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Utilisation of in-person and telehealth care among US adults with loneliness and social isolation. 孤独感和社会孤立的美国成年人对面对面和远程医疗的利用。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1136/jech-2025-223917
Sungchul Park, Jiani Yu, Hye-Young Jung

Background: Telehealth has become a critical tool for improving access to care among populations facing physical barriers to in-person care. However, its potential role in delivering care to adults with social barriers remains underexplored. We examined whether adults with loneliness or social isolation are more likely to use telehealth care versus in-person care compared to adults without loneliness or social isolation.

Methods: This cross-sectional study analysed data for US adults in the 2021 Medical Expenditure Panel Survey. Loneliness and social isolation were measured using the UCLA Loneliness Scale and the Berkman-Syme Social Network Index. Three indicators of healthcare utilisation were used as outcomes: in-person care only, telehealth care only and a combination of both.

Results: Among adults experiencing loneliness and social isolation, the likelihood of using only in-person care was lower by 4.1 (95% CI -6.1 to -2.1) and 2.8 (95% CI -5 to -0.6) percentage points. In contrast, the likelihood of using only telehealth care was higher by 2.6 (1.1-4.2) and 5.4 (3.9-6.9). The likelihood of using both in-person and telehealth care was also higher by 2.3 (0.7-3.9) and 5.2 (3.7-6.7), but telehealth was used more frequently than in-person care. Furthermore, telehealth utilisation for mental health services was higher among adults experiencing loneliness or social isolation.

Conclusion: Compared with adults who are not lonely or socially isolated, adults experiencing loneliness and social isolation are more likely to use telehealth and less likely to use in-person care. Telehealth may serve as a viable alternative for individuals facing social challenges in accessing in-person services.

背景:远程医疗已成为改善面临面对面护理物理障碍的人群获得护理的关键工具。然而,它在为有社会障碍的成年人提供护理方面的潜在作用仍未得到充分探索。我们研究了与没有孤独或社会隔离的成年人相比,孤独或社会隔离的成年人是否更有可能使用远程医疗服务而不是面对面护理。方法:本横断面研究分析了2021年医疗支出小组调查中美国成年人的数据。孤独感和社会隔离使用加州大学洛杉矶分校孤独感量表和伯克曼-赛姆社会网络指数进行测量。医疗保健利用的三个指标被用作结果:仅现场护理、仅远程保健以及两者的结合。结果:在经历孤独和社会隔离的成年人中,仅使用面对面护理的可能性降低了4.1 (95% CI -6.1至-2.1)和2.8 (95% CI -5至-0.6)个百分点。相比之下,仅使用远程保健的可能性高出2.6(1.1-4.2)和5.4(3.9-6.9)。同时使用现场医疗和远程医疗的可能性分别为2.3(0.7-3.9)和5.2(3.7-6.7),但使用远程医疗的频率高于现场医疗。此外,在感到孤独或社会孤立的成年人中,远程保健对心理健康服务的利用程度较高。结论:与没有孤独或社会孤立的成年人相比,经历孤独和社会孤立的成年人更倾向于使用远程医疗,而不太可能使用面对面护理。对于在获得面对面服务方面面临社会挑战的个人来说,远程保健可以作为一种可行的替代方案。
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引用次数: 0
Co-designed and co-delivered place-based community interventions to reduce inequity in early initiation of antenatal care: findings from the cluster randomised controlled community REACH trial. 共同设计和共同提供基于地方的社区干预措施,以减少早期产前保健的不平等:来自集群随机对照社区REACH试验的结果。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-11 DOI: 10.1136/jech-2024-223248
Angela Harden, Meg Wiggins, Lorna Sweeny, Mary Sawtell, Cathryn Salisbury, Thomas Hamborg, Sandra Eldridge, Lauren Greenberg, Rachael Maree Hunter, Ekaterina Bordea, Christine McCourt, Bethan Hatherall, Gail Findlay, Adrian Renton, Ruth Ajayi, Ceri Durham, Adewale Adeyemo, Belinda Harvey, Kade Mondeh, Logan VanLessen

Background: Early initiation of antenatal care provides timely screening, advice and support. Inequities in early care initiation exist in high-income countries, but there is scant evidence on effective interventions. The community REACH (Research for Equitable Antenatal Care and Health) trial aimed to assess the effectiveness of co-produced place-based interventions to strengthen community support for early care initiation.

