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Comparing Effects of Cryotherapy and Transcutaneous Electrical Nerve Stimulation on Signs and Symptoms of Delayed Onset Muscle Soreness in Amateur Athletes 冷冻疗法与经皮神经电刺激对业余运动员迟发性肌肉酸痛症状体征的比较
Q3 Medicine Pub Date : 2017-09-14 DOI: 10.2174/1876386301710010073
K. Malmir, N. Ghotbi, S. M. Mir, B. Moradi
Results: Two-factor repeated measures analysis of variance showed a significant main effect of time for pain intensity, AROM and triple hop distance(P<0.05), and main effect of group for pain intensity and AROM(P<0.05), and interaction effects of group×time for pain intensity and AROM(P<0.05). Post hoc statistical tests showed that mean of pain intensity and AROM was changed by cryotherapy group(P<0.017).
结果:双因素重复测量方差分析显示,时间对疼痛强度、AROM和三跳距离的主效应显著(P<0.05),组对疼痛强度和AROM的主效应明显(P<0.05),×时间对疼痛强度和AROM的交互作用(P<0.05)。
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引用次数: 9
Pain dreams and dream emotions in patients with chronic back pain and healthy controls 慢性背痛患者和健康对照者的疼痛梦和梦境情绪
Q3 Medicine Pub Date : 2017-08-15 DOI: 10.2174/1876386301710010065
M. Schredl, Aline Kälberer, K. Zacharowski, M. Zimmermann
Conclusion: In patients, pain dreams might be instigated by actual pain whereas for healthy persons pain dreams might be pain memories (selfexperienced pain and/or seeing persons in pain). Future research should clarify how pain is processed during sleep. As patients with chronic pain experience negatively toned dreams, it will be beneficial to ask chronic pain patients about their dreams and, if necessary, offer specific treatment options like imagery rehearsal treatment.
结论:患者的疼痛梦可能是由实际疼痛引起的,而健康人的疼痛梦则可能是疼痛记忆(亲身经历的疼痛和/或看到疼痛中的人)。未来的研究应该阐明睡眠中疼痛是如何处理的。由于慢性疼痛患者会经历负面的梦境,询问慢性疼痛患者的梦境情况将是有益的,如有必要,可以提供特定的治疗选择,如图像排练治疗。
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引用次数: 4
Turkish Pediatric Nurses’ Use of Non-Pharmacological Methods for Postoperative Pain Relief in 6 to 12 Year Old Children 土耳其儿科护士使用非药理学方法缓解6-12岁儿童术后疼痛
Q3 Medicine Pub Date : 2017-07-31 DOI: 10.2174/1876386301710010056
E. Efe, Derya Özcan, Şevkiye Dikmen, Nuray Altaş
INTRODUCTION There have been numerous pediatric postoperative pain management studies over the past 20 years, yet children continue to experience avoidable postoperative pain [1 3]. Recent studies suggest that postoperative pain in children is often poorly managed [4 7]. The reasons for this may include nurses’ undermedicating for postoperative pain despite adequate prescription, nurses’ inadequate pain assessment and monitoring, and inadequate use of other pain relief methods due to lack of time, knowledge, skills, and organizational support [8 11]. Some European investigators reported, that nurses frequently use these methods [12,13] and another study showed, that nurses rarely use these methods to relieve pain [14]. Research focused on nurses’ use of non-pharmacological methods for pediatric postoperative pain relief has increased in the recent years. However, research evidence seems to be inconsistent. Non-pharmacological methods in children’s pain management can be classified as sensory or physical, cognitive and cognitive-behavioural interventions.
