A Garzi, U Ferrentino, G Ardimento, S Brongo, M S Rubino, E Calabrò, E Clemente, R M Di Crescenzo
Congenital cystic adenomatoid malformation (CCAM) is a rare congenital lung lesion. It may appear since birth (30-35%) with difficulty breathing or may have a late onset (60-65%) with recurring pulmonary infections or growth failure; in a small percentage of cases, the lesion can be completely asymptomatic. Fetal or post-natal surgery can be used as surgical treatment of these lesions. Postnatal surgery consists of a lobectomy, bilobectomy or pneumonectomy, based on the size of the lesion. The best age to undergo this surgery is around 2 years, but only if the injury is stable and the child has no complications. The study describes three cases of CCAM, observed at the Pediatric Surgery Section of the University of Siena. We analyzed those 3 cases whose approach was defined by the onset of symptoms, age and clinical condition of patients. In the first case the surgery was performed a few hours after birth due to the worsening of the clinical conditions; in the other two cases it was delayed because the patients were asymptomatic. The purpose of this study is to review the management of patients with CCAM in relation to clinical onset and the type of injury.
{"title":"Congenital Cystic Adenomatoid Malformation of the Lung Tipe II: Three Cases Report.","authors":"A Garzi, U Ferrentino, G Ardimento, S Brongo, M S Rubino, E Calabrò, E Clemente, R M Di Crescenzo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Congenital cystic adenomatoid malformation (CCAM) is a rare congenital lung lesion. It may appear since birth (30-35%) with difficulty breathing or may have a late onset (60-65%) with recurring pulmonary infections or growth failure; in a small percentage of cases, the lesion can be completely asymptomatic. Fetal or post-natal surgery can be used as surgical treatment of these lesions. Postnatal surgery consists of a lobectomy, bilobectomy or pneumonectomy, based on the size of the lesion. The best age to undergo this surgery is around 2 years, but only if the injury is stable and the child has no complications. The study describes three cases of CCAM, observed at the Pediatric Surgery Section of the University of Siena. We analyzed those 3 cases whose approach was defined by the onset of symptoms, age and clinical condition of patients. In the first case the surgery was performed a few hours after birth due to the worsening of the clinical conditions; in the other two cases it was delayed because the patients were asymptomatic. The purpose of this study is to review the management of patients with CCAM in relation to clinical onset and the type of injury.</p>","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"20 ","pages":"4-8"},"PeriodicalIF":1.5,"publicationDate":"2019-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37468779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Apóstolo, E Bobrowicz-Campos, I Gil, R Silva, P Costa, F Couto, D Cardoso, A Barata, M Almeida
The project Cognitive Stimulation in Older Adults: Intervention on Cognitive Frailty and Promotion of Self-Care (in brief the ECOG project) arises in a context of worldwide demographic aging, and is fostered by the need to provide a sustainable solution to the progressive increase in the prevalence of age-related cognitive impairment. The main goal of the ECOG project is to promote active citizenship in old age through the empowerment for autonomy and self-care. Namely, the ECOG team is working on the development of evidence-based programs and tools that promote gains in health in cognitively frail and cognitively impaired older adults from the community. It is also working on the transfer of ECOG products to the practice of health and social care, promoting active involvement of geriatric care institutions in the implementation of the ECOG programs and tools, and ensuring appropriate training of professionals. Finally, the ECOG team is deploying a digital platform to reach out to the broadest audience possible and support the remote access and scaling up of the ECOG products. The impacts expected at an individual level include improvements in cognition, functionality, and autonomy of older adults, with simultaneous reduction of depressive symptomatology, and increase in quality of life of both person cared and his/her caregiver. Regarding societal gains, we anticipate an increase in life expectancy and significant postponement of institutionalization associated with geriatric problems. We also believe that the wide implementation of the ECOG products will reduce the costs of interventions for cognitively impaired citizens, contributing to sustainability and efficiency of health systems.
