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Microbiome-Modifiers for Cancer-Related Fatigue Management: A Systematic Review 用于缓解癌症相关疲劳的微生物调节剂:系统综述。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151619
Silvia Belloni , Rosario Caruso , Chiara Giacon , Irene Baroni , Gianluca Conte , Arianna Magon , Cristina Arrigoni

Objectives

This study systematically investigates the evidence regarding the use of probiotics in managing cancer-related fatigue (CRF).

Study Design

We conducted a systematic review of randomized controlled trials.

Data Sources

The systematic search encompassed six databases: PubMed, CINHAL, Cochrane Database of Systematic Reviews, Web of Science, Scopus, and EMBASE, covering the period from inception to December 2023. The assessment of risk of bias employed the Cochrane risk of bias tool (RoB 2). A narrative synthesis and an exploratory meta-analysis were conducted to summarize the evidence.

Results

Among 460 records, three studies met the eligibility criteria and were included in the review. These studies involved a total of 284 participants with colorectal and breast cancer. One study demonstrated a marginal improvement in CRF postchemotherapy in colorectal cancer patients using probiotics. Another study, also using probiotics, reported a significant reduction in CRF among colorectal cancer patients undergoing chemotherapy. Additionally, a study employing synbiotics showed a substantial decrease in CRF severity in breast cancer patients receiving chemotherapy.

Conclusion

The study presents initial but varied evidence suggesting the potential of probiotics and synbiotics as adjunctive therapies in managing CRF alongside anticancer treatments.

Implications for Nursing Practice

In nursing practice, large-scale clinical trials are urgently needed to evaluate the effectiveness of probiotics in treating cancer-related fatigue during cancer therapy. Insights from this review could guide nurses in selecting appropriate probiotic strains and integrating microbiome modifiers into comprehensive care plans, potentially enhancing the quality of life for cancer patients.

研究目的本研究系统地调查了使用益生菌控制癌症相关疲劳(CRF)的证据:研究设计:我们对随机对照试验进行了系统回顾:数据来源:我们对随机对照试验进行了系统性回顾:PubMed、CINHAL、Cochrane 系统综述数据库、Web of Science、Scopus 和 EMBASE,检索期从开始到 2023 年 12 月。偏倚风险评估采用了 Cochrane 偏倚风险工具(RoB 2)。对证据进行了叙述性综合和探索性荟萃分析:在 460 条记录中,有三项研究符合资格标准并被纳入综述。这些研究共涉及 284 名结直肠癌和乳腺癌患者。其中一项研究表明,使用益生菌后,结直肠癌患者化疗后的CRF略有改善。另一项同样使用益生菌的研究报告称,接受化疗的结直肠癌患者的 CRF 显著降低。此外,一项使用益生菌的研究显示,接受化疗的乳腺癌患者的 CRF 严重程度大幅降低:本研究提供了初步但不同的证据,表明益生菌和合成益生菌有可能作为辅助疗法,在抗癌治疗的同时控制 CRF:在护理实践中,迫切需要进行大规模的临床试验,以评估益生菌在治疗癌症过程中治疗癌症相关疲劳的效果。本综述的观点可指导护士选择合适的益生菌菌株,并将微生物组调节剂纳入综合护理计划,从而提高癌症患者的生活质量。
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引用次数: 0
Navigating Through Disaster: Application of Oncology Nurse Navigator Competencies to Climate Disaster Preparation and Response 灾难导航:将肿瘤科护士导航员的能力应用于气候灾害的准备和应对。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151581
Ryne Wilson , Darcy Burbage , Erin Dickman , Pam Ginex

Objectives

The role of the oncology nurse navigator (ONN) before, during, and after a climate disaster is critical to ensuring that individuals with cancer continue to receive the necessary care and support. The objective of this article is to provide an overview of the essential role of the ONN by highlighting the application of core competencies to climate disasters.

Methods

Competencies available for ONNs from the Oncology Nursing Society include coordination of care, communication, education, professional role, and expertise. International Council of Nurses (ICN) core competencies for disaster nursing include eight domains: preparation and planning, communication, incident management systems, safety and security, assessment, intervention, recovery, and law and ethics. These competencies are explored for application to climate disaster preparation, mitigation, and response.

Results

The ONN competencies and the domains of the ICN disaster nursing competencies were integrated to outline the role of the ONN in disaster preparedness and response.

Conclusion

The ONN is pivotal in maintaining the continuity of cancer care. The ONN's expertise is critical for navigating the difficulties presented by hurricanes, floods, wildfires, and other extreme climate events as well as existing barriers to cancer care. The ONN's adeptness at coordinating care, communicating effectively, and tapping into community resources will transfer to a climate disaster, ensuring minimal treatment interruptions and access to necessary care.

Implications for Nursing Practice

The ONN is integral to the cancer care team in preparing and responding to climate disasters. The ONN ensures ongoing access to cancer care and advocates for the specialized care that people with cancer need. The ONS ONN Core Competencies and the ICN Disaster Competencies are applicable for developing processes and procedures to address climate disasters in clinical practice.

