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Scientific Transparency: a New Horizon for Scientific Publication and the “New Cardiovascular Surgeon” 科学透明:科学出版的新视野与“新型心血管外科医生”
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2019-0608
D. Braile, P. Evora
there are several publications in national and international journals that show the field’s rich tradition in the development of surgical techniques and medicines, among other products. However, in recent years, information technology has significantly impacted medical practice, and with this, several challenges have emerged, such as the provision and dissemination of health care information. With the constant growth of health research, falsification, plagiarism, and data fabrication have been having a deleterious effect on the results presented. Unethical conduct in research drains the foundations of science which, by their very nature, are built on previous evidences, and if these are false, these foundations are logically weakened. In this context, it is up to the hard work of the editors of major scientific publications to ensure to the researchers and the society the dissemination of papers with reliable and transparent results. Research misconduct means fabrication, falsification, or plagiarism in proposing, performing, or reviewing research, or in reporting research results[1]. It is important to point out that misconduct does not include honest mistakes or differences of opinion. Scientific integrity consists in sticking to strategies that allow the promotion and development of ethical and honest scientific standards that guarantee objectivity, clarity, reproducibility, openness, and accessibility, the caring duty, fairness in providing references and giving credit, and responsibility to future scientists and researchers. This is one of the main concerns that scientific editors face daily, and this topic has been included in the Brazilian Journal of Cardiovascular Surgery’s (BJCVS) new instructions. Plagiarism consists in the appropriation of someone else’s ideas, processes, results, or words, without giving the appropriate credits. The authors are responsible for the content and the information in their manuscripts. BJCVS uses the Similarity Check software, which allows to detect similarities in the submitted EDITORIAL
在国家和国际期刊上有几篇出版物显示了该领域在外科技术和药物以及其他产品开发方面的丰富传统。然而,近年来,信息技术对医疗实践产生了重大影响,随之而来的是一些挑战,例如医疗保健信息的提供和传播。随着健康研究的不断发展,伪造、剽窃和数据捏造对所提供的结果产生了有害影响。研究中的不道德行为耗尽了科学的基础,而科学的基础从本质上讲是建立在以前的证据之上的,如果这些证据是错误的,那么这些基础在逻辑上就会被削弱。在这种情况下,主要科学出版物的编辑们要努力确保向研究人员和社会传播具有可靠和透明结果的论文。研究不端行为是指在提出、执行或审查研究或报告研究结果时捏造、篡改或抄袭[1]。需要指出的是,不当行为不包括诚实的错误或意见分歧。科学诚信包括坚持促进和发展道德和诚实的科学标准的战略,这些标准保证客观性、清晰性、可重复性、开放性和可访问性,关心他人的义务,提供参考和赞扬的公平性,以及对未来科学家和研究人员的责任。这是科学编辑每天面临的主要问题之一,这一主题已被纳入《巴西心血管外科杂志》(BJCVS)的新说明中。剽窃是指盗用他人的想法、过程、结果或文字,而没有给予适当的赞扬。作者对其手稿中的内容和信息负责。BJCVS使用相似性检查软件,该软件允许检测提交的EDITORIAL中的相似性
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引用次数: 1
Long-Term Assessment of Left Ventricular Ejection Fraction and Mitral Regurgitation Following Takeuchi Repair Takeuchi修复术后左心室射血分数和二尖瓣返流的长期评估
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2018-0376
Gökmen Akkaya, Ç. Bilen, O. Tuncer, M. Ayık, Y. Atay
Objective This study aimed to evaluate the early operative outcomes and to compare the left ventricle and mitral valve functions after initial Takeuchi repair in patients with anomalous left coronary arising from pulmonary artery (ALCAPA). Methods Fourteen patients (5 males, 9 females; mean age 4.3 years, ranging from 25 days to 34 years) who were operated for ALCAPA between 2007 and 2018 were included in this study. Data were evaluated retrospectively based on our medical records. Results Hospital mortality rate was 7.1% (n=1). Thirteen surviving patients were kept in follow-up mean 4.3±3.05 years. When compared to preoperative measurements, both left ventricular ejection fraction (LVEF), (P=0.007) and mitral regurgitation (MR) (P=0.001) significantly improved before discharge. Moreover, LVEF values were improved in the late follow-up, considering early postoperative outcomes, and this alteration was significant (P=0.014). Nevertheless, alteration in the degree of MR among patients did not differ in the long-term follow-up (P=0.180). There was no late-term mortality or need for reoperation among patients. Conclusion Although some centers prefer to direct implantation in ALCAPA, Takeuchi procedure can be accepted as a reliable method that provides satisfactory long-term results, considering that it aids to improve left ventricle ejection fraction and reduced mitral valve regurgitation.
