Orthopaedics & Traumatology-Surgery & Research最新文献

Background: Younger patients who undergo total hip arthroplasty (THA) often exhibit higher activity and functionality. After the 1 st generation highly cross-linked polyethylene liners (HXLPE), there was advancement with the development of the 2nd generation Vitamin E-infused highly cross-linked polyethylene (VEPE) for polyethylene liners. However, there is limited research comparing these advancements, especially in younger patients. Therefore we did a retrospective comparative study aiming to determine: 1) the wear rate, 2) survivorships of the 1 st and 2nd generations of HXLPE in patients aged <30 years who underwent THA.

Hypothesis: There is no difference between first and second generation of highly cross-linked polyethylene regarding lower linear and volumetric wear rates.

Methods: From 2008-2019, we selected 121 patients, 150 hips of ceramic-polyethylene articulation THA in patients aged <30 years at least 5 years of follow-up. These patients were divided into two groups: 80 hips for 1 st generation HXLPE and 70 hips for 2nd generation VEPE. Both groups had no significant difference regarding age, gender, BMI, and the indication for THA. We compared the wear rate of polyethylene in both groups using PolyWare 7 software and assessed the 5-year THA survival rate.

Results: In both groups, there was no significant difference in linear and volumetric wear, as measured using PolyWare 7 software. Linear wear rate was 0.0365 ± 0.0187 mm/yr in the 1 st generation HXLPE and 0.0351 ± 0.0171 mm/yr in the 2nd generation VEPE groups. Volumetric wear rate was 20.848 ± 11.319 mm³/yr in the 1 st generation HXLPE and 18.679 ± 7.933 mm³/yr in the 2nd generation VEPE groups. The overall 5-year survival rate post-surgery was 98.7%; no significant difference in the survival rates between the 1 st and 2nd generation groups (98.8 and 98.6% for the 1 st and 2nd generation groups).

Conclusion: In young patients, there was no significant difference in the wear rates between the 1 st generation HXLPE and 2nd generation VEPE when using ceramic-polyethylene bearing surfaces. Based on the analysis of complications, survival rates, and functional scores post-surgery, the results of THA using ceramic-any HXLPE articulation were satisfactory in patients aged <30 years.

Level of evidence: III; Case-control study.

Introduction: The impact of enhanced rehabilitation after surgery (ERAS) on treatment quality and safety has been little reported. The present study aimed to analyze rates of complications and readmission in the 3 months after total knee or hip replacement (TKR, THR) following an ERAS protocol, by stratifying patients according to surgery time.

Methods: A single-center multi-surgeon retrospective observational study was conducted on prospectively collected data. 1,299 THRs and 407 TKRs performed in first line between October 2018 and November 2022 were included. Patients were grouped according to surgery time: group A, ≤2 h; group B, >2 h. Data for perioperative results, surgery time, hospital length of stay, complications and readmissions within 90 days were collected.

Results: 1,235 THR patients (95%) were in group A and 64 (5.0%) in group B. The complications rate in THR was 0.8% overall: 0.4% in group A, versus 9.4% in group B (p < 0.0001). The readmission rate was 1.2%: 1.2% in group A, versus 6.3% in group B (p = 0.006). Mean hospital length of stay was 2.7 ± 1.4 days (range, 0-9). Longer surgery time correlated with longer stay (p = 0.033), later mobilization (p < 0.0001) and higher ASA score (p = 0.01). 358 TKR patients (88%) were in group A and 49 (12%) in group B. The complications rate in TKR was 0.5% overall, with no significant difference between groups. The readmission rate was 1%, with no significant difference between groups. Mean hospital stay was 3.2 ± 1.5 days (range, 1-9). Longer surgery time correlated with younger age (p < 0.0001) and later mobilization (p = 0.0001).

Conclusion: Longer surgery time was associated with a slightly higher complications rate and longer hospital stay in case of ERAS after THR or TKR. However, ERAS ensured treatment safety, with <4 days' mean hospital length of stay in a university hospital.

Level of evidence: IV.

Introduction: The aim of our study was to describe a new anteromedial approach that allows exposure of the anteromedial facet of the coronoid process and to characterize the position of the median nerve's motor branches relative to this approach in relation to elbow positioning.

