Pub Date : 2021-12-09DOI: 10.4274/mjima.galenos.2021.2021.63
A. Aypak, E. Akıncı, A. Erden, Banu ÇAKIR TOPÇU, O. Küçükşahin, Rahmet Güner
Coronavirus disease-2019 (COVID-19) is a global health problem causing morbidity and mortality. It has a clinical spectrum ranging from an absence of symptoms to acute respiratory distress syndrome. A new COVID-19-related clinical finding is published daily. We report here a patient with COVID-19 and cerebral venous sinus thrombosis and no deep vein thrombosis or any underlying predisposing factors for hypercoagulation.
{"title":"COVID-19-Associated Cerebral Venous Sinus Thrombosis: A Case Report and Review of the Literature","authors":"A. Aypak, E. Akıncı, A. Erden, Banu ÇAKIR TOPÇU, O. Küçükşahin, Rahmet Güner","doi":"10.4274/mjima.galenos.2021.2021.63","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.63","url":null,"abstract":"Coronavirus disease-2019 (COVID-19) is a global health problem causing morbidity and mortality. It has a clinical spectrum ranging from an absence of symptoms to acute respiratory distress syndrome. A new COVID-19-related clinical finding is published daily. We report here a patient with COVID-19 and cerebral venous sinus thrombosis and no deep vein thrombosis or any underlying predisposing factors for hypercoagulation.","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"63 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84505876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-19DOI: 10.4274/mjima.galenos.2021.2020.59
Khaddouj Amzil, F. Hamadi, R. Mimouni, Aissa Saidi, K. Azelmad, Jaouad Abou Oualid, A. Laktib, Mariem Zanzan
{"title":"Single-and Dual-species Biofilm Formation of Pseudomonas aeruginosa and Staphylococcus sciuri on Catering Kitchen Surfaces in Health Establishments","authors":"Khaddouj Amzil, F. Hamadi, R. Mimouni, Aissa Saidi, K. Azelmad, Jaouad Abou Oualid, A. Laktib, Mariem Zanzan","doi":"10.4274/mjima.galenos.2021.2020.59","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2020.59","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"18 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84434103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.4274/mjima.galenos.2021.2021.62
Umay Balcı, Kübra Demir Önder, Ayşegül Seremet Keskin
Introduction: Clinical picture of Coronavirus disease-2019 (COVID-19) ranges from mild respiratory symptoms to severe respiratory failure and death. To determine the severity of the disease;lymphocyte count, lactate dehydrogenase (LDH), C-reactive protein (CRP), D-dimer and interleukin-6 (IL-6) levels are the parameters that are used. In this study, it was aimed to evaluate effect of LDH/lymphocyte ratio on prognosis and whether there was a correlation between LDH/lymphocyte ratio and IL-6 in hospitalized patients with COVID-19. Materials and Methods: Patients who were aged 18 years and older, were positive for Severe acute respiratory syndrome-Coronavirus-2 polymerase chain reaction test, had COVID-19 pneumonia findings on tomography, and hospitalized for at least three days were included in the study. Results: The mean age of the patients was 59.35±15.23 year and 56 (59.6%) of patients were male. Fifty seven (60.6%) of the patients had comorbid diseases. The 14- and 28-day mortality rates were 14.9% and 27.7%, respectively. There was a statistically significant correlation between hospitalization in intensive care unit and LDH, lymphocyte count, LDH/lymphocyte ratio, CRP, highest D-dimer, initial IL-6, neutrophil/lymphocyte ratio, and highest IL-6 values (p<0.05). The IL-6 level, highest D-dimer level, LDH/lymphocyte ratio and CRP level of the patients who died were significantly higher than those who were survivors (p<0.05). A positive and significant correlation was found between the LDH/lymphocyte ratio and both the first admission and the highest IL-6 levels. In ROC analysis, LDH/lymphocyte ratio values of 0.53 and above [AUC: 0.758 (95% CI: 0.660-0.855)] were found to have a specificity of 61% and sensitivity of 70.7% in showing the IL-6 level of 80 pg/ml and above at first admission. Conclusion: In this study, a significant correlation was found between the LDH/lymphocyte ratio and the IL-6 values. As a result of this study, even if IL-6 cannot be measured, the ratio of LDH/lymphocyte that can be measured in most centers, is thought to be an important marker in predicting poor clinical course.
