首页 > 最新文献

International Journal of Health and Allied Sciences最新文献

英文 中文
Diagnostically fighting the coronavirus disease 2019 pandemic: A general perspective 诊断对抗2019年冠状病毒病大流行:总体观点
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_217_20
P. Ramesh, Brunda Arun, Devananda Devegowda
The recent outbreak of severe acute respiratory syndrome-coronavirus 2 has brought human survival and existence to an all-time low. The infection seems to be uncontrollable, and the scientific community has no answer yet. The only means of keeping the infection under the check is the effective usage of both serological and molecular diagnostic testing. The article provides the readers with the basic understanding of the current pandemic situation and educates them regarding the same. It is essential that members of all the scientific background are aware of the current pandemic at its basic level. This would direct the scientific community to work toward warding off the pandemic which is the need of the hour.
最近爆发的严重急性呼吸系统综合征-冠状病毒2使人类的生存和存在降至历史最低点。这种感染似乎无法控制,科学界还没有答案。控制感染的唯一方法是有效使用血清学和分子诊断检测。这篇文章使读者对当前的疫情有了基本的了解,并进行了相应的教育。所有具有科学背景的成员都必须在基本层面上了解当前的大流行病。这将指导科学界为防止当前需要的大流行而努力。
{"title":"Diagnostically fighting the coronavirus disease 2019 pandemic: A general perspective","authors":"P. Ramesh, Brunda Arun, Devananda Devegowda","doi":"10.4103/ijhas.IJHAS_217_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_217_20","url":null,"abstract":"The recent outbreak of severe acute respiratory syndrome-coronavirus 2 has brought human survival and existence to an all-time low. The infection seems to be uncontrollable, and the scientific community has no answer yet. The only means of keeping the infection under the check is the effective usage of both serological and molecular diagnostic testing. The article provides the readers with the basic understanding of the current pandemic situation and educates them regarding the same. It is essential that members of all the scientific background are aware of the current pandemic at its basic level. This would direct the scientific community to work toward warding off the pandemic which is the need of the hour.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"35 1","pages":"108 - 114"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84386170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of the unanticipated difficult airway where bougie was used as a conduit over I gel as a rescue airway for one-lung ventilation under direct vision of fiberoptic bronchoscopy 在纤维支气管镜直视下,使用bougie作为I - gel上的导管作为单肺通气的救援气道
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_38_20
Shalendra Singh, Arijit Ray, D. Dwivedi, Saurabh Sud, Priya Taank
The basic foremost step for any surgery done under general anesthesia is to place an endotracheal tube (ETT) into the trachea. Placement of a definitive airway is vital to maintain a critical level of oxygen in the end organ during apnea time. There are multiple ways revealed in the literature to place ETT into the trachea. Sometimes, placement can be achieved speedily at the critical time with the experience of anesthesiologist and availability of different airway adjutants. Here, we describe a case of ETT intubation using bougie as a conduit over I gel under direct vision of fiberoptic bronchoscopy in a thymic enhancing mass.
在全身麻醉下进行任何手术的最基本的步骤是将气管内插管(ETT)插入气管。在呼吸暂停期间,最终气道的放置对于维持终末器官的临界氧气水平至关重要。文献中揭示了将ETT放入气管的多种方法。有时,在关键时刻,麻醉师的经验和不同气道辅助剂的可用性可以迅速实现放置。在这里,我们描述了一个在纤维支气管镜下直接观察胸腺增强肿块的ETT插管,使用bougie作为导管穿过I凝胶。
{"title":"A case of the unanticipated difficult airway where bougie was used as a conduit over I gel as a rescue airway for one-lung ventilation under direct vision of fiberoptic bronchoscopy","authors":"Shalendra Singh, Arijit Ray, D. Dwivedi, Saurabh Sud, Priya Taank","doi":"10.4103/ijhas.IJHAS_38_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_38_20","url":null,"abstract":"The basic foremost step for any surgery done under general anesthesia is to place an endotracheal tube (ETT) into the trachea. Placement of a definitive airway is vital to maintain a critical level of oxygen in the end organ during apnea time. There are multiple ways revealed in the literature to place ETT into the trachea. Sometimes, placement can be achieved speedily at the critical time with the experience of anesthesiologist and availability of different airway adjutants. Here, we describe a case of ETT intubation using bougie as a conduit over I gel under direct vision of fiberoptic bronchoscopy in a thymic enhancing mass.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"227 1","pages":"173 - 174"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76326296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is the panoramic radiography sufficient for detecting the relationship of the posterior maxillary teeth with maxillary sinus floor? A retrospective study comparative with cone-beam computed tomography 全景x线摄影是否足以检测上颌后牙与上颌窦底的关系?一项回顾性研究,比较锥束计算机断层扫描