目标:肿瘤科护士导航员(ONN)在气候灾害发生之前、期间和之后的作用对于确保癌症患者继续获得必要的护理和支持至关重要。本文旨在通过强调核心能力在气候灾害中的应用,概述肿瘤科护士导航员的重要作用:方法:肿瘤护理学会为 ONNs 提供的能力包括护理协调、沟通、教育、专业角色和专业知识。国际护士理事会(ICN)的灾难护理核心能力包括八个领域:准备与规划、沟通、事件管理系统、安全与安保、评估、干预、恢复以及法律与道德。我们探讨了这些能力在气候备灾、减灾和应灾中的应用:结果:综合了 ONN 能力和 ICN 灾难护理能力的领域,概述了 ONN 在备灾和应灾中的作用:结论: ONN 在保持癌症护理的连续性方面至关重要。ONN 的专业知识对于克服飓风、洪水、野火和其他极端气候事件带来的困难以及癌症护理的现有障碍至关重要。ONN 擅长协调护理、有效沟通和利用社区资源,这一点将在气候灾难中得以体现,从而确保将治疗中断和获得必要护理的可能性降至最低:ONN 是癌症护理团队准备和应对气候灾难不可或缺的一部分。ONN 确保持续获得癌症护理,并倡导为癌症患者提供所需的专门护理。ONS ONN 核心能力和 ICN 灾难能力适用于在临床实践中制定应对气候灾难的流程和程序。
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引用次数: 0
Cancer Patient Navigation in Canada: Directions From the North 加拿大癌症患者导航:来自北方的方向。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151588
Sarah Champ , Catherine Dixon

Objectives

Cancer is a complex disease that is experienced by those affected by cancer and their loved ones differently. The importance of cancer patient navigation is quintessential to support those affected through the healthcare system and to supportive resources. Canadian cancer statistics advise of the continued increase of cancer and impacts on health care. With Canada being a large geographical area, large portions of the population live in rural and remote areas with decreased access to health services. In Canada, cancer navigation is different across the country; each province's or territory's health authority creates their own cancer navigation program based on the needs of their patients. This report aims to provide an overview of cancer in Canada, along with the different navigation programs available nationally. Additionally, it will review the role the Canadian Association of Nurses in Oncology/Association canadienne des infirmières en oncologie (CANO/ACIO) plays in creating a community of practice to support cancer patient navigators across the country.

Methods

The information on various provincial and territorial navigation programs was obtained through discussion with the CANO/ACIO Navigation Special Interest Group (SIG). All provinces and territories were interviewed with the exception of Quebec, Prince Edward Island, Nunavut, and Yukon.

Results

While the vast majority of navigation has a similar core intent, there are many differences between the provinces and territories in the navigation programs. These differences are based on geographical need and the individual health authorities.

Conclusions

The Canadian Association of Nurses in Oncology/Association canadienne des infirmières en oncologie (CANO/ACIO) provides a community for cancer navigators to connect through a Special Interest Group (SIG), meeting virtually monthly to support each other across Canada to collaborate, identify issues, trends, and challenges.

Implications for Nursing Practice

Cancer patient navigation is a valuable resource for all individuals with cancer and their loved ones, particularly when faced with difficulties accessing care in rural and remote areas. Cancer patient navigators' scope is similar in intent, despite potential differences in programs. By connecting with other navigators through the CANO/ACIO navigation SIG, navigators across the country can provide a connection to discuss program similarities and barriers and opportunities for cancer navigation programs to work together to support each other and evolve their programs to meet the needs of their provincial and territorial residents.

目标:癌症是一种复杂的疾病,癌症患者及其亲人会有不同的感受。癌症患者导航对于通过医疗保健系统和支持性资源为患者提供支持至关重要。加拿大癌症统计数据表明,癌症发病率持续上升,并对医疗保健产生影响。加拿大幅员辽阔,大部分人口居住在农村和偏远地区,获得医疗服务的机会较少。在加拿大,癌症导航在全国各地都有所不同;每个省或地区的卫生当局都会根据患者的需求制定自己的癌症导航计划。本报告旨在概述加拿大的癌症情况,以及全国范围内不同的导航计划。此外,报告还将回顾加拿大肿瘤护士协会/加拿大肿瘤信息协会(CANO/ACIO)在创建实践社区以支持全国癌症患者导航员方面所发挥的作用:通过与 CANO/ACIO 导航特别兴趣小组(SIG)讨论,获得了各省和地区导航计划的信息。除魁北克省、爱德华王子岛省、努纳武特地区和育空地区外,所有省份和地区都接受了采访:虽然绝大多数导航的核心意图相似,但各省和地区之间的导航计划存在许多差异。这些差异是基于地域需求和各个卫生机构:加拿大肿瘤护士协会/加拿大肿瘤医务人员协会(CANO/ACIO)通过特别兴趣小组(SIG)为癌症导航人员提供了一个联系社区,每月举行一次虚拟会议,以支持加拿大各地的相互合作,确定问题、趋势和挑战:癌症患者导航是所有癌症患者及其亲人的宝贵资源,尤其是在农村和偏远地区难以获得护理服务的情况下。尽管项目可能存在差异,但癌症患者导航员的工作范围在意图上是相似的。通过 CANO/ACIO 导航 SIG 与其他导航员建立联系,全国各地的导航员可以建立联系,讨论项目的相似性和障碍,以及癌症导航项目的合作机会,以相互支持和发展他们的项目,满足各省和地区居民的需求。
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引用次数: 0
Supporting Cancer Survivors Following Treatment for Non-Hodgkin's and Hodgkin's Lymphoma: A Pilot Study Assessing the Feasibility and Process Outcomes of a Nurse-Led Intervention 为接受非霍奇金淋巴瘤和霍奇金淋巴瘤治疗的癌症幸存者提供支持:评估护士主导干预措施的可行性和过程结果的试点研究。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151592
Amy J. Spooner , Jane Turner , Elise Button , Patsy Yates , Glen Kennedy , Jason Butler , Natalie Bradford , Alexandre Chan , Nicolas H. Hart , Raymond J. Chan

Objective

Lymphoma is the sixth most common cancer in Australia and comprises 2.8% of worldwide cancer diagnoses. Research targeting development and evaluation of post-treatment care for debilitating complications resulting from the disease and its treatment is limited. This study aimed to assess the feasibility and acceptability of a nurse-led survivorship intervention, post-treatment in Hodgkin's and non-Hodgkin's lymphoma survivors.

