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Left Ventricular Assist Device Thrombosis: Combined Approach by Echocardiography and Logfiles Review for Diagnosis and Management 左心室辅助装置血栓形成:超声心动图和日志文件的联合诊断和治疗
4区 医学 Q3 Medicine Pub Date : 2022-05-02 DOI: 10.21470/1678-9741-2021-0139
N. Vitale, T. Acquaviva, Teresa A P Quagliara, N. Bari, G. Capone, N. Marraudino, A. Milano
Introduction Left ventricular assist devices are an established therapy for end-stage heart failure. Follow-up of these patients showed complications, such as thrombosis. Our objective was to evaluate the contribution of echocardiography — in association with HeartWare HVAD online logfiles reviews and lactate dehydrogenase titration — for diagnosis and treatment of thrombosis. Methods Seventeen episodes of thrombosis were diagnosed in 8/20 patients with HVAD. Diagnosis was made by trans-thoracic echocardiographic blood flow velocities, logfiles review of power consumption and pump flows, and titration of lactate dehydrogenase. Data were collected at baseline routine control (Group A), during thrombosis (Group B), after thrombolysis (Group C). Results Thrombolysis was successful in all cases; one patient died of cerebral haemorrhage. Echocardiographic maximal blood flow velocity near the inflow cannula was 598±42 cm/sec (Group B), 379.41±21 cm/sec (Group C), and 378.24±28 cm/sec (Group A) (P<0.00001). In eight (47%) cases, thrombi were visualized in the left ventricle by three-dimensional modality. Logfiles recordings of blood flows were 9.52±0.9 L/min (Group B), 4.02±0.4 L/min (Group C), and 4.04±0.4 L/min (Group A) (P<00001). Power consumption was 5.01±0.7 W (Group B), 3.45±0.2 W (Group C), and 3.46±0.2 W (Group A) (P<0.00001). Lactate dehydrogenase was 756±54 IU (Group B), 234±22 IU (Group A), and 257±36 IU (Group C) (P<0.00001). Conclusions Echocardiography of increased maximal velocity near the inflow cannula is a sign of HVAD obstruction. Logfile reviews provide a clear picture of HVAD obstruction. Combination of echocardiographic data and review of logfiles detects signs of left ventricular assist devices thrombosis leading to a successful treatment.
左心室辅助装置是终末期心力衰竭的常用治疗方法。随访发现患者出现血栓形成等并发症。我们的目的是评估超声心动图的贡献-与HeartWare HVAD在线日志文件回顾和乳酸脱氢酶滴定-诊断和治疗血栓形成。方法20例HVAD患者中有8例有血栓形成。通过经胸超声心动图血流速度、功率消耗和泵流量日志回顾、乳酸脱氢酶滴定进行诊断。收集基线常规对照(A组)、血栓形成时(B组)、溶栓后(C组)的数据。结果所有病例溶栓均成功;1例患者死于脑溢血。B组、C组和A组的超声心动图最大血流速度分别为598±42 cm/sec、379.41±21 cm/sec和378.24±28 cm/sec (P<0.00001)。在8例(47%)病例中,血栓在左心室通过三维模式可见。血流量日志记录分别为9.52±0.9 L/min (B组)、4.02±0.4 L/min (C组)、4.04±0.4 L/min (A组)(P<00001)。功耗分别为5.01±0.7 W (B组)、3.45±0.2 W (C组)和3.46±0.2 W (A组)(P<0.00001)。乳酸脱氢酶分别为756±54 IU (B组)、234±22 IU (A组)和257±36 IU (C组)(P<0.00001)。结论超声心动图显示流入管附近最大流速增高是HVAD梗阻的标志。日志文件检查提供了HVAD阻塞的清晰图像。结合超声心动图数据和回顾日志文件检测左心室辅助装置血栓形成的迹象,导致成功的治疗。
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引用次数: 1
Combined Heart and Kidney Transplantation: Initial Clinical Experience 心肾联合移植:初步临床经验
4区 医学 Q3 Medicine Pub Date : 2022-05-02 DOI: 10.21470/1678-9741-2020-0720
F. Atik, Carolina de Castro Borges, M. Ulhoa, R. Chaves, Vitor Barzilai, R. Biondi, Tiago Martins de Almeida, Isabela Medeiros, H. Cardoso