Methods: Matched-pair cluster randomised trial in socially disadvantaged and ethnically diverse areas in England. Electoral wards with low rates of early care initiation were matched and randomly allocated to intervention or control (usual care) (n=10 pairs). Following a 3-month co-design phase, community organisations and volunteers in intervention sites conducted targeted outreach activities over 6 months. The primary outcome was initiation of antenatal care by the 12th completed week of pregnancy.

Results: There was no evidence of a difference in the primary outcome (OR 1.07, 95% CI 0.89 to 1.28). There were also no statistically significant differences in rates of emergency caesarean, preterm birth, low birth weight, smoking or breastfeeding. There was a higher rate of care initiation by 10 weeks and fewer antenatal admissions in the intervention arm during the intervention period, although differences were not sustained after it finished.

Conclusion: This rigorous evaluation found a limited impact of short-term place-based interventions to strengthen community support for early initiation of antenatal care. Future initiatives may benefit from embedding in integrated health and care structures to ensure sufficient time and resources for mobilisation of community assets and focusing on smaller 'hyper-local' neighbourhoods. Actions to tackle wider structural and organisational barriers are also needed.

Trial registration number: ISRCTN registry: registration number 63066975. Registered on 18 August 2015.

背景:早期开展产前保健可提供及时的筛查、建议和支持。高收入国家在早期护理方面存在不公平现象,但缺乏有效干预措施的证据。社区公平产前护理和健康研究(REACH)试验旨在评估共同制定的基于地方的干预措施的有效性,以加强社区对早期护理启动的支持。方法:在英国社会弱势和种族多样化地区进行配对随机分组试验。早期护理开始率低的选举病房被匹配并随机分配到干预或控制(常规护理)(n=10对)。经过3个月的共同设计阶段,社区组织和志愿者在干预地点进行了为期6个月的有针对性的外展活动。主要结局是在怀孕第12周开始产前护理。结果:没有证据表明主要结局有差异(OR 1.07, 95% CI 0.89至1.28)。在紧急剖腹产、早产、低出生体重、吸烟或母乳喂养方面也没有统计学上的显著差异。在干预期间,干预组在10周内的护理开始率较高,产前入院率较低,尽管在干预结束后差异并未持续。结论:这项严格的评估发现,短期的基于地点的干预措施对加强社区对早期开始产前保健的支持的影响有限。今后的举措可能受益于纳入综合保健结构,以确保有足够的时间和资源来调动社区资产,并侧重于较小的“超地方性”社区。还需要采取行动解决更广泛的结构性和组织性障碍。试验注册号:ISRCTN注册号:注册号63066975。于2015年8月18日注册。
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引用次数: 0
Does the 'right to request' flexible work policy influence men's and women's uptake of flexible working and well-being: findings from the UK Household Longitudinal Study. “要求灵活工作的权利”政策是否会影响男性和女性对灵活工作和幸福的接受:来自英国家庭纵向研究的发现。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-10 DOI: 10.1136/jech-2025-224166
Baowen Xue, Heejung Chung, Ran Gu, Anne McMunn

Background: The 'right to request' flexible working policy has been gradually extended and, by 2014, extended to cover all workers with at least 26 weeks of continuous employment. The impact of these policy changes is unclear. This research aims to assess the effects of the 2014 policy reform on the uptake of flexible working and its impact on health and well-being, focusing on gender differences.

Methods: Data were drawn from waves 2, 4, 6, 8 and 10 of the UK Household Longitudinal Study (2010-2020). We employed a doubly robust difference-in-differences method to estimate the average treatment effects on the treated of the 2014 policy reform. This analysis examined the effects on the uptake of flexible working, mental and physical health, and satisfaction with life, job and leisure.

Findings: The 2014 policy reform increased women's uptake of reduced hours work arrangements, with the effect growing stronger over time. However, no increase in uptake was observed among men. No strong effects were found for flexitime or teleworking arrangements for either men or women. Additionally, the policy reform resulted in a reduction in psychological distress and improved life satisfaction among women.

Conclusions: The reduction in women's psychological distress and improved life satisfaction might be partly explained by the increased women's uptake of reduced hours arrangements, which may have enabled women to better meet their family care demands. However, even the gender-neutral policies on flexible working may inadvertently exacerbate gender inequalities in labour force participation by pushing women more into part-time work.