目的评价肺动脉源性左冠状动脉异常(ALCAPA)患者初始Takeuchi修复术后的早期手术效果,并比较其左心室和二尖瓣功能。方法14例患者(男5例,女9例;本研究纳入2007年至2018年期间接受ALCAPA手术的患者,平均年龄4.3岁,年龄范围为25天至34岁。根据我们的医疗记录对数据进行回顾性评估。结果住院死亡率为7.1% (n=1)。13例存活患者平均随访4.3±3.05年。与术前测量结果相比,出院前左心室射血分数(LVEF) (P=0.007)和二尖瓣返流(MR) (P=0.001)均显著改善。此外,考虑到术后早期结局,LVEF值在随访后期有所改善,且差异有统计学意义(P=0.014)。然而,在长期随访中,患者MR程度的改变没有差异(P=0.180)。所有患者均无晚期死亡或需要再手术。结论虽然一些中心倾向于直接植入ALCAPA,但Takeuchi手术可以提高左心室射血分数,减少二尖瓣反流,是一种可靠的方法,可以提供满意的长期效果。
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引用次数: 1
Quadricuspid Aortic Valve: Three Cases Report and Literature Review 四尖瓣主动脉瓣:3例报告并文献复习
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2018-0125
Elinthon T Veronese, C. Brandão, S. Steffen, P. Pomerantzeff, F. Jatene
Quadricuspid aortic valve (QAV) is a rare cardiac malformation. Many cases are incidentally diagnosed in aortic surgeries or autopsies and it usually appears as an isolated anomaly. The most widely classification used is the one by Hurwitz and Roberts[1], which divides 7 alphabetical subtypes based on the cusps size. The aim of this report is to describe three different anatomic presentations of this rare aortic valve anomaly.
四叶主动脉瓣(QAV)是一种罕见的心脏畸形。许多病例是在主动脉手术或尸检中偶然诊断出来的,通常表现为孤立的异常。使用最广泛的分类是Hurwitz和Roberts[1]的分类,该分类根据尖端的大小划分了7个字母亚型。本报告的目的是描述这种罕见主动脉瓣异常的三种不同解剖表现。
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引用次数: 6
"Overtime Hours Effect" on Emergency Surgery of Acute Type A Aortic Dissection 急性A型主动脉夹层急诊手术的“加班效应
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2018-0350
O. Gokalp, L. Yılık, Y. Beşir, H. Iner, Nihan KarakasYesilkaya, Erturk Karaagac, Yasar Gokkurt, S. Iscan, A. Gurbuz
Objective Treatment of acute diseases of the aorta is still associated with high mortality and morbidity. It is believed that interventions for these diseases on overtime hours (night shifts or weekend shifts) may increase mortality. In this study, we investigated the effect of performing acute type A aortic dissection surgery on overtime hours in terms of postoperative outcomes. Methods 206 patients who underwent emergency surgery for acute type A aortic dissection were retrospectively evaluated. Two groups were constituted: patients operated on daytime working hours (n=61), and patients operated on overtime hours (n=145), respectively. Results Chronic obstructive pulmonary disease and repeat surgery were higher in group 1. There was no statistically significant difference between the two groups in terms of operative and postoperative results. Mortality rates and postoperative neurological complications in group 1 were 9.8% and 13.1%, respectively. In group 2, these rates were 13.8% and 12.4%, respectively (P=0.485 - P=0.890). Multivariate analysis identified that cross-clamp time, amount of postoperative drainage, preoperative loss of consciousness and postoperative neurological complications are the independent predictors of mortality. Conclusions As the surgical experience of the clinics improves, treatment of acute type A aortic dissections can be successfully performed both overtime and daytime working hours.