{"title":"Cognitive Stimulation in Older Adults: An Innovative Good Practice Supporting Successful Aging and Self-Care.","authors":"J Apóstolo, E Bobrowicz-Campos, I Gil, R Silva, P Costa, F Couto, D Cardoso, A Barata, M Almeida","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The project Cognitive Stimulation in Older Adults: Intervention on Cognitive Frailty and Promotion of Self-Care (in brief the ECOG project) arises in a context of worldwide demographic aging, and is fostered by the need to provide a sustainable solution to the progressive increase in the prevalence of age-related cognitive impairment. The main goal of the ECOG project is to promote active citizenship in old age through the empowerment for autonomy and self-care. Namely, the ECOG team is working on the development of evidence-based programs and tools that promote gains in health in cognitively frail and cognitively impaired older adults from the community. It is also working on the transfer of ECOG products to the practice of health and social care, promoting active involvement of geriatric care institutions in the implementation of the ECOG programs and tools, and ensuring appropriate training of professionals. Finally, the ECOG team is deploying a digital platform to reach out to the broadest audience possible and support the remote access and scaling up of the ECOG products. The impacts expected at an individual level include improvements in cognition, functionality, and autonomy of older adults, with simultaneous reduction of depressive symptomatology, and increase in quality of life of both person cared and his/her caregiver. Regarding societal gains, we anticipate an increase in life expectancy and significant postponement of institutionalization associated with geriatric problems. We also believe that the wide implementation of the ECOG products will reduce the costs of interventions for cognitively impaired citizens, contributing to sustainability and efficiency of health systems.</p>","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 ","pages":"90-94"},"PeriodicalIF":1.1,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141749754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mauro Cataldi, V. D. Luca, G. Tramontano, C. D. Giudice, I. Grimaldi, P. Cuccaro, P. Speranza, G. Iadicicco, V. Iadicicco, F. Carotenuto, P. A. Riccio, G. D. Spigna, A. Renzullo, L. Vuolo, L. Barrea, S. Savastano, Annamaria Colao, Giuseppe Liotta, G. Iaccarino, Pasquale Abete, P. Buono, Miriam Marie Rosé Vollenbroek-Hutten, M. Illario
We developed and tested an innovative physical training method in older adults that embeds the gym program into everyday life in the most conservative way possible. Physical training was included in the activities of local parishes where older women from Southern Italy spend most of their free time and was delivered by trained physical therapists with the support of an ICT tool known as CoCo. 113 older women (aged 72.0 [69.0–75.0] years) noncompliant to conventional exercise programs participated to the study. 57 of them underwent the final anthropometric assessment and 50 the final physical tests. In study completers handgrip strength and physical performance evaluated with the chair-stand, the two minutes step and the chair-sit and -reach tests significantly improved. Quality of life as evaluated with the EuroQol-5dimension (EQ-5D) questionnaire improved as well. In conclusion, a training program designed to minimally impact on life habits of older people is effective in improving fitness in patients noncompliant to other to physical exercise programs.
