Seminars in Oncology Nursing最新文献

{"title":"Advanced Practice Nurses and Their Roles in Swiss Cancer Care: A Cross-Sectional Study","authors":"Franziska Geese ,&nbsp;Denise Bryant-Lukosius ,&nbsp;Sandra Zwakhalen ,&nbsp;Sabine Hahn","doi":"10.1016/j.soncn.2024.151626","DOIUrl":"10.1016/j.soncn.2024.151626","url":null,"abstract":"<div><h3>Objectives</h3><p>To examine the advanced practice nurse workforce in Swiss cancer care and how their roles are being implemented (eg, role structures, processes) to achieve optimal outcomes for patients and their families, care organizations, and the broader health care system.</p></div><div><h3>Methods</h3><p>A cross-sectional study was conducted. The sample included master-prepared advanced practice nurses in cancer care, who completed an online questionnaire from December 2021 to January 2022. Thirty-nine items assessed structures (eg, role characteristics, utilization), processes (eg, role activities, interventions), and perceived outcomes (eg, for patients, the health care system) of advanced practice nurses in Swiss cancer care. Data from closed questions were analyzed using descriptive statistics. Data from open-ended questions were organized and summarized into categories related to domains of advanced practice nursing and its reported frequency by the advanced practice nurses.</p></div><div><h3>Results</h3><p>The participating advanced practice nurses (n = 53), worked in half of the 26 Swiss cantons. Interventions were identified within nine categories, of which most were targeted to patients and their families (n = 7), followed by health care professionals (n = 2). Perceived positive outcomes were patient symptom management, length of hospital stay, and health care costs. Participants felt less confident in cancer care (eg, autonomous practice) and reported 15 professional development needs (eg, medical interventions, teaching).</p></div><div><h3>Conclusions</h3><p>This study provides a comprehensive examination of 53 advanced practice nurses, detailing the characteristics of their roles and utilization across various jurisdictions and health care settings. The results highlight the diverse dimensions of advanced practice nursing and its potential to enhance cancer services and outcomes in Switzerland. Opportunities for role development support and expansion are identified.</p></div><div><h3>Implications for Nursing Practice</h3><p>More systematic health human resource planning is needed to expand the deployment of advanced practice nurses across jurisdictions, practice settings, and more diverse patient populations. Role development needs show the desire for specialized educational preparation in cancer care.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0749208124000652/pdfft?md5=269e9a3a0c4433e8525d778192ac8927&pid=1-s2.0-S0749208124000652-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140629293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Future-Oriented Perspective on Advanced Practice Nursing Roles in Cancer Care: Pushing the Boundaries to Promote Innovation and Achieve Equitable, Patient-Centered Care","authors":"Denise Bryant-Lukosius ,&nbsp;Eva Pape ,&nbsp;Maura Dowling","doi":"10.1016/j.soncn.2024.151635","DOIUrl":"10.1016/j.soncn.2024.151635","url":null,"abstract":"","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140769963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing Considerations for Cytokine Release Syndrome in Relapsed/Refractory Multiple Myeloma: Experience with Teclistamab from the MajesTEC-1 Study","authors":"Donna Catamero ,&nbsp;Patricia Blázquez Benito ,&nbsp;Samantha Shenoy ,&nbsp;Margaret Doyle ,&nbsp;Jessica Fowler ,&nbsp;Rachel Kobos ,&nbsp;Arnob Banerjee ,&nbsp;Sandy Kruyswijk","doi":"10.1016/j.soncn.2024.151621","DOIUrl":"10.1016/j.soncn.2024.151621","url":null,"abstract":"<div><h3>Objectives</h3><p>Cytokine release syndrome (CRS) is a systemic inflammatory response that is commonly observed as a class effect of T-cell–redirecting therapies. This article provides important practical guidance for nurses relating to the diagnosis, monitoring, and management of CRS in patients receiving teclistamab, based on experience from the MajesTEC-1 clinical trial and real-life nursing practice.</p></div><div><h3>Methods</h3><p>MajesTEC-1 is a phase 1/2 study of teclistamab in heavily pretreated patients with relapsed/refractory multiple myeloma. To mitigate the risk of high-grade CRS, patients were carefully monitored for early signs and symptoms of CRS (including fever, which must have fully resolved before teclistamab administration).