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Maillard reaction-based conjugates as carrier strategies for delivery of bioactive compounds: A review 基于美拉德反应的缀合物作为递送生物活性化合物的载体策略:综述
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-02-01 Epub Date: 2024-12-10 DOI: 10.1016/j.cofs.2024.101260
Yumeng Zhang, Yuanfang Xie, Junhua Shao, Xiqing Yue, Mohan Li
Bioactive compounds (BCs) have long been hindered by multiple barriers in the gastrointestinal tract (GIT) preventing effective absorption. Thus, in order to further enhance the bioavailability of BCs, delivery systems consisting of conjugates using the Maillard reaction as carriers are gradually coming into the limelight. Since BCs are challenging for delivery in GIT, the delivery and release of BCs in this review will be updated and discussed based on the carriers of the Maillard conjugates. The focus includes emulsions, nanoparticles, microcapsules, gels, liposomes, and solid lipid nanoparticles. Upon this, the application of Maillard conjugates offers the possibility of targeted release of BCs in vivo and their protection. This review offers insights into delivery systems designed that improve bioavailability.
长期以来,生物活性化合物(bc)一直受到胃肠道(GIT)多种屏障的阻碍,无法有效吸收。因此,为了进一步提高bc的生物利用度,以美拉德反应为载体的缀合物组成的递送系统逐渐成为人们关注的焦点。由于BCs在GIT中的交付具有挑战性,因此本文将根据美拉德共轭物的载体更新和讨论BCs的交付和发布。重点包括乳液,纳米颗粒,微胶囊,凝胶,脂质体和固体脂质纳米颗粒。在此基础上,美拉德偶联物的应用提供了在体内靶向释放bc及其保护的可能性。这篇综述为提高生物利用度的给药系统设计提供了见解。
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引用次数: 0
Advancements in nucleic acid–based enumeration methods for viable foodborne pathogenic bacteria 基于核酸的食源性致病菌活菌计数方法研究进展
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.1016/j.cofs.2024.101254
Chi Song , Yangtai Liu , Ruihua Ding , Hongzhi Zhang , Shilun Feng
Foodborne diseases caused by pathogenic bacteria present a significant public health concern. The efficient and accurate identification and quantification of viable bacteria is crucial for preventing and mitigating disease outbreaks. This review summarizes the current status and recent advancements in enumeration methods for viable foodborne pathogenic bacteria. Special emphasis is placed on nucleic acid–based quantitative detection methods, including direct RNA-based detection and preprocessed DNA detection. The quantitative detection methods for viable bacteria are advancing to become more rapid, sensitive, robust, and automated. Nucleic acid–based enumeration methods may be the foundation of the next-generation quantitative microbiological risk analysis and play a pivotal role in the field of food safety.
由致病菌引起的食源性疾病是一个重大的公共卫生问题。有效、准确地鉴定和定量活菌对预防和减轻疾病暴发至关重要。本文综述了食源性致病菌活菌计数方法的研究现状及最新进展。特别强调以核酸为基础的定量检测方法,包括直接rna检测和预处理DNA检测。活菌的定量检测方法正朝着快速、灵敏、可靠和自动化的方向发展。基于核酸的枚举方法可能是下一代定量微生物风险分析的基础,在食品安全领域发挥关键作用。
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引用次数: 0
Polysaccharide-based edible films — strategies to minimize water vapor permeability 以多糖为基础的可食用薄膜-减少水蒸气渗透性的策略
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-02-01 Epub Date: 2024-12-09 DOI: 10.1016/j.cofs.2024.101258
Lilah Saidi , Yong Wang , Peter R Wich , Cordelia Selomulya
With increasing focus on sustainability, there has been a growth in the development of edible films to improve food quality, particularly with polysaccharides, as they exhibit desirable properties, including functional diversity and efficient oxygen and carbon dioxide barriers. However, high water vapor permeability (WVP) still limits their applications as film material. While a number of studies have reported the WVP values of various polysaccharide-based films (PBFs), there is a lack of cohesive insights that could help formulate the approach to reduce WVP of these films. This review highlights reported strategies to reduce WVP in edible polysaccharide films, while comparing their efficacy, and discusses the role of relevant properties influencing WVP. Based on the current understanding, the addition of phenolic compounds has been identified as a promising pathway to reduce WVP. More research is required to potentially integrate several methods to reduce WVP, including with lipophilic nanoparticles.