{"title":"An Approach to Prevent Frailty in Community Dwelling Older Adults: a pilot study performed in Campania region in the framework of the PERSSILAA project","authors":"Mauro Cataldi, V. D. Luca, G. Tramontano, C. D. Giudice, I. Grimaldi, P. Cuccaro, P. Speranza, G. Iadicicco, V. Iadicicco, F. Carotenuto, P. A. Riccio, G. D. Spigna, A. Renzullo, L. Vuolo, L. Barrea, S. Savastano, Annamaria Colao, Giuseppe Liotta, G. Iaccarino, Pasquale Abete, P. Buono, Miriam Marie Rosé Vollenbroek-Hutten, M. Illario","doi":"10.14273/UNISA-2725","DOIUrl":"https://doi.org/10.14273/UNISA-2725","url":null,"abstract":"We developed and tested an innovative physical training method in older adults that embeds the gym program into everyday life in the most conservative way possible. Physical training was included in the activities of local parishes where older women from Southern Italy spend most of their free time and was delivered by trained physical therapists with the support of an ICT tool known as CoCo. 113 older women (aged 72.0 [69.0–75.0] years) noncompliant to conventional exercise programs participated to the study. 57 of them underwent the final anthropometric assessment and 50 the final physical tests. In study completers handgrip strength and physical performance evaluated with the chair-stand, the two minutes step and the chair-sit and -reach tests significantly improved. Quality of life as evaluated with the EuroQol-5dimension (EQ-5D) questionnaire improved as well. In conclusion, a training program designed to minimally impact on life habits of older people is effective in improving fitness in patients noncompliant to other to physical exercise programs.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 1","pages":"42 - 48"},"PeriodicalIF":1.5,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45726963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Bousquet, M. Illario, J. Farrell, N. Batey, A. Carriazo, J. Malva, J. Hajjam, E. Colgan, Nick A. Guldemond, M. Perälä-Heape, G. Onorato, A. Bedbrook, L. Leonardini, V. Stroetman, S. Birov, C. Abreu, A. Abrunhosa, A. Agrimi, T. Alalääkkölä, N. Allegretti, F. Alonso-Trujillo, M. Alvarez-Benito, S. Angioli, Joao Apostolo, G. Armitage, S. Arnavielhe, M. Baena-ParejoI, P. D. Bamidis, A. Balenović, M. Barbolini, I. Baroni, H. Blain, P. L. Bernard, M. Bersani, E. Berti, L. Bogatyrchuk, R. Bourret, J. Brehm, L. Brussino, D. Buhr, D. Bultje, E. Cabeza, Antonio Cano, C. Capitani, E. Carantoña, Ana F. Cardoso, J. I. C. Clavero, B. Combe, D. Conforti, Liliana Coppola, F. Corti, Enrico Coscioni, Elísio Costa, G. Crooks, António Cunha, C. Daien, Dantas, J. D. Sierra, M. Davoli, A. D. Baraldes, V. D. Luca, L. D. Nardi, M. D. Ciano, A. Dozet, B. Ekinci, S. Ervé, J. M. E. Almendro, A. Fait, R. Fensli, S. F. Nocelo, P. Galvez-Daza, J. Gámez-Payá, M. G. Sáez, I. G. Sanchez, B. Gemicioğlu, W. Goetzke, E. Goossens, M. Geur
Seventy four Reference Sites of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) have been recognised by the European Commission in 2016 for their commitment to excellence in investing and scaling up innovative solutions for active and healthy ageing. The Reference Site Collaborative Network (RSCN) brings together the EIP on AHA Reference Sites awarded by the European Commission, and Candidate Reference Sites into a single forum. The overarching goals are to promote cooperation, share and transfer good practice and solutions in the development and scaling up of health and care strategies, policies and service delivery models, while at the same time supporting the action groups in their work. The RSCN aspires to be recognized by the EU Commission as the principal forum and authority representing all EIP on AHA Reference Sites. The RSCN will contribute to achieve the goals of the EIP on AHA by improving health and care outcomes for citizens across Europe, and the development of sustainable economic growth and the creation of jobs.
2016年，欧洲积极健康老龄化创新伙伴关系(EIP on AHA)的74个参考站点因致力于为积极健康老龄化投资和扩大创新解决方案而获得欧盟委员会的认可。参考站点协作网络(RSCN)将欧洲委员会授予的AHA参考站点的EIP和候选参考站点汇集到一个单一的论坛中。总体目标是在制定和扩大保健战略、政策和服务提供模式方面促进合作、分享和转让良好做法和解决办法，同时支持各行动小组的工作。RSCN希望得到欧盟委员会的认可，成为代表AHA参考网站上所有EIP的主要论坛和权威机构。RSCN将通过改善全欧洲公民的保健和护理成果，以及发展可持续的经济增长和创造就业机会，为实现《欧洲健康和保健知识规划》关于AHA的目标作出贡献。
