft tissues of the head and neck. Less commonly, these lesions can be found along the spinal neuroaxis. The differential diagnosis of a spinal intradural extramedullary lesion is led by meningioma and nerve sheath tumors. We present the case of a spinal capillary hemangioma mimicking a spinal meningioma and suggest this pathology should be considered in the differential diagnosis of similar lesions in the spinal intradural extramedullary space. This diagnostic consideration is important as it may impact treatment planning, surgical decision making, and complication avoidance.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 2","pages":"Pages 505-508"},"PeriodicalIF":0.0,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}