</p></div><div><h3>Results</h3><p>A survey of nurses from several of the study sites provided additional real-life insights into nursing best practices for managing CRS from four academic institutions in three countries.</p></div><div><h3>Conclusions</h3><p>In MajesTEC-1, 72% of patients treated with teclistamab experienced CRS, the majority of which was low grade. All cases resolved and none led to treatment discontinuation. Real-life supportive measures for CRS are generally aligned with those outlined in the study.</p></div><div><h3>Implications for Nursing Practice</h3><p>Because nurses are on the frontline of patient care, they play a crucial role in promptly recognizing the signs and symptoms of CRS and responding with timely and appropriate supportive treatment. This review provides important practical guidance for nurses on diagnosis, monitoring, and management of CRS in patients receiving teclistamab, based on experience from the MajesTEC-1 trial and real-life nursing practice.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0749208124000603/pdfft?md5=3b8e7a4c37b6d9a8f4c28eda0e94269f&pid=1-s2.0-S0749208124000603-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140792433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching-Learning Programs to Prevent and Control Infections Related to Long-Term Central Venous Access Device in Cancer Patients: A Systematic Review","authors":"Leticia Genova Vieira ,&nbsp;Guilherme Schneider ,&nbsp;Amanda Salles Margatho ,&nbsp;Fernanda Titareli Merizio Martins Braga ,&nbsp;Christiane Inocêncio Vasques ,&nbsp;Tom Møller ,&nbsp;Elaine Barros Ferreira ,&nbsp;Renata Cristina de Campos Pereira Silveira","doi":"10.1016/j.soncn.2024.151650","DOIUrl":"10.1016/j.soncn.2024.151650","url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate the effectiveness of teaching-learning programs for cancer patients and/or their caregivers or family in preventing and controlling infections associated with long-term central venous access devices.</p></div><div><h3>Data Sources</h3><p>This systematic review used the CINAHL, Cochrane Library, EMBASE, LILACS, and MEDLINE via PubMed portal, Scopus, and Web of Science. Google Scholar was used for the gray literature search. The included studies were analyzed, and the obtained data were qualitatively synthesized. The risk of bias was assessed using Cochrane tools: RoB 2 and ROBINS-I. The certainty of the evidence was evaluated using the GRADE. The review protocol was registered in PROSPERO (CRD42021267530).</p></div><div><h3>Conclusion</h3><p>The teaching-learning programs were implemented through theoretical-practical and theoretical dimensions in five and two studies, respectively. The risk of bias in the studies was low, moderate, severe, and high in one, three, two, and one of them, respectively. The certainty was very low. Teaching-learning programs on central venous access devices care for cancer patients and/or their caregivers or families could be effective in reducing infection rates.</p></div><div><h3>Implications for Nursing Practice</h3><p>This systematic review addressed the teaching-learning programs for preventing and controlling infections associated with long-term central venous access devices. We identified that the most programs were effective in reducing the infection rates. The results may influence the clinical practice of oncology nurses, and consequently, the educational strategies and methods provided not only to these patients but for caregivers and families.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Central and Bridge Symptoms in Patients with Lung Cancer: A Network Analysis","authors":"Yuanyuan Luo ,&nbsp;Jiahui Luo ,&nbsp;Qing Su ,&nbsp;Zhihui Yang ,&nbsp;Jingxia Miao ,&nbsp;Lili Zhang","doi":"10.1016/j.soncn.2024.151651","DOIUrl":"10.1016/j.soncn.2024.151651","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to identify symptom clusters in lung cancer patients undergoing chemotherapy and the central and bridge symptoms within each symptom cluster.</p></div><div><h3>Methods</h3><p>In this cross-sectional study, 1,255 patients with lung cancer were recruited through convenience sampling at Nanfang Hospital. Patient symptom burden was assessed using the M.D. Anderson Symptom Inventory (MDASI) and the Lung Cancer module of the MDASI (MDASI-LC). Symptom clusters were identified using the Walktrap algorithm, and central and bridge symptoms in the symptom clusters were identified by network analysis.