目的主动脉急性疾病的治疗仍然具有较高的死亡率和发病率。据信,在加班时间(夜班或周末轮班)对这些疾病进行干预可能会增加死亡率。在这项研究中,我们调查了进行急性A型主动脉夹层手术对加班时间的影响。方法对206例急性A型主动脉夹层急诊手术患者进行回顾性分析。两组患者分别在白天工作时间(n=61)和加班时间(n=145)进行手术。结果1组慢性阻塞性肺疾病和重复手术发生率较高。在手术和术后结果方面,两组之间没有统计学上的显著差异。第1组的死亡率和术后神经系统并发症分别为9.8%和13.1%。第2组的死亡率分别为13.8%和12.4%(P=0.485-P=0.890)。多因素分析表明,交叉钳时间、术后引流量、术前意识丧失和术后神经并发症是死亡率的独立预测因素。结论随着临床手术经验的提高,急性A型主动脉夹层的治疗可以在加班和白天工作的同时成功进行。
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引用次数: 5
Anesthesia Management for a Patient Undergoing Pulmonary Endarterctomy without Cardiopulmonary Bypass 非体外循环肺动脉内膜切除术患者的麻醉管理
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2018-0245
A. Saraçoğlu, Onur Ermerak, Esra Yaman Savci Sirzai, M. Yuksel, Z. Aykaç, B. Yıldızeli
Pulmonary endarterectomy is a curative procedure for chronic thromboembolic Pulmonary Hypertension. As usual, cardiopulmonary bypass circuit is required. However, there are several complications attributed to extracorporeal circulation. Hemodilution, systemic inflammatory response syndrome and leukocyte sequestration are circulation related complications. The severe forms include Acute Respiratory Distress Syndrome, Acute Lung Injury, myocardial stunning, dysfunction of the right ventricle, coagulopathy, postoperative stroke or renal dysfunction. In this case report, we aimed to give information about perioperative anesthesia and surgical management of pulmonary endarterectomy which was successfully managed without Cardiopulmonary Bypass.
肺动脉内膜切除术是一种治疗慢性血栓栓塞性肺动脉高压的方法。像往常一样,需要进行体外循环。然而,有一些并发症归因于体外循环。血液稀释、全身炎症反应综合征和白细胞隔离是循环相关的并发症。严重的形式包括急性呼吸窘迫综合征、急性肺损伤、心肌昏迷、右心室功能障碍、凝血功能障碍、术后中风或肾功能障碍。在这个病例报告中,我们的目的是提供关于肺动脉内膜切除术的围手术期麻醉和手术管理的信息,该手术成功地在没有体外循环的情况下进行。
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引用次数: 0
Botulinum Toxin Injection into Epicardial Fat Pads: A Promising Potential Modality for Prevention of Postoperative Atrial Fibrillation After Cardiac Surgery 肉毒毒素注射心外膜脂肪垫:预防心脏手术后房颤的一种有前景的潜在方式
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2019-0309
A. Fatahian
Despite developing new standards and advances in anesthetic and surgical techniques, postoperative atrial fibrillation (POAF) is one of the most frequent complications and a significant unsolved clinical problem after cardiac surgery[1]. Occurrence of POAF is associated with significant increased risk of long-term mortality, morbidity, and long intensive care unit (ICU) and hospital stays, which consequently impose additional cost on both health system and patient[2]. Considering the potential significant adverse effects of POAF in patients undergoing cardiac surgery and the limited efficacy of current preventive strategies, concerted efforts to identify and implement new preventive strategies are necessary[1,2]. Recently, injection of botulinum toxin into epicardial fat pads in patients undergoing cardiac surgery has been suggested as a promising modality for prevention of POAF. In a study by Pokushalov et al.[3], it has been shown that 50 U botulinum toxin injection, at four major epicardial fat pads, during surgery in patients undergoing coronary artery bypass grafting (CABG) provided considerable atrial tachyarrhythmia suppression, in both early and one-year followups[3]. Also, a three-year follow-up of this study indicates a sustained and significant reduction in atrial fibrillation (AF) incidence and burden, along with reduction in patients' hospitalizations. Besides, no serious adverse events related to injection of botulinum toxin for prevention of POAF after CABG have been reported[4]. Suppression of atrial autonomic remodeling has been suggested as a potential mechanism of botulinum toxin injection for prevention of POAF[34]. Another study by Waldron et al.