{"title":"The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing","authors":"J. Bousquet, M. Illario, J. Farrell, N. Batey, A. Carriazo, J. Malva, J. Hajjam, E. Colgan, Nick A. Guldemond, M. Perälä-Heape, G. Onorato, A. Bedbrook, L. Leonardini, V. Stroetman, S. Birov, C. Abreu, A. Abrunhosa, A. Agrimi, T. Alalääkkölä, N. Allegretti, F. Alonso-Trujillo, M. Alvarez-Benito, S. Angioli, Joao Apostolo, G. Armitage, S. Arnavielhe, M. Baena-ParejoI, P. D. Bamidis, A. Balenović, M. Barbolini, I. Baroni, H. Blain, P. L. Bernard, M. Bersani, E. Berti, L. Bogatyrchuk, R. Bourret, J. Brehm, L. Brussino, D. Buhr, D. Bultje, E. Cabeza, Antonio Cano, C. Capitani, E. Carantoña, Ana F. Cardoso, J. I. C. Clavero, B. Combe, D. Conforti, Liliana Coppola, F. Corti, Enrico Coscioni, Elísio Costa, G. Crooks, António Cunha, C. Daien, Dantas, J. D. Sierra, M. Davoli, A. D. Baraldes, V. D. Luca, L. D. Nardi, M. D. Ciano, A. Dozet, B. Ekinci, S. Ervé, J. M. E. Almendro, A. Fait, R. Fensli, S. F. Nocelo, P. Galvez-Daza, J. Gámez-Payá, M. G. Sáez, I. G. Sanchez, B. Gemicioğlu, W. Goetzke, E. Goossens, M. Geur","doi":"10.14273/UNISA-2721","DOIUrl":"https://doi.org/10.14273/UNISA-2721","url":null,"abstract":"Seventy four Reference Sites of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) have been recognised by the European Commission in 2016 for their commitment to excellence in investing and scaling up innovative solutions for active and healthy ageing. The Reference Site Collaborative Network (RSCN) brings together the EIP on AHA Reference Sites awarded by the European Commission, and Candidate Reference Sites into a single forum. The overarching goals are to promote cooperation, share and transfer good practice and solutions in the development and scaling up of health and care strategies, policies and service delivery models, while at the same time supporting the action groups in their work. The RSCN aspires to be recognized by the EU Commission as the principal forum and authority representing all EIP on AHA Reference Sites. The RSCN will contribute to achieve the goals of the EIP on AHA by improving health and care outcomes for citizens across Europe, and the development of sustainable economic growth and the creation of jobs.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 1","pages":"66 - 81"},"PeriodicalIF":1.5,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46653888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. M. D. Santos, R. O’Caoimh, A. Svendrovski, C. Casanovas, F. Pernas, M. Illario, W. Molloy, Constança Paúl
As populations age and the prevalence of cognitive impairment increases, healthcare professionals and researchers require short, validated cognitive screening instruments (CSIs). As part the EIP-on-AHA Twinning Support Scheme (2016), four reference sites developed the RAPid COmmunity COGnitive screening Programme (RAPCOG) twinning project to validate translated versions of the Quick Mild Cognitive Impairment (Qmci) screen that could be adapted quickly for use with future eHealth screening and assessment programmes. Here we present the cultural adaption and translation of the Qmci-Portuguese (Qmci-P) screen as part of RAPCOG and explore its subsequent validation against two commonly-used CSIs (MMSE-P and MoCA-P) with 93 participants aged ≥65, attending ten day care centres or resident in two long-term care institutions; median age 74 (+/−15), 66% female. The Qmci-P’s internal consistency was high (Cronbach’s Alpha 0.82), compared with the MoCA (0.79) and SMMSE (0.54). Qmci-P screen scores moderately correlated with the SMMSE (r=0.61, 95% CI:0.45–0.72, p<0.001) and MoCA (r=0.63, 95% CI:0.36–0.80, p<0.001). The Qmci-P screen demonstrates high internal consistency and concurrent validity against more established CSIs and given its brevity (3–5mins), may be preferable for use in community settings. This project shows the potential of the EIP-on-AHA Twinning initiative to promote the scaling-up of innovative good practices.