Material and methods: We performed 16 anteromedial approaches on fresh anatomical specimens. The minimum distance between the medial edge of the trochlea and the second branch of the median nerve was measured in three elbow positions: forearm in supination with the elbow extended, forearm in pronation with the elbow extended, and forearm in supination with the elbow flexed at 90 °. The distance between the joint space and the origin of the first two motor branches of the median nerve was then measured with the elbow extended.

Results: The mean distance between the second motor branch of the median nerve and the medial edge of the trochlea was 13 mm ± 3 mm with the elbow extended and forearm supinated; 5 mm ± 3 mm with the elbow extended and forearm pronated; and 11 mm ± 4 mm with the elbow flexed at 90 ° and forearm supinated. There was a significant difference in distance between the measurement in the pronated position and the two measurements in the supinated positions. However, there was no significant difference between the measurement with the elbow flexed in supination and the elbow extended in supination (p < 0.06).

Conclusion: The subpronator approach is a reproducible and reliable approach that allows exposure of the tip of the coronoid process and its anteromedial facet, up to the insertion of the anterior bundle of the medial collateral ligament on the sublime tubercle. We have shown that placing the forearm in supination moves the motor branches at risk of injury away from the surgical site.

Level of evidence: V.

Anterior tibial tuberosity osteotomy is a well-described therapeutic option for the treatment of patellar instability. External torsion of the anterior tibial tuberosity can be one of several factors that adversely affect the patellofemoral joint and its stability. The Anterior Tibial Tubercle Internal Torsion Osteotomy (ATTITO) allows the correction of excessive external torsion of the tibial tuberosity in a safe and reproducible manner. LEVEL OF EVIDENCE: V.

Introduction: Although there is no consensus in the literature, it is believed that the Soong classification system and fracture pattern are risk factors for plate removal in distal radius fractures.

Hypothesis: The aim of this large-scale study was to evaluate the relationship between Soong classification, fracture pattern, and implant removal in distal radius fractures.

Materials and methods: We retrospectively evaluated 795 patients who underwent surgery using a volar locking plate for distal radius fractures at our clinic between 2005 and 2022. The patients were divided into two groups: implant removed, and implant retained. The groups were examined for demographic data, follow-up periods, fracture classifications, and radiological parameters. Additionally, the patients were divided into groups and compared according to the Soong classification, which was determined according to implant placement. Indications for implant removal were also included in this study, and their relationships with other parameters were evaluated.

Results: A total of 123 and 672 patients were included in the implant removed and retained groups, respectively. The average age of the implant removed group was significantly lower (p = 0.005). There were no significant differences between the two groups in terms of fracture classification or other radiological parameters. In the implant removed group, the rate of grade 2, according to the Soong classification, was statistically higher than that in the other groups (p = 0.019). Flexor tenosynovitis was the most common reason for implant removal.

Conclusion: The Soong classification system is an important risk factor associated with implant removal. This risk may increase, particularly among young patients. Surgeons should consider placing the distal radius locking plate as proximally as possible to reduce the frequency of implant removal.

Level of evidence: III; retrospective comparative study.

Introduction: The indications for total knee arthroplasty (TKA) are expanding to include younger and more active patients. Several recent studies have warned of a higher revision rate and lower patient satisfaction in younger patients. The aim of this study was to assess the survival of TKAs in patients under the age of 55 and to determine the risk factors for revision and complications.

Hypothesis: The hypothesis was that TKA survival in patients under 55 years of age is greater than 90% at 10 years.

Materials and methods: This work was a single-center retrospective study. All patients under 55 years of age with first-line TKA between 2006 and 2016 were included. The survival rate was calculated with TKA failure as the primary outcome, which was defined as revision surgery regardless of cause. The Kaplan‒Meier method was used to meet the primary objective.

Results: A total of 168 patients (median age 52 years) with 193 TKAs were included. The mean follow-up was 7.9 years, and 24 cases of failure were identified. The 10-year survival rate was 86.6% (95% CI [81.1-92.2]). The mean time to failure was 4.1 years. Mechanical loosening and infection were the main causes of failure. Body mass index (BMI) appeared to increase the risk of revision (p < 0.01). TKAs with a third condyle were less strongly associated with the risk of revision and complications (p < 0.05), as was the presence of a tibial keel (p < 0.05). TKAs with posttraumatic gonarthrosis (p = 0.066), osteonecrosis (p < 0.05) and sequelae of septic arthritis (p < 0.05) appeared to be the most at risk of revision.