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_281_20
F. Dogan, Bilgun Cetin, F. Akgünlü
BACKGROUND: The topographical description of the relationship between the upper posterior roots and the maxillary sinus is essential for decreasing the risk of complications during surgical or nonsurgical procedures and to detect possible sinus pathologies. For the evaluation, the most commonly used imaging method is panoramic radiography. This study aims to investigate the reliability of panoramic radiography according to cone-beam computed tomography (CBCT), which is extremely successful in the three-dimensional evaluation, by examining the relationship between the maxillary teeth and the sinus floor. MATERIALS AND METHODS: A total of 350 teeth were analyzed according to their topographic relationship to the maxillary sinus using panoramic and CBCT images. Two parameters were used to evaluate the safety of the panoramic radiograph on the posterior maxillary region. First, the topographic relationship was classified according to the criteria organized by Shahbazian et al. and compared both the imaging methods by the McNemar–Bowker test. Then, the diagnostic reliability test was performed for panoramic radiography according to the topographic classification. Second, 248 linear vertical measurements were made between the apexes of the roots and the sinus floor in the maxillary posterior region and then compared between the panoramic and the CBCT images. RESULTS: The McNemar–Bowker test showed that there was a significant relationship between the two imaging methods in both the dental groups (premolar teeth P = 0.030 and molar teeth P = 0.014). Furthermore, a total of 124 measurements were analyzed using the Mann–Whitney U-test and no statistically significant difference was found between the two imaging methods (P = 0.576). CONCLUSION: Although reliable results were obtained in panoramic radiographs when compared to CBCT images, panoramic radiography may not be sufficient before the surgical procedure. Nevertheless, when the posterior maxillary teeth are not too close to the sinus floor, panoramic radiographs can be used safely for the initial diagnostic evaluation.
背景:上颌后根与上颌窦之间的关系的地形描述对于降低手术或非手术过程中并发症的风险以及发现可能的鼻窦病变是必不可少的。对于评估,最常用的成像方法是全景x线摄影。本研究旨在通过检查上颌牙与窦底之间的关系,探讨在三维评估中非常成功的锥形束计算机断层扫描(CBCT)全景x线摄影的可靠性。材料与方法:采用全景和CBCT图像,根据上颌窦的地形关系对350颗牙齿进行分析。采用两个参数评价上颌后区全景x线片的安全性。首先,根据Shahbazian等人组织的标准对地形关系进行分类,并用McNemar-Bowker检验对两种成像方法进行比较。然后,根据地形分类对全景x线摄影进行诊断可靠性检验。其次,在上颌后区根尖与窦底之间进行248次直线垂直测量,并将全景图像与CBCT图像进行比较。结果:两牙组的McNemar-Bowker检验结果显示两种影像学检查方法之间存在显著相关性(前磨牙P = 0.030,磨牙P = 0.014)。此外,使用Mann-Whitney u检验对124个测量值进行分析,两种成像方法之间无统计学差异(P = 0.576)。结论:尽管与CBCT图像相比,全景x线片获得了可靠的结果,但在手术前全景x线片可能还不够。然而,当上颌后牙不太靠近窦底时,可以安全地使用全景x线片进行初步诊断评估。
{"title":"Is the panoramic radiography sufficient for detecting the relationship of the posterior maxillary teeth with maxillary sinus floor? A retrospective study comparative with cone-beam computed tomography","authors":"F. Dogan, Bilgun Cetin, F. Akgünlü","doi":"10.4103/ijhas.IJHAS_281_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_281_20","url":null,"abstract":"BACKGROUND: The topographical description of the relationship between the upper posterior roots and the maxillary sinus is essential for decreasing the risk of complications during surgical or nonsurgical procedures and to detect possible sinus pathologies. For the evaluation, the most commonly used imaging method is panoramic radiography. This study aims to investigate the reliability of panoramic radiography according to cone-beam computed tomography (CBCT), which is extremely successful in the three-dimensional evaluation, by examining the relationship between the maxillary teeth and the sinus floor. MATERIALS AND METHODS: A total of 350 teeth were analyzed according to their topographic relationship to the maxillary sinus using panoramic and CBCT images. Two parameters were used to evaluate the safety of the panoramic radiograph on the posterior maxillary region. First, the topographic relationship was classified according to the criteria organized by Shahbazian et al. and compared both the imaging methods by the McNemar–Bowker test. Then, the diagnostic reliability test was performed for panoramic radiography according to the topographic classification. Second, 248 linear vertical measurements were made between the apexes of the roots and the sinus floor in the maxillary posterior region and then compared between the panoramic