{"title":"The RAPid COmmunity COGnitive screening Programme (RAPCOG): Developing the Portuguese version of the Quick Mild Cognitive Impairment (Qmci-P) screen as part of the EIP on AHA Twinning Scheme","authors":"P. M. D. Santos, R. O’Caoimh, A. Svendrovski, C. Casanovas, F. Pernas, M. Illario, W. Molloy, Constança Paúl","doi":"10.14273/UNISA-2720","DOIUrl":"https://doi.org/10.14273/UNISA-2720","url":null,"abstract":"As populations age and the prevalence of cognitive impairment increases, healthcare professionals and researchers require short, validated cognitive screening instruments (CSIs). As part the EIP-on-AHA Twinning Support Scheme (2016), four reference sites developed the RAPid COmmunity COGnitive screening Programme (RAPCOG) twinning project to validate translated versions of the Quick Mild Cognitive Impairment (Qmci) screen that could be adapted quickly for use with future eHealth screening and assessment programmes. Here we present the cultural adaption and translation of the Qmci-Portuguese (Qmci-P) screen as part of RAPCOG and explore its subsequent validation against two commonly-used CSIs (MMSE-P and MoCA-P) with 93 participants aged ≥65, attending ten day care centres or resident in two long-term care institutions; median age 74 (+/−15), 66% female. The Qmci-P’s internal consistency was high (Cronbach’s Alpha 0.82), compared with the MoCA (0.79) and SMMSE (0.54). Qmci-P screen scores moderately correlated with the SMMSE (r=0.61, 95% CI:0.45–0.72, p<0.001) and MoCA (r=0.63, 95% CI:0.36–0.80, p<0.001). The Qmci-P screen demonstrates high internal consistency and concurrent validity against more established CSIs and given its brevity (3–5mins), may be preferable for use in community settings. This project shows the potential of the EIP-on-AHA Twinning initiative to promote the scaling-up of innovative good practices.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 1","pages":"82 - 89"},"PeriodicalIF":1.5,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41465329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Peluso, D. Turchino, A. Petrone, A. Giribono, R. Bracale, L. del Guercio, U. Bracale
Carotid artery endarterectomy (CEA) is considered the gold standard for treatment of symptomatic and asymptomatic carotid disease. Carotid artery stenting (CAS) is a less invasive approach and therefore could be considered a viable alternative to CEA, especially in high-risk patients or those with relative contraindications to CEA (i.e. actinic stenosis, post-CEA restenosis, previous neck or tracheostomy surgery, contralateral laryngeal nerve paralysis, etc.). Methods The aim of this study is to evaluate the short- and medium-term outcomes of CAS performed with a single type of closed-cell stent design and distal filter protection by comparing the procedure with CEA based upon 3 endpoints: overall survival rate, stroke free survival rate and restenosis free survival rate. The same endpoints were also evaluated in 2 different age groups, more and less than 70 years, to show possible age-based differences on outcomes. Among 105 patients (77 males, 28 females), 74 were submitted to CEA and 31 were subject to CAS. In all cases the same self-expanding stent with closed-cell design (XACT Carotid Stent, Abbott Vascular) and the same distal embolic protection device (Emboshield NAV, Abbott Vascular) were employed. Results At 12 months, no statistically significant difference was observed in overall survival rates (CEA 93.2% vs CAS 93.5%, p=0.967) and restenosis free survival rates (CEA 94.5% vs CAS 96.8%, p=0.662). An increased stroke free survival rate was observed in the CEA group when compared to the CAS group (CEA 100.0% vs CAS 93.5%, p=0.028). The age-based endpoints didn’t show any significant difference. Conclusion These results suggest that CEA still remains the gold standard of treatment for carotid stenosis given its greater efficacy in the prevention of stroke CAS. However, CAS could be considered as an alternative treatment to CEA to be used in select cases only.
颈动脉内膜切除术（CEA）被认为是治疗有症状和无症状颈动脉疾病的金标准。颈动脉支架术（CAS）是一种侵入性较小的方法，因此可以被认为是CEA的可行替代方案，特别是高风险患者或对CEA有相对禁忌症的患者（如光化狭窄、CEA后再狭窄、既往颈部或气管切开术、对侧喉神经麻痹等）基于3个终点：总生存率、无卒中生存率和无再狭窄生存率将该手术与CEA进行比较。同样的终点也在两个不同的年龄组（70岁以上和70岁以下）中进行了评估，以显示可能基于年龄的结果差异。105名患者（77名男性，28名女性）中，74名接受了CEA，31名接受了CAS。在所有病例中，均使用相同的封闭细胞设计自膨胀支架（XACT颈动脉支架，Abbott Vascular）和相同的远端栓塞保护装置（Emboshield NAV，Abbott Vescular）。结果12个月时，总生存率（CEA 93.2%vs CAS 93.5%，p=0.967）和无再狭窄生存率（CEA94.5%vs CAS 96.8%，p=0.662）无统计学显著差异。与CAS组相比，CEA组无卒中生存率增加（CEA100.0%vs CAS 93.5%，p=0.028）。基于年龄的终点没有显示任何显著差异。结论CEA在预防脑卒中CAS中具有较高的疗效，仍是颈动脉狭窄治疗的金标准。然而，CAS可被视为CEA的替代治疗方法，仅用于部分病例。