Conclusion: This hypothesis has not been verified, and TKA in patients under 55 years of age appears to have a higher revision rate than in the general population. The indication for TKA in these patients remains a reliable option, but certain risk factors must be considered.

Level of evidence: IV; retrospective study.

Introduction: Spinopelvic kinematics, reflected by the change in spinopelvic tilt (ΔSPT) from a standing position to a flexed seated position, has been associated with the risk of prosthetic impingement and hip dislocation. Some studies have suggested changes in spinopelvic mobility after total hip arthroplasty (THA), but none have explored changes in mobility in the first three months following THA using a direct anterior approach.

Hypothesis: Our hypothesis was that changes in spinopelvic mobility occur in the first 3 months postoperatively, leading to increased hip mobility and increased spinopelvic kinematic abnormalities.

Methods: This retrospective analysis of a consecutive series included 109 patients treated with primary anterior THA by a single senior surgeon. Lateral radiographs taken in standing and flexed seated positions before and three months after surgery were examined to analyze ΔSPT, pelvic femoral angle (PFA), lumbar lordosis (LL), and abnormal spinopelvic mobility (ΔSPT ≥20 °). Secondary objectives included examining the relationship between changes in lumbar flexion and hip flexion, and then analyzing preoperative spinopelvic parameters involved in postoperative pelvic mobility changes.

Results: Between the two periods of analysis, the ΔSPT increased on average by 9.53 ° (-34.4/50.3 °), the ΔPFA increased by 7.68 ° (-74/49 °), and lumbar flexion (ΔLL) decreased by 4.26 ° (-20.8/26 °). The rate of ΔSPT ≥20 ° was 22.9% before the operation and 47.7% after the operation (OR = 8.98; CI [2.82; 28.56]; p < 0.001). A strong positive correlation was found between changes in ΔSPT and ΔPFA (ρ = 0.76; r² = 0.574; p < 0.001) and no correlation between changes in ΔSPT and ΔLL (ρ=-0.019; r² = 0.005; p = 0.842). The multivariate analysis demonstrated independent predictors of change in ΔSPT were body mass index (BMI, β = -0.59, [-1.15; -0.03], p = 0.0386), ΔPFA (β = -0.46, [-0.59; -0.34], p < 0.001), and ΔLL (β = -0.36, [-0.53; -0.19], p < 0.001). No dislocation was observed.

Conclusions: Spinopelvic mobility changes occur early on, within 3 months, after anterior THA. Patients with preoperative lumbar stiffness, associated with a stiff hip and lower BMI, should prompt surgeons to the risk of worsening spinopelvic kinematic abnormalities postoperatively.

Level of evidence: IV; retrospective study.

Introduction: A poorly treated acute ankle sprain can rapidly progress to chronic instability, with varying degrees of disability secondary to weakness of the ankle stabilizers. The aim of our study was to evaluate functional scores and physical tests in the assessment of eversion and proprioception deficits after non-surgical treatment of chronic ankle instability. Our hypothesis was that these functional scores and physical tests are suitable and sufficient for assessing the functional aspect of an unstable ankle.

Material and method: This was a prospective, single-center study of patients managed for chronic ankle instability between November 2020 and November 2021. An ankle assessment was performed using two functional scores, the Foot Ankle Ability Measurement (FAAM) and the Ankle Ligament Reconstruction - Return to Sport after Injury (ALR-RSI), as well as two validated physical tests (Y-Balance Test and Side Hope Test). An objective (quantified) assessment of stabilizer muscle strength and proprioception was carried out using a connected device (Myolux™ Medik e-volution).

Results: At last recoil, twenty-eight unstable ankles were included. Only the ALR-RSI score correlated strongly with Myolux™ assessment of eversion strength (Rho ()ρ = 0.7; p < 0.001), and proprioception (Rho ()ρ = 0.8; p < 0.001). FAAM and physical tests were not or only very moderately correlated with Myolux™ assessments.

Discussion: In the absence of the Myolux™ test, the ALR-RSI score seemed the most suitable functional assessment of an unstable ankle in contrast to the FAAM score and the physical examinations Y-Balance Test and Side Hope Test.