</p></div><div><h3>Results</h3><p>The patients included 818 (65.18%) males and 437 (34.82%) females with a mean age of 56.56 ± 11.78 years. Four symptom clusters were identified: fatigue, gastrointestinal, psychoneurological and respiratory. Their central symptoms were fatigue, vomiting, distress and hemoptysis, respectively, and their bridge symptoms were pain, vomiting, dry mouth and shortness of breath.</p></div><div><h3>Conclusions</h3><p>Lung cancer symptoms show certain strong correlations with each other, resulting in symptom clusters. Central symptoms may influence other symptoms within a symptom cluster, and bridge symptoms might impact the density of the symptom network. This study identified central and bridge symptoms in lung cancer patients undergoing chemotherapy. Targeting these symptoms with interventions for symptom clusters could make symptom management more precise and effective.</p></div><div><h3>Implications for Nursing Practice</h3><p>In clinical settings, the burden of symptom clusters may be reduced by intervening against the central symptoms of these symptom clusters. Alternatively, if the objective is to diminish the connections between different symptom clusters and holistically alleviate the overall burden, interventions focused on bridge symptoms may be employed.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0749208124000998/pdfft?md5=0f104d5bc2b050734d71125a26f15062&pid=1-s2.0-S0749208124000998-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced Practice Nursing and CAR-T Cell Therapy: Opportunities, Challenges and Future Directions","authors":"Daniel Kisielewski ,&nbsp;Matthias Naegele","doi":"10.1016/j.soncn.2024.151628","DOIUrl":"10.1016/j.soncn.2024.151628","url":null,"abstract":"<div><h3>Objectives</h3><p>Chimeric antigen receptor (CAR)-T cell therapy is a new treatment for patients with myeloma and other B cell malignancies where advanced practice nurses (APN) can make a great contribution. The aim of this review is to identify key aspects of current literature relevant to APNs working with this population.</p></div><div><h3>Methods</h3><p>Discussion of selected peer-reviewed literature and best practice guidelines found through electronic database searches (CINAHL, MEDLINE).</p></div><div><h3>Results</h3><p>Although few APN roles in CAR-T cell therapy have been published to date, recent research suggests that the APN is central to the care of these patients. They are essential for continuity of care and navigation through the treatment process, providing an important and consistent point of contact for patients’ and carers’ anxieties and uncertainties. APNs play a central role in symptom management, as they constantly incorporate new experience and scientific findings into the refinement of existing protocols. The continuum of care extends far beyond the inpatient stay and addresses symptoms that may persist long after cytokine release syndrome and neurotoxicity have resolved. The APN may therefore make a relevant contribution to patients’ health-related quality of life, given its likely correlation with the dynamics and intensity of treatment-related symptoms. The APN also takes on a leadership role in the treatment team.</p></div><div><h3>Conclusions</h3><p>APNs use all core competencies to sustainably support and empower patients and caregivers. This is achieved through counseling and education, in addition to identifying, developing, and implementing evidence-based symptom management. They play pivotal roles in introducing new CAR-T cell products, educating teams, and advancing their role through APN networks. Finally, APNs are integral members of multiprofessional teams, supporting colleagues in ethically challenging patient situations.</p></div><div><h3>Implications for Nursing Practice</h3><p>APNs in the field of CAR-T cell therapy make an important contribution to the continuous care of patients, caregivers, and treatment teams.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140779639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer Screening and Prevention in the Transgender and Gender Diverse Population: Considerations and Strategies for Advanced Practice Nurses","authors":"Erin Ziegler ,&nbsp;Toni Slotnes-O'Brien ,&nbsp;Micah D.J. Peters","doi":"10.1016/j.soncn.2024.151630","DOIUrl":"10.1016/j.soncn.2024.151630","url":null,"abstract":"<div><h3>Objectives</h3><p>This discussion paper presents recent evidence regarding cancer screening and prevention among the transgender and gender diverse (TGD) community and highlights where and how advanced practice nurses (APNs), particularly those in primary care, can better contribute to closing the gap between healthcare disparities between TGD and cisgendered populations.