Methods

A single-center, prospective, 3-arm, pilot, randomized controlled, parallel-group trial was used. People with lymphoma were recruited and randomized to the intervention (ENGAGE), education booklet only, or usual care arm. Participants receiving ENGAGE received an educational booklet and were offered 3 consultations (via various modes) with a cancer nurse to develop a survivorship care plan and healthcare goals. Participant distress and intervention acceptability was measured at baseline and 12-wk. Acceptability was measured via a satisfaction survey using a 11-point scale. Feasibility was measured using participation, retention rates, and process outcomes. Data were analyzed using descriptive statistics.

Results

Thirty-four participants with HL and NHL were recruited to the study (11 = intervention, 11 = information only, 12 = usual care). Twenty-seven participants (79%) completed all time points from baseline to 12 wk. Seven (88%) of the 8 participants receiving ENGAGE completed all consultations using various modes to communicate with the nurse (videoconference 14/23, 61%; phone 5/23, 22%; face-to-face 4/23, 17%). Participants who completed the intervention were highly satisfied with ENGAGE.

Conclusion

The ENGAGE intervention is feasible and highly acceptable for lymphoma survivors. These findings will inform a larger trial assessing effectiveness and cost effectiveness of ENGAGE.

目的:淋巴瘤是澳大利亚第六大常见癌症,占全球癌症诊断的 2.8%。针对该疾病及其治疗所导致的衰弱性并发症的治疗后护理的开发和评估研究十分有限。本研究旨在评估霍奇金淋巴瘤和非霍奇金淋巴瘤幸存者治疗后由护士主导的幸存者干预措施的可行性和可接受性:方法:采用单中心、前瞻性、三臂、试点、随机对照、平行组试验。淋巴瘤患者被招募并随机分配到干预组(ENGAGE)、仅接受教育手册组或常规护理组。接受ENGAGE治疗的参与者会收到一本教育手册,并与癌症护士进行3次咨询(通过各种方式),以制定幸存者护理计划和保健目标。在基线和 12 周时对参与者的痛苦和干预的可接受性进行测量。可接受性通过满意度调查进行测量,采用 11 分制。可行性通过参与率、保留率和过程结果来衡量。数据采用描述性统计进行分析:研究招募了 34 名患有 HL 和 NHL 的参与者(11 名 = 干预,11 名 = 仅提供信息,12 名 = 常规护理)。27名参与者(79%)完成了从基线到12周的所有时间点。在接受 ENGAGE 的 8 位参与者中,有 7 位(88%)完成了所有咨询,他们使用各种模式与护士沟通(视频会议 14/23,61%;电话 5/23,22%;面对面 4/23,17%)。完成干预的参与者对ENGAGE非常满意:结论:ENGAGE 干预是可行的,淋巴瘤幸存者的接受度很高。这些发现将为评估ENGAGE有效性和成本效益的更大规模试验提供参考。
{"title":"Supporting Cancer Survivors Following Treatment for Non-Hodgkin's and Hodgkin's Lymphoma: A Pilot Study Assessing the Feasibility and Process Outcomes of a Nurse-Led Intervention","authors":"Amy J. Spooner ,&nbsp;Jane Turner ,&nbsp;Elise Button ,&nbsp;Patsy Yates ,&nbsp;Glen Kennedy ,&nbsp;Jason Butler ,&nbsp;Natalie Bradford ,&nbsp;Alexandre Chan ,&nbsp;Nicolas H. Hart ,&nbsp;Raymond J. Chan","doi":"10.1016/j.soncn.2024.151592","DOIUrl":"10.1016/j.soncn.2024.151592","url":null,"abstract":"<div><h3>Objective</h3><p>Lymphoma is the sixth most common cancer in Australia and comprises 2.8% of worldwide cancer diagnoses. Research targeting development and evaluation of post-treatment care for debilitating complications resulting from the disease and its treatment is limited. This study aimed to assess the feasibility and acceptability of a nurse-led survivorship intervention, post-treatment in Hodgkin's and non-Hodgkin's lymphoma survivors.</p></div><div><h3>Methods</h3><p>A single-center, prospective, 3-arm, pilot, randomized controlled, parallel-group trial was used. People with lymphoma were recruited and randomized to the intervention (ENGAGE), education booklet only, or usual care arm. Participants receiving ENGAGE received an educational booklet and were offered 3 consultations (via various modes) with a cancer nurse to develop a survivorship care plan and healthcare goals. Participant distress and intervention acceptability was measured at baseline and 12-wk. Acceptability was measured via a satisfaction survey using a 11-point scale. Feasibility was measured using participation, retention rates, and process outcomes. Data were analyzed using descriptive statistics.</p></div><div><h3>Results</h3><p>Thirty-four participants with HL and NHL were recruited to the study (11 = intervention, 11 = information only, 12 = usual care). Twenty-seven participants (79%) completed all time points from baseline to 12 wk. Seven (88%) of the 8 participants receiving ENGAGE completed all consultations using various modes to communicate with the nurse (videoconference 14/23, 61%; phone 5/23, 22%; face-to-face 4/23, 17%). Participants who completed the intervention were highly satisfied with ENGAGE.</p></div><div><h3>Conclusion</h3><p>The ENGAGE intervention is feasible and highly acceptable for lymphoma survivors. These findings will inform a larger trial assessing effectiveness and cost effectiveness of ENGAGE.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0749208124000135/pdfft?md5=1c278c4b794215efb54131cde6d473ba&pid=1-s2.0-S0749208124000135-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Nurse-Led Supportive Care Program on Quality of Life in Women with Breast Cancer Receiving Adjuvant Chemotherapy: A Randomized Controlled Pilot Study 护士指导的支持性护理计划对接受辅助化疗的乳腺癌妇女生活质量的影响:随机对照试验研究》。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151609
Banu Yazicioglu Kucuk , Pinar Zorba Bahceli

Objectives

This study was to evaluate the effects of nurse-led supportive care program on quality of life in women with breast cancer receiving adjuvant chemotherapy.