and the CBCT images. RESULTS: The McNemar–Bowker test showed that there was a significant relationship between the two imaging methods in both the dental groups (premolar teeth P = 0.030 and molar teeth P = 0.014). Furthermore, a total of 124 measurements were analyzed using the Mann–Whitney U-test and no statistically significant difference was found between the two imaging methods (P = 0.576). CONCLUSION: Although reliable results were obtained in panoramic radiographs when compared to CBCT images, panoramic radiography may not be sufficient before the surgical procedure. Nevertheless, when the posterior maxillary teeth are not too close to the sinus floor, panoramic radiographs can be used safely for the initial diagnostic evaluation.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"1 1","pages":"123 - 128"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75990066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ensuring safe handling of the dead bodies of people succumbing to coronavirus disease-2019 infection 确保安全处理2019冠状病毒感染患者的尸体
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_224_20
S. Shrivastava, P. Shrivastava
The coronavirus disease-2019 (COVID-19) pandemic has resulted in the disruption of the lives of everyone, with marginalized and high-risk population groups being the most affected. As the transmission of the virus is predominantly through close contact or respiratory droplets or fomites, it becomes a careful consideration to carefully handle the bodies of the people who have lost their lives either as a suspected or as a confirmed case of the disease. As there is a definite possibility of the presence of the live virus in the organs of a patient who died when s/he was infectious, it becomes a mandatory requirement to ensure the provision of safety measures. In conclusion, it is of paramount importance to safely deal with the bodies of the people who have died due to COVID-19 infection. However, it becomes equally important to maintain the dignity of the dead and respect the cultural norms of the family as well as the community and at the same time taking adequate measures to ensure safety.
2019冠状病毒病(COVID-19)大流行扰乱了每个人的生活,边缘化和高危人群受到的影响最大。由于病毒的传播主要是通过密切接触或呼吸道飞沫或污染物,因此,无论是作为该病的疑似病例还是确诊病例,都必须谨慎处理死者的尸体。由于在感染时死亡的病人的器官中确实存在活病毒的可能性,因此确保提供安全措施成为强制性要求。总之,安全处理因COVID-19感染而死亡的人的尸体至关重要。然而,同样重要的是维护死者的尊严,尊重家庭和社区的文化规范,同时采取适当措施确保安全。
{"title":"Ensuring safe handling of the dead bodies of people succumbing to coronavirus disease-2019 infection","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/ijhas.IJHAS_224_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_224_20","url":null,"abstract":"The coronavirus disease-2019 (COVID-19) pandemic has resulted in the disruption of the lives of everyone, with marginalized and high-risk population groups being the most affected. As the transmission of the virus is predominantly through close contact or respiratory droplets or fomites, it becomes a careful consideration to carefully handle the bodies of the people who have lost their lives either as a suspected or as a confirmed case of the disease. As there is a definite possibility of the presence of the live virus in the organs of a patient who died when s/he was infectious, it becomes a mandatory requirement to ensure the provision of safety measures. In conclusion, it is of paramount importance to safely deal with the bodies of the people who have died due to COVID-19 infection. However, it becomes equally important to maintain the dignity of the dead and respect the cultural norms of the family as well as the community and at the same time taking adequate measures to ensure safety.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"14 1","pages":"167 - 168"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90007001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anesthetic management of a case of post tubercular unilateral total lung fibrosis undergoing laparoscopic cholecystectomy 腹腔镜胆囊切除术中单侧全肺纤维化1例的麻醉处理
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_219_20
A. Barik, Ashutosh Kaushal, Ajit Kumar, Jaharan Mohanta
{"title":"Anesthetic management of a case of post tubercular unilateral total lung fibrosis undergoing laparoscopic cholecystectomy","authors":"A. Barik, Ashutosh Kaushal, Ajit Kumar, Jaharan Mohanta","doi":"10.4103/ijhas.IJHAS_219_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_219_20","url":null,"abstract":"","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"11 1","pages":"180 - 182"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87695600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does higher consumption of white rice increase the risk of type 2 diabetes? 多吃白米会增加患2型糖尿病的风险吗?