背景:弹性工作政策的“请求权”已逐步扩大,到2014年,扩大到覆盖所有连续工作至少26周的工人。这些政策变化的影响尚不清楚。本研究旨在评估2014年政策改革对采用灵活工作制的影响及其对健康和福祉的影响,重点关注性别差异。方法:数据来自英国家庭纵向研究(2010-2020)的第2、4、6、8和10波。我们采用双稳健差分法估计2014年政策改革的平均治疗效果。这项分析考察了对弹性工作、身心健康以及对生活、工作和休闲的满意度的影响。研究结果:2014年的政策改革提高了女性对减少工作时间安排的接受程度,并且随着时间的推移,效果越来越强。然而,在男性中没有观察到摄取增加。无论是对男性还是女性来说,弹性工作时间或远程工作安排都没有发现明显的影响。此外,政策改革减少了妇女的心理痛苦,提高了她们的生活满意度。结论:女性心理困扰的减少和生活满意度的提高可能部分解释为女性越来越多地接受减少的工作时间安排,这可能使女性更好地满足家庭照顾需求。然而,即使是关于灵活工作的中性政策,也可能在不经意间加剧劳动力参与方面的性别不平等,迫使女性更多地从事兼职工作。
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引用次数: 0
Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition. 生活方式能否解释社会经济地位与癌症和心脏代谢疾病的多重发病率之间的关系?应用于欧洲癌症与营养前瞻性调查的中介分析。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-10 DOI: 10.1136/jech-2025-224476
Luca Manfredi, Federica Buscema, Maria Teresa Giraudo, Barbara Sodano, Lisa Padroni, Cinzia Destefanis, Heinz Freisling, Pietro Ferrari, Giulia Cesaroni, Sergio Uzzau, Matthias B Schulze, Calogero Saieva, Rosario Tumino, Elisabete Weiderpass, Komodo Matta, Salvatore Vaccarella, Marcela Guevara, Jytte Halkjær, Anne Tjønneland, Marta Crous-Bou, Verena Katzke, Toktam Pour, Salvatore Panico, Valeria Pala, Ioanna Tzoulaki, Sandar Tin Tin, Christina C Dahm, MªDolores Chirlaque, Carlotta Sacerdote, Fulvio Ricceri

Background: Multimorbidity is socially patterned, with lower socioeconomic position (SEP) linked to higher risk. We examined whether a Healthy Lifestyle Index (HLI) mediates the SEP-multimorbidity association and whether pathways differ by sex.

Methods: We used data from 244 886 participants in the European Prospective Investigation into Cancer and Nutrition study. HLI was derived from smoking, alcohol consumption, physical activity, body mass index and diet. SEP was categorised into low, medium and high-SEP based on education. Multimorbidity was defined as the coexistence of at least two diseases among cancer, type 2 diabetes and cardiovascular diseases. Logistic regression assessed SEP-HLI association, Cox regression SEP-multimorbidity and HLI-multimorbidity associations. Counterfactual mediation analysis estimated the natural indirect effect (NIE) and pure direct effect (PDE). Analyses were stratified by sex.

Results: Participants from lower SEP categories were older with worse health outcomes. Women had a healthier lifestyle than men across all SEP levels. In men, the hazard ratio of developing multimorbidity was 1.40 (95% CI: 1.26 to 1.54) for those with low SEP compared with high SEP, in women 1.74 (95% CI: 1.52 to 2.00). Comparing low versus high SEP, PDE for men was 1.28 (95% CI: 1.15 to 1.41), NIE was 1.09 (95% CI: 1.07 to 1.11) (proportion mediated (PM)=29%). In women, PDE was 1.65 (95% CI: 1.47 to 1.90), NIE 1.05 (95% CI: 1.03 to 1.06) (PM=11%).

Conclusions: Lifestyle behaviours partly mediated the SEP-multimorbidity association, underscoring the need to integrate considerations of socioeconomic disparities into the planning of lifestyle interventions.