Introduction Combined solid organ transplantation is infrequently performed in Brazil. The objective of this article is to present our initial experience with combined heart and kidney transplantation. Methods From January 2007 to December 2019, four patients were submitted to combined heart and kidney transplantation. Their mean age was 55.7±4.4 years, and three (75%) patients were males. All patients had Chagas cardiomyopathy, two were hospitalized and inotrope dependent, and all patients were on preoperative dialysis (median of 12 months prior to transplant). Results All patients survived and were in New York Heart Association functional class I at the latest follow-up (mean 34.7±17.5 months). Mean retarded kidney graft function was 22.9±9.7 days. One patient lost the kidney graft two years after the transplant due to Polyomavirus infection. Conclusion Our initial experience of combined heart and kidney transplantation was favorable in selected patients with advanced heart failure and end-stage kidney disease. It requires involvement of a dedicated multispecialty team throughout all the diagnostics and treatment steps.
联合实体器官移植在巴西并不常见。本文的目的是介绍我们在心脏和肾脏联合移植方面的初步经验。方法2007年1月至2019年12月,4例患者行心肾联合移植。平均年龄55.7±4.4岁,男性3例(75%)。所有患者均患有恰加斯心肌病,其中2例住院并依赖于肌力,所有患者术前透析(移植前12个月中位数)。结果所有患者均存活,最新随访时纽约心脏协会功能分级为I级(平均34.7±17.5个月)。移植肾功能迟滞平均为22.9±9.7天。一名患者因多瘤病毒感染在移植两年后失去了肾移植。结论我们对晚期心力衰竭和终末期肾病患者进行心脏和肾脏联合移植的初步经验是有利的。它需要一个专门的多专业团队参与所有的诊断和治疗步骤。
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引用次数: 0
Transcatheter Edge-to-Edge Mitral Valve Repair in Functional Mitral Regurgitation. Does it Pass Muster? Still Leaving Plenty to Be Desired 功能性二尖瓣反流中经导管边缘对边缘二尖瓣修复术。它通过Muster吗?仍留下许多值得渴望的东西
4区 医学 Q3 Medicine Pub Date : 2022-05-02 DOI: 10.21470/1678-9741-2022-0129
O. García-Villarreal
The usefulness of percutaneous approaches in structural heart disease could be limited if they have been defined in terms of often unrealistic scenarios. Thus, the long-term outcomes and consequences need to be painstakingly analyzed. Much attention needs to be paid to the global magnitude of this issue. One such example, is the transcatheter edge-to-edge mitral valve repair (TEER) and considerations of pivotal importance that arise from using this therapy to treat functional mitral regurgitation (FMR). Traditionally, surgical treatment has been the best option for mitral valve (MV) repair. When comparing TEER to surgical MV repair, details to be considered. One of the drawbacks of the that
经皮入路在结构性心脏病中的作用可能会受到限制,如果它们被定义为通常不现实的情况。因此,需要仔细分析长期结果和后果。需要对这一问题的全球规模给予高度注意。其中一个例子是经导管边缘到边缘二尖瓣修复(TEER),并考虑到使用这种疗法治疗功能性二尖瓣反流(FMR)的关键重要性。传统上,手术治疗是二尖瓣修复的最佳选择。当比较TEER和手术修复时,需要考虑细节。它的一个缺点是
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引用次数: 0
Proadrenomedullin in Patients with Preserved Left Ventricular Systolic Function Undergoing Coronary Artery Bypass Grafting 肾上腺髓质素原在冠状动脉搭桥术后左心室收缩功能保持的患者中的作用
4区 医学 Q3 Medicine Pub Date : 2022-05-02 DOI: 10.21470/1678-9741-2020-0616
Joanna Stanisz-Kempa, Z. Gąsior, A. Kułach
Introduction A potentially new marker of cardiovascular diseases — proadrenomedullin is the precursor of adrenomedullin, which is a multifunctional peptide hormone, produced in most of the tissues in response to cellular stress, ischemia, and hypoxia. Methods Ninety-three people, aged 51-79 years, were included in the study. Exclusion criteria were severe or corrected valvular disease, acute coronary syndrome, age ≥ 80 years, glomerular filtration rate < 45 ml/min, active infectious diseases, and cancer. The subjects were observed for