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Autonomous Drug Discovery with Parallel Intelligence 并行智能的自主药物发现
IF 19.2 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-08-20 DOI: 10.1109/JAS.2025.125426
Fei Lin;Jing Yang;Dali Sun;Levente Kovács;Fei-Yue Wang
Dear Editor, The 2024 Nobel Prize in Chemistry was awarded to David Baker, Demis Hassabis, and John Jumper, recognizing their groundbreaking contributions to protein design and the prediction of complex protein structures [1]. This accomplishment advances the frontier of “Artificial Intelligence (AI) for Science”. It marks a milestone in studying complex systems, highlighting a shift in scientific exploration from traditional causal inference to a comprehensive approach centered on solving complex system problems.
尊敬的编辑:2024年诺贝尔化学奖授予了大卫·贝克、戴米斯·哈萨比斯和约翰·跳普,以表彰他们在蛋白质设计和复杂蛋白质结构预测方面的开创性贡献。这一成就推进了“科学用人工智能”的前沿。它标志着复杂系统研究的一个里程碑,突出了科学探索从传统的因果推理到以解决复杂系统问题为中心的综合方法的转变。
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引用次数: 0
Machine Learning-Based Prediction of Depressive Disorders via Various Data Modalities: A Survey 基于机器学习的抑郁症预测:通过各种数据模式:一项调查
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-02 DOI: 10.1109/JAS.2025.125393
Qiong Li;Xiaotong Liu;Xuecai Hu;Md Atiqur Rahman Ahad;Min Ren;Li Yao;Yongzhen Huang
Depression, a pervasive mental health disorder, has substantial impacts on both individuals and society. The conventional approach to predicting depression necessitates substantial collaboration between health care professionals and patients, leaving room for the influence of subjective factors. Consequently, it is imperative to develop a more efficient and accessible prediction methodology for depression. In recent years, numerous investigations have delved into depression prediction techniques, employing diverse data modalities and yielding notable advancements. Given the rapid progression of this domain, the present article comprehensively reviews major breakthroughs in depression prediction, encompassing multiple data modalities such as electrophysiological signals, brain imaging, audiovisual data, and text. By integrating depression prediction methods from various data modalities, it offers a comparative assessment of their advantages and limitations, providing a well-rounded perspective on how different modalities can complement each other for more accurate and holistic depression prediction. The survey begins by examining commonly used datasets, evaluation metrics, and methodological frameworks. For each data modality, it systematically analyzes traditional machine learning methods alongside the increasingly prevalent deep learning approaches, providing a comparative assessment of detection frameworks, feature representations, context modeling, and training strategies. Finally, the survey culminates with the identification of prospective avenues that warrant further exploration. It provides researchers with valuable insights and practical guidance to advance the field of depression prediction.
抑郁症是一种普遍存在的精神健康障碍,对个人和社会都有重大影响。预测抑郁症的传统方法需要卫生保健专业人员和患者之间的大量合作,为主观因素的影响留下了空间。因此,开发一种更有效、更容易获得的抑郁症预测方法势在必行。近年来,许多研究都深入研究了抑郁预测技术,采用了不同的数据模式,并取得了显著的进展。鉴于这一领域的快速发展,本文全面回顾了抑郁症预测方面的重大突破,包括多种数据模式,如电生理信号、脑成像、视听数据和文本。通过整合来自不同数据模式的抑郁症预测方法,对其优势和局限性进行比较评估,提供一个全面的视角,了解不同模式如何相互补充,以更准确、更全面地预测抑郁症。调查从检查常用的数据集、评估指标和方法框架开始。对于每种数据模式,它系统地分析了传统的机器学习方法以及日益流行的深度学习方法,提供了检测框架、特征表示、上下文建模和训练策略的比较评估。最后,调查最终确定了值得进一步探索的潜在途径。它为研究人员提供了有价值的见解和实践指导,以推进抑郁症预测领域。
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引用次数: 0
Nash Bargaining Solution-Based Multi-Objective Model Predictive Control for Constrained Interactive Robots 基于Nash议价解的约束交互机器人多目标模型预测控制
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-02 DOI: 10.1109/JAS.2024.124398
Minglei Zhu;Jun Qi
Dear Editor, This letter proposes a novel Nash bargaining solution-based multi-objective model predictive control (MPC) scheme to deal with the interaction force control and the path-following problem of the constrained interactive robot. Considering the elastic interaction force model, a mechanical trade-off always exists between the interaction force and position, which means that neither force nor path following can satisfy their desired demands completely. Based on this consideration, two irreconcilable control specifications, the force object function and the position track object function, are proposed, and a new multi-objective MPC scheme is then designed. At each sampling interval, the control action is chosen automatically among the set of Pareto optimal solutions with the Nash bargaining solution from the cooperative game theory. Furthermore, we set state and control constraints to consider physical limitations. The proposed controller's efficacy is demonstrated through simulations on a constrained interactive robot.
