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Effectiveness of Two Differently Processed Bovine-Derived Xenografts for Alveolar Ridge Preservation with a Minimally Invasive Tooth Extraction Approach: A Feasibility Clinical Trial. 两种不同处理的牛来源异种移植物用微创拔牙方法保存牙槽嵴的有效性:一项可行性临床试验。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2023-09-01 DOI: 10.11607/prd.6128
Behnam Shakibaie, Markus B Blatz, Hamoun Sabri, Ebrahim Dastouri Jamnani, Shayan Barootchi

Xenogeneic-derived biomaterials are among the most routinely employed bone substitutes for immediate grafting of extraction sites as a modality of alveolar ridge preservation (ARP). The deproteinized bovine bone material is widely used and documented around the world. The present pilot clinical trial evaluated and compared the clinical and morphologic alterations of extraction sites after ARP using two commercially available yet differently processed bovine bone grafts. A total of 20 adjacent extraction sites in 10 patients were included. All sites received the exact same ARP therapy except for the type of bovine bone graft, which was randomly assigned between two adjacent extraction sockets in 10 patients (Group A received Bio-Oss particles and Group B received Cerabone particles). At all sites, healing was monitored at the time of surgery and at 1, 2, 3, and 4 months postoperative. All of the augmented extraction sites achieved successful implant therapy regardless of the bone graft material used for ARP. Six weeks after implant placement, second-stage/uncovering procedures were performed without complications. Intergroup comparisons of the crestal gingival healing process (CGHP), mean transversal crestal ridge resorption (MTRR), and mean implant primary stability (MIPS) were in favor of Group A sites (treatment with Bio-Oss particles).

异种来源的生物材料是最常用的骨替代品之一,可作为牙槽嵴保存(ARP)的一种方式立即移植提取部位。脱蛋白牛骨材料在世界各地被广泛使用和记录。目前的试点临床试验使用两种市售但加工不同的牛骨移植物评估并比较了ARP后提取部位的临床和形态学变化。共包括10名患者的20个相邻提取部位。除了牛骨移植物类型外,所有部位都接受了完全相同的ARP治疗,牛骨移动物类型被随机分配在10名患者的两个相邻提取插座之间(A组接受Bio-Oss颗粒,B组接受Cerabone颗粒)。在所有部位,在手术时以及术后1、2、3和4个月监测愈合情况。无论用于ARP的骨移植物材料如何,所有增强的提取部位都实现了成功的植入治疗。植入后6周,进行了第二阶段/揭盖手术,没有出现并发症。冠牙龈愈合过程(CGHP)、平均横向冠嵴吸收(MTRR)和平均植入物一次稳定性(MIPS)的组间比较有利于A组部位(用Bio-Oss颗粒治疗)。
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引用次数: 0
Periodontal Regeneration with Amnion-Chorion Membrane on Root Surface: A Retrospective Case Series. 根面羊膜牙周再生:一个回顾性病例系列。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2023-09-01 DOI: 10.11607/prd.6105
Lan-Lin Chiou, Munehiko Ro, Yusuke Hamada

This retrospective case series investigated the clinical and radiographic outcomes in 19 intrabony defects treated with periodontal regenerative therapy utilizing a combined approach. Placing an amnion-chorion membrane (ACM) as a biologic modifier on the root surface of the periodontally diseased tooth, combined with bone substitutes and an additional ACM as a barrier membrane, the treated sites were examined 8 to 24 months after the therapy. The preoperative (baseline) mean probing pocket depth (PPD) was 7.21 ± 1.08 mm, and the mean clinical attachment level (CAL) was 7.68 ± 1.49 mm. A mean PPD reduction of 4.05 ± 1.22 mm, CAL gain of 3.68 ± 1.34 mm, and 73.91% ± 22.02% of bone fill were recorded postoperatively. Without any adverse events, root-surface application of ACM as a biologic material in periodontal regenerative therapy could be a safe and cost-effective approach.

本回顾性病例系列研究了采用联合方法进行牙周再生治疗的19例骨内缺损的临床和放射学结果。将羊膜绒毛膜(ACM)作为生物改性剂放置在牙周病牙的根表面,结合骨替代品和额外的ACM作为屏障膜,在治疗后8至24个月检查治疗部位。术前(基线)平均探测袋深度(PPD)为7.21±1.08 mm,平均临床附着水平(CAL)为7.68±1.49 mm。术后记录的PPD平均减少4.05±1.22 mm,CAL增加3.68±1.34 mm,骨填充73.91%±22.02%。在没有任何不良事件的情况下,ACM作为一种生物材料在牙周再生治疗中的根面应用可能是一种安全且具有成本效益的方法。
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引用次数: 0
Treatment of Esthetic Complications with Peri-implant Soft Tissue: A Description of the "Apical Approach" Surgical Technique and Presentation of Two Clinical Cases 种植体周围软组织治疗美学并发症——“根尖入路”手术技术介绍及两例临床病例介绍
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2023-09-01 DOI: 10.11607/prd.6151
Norberto Quispe-López, Javier Flores-Fraile, Ignacio Fernández-Baca, Juan Sánchez-Santos, Jesús Mena-Álvarez, Javier Montero-Martín