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_245_20
C. Okechukwu
{"title":"Does higher consumption of white rice increase the risk of type 2 diabetes?","authors":"C. Okechukwu","doi":"10.4103/ijhas.IJHAS_245_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_245_20","url":null,"abstract":"","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"33 1","pages":"175 - 176"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87513347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relation between dermatoglyphic patterns and intelligence quotient and socioeconomic status in healthy children and children with intellectual disability: An observational study 健康儿童和智力残疾儿童皮肤纹型与智商和社会经济地位的关系:一项观察性研究
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_96_20
S. Nirmala, N. Tharay, S. Nuvvula
AIM: To measure the intelligence quotient (IQ) and documentation of dermatoglyphic patterns of normal and children with intellectually disability aged between the 5-11 years. MATERIALS AND METHODS: The present study was conducted in two schools and the Red Cross Society. A total of 100 children aged between 5-11 years equally owed into two groups based on IQ using adaptive covariate randomization. Ravens Progressive Color Matrices were used to measure IQ of the children, whereas IQ of intellectually disabled (ID) children was measured by the Seguin board; both the scales are nonverbal intelligence scales, respectively. Bilateral palmar and fingerprints were obtained on the bond paper by the ink method using the rolling technique. Prints thus purchased were analyzed for the dermatoglyphic variables using a magnification lens and are read based on Cummins and Midlo classification The children were also classified according to the socioeconomic status of their parents and whether any correlation exists between IQ and socioeconomic status exists was assessed. The analysis performed by using the crosstabs and Chi-square tests for fingertip patterns and creases. For ATD angle, (a, t, d Triradii Angle) t-test for the equality of means performed. For statistical significance, two-tailed probability values of <0.05 considered as significant. RESULTS: Among the children with below-average IQ and also the ID children difference in dermatoglyphic patterns exists in between digits I, II, IV, and V of the right hand and digits I, II, III, and V of the left side. CONCLUSION: Dermatoglyphics can consider as a preliminary noninvasive approach for the determination of IQ. Furthermore, it plays an imperative role, especially in distinguishing genetic intellectual disabilities. There was no association between socioeconomic status and IQ of children.
目的:测定5 ~ 11岁正常儿童和智力残疾儿童皮肤纹型的智商和文献资料。材料与方法:本研究在两所学校和红十字会进行。采用自适应协变量随机化方法,将100名年龄在5-11岁之间的儿童根据智商平均分为两组。采用Ravens渐进式颜色矩阵测量儿童智商,采用Seguin板测量智障儿童智商;这两个量表都是非语言智力量表。采用滚墨法在铜版纸上获得双侧掌纹和指纹。研究人员使用放大镜对购买的指纹进行了皮肤纹变量分析,并根据康明斯和米德洛分类进行了解读。研究人员还根据父母的社会经济地位对儿童进行了分类,并评估了智商与社会经济地位之间是否存在相关性。分析使用交叉表和卡方检验指尖图案和折痕。对于ATD角,(a, t, d Triradii角)进行均值相等性t检验。对于统计显著性,以双侧概率值<0.05为显著。结果:在智商低于平均水平的儿童和ID儿童中,右手数字I、II、IV、V和左手数字I、II、III、V之间的皮肤纹模式存在差异。结论:皮纹法可作为一种初步的无创测定IQ的方法。此外,它还发挥着至关重要的作用,特别是在区分遗传性智力残疾方面。儿童的社会经济地位和智商之间没有联系。
{"title":"Relation between dermatoglyphic patterns and intelligence quotient and socioeconomic status in healthy children and children with intellectual disability: An observational study","authors":"S. Nirmala, N. Tharay, S. Nuvvula","doi":"10.4103/ijhas.IJHAS_96_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_96_20","url":null,"abstract":"AIM: To measure the intelligence quotient (IQ) and documentation of dermatoglyphic patterns of normal and children with intellectually disability aged between the 5-11 years. MATERIALS AND METHODS: The present study was conducted in two schools and the Red Cross Society. A total of 100 children aged between 5-11 years equally owed into two groups based on IQ using adaptive covariate randomization. Ravens Progressive Color Matrices were used to measure IQ of the children, whereas IQ of intellectually disabled (ID) children was measured by the Seguin board; both the scales are nonverbal intelligence scales, respectively. Bilateral palmar and fingerprints