Methods

The study was carried out a parallel group randomized controlled pilot study with repeated-measures design in general surgery unit of a training and research hospital. Forty-two women with newly diagnosed breast cancer were randomly assigned to the intervention and control groups. The intervention group received nurse-led supportive care program for 8 weeks, 4 weeks in face-to-face sessions and 4 weeks through phone sessions. The control group received only routine treatment. The women in both groups completed the EORTC-QLQ-C30 (version 3.0) Quality of Life questionnaires at baseline and ninth week.

Results

There was a significant increase in the mean global health status and functional status scores of the women with breast cancer in the intervention group compared to the women in the control group in the ninth week compared to the baseline. The women in the intervention group had a lower mean symptom status score in the ninth week than the women in the control group and there was a statistically significant difference in the change in the mean scores of the groups over time.

Conclusions

Our nurse-led supportive care program is an effective, safe and acceptable method to support women with BC receiving adjuvant chemotherapy.

Implications for Nursing Practice

The nurse-led supportive care program can be used as a reliable and effective nursing intervention to increase the quality of life of women breast cancer receiving adjuvant chemotherapy.

Clinical Trial Registration

NCT05399160.

研究目的本研究旨在评估护士主导的支持性护理项目对接受辅助化疗的乳腺癌女性患者生活质量的影响:本研究在一家培训和研究医院的普外科开展了一项采用重复测量设计的平行组随机对照试验研究。42名新确诊的乳腺癌患者被随机分配到干预组和对照组。干预组接受由护士主导的支持性护理计划,为期 8 周,其中 4 周为面对面护理,4 周为电话护理。对照组只接受常规治疗。两组妇女分别在基线和第九周完成了 EORTC-QLQ-C30 (3.0 版)生活质量问卷:结果:与对照组相比,干预组乳腺癌妇女在第九周的总体健康状况和功能状况的平均得分与基线相比有明显提高。干预组妇女在第九周的症状状态平均得分低于对照组妇女,而且随着时间的推移,各组平均得分的变化差异有统计学意义:我们以护士为主导的支持性护理计划是一种有效、安全且可接受的方法,可为接受辅助化疗的 BC 妇女提供支持:护士主导的支持性护理计划可作为一种可靠、有效的护理干预措施,提高接受辅助化疗的乳腺癌妇女的生活质量:临床试验注册:NCT05399160。
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引用次数: 0
Cancer Survivors’ and Care Partners’ Audio Diaries on Stress and Social Support Resources During the COVID-19 Pandemic 癌症幸存者和护理伙伴关于 COVID-19 大流行期间压力和社会支持资源的录音日记。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151623
Kristin G. Cloyes , Kelly J. Mansfield , Sarah E. Wawrzynski , Marilisa Vega , Jacqueline Kent-Marvick , Jia-Wen Guo

Objectives

To describe cancer survivors’ and care partners’ perceived stress and social support during the COVID-19 pandemic and assess the feasibility of audio diaries for assessing role-related needs and resources.

Methods

Participants (N = 51; n = 28 survivors, n = 23 care partners) recorded three monthly audio diaries reporting stress and support experiences. Diaries were transcribed and content-analyzed using a hybrid approach. Stress-related content was inductively coded, and social support content was deductively coded by type (instrumental, information, emotional, companionship, appraisal; κ = 0.75) then inductively coded. Descriptive statistics summarized sociodemographic data and compared coding frequencies by role. We developed narrative summaries of stress and support categories and selected quotes for contextual detail.

Results

Cancer-related stressors were most prevalent (28.8%), followed by work (26.8%), family (23.1%), social isolation (13.4%), and finances (8.0%). While no significant difference in reporting frequency was observed between roles, cancer-related stress was more prevalent for survivors while work-related stress was mentioned more by care partners. Emotional support was the most prevalent support type (32.1%), followed by companionship (25.3%), appraisal (17.9%), instrumental (16.67%), and informational support (8%). Survivors reported more appraisal support than care partners (χ2 = 6.48, df = 1, P = .011) and more support for self-care, while care partners expressed more other-oriented concerns and focused more on managing responsibilities and interactions outside the household.

Conclusions

The pandemic complicated and intensified role-based stressors already present in the survivorship context. Our findings highlight the importance of informal social support networks, particularly when access to formal services is limited, and suggest that audio diaries can be an effective tool for assessing support needs and resources.

Implications for Nursing Practice

Nurses and healthcare providers should tailor social support assessments to address the distinct support needs and individual resources of cancer survivors and their care partners. This is especially critical in contexts that limit access to care and formal services.