Peri-implant soft tissue deformities are an increasingly common phenomenon in the esthetic zone. While the most widely studied esthetic complications are peri-implant soft tissue dehiscences, there are other esthetic concerns in routine clinical practice that require investigation and treatment. Thus, this report on two clinical cases describes a surgical approach using the apical access technique to treat peri-implant soft tissue discoloration and fenestration. In both clinical scenarios, the defect was accessed via a single horizontal apical incision without removing the cement-retained crowns. A bilaminar technique using apical access with a simultaneous connective tissue graft seems to offer promising results for the treatment of peri-implant soft tissue deformities. At the 12-month reevaluation, an increase in peri-implant soft tissue thickness was observed, resolving the pathologies presented.

种植体周围软组织畸形在美容领域越来越普遍。虽然研究最广泛的美学并发症是种植体周围软组织开裂,但在常规临床实践中还有其他美学问题需要调查和治疗。因此,这篇关于两例临床病例的报告描述了一种使用根尖进入技术治疗种植体周围软组织变色和开窗的手术方法。在这两种临床情况下,通过一个水平的根尖切口进入缺损,而不移除水泥保留的牙冠。一种使用根尖接入和同时进行结缔组织移植的双层技术似乎为治疗种植体周围软组织畸形提供了有希望的结果。在12个月的重新评估中,观察到种植体周围软组织厚度增加,从而解决了出现的病理问题。
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引用次数: 0
Buccal Contour Grafting for Periodontally Compromised Teeth with Horizontal Bone Loss: Prospective Cohort Assessment at 1 Year. 颊部轮廓移植治疗牙周受损且水平骨缺失的牙齿:1 年后的前瞻性队列评估。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2023-08-31 DOI: 10.11607/prd.6891
Neel Bhatavadekar, Ninad Padhye

The effects of buccal contour augmentation, for periodontally compromised teeth with horizontal bone loss, was assessed in this study. 30 subjects were divided into group A (open flap debridement [OFD] with buccal contour augmentation using deproteinized bovine bone mineral [DBBM]), jointly referred to as Contour augmentation for Periodontal Defects (CAPD); and group B (OFD alone). Bleeding on probing (BOP), clinical attachment level (CAL), probing depth (PD), gingival recession (GR), width (WKM) and thickness (TKM) of keratinized mucosa and labial cortical plate thickness were compared at baseline and 1-year. BOP, CAL, PD and GR did not show significant differences. TKM increased by 1.76 mm for group A, while decreased by 1 mm for group B. WKM increased from 2.86 ± 0.4 mm to 3.6 ± 0.71 mm (p<0.001) and 2.93 ± 0.32 mm to 3 ± 0.7 mm (p = 0.5) for groups A and B respectively, which showed a statistical significance. Labial cortical plate thickness increased from 0.94 ± 0.3 mm to 1.95 ± 0.54 mm (p<0.001) for group A, while decreased from 0.87 ± 0.45 mm to 0.68 ± 0.31 mm for group B. Visual analog scale score for pain perception showed no difference between the 2 groups. Contour augmentation (CAPD) with DBBM for periodontally compromised teeth improves WKM and TKM. Long-term analyses are needed to determine its benefits in daily clinical practice.

本研究评估了颊部轮廓增量术对水平骨质流失的牙周受损牙齿的效果。30 名受试者被分为 A 组(开放性牙瓣清创术 (OFD),使用去蛋白牛骨矿物质 (DBBM) 进行颊侧轮廓增量术)和 B 组(仅进行开放性牙瓣清创术)。在基线和 1 年时比较探诊出血量 (BOP)、临床附着水平 (CAL)、探诊深度 (PD)、牙龈退缩 (GR)、角化粘膜宽度 (WKM) 和厚度 (TKM) 以及唇皮质板厚度。BOP、CAL、PD 和 GR 均无明显差异。A 组的 TKM 增加了 1.76 毫米,而 B 组则减少了 1 毫米。
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引用次数: 0
Performance and Strength Characteristics of Suture Knots in Periodontal Microsurgery: An In Vitro Study. 牙周显微手术中缝合线结的性能和强度特征:体外研究
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-08-31 DOI: 10.11607/prd.6899
Alina Ariceta, Mirian Elizabeth Casco, Paula Kurlander, Francisca Forti, Antonion Camarano, Roberto Volfovicz, Hsun-Lian Chan, Diego Velásquez-Plata

Background: This study is aimed to investigate the types of knot failure (untying or breaking) and the tension required to break different sutures diameters.