adverse events, including reduced left ventricular ejection fraction (LVEF) by ≥ 10%, first incidence of atrial fibrillation (AF), and the necessity of using dopamine during hospitalization. Results Use of pressure amines, occurrence of the first AF episode, and left ventricular dysfunction defined by a decrease in LVEF by at least 10% compared to the value before surgery were reported in the perioperative period. No death, sudden cardiac arrest with effective resuscitation, non-ST-elevation myocardial infarction, ST-elevation myocardial infarction, or heart failure were observed. Significantly higher proadrenomedullin concentration was observed in the group with reduced postoperative LVEF (1.68 vs. 0.77 nmol/l, P=0.005). The relative risk of a decrease in ejection fraction in the group of patients with proadrenomedullin concentration ≥ 0.77 nmol/l was more than twelve-fold higher (95% confidence interval 1.69-888.33; P=0.013) than in the group of patients with a concentration of proadrenomedullin < 0.77 nmol/l. Conclusion The higher baseline concentration of proadrenomedullin has a predominantly predictive value of postoperative left ventricular systolic dysfunction.
引言一种潜在的心血管疾病新标志物——肾上腺髓质素原是肾上腺髓质素的前体,肾上腺髓质素是一种多功能肽类激素,在大多数组织中产生,以应对细胞应激、缺血和缺氧。方法93例患者,年龄51~79岁。排除标准为严重或已纠正的瓣膜病、急性冠状动脉综合征、年龄≥80岁、肾小球滤过率<45 ml/min、活动性传染病和癌症。观察受试者的不良事件,包括左心室射血分数(LVEF)降低≥10%、首次发生心房颤动(AF)以及住院期间使用多巴胺的必要性。结果围手术期报告了压力胺的使用、第一次房颤发作的发生以及左心室功能障碍,即LVEF比手术前下降至少10%。未观察到死亡、经有效复苏的心脏骤停、非ST段抬高型心肌梗死、ST段抬高心肌梗死或心力衰竭。术后LVEF降低组的前肾上腺髓质素浓度显著升高(1.68 vs.0.77 nmol/l,P=0.005)。前肾上腺髓素浓度≥0.77 nmol的患者射血分数降低的相对风险是LVEF降低患者的12倍以上(95%置信区间1.69-888.33;P=0.013)肾上腺髓质素原浓度<0.77nmol/l。结论较高的前肾上腺髓质素基线浓度对术后左心室收缩功能障碍具有重要的预测价值。
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引用次数: 0
Lutembacher Syndrome with Sinus Venosus-Type Interatrial Communication: An Educational Presentation Lutembacher综合征伴静脉窦型房间通讯:教育报告
4区 医学 Q3 Medicine Pub Date : 2022-04-18 DOI: 10.21470/1678-9741-2021-0323
A. Lordsleem, S. G. de Lima, L. S. Bezerra, E. B. Calado, Fábio Antônio A. Granja, B. Markman-Filho
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引用次数: 1
Follow-up Results of Endovascular Aneurysm Repair Following Abdominal Visceral Debranching 腹腔内脏去分支术后血管内动脉瘤修复的随访结果
4区 医学 Q3 Medicine Pub Date : 2022-04-18 DOI: 10.21470/1678-9741-2020-0705
D. Oztas, M. Uğurlucan, O. Sayin, F. Ekiz, Yilmaz Onal, M. O. Beyaz, M. Umutlu, Mert Meriç, B. Acunaş, U. Alpagut
Introduction The aim of this study is to present a series of six cases with thoracoabdominal aneurysm treated with hybrid technique in our center. Methods Between May 2015 and December 2018, the data of six patients with thoracoabdominal aneurysms and various comorbidities who underwent visceral debranching followed by endovascular aortic aneurysm repair were reviewed retrospectively. Results Patients’ mean age was 65.3±19.6 years. All of them were male. Comorbidities were old age, congestive heart failure, coronary artery disease, chronic obstructive pulmonary disease, previous surgical interventions, and/or esophageal hemangioma. Except for one patient who underwent coronary artery bypass grafting (inflow was taken from ascending aorta), debranching was performed from the right iliac artery. Debranching of four visceral arteries (superior mesenteric artery, celiac trunk, and bilateral renal right arteries) was performed