目的描述癌症幸存者和护理伙伴在 COVID-19 大流行期间感知到的压力和社会支持,并评估音频日记在评估角色相关需求和资源方面的可行性:参与者(N = 51;n = 28 名幸存者,n = 23 名护理伙伴)录制了三份每月语音日记,报告压力和支持体验。采用混合方法对日记进行转录和内容分析。与压力相关的内容进行归纳编码,社会支持内容按类型(工具、信息、情感、陪伴、评价;κ = 0.75)进行演绎编码,然后进行归纳编码。描述性统计汇总了社会人口学数据,并比较了不同角色的编码频率。我们编写了压力和支持类别的叙述性摘要,并选取了一些引文来说明背景细节:癌症相关压力最普遍(28.8%),其次是工作(26.8%)、家庭(23.1%)、社会孤立(13.4%)和经济(8.0%)。虽然不同角色间的报告频率没有明显差异,但幸存者更多提及与癌症相关的压力,而护理伙伴则更多提及与工作相关的压力。情感支持是最普遍的支持类型(32.1%),其次是陪伴(25.3%)、评估(17.9%)、工具性支持(16.67%)和信息支持(8%)。幸存者比护理伙伴报告了更多的评价支持(χ2 = 6.48, df = 1, P = .011)和更多的自我护理支持,而护理伙伴则表达了更多以他人为导向的关注,并更注重管理家庭以外的责任和互动:大流行病使幸存者本已存在的基于角色的压力变得更加复杂和强烈。我们的研究结果强调了非正式社会支持网络的重要性,尤其是在获得正式服务的途径有限的情况下,并表明录音日记可以成为评估支持需求和资源的有效工具:护士和医疗服务提供者应针对癌症幸存者及其护理伙伴的不同支持需求和个人资源,量身定制社会支持评估。在获得护理和正规服务受到限制的情况下,这一点尤为重要。
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引用次数: 0
Oncology Nurse Navigation in Underserved Communities: Opportunities and Future Directions 服务不足社区的肿瘤科护士导航:机遇与未来方向
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151586
Jeannine M. Brant

Objectives

Provide an overview of navigation in three disparate populations: rural, Native American/Alaska Native, and low- to middle-income countries. Discuss gaps in care and opportunities to improve cancer care.

Methods

A literature search was conducted in PubMed and on Google Scholar using search terms, nurse navigation, cancer, disparit*, low- to middle-income countries, Native American, American Indian, and rural. Peer-reviewed research studies, review articles, databases and websites of professional organizations, and historical books were reviewed to provide an overview of oncology nurse navigation in underserved communities. Experiences in working with these populations over the past 30 years were also provided to support current literature.

Results

Forty references were included in this overview of nurse navigation in underserved communities. Nurse navigation in these disparate areas is in its infancy. While some programs exist and outcomes have been positive, their dissemination is sparse. A need exists to expand nurse navigation into these areas to provide care for these underserved communities.

Conclusion

Oncology nursing navigation for each of these underserved communities requires a culturally sensitive approach. Many of these approaches are universal to cultural competency and can be applied to most disparate populations.

Implications for Nursing Practice

Nurses comprise the largest workforce around the globe and are well-equipped to develop navigation programs in some of the most disparate communities around the world. To do so, it is important to use a foundation of building trust, embracing individual differences, providing culturally sensitive education and resources for growth, and good communication.

目标概述在农村、美国原住民/阿拉斯加原住民以及中低收入国家这三种不同人群中的导航情况。方法在 PubMed 和 Google Scholar 上进行文献检索,检索词包括护士导航、癌症、差异*、中低收入国家、美国原住民、美国印第安人和农村。研究人员查阅了同行评议的研究报告、评论文章、专业组织的数据库和网站以及历史书籍,对服务不足社区的肿瘤科护士指导工作进行了概述。此外,还提供了过去 30 年中与这些人群合作的经验,以支持当前的文献。在这些不同的地区,护士导航尚处于起步阶段。虽然已有一些项目并取得了积极成果,但其传播范围却很有限。有必要将护士指导扩展到这些地区,为这些服务不足的社区提供护理服务。结论为这些服务不足的社区提供肿瘤护理指导需要采取文化敏感的方法。对护理实践的启示护士是全球最大的劳动力群体,她们完全有能力在世界上一些最不平等的社区制定导航计划。要做到这一点,重要的是要以建立信任、包容个体差异、提供文化敏感教育和成长资源以及良好沟通为基础。
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引用次数: 0
The Patient Symptom Experience After Tisagenlecleucel and Lisocabtagene Maraleucel CAR T-Cell Therapy for Lymphoma Tisagenlecleucel 和 Lisocabtagene Maraleucel CAR T 细胞疗法治疗淋巴瘤后患者的症状体验。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151614
Lucy Andersen , Kayla M. Baker , Heather Difilippo , Salimah H. Meghani , David Porter , Jie Deng

Objectives

Chimeric Antigen Receptor (CAR) T-cell treatment is associated with several unique toxicities, and the short-term symptom trajectory in the immediately after therapy is well-documented. However, little is known about patients’ long-term symptom experience. The study aimed to elicit the symptom experience of adult patients in remission after CAR T-cell therapy for B cell lymphoma.

Data Sources

A qualitative descriptive design with thematic analysis was utilized. Recruitment occurred at a tertiary academic medical center using the following inclusion criteria: adult recipient of CAR T-cell therapy for B-cell lymphoma between 3 and 12 months prior to enrollment, and currently in remission. Semi-structured interviews were conducted, transcripts were inductively coded, and team members met weekly to ensure rigor. The final sample included 10 patients: Seven received tisagenlecleucel and three received lisocabtagene marleucel and were a median of 169 days post-infusion and 65 years of age.

Conclusions

Participants continued to report symptoms, including fatigue, neuropathy, low endurance, insomnia, memory problems, and pain. Most symptoms improved over time. Some symptoms interfered with social activities, work, driving, and physical activity, though participants reported that most symptoms existed prior to CAR T-cell therapy, and overall, found CAR T-cell therapy acceptable.

Implications for Nursing Practice

Patients in remission after CAR T-cell therapy often continue to experience symptoms. Nurses should continue to assess this growing patient population and determine if patients require additional symptom management or support. Further research is needed to understand long-term symptom trajectory and associations with prior lines of therapy and CAR T-cell therapy.