[5] showed that injection of 50 U of botulinum toxin into each five epicardial fat pads (immediately after beginning of cardiopulmonary bypass) in patients undergoing cardiac surgery reduced the incidence of POAF compared to placebo (36.5% and 47.8%, respectively), however this difference was not statistically significant. Also, no significant differences were seen between length of hospital stay and occurrence of adverse effects in patients who received botulinum toxin injection or placebo[5]. In this study, patients who underwent CABG or valve surgery or combined CABG and valve surgery were included; whereas in Pokushalov et al.[3] one-year and three-year follow-up studies[4], only CABG patients were included and evaluated. Additionally, the left atrial sizes, as a marker of atrial structural remodeling, which commonly is associated with increased risk for AF, were considerably different between these studies (3.9±0.6 and 3.9±0.7 cm vs. 4.7±0.8 and 4.8±0.6, respectively). These issues may be possible explanations for the inconsistent results between studies. In sum, it seems that botulinum toxin injection into epicardial fat pads may be considered as a potentially promising and safe modality for prevention of POAF after cardiac surgery. However, further well-designed studies will be
尽管在麻醉和外科技术方面有了新的标准和进步,但术后心房颤动(POAF)是心脏手术后最常见的并发症之一,也是一个尚未解决的重要临床问题[1]。POAF的发生与长期死亡率、发病率、长期重症监护室(ICU)和住院的风险显著增加有关,从而给卫生系统和患者带来额外成本[2]。考虑到POAF对接受心脏手术的患者可能产生的重大不良影响,以及当前预防策略的有限疗效,有必要共同努力确定和实施新的预防策略[1,2]。最近,在接受心脏手术的患者的心外膜脂肪垫中注射肉毒杆菌毒素被认为是预防POAF的一种很有前途的方式。Pokusalov等人[3]的一项研究表明,在接受冠状动脉搭桥术(CABG)的患者手术期间,在四个主要心外膜脂肪垫处注射50U肉毒杆菌毒素,在早期和一年的随访中都能显著抑制心房快速性心律失常[3]。此外,这项研究的三年随访表明,心房颤动(AF)的发病率和负担持续显著降低,患者住院人数也有所减少。此外,目前尚无与CABG后注射肉毒杆菌毒素预防POAF相关的严重不良事件的报道[4]。抑制心房自主神经重塑已被认为是肉毒杆菌毒素注射预防POAF的潜在机制[34]。Waldron等人[5]的另一项研究表明,与安慰剂(分别为36.5%和47.8%)相比,在接受心脏手术的患者中,每五个心外膜脂肪垫中注射50 U肉毒杆菌毒素(心肺转流开始后立即注射)可降低POAF的发生率,但这一差异在统计学上并不显著。此外,在接受肉毒杆菌毒素注射或安慰剂治疗的患者中,住院时间和不良反应发生率之间没有显著差异[5]。在这项研究中,接受CABG或瓣膜手术或CABG和瓣膜联合手术的患者包括在内;而在Pokusalov等人[3]的一年和三年随访研究[4]中,仅纳入并评估了CABG患者。此外,作为心房结构重塑的标志物,左心房大小通常与房颤风险增加有关,在这些研究之间差异很大(分别为3.9±0.6和3.9±0.7 cm,而4.7±0.8和4.8±0.6)。这些问题可能是研究结果不一致的原因。总之,将肉毒杆菌毒素注射到心外膜脂肪垫中似乎可以被认为是一种潜在的、有前途的、安全的预防心脏手术后POAF的方法。然而,在控制了潜在的混杂因素(如手术类型、左心房大小、肉毒杆菌毒素的剂量和注射部位等)后,还需要进一步精心设计的研究来研究这种预防方式对心脏手术患者POAF的疗效。
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引用次数: 3
Appropriate Surgical Repair of Ventricular Free Wall Rupture after Infarction: a Case Report 心肌梗死后心室游离壁破裂的手术治疗1例
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2018-0205
U. S. Sanrı, K. K. Özsin, F. Toktaş, Ş. Yavuz
Ventricular free wall rupture is a fatal mechanical complication of acute myocardial infarction. In some cases it can be represented as subacute clinic and may not cause death in a few minutes. Acute pseudo-aneurysms are extremely unstable and bound to fatal rupture. Herein we report a male patient who suffered dyspnea and mild chest pain, 4 weeks after acute ST-segment elevation myocardial infarction.