{"title":"Standard Carotid Endarterectomy versus Carotid Artery Stenting with Closed-Cell Stent Design and Distal Embolic Protection: does the age matter?","authors":"A. Peluso, D. Turchino, A. Petrone, A. Giribono, R. Bracale, L. del Guercio, U. Bracale","doi":"10.14273/UNISA-2722","DOIUrl":"https://doi.org/10.14273/UNISA-2722","url":null,"abstract":"Carotid artery endarterectomy (CEA) is considered the gold standard for treatment of symptomatic and asymptomatic carotid disease. Carotid artery stenting (CAS) is a less invasive approach and therefore could be considered a viable alternative to CEA, especially in high-risk patients or those with relative contraindications to CEA (i.e. actinic stenosis, post-CEA restenosis, previous neck or tracheostomy surgery, contralateral laryngeal nerve paralysis, etc.). Methods The aim of this study is to evaluate the short- and medium-term outcomes of CAS performed with a single type of closed-cell stent design and distal filter protection by comparing the procedure with CEA based upon 3 endpoints: overall survival rate, stroke free survival rate and restenosis free survival rate. The same endpoints were also evaluated in 2 different age groups, more and less than 70 years, to show possible age-based differences on outcomes. Among 105 patients (77 males, 28 females), 74 were submitted to CEA and 31 were subject to CAS. In all cases the same self-expanding stent with closed-cell design (XACT Carotid Stent, Abbott Vascular) and the same distal embolic protection device (Emboshield NAV, Abbott Vascular) were employed. Results At 12 months, no statistically significant difference was observed in overall survival rates (CEA 93.2% vs CAS 93.5%, p=0.967) and restenosis free survival rates (CEA 94.5% vs CAS 96.8%, p=0.662). An increased stroke free survival rate was observed in the CEA group when compared to the CAS group (CEA 100.0% vs CAS 93.5%, p=0.028). The age-based endpoints didn’t show any significant difference. Conclusion These results suggest that CEA still remains the gold standard of treatment for carotid stenosis given its greater efficacy in the prevention of stroke CAS. However, CAS could be considered as an alternative treatment to CEA to be used in select cases only.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 1","pages":"60 - 65"},"PeriodicalIF":1.5,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42276369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Dantas, W van Staalduinen, A Jegundo, J Ganzarain, M Van der Mark, F Rodrigues, M Illario, V De Luca
The European Commission (DG SANTE) launched a call for proposals in November 2017 on strategic initiatives for a Joint Statement in 2018. Ten proposals were voted until December 7th in the European Union Health Policy Platform[1]; the proposal under the theme Smart Healthy Age-Friendly Environments (SHAFE)[2] was the most voted and was confirmed by the European Commission in March 2018. In this context, since March 2018, Cáritas Coimbra and AFEdemy Ltd are thus coordinating one of the three Thematic Networks for 2018, SHAFE, in close cooperation with main partners, such as the European Innovation Partnership on Active and Healthy Ageing (EIP-AHA), the European Innovation Partnership on Smart Cities and Communities (EIP-SCC), the Reference Sites Collaborative Network, the European Covenant on Demographic Change, Eurocities, the European Health Telematics Association (EHTEL), the European Connected Health Alliance (ECHAlliance), the European Construction, Built Environment and Energy Efficient Building Technology Platform (ECTP) and the European Centre for Social Welfare Policy and Research. SHAFE aims to facilitate the creation of healthy and friendly environments for all ages through the use of new technologies, towards the production of a comprehensive and participatory Joint Statement. This document was presented to the European Commission on 12 November 2018, with five main areas of recommendations to the EC, Member States and other local, regional and national organisations and is open for endorsement and implementation from this date onwards.