在过去的20年里,有大量的儿童术后疼痛管理研究,但儿童仍然经历着可避免的术后疼痛[13]。最近的研究表明,儿童术后疼痛往往管理不善[4 7]。造成这种情况的原因可能包括护士在处方充足的情况下对术后疼痛用药不足,护士对疼痛的评估和监测不足,以及由于缺乏时间、知识、技能和组织支持而没有充分使用其他疼痛缓解方法[8 11]。一些欧洲研究者报道,护士经常使用这些方法[12,13],而另一项研究表明,护士很少使用这些方法来缓解疼痛。近年来,关于护士使用非药物方法缓解儿科术后疼痛的研究有所增加。然而,研究证据似乎并不一致。儿童疼痛管理的非药物方法可分为感觉或身体、认知和认知行为干预。
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引用次数: 2
Effect of Age, Sex and Gender on Pain Sensitivity: A Narrative Review 年龄、性别和性别对疼痛敏感性的影响:一个叙述性的回顾
Q3 Medicine Pub Date : 2017-07-31 DOI: 10.2174/1876386301710010044
Hanan El-Tumi, O. Tashani
© 2017 Eltumi And Tashani. Introduction: An increasing body of literature on sex and gender differences in pain sensitivity has been accumulated in recent years. There is also evidence from epidemiological research that painful conditions are more prevalent in older people. The aim of this narrative review is to critically appraise the relevant literature investigating the presence of age and sex differences in clinical and experimental pain conditions. Methods: A scoping search of the literature identifying relevant peer reviewed articles was conducted on May 2016. Information and evidence from the key articles were narratively described and data was quantitatively synthesised to identify gaps of knowledge in the research literature concerning age and sex differences in pain responses. Results: This critical appraisal of the literature suggests that the results of the experimental and clinical studies regarding age and sex differences in pain contain some contradictions as far as age differences in pain are concerned. While data from the clinical studies are more consistent and seem to point towards the fact that chronic pain prevalence increases in the elderly findings from the experimental studies on the other hand were inconsistent, with pain threshold increasing with age in some studies and decreasing with age in others. Conclusion: There is a need for further research using the latest advanced quantitative sensory testing protocols to measure the function of small nerve fibres that are involved in nociception and pain sensitivity across the human life span. Implications: Findings from these studies should feed into and inform evidence emerging from other types of studies (e.g. brain imaging technique and psychometrics) suggesting that pain in the older humans may have unique characteristics that affect how old patients respond to intervention.
©2017 Eltumi和Tashani。引言:近年来,关于疼痛敏感性的性别和性别差异的文献越来越多。流行病学研究也有证据表明,疼痛的情况在老年人中更为普遍。这篇叙述性综述的目的是批判性地评价研究临床和实验疼痛条件下年龄和性别差异的相关文献。方法:2016年5月,对确定相关同行评审文章的文献进行了范围搜索。对关键文章中的信息和证据进行了叙述性描述,并对数据进行了定量综合,以确定研究文献中关于疼痛反应的年龄和性别差异的知识差距。结果:对文献的批判性评价表明,就疼痛的年龄差异而言,关于疼痛的年龄和性别差异的实验和临床研究结果存在一些矛盾。虽然临床研究的数据更加一致,似乎表明了一个事实,即老年人慢性疼痛患病率的增加,但另一方面,实验研究的结果并不一致,在一些研究中,疼痛阈值随着年龄的增长而增加,而在另一些研究中则随着年龄的增加而降低。结论:有必要使用最新的先进定量感觉测试方案进行进一步研究,以测量人类寿命中参与伤害感受和疼痛敏感性的小神经纤维的功能。影响:这些研究的结果应该为其他类型的研究(如脑成像技术和心理测量学)提供证据,表明老年人的疼痛可能具有影响老年患者对干预反应的独特特征。
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引用次数: 21
Rat Running Wheel Behavior Reflects Inflammatory, Orofacial Pain 大鼠跑轮行为反映炎症,口腔面部疼痛
Q3 Medicine Pub Date : 2017-07-21 DOI: 10.2174/1876386301710010037
P. Farrow, K. Rowland