目的:嵌合抗原受体(CAR)T 细胞治疗与几种独特的毒性有关,治疗后的短期症状轨迹也有详细记录。然而,人们对患者的长期症状体验知之甚少。本研究旨在了解B细胞淋巴瘤CAR T细胞治疗后缓解期成年患者的症状体验:研究采用定性描述设计,并进行主题分析。研究人员在一家三级学术医疗中心进行招募,招募标准如下:在入组前3至12个月期间接受过CAR T细胞疗法治疗B细胞淋巴瘤,且目前处于缓解期的成年患者。研究小组进行了半结构化访谈,对访谈记录进行了归纳编码,小组成员每周举行一次会议,以确保访谈的严谨性。最终样本包括 10 名患者:7名患者接受了替沙根利昔单抗治疗,3名患者接受了利索卡巴替尼单抗治疗,中位数为输液后169天,年龄为65岁:参试者继续报告了各种症状,包括疲劳、神经病变、耐力低下、失眠、记忆问题和疼痛。随着时间的推移,大多数症状都有所改善。一些症状干扰了社交活动、工作、驾驶和体力活动,但参与者表示大多数症状在接受 CAR T 细胞疗法之前就已存在,总体而言,他们认为 CAR T 细胞疗法是可以接受的:护理实践的启示:接受 CAR T 细胞治疗后病情缓解的患者通常会继续出现症状。护士应继续评估这一不断增长的患者群体,并确定患者是否需要额外的症状管理或支持。需要进一步开展研究,以了解长期症状轨迹以及与之前治疗方案和 CAR T 细胞疗法的关联。
{"title":"The Patient Symptom Experience After Tisagenlecleucel and Lisocabtagene Maraleucel CAR T-Cell Therapy for Lymphoma","authors":"Lucy Andersen ,&nbsp;Kayla M. Baker ,&nbsp;Heather Difilippo ,&nbsp;Salimah H. Meghani ,&nbsp;David Porter ,&nbsp;Jie Deng","doi":"10.1016/j.soncn.2024.151614","DOIUrl":"10.1016/j.soncn.2024.151614","url":null,"abstract":"<div><h3>Objectives</h3><p>Chimeric Antigen Receptor (CAR) T-cell treatment is associated with several unique toxicities, and the short-term symptom trajectory in the immediately after therapy is well-documented. However, little is known about patients’ long-term symptom experience. The study aimed to elicit the symptom experience of adult patients in remission after CAR T-cell therapy for B cell lymphoma.</p></div><div><h3>Data Sources</h3><p>A qualitative descriptive design with thematic analysis was utilized. Recruitment occurred at a tertiary academic medical center using the following inclusion criteria: adult recipient of CAR T-cell therapy for B-cell lymphoma between 3 and 12 months prior to enrollment, and currently in remission. Semi-structured interviews were conducted, transcripts were inductively coded, and team members met weekly to ensure rigor. The final sample included 10 patients: Seven received tisagenlecleucel and three received lisocabtagene marleucel and were a median of 169 days post-infusion and 65 years of age.</p></div><div><h3>Conclusions</h3><p>Participants continued to report symptoms, including fatigue, neuropathy, low endurance, insomnia, memory problems, and pain. Most symptoms improved over time. Some symptoms interfered with social activities, work, driving, and physical activity, though participants reported that most symptoms existed prior to CAR T-cell therapy, and overall, found CAR T-cell therapy acceptable.</p></div><div><h3>Implications for Nursing Practice</h3><p>Patients in remission after CAR T-cell therapy often continue to experience symptoms. Nurses should continue to assess this growing patient population and determine if patients require additional symptom management or support. Further research is needed to understand long-term symptom trajectory and associations with prior lines of therapy and CAR T-cell therapy.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140040846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influences Shaping Clinicians’ Monoclonal Antibody and Immune Checkpoint Inhibitor Preparation and Administration Management Practices: A Systematic Review 影响临床医生单克隆抗体和免疫检查点抑制剂制备与管理实践的因素:系统回顾。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151583
Angela Ballard , Carla Thamm , Theodora Ogle , Jane L. Phillips

Objectives

In 30 years, monoclonal antibodies (mAbs) and immune checkpoint inhibitors (ICPIs) have enhanced cancer survival and quality of life. Limited knowledge exists regarding the long-term risks of repeated exposure, especially for cancer nurses, who prepare and administer them. This systematic review aimed to identify influences shaping clinicians' awareness and practices in the safe preparation and administration of mAbs and ICPIs.

Data Sources

This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The databases CINAHL, EMBASE, Joanna Briggs Institute, OVID, MEDLINE, and Cochrane were searched. Eligibility and risk of bias were assessed by four reviewers.

Results

Of 7301 identified studies, 481 duplicates were removed, and 6673 were excluded after title and abstract review. A full-text review was conducted on 147 studies; six studies were included. A narrative synthesis generated two themes: (1) ambiguity contributes to variation in handling practices and (2) continuing professional development (CPD) is vital but hard to implement without evidence.

Conclusion

Lack of evidence regarding long-term risks and consensus creates uncertainty about the hazardous nature of unconjugated mAbs and ICPIs. Resulting in varied risk reduction strategies during preparation and administration, and inconsistent CPD. Protecting the long-term health of clinicians necessitates consensus on risk reduction strategies. This will be challenging without compelling evidence or international agreement on their hazardous classification.

Implications for Nursing Practice

In nursing, policy gaps and inconsistent CPD related to unconjugated mAbs and ICPIs may expose nurses to risks. Understanding the educational needs of nurses and global standardized guidelines are urgently needed.