</p></div><div><h3>Methods</h3><p>Relevant publications on the topic and professional guidelines and evidence have formed the basis for this discussion paper.</p></div><div><h3>Results</h3><p>TGD individuals are a vulnerable population with unique needs. They remain at risk of cancer and might be at greater risk of developing some cancers compared to cisgendered people but are underscreened. Barriers to gender-affirming care need to be addressed to improve access to prevention and screening services and improve the cancer care experiences and outcomes of TGD people.</p></div><div><h3>Conclusion</h3><p>APNs can work in collaboration with TGD individuals and the healthcare system to improve access to culturally safe cancer screening and more effective prevention of cancer and poor cancer outcomes.</p></div><div><h3>Implications for Nursing Practice</h3><p>APNs have the potential to improve access to cancer screening for TGD people by increasing their understanding of the needs of the population, providing culturally safe care, and advocating for more preventative care and cancer screening. With greater knowledge and understanding of the needs and preferences of TGD people both broadly and in relation to cancer screening and prevention, targeted interventions and care approaches can be implemented. APNs should also aim to conduct evaluations and research into cancer prevention and screening to build the currently limited evidence base and nursing knowledge in this important field.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S074920812400069X/pdfft?md5=3dfe732e7fb35f8c6d308408889440cd&pid=1-s2.0-S074920812400069X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140788664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hereditary Cancer Syndrome Carriers: Feeling Left in the Corner","authors":"Celia Diez de los Rios de la Serna ,&nbsp;Maria Teresa Lluch-Canut ,&nbsp;Maria Paz Fernández-Ortega","doi":"10.1016/j.soncn.2024.151624","DOIUrl":"10.1016/j.soncn.2024.151624","url":null,"abstract":"<div><h3>Objectives</h3><p>There is limited evidence on health promotion interventions in people with hereditary cancer syndromes or on their main sources of support and information. This study aimed to understand these patients’ experiences and needs, including their information needs, their views on prevention and mental health, and the support they want from nurses.</p></div><div><h3>Methods</h3><p>This qualitative study included 22 people (8 previvors and 14 survivors) with hereditary breast and ovarian syndrome or Lynch syndrome from 10 European countries. Participants underwent individual semi-structured interviews, which were recorded and transcribed for reflexive thematic analysis. The patient and public involvement panel provided input on study design and thematic analysis.</p></div><div><h3>Results</h3><p>Patient experiences were similar regardless of the country and access to testing and screening. Participants reported receiving little information on the importance of health behaviors for cancer risk and expressed their wish to be followed by cancer professionals. They felt compelled to seek support and information from the internet and patient groups. The main themes identified were: (unmet) informational and support needs, seeing life in a different way, and limitations of health care providers.</p></div><div><h3>Conclusions</h3><p>People with hereditary cancer syndromes need professionals to be involved in their long-term management and to provide reliable information. As genomics are increasingly integrated in oncology, the need for professionals to support these populations will increase.</p></div><div><h3>Implications for Nursing Practice</h3><p>Nurses are crucial for promoting self-management and advocating for patient decision-making; however, they need skills and knowledge to do so. There is a need for nurses to get more involved in understanding hereditary cancer syndromes and an opportunity to take the lead in the care of these people.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0749208124000639/pdfft?md5=0f6437cca9cf2ab40d93300ac65b2288&pid=1-s2.0-S0749208124000639-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140765208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Pilot Study of a Family Management Program for Parents of Children with Acute Lymphoblastic Leukemia","authors":"Wachareekorn Aungkaprasatchai ,&nbsp;Nujjaree Chaimongkol ,&nbsp;Pornpat Hengudomsub ,&nbsp;Verna L. Hendricks-Ferguson","doi":"10.1016/j.soncn.2024.151648","DOIUrl":"10.1016/j.soncn.2024.151648","url":null,"abstract":"<div><h3>Objectives</h3><p>The aim of this completed pilot study was to evaluate the feasibility of implementing a family management program (FMP) for parents of children with acute lymphoblastic leukemia (ALL).