Received: January 26, 2017 Revised: May 17, 2017 Accepted: June 01, 2017 Abstract: Background: Our objective was to establish a novel, unbiased metric of inflammatory, orofacial pain. Method: Rats were placed individually into cages equipped with running wheels, and allowed an acclimation period of 17 days. Diurnal and nocturnal voluntary running behaviors were recorded. After day 17, rats were deeply anesthetized and divided into mustard oil, vehicle (mineral oil) and drug (ibuprofen) groups. Injections of mustard oil or mineral oil were made into the vestibule superior to the maxillary molar. Running wheel behavior was recorded for three days following the procedure. Results: After acclimation, the average percentage of running behavior that occurred at night was 94% +/-1% SE. Mustard oil injections caused externally observable, unilateral inflammation. On average, mustard oil injections significantly reduced nocturnal running on the first and second nocturnal periods post-injection. The non-steroidal anti-inflammatory, ibuprofen, significantly improved running behavior during the second nocturnal period, which was abolished when removed during the third nocturnal period. Conclusions: We conclude that unilateral injections of algogens in the vestibule coupled with analysis of nocturnal running behavior is an effective method to measure acute inflammatory pain for three days that mirrors many painful clinical situations. The model could be used as inexpensive, quantitative method to evaluate putative pain relieving therapeutics.
接收时间:2017年1月26日修订日期:2017年5月17日接受日期:2017月1日摘要:背景:我们的目标是建立一种新的、无偏见的炎症性口面疼痛指标。方法:将大鼠单独放入装有转轮的笼子中,并允许17天的适应期。记录昼夜自主跑步行为。第17天后,将大鼠深度麻醉,并分为芥末油组、赋形剂组(矿物油)组和药物组(布洛芬)组。将芥末油或矿物油注入上颌磨牙上方的前庭。在手术后的三天内记录转轮的运行情况。结果:驯化后,夜间跑步行为的平均百分比为94%+/-1%SE。芥末油注射引起外部可观察到的单侧炎症。平均而言,在注射后的第一个和第二个夜间时段,芥末油注射显著减少了夜间跑步。非甾体抗炎药布洛芬在第二个夜间时段显著改善了跑步行为,在第三个夜间时段去除后,这种行为消失了。结论:我们得出的结论是,在前庭单侧注射麻醉剂,结合夜间跑步行为分析,是测量三天急性炎症疼痛的有效方法,反映了许多痛苦的临床情况。该模型可以作为一种廉价、定量的方法来评估公认的止痛疗法。
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引用次数: 0
Study of Evaluation of Symptoms of Juvenile Recurrent Parotitis Prior to and After Sialendoscopy 青少年复发性腮腺炎唾液酸造影前后症状评价的研究
Q3 Medicine Pub Date : 2017-06-30 DOI: 10.2174/1876386301710010029
B. Faizal, S. Abraham
RESEARCH ARTICLE Study of Evaluation of Symptoms of Juvenile Recurrent Parotitis Prior to and After Sialendoscopy Bini Faizal, Sania Mariam Abraham and Krishnakumar T Clinical Professor, Department of ENT, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeedham, Kochi Clinical Professor, Department of Head and Neck Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeedham, Kochi
研究文章Sialendoscopy Bini Faizal、Sania Mariam Abraham和Krishnakumar T临床教授、Amrita医学科学研究所耳鼻喉科Amrita Vishwa Vidyapeedham、Kochi临床教授、头颈外科Amrita医疗科学研究所,高知
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引用次数: 3
WHEN PAIN IS BEYOND BIOLOGY - A CASE OF FAKE LEPROSY 当疼痛超出生物学范围时——一例假麻风病
Q3 Medicine Pub Date : 2017-06-30 DOI: 10.2174/1876386301710010022
L. A. Ávila, Eurides de Oliveira Pozetti, Gislaine Fusco Fares, R. M. C. Soubhia, Marília Capuço Oliveira, Andreia Yumi Tomiyasu
Received: December 30, 2016 Revised: May 10, 2017 Accepted: May 17, 2017 Abstract: Background: Pain is a complex phenomenon that implies pathophysiological processes and psychosocial components. A 56-year-old female patient complaining of pain and presenting with multiple mild physical signs was examined by a multidisciplinary team from the EarNose-Throat, Dermatology, Hematology, General Clinics, and Psychiatry and Psychology Departments. Objective: To present a significant case where pain is primarily caused by psychological conflicts. Method: A multidisciplinary approach, with medical and psychological interventions. Results: The patient was deeply convinced; she had been contaminated by leprosy. Her enrooted personal beliefs, including religion and moral conflicts, seem to be the primary cause for her putative ‘disease’, a condition that was not confirmed by exhaustive exams. Conclusion: Pain normally is related to several factors, including biological, psychological and cultural. Some complex cases should be investigated by a multidisciplinary team of specialists, in order to identify extra-physiological components.