in three patients, of three visceral arteries (superior mesenteric artery, celiac trunk, right renal artery) was performed in one, and of two visceral arteries (superior mesenteric artery, celiac trunk) was performed in two patients. Great saphenous vein and 6-mm polytetrafluoroethylene grafts were used in one and five patients, respectively, for debranching. Endovascular aneurysm repair was performed following debranching procedures as soon as the patients were stabilized. In total, three patients died at the early, mid, and long-term follow-up due to multiorgan failure, pneumonia, and unknown reasons. Conclusion Hybrid repair of thoracoabdominal aneurysms may be an alternative to fenestrated or branched endovascular stent grafts in patients with increased risk factors for open surgical thoracoabdominal aneurysm repair; however, the procedure requires experience and care.
本研究的目的是报告在我中心采用混合技术治疗胸腹动脉瘤的6例病例。方法回顾性分析2015年5月至2018年12月6例胸腹动脉瘤合并各种合并症患者行内脏去分支后血管内动脉瘤修复术的资料。结果患者平均年龄65.3±19.6岁。他们都是男性。合并症为老年、充血性心力衰竭、冠状动脉疾病、慢性阻塞性肺疾病、既往手术干预和/或食管血管瘤。除1例患者行冠状动脉旁路移植术(流入源自升主动脉)外,均行右髂动脉脱支术。4条内脏动脉(肠系膜上动脉、腹腔干、双侧肾右动脉)脱支3例,3条内脏动脉(肠系膜上动脉、腹腔干、右肾动脉)脱支1例,2条内脏动脉(肠系膜上动脉、腹腔干)脱支2例。大隐静脉和6毫米聚四氟乙烯移植物分别用于1例和5例去分支。当患者病情稳定后,立即进行血管内动脉瘤修复。共有3例患者在早、中、长期随访中因多器官功能衰竭、肺炎及不明原因死亡。结论在危险因素增高的胸腹动脉瘤开放性手术中,混合型胸腹动脉瘤修复术可替代开窗或支状血管内支架;然而,这个过程需要经验和小心。
{"title":"Follow-up Results of Endovascular Aneurysm Repair Following Abdominal Visceral Debranching","authors":"D. Oztas, M. Uğurlucan, O. Sayin, F. Ekiz, Yilmaz Onal, M. O. Beyaz, M. Umutlu, Mert Meriç, B. Acunaş, U. Alpagut","doi":"10.21470/1678-9741-2020-0705","DOIUrl":"https://doi.org/10.21470/1678-9741-2020-0705","url":null,"abstract":"Introduction The aim of this study is to present a series of six cases with thoracoabdominal aneurysm treated with hybrid technique in our center. Methods Between May 2015 and December 2018, the data of six patients with thoracoabdominal aneurysms and various comorbidities who underwent visceral debranching followed by endovascular aortic aneurysm repair were reviewed retrospectively. Results Patients’ mean age was 65.3±19.6 years. All of them were male. Comorbidities were old age, congestive heart failure, coronary artery disease, chronic obstructive pulmonary disease, previous surgical interventions, and/or esophageal hemangioma. Except for one patient who underwent coronary artery bypass grafting (inflow was taken from ascending aorta), debranching was performed from the right iliac artery. Debranching of four visceral arteries (superior mesenteric artery, celiac trunk, and bilateral renal right arteries) was performed in three patients, of three visceral arteries (superior mesenteric artery, celiac trunk, right renal artery) was performed in one, and of two visceral arteries (superior mesenteric artery, celiac trunk) was performed in two patients. Great saphenous vein and 6-mm polytetrafluoroethylene grafts were used in one and five patients, respectively, for debranching. Endovascular aneurysm repair was performed following debranching procedures as soon as the patients were stabilized. In total, three patients died at the early, mid, and long-term follow-up due to multiorgan failure, pneumonia, and unknown reasons. Conclusion Hybrid repair of thoracoabdominal aneurysms may be an alternative to fenestrated or branched endovascular stent grafts in patients with increased risk factors for open surgical thoracoabdominal aneurysm repair; however, the procedure requires experience and care.","PeriodicalId":54481,"journal":{"name":"Revista Brasileira De Cirurgia Cardiovascular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44424791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Removal of The Mechanical Valve Leaflet Dislocated into The Pulmonary Vein 机械瓣膜小叶脱位进入肺静脉的手术切除