背景:多发病是一种社会模式,低社会经济地位(SEP)与高风险相关。我们研究了健康生活方式指数(HLI)是否介导sep与多发病的关联,以及途径是否因性别而异。方法:我们使用来自244886名欧洲癌症与营养前瞻性调查研究参与者的数据。HLI来源于吸烟、饮酒、体育活动、身体质量指数和饮食。根据教育程度,SEP分为低、中、高三个等级。多病被定义为癌症、2型糖尿病和心血管疾病中至少两种疾病并存。Logistic回归评估SEP-HLI的相关性,Cox回归评估sep -多发病和hli -多发病的相关性。反事实中介分析估计了自然间接效应(NIE)和纯粹直接效应(PDE)。分析按性别分层。结果:低SEP类别的参与者年龄较大,健康状况较差。在所有SEP水平上,女性的生活方式都比男性健康。在男性中,低SEP患者与高SEP患者发生多重疾病的危险比为1.40 (95% CI: 1.26至1.54),女性为1.74 (95% CI: 1.52至2.00)。比较低SEP与高SEP,男性的PDE为1.28 (95% CI: 1.15至1.41),NIE为1.09 (95% CI: 1.07至1.11)(比例介导(PM)=29%)。在女性中,PDE为1.65 (95% CI: 1.47至1.90),NIE为1.05 (95% CI: 1.03至1.06)(PM=11%)。结论:生活方式行为在一定程度上介导了sep与多发病的关联,强调了将社会经济差异纳入生活方式干预计划的必要性。
{"title":"Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition.","authors":"Luca Manfredi, Federica Buscema, Maria Teresa Giraudo, Barbara Sodano, Lisa Padroni, Cinzia Destefanis, Heinz Freisling, Pietro Ferrari, Giulia Cesaroni, Sergio Uzzau, Matthias B Schulze, Calogero Saieva, Rosario Tumino, Elisabete Weiderpass, Komodo Matta, Salvatore Vaccarella, Marcela Guevara, Jytte Halkjær, Anne Tjønneland, Marta Crous-Bou, Verena Katzke, Toktam Pour, Salvatore Panico, Valeria Pala, Ioanna Tzoulaki, Sandar Tin Tin, Christina C Dahm, MªDolores Chirlaque, Carlotta Sacerdote, Fulvio Ricceri","doi":"10.1136/jech-2025-224476","DOIUrl":"10.1136/jech-2025-224476","url":null,"abstract":"<p><strong>Background: </strong>Multimorbidity is socially patterned, with lower socioeconomic position (SEP) linked to higher risk. We examined whether a Healthy Lifestyle Index (HLI) mediates the SEP-multimorbidity association and whether pathways differ by sex.</p><p><strong>Methods: </strong>We used data from 244 886 participants in the European Prospective Investigation into Cancer and Nutrition study. HLI was derived from smoking, alcohol consumption, physical activity, body mass index and diet. SEP was categorised into low, medium and high-SEP based on education. Multimorbidity was defined as the coexistence of at least two diseases among cancer, type 2 diabetes and cardiovascular diseases. Logistic regression assessed SEP-HLI association, Cox regression SEP-multimorbidity and HLI-multimorbidity associations. Counterfactual mediation analysis estimated the natural indirect effect (NIE) and pure direct effect (PDE). Analyses were stratified by sex.</p><p><strong>Results: </strong>Participants from lower SEP categories were older with worse health outcomes. Women had a healthier lifestyle than men across all SEP levels. In men, the hazard ratio of developing multimorbidity was 1.40 (95% CI: 1.26 to 1.54) for those with low SEP compared with high SEP, in women 1.74 (95% CI: 1.52 to 2.00). Comparing low versus high SEP, PDE for men was 1.28 (95% CI: 1.15 to 1.41), NIE was 1.09 (95% CI: 1.07 to 1.11) (proportion mediated (PM)=29%). In women, PDE was 1.65 (95% CI: 1.47 to 1.90), NIE 1.05 (95% CI: 1.03 to 1.06) (PM=11%).</p><p><strong>Conclusions: </strong>Lifestyle behaviours partly mediated the SEP-multimorbidity association, underscoring the need to integrate considerations of socioeconomic disparities into the planning of lifestyle interventions.</p>","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"3-9"},"PeriodicalIF":3.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12703236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survival among patients with cancer after a coalmine fire: analysis of registry data in regional Victoria, Australia. 煤矿火灾后癌症患者的生存率:对澳大利亚维多利亚地区登记数据的分析
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-10 DOI: 10.1136/jech-2025-223952
Tyler J Lane, Pei Yu, Caroline X Gao, Catherine L Smith, Sherene Loi, Natasha Kinsman, Jillian Ikin, Yuming Guo, Malcolm R Sim, Michael J Abramson

Background: In 2014, a bushfire ignited the Hazelwood coalmine in regional Victoria, Australia, shrouding nearby communities in smoke for 6 weeks. In this study, we examined whether survival decreased among people with cancer in smoke-exposed areas.