心室游离壁破裂是急性心肌梗死的一种致命的机械并发症。在某些情况下,它可以表现为亚急性临床,可能不会在几分钟内导致死亡。急性假性动脉瘤是极不稳定的,注定会致命破裂。在此,我们报告了一名男性患者,在急性ST段抬高型心肌梗死4周后出现呼吸困难和轻度胸痛。
{"title":"Appropriate Surgical Repair of Ventricular Free Wall Rupture after Infarction: a Case Report","authors":"U. S. Sanrı, K. K. Özsin, F. Toktaş, Ş. Yavuz","doi":"10.21470/1678-9741-2018-0205","DOIUrl":"https://doi.org/10.21470/1678-9741-2018-0205","url":null,"abstract":"Ventricular free wall rupture is a fatal mechanical complication of acute myocardial infarction. In some cases it can be represented as subacute clinic and may not cause death in a few minutes. Acute pseudo-aneurysms are extremely unstable and bound to fatal rupture. Herein we report a male patient who suffered dyspnea and mild chest pain, 4 weeks after acute ST-segment elevation myocardial infarction.","PeriodicalId":54481,"journal":{"name":"Revista Brasileira De Cirurgia Cardiovascular","volume":"34 1","pages":"775 - 778"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43450193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Mass Causing Right Ventricular Outflow Obstruction - A Dreadful Complication 一个肿块引起右心室流出梗阻——一个可怕的并发症
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2018-0314
Rupesh Kumar, Javid Raja
The most common cardiac tumour in the pediatric age group is rhabdomyoma. These are usually located in the ventricles, either in the ventricular septum or free wall. Cardiac tumours in early infancy may lead to severely compromised blood flow due to inflow or outflow tract obstruction. The diagnosis of cardiac rhabdomyoma can be established by transthoracic echocardiography (TTE). Rhabdomyomas have a natural history of spontaneous regression; surgical intervention is reserved for patients with symptoms of severe obstruction or hemodynamic instability. In this study, a case of two-year old child who presented with failure to thrive and underwent excision of pedunculated mass from the right ventricular outflow tract was reported.
在儿童年龄组最常见的心脏肿瘤是横纹肌瘤。它们通常位于心室,在室间隔或游离壁。婴儿早期的心脏肿瘤可能导致严重的血流受损,由于流入或流出道阻塞。心脏横纹肌瘤的诊断可以通过经胸超声心动图(TTE)来确定。横纹肌瘤有自然消退的历史;手术干预保留给有严重阻塞症状或血流动力学不稳定的患者。在本研究中,我们报告了一名两岁的儿童,他表现出发育不佳,并接受了右心室流出道带蒂肿块切除术。
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引用次数: 0
Challenges in Diagnosis and Management of Spontaneous Coronary Artery Dissection in a Young Patient 一例年轻自发性冠状动脉夹层的诊断和治疗挑战
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2018-0198
Beatriz J. S. Branco, Cesar Sanchez, C. Mendoza, M. Magarakis, Alejandro E. Macias, T. Salerno
Spontaneous coronary artery dissection (SCAD) is characterized by tear of the inner layer in the coronary artery, creating a false lumen between the inner and central layer. Its infrequent incidence often leads to delay in diagnosis posing challenges in management. There are currently no guidelines for the treatment of this condition. We describe an adult patient who presented with multiple episodes of ventricular fibrillation, in whom cardiac catheterization showed SCAD, treated by off-pump coronary artery bypass.