本文提出了一种新颖的基于纳什议价解的多目标模型预测控制(MPC)方案,用于处理约束交互机器人的交互力控制和路径跟踪问题。在弹性相互作用力模型中,相互作用力和位置之间总是存在一种力学权衡,即力和路径跟随都不能完全满足期望的要求。在此基础上,提出了力目标函数和位置轨迹目标函数两个不可调和的控制规范,并设计了一种新的多目标MPC方案。在每个采样区间内,控制动作自动从具有合作博弈纳什议价解的帕累托最优解集合中选择。此外,我们设置状态和控制约束来考虑物理限制。通过约束交互机器人的仿真验证了该控制器的有效性。
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引用次数: 0
Hybrid Event-Triggered Control with Stability Analysis 混合事件触发控制与稳定性分析
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-02 DOI: 10.1109/JAS.2024.125067
Ding Wang;Lingzhi Hu;Junfei Qiao
In this paper, a novel hybrid event-triggered control (ETC) method is developed based on the online action-critic technique, which aims at tackling the optimal regulation problem of discrete-time nonlinear systems. In order to ensure the normal execution of the online learning algorithm, a stability criterion condition is created to obtain the initial admissible control policy by using an offline iterative method under the time-triggered control framework. Subsequently, a general triggering condition is designed based on the uniform ultimate boundedness of the controlled system. In order to determine a constant interval which can ensure the system stability, another triggering condition is introduced and the asymptotic stability of the closed-loop system satisfying this condition is analyzed from the perspective of the input-to-state stability. The designed online hybrid ETC method not only further improves control efficiency, but also avoids the continuous judgment of the corresponding triggering condition. In addition, the event-based control law can approach the optimal control input within a finite approximation error. Finally, two experimental examples with physical background are conducted to indicate the present results.
针对离散非线性系统的最优调节问题,提出了一种基于在线动作批评技术的混合事件触发控制方法。为了保证在线学习算法的正常执行,在时间触发控制框架下,采用离线迭代法,创建了一个稳定性判据条件来获得初始的可接受控制策略。然后,基于被控系统的一致极限有界性,设计了一般触发条件。为了确定一个能保证系统稳定的恒定区间,引入了另一个触发条件,并从输入-状态稳定性的角度分析了满足此条件的闭环系统的渐近稳定性。所设计的在线混合ETC方法不仅进一步提高了控制效率,而且避免了对相应触发条件的连续判断。此外,基于事件的控制律可以在有限的近似误差范围内逼近最优控制输入。最后,通过两个具有物理背景的实验实例来验证本文的结果。
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引用次数: 0
Hierarchical Secure Steering Control of In-Wheel Motor Driven Electric Vehicle Under Cyber-Physical Constraints 网络物理约束下轮毂电机驱动电动汽车分层安全转向控制
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-01 DOI: 10.1109/JAS.2023.124092
Zifan Gao;Dawei Zhang;Shuqian Zhu
Dear Editor, This letter presents a new secure hierarchical control strategy for steering tracking of in-wheel motor driven (IWMD) electric vehicle (EV) subject to limited network resources, hybrid cyber-attacks, model nonlinearities, actuator redundancy and airflow disturbance. A hierarchical control architecture is proposed specifically for solving the problems of nonlinear system modeling and actuator redundancy. By utilizing the advantages of fully actuated system (FAS) approach, a nonlinear virtual controller against airflow disturbance is constructed in upper layer system and an event-triggered nonlinear distributed controller is proposed in lower layer system under stochastic hybrid cyber-attacks. A case study of overtaking task is carried out to validate the FAS-based hierarchical control strategy.
这封信提出了一种新的安全层次控制策略,用于轮毂电机驱动(IWMD)电动汽车(EV)的转向跟踪,该控制策略受网络资源有限、混合网络攻击、模型非线性、执行器冗余和气流干扰的影响。针对非线性系统建模和执行器冗余问题,提出了一种分层控制体系结构。利用全驱动系统(FAS)方法的优点,在上层系统中构造了针对气流扰动的非线性虚拟控制器,在下层系统中提出了针对随机混合网络攻击的事件触发非线性分布式控制器。以超车任务为例,验证了基于fass的分级控制策略。
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引用次数: 0
Prescribed Performance Control of Nonlinear Systems With Unknown Sign-Switching Virtual Control Coefficients 未知符号切换虚拟控制系数非线性系统的规定性能控制
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-01 DOI: 10.1109/JAS.2025.125135
Jin-Zi Yang;Jin-Xi Zhang;Tianyou Chai
The problem of high-performance tracking control for the lower-triangular systems with unknown sign-switching virtual control coefficients as well as unmatched disturbances is investigated in this paper. Instead of the online estimation algorithm, the sliding mode method and the Nussbaum gain technique, a group of orientation functions are employed to handle the unknown sign-switching virtual control coefficients. The control law is combined with the orientation functions and the barrier functions lumped in a recursive manner. It achieves output tracking with the preassigned rate, overshoot, and accuracy. In contrast with the existing solutions, it is effective for the nearly model-free case, with the requirement for information of neither the system nonlinearities nor their bounding functions of the plant, nor the bounds of the disturbances. In addition, our controller exhibits significant simplicity, without parameter identification, disturbance estimation, function approximation, derivative calculation, dynamic surfaces, or command filtering. Two simulation examples are conducted to substantiate the efficacy and advantages of our approach.