Methods: We identified cancers diagnosed between January 2009 and February 2014, the start of the coalmine fire, from the Victorian Cancer Registry. Tumours were grouped by location as well as subtypes for breast and lung cancers. Smoke exposure was determined by the daily average of PM2.5 per 10 µg/m3 attributable to the mine fire at Statistical Area level 2. Survival effects were analysed using a Cox proportional hazards frailty model.

Results: There was no detectable effect of fire-related PM2.5 on overall cancer survival. There was weak evidence that fire-related PM2.5 exposure reduced survival among women with breast cancer (HR: 1.18, 95% CI 1.00 to 1.38 per 10 µg/m3 of PM2.5). No other effects were detectable.

Conclusion: We found limited evidence that smoke from the Hazelwood coal mine fire reduced survival among people living with cancer. The association with reduced survival among women with breast cancer may be a chance finding. However, this does not rule out an effect and further analyses should follow when more data become available or following other similar disasters.

背景:2014年,一场丛林大火点燃了澳大利亚维多利亚州地区的Hazelwood煤矿,将附近社区笼罩在烟雾中长达6周。在这项研究中,我们调查了在烟雾暴露区癌症患者的存活率是否会下降。方法:我们从维多利亚癌症登记处(Victorian Cancer Registry)中确定了2009年1月至2014年2月(煤矿火灾开始时)诊断出的癌症。肿瘤按位置以及乳腺癌和肺癌的亚型进行分组。烟雾暴露量由统计区二级矿井火灾导致的PM2.5每10µg/m3日平均值确定。采用Cox比例风险脆弱性模型分析生存效应。结果:与火灾相关的PM2.5对总体癌症生存没有可检测到的影响。有微弱的证据表明,与火灾有关的PM2.5暴露降低了乳腺癌妇女的生存率(每10微克/立方米PM2.5的风险比:1.18,95%可信区间为1.00至1.38)。没有检测到其他影响。结论:我们发现有限的证据表明Hazelwood煤矿火灾产生的烟雾降低了癌症患者的生存率。乳腺癌患者的存活率降低可能是一个偶然的发现。然而,这并不排除影响,当获得更多数据或发生其他类似灾难时,应进行进一步分析。
{"title":"Survival among patients with cancer after a coalmine fire: analysis of registry data in regional Victoria, Australia.","authors":"Tyler J Lane, Pei Yu, Caroline X Gao, Catherine L Smith, Sherene Loi, Natasha Kinsman, Jillian Ikin, Yuming Guo, Malcolm R Sim, Michael J Abramson","doi":"10.1136/jech-2025-223952","DOIUrl":"10.1136/jech-2025-223952","url":null,"abstract":"<p><strong>Background: </strong>In 2014, a bushfire ignited the Hazelwood coalmine in regional Victoria, Australia, shrouding nearby communities in smoke for 6 weeks. In this study, we examined whether survival decreased among people with cancer in smoke-exposed areas.</p><p><strong>Methods: </strong>We identified cancers diagnosed between January 2009 and February 2014, the start of the coalmine fire, from the Victorian Cancer Registry. Tumours were grouped by location as well as subtypes for breast and lung cancers. Smoke exposure was determined by the daily average of PM<sub>2.5</sub> per 10 µg/m<sup>3</sup> attributable to the mine fire at Statistical Area level 2. Survival effects were analysed using a Cox proportional hazards frailty model.</p><p><strong>Results: </strong>There was no detectable effect of fire-related PM<sub>2.5</sub> on overall cancer survival. There was weak evidence that fire-related PM<sub>2.5</sub> exposure reduced survival among women with breast cancer (HR: 1.18, 95% CI 1.00 to 1.38 per 10 µg/m<sup>3</sup> of PM<sub>2.5</sub>). No other effects were detectable.</p><p><strong>Conclusion: </strong>We found limited evidence that smoke from the Hazelwood coal mine fire reduced survival among people living with cancer. The association with reduced survival among women with breast cancer may be a chance finding. However, this does not rule out an effect and further analyses should follow when more data become available or following other similar disasters.</p>","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"41-46"},"PeriodicalIF":3.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145338154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
No diagnosis for poverty. 没有贫困的诊断。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-10 DOI: 10.1136/jech-2025-224585
Dheeraj Sharma
{"title":"No diagnosis for poverty.","authors":"Dheeraj Sharma","doi":"10.1136/jech-2025-224585","DOIUrl":"10.1136/jech-2025-224585","url":null,"abstract":"","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"64"},"PeriodicalIF":3.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mediating role of psychological distress and alcohol use in socioeconomic disparities in deaths of despair: a causal mediation analysis using record linkage data. 心理困扰和酒精使用在绝望死亡的社会经济差异中的中介作用:使用记录关联数据的因果中介分析。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-10 DOI: 10.1136/jech-2025-224372
Aurélie M Lasserre, Yachen Zhu, Carolin Kilian, Laura Llamosas-Falcón, Jurgen Rehm, Charlotte Probst