随着对可持续性的日益关注,可食用薄膜的发展也在增长,以提高食品质量,特别是多糖,因为它们表现出令人满意的特性,包括功能多样性和有效的氧气和二氧化碳屏障。然而,高透气性仍然限制了其作为薄膜材料的应用。虽然许多研究已经报道了各种多糖基膜(pbf)的WVP值,但缺乏能够帮助制定降低这些膜WVP的方法的凝聚力见解。本文综述了已报道的降低可食性多糖膜WVP的策略,并对其效果进行了比较,并讨论了相关特性对WVP的影响。根据目前的认识,酚类化合物的添加已被确定为降低WVP的有希望的途径。需要更多的研究来潜在地整合几种方法来减少WVP,包括亲脂纳米颗粒。
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引用次数: 0
Precision fermentation for producing food ingredients 精密发酵生产食品配料
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-02-01 Epub Date: 2024-11-12 DOI: 10.1016/j.cofs.2024.101242
Sumin Cho , Seok Yeong Jung , Hyunmin Eun , Sang Yup Lee
Fermentation has been crucial in human history, evolving in meaning with advances in biotechnology. Advancements in synthetic biology and metabolic engineering have led to the emergence of precision fermentation, which involves using metabolically engineered microbes to produce functional ingredients from simple carbon sources under precisely controlled conditions. These technologies have the potential to develop sustainable platforms for producing food ingredients, which could help address food crisis issues. This review discusses how systems metabolic engineering can be applied to precision fermentation-based production of food ingredients in microbial hosts, with a particular focus on the production of flavoring and coloring agents. Additionally, the development of optimal downstream processing techniques for each product category is also examined.
发酵在人类历史上起着至关重要的作用,其意义随着生物技术的进步而不断演变。合成生物学和代谢工程的进步导致了精密发酵的出现,这涉及到在精确控制的条件下,利用代谢工程微生物从简单的碳源生产功能成分。这些技术有可能开发出可持续的食品原料生产平台,从而有助于解决粮食危机问题。本文讨论了如何将系统代谢工程应用于微生物宿主中基于精密发酵的食品配料生产,特别关注了调味剂和着色剂的生产。此外,还研究了每种产品类别的最佳下游加工技术的发展。
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引用次数: 0
Next-generation probiotics: innovations in safety assessments 新一代益生菌:安全评估的创新
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-02-01 Epub Date: 2024-11-08 DOI: 10.1016/j.cofs.2024.101238
Ziyan Hua , Shu Liu , Guang Yang , Xiaoyue Hou , Yaowei Fang
The human gut microbiota is integral to health and disease, fostering the development of next-generation probiotics (NGPs) tailored for specific health conditions. This review addresses the safety assessments and development of NGPs, highlighting recent biotechnological advances that enable the customization of NGPs for specific health conditions. It examines the methodologies for in vitro and in vivo animal model assessments focusing on potential toxicity. Additionally, we explore the integration of multi-omics, synthetic biology, and advanced computational technologies, including artificial intelligence and machine learning, to enhance the precision and safety of NGPs. Incorporating NGPs into food matrices represents an effective approach to delivering these probiotics and enhancing the health benefits of food products. This review underscores the necessity of adopting comprehensive safety assessments to navigate the complexities of NGP development effectively.
人类肠道微生物群与健康和疾病密不可分,这促进了针对特定健康状况的下一代益生菌(NGPs)的开发。本综述探讨了 NGPs 的安全性评估和开发,重点介绍了近期生物技术的进步,这些进步使得针对特定健康状况定制 NGPs 成为可能。它探讨了体外和体内动物模型评估的方法,重点关注潜在的毒性。此外,我们还探讨了多组学、合成生物学和先进计算技术(包括人工智能和机器学习)的整合,以提高 NGPs 的精确性和安全性。将 NGPs 添加到食品基质中是提供这些益生菌并提高食品健康益处的有效方法。本综述强调了采用全面安全评估以有效驾驭复杂的 NGP 开发的必要性。
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引用次数: 0
Comparison of fatty acid characteristics in human milk, bovine milk, and infant formula for better emulation 比较人乳、牛乳和婴儿配方奶粉中的脂肪酸特征,以便更好地模拟
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-02-01 Epub Date: 2024-11-08 DOI: 10.1016/j.cofs.2024.101240
Xue Yang , Lu Meng , Ashikur Rahman , Jiaqi Wang , Nan Zheng
Fatty acids (FAs) in human milk (HM) are essential for infant growth and development, particularly during the first six months of life. In infant formula (IF), FAs mainly originate from bovine milk (BM). However, comparative data on FA patterns and structures across HM, BM, and IF are limited. This review, analyzing 37 studies from 2018 to 2023, provides a comprehensive FA characteristic, highlighting their differences in macroscopic patterns and key structures. For detectable FAs, HM and BM exhibit more diverse FA species compared to IF. HM is richer in monounsaturated (MUFA) and polyunsaturated FAs (PUFA), while BM contains higher levels of saturated FAs (SFA), placing IF between the two. The content of MUFA (except for C18:1 c9, c20:1 c9) and PUFA (C18:2 n6, c18:2 c9 t11, c18:2 t10.c12, and c18:3 n3) in IF should be increased, and the content of SFA (C6:0, C8:0, C11:0, C12:0, C17:0) should be reduced in order to more closely simulate HM. The differences between HM and IF may be attributed to the use of BM as a base ingredient, mainly reflected in profile, structure, stability, and bioavailability. Despite the latest advancements, such as the addition of structural lipid 1,3-dioleoyl-2-palmitoylglycerol and milk fat globule membranes, fully replicating the complexity and functionality of HM FAs in IF remains challenging. Further investigation into these aspects could reveal new insights into how HM supports optimal infant health and development, providing the foundation for even more advanced IF formulations.