目的:30 年来,单克隆抗体 (mAbs) 和免疫检查点抑制剂 (ICPIs) 提高了癌症患者的生存率和生活质量。有关反复接触的长期风险的知识有限,尤其是对准备和使用这些药物的癌症护士而言。本系统性综述旨在确定影响临床医生安全配制和使用 mAbs 和 ICPIs 的意识和实践的因素:本系统综述遵循系统综述和荟萃分析首选报告项目(PRISMA)指南。检索了 CINAHL、EMBASE、Joanna Briggs Institute、OVID、MEDLINE 和 Cochrane 等数据库。由四位审稿人对资格和偏倚风险进行评估:在 7301 项已确定的研究中,481 项重复的研究被删除,6673 项研究在标题和摘要审查后被排除。对 147 项研究进行了全文综述,其中包括 6 项研究。叙述性综述产生了两个主题:(1)模糊性导致处理方法的差异;(2)持续专业发展(CPD)至关重要,但在没有证据的情况下难以实施:结论:缺乏有关长期风险和共识的证据,造成了未结合 mAbs 和 ICPIs 危险性的不确定性。结论:由于缺乏有关长期风险的证据和共识,导致人们对非结合 mAbs 和 ICPIs 的危害性质存在不确定性,从而导致在制备和用药过程中采取不同的降低风险策略,以及 CPD 不一致。要保护临床医生的长期健康,就必须就降低风险的策略达成共识。如果没有令人信服的证据或国际上对其危险性分类的一致意见,这将是一项挑战:在护理领域,与非结合 mAbs 和 ICPIs 相关的政策空白和不一致的 CPD 可能会使护士面临风险。迫切需要了解护士的教育需求和全球标准化指南。
{"title":"Influences Shaping Clinicians’ Monoclonal Antibody and Immune Checkpoint Inhibitor Preparation and Administration Management Practices: A Systematic Review","authors":"Angela Ballard ,&nbsp;Carla Thamm ,&nbsp;Theodora Ogle ,&nbsp;Jane L. Phillips","doi":"10.1016/j.soncn.2024.151583","DOIUrl":"10.1016/j.soncn.2024.151583","url":null,"abstract":"<div><h3>Objectives</h3><p>In 30 years, monoclonal antibodies (mAbs) and immune checkpoint inhibitors (ICPIs) have enhanced cancer survival and quality of life. Limited knowledge exists regarding the long-term risks of repeated exposure, especially for cancer nurses, who prepare and administer them. This systematic review aimed to identify influences shaping clinicians' awareness and practices in the safe preparation and administration of mAbs and ICPIs.</p></div><div><h3>Data Sources</h3><p>This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The databases CINAHL, EMBASE, Joanna Briggs Institute, OVID, MEDLINE, and Cochrane were searched. Eligibility and risk of bias were assessed by four reviewers.</p></div><div><h3>Results</h3><p>Of 7301 identified studies, 481 duplicates were removed, and 6673 were excluded after title and abstract review. A full-text review was conducted on 147 studies; six studies were included. A narrative synthesis generated two themes: (1) ambiguity contributes to variation in handling practices and (2) continuing professional development (CPD) is vital but hard to implement without evidence.</p></div><div><h3>Conclusion</h3><p>Lack of evidence regarding long-term risks and consensus creates uncertainty about the hazardous nature of unconjugated mAbs and ICPIs. Resulting in varied risk reduction strategies during preparation and administration, and inconsistent CPD. Protecting the long-term health of clinicians necessitates consensus on risk reduction strategies. This will be challenging without compelling evidence or international agreement on their hazardous classification.</p></div><div><h3>Implications for Nursing Practice</h3><p>In nursing, policy gaps and inconsistent CPD related to unconjugated mAbs and ICPIs may expose nurses to risks. Understanding the educational needs of nurses and global standardized guidelines are urgently needed.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0749208124000044/pdfft?md5=42a680dd14a67d12a701daa792df0fa8&pid=1-s2.0-S0749208124000044-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139713337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transitional Care Navigation 过渡护理导航。
IF 2.2 4区 医学 Q1 Nursing Pub Date : 2024-04-01 DOI: 10.1016/j.soncn.2024.151580
Anna Liza Rodriguez , Lauren Cappelletti , Sherry M. Kurian , Christina Passio , Susan Rux

Objectives

This manuscript aims to provide an extensive review of the literature, synthesize findings, and present substantial insights on the current state of transitional care navigation. Additionally, the existing models of care, pertaining to the concept and approach to transitional care navigation, will be highlighted.

Methods

An extensive search was conducted though using multiple search engines, topic-specific key terminology, eligibility of studies, as well as a limitation to only literature of existing relevance. Integrity of the evidence was established through a literature review matrix source document. A synthesis of nursing literature from organizations and professional publications was used to generate a comparison among various sources of evidence for this manuscript. Primary evidence sources consisted of peer-reviewed journals and publications from professional organizations such as the AHRQ, Academic Search Premier, CINAHL Plus with Full Text, and the Talbot research library.

Results

A total of five systematic reviews (four with meta-analysis) published between 2016 and 2022 and conducted in several countries (Brazil, Korea, Singapore, and the US) were included in this review. A combined total of 105 studies were included in the systematic reviews with 53 studies included in meta-analyses. The review of the systematic reviews identified three overarching themes: care coordination, care transition, and patient navigation. Care coordination was associated with an increase in care quality rating, increased the health-related quality of life in newly diagnosed patients, reduced hospitalization rates, reduced emergency department visits, timeliness in care, and increased appropriateness of healthcare utilization. Transitional care interventions resulted to reduced average number of admissions in the intervention (I) group vs control (C) (I = 0.75, C = 1.02) 180 days after a 60-day intervention, reduced readmissions at 6 months, and reduced average number of visits 180 days after 60-day intervention (I = 2.79, C = 3.60). Nurse navigators significantly improved the timeliness of care from cancer screening to first-course treatment visit (MD = 20.42, CI = 8.74 to 32.10, P = .001).