Background: Deaths of despair - suicide, drug overdose and chronic liver disease mortality - are major contributors to premature mortality in the USA, disproportionately affecting individuals with low socioeconomic status (SES). The mechanisms underlying these disparities, particularly the roles of psychological distress and alcohol use, remain insufficiently understood. We assessed associations of SES, alcohol use and psychological distress with deaths of despair, along with the mediating roles of alcohol use and psychological distress in the SES-deaths of despair association in men and women.

Methods: We linked US National Health Interview Survey data (1997-2018) to mortality records until 31 December 2019 by following 3 11 508 women and 2 42 463 men for 10.5 years. Using counterfactual-based inverse probability-weighted marginal structural models, we decomposed the total effect of SES (education, income) into direct and indirect effects through psychological distress (Kessler-6) and alcohol use (daily consumption). Analyses were sex-stratified and adjusted for marital status, race and ethnicity and survey year.

Results: Severe psychological distress and high alcohol use were each associated with over a threefold increased risk of death of despair. In men, psychological distress and alcohol use mediated up to 16% and 14% of the SES-deaths of despair relationship, respectively. In women, psychological distress mediated up to 20% of the association, while alcohol use did not mediate the relationship.

Conclusion: Low SES, psychological distress and alcohol use are key risk factors for deaths of despair. Intervention targeting mental health and alcohol use, especially through SES-specific and sex-specific approaches, may help reduce inequalities in these preventable causes of death.

背景:绝望死亡——自杀、药物过量和慢性肝病死亡——是美国过早死亡的主要原因,对低社会经济地位(SES)的个体影响尤为严重。这些差异背后的机制,特别是心理困扰和酒精使用的作用,仍然没有得到充分的了解。我们评估了SES、酒精使用和心理困扰与绝望死亡的关联,以及酒精使用和心理困扰在男性和女性SES-绝望死亡关联中的中介作用。方法:我们将美国国家健康访谈调查数据(1997-2018)与死亡率记录联系起来,直到2019年12月31日,对311508名女性和242463名男性进行了10.5年的随访。使用基于反事实的逆概率加权边际结构模型,我们通过心理困扰(Kessler-6)和饮酒(日常消费)将社会经济地位(教育、收入)的总影响分解为直接影响和间接影响。分析按性别分层,并根据婚姻状况、种族和民族以及调查年份进行调整。结果:严重的心理困扰和高酒精使用均与绝望死亡风险增加三倍以上相关。在男性中,心理困扰和酒精使用分别导致16%和14%的ses -绝望关系死亡。在女性中,心理困扰介导了高达20%的关联,而饮酒没有介导这种关系。结论:低社会经济地位、心理困扰和酗酒是绝望死亡的关键危险因素。针对心理健康和酒精使用的干预措施,特别是通过针对ses和性别的方法,可能有助于减少这些可预防的死亡原因中的不平等现象。
{"title":"Mediating role of psychological distress and alcohol use in socioeconomic disparities in deaths of despair: a causal mediation analysis using record linkage data.","authors":"Aurélie M Lasserre, Yachen Zhu, Carolin Kilian, Laura Llamosas-Falcón, Jurgen Rehm, Charlotte Probst","doi":"10.1136/jech-2025-224372","DOIUrl":"10.1136/jech-2025-224372","url":null,"abstract":"<p><strong>Background: </strong>Deaths of despair - suicide, drug overdose and chronic liver disease mortality - are major contributors to premature mortality in the USA, disproportionately affecting individuals with low socioeconomic status (SES). The mechanisms underlying these disparities, particularly the roles of psychological distress and alcohol use, remain insufficiently understood. We assessed associations of SES, alcohol use and psychological distress with deaths of despair, along with the mediating roles of alcohol use and psychological distress in the SES-deaths of despair association in men and women.</p><p><strong>Methods: </strong>We linked US National Health Interview Survey data (1997-2018) to mortality records until 31 December 2019 by following 3 11 508 women and 2 42 463 men for 10.5 years. Using counterfactual-based inverse probability-weighted marginal structural models, we decomposed the total effect of SES (education, income) into direct and indirect effects through psychological distress (Kessler-6) and alcohol use (daily consumption). Analyses were sex-stratified and adjusted for marital status, race and ethnicity and survey year.</p><p><strong>Results: </strong>Severe psychological distress and high alcohol use were each associated with over a threefold increased risk of death of despair. In men, psychological distress and alcohol use mediated up to 16% and 14% of the SES-deaths of despair relationship, respectively. In women, psychological distress mediated up to 20% of the association, while alcohol use did not mediate the relationship.</p><p><strong>Conclusion: </strong>Low SES, psychological distress and alcohol use are key risk factors for deaths of despair. Intervention targeting mental health and alcohol use, especially through SES-specific and sex-specific approaches, may help reduce inequalities in these preventable causes of death.</p>","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"10-16"},"PeriodicalIF":3.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12703257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Childhood bullying involvement and later suicidality: longitudinal analyses from The Danish National Birth Cohort. 儿童期受欺凌与后来的自杀行为:来自丹麦国家出生队列的纵向分析。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-10 DOI: 10.1136/jech-2025-223809
Lauren Marie Campbell-Hansen, Annette Erlangsen, Keith Hawton, Merete Nordentoft, Trine Madsen