母乳中的脂肪酸(FAs)对婴儿的生长发育至关重要,尤其是在生命的头六个月。在婴儿配方奶粉(IF)中,FAs主要来源于牛乳(BM)。然而,在HM, BM和IF之间的FA模式和结构的比较数据是有限的。本文对2018年至2023年的37项研究进行了分析,提供了综合的FA特征,突出了它们在宏观模式和关键结构上的差异。对于可检测的FAs, HM和BM表现出比IF更多样化的FA种类。HM富含单不饱和脂肪酸(MUFA)和多不饱和脂肪酸(PUFA),而BM含有更高水平的饱和脂肪酸(SFA),将IF置于两者之间。MUFA(除C18:1 c9、c20:1 c9外)和PUFA (C18:2 n6、C18:2 c9 t11、C18:2 t10)的含量。增加IF中的c12和c18:3 n3),降低SFA (C6:0, C8:0, C11:0, c12:0, C17:0)的含量,以便更接近模拟HM。HM与IF的差异可能与BM作为基础成分的使用有关,主要体现在外形、结构、稳定性和生物利用度等方面。尽管有最新的进展,如添加结构脂质1,3-二油基-2-棕榈酰甘油和乳脂球膜,但在IF中完全复制HM FAs的复杂性和功能仍然具有挑战性。对这些方面的进一步调查可以揭示HM如何支持最佳婴儿健康和发育的新见解,为更先进的IF配方提供基础。
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引用次数: 0
Recent advances in Pickering emulsions for inhibiting foodborne bacteria 皮克林乳剂抑制食源性细菌的研究进展
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-02-01 Epub Date: 2024-12-17 DOI: 10.1016/j.cofs.2024.101265
Chuye Ji, Yixiang Wang
Foodborne bacteria pose significant risks to public health and economic conditions. Natural antibacterial agents have proven effective against foodborne bacterial contamination but often suffer from harsh environmental and processing conditions. Pickering emulsions, recognized for good stability, high loading capacity, sustained release, cost-effectiveness, low toxicity, biocompatibility, and sustainability, have emerged as efficient carriers for natural antibacterial agents and shown great promise in preserving fruits, vegetables, meats, seafood, and other foods by either direct coating or incorporation in active packaging films. With the growing interest in Pickering emulsions loaded with natural antibacterial agents, in this review, we highlight recent advances in their applications for inhibiting foodborne bacteria. The mostly investigated foodborne bacteria and the compositions and antibacterial mechanisms of natural antibacterial agents loaded Pickering emulsions are summarized, and food-related applications are spotlighted. Despite challenges, such as scalability and regulatory approval, antibacterial Pickering emulsions show great potential as sustainable preservatives for food preservation.
食源性细菌对公共卫生和经济状况构成重大风险。天然抗菌剂已被证明对食源性细菌污染有效,但往往受到恶劣的环境和加工条件的影响。酸洗乳剂因其良好的稳定性、高负载能力、持续释放、成本效益、低毒性、生物相容性和可持续性而被公认为天然抗菌剂的有效载体,并通过直接涂覆或结合在活性包装薄膜中,在保存水果、蔬菜、肉类、海鲜和其他食品方面显示出巨大的前景。随着人们对含有天然抗菌剂的皮克林乳剂越来越感兴趣,本文综述了其在抑制食源性细菌方面的最新进展。综述了目前研究较多的食源性细菌,以及含皮克林乳剂的天然抗菌剂的组成和抑菌机理,重点介绍了其在食品领域的应用。尽管存在可扩展性和监管批准等挑战,抗菌皮克林乳剂作为食品保鲜的可持续防腐剂显示出巨大的潜力。
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引用次数: 0
Microbial diversity and ecology of bottled water 瓶装水的微生物多样性和生态学
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-12-01 Epub Date: 2024-09-05 DOI: 10.1016/j.cofs.2024.101218
Danilo MV Boas, Oluwadara Alegbeleye, Anderson S Sant’Ana

This review article summarizes some studies that described alterations in microbial counts and diversity in bottled water products during postpackaging shelf life. It also discusses prevalent microbial groups recovered from bottled water samples in different parts of the world. Finally, it explores some of the advantages of contemporary microbial detection and characterization approaches, with a particular emphasis on implications for traceability and quality assurance in the food industry. Adequate understanding of the microbial ecology of bottled water can aid traceability for example, tracking the origin and quality of products throughout shelf life. Understanding the microbial diversity and factors that influence its changes through shelf life can meaningfully contribute to ensuring product integrity as well as consumer and public health safety.