Conclusion

The care of the cancer patient entails treatments, therapies, and follow-up care outside of the hospital setting. These transitions can be challenging as they require coordination and collaboration among various health care sites. The attributes of transitional care navigation overlap with care coordination, care transition, and patient navigation. There is an opportunity to formally develop a transitional care navigation model to effectively addresses the challenges in care transitions for patient including barriers to health profession

目的:本手稿旨在对文献进行广泛综述,对研究结果进行归纳总结,并就过渡性护理导航的现状提出实质性见解。此外,还将重点介绍与过渡性护理导航的概念和方法有关的现有护理模式:通过使用多个搜索引擎、特定主题的关键术语、研究资格以及只限于现有相关文献等方法进行了广泛的搜索。通过文献综述矩阵源文件确定证据的完整性。本手稿综合了各组织和专业出版物中的护理文献,对各种证据来源进行了比较。主要证据来源包括同行评审期刊和专业组织的出版物,如 AHRQ、Academic Search Premier、CINAHL Plus with Full Text 和 Talbot 研究图书馆:本综述共纳入了 2016 年至 2022 年间发表的五篇系统综述(其中四篇进行了荟萃分析),这些综述是在多个国家(巴西、韩国、新加坡和美国)进行的。系统综述共纳入 105 项研究,荟萃分析共纳入 53 项研究。对系统综述的审查确定了三大主题:护理协调、护理过渡和患者指导。护理协调与护理质量评分的提高、新诊断患者与健康相关的生活质量的提高、住院率的降低、急诊就诊率的降低、护理的及时性以及医疗保健利用的合理性的提高有关。过渡护理干预措施使干预组(I)与对照组(C)在 60 天干预 180 天后的平均入院次数减少(I = 0.75,C = 1.02),6 个月后的再入院次数减少,60 天干预 180 天后的平均就诊次数减少(I = 2.79,C = 3.60)。护士导航员大大提高了从癌症筛查到首次治疗就诊的及时性(MD = 20.42,CI = 8.74 到 32.10,P = .001):癌症患者的护理包括医院外的治疗、疗法和后续护理。这些过渡过程需要不同医疗机构之间的协调与合作,因此极具挑战性。过渡性护理导航的属性与护理协调、护理过渡和患者导航重叠。我们有机会正式开发一种过渡性护理导航模式,以有效解决病人在护理过渡过程中遇到的挑战,包括医疗专业人员在不同护理机构之间交流信息或沟通的障碍,以及护理机构之间协调的复杂性。美国国家癌症研究所(NCI)指定的一家独立综合癌症中心开发的过渡性护理导航和诊所模式是一种多学科方法,旨在缩小从医院到家庭的护理差距:过渡性护理导航模式旨在将现有的出院和向家庭或急性期后护理环境过渡这两个单独过程的观点和视角转变为一种集体护理方法。该模式支持提供优质、全面的连续性综合护理,帮助患者遵守治疗方案,加强对患者和护理人员的教育,改善健康状况。
{"title":"Transitional Care Navigation","authors":"Anna Liza Rodriguez ,&nbsp;Lauren Cappelletti ,&nbsp;Sherry M. Kurian ,&nbsp;Christina Passio ,&nbsp;Susan Rux","doi":"10.1016/j.soncn.2024.151580","DOIUrl":"10.1016/j.soncn.2024.151580","url":null,"abstract":"<div><h3>Objectives</h3><p>This manuscript aims to provide an extensive review of the literature, synthesize findings, and present substantial insights on the current state of transitional care navigation. Additionally, the existing models of care, pertaining to the concept and approach to transitional care navigation, will be highlighted.</p></div><div><h3>Methods</h3><p>An extensive search was conducted though using multiple search engines, topic-specific key terminology, eligibility of studies, as well as a limitation to only literature of existing relevance. Integrity of the evidence was established through a literature review<span> matrix source document. A synthesis of nursing literature from organizations and professional publications was used to generate a comparison among various sources of evidence for this manuscript. Primary evidence sources consisted of peer-reviewed journals and publications from professional organizations such as the AHRQ, Academic Search Premier, CINAHL Plus with Full Text, and the Talbot research library.</span></p></div><div><h3>Results</h3><p><span>A total of five systematic reviews<span><span> (four with meta-analysis) published between 2016 and 2022 and conducted in several countries (Brazil, Korea, Singapore, and the US) were included in this review. A combined total of 105 studies were included in the systematic reviews<span> with 53 studies included in meta-analyses. The review of the systematic reviews identified three overarching themes: care coordination, care transition, and patient navigation. Care coordination was associated with an increase in care quality rating, increased the health-related quality of life in newly diagnosed patients, reduced hospitalization rates, reduced </span></span>emergency department<span><span><span> visits, timeliness in care, and increased appropriateness of healthcare utilization. Transitional care interventions resulted to reduced average number of admissions in the intervention (I) group vs control (C) (I = 0.75, C = 1.02) 180 days after a 60-day intervention, reduced </span>readmissions at 6 months, and reduced average number of visits 180 days after 60-day intervention (I = 2.79, C = 3.60). Nurse navigators significantly improved the timeliness of care from </span>cancer screening<span> to first-course treatment visit (MD = 20.42, CI = 8.74 to 32.10, </span></span></span></span><em>P</em> = .001).</p></div><div><h3>Conclusion</h3><p>The care of the cancer patient entails treatments, therapies, and follow-up care outside of the hospital setting. These transitions can be challenging as they require coordination and collaboration among various health care sites. The attributes of transitional care navigation overlap with care coordination, care transition, and patient navigation. There is an opportunity to formally develop a transitional care navigation model to effectively addresses the challenges in care transitions for patient including barriers to health profession","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139643363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Seminars in Oncology Nursing
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