were obtained on the bond paper by the ink method using the rolling technique. Prints thus purchased were analyzed for the dermatoglyphic variables using a magnification lens and are read based on Cummins and Midlo classification The children were also classified according to the socioeconomic status of their parents and whether any correlation exists between IQ and socioeconomic status exists was assessed. The analysis performed by using the crosstabs and Chi-square tests for fingertip patterns and creases. For ATD angle, (a, t, d Triradii Angle) t-test for the equality of means performed. For statistical significance, two-tailed probability values of <0.05 considered as significant. RESULTS: Among the children with below-average IQ and also the ID children difference in dermatoglyphic patterns exists in between digits I, II, IV, and V of the right hand and digits I, II, III, and V of the left side. CONCLUSION: Dermatoglyphics can consider as a preliminary noninvasive approach for the determination of IQ. Furthermore, it plays an imperative role, especially in distinguishing genetic intellectual disabilities. There was no association between socioeconomic status and IQ of children.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"16 1","pages":"129 - 133"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80579046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Key population of HIV should not be forgotten in Africa's COVID-19 response: Nigeria as a case study 非洲应对COVID-19不应忘记艾滋病毒关键人群:以尼日利亚为案例研究
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_257_20
Folami Balogun, Y. Adebisi, Pascal Akahome
{"title":"Key population of HIV should not be forgotten in Africa's COVID-19 response: Nigeria as a case study","authors":"Folami Balogun, Y. Adebisi, Pascal Akahome","doi":"10.4103/ijhas.IJHAS_257_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_257_20","url":null,"abstract":"","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"82 1","pages":"185 - 187"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85969977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kolaviron ameliorates toxic effects of aluminum chloride on the hippocampus of fetal Wistar rats in utero: Biochemical and ultrastructural observations 柯拉维铁可改善胎儿Wistar大鼠子宫内氯化铝对海马的毒性作用:生化和超微结构观察
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_117_20
S. Lewu, B. Enaibe
BACKGROUND: This study was designed to investigate the biochemical and ultrastructural effects of kolaviron (Kv) on the hippocampus of fetal Wistar rats exposed to aluminum chloride (AlCl3) toxicity in utero. MATERIALS AND METHODS: Fifty female Wistar rats were selected at random and mated. Following confirmation of mating, pregnant rats were assigned into five groups (n = 5). Controls: Group A received distilled water; Group B: 0.6 ml of corn oil; Group C: 200 mg/kg of Kv; Group D: 100 mg/kg of AlCl3 and Group E 100 mg/kg of AlCl3 and 200 mg/kg of Kv. Administration was done from days 8-10 and 15-17 of gestation during the 2nd and 3rd weeks respectively. Biochemical analyses were investigated to assess oxidative stress levels, while transmission electron microscopy (TEM) examined ultrastructural changes. Pregnant animals were sacrificed on day 20 of gestation; fetuses, their brains, and hippocampi were excised, respectively. Hippocampal tissues of fetuses were homogenized in 0.25 M of sucrose solution for biochemical assay while some were fixed in 2.5% phosphate-buffered saline-based glutaraldehyde for TEM. RESULTS: Elevated levels of Al, malondialdehyde, nitric oxide, and interleukin 6 were observed in the hippocampi of fetuses whose mothers received AlCl3. TEM revealed loss of nuclear membrane and increased condensation of chromatin materials in the same group. However, significant reduction of these enzymes including improved ultrastructural alterations were observed in the fetal hippocampus of the AlCl3 + Kv-treated group. CONCLUSION: This study showed that Kv significantly reduced neurodegenerative effects induced by AlCl3 in the hippocampii of fetal Wistar rats in utero probably owing to its antioxidant and anti-inflammatory properties.