Background: Bullying involvement (victim or perpetrator role) in childhood is linked to later suicidality. However, findings are inconsistent, and sex may be a moderator. We investigated whether childhood bullying involvement was associated with suicidality in adolescence, and whether this association varied by sex.

Methods: Childhood bullying involvement was collected from self-reports of children and parents during the 11-year follow-up of the Danish National Birth Cohorts (DNBC). Data on suicidal ideation (SI) and suicide attempts (SA) from the 18-year follow-up were supplemented with hospital records of SA from the National Patient Register. Associations were estimated using multinomial logistic regressions, while inverse probability weighting accounted for socioeconomic-related selection bias.

Results: 11 705 boys and 17 292 girls were included. Adolescent boys exposed to bullying had increased risks of SI (adjusted relative risk ratio (aRRR): 1.6; 95% CI: 1.4 to 1.8) and SA (aRRR: 2.8; 95% CI: 2.0 to 3.8), while no increased risk was found among those who were perpetrators of bullying vs non-involved peers. Girl victims had increased risks (aRRR) of SI and SA of 1.6 (95% CI: 1.5 to 1.7) and 2.9 (95% CI: 2.5 to 3.5), respectively. Girl perpetrators had an increased risk of SA (aRRR: 2.3; 95% CI: 1.5 to 3.6). Sex significantly moderated the association between perpetration role and suicidality.

Conclusion: Childhood bullying was associated with a higher risk of suicidality during adolescence. Girl, but not boy, perpetrators had increased risk of SI and SA. These findings emphasise the importance of preventive interventions targeting bullying in childhood and its long-term effects, including possible differences in policies for boys and girls.