自发性冠状动脉夹层(SCAD)的特征是冠状动脉内层撕裂,在内层和中心层之间形成假管腔。其罕见的发病率往往导致诊断延迟,给管理带来挑战。目前还没有治疗这种疾病的指南。我们描述了一名成年患者,他表现出多发性心室颤动,心导管插入术显示SCAD,接受非体外循环冠状动脉搭桥术治疗。
{"title":"Challenges in Diagnosis and Management of Spontaneous Coronary Artery Dissection in a Young Patient","authors":"Beatriz J. S. Branco, Cesar Sanchez, C. Mendoza, M. Magarakis, Alejandro E. Macias, T. Salerno","doi":"10.21470/1678-9741-2018-0198","DOIUrl":"https://doi.org/10.21470/1678-9741-2018-0198","url":null,"abstract":"Spontaneous coronary artery dissection (SCAD) is characterized by tear of the inner layer in the coronary artery, creating a false lumen between the inner and central layer. Its infrequent incidence often leads to delay in diagnosis posing challenges in management. There are currently no guidelines for the treatment of this condition. We describe an adult patient who presented with multiple episodes of ventricular fibrillation, in whom cardiac catheterization showed SCAD, treated by off-pump coronary artery bypass.","PeriodicalId":54481,"journal":{"name":"Revista Brasileira De Cirurgia Cardiovascular","volume":"34 1","pages":"779 - 782"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44974274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis 预测多支冠状动脉疾病患者颈动脉狭窄的语法评分I和II:倾向评分匹配分析
4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2019-12-01 DOI: 10.21470/1678-9741-2019-0067
S. Ozturk, M. Şahin
Objective To evaluate the predictive accuracy of SYNTAX score (SS) I and II for detecting significant carotid artery stenosis (CAS) in patients with multivessel coronary artery disease undergoing coronary artery bypass grafting (CABG) surgery. Methods The study population consisted of 416 patients. Clinical, demographic, and radiological records were retrospectively reviewed. Characteristics of patients with CAS (n=66) and patients without CAS (n=350) were compared before and after propensity score matching analysis. Results Patients with significant CAS were older compared to those without significant CAS [(60 (53-65) vs. 63 (59-67); P=0.01]. However, atherosclerotic risk factors and SS I were similar between groups. SS II CABG and percutaneous coronary intervention (PCI) were significantly higher in patients with CAS [37.4 (30.9-43.5) vs. 33.8 (29.9-38.9); P=0.02]. After propensity score matching analysis (66 vs. 66), age, SS II PCI and CABG were significantly higher in patients with CAS than those without CAS [37.4 (30.9-43.5) vs. 33 (29.3-36.9); P=0.03]. Age, SS II PCI and CABG were associated with CAS in logistic regression analysis [OR=1.086, 95% CI (1.032-1.143), P<0.001; OR=1.054, 95% CI (1.010-1.101), P=0.02; OR=1.078, 95% CI (1.029-1.129), P<0.01]. In ROC curve analysis, SS II PCI >33.1 had 68.2% sensitivity and 54.6% specificity [AUC=0.624, P=0.01, 95% CI (0.536-0.707)] whereas SS II CABG >26.1 had 81.8% sensitivity and 54.6% specificity [AUC=0.670, P<0.01, 95% CI (0.583-0.749)] to predict CAS. Pairwise comparison of ROC curves revealed similar statistical accuracy for prediction of CAS (z statistic: 0.683, P=0.49) Conclusion SS II is useful to predict asymptomatic CAS in patients with multivessel coronary artery disease.