{"title":"Smart Healthy Age-Friendly Environments - Policy Recommendations of the Thematic Network <i>SHAFE</i>.","authors":"C Dantas, W van Staalduinen, A Jegundo, J Ganzarain, M Van der Mark, F Rodrigues, M Illario, V De Luca","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The European Commission (DG SANTE) launched a call for proposals in November 2017 on strategic initiatives for a Joint Statement in 2018. Ten proposals were voted until December 7th in the European Union Health Policy Platform[1]; the proposal under the theme <i>Smart Healthy Age-Friendly Environments</i> (SHAFE)[2] was the most voted and was confirmed by the European Commission in March 2018. In this context, since March 2018, Cáritas Coimbra and AFEdemy Ltd are thus coordinating one of the three Thematic Networks for 2018, SHAFE, in close cooperation with main partners, such as the European Innovation Partnership on Active and Healthy Ageing (EIP-AHA), the European Innovation Partnership on Smart Cities and Communities (EIP-SCC), the Reference Sites Collaborative Network, the European Covenant on Demographic Change, Eurocities, the European Health Telematics Association (EHTEL), the European Connected Health Alliance (ECHAlliance), the European Construction, Built Environment and Energy Efficient Building Technology Platform (ECTP) and the European Centre for Social Welfare Policy and Research. SHAFE aims to facilitate the creation of healthy and friendly environments for all ages through the use of new technologies, towards the production of a comprehensive and participatory Joint Statement. This document was presented to the European Commission on 12 November 2018, with five main areas of recommendations to the EC, Member States and other local, regional and national organisations and is open for endorsement and implementation from this date onwards.</p>","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 ","pages":"103-108"},"PeriodicalIF":1.5,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41220040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Illario, E Coscioni, V De Luca, M Cataldi, A Postiglione, G Iaccarino
{"title":"Editorial: Multi-Actor Collaboration in Healthcare to Address the Emerging Health Needs of an Aging Population.","authors":"M Illario, E Coscioni, V De Luca, M Cataldi, A Postiglione, G Iaccarino","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 ","pages":"1-4"},"PeriodicalIF":1.1,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141749755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Illario, V. D. Luca, L. Leonardini, M. Kucharczyk, A. S. Parent, Carina Dantas, A. Jegundo, W. V. Staalduinen, J. Ganzarain, L. Comisso, C. Bramezza, A. Carriazo, A. Maritati, G. Tramontano, P. Capozzi, E. Goossens, C. Cotrone, A. Costantini, M. Ciliberti, M. Femiano, A. D'Amore, M. Forlenza, R. Ruggiero, A. Bianchi, L. Augustin, V. Marrazzo, T. D. Ioio, S. Capaldo, A. Crudeli, G. D. Cesare, F. Cuccaro, Giancarlo Bracale, Donatella Tramontano, Alfredo Postiglione, C. Matera, Enrico Coscioni, Jean Bousquet
In February 2017, the “Programma Mattone Internazionale Salute” (ProMis), that is the Italian Program for Internationalization of Regional Health Systems of the Ministry of Health (MoH), presented the first version of its Position Paper on Health Tourism, which embeds a first shared approach to the recommendations expressed by the European Committee of Regions (CoR) on “Age-Friendly” tourism. The CoR stresses the importance of local and regional authorities in the coordination of multi-sectoral policies such as healthcare, social assistance, transport, urban planning and rural development in relation to the promotion of mobility, security, accessibility of services, including health care and social services. “Age-friendly” tourism is an example of an innovative tourist offer that strives to meet the health needs of the entire “traveling” population, with an integrated and cross-sector approach that involves various organizations operating in sectors such as healthcare, accessibility and transport. The aim of the workshop was to explore the interest of the stakeholders to participate in a systemic action in the field of “health” tourism, and to identify priority implementation areas that offer opportunities to take advantage of validated, innovative experiences that strengthen the accessibility to health and social services in regional, national and international contexts. This effort provides the opportunity to take advantage of aligning the European Structural and Investment Funds (ESIF) to the development of tourism, coherently with the needs and resources of local and regional health authorities.