4区 医学 Q3 Medicine Pub Date : 2022-04-18 DOI: 10.21470/1678-9741-2021-0350
D. Zdravković, Igor S Zivkovic, V. Kovacevic, P. Milačić, M. Miličić
Accidental detachment of mechanical valve leaflet during implantation is a rare and potentially serious complication. When the lost leaflet cannot be found by direct visualisation, additional diagnostic procedures are necessary to detect it. Computer tomography is the best detection method, but the patient needs reoperation. We presented a patient in whom the detached leaflet migrated and became trapped into the left inferior pulmonary vein. The computed tomography (CT) scan was used to reveal leaflets, and successful extirpation was performed in the second operation.
机械瓣叶在植入过程中意外脱离是一种罕见且潜在严重的并发症。当丢失的小叶不能通过直接视觉发现时,需要额外的诊断程序来检测它。计算机断层扫描是最好的检测方法,但患者需要再次手术。我们报告了一个患者,其中分离的小叶迁移并被困在左下肺静脉。计算机断层扫描(CT)显示小叶,并在第二次手术中成功切除。
{"title":"Surgical Removal of The Mechanical Valve Leaflet Dislocated into The Pulmonary Vein","authors":"D. Zdravković, Igor S Zivkovic, V. Kovacevic, P. Milačić, M. Miličić","doi":"10.21470/1678-9741-2021-0350","DOIUrl":"https://doi.org/10.21470/1678-9741-2021-0350","url":null,"abstract":"Accidental detachment of mechanical valve leaflet during implantation is a rare and potentially serious complication. When the lost leaflet cannot be found by direct visualisation, additional diagnostic procedures are necessary to detect it. Computer tomography is the best detection method, but the patient needs reoperation. We presented a patient in whom the detached leaflet migrated and became trapped into the left inferior pulmonary vein. The computed tomography (CT) scan was used to reveal leaflets, and successful extirpation was performed in the second operation.","PeriodicalId":54481,"journal":{"name":"Revista Brasileira De Cirurgia Cardiovascular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47656365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selvester Score May Be a Predictor of ICD Therapies in Patients with Non-Ischemic Dilated Cardiomyopathy Selvester评分可能是非缺血性扩张型心肌病患者ICD治疗的预测指标
4区 医学 Q3 Medicine Pub Date : 2022-04-18 DOI: 10.21470/1678-9741-2021-0112
M. Kuyumcu, M. Uzun, Y. Ozen, F. Aksoy, B. A. Uysal, E. Varol
Introduction The benefit of implantable cardioverter-defibrillator (ICD) in patients with non-ischemic dilated cardiomyopathy (DCM) is still an issue under discussion. Studies examining the relationship between ventricular scar tissue and ICD shock with cardiac magnetic resonance (CMR) are promising. CMR studies have shown that ventricular scar tissue size and Selvester score show a correlation. In the light of this information, this study aimed to investigate the potential relationship between Selvester score and ICD therapies. Methods The study included 48 patients who had undergone ICD implantation with a diagnosis of DCM and who had undergone routine 6-month ICD control in outpatient clinic