研究了具有未知符号交换虚拟控制系数和不匹配干扰的下三角形系统的高性能跟踪控制问题。采用一组方向函数来处理未知的切换信号虚拟控制系数,而不是采用在线估计算法、滑模方法和努斯鲍姆增益技术。将控制律与方向函数和障碍函数以递归方式组合起来。它实现输出跟踪与预分配的速率,超调,和精度。与已有的解相比,该方法对几乎无模型的情况是有效的,既不需要系统非线性信息,也不需要对象的边界函数信息,也不需要扰动的边界信息。此外,我们的控制器具有显著的简单性,无需参数识别,干扰估计,函数逼近,导数计算,动态曲面或命令滤波。通过两个仿真实例验证了该方法的有效性和优越性。
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引用次数: 0
Federated Experiments: Generative Causal Inference Powered by LLM-Based Agents Simulation and RAG-Based Domain Docking 联邦实验:基于llm的agent仿真和基于rag的领域对接驱动的生成因果推理
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-01 DOI: 10.1109/JAS.2024.124671
De-Yu Zhou;Xiao Xue;Qun Ma;Chao Guo;Li-Zhen Cui;Yong-Lin Tian;Jing Yang;Fei-Yue Wang
Computational experiments method is an essential tool for analyzing, designing, managing, and integrating complex systems. However, a significant challenge arises in constructing agents with human-like characteristics to form an AI society. Agent modeling typically encompasses four levels: 1) The autonomy features of agents, e.g., perception, behavior, and decision-making; 2) The evolutionary features of agents, e.g., bounded rationality, heterogeneity, and learning evolution; 3) The social features of agents, e.g., interaction, cooperation, and competition; 4) The emergent features of agents, e.g., gaming with environments or regulatory strategies. Traditional modeling techniques primarily derive from ABMs (Agent-based Models) and incorporate various emerging technologies (e.g., machine learning, big data, and social networks), which can enhance modeling capabilities, while amplifying the complexity [1].
计算实验方法是分析、设计、管理和集成复杂系统的重要工具。然而,在构建具有人类特征的智能体以形成人工智能社会方面,出现了一个重大挑战。智能体建模通常包括四个层次:1)智能体的自主性特征,如感知、行为和决策;2)智能体的进化特征,如有限理性、异质性和学习进化;3)主体的社会特征,如互动、合作、竞争等;4)代理的突现特征,例如,与环境或监管策略的博弈。传统的建模技术主要来源于ABMs(基于代理的模型),并结合了各种新兴技术(如机器学习、大数据和社交网络),这些技术可以增强建模能力,同时放大复杂性[1]。
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引用次数: 0
A Learning-Based Passive Resilient Controller for Cyber-Physical Systems: Countering Stealthy Deception Attacks and Complete Loss of Actuators Control Authority 一种基于学习的网络物理系统被动弹性控制器:对抗隐形欺骗攻击和执行器控制权限完全丧失
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-01 DOI: 10.1109/JAS.2024.124683
Liang Xin;Zhi-Qiang Long
Cyber-physical systems (CPSs) are increasingly vulnerable to cyber-attacks due to their integral connection between cyberspace and the physical world, which is augmented by Internet connectivity. This vulnerability necessitates a heightened focus on developing resilient control mechanisms for CPSs. However, current observer-based active compensation resilient controllers exhibit poor performance against stealthy deception attacks (SDAs) due to the difficulty in accurately reconstructing system states because of the stealthy nature of these attacks. Moreover, some non-active compensation approaches are insufficient when there is a complete loss of actuator control authority. To address these issues, we introduce a novel learning-based passive resilient controller (LPRC). Our approach, unlike observer-based state reconstruction, shows enhanced effectiveness in countering SDAs. We developed a safety state set, represented by an ellipsoid, to ensure CPS stability under SDA conditions, maintaining system trajectories within this set. Additionally, by employing deep reinforcement learning (DRL), the LPRC acquires the capacity to adapt and diverse evolving attack strategies. To empirically substantiate our methodology, various attack methods were compared with current passive and active compensation resilient control methods to evaluate their performance.