</p></div><div><h3>Data Sources</h3><p>A convenience sample of 11 parents of preschool-aged children with ALL were recruited from an ambulatory chemotherapy-care clinic at a tertiary hospital in Thailand. Participants received three FMP sessions over 3 weeks. The FMP is based on two established family programs (ie, FMP-style framework and building on family strengths) and reviewed literature. The following measures were used to evaluate parents’ responses at baseline, postintervention, and follow-up: Family Management Measure, Beach-Center Family Quality-of-Life Scale, and Pediatric Quality of Life Inventory. Data were analyzed using one-way repeated-measures analysis of variance.</p></div><div><h3>Conclusion</h3><p>The study results provide promising evidence that the FMP is feasible and improves family management and quality of life for parents of enrolled children with ALL.</p></div><div><h3>Implications for Nursing Practice</h3><p>Educating pediatric oncology nurses and other healthcare professionals to replicate the FMP may help to provide better family management, and child quality of life support to future parents and other family members of young children diagnosed with ALL. This support should focus on educating parents about the potential effects of caring for a child with ALL on the family and fostering positive relationships within the family and offering guidance on effective family communications and decision-making processes.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensional Model of Energy in Patients With Cancer","authors":"David Ayangba Asakitogum ,&nbsp;Jerry John Nutor ,&nbsp;Rachel Pozzar ,&nbsp;Marilyn Hammer ,&nbsp;Sarah Alismail ,&nbsp;Kord M. Kober ,&nbsp;Christine Miaskowski","doi":"10.1016/j.soncn.2024.151644","DOIUrl":"10.1016/j.soncn.2024.151644","url":null,"abstract":"<div><h3>Objectives</h3><p>Evidence suggests that energy is a distinct symptom from fatigue in patients with cancer. The purpose of this paper is to present the Multidimensional Model of Energy in Patients with Cancer (MMEPC) that is based on emerging evidence and to make recommendations for clinical practice and future research.</p></div><div><h3>Methods</h3><p>The literature was reviewed to determine various factors associated with variations in energy in patients with cancer. In addition, some of the emerging evidence in the model is supported by studies of energy in the general population and in patients with other chronic conditions.</p></div><div><h3>Results</h3><p>Based on a review of the literature, specific concepts in the MMEPC include: person factors, clinical factors, cancer-related factors, biological factors, factors associated with energy balance, and co-occurring symptoms. The evidence to support the association between each of these factors and variations in energy levels in patients with cancer is described and synthesized.</p></div><div><h3>Conclusion</h3><p>This article provides emerging evidence on factors that influence variations in energy levels in patients with cancer. While the fundamental biobehavioral and biologic mechanisms that underlie variations in energy levels are not well understood, the model can be used to design pre-clinical and clinical studies of energy in patients with cancer. In addition, while emerging evidence supports the hypothesis that fatigue and energy are distinct symptoms, additional research on common and distinct risk factors and underlying mechanisms is warranted to be able to develop and test precision interventions for one or both symptoms.</p></div><div><h3>Implications for Nursing Practice</h3><p>The risk factors (eg, being female, sleep quality) associated with variations in energy levels in patients with cancer identified in this paper have important clinical implications. Clinicians can use the identified risk factors to guide their assessments; identify high-risk patients with decrements in energy decrement; and develop targeted energy conservation interventions for the patients.</p></div>","PeriodicalId":54253,"journal":{"name":"Seminars in Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0749208124000913/pdfft?md5=13fb171df3184441e70c60613a684aa9&pid=1-s2.0-S0749208124000913-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}