controls between December 2018 and October 2019. Selvester score and other data were compared between patients who received ICD therapy (n=10) and those who did not (n=38). Results Selvester score (P<0.001) was higher in ICD therapy group. Positive correlation was found between ICD shock therapy and Selvester score (P=0.002, r=0.843). Selvester score was detected as an independent predictor for ICD therapy after multiple linear regression analysis (P=0.004). Receiver operating characteristic curve analysis showed that Selvester score (P<0.001) was a significant predictor of ICD therapy. Selvester score cutoff points of 5 for were calculated to estimate ICD therapy, with a sensitivity of 100% and specifity of 81%. Conclusion In our study, it was found that a high Selvester score may be a predictor for ICD therapies in patients with DCM. As an inexpensive and non-invasive method, Selvester score can help in the decision-making in these patients.
引言植入式心律转复除颤器(ICD)对非缺血性扩张型心肌病(DCM)患者的益处仍然是一个正在讨论的问题。用心脏磁共振(CMR)研究心室瘢痕组织和ICD休克之间的关系是有希望的。CMR研究表明,心室瘢痕组织大小和Selvester评分显示出相关性。根据这些信息,本研究旨在调查Selvester评分与ICD治疗之间的潜在关系。方法该研究包括48名在2018年12月至2019年10月期间接受ICD植入并诊断为扩张型心肌病的患者,以及在门诊对照中接受常规6个月ICD控制的患者。比较接受ICD治疗(n=10)和未接受ICD治疗的患者(n=38)的Selvester评分和其他数据。结果ICD治疗组Selvester评分明显高于对照组(P<0.001)。ICD休克治疗与Selvester评分呈正相关(P=0.002,r=0.843)。经多元线性回归分析,Selvester得分是ICD治疗的独立预测因子(P=0.004)。受试者操作特征曲线分析表明,Selvest评分(P<0.001)是ICD治疗显著的预测因子。计算Selvester评分5的临界点来评估ICD治疗,其敏感性为100%,特异性为81%。结论在我们的研究中,发现高Selvester评分可能是DCM患者ICD治疗的预测指标。作为一种廉价且无创的方法,Selvester评分可以帮助这些患者做出决策。
{"title":"Selvester Score May Be a Predictor of ICD Therapies in Patients with Non-Ischemic Dilated Cardiomyopathy","authors":"M. Kuyumcu, M. Uzun, Y. Ozen, F. Aksoy, B. A. Uysal, E. Varol","doi":"10.21470/1678-9741-2021-0112","DOIUrl":"https://doi.org/10.21470/1678-9741-2021-0112","url":null,"abstract":"Introduction The benefit of implantable cardioverter-defibrillator (ICD) in patients with non-ischemic dilated cardiomyopathy (DCM) is still an issue under discussion. Studies examining the relationship between ventricular scar tissue and ICD shock with cardiac magnetic resonance (CMR) are promising. CMR studies have shown that ventricular scar tissue size and Selvester score show a correlation. In the light of this information, this study aimed to investigate the potential relationship between Selvester score and ICD therapies. Methods The study included 48 patients who had undergone ICD implantation with a diagnosis of DCM and who had undergone routine 6-month ICD control in outpatient clinic controls between December 2018 and October 2019. Selvester score and other data were compared between patients who received ICD therapy (n=10) and those who did not (n=38). Results Selvester score (P<0.001) was higher in ICD therapy group. Positive correlation was found between ICD shock therapy and Selvester score (P=0.002, r=0.843). Selvester score was detected as an independent predictor for ICD therapy after multiple linear regression analysis (P=0.004). Receiver operating characteristic curve analysis showed that Selvester score (P<0.001) was a significant predictor of ICD therapy. Selvester score cutoff points of 5 for were calculated to estimate ICD therapy, with a sensitivity of 100% and specifity of 81%. Conclusion In our study, it was found that a high Selvester score may be a predictor