接收日期:2016年12月30日修订日期:2017年5月10日接受日期:2017月17日摘要:背景:疼痛是一种复杂的现象,包含病理生理过程和心理社会成分。一名56岁的女性患者抱怨疼痛并出现多种轻微体征,由耳鼻咽喉科、皮肤科、血液科、普通诊所、精神病学和心理学部门的多学科团队进行了检查。目的:提出一个主要由心理冲突引起疼痛的重要案例。方法:采用医学和心理干预的多学科方法。结果:患者深信不疑;她染上了麻风病。她根深蒂固的个人信仰,包括宗教和道德冲突,似乎是她假定的“疾病”的主要原因,这种情况没有通过详尽的检查得到证实。结论:疼痛通常与多种因素有关,包括生理、心理和文化因素。一些复杂的病例应由多学科专家团队进行调查,以确定额外的生理成分。
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引用次数: 0
Why do Pain Physicians Not Routinely Use Mixed Opioids for the Prevention of Neuraxial Opioid-induced Pruritus? 为什么疼痛医生不经常使用混合阿片类药物来预防神经轴阿片类诱导的瘙痒?
Q3 Medicine Pub Date : 2017-05-31 DOI: 10.2174/1876386301710010014
Borja Mugabure Bujedo
Received: December 20, 2016 Revised: February 14, 2017 Accepted: February 17, 2017 Abstract: Background: Pruritus is a very disturbing secondary effect that appears after epidural or intrathecal administration of opioid drugs, especially in the management of postoperative pain. It is induced by the activation of mu opioid receptors and it can often be even more unpleasant than the pain being treated.
接收日期:2016年12月20日修订日期:2017年2月14日接受日期:2017月17日摘要:背景:瘙痒是一种非常令人不安的副作用,在硬膜外或鞘内给药阿片类药物后出现,尤其是在术后疼痛的管理中。它是由μ阿片受体的激活引起的,通常比正在治疗的疼痛更令人不快。
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引用次数: 1
Physiotherapy Interventions and the Outcomes for Complex Regional Pain Syndrome (CRPS) Type 1 on the South Island of New Zealand – A Longitudinal, Prospective Case Series 新西兰南岛1型复杂区域性疼痛综合征(CRPS)的物理治疗干预和结果——纵向前瞻性病例系列
Q3 Medicine Pub Date : 2017-03-23 DOI: 10.2174/1876386301710010005
T. Pons, E. Shipton, J. Williman, R. Mulder
Physiotherapy is considered in pain medicine to be a key element in the management of Complex Regional Pain Syndrome (CRPS). This is the first paper to document and categorise all physiotherapy intervention methods used as well as evaluate the outcomes of a case series of 18 CRPS patients attending physiotherapy in a prospective, longitudinal study across a region. Outcomes were measured across the region of the South Island of New Zealand over 1 year through independent telephonic interviewing of the pain experience with the McGill Pain Questionnaire-short form, function with Foot Function Index for the lower limb or Disability of the Arm Shoulder and Hand for the upper limb, and quality of life with the World Health Organisation Disability Schedule. Clinical records were accessed for each CRPS participant following discharge from physiotherapy to categorise the intervention methods used. Seventeen participants received intervention for both functional restoration with pain modulation and only one participant received functional restoration with no pain modulation; 12 also received immobilisation with 10 receiving passive interventions. All outcome measures improved significantly by 6 months and were maintained at 1 year. Eighty five percent had their diagnosis of CRPS confirmed within 3 months of their injury; half had fracture as the precipitating injury for their onset of CRPS with a third following soft tissue injury and 11% following surgery. Physiotherapists showed a high variation with the intervention methods used and showed a greater proportion of intervention methods focusing on functional restoration followed by pain modulating interventions. Future research is necessary to define what physiotherapy interventions are efficacious in the management of CRPS.