背景:本研究旨在探讨柯拉维铁(Kv)对子宫内暴露于氯化铝(AlCl3)毒性的胎鼠海马的生化和超微结构的影响。材料与方法:随机选取雌性Wistar大鼠50只,进行交配。确定交配后,将怀孕大鼠分为5组(n = 5)。对照组:A组给予蒸馏水;B组:玉米油0.6 ml;C组:200mg /kg Kv;D组:AlCl3 100mg /kg, E组:AlCl3 100mg /kg, Kv 200mg /kg。分别于妊娠第2周和第3周第8-10天和第15-17天给药。通过生化分析评估氧化应激水平,透射电镜(TEM)检查超微结构变化。孕鼠于妊娠第20天处死;分别切除胎儿、他们的大脑和海马体。将胎儿海马组织匀浆于0.25 M蔗糖溶液中进行生化分析,部分组织固定于2.5%磷酸盐缓冲盐基戊二醛中进行透射电镜观察。结果:母亲接受AlCl3治疗的胎儿海马中Al、丙二醛、一氧化氮和白细胞介素6水平升高。透射电镜显示核膜的丢失和染色质物质的凝结增加。然而,在AlCl3 + kv处理组的胎儿海马中,观察到这些酶的显著减少,包括超微结构改变的改善。结论:本研究表明,Kv可能与其抗氧化和抗炎作用有关,可显著降低胎儿Wistar大鼠子宫内AlCl3诱导的海马神经退行性作用。
{"title":"Kolaviron ameliorates toxic effects of aluminum chloride on the hippocampus of fetal Wistar rats in utero: Biochemical and ultrastructural observations","authors":"S. Lewu, B. Enaibe","doi":"10.4103/ijhas.IJHAS_117_20","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_117_20","url":null,"abstract":"BACKGROUND: This study was designed to investigate the biochemical and ultrastructural effects of kolaviron (Kv) on the hippocampus of fetal Wistar rats exposed to aluminum chloride (AlCl3) toxicity in utero. MATERIALS AND METHODS: Fifty female Wistar rats were selected at random and mated. Following confirmation of mating, pregnant rats were assigned into five groups (n = 5). Controls: Group A received distilled water; Group B: 0.6 ml of corn oil; Group C: 200 mg/kg of Kv; Group D: 100 mg/kg of AlCl3 and Group E 100 mg/kg of AlCl3 and 200 mg/kg of Kv. Administration was done from days 8-10 and 15-17 of gestation during the 2nd and 3rd weeks respectively. Biochemical analyses were investigated to assess oxidative stress levels, while transmission electron microscopy (TEM) examined ultrastructural changes. Pregnant animals were sacrificed on day 20 of gestation; fetuses, their brains, and hippocampi were excised, respectively. Hippocampal tissues of fetuses were homogenized in 0.25 M of sucrose solution for biochemical assay while some were fixed in 2.5% phosphate-buffered saline-based glutaraldehyde for TEM. RESULTS: Elevated levels of Al, malondialdehyde, nitric oxide, and interleukin 6 were observed in the hippocampi of fetuses whose mothers received AlCl3. TEM revealed loss of nuclear membrane and increased condensation of chromatin materials in the same group. However, significant reduction of these enzymes including improved ultrastructural alterations were observed in the fetal hippocampus of the AlCl3 + Kv-treated group. CONCLUSION: This study showed that Kv significantly reduced neurodegenerative effects induced by AlCl3 in the hippocampii of fetal Wistar rats in utero probably owing to its antioxidant and anti-inflammatory properties.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"1 1","pages":"115 - 122"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89894541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cervical spine range of motion and joint position sense in elite male cricketers: An observational study 优秀男子板球运动员颈椎活动度和关节位置感:一项观察性研究
Pub Date : 2021-04-01 DOI: 10.4103/ijhas.IJHAS_111_19
S. Reid, Johnathan Fornasier, D. Redrup, S. McLeod
OBJECTIVE: The aims of the current study were to (1) establish baseline data for cervical range of motion (CROM) and joint position sense (JPS) in elite male cricketers, (2) determine whether these players had differences when compared to healthy adults, and (3) establish a reference set of values for future investigations. MATERIALS AND METHODS: Design: Repeated measures, observational study. Participants: Thirty-one elite cricketers, aged 18–35 years. Setting: Cricket New South Wales at the Sydney Cricket Ground, Sydney, Australia. Outcome measures: Cervical rotation was measured with a CROM device and JPS using the joint position error (JPE) laser method with two protocols: repositioning to straight ahead and to 80% of maximum rotation. RESULTS: Mean right and left rotation were less than healthy normals by 6.5° (P < 0.001) and 4.2° (P < 0.001), respectively. In the preseason, 26% of cricketers had JPE >4.5° repositioning to straight ahead, which is 11% greater than the general population and 87% had JPE >4.5° when repositioning to 80% rotation. Postseason, deficits in CROM were unchanged. Fewer players (22%) had JPE >4.5° when repositioning to straight ahead however JPE when repositioning to 80% of rotation increased 1° for both directions (P < 0.05). CONCLUSIONS: Contrary to the authors' hypothesis, preliminary findings from this study demonstrated that elite male cricketers in this cohort had deficits in CROM and JPS, compared to normal healthy adults. This has clinical implications for the use of physical therapies targeting JPS and restoring CROM pre- and post-head and neck injury. Therapists should account for preexisting, baseline asymmetries in the range of motion and JPE in male cricketers. Further research needs to validate these findings across adolescent and female cricketers and explore the interaction between cervical spine parameters, cricket biomechanics, and head or neck injury risk.