for ICD therapies in patients with DCM. As an inexpensive and non-invasive method, Selvester score can help in the decision-making in these patients.","PeriodicalId":54481,"journal":{"name":"Revista Brasileira De Cirurgia Cardiovascular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46638338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgery for Functional Tricuspid Regurgitation in Adult Atrial Septal Defect — An Increasing Subject in a Decreasing Matter 成人房间隔缺损功能性三尖瓣反流的手术治疗-在减少的问题中增加的主题
4区 医学 Q3 Medicine Pub Date : 2022-04-18 DOI: 10.21470/1678-9741-2020-0503
A. Iosifescu, A. Popescu, Toma Andrei Iosifescu, Alina Teodora Timișescu, S. Maximeasa, V. Iliescu
Introduction Functional tricuspid regurgitation (TR) is known to complicate adult atrial septal defect (ASD), but its management is still under debate. We reviewed our experience in ASD surgery, focusing on associated functional TR and its treatment. Methods This retrospective study (2005-2019) included 206 consecutive adult ASD surgical cases without associated valve pathology, except functional TR. Variables were statistically compared on TR classes and surgery-defined groups. Results Mean age of the patients was 40.3±13 years; 19.9% had sinus venosus syndrome. TR severity was directly related to age, pulmonary systolic pressure, right ventricular and tricuspid annulus diameters, and heart failure class. TR ≥ 2 was found in 134 (65%) patients, while TR ≥ 3 in 56 (27.2%) patients. Tricuspid surgery was associated to shunt closure in 66 (32%) patients, almost all through valve repair; indication was directly related to age, right ventricular and tricuspid annulus diameters, and heart failure class ≥ 3. Tricuspid surgery was more efficient than isolated shunt closure in decreasing TR (79±23% vs. 36±26%; P=1.8 E-18). Device closure availability (last four years of the study) was associated with 1/3 reduction of surgical cases but increased the share of cases with TR>2 (> 51% vs. < 31%; P<0.05). Conclusion In the era of device closure, surgery for adult ASD is less frequent, but the share of significant TR cases is in net increase. To avoid long-term postoperative TR, we plead for valve repair in all patients with severe TR and for considering repair in moderate TR at risk of persistence.
引言功能性三尖瓣反流(TR)是已知的使成人房间隔缺损(ASD)复杂化的疾病,但其治疗仍存在争议。我们回顾了我们在ASD手术中的经验,重点关注相关的功能性TR及其治疗。方法这项回顾性研究(2005-2019)包括206例连续的成人ASD手术病例,除功能性TR外,无相关瓣膜病理。对TR类别和手术定义组的变量进行统计比较。结果患者平均年龄40.3±13岁;19.9%患有静脉窦综合征。TR的严重程度与年龄、肺收缩压、右心室和三尖瓣环直径以及心力衰竭分级直接相关。TR≥2者134例(65%),TR≥3者56例(27.2%)。66名(32%)患者的三尖瓣手术与分流关闭相关,几乎全部通过瓣膜修复;适应症与年龄、右心室和三尖瓣环直径、心力衰竭分级≥3直接相关。在降低TR方面,三尖瓣手术比单独的分流闭合更有效(79±23%对36±26%;P=1.8E-18)。器械闭合可用性(研究的最后四年)与手术病例减少1/3有关,但TR>2的病例比例增加(>51%对<31%;P<0.05)。结论在器械闭合时代,成人ASD的手术频率较低,但显著TR病例的比例净增加。为了避免术后长期TR,我们呼吁所有严重TR患者进行瓣膜修复,并考虑对有持续风险的中度TR进行修复。
{"title":"Surgery for Functional Tricuspid Regurgitation in Adult Atrial Septal Defect — An Increasing Subject in a Decreasing Matter","authors":"A. Iosifescu, A. Popescu, Toma Andrei Iosifescu, Alina Teodora Timișescu, S. Maximeasa, V. Iliescu","doi":"10.21470/1678-9741-2020-0503","DOIUrl":"https://doi.org/10.21470/1678-9741-2020-0503","url":null,"abstract":"Introduction Functional tricuspid regurgitation (TR) is known to complicate adult atrial septal defect (ASD), but its management is still under debate. We reviewed our