目的评价SYNTAX评分(SS) I和II对多支冠状动脉病变行冠状动脉搭桥术(CABG)患者颈动脉明显狭窄(CAS)的预测准确性。方法研究人群为416例。回顾性回顾临床、人口统计学和放射学记录。比较倾向评分匹配分析前后CAS患者(n=66)和非CAS患者(n=350)的特征。结果与无显著CAS的患者相比,显著CAS患者年龄较大[60(53-65)比63 (59-67);P = 0.01)。然而,两组之间的动脉粥样硬化危险因素和SS I相似。在CAS患者中,SS II CABG和经皮冠状动脉介入治疗(PCI)的评分明显更高[37.4(30.9-43.5)比33.8 (29.9-38.9);P = 0.02)。经倾向评分匹配分析(66比66),有CAS患者的年龄、SS II PCI和CABG明显高于无CAS患者[37.4(30.9-43.5)比33 (29.3-36.9);P = 0.03)。logistic回归分析显示,年龄、SS II PCI和CABG与CAS相关[OR=1.086, 95% CI (1.032-1.143), P33.1预测CAS的敏感性为68.2%,特异性为54.6% [AUC=0.624, P=0.01, 95% CI(0.536-0.707)],而SS II CABG bbb26.1预测CAS的敏感性为81.8%,特异性为54.6% [AUC=0.670, P<0.01, 95% CI(0.583-0.749)]。ROC曲线两两比较显示,预测无症状冠状动脉综合征(CAS)的统计准确率相近(z统计量:0.683,P=0.49)。结论SSⅱ可用于预测多支冠状动脉病患者无症状CAS。
{"title":"Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis","authors":"S. Ozturk, M. Şahin","doi":"10.21470/1678-9741-2019-0067","DOIUrl":"https://doi.org/10.21470/1678-9741-2019-0067","url":null,"abstract":"Objective To evaluate the predictive accuracy of SYNTAX score (SS) I and II for detecting significant carotid artery stenosis (CAS) in patients with multivessel coronary artery disease undergoing coronary artery bypass grafting (CABG) surgery. Methods The study population consisted of 416 patients. Clinical, demographic, and radiological records were retrospectively reviewed. Characteristics of patients with CAS (n=66) and patients without CAS (n=350) were compared before and after propensity score matching analysis. Results Patients with significant CAS were older compared to those without significant CAS [(60 (53-65) vs. 63 (59-67); P=0.01]. However, atherosclerotic risk factors and SS I were similar between groups. SS II CABG and percutaneous coronary intervention (PCI) were significantly higher in patients with CAS [37.4 (30.9-43.5) vs. 33.8 (29.9-38.9); P=0.02]. After propensity score matching analysis (66 vs. 66), age, SS II PCI and CABG were significantly higher in patients with CAS than those without CAS [37.4 (30.9-43.5) vs. 33 (29.3-36.9); P=0.03]. Age, SS II PCI and CABG were associated with CAS in logistic regression analysis [OR=1.086, 95% CI (1.032-1.143), P<0.001; OR=1.054, 95% CI (1.010-1.101), P=0.02; OR=1.078, 95% CI (1.029-1.129), P<0.01]. In ROC curve analysis, SS II PCI >33.1 had 68.2% sensitivity and 54.6% specificity [AUC=0.624, P=0.01, 95% CI (0.536-0.707)] whereas SS II CABG >26.1 had 81.8% sensitivity and 54.6% specificity [AUC=0.670, P<0.01, 95% CI (0.583-0.749)] to predict CAS. Pairwise comparison of ROC curves revealed similar statistical accuracy for prediction of CAS (z statistic: 0.683, P=0.49) Conclusion SS II is useful to predict asymptomatic CAS in patients with multivessel coronary artery disease.","PeriodicalId":54481,"journal":{"name":"Revista Brasileira De Cirurgia Cardiovascular","volume":"34 1","pages":"653 - 658"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47827655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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Revista Brasileira De Cirurgia Cardiovascular
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