这篇综述文章总结了一些描述瓶装水产品在包装后保质期内微生物数量和多样性变化的研究。文章还讨论了世界各地从瓶装水样本中发现的常见微生物群。最后,它探讨了当代微生物检测和表征方法的一些优势,特别强调了对食品行业可追溯性和质量保证的影响。充分了解瓶装水的微生物生态有助于溯源,例如在整个保质期内跟踪产品的来源和质量。了解微生物的多样性以及影响其在保质期内变化的因素,有助于确保产品的完整性以及消费者和公众的健康安全。
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引用次数: 0
The role of probiotic foods in acute pancreatitis: current status and future directions 益生菌食品在急性胰腺炎中的作用:现状与未来方向
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-12-01 Epub Date: 2024-10-22 DOI: 10.1016/j.cofs.2024.101231
Wenfei Qin , Guangqiang Wang , Yongjun Xia , Xin Song , Zhiqiang Xiong , Chunlan Huang , Chen Gong , Yue Zeng , Lianzhong Ai
Acute pancreatitis (AP) is a global disease with a complex pathogenesis, while the intestinal environment has been shown to be closely associated with the onset and progression of AP. Currently, probiotic foods have garnered increasing interest as a potential treatment for AP due to their ability to improve intestinal barrier function, maintain intestinal immunity, and modulate intestinal microbiome. This review summarizes research advances in probiotic foods applied in animal studies and clinical trials of AP management, including the strains, dosages, and durations in probiotic foods, and conclusion, and further discusses the potential mechanisms for probiotic foods in AP. Despite promising results, several limitations and unanswered questions remain, including the optimal probiotic strains, timing of intervention, and guideline for the components of probiotic foods. Future large-scale, multicenter randomized controlled trials are needed to elucidate the efficacy and mechanisms of probiotic foods in AP and address these current gaps in knowledge.
急性胰腺炎(AP)是一种发病机制复杂的全球性疾病,而肠道环境已被证明与急性胰腺炎的发病和进展密切相关。目前,益生菌食品因其改善肠道屏障功能、维持肠道免疫力和调节肠道微生物组的能力而作为治疗急性胰腺炎的一种潜在方法受到越来越多的关注。本综述总结了益生菌食品在治疗 AP 的动物研究和临床试验中的应用研究进展,包括益生菌食品中的菌株、剂量、持续时间和结论,并进一步讨论了益生菌食品治疗 AP 的潜在机制。尽管研究结果令人鼓舞,但仍存在一些局限性和悬而未决的问题,包括最佳益生菌菌株、干预时机和益生菌食品成分指南。未来需要进行大规模、多中心随机对照试验,以阐明益生菌食品对急性肠胃炎的疗效和机制,并解决目前的这些知识空白。
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引用次数: 0
Low resolution food fingerprinting: vibrational spectroscopic methods for nondestructive food authentication 低分辨率食品指纹识别:用于无损食品认证的振动光谱方法
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-12-01 Epub Date: 2024-10-09 DOI: 10.1016/j.cofs.2024.101229
Daniel Cozzolino
Methods and techniques used in food fingerprinting are required to be of low cost, rapid and easy to use to target issues associated with food authenticity (e.g. food fraud, provenance). The utilisation of sensing technologies based on vibrational spectroscopy, including mid-infrared, near-infrared and Raman spectroscopy, and, more recently, hyperspectral imaging are proposed and extensively used in food authenticity in a wide range of foods. The different studies and commercial applications reported concluded that the utilisation of vibrational spectroscopy allows for the development of efficient and robust systems to monitor food authenticity. These techniques have also shown their potential to be included in the implementation of management decision tools that would allow for the evaluation and monitoring of the authenticity of food supply and value chains.
用于食品指纹识别的方法和技术要求成本低、速度快且易于使用,以解决与食品真实性(如食品欺诈、来源)相关的问题。基于振动光谱的传感技术,包括中红外、近红外和拉曼光谱,以及最近提出并广泛应用于各种食品真伪鉴定的高光谱成像技术。所报告的不同研究和商业应用得出的结论是,利用振动光谱技术可以开发出高效、可靠的系统来监测食品真伪。这些技术还表明,它们有潜力被纳入管理决策工具的实施中,从而对食品供应和价值链的真实性进行评估和监测。
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引用次数: 0
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Current Opinion in Food Science
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