目的:本研究的目的是(1)建立优秀男子板球运动员颈椎活动度(CROM)和关节位置感(JPS)的基线数据,(2)确定这些运动员与健康成年人相比是否存在差异,(3)为未来的研究建立一套参考值。材料与方法:设计:重复测量,观察性研究。参与者:31名优秀板球运动员,年龄18-35岁。背景:澳大利亚悉尼悉尼板球场的新南威尔士板球赛。结果测量:使用CROM装置和JPS使用关节位置误差(JPE)激光方法测量颈椎旋转,有两种方案:重新定位到正前方和最大旋转的80%。结果:平均右转和左转分别比健康正常人少6.5°(P < 0.001)和4.2°(P < 0.001)。在季前赛中,26%的板球运动员的JPE >4.5°,比一般人群高11%,87%的板球运动员的JPE >4.5°。季后赛,CROM的赤字没有变化。更少的球员(22%)在重新定位到正前方时JPE >4.5°,而当重新定位到旋转的80%时,JPE在两个方向上都增加了1°(P < 0.05)。结论:与作者的假设相反,本研究的初步结果表明,与正常健康成人相比,该队列中的优秀男性板球运动员在CROM和JPS方面存在缺陷。这对于使用针对JPS的物理治疗和恢复CROM前后头颈部损伤具有临床意义。治疗师应该考虑到男性板球运动员先前存在的运动范围和JPE的基线不对称。进一步的研究需要在青少年和女性板球运动员中验证这些发现,并探索颈椎参数、板球生物力学和头颈部损伤风险之间的相互作用。
{"title":"Cervical spine range of motion and joint position sense in elite male cricketers: An observational study","authors":"S. Reid, Johnathan Fornasier, D. Redrup, S. McLeod","doi":"10.4103/ijhas.IJHAS_111_19","DOIUrl":"https://doi.org/10.4103/ijhas.IJHAS_111_19","url":null,"abstract":"OBJECTIVE: The aims of the current study were to (1) establish baseline data for cervical range of motion (CROM) and joint position sense (JPS) in elite male cricketers, (2) determine whether these players had differences when compared to healthy adults, and (3) establish a reference set of values for future investigations. MATERIALS AND METHODS: Design: Repeated measures, observational study. Participants: Thirty-one elite cricketers, aged 18–35 years. Setting: Cricket New South Wales at the Sydney Cricket Ground, Sydney, Australia. Outcome measures: Cervical rotation was measured with a CROM device and JPS using the joint position error (JPE) laser method with two protocols: repositioning to straight ahead and to 80% of maximum rotation. RESULTS: Mean right and left rotation were less than healthy normals by 6.5° (P < 0.001) and 4.2° (P < 0.001), respectively. In the preseason, 26% of cricketers had JPE >4.5° repositioning to straight ahead, which is 11% greater than the general population and 87% had JPE >4.5° when repositioning to 80% rotation. Postseason, deficits in CROM were unchanged. Fewer players (22%) had JPE >4.5° when repositioning to straight ahead however JPE when repositioning to 80% of rotation increased 1° for both directions (P < 0.05). CONCLUSIONS: Contrary to the authors' hypothesis, preliminary findings from this study demonstrated that elite male cricketers in this cohort had deficits in CROM and JPS, compared to normal healthy adults. This has clinical implications for the use of physical therapies targeting JPS and restoring CROM pre- and post-head and neck injury. Therapists should account for preexisting, baseline asymmetries in the range of motion and JPE in male cricketers. Further research needs to validate these findings across adolescent and female cricketers and explore the interaction between cervical spine parameters, cricket biomechanics, and head or neck injury risk.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"20 1","pages":"134 - 140"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85776573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Health and Allied Sciences
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1