背景:童年时期的欺凌行为(受害者或加害者角色)与后来的自杀行为有关。然而,研究结果并不一致,性别可能是一个调节因素。我们调查了儿童期受欺凌是否与青春期自杀有关,以及这种联系是否因性别而异。方法:收集丹麦国家出生队列(DNBC) 11年随访期间儿童和父母的自我报告。来自18年随访的自杀意念(SI)和自杀企图(SA)数据辅以来自国家患者登记册的自杀未遂医院记录。使用多项逻辑回归估计关联,而逆概率加权解释了与社会经济相关的选择偏差。结果:共纳入男生11 705人,女生17 292人。暴露于欺凌的青春期男孩的SI风险增加(调整相对风险比(aRRR): 1.6;95% CI: 1.4至1.8)和SA (aRRR: 2.8; 95% CI: 2.0至3.8),而在欺凌行为的肇事者与未参与欺凌的同龄人中,没有发现风险增加。女孩受害者的SI和SA风险(aRRR)分别增加了1.6 (95% CI: 1.5至1.7)和2.9 (95% CI: 2.5至3.5)。女孩犯罪者患SA的风险增加(aRRR: 2.3; 95% CI: 1.5 - 3.6)。性显著调节了犯罪角色与自杀行为之间的关系。结论:童年受欺凌与青少年时期自杀的高风险相关。女孩,而不是男孩,犯罪者有增加的SI和SA的风险。这些发现强调了针对儿童时期欺凌行为及其长期影响的预防性干预措施的重要性,包括针对男孩和女孩的政策可能存在的差异。
{"title":"Childhood bullying involvement and later suicidality: longitudinal analyses from The Danish National Birth Cohort.","authors":"Lauren Marie Campbell-Hansen, Annette Erlangsen, Keith Hawton, Merete Nordentoft, Trine Madsen","doi":"10.1136/jech-2025-223809","DOIUrl":"10.1136/jech-2025-223809","url":null,"abstract":"<p><strong>Background: </strong>Bullying involvement (victim or perpetrator role) in childhood is linked to later suicidality. However, findings are inconsistent, and sex may be a moderator. We investigated whether childhood bullying involvement was associated with suicidality in adolescence, and whether this association varied by sex.</p><p><strong>Methods: </strong>Childhood bullying involvement was collected from self-reports of children and parents during the 11-year follow-up of the Danish National Birth Cohorts (DNBC). Data on suicidal ideation (SI) and suicide attempts (SA) from the 18-year follow-up were supplemented with hospital records of SA from the National Patient Register. Associations were estimated using multinomial logistic regressions, while inverse probability weighting accounted for socioeconomic-related selection bias.</p><p><strong>Results: </strong>11 705 boys and 17 292 girls were included. Adolescent boys exposed to bullying had increased risks of SI (adjusted relative risk ratio (aRRR): 1.6; 95% CI: 1.4 to 1.8) and SA (aRRR: 2.8; 95% CI: 2.0 to 3.8), while no increased risk was found among those who were perpetrators of bullying vs non-involved peers. Girl victims had increased risks (aRRR) of SI and SA of 1.6 (95% CI: 1.5 to 1.7) and 2.9 (95% CI: 2.5 to 3.5), respectively. Girl perpetrators had an increased risk of SA (aRRR: 2.3; 95% CI: 1.5 to 3.6). Sex significantly moderated the association between perpetration role and suicidality.</p><p><strong>Conclusion: </strong>Childhood bullying was associated with a higher risk of suicidality during adolescence. Girl, but not boy, perpetrators had increased risk of SI and SA. These findings emphasise the importance of preventive interventions targeting bullying in childhood and its long-term effects, including possible differences in policies for boys and girls.</p>","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"47-54"},"PeriodicalIF":3.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyber harassment of physicians as an emerging global health threat: embedding social work in routine care. 对医生的网络骚扰是一种新兴的全球健康威胁:将社会工作纳入日常护理。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-10 DOI: 10.1136/jech-2025-224976
Yan-Ling Lin, Chui-Yu Li
{"title":"Cyber harassment of physicians as an emerging global health threat: embedding social work in routine care.","authors":"Yan-Ling Lin, Chui-Yu Li","doi":"10.1136/jech-2025-224976","DOIUrl":"10.1136/jech-2025-224976","url":null,"abstract":"","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"62"},"PeriodicalIF":3.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invited commentary on: Does the 'right to request' flexible work policy influence men's and women's uptake of flexible working and well-being: findings from the UK Household Longitudinal Study. 特邀评论:“要求灵活工作的权利”政策是否会影响男性和女性对灵活工作和幸福的接受:英国家庭纵向研究的结果。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-10 DOI: 10.1136/jech-2025-224972
Jonathan Platt
{"title":"Invited commentary on: Does the 'right to request' flexible work policy influence men's and women's uptake of flexible working and well-being: findings from the UK Household Longitudinal Study.","authors":"Jonathan Platt","doi":"10.1136/jech-2025-224972","DOIUrl":"10.1136/jech-2025-224972","url":null,"abstract":"","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"25-26"},"PeriodicalIF":3.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Epidemiology and Community Health
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