在疼痛医学中,物理治疗被认为是复杂区域疼痛综合征(CRPS)治疗的关键因素。这是第一篇记录和分类所有使用的物理治疗干预方法的论文,并在一项跨地区的前瞻性纵向研究中评估了18名CRPS患者接受物理治疗的病例系列的结果。结果通过独立电话访谈在新西兰南岛地区测量了1年以上的疼痛经历,使用麦吉尔疼痛问卷(简短形式),下肢的功能与足功能指数或上肢的手臂、肩膀和手的残疾,以及世界卫生组织残疾时间表的生活质量。在物理治疗结束后,对每位CRPS参与者的临床记录进行访问,以对所使用的干预方法进行分类。17名参与者接受了功能恢复和疼痛调节的干预,只有1名参与者接受了功能恢复而没有疼痛调节;12人接受固定,10人接受被动干预。所有结局指标在6个月时均显著改善,并维持1年。85%的人在受伤后3个月内确诊为CRPS;一半的CRPS发病的诱发性损伤是骨折,三分之一是软组织损伤,11%是手术。物理治疗师在使用的干预方法上表现出很大的差异,并且显示出更大比例的干预方法侧重于功能恢复,然后是疼痛调节干预。未来的研究需要明确哪些物理治疗干预措施在治疗CRPS中是有效的。
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引用次数: 1
Antimicrobial activity of lidocaine, bupivacaine, mepivacaine and ropivacaine on Staphylococcus epidermidis, Staphylococcus aureus and Bacillus subtilis 利多卡因、布比卡因、甲哌卡因和罗哌卡因对表皮葡萄球菌、金黄色葡萄球菌和枯草芽孢杆菌的抗菌活性
Q3 Medicine Pub Date : 2017-02-28 DOI: 10.2174/1876386301710010001
S. Neuwersch, M. Köstenberger, S. Sorschag, W. Ilias, R. Likar
LETTER Antimicrobial Activity of Lidocaine, Bupivacaine, Mepivacaine and Ropivacaine on Staphylococcus epidermidis, Staphylococcus aureus and Bacillus subtilis S. Neuwersch, M. Köstenberger, S. Sorschag, W. Ilias and R. Likar Department of Anaesthesiology and Intensive Care, General Hospital Klagenfurt, Klagenfurt, Austria Institute of Laboratory Diagnostics and Microbiology, General Hospital Klagenfurt, Klagenfurt, Austria Vienna Private Clinic, Vienna, Austria
LETTER利多卡因、布比卡因、甲哌卡因和罗哌卡因对表皮葡萄球菌、金黄色葡萄球菌和枯草芽孢杆菌的抗菌活性。Neuwersch,M.Köstenberger,S.Sorschag,W.Ilias和R.Likar麻醉和重症监护科,克拉根福总医院,克拉根福德,奥地利实验室诊断和微生物学研究所,克拉根福综合医院,克拉根福,奥地利维也纳私人诊所,奥地利维也纳
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引用次数: 3
期刊
Open Pain Journal
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