{"title":"Health tourism: an opportunity for sustainable development","authors":"M. Illario, V. D. Luca, L. Leonardini, M. Kucharczyk, A. S. Parent, Carina Dantas, A. Jegundo, W. V. Staalduinen, J. Ganzarain, L. Comisso, C. Bramezza, A. Carriazo, A. Maritati, G. Tramontano, P. Capozzi, E. Goossens, C. Cotrone, A. Costantini, M. Ciliberti, M. Femiano, A. D'Amore, M. Forlenza, R. Ruggiero, A. Bianchi, L. Augustin, V. Marrazzo, T. D. Ioio, S. Capaldo, A. Crudeli, G. D. Cesare, F. Cuccaro, Giancarlo Bracale, Donatella Tramontano, Alfredo Postiglione, C. Matera, Enrico Coscioni, Jean Bousquet","doi":"10.14273/UNISA-2716","DOIUrl":"https://doi.org/10.14273/UNISA-2716","url":null,"abstract":"In February 2017, the “Programma Mattone Internazionale Salute” (ProMis), that is the Italian Program for Internationalization of Regional Health Systems of the Ministry of Health (MoH), presented the first version of its Position Paper on Health Tourism, which embeds a first shared approach to the recommendations expressed by the European Committee of Regions (CoR) on “Age-Friendly” tourism. The CoR stresses the importance of local and regional authorities in the coordination of multi-sectoral policies such as healthcare, social assistance, transport, urban planning and rural development in relation to the promotion of mobility, security, accessibility of services, including health care and social services. “Age-friendly” tourism is an example of an innovative tourist offer that strives to meet the health needs of the entire “traveling” population, with an integrated and cross-sector approach that involves various organizations operating in sectors such as healthcare, accessibility and transport. The aim of the workshop was to explore the interest of the stakeholders to participate in a systemic action in the field of “health” tourism, and to identify priority implementation areas that offer opportunities to take advantage of validated, innovative experiences that strengthen the accessibility to health and social services in regional, national and international contexts. This effort provides the opportunity to take advantage of aligning the European Structural and Investment Funds (ESIF) to the development of tourism, coherently with the needs and resources of local and regional health authorities.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 1","pages":"109 - 115"},"PeriodicalIF":1.5,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48796035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. De Luca, G. Tramontano, C. Del Giudice, I. Grimaldi, R. Romano, I. Liguori, M. Carpinelli Mazzi, N. Di Carluccio, PA Riccio, P. Speranza, A. Iavarone, P. Abete, A. Postiglione, M. Cataldi, C. Vallone, F. Giallauria, A. Cittadini, M. Triggiani, S. Savastano, E. Menditto, L. Leonardini, A. Colao, M. Triassi, G. Iaccarino, A. Postiglione, E. Coscioni, M. Illario
The demographic projections on the European population predict that people aged over 60 will increase by about two million/year in the next decades. Since 2012, the Campania Reference Site of the European Innovation Partnership on Active and Healthy Ageing supports the innovation of the Regional Health System, to face up demographic changes and sustainability. Campania Reference Site provides the opportunity to connect loco-regional stakeholders in social and health care services (universities, healthcare providers, social services, local communities and municipalities), with international organizations, in order to adopt and scale up innovative solutions and approaches. This paper describes the building process of Campania Reference Site and the main results achieved, that have been allowing it to become a hub for open innovation in the field of active and healthy aging at regional, national and international level.
{"title":"Innovative Approaches to Active and Healthy Ageing: Campania Experience to Improve the Adoption of Innovative Good Practices","authors":"V. De Luca, G. Tramontano, C. Del Giudice, I. Grimaldi, R. Romano, I. Liguori, M. Carpinelli Mazzi, N. Di Carluccio, PA Riccio, P. Speranza, A. Iavarone, P. Abete, A. Postiglione, M. Cataldi, C. Vallone, F. Giallauria, A. Cittadini, M. Triggiani, S. Savastano, E. Menditto, L. Leonardini, A. Colao, M. Triassi, G. Iaccarino, A. Postiglione, E. Coscioni, M. Illario","doi":"10.14273/UNISA-2715","DOIUrl":"https://doi.org/10.14273/UNISA-2715","url":null,"abstract":"The demographic projections on the European population predict that people aged over 60 will increase by about two million/year in the next decades. Since 2012, the Campania Reference Site of the European Innovation Partnership on Active and Healthy Ageing supports the innovation of the Regional Health System, to face up demographic changes and sustainability. Campania Reference Site provides the opportunity to connect loco-regional stakeholders in social and health care services (universities, healthcare providers, social services, local communities and municipalities), with international organizations, in order to adopt and scale up innovative solutions and approaches. This paper describes the building process of Campania Reference Site and the main results achieved, that have been allowing it to become a hub for open innovation in the field of active and healthy aging at regional, national and international level.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"19 1","pages":"116 - 123"},"PeriodicalIF":1.5,"publicationDate":"2019-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45875018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号