Jcpsp-Journal of the College of Physicians and Surgeons Pakistan最新文献

Objective: To determine the prevalence of depression, subjective work-related stress and associated factors among men who have sex with men and transgender people working in community-based organisations in Pakistan.

Study design: Cross-sectional descriptive study. Place and Duration of the Study: Community-based organisations in Lahore, October 2022.

Methodology: Community-based organisations were contacted and link of the study tool in the Urdu language was shared. The study tool consisted of sociodemographic questions, substance abuse history, Patient Health Questionnaire (PHQ) 9, the General Self-Efficacy Scale (GSE), and the Subjective job stress scale (SJSS). The composite score for each scale was calculated and compared.

Results: A total of 91 men participated in the study. Of them, 52.1% were below 30 years of age. The mean PHQ-9 score was 7.62 (range 0-27), mean GSE score was 32.38 (range 12-40), and mean SJSS score was 10.48 (4-14). While 41.7% of the participants were not depressed, 31.77% had depression of at least moderate severity. About 56.52% of the study participants had an SJSS score of more than ten showing a high level of work-related stress.

Conclusion: There is a high frequency of depression among MSM and TG community health workers. High degree of self-efficacy may protect against depression. There is a need of developing comprehensive referral systems with psychiatric units for these community workers.

Key words: Community health workers, Homosexual men, Transgender, Depression.

Objective: To evaluate T1 mapping values in different concentrations of iodine and mixed blood and to simulate the application of T1 mapping in differentiating iodine contrast extravasation and haemorrhage transformation after revascularisation in acute ischemic stroke.

Study design: A phantom-based experimental study. Place and Duration of the Study: Department of Radiology, the Second Affiliated Hospital of Soochow University, China, from October 2020 to December 2021.

Methodology: Fresh blood, pure iodine, blood-iodine mixtures (75/25, 50/50, and 25/75 ratios), and diluted iodine (at a concentration of 2.1 mmol I/L) were scanned in a phantom on 3-T MR T1 mapping imaging. A total of 10 layers in the middle section of tubes were scanned. The mean value of T1 mapping and 95% confidence interval for the investigated sample compositions were calculated and compared by ANOVA.

Results: The mean values (95% CI) for fresh blood, [2/3] blood +[1/3] iodine, [1/2] blood +[1/2] iodine, [1/3] blood +[2/3] iodine, and pure iodine were 2108.69 ± 1966.68-2250.71(ms), 1991.72 ± 1763.22-2220.21(ms), 1811.62 ± 1614.79-2008.45(ms), 1624.39 ± 1442.41-1806.37(ms), 1294.68 ± 1172.92-1416.44(ms), respectively. The differences between the T1 mapping values of all compositions were significant (p <0.01), except for fresh blood and the sample consisting of 67% blood. The mean value on T1 mapping (95% CI) was 1294.68 ± 1172.92-1416.44 (ms) in the samples only with diluted iodine, which was significantly different from other investigated samples (p <0.01). The intra-class correlation coefficient between the two times drawing of radiologist A was excellent (ICC=0.913, p<0.01), and between radiologists A and B was 0.99.

Conclusion: Iodine contrast extravasation in a phantom setting might be distinguished from haemorrhagic transformation using T1 mapping.

Key words: Acute ischemic stroke, Haemorrhage transformation, Contrast extravasation, Magnetic resonance imaging, T1 mapping, 3T MRI.

This study aimed to conduct a meta-analysis to assess the possible risk factors of stroke-associated pneumonia (SAP). A comprehensive search of PubMed, Medline, and Cochrane Library was gathered from 2000 to April 2022. A case-control study evaluating the risk factors of SAP was selected. The major finding of this study was that dysphagia, atrial fibrillation, gender, diabetes mellitus, and hypertension were risk factors that determine the development of SAP. The random-effects strategy was used to highlight study-specific outcomes. Only 14 papers out of 651 met the criteria for inclusion and were included in the study. The quality of this study was generally excellent. Risk factors associated with SAP were gender (pooled OR 1.48,95% CI 1.18-1.85), dysphagia (pooled OR 2.61, 95% CI 1.97-3.46), atrial fibrillation (pooled OR 2.08, 95% CI 1.68-2.57), diabetes mellitus (pooled OR 1.32, 95% CI 1.17-1.49), hypertension (pooled OR 1.19, 95% CI 1.05-1.34). This research is crucial because some risk factors are easily recognised, and patients with one or more of these risk factors were developing SAP. Disorders such as dysphagia, atrial fibrillation, diabetes, and hypertension should be addressed and managed to reduce the incidence of SAP conundrums. Key Words: Ischemic stroke, Pneumonia, Risk factor.