网络物理系统(cps)越来越容易受到网络攻击,因为它们将网络空间与物理世界联系在一起,而互联网的连接又增强了这种联系。这一脆弱性需要高度重视为cps开发有弹性的控制机制。然而,目前基于观测器的主动补偿弹性控制器在面对隐身欺骗攻击(SDAs)时表现出较差的性能,这是由于这些攻击的隐蔽性导致难以准确重建系统状态。此外,当执行器控制权限完全丧失时,一些非主动补偿方法是不够的。为了解决这些问题,我们引入了一种新的基于学习的被动弹性控制器(LPRC)。与基于观测器的状态重建不同,我们的方法在对抗sda方面显示出更高的有效性。我们开发了一个由椭球表示的安全状态集,以确保CPS在SDA条件下的稳定性,并在该集合内保持系统轨迹。此外,通过采用深度强化学习(DRL), LPRC获得了适应和多样化不断发展的攻击策略的能力。为了实证验证我们的方法,我们将各种攻击方法与现有的被动和主动补偿弹性控制方法进行了比较,以评估其性能。
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引用次数: 0
DoS Attack Schedules for Remote State Estimation in CPSs with Two-Hop Relay Networks Under Round-Robin Protocol 轮循协议下两跳中继网络cps远程状态估计的DoS攻击调度
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-01 DOI: 10.1109/JAS.2024.124755
Shuo Zhang;Lei Miao;Xudong Zhao
Dear Editor, This letter investigates the optimal denial-of-service (DoS) attack scheduling targeting state estimation in cyber-Physical systems (CPSs) with the two-hop multi-channel network. CPSs are designed to achieve efficient, secure and adaptive operation by embedding intelligent and autonomous decision-making capabilities in the physical world. As a key component of the CPSs, the wireless network is vulnerable to various malicious attacks due to its openness [1]. DoS attack is one of the most common attacks, characterized of simple execution and significant destructiveness [2]. To mitigate the economic losses and environmental damage caused by DoS attacks, it is crucial to model and investigate data transmissions in CPSs.
这封信研究了两跳多通道网络中网络物理系统(cps)中针对状态估计的最优拒绝服务(DoS)攻击调度。cps旨在通过在物理世界中嵌入智能和自主决策能力来实现高效、安全和自适应的操作。无线网络作为cps的关键组成部分,由于其开放性b[1],极易受到各种恶意攻击。DoS攻击是最常见的攻击之一,具有执行简单、破坏性大等特点。为了减轻DoS攻击造成的经济损失和环境破坏,对cps中的数据传输进行建模和研究至关重要。
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引用次数: 0
A Robust Large-Scale Multiagent Deep Reinforcement Learning Method for Coordinated Automatic Generation Control of Integrated Energy Systems in a Performance-Based Frequency Regulation Market 基于性能的频率调节市场中集成能源系统协调自动发电控制的鲁棒大规模多智能体深度强化学习方法
IF 15.3 1区 计算机科学 Q1 AUTOMATION & CONTROL SYSTEMS Pub Date : 2025-07-01 DOI: 10.1109/JAS.2024.124482
Jiawen Li;Tao Zhou
To enhance the frequency stability and lower the regulation mileage payment of a multiarea integrated energy system (IES) that supports the power Internet of Things (IoT), this paper proposes a data-driven cooperative method for automatic generation control (AGC). The method consists of adaptive fractional-order proportional-integral (FOPI) controllers and a novel efficient integration exploration multiagent twin delayed deep deterministic policy gradient (EIE-MATD3) algorithm. The FOPI controllers are designed for each area based on the performance-based frequency regulation market mechanism. The EIE-MATD3 algorithm is used to tune the coefficients of the FOPI controllers in real time using centralized training and decentralized execution. The algorithm incorporates imitation learning and efficient integration exploration to obtain a more robust coordinated control strategy. An experiment on the four-area China Southern Grid (CSG) real-time digital system shows that the proposed method can improve the control performance and reduce the regulation mileage payment of each area in the IES.
为了提高支持电力物联网的多区域集成能源系统(IES)的频率稳定性和降低调节里程支付,提出了一种数据驱动的自动发电控制(AGC)协同方法。该方法由自适应分数阶比例积分(FOPI)控制器和一种新的高效集成探索多智能体双延迟深度确定性策略梯度(EIE-MATD3)算法组成。基于基于性能的频率调节市场机制,为每个区域设计了FOPI控制器。采用EIE-MATD3算法集中训练、分散执行,实时调整FOPI控制器的系数。该算法结合了模仿学习和高效的集成探索,获得了更鲁棒的协调控制策略。在南方电网四区实时数字系统上进行的实验表明,该方法可以提高控制性能,降低电网各区域的调节里程支付。
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引用次数: 0
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Ieee-Caa Journal of Automatica Sinica
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