{"title":"Evaluation of the Relationship Lactate Dehydrogenase/Lymphocyte Ratio with Interleukin-6 Value in Hospitalized Patients with COVID-19","authors":"Umay Balcı, Kübra Demir Önder, Ayşegül Seremet Keskin","doi":"10.4274/mjima.galenos.2021.2021.62","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.62","url":null,"abstract":"Introduction: Clinical picture of Coronavirus disease-2019 (COVID-19) ranges from mild respiratory symptoms to severe respiratory failure and death. To determine the severity of the disease;lymphocyte count, lactate dehydrogenase (LDH), C-reactive protein (CRP), D-dimer and interleukin-6 (IL-6) levels are the parameters that are used. In this study, it was aimed to evaluate effect of LDH/lymphocyte ratio on prognosis and whether there was a correlation between LDH/lymphocyte ratio and IL-6 in hospitalized patients with COVID-19. Materials and Methods: Patients who were aged 18 years and older, were positive for Severe acute respiratory syndrome-Coronavirus-2 polymerase chain reaction test, had COVID-19 pneumonia findings on tomography, and hospitalized for at least three days were included in the study. Results: The mean age of the patients was 59.35±15.23 year and 56 (59.6%) of patients were male. Fifty seven (60.6%) of the patients had comorbid diseases. The 14- and 28-day mortality rates were 14.9% and 27.7%, respectively. There was a statistically significant correlation between hospitalization in intensive care unit and LDH, lymphocyte count, LDH/lymphocyte ratio, CRP, highest D-dimer, initial IL-6, neutrophil/lymphocyte ratio, and highest IL-6 values (p<0.05). The IL-6 level, highest D-dimer level, LDH/lymphocyte ratio and CRP level of the patients who died were significantly higher than those who were survivors (p<0.05). A positive and significant correlation was found between the LDH/lymphocyte ratio and both the first admission and the highest IL-6 levels. In ROC analysis, LDH/lymphocyte ratio values of 0.53 and above [AUC: 0.758 (95% CI: 0.660-0.855)] were found to have a specificity of 61% and sensitivity of 70.7% in showing the IL-6 level of 80 pg/ml and above at first admission. Conclusion: In this study, a significant correlation was found between the LDH/lymphocyte ratio and the IL-6 values. As a result of this study, even if IL-6 cannot be measured, the ratio of LDH/lymphocyte that can be measured in most centers, is thought to be an important marker in predicting poor clinical course.","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"47 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80122579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-17DOI: 10.4274/mjima.galenos.2021.2021.61
S. Ermurat, K. Ayar, S. Avcı, Vildan Gürsoy
{"title":"Disease Course in Hospitalized COVID-19 Patients with and without Rheumatic Disease and Its Relationship with Immunosuppressive Drug Use","authors":"S. Ermurat, K. Ayar, S. Avcı, Vildan Gürsoy","doi":"10.4274/mjima.galenos.2021.2021.61","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.61","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"63 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82988698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-17DOI: 10.4274/mjima.galenos.2021.2021.60
Meltem Songur Kodik, Esin Öztürk, I. Uz, Enver Özçete, Özlem Inci, M. Ersel
{"title":"Evaluation of Mortality in ICU-admitted COVID-19 Patients Using Four Scoring Models: REMS, APACHE-II, CCI, and SOFA","authors":"Meltem Songur Kodik, Esin Öztürk, I. Uz, Enver Özçete, Özlem Inci, M. Ersel","doi":"10.4274/mjima.galenos.2021.2021.60","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.60","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"58 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84451900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-16DOI: 10.4274/mjima.galenos.2021.2021.57
A. Sertçelik, I. Baran, E. Akıncı, S. Kazancioglu, H. Bodur
{"title":"Evaluation of In Vitro Synergistic Activities of Some Antibiotic Combinations Containing Colistin, Meropenem, Vancomycin, and Minocycline against OXA-48 Carbapenemase-producing Klebsiella pneumoniae","authors":"A. Sertçelik, I. Baran, E. Akıncı, S. Kazancioglu, H. Bodur","doi":"10.4274/mjima.galenos.2021.2021.57","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.57","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"131 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85350144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-16DOI: 10.4274/mjima.galenos.2021.2021.55
Aylin Uskudar-Guclu, D. Şimşek, Ilgin Ata-Vural, Sezin Unlu, A. Basustaoglu
{"title":"Antibacterial, Antifungal and Antibiofilm Activity of Methylglyoxal: a Phytochemical from Manuka Honey","authors":"Aylin Uskudar-Guclu, D. Şimşek, Ilgin Ata-Vural, Sezin Unlu, A. Basustaoglu","doi":"10.4274/mjima.galenos.2021.2021.55","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.55","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"75 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80515376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-16DOI: 10.4274/mjima.galenos.2021.2021.58
İsa Ahmet Bal, A. Tartar, A. Akbulut, Kutbeddin Demirdağ
{"title":"Extrapulmonary Tuberculosis Cases: 5 Years Experience","authors":"İsa Ahmet Bal, A. Tartar, A. Akbulut, Kutbeddin Demirdağ","doi":"10.4274/mjima.galenos.2021.2021.58","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.58","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"10 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88477215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-16DOI: 10.4274/mjima.galenos.2021.2021.56
M. Ahmadi, N. Bolourchi, Z. Rezaei, F. Badmasti, M. Shafiei
{"title":"Nanoparticles: A Promising Treatment for Herpes simplex virus type-1 (HSV-1) Infections","authors":"M. Ahmadi, N. Bolourchi, Z. Rezaei, F. Badmasti, M. Shafiei","doi":"10.4274/mjima.galenos.2021.2021.56","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.56","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"148 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85265125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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