experience in ASD surgery, focusing on associated functional TR and its treatment. Methods This retrospective study (2005-2019) included 206 consecutive adult ASD surgical cases without associated valve pathology, except functional TR. Variables were statistically compared on TR classes and surgery-defined groups. Results Mean age of the patients was 40.3±13 years; 19.9% had sinus venosus syndrome. TR severity was directly related to age, pulmonary systolic pressure, right ventricular and tricuspid annulus diameters, and heart failure class. TR ≥ 2 was found in 134 (65%) patients, while TR ≥ 3 in 56 (27.2%) patients. Tricuspid surgery was associated to shunt closure in 66 (32%) patients, almost all through valve repair; indication was directly related to age, right ventricular and tricuspid annulus diameters, and heart failure class ≥ 3. Tricuspid surgery was more efficient than isolated shunt closure in decreasing TR (79±23% vs. 36±26%; P=1.8 E-18). Device closure availability (last four years of the study) was associated with 1/3 reduction of surgical cases but increased the share of cases with TR>2 (> 51% vs. < 31%; P<0.05). Conclusion In the era of device closure, surgery for adult ASD is less frequent, but the share of significant TR cases is in net increase. To avoid long-term postoperative TR, we plead for valve repair in all patients with severe TR and for considering repair in moderate TR at risk of persistence.","PeriodicalId":54481,"journal":{"name":"Revista Brasileira De Cirurgia Cardiovascular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48675296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To Treat or Not to Treat? This Is the Question… About the Incidental Finding of Double Sinus of Valsalva Aneurysm in A 91-Year-Old Woman 治疗还是不治疗?这是一个关于偶然发现的双窦Valsalva动脉瘤在91岁妇女的问题
4区 医学 Q3 Medicine Pub Date : 2022-04-18 DOI: 10.21470/1678-9741-2021-0403
L. Marco, G. Comentale, M. Bruno, V. Lanzillotti, M. Colletta, V. Russo, D. Pacini, G. Casella
Sinus of Valsalva aneurysm is a very uncommon clinical finding and often requires emergency surgery due to its high risk of rupture. This educational text reports the case of a 91-year-old Italian women who was incidentally discovered to have a huge double aneurysm of the sinuses of Valsalva.
Valsalva动脉瘤窦是一种非常罕见的临床发现,由于其破裂的高风险,经常需要紧急手术。这个教育文本报告的情况下,一个91岁的意大利妇女谁偶然发现有一个巨大的双动脉瘤的鼻窦Valsalva。
{"title":"To Treat or Not to Treat? This Is the Question… About the Incidental Finding of Double Sinus of Valsalva Aneurysm in A 91-Year-Old Woman","authors":"L. Marco, G. Comentale, M. Bruno, V. Lanzillotti, M. Colletta, V. Russo, D. Pacini, G. Casella","doi":"10.21470/1678-9741-2021-0403","DOIUrl":"https://doi.org/10.21470/1678-9741-2021-0403","url":null,"abstract":"Sinus of Valsalva aneurysm is a very uncommon clinical finding and often requires emergency surgery due to its high risk of rupture. This educational text reports the case of a 91-year-old Italian women who was incidentally discovered to have a huge double aneurysm of the sinuses of Valsalva.","PeriodicalId":54481,"journal":{"name":"Revista Brasileira De Cirurgia Cardiovascular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43643312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Revista Brasileira De Cirurgia Cardiovascular
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