Level of evidence: IV; prospective study.

Background: Synovial sarcoma (SS) is classified as an aggressive high-grade soft tissue sarcoma that predominantly affects the extremities. Despite its prevalence in the extremities (up to 80%), diagnostic and treatment challenges persist. This study aims to address these challenges by providing a comprehensive analysis of SS in extremities, focusing on diagnostic accuracy and treatment outcomes. The central questions of this study are: What are the diagnostic and treatment challenges associated with SS? How do tumor volume and histologic subtype influence prognosis? What role do immunohistochemistry and genetic markers play in SS diagnosis and management?

Hypothesis: We hypothesize that larger tumor volume and poor histologic differentiation are associated with worse survival outcomes in patients with SS.

Patients and methods: This retrospective study analyzed data from 63 patients diagnosed with SS between 2005 and 2020 at a single center. Patients with complete records of pathology, radiology, and surgery, and a minimum follow-up of 12 months were included. Tumor characteristics, treatment modalities, and follow-up data were reviewed.

Results: The study included 63 patients and 65 tumors. The mean age was 38 ± 17 years. There were 31 females (49%) and 32 males (51%). SS predominantly affected the extremities (n = 63, 97%), especially the lower limbs (n = 49, 75%). Tumor volume, with a mean of 110 ± 176 cm³, was a significant factor, with tumors >30 cm³ associated with higher rates of metastasis (p = 0,006) and reduced survival (p = 0,027). Histologically, 25 (38%) were monophasic, 24 (37%) were biphasic, and 16 (25%) were poorly differentiated, with poorer survival linked to poorly differentiated subtypes. Immunohistochemistry showed high positivity rates for Bcl-2 (89%, 17/19), EMA (88%, 52/59), and TLE1 (87%, 13/15). SS18-SSX fusion gene detected in 73% of cases (8/11). Metastasis occurred in 27 (42%) patients and recurrence in 24 (37%). 15 (23%) patients died from the disease.

Discussion: Accurate diagnosis of SS is crucial for effective management. Clinicians should be aware of negative predictive factors, including tumor volume >30 cm³ and poor histologic differentiation, when making treatment decisions. The study highlights the importance of extended follow-up due to the risk of late recurrence.

Level of evidence: IV.

Introduction: Primary total knee arthroplasty (TKA) has shown excellent results in the treatment of osteoarthritis, and its indications have now been extended to younger patients of working age. Few articles in the literature have studied the return to work of young subjects, and no specific studies have been conducted in France. Therefore, we carried out a retrospective study to 1) investigate the rate and delay of return to work after primary TKA in a population under 55 years of age and 2) identify factors influencing early return to work before 3 months, the period usually used as the duration of initial work stoppage (TS).

Hypothesis: The hypothesis of this study was that the rate and time to return to work were similar to those of other Western studies.

Materials and methods: This was a single-center retrospective study including all patients under 55 years of age who underwent primary TKA between 2010 and 2019, regardless of their professional status. A questionnaire collected all socioeconomic and medical information, time to return to work, and factors influencing it. Our population consisted of 223 TKAs (201 patients), with a participation rate of 64%. Among 129 patients, with a mean age of 50.3 ± 4.6 years [29-55], 109 were working (84%).

Results: Ninety-four of 109 patients (86.2%) returned to work after surgery at a mean time of 17.3 ± 10.6 weeks [12-24]. Previous hip or knee prosthetic surgery had a significant negative influence on the rate of return to work (OR 0.08; 95% CI [0.008; 0.7] [p = 0.027]). Manual workers returned to work significantly earlier (OR 8.2; 95% CI [1.6; 51.4] [p = 0.017]). A total of 56 patients (43.4%) were off work preoperatively, for a mean time of 16.7 ± 17.8 weeks [4,13-24], and 49 of these patients returned to work (87.5%) at a mean time of 18.7 ± 11 weeks [12-24] compared with patients who did not receive a preoperative work stoppage (WK) (p = 0.7).

Conclusion: The hypothesis was only partially confirmed. Compared with patients in other Western countries, French patients under 55 years of age who underwent primary TKA surgery appeared to return to work at the same rate but with a longer delay. Patients on WT prior to surgery were more likely to return to work after the operation, although this difference did not reach the significance threshold.

Level of evidence iv: Retrospective observational study.