Methods: One hundred and fifty knots were fabricated using polyamide sutures diameters of 6/0, 7/0, and 8/0. The studied knots were either squared or slipped with different numbers of throws (2, 3, 4, 5 and 6), and the following data were recorded: type of failure (untied or broken), number of throws, the tension required to untie or break each knot, slippage, and elongation of the knot. The knots were created in a standardized way. with a device and weights and then subjected to a controlled tension.

Results: The knots that got untied were: 1=1, 1x1, 2=1, and 2x1, whereas the remaining knots got broken. Notably, at least three throws were required to prevent untying, but separately, as in 1=1=1 or 1x1x1. The mean tension to break the knots of 6/0, 7/0, and 8/0 sutures were 3.1, 1.3, and 0.6 N, respectively (P < 0.05), and they were independent of the knot type.

Conclusion: Results from this study demonstrated that the knots with geometries of 2=2/2x2 and 1=1=1/1x1x1 were secure, and additional throws does not increase their security. Furthermore, tensile strength reduces with decreased suture size.

背景:本研究旨在探讨缝合线打结失败的类型(解结或断线)以及不同直径缝合线断线所需的张力:本研究旨在调查绳结失效的类型(松开或断开)以及断开不同直径缝合线所需的张力:使用直径分别为 6/0、7/0 和 8/0 的聚酰胺缝合线制作了 150 个绳结,这些绳结或呈方形,或以不同的打结次数(2、3、4、5 和 6)滑动,并记录了以下数据:失败类型(松开或断开)、打结次数、松开或断开每个绳结所需的张力、滑动以及绳结的伸长率。绳结是以标准化的方式用装置和砝码打出来的,然后受到可控的拉力:解开的绳结有结果:解开的绳结有:1=1、1x1、2=1 和 2x1。值得注意的是,至少需要三次抛掷才能防止绳结松开,但要分别进行,如 1=1=1 或 1x1x1。6/0、7/0 和 8/0 缝合线打结时的平均张力分别为 3.1、1.3 和 0.6 N(P < 0.05),且与线结类型无关:该研究结果表明,几何形状为 2=2/2x2 和 1=1=1/1x1x1 的结是安全的,额外的抛掷并不会增加其安全性。此外,拉伸强度会随着缝合线尺寸的减小而降低。
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引用次数: 0
Correlation of gingival stippling with periodontal phenotypical features: A cross-sectional study. 牙龈条纹与牙周表型特征的相关性:横断面研究
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-08-31 DOI: 10.11607/prd.6879
Emilio Couso-Queiruga, Gustavo Avila-Ortiz, Eliane Porto Barboza, Leandro Chambrone, Huseyn Gencay Keceli, Birtain Tolga Yilmaz, Diogo Moreira Rodrigues

This study aimed at determining the correlation between gingival stippling (GS) and other phenotypical characteristics. Adult subjects in need of cone-beam computed tomography scans (CBCT) and comprehensive dental treatment in the maxillary anterior region were recruited. Facial gingival thickness [GT] and buccal bone thickness [BT] were assessed utilizing CBCT. Standardized intraoral photographs were obtained to determine keratinized tissue width (KTW), presence of GS in all facial and interproximal areas between the maxillary canines, and other variables of interest, such as gingival architecture (GA), tooth shape, and location. Statistical analyses to assess different correlations among recorded variables were conducted. A total of 100 participants and 600 maxillary anterior teeth constituted the study population and sample, respectively. Facial GS was observed in 56% of males and 44% of females, and it was more frequently associated with flat GA, triangular and square/tapered teeth, central incisors, and males. Greater mean values of GT, BT, and KTW were observed in facial areas that exhibited GS. Interdental GS was present in 73% of the sites and it was more frequently observed in males, the central incisor region, and when facial GS was present. Multilevel logistic regression revealed a statistically significant association between the presence of GS and KTW, BT measured at 3mm apical to the bone crest, and tooth type. This information can be used in the recognition of common periodontal phenotypical patterns associated with specific features of great clinical significance.

本研究旨在确定牙龈条纹(GS)与其他表型特征之间的相关性。研究人员招募了需要进行锥形束计算机断层扫描(CBCT)和上颌前牙综合治疗的成年受试者。利用 CBCT 评估面部牙龈厚度 [GT] 和颊骨厚度 [BT]。获得标准化的口内照片,以确定角化组织宽度(KTW)、上颌犬齿之间的所有面部和近端区域是否存在GS,以及其他相关变量,如牙龈结构(GA)、牙齿形状和位置。我们进行了统计分析,以评估记录变量之间的不同相关性。共有 100 名参与者和 600 颗上颌前牙分别构成了研究人群和样本。56%的男性和44%的女性被观察到面部GS,它更多地与扁平GA、三角形和方形/锥形牙齿、中切牙和男性相关。在出现GS的面部区域观察到更大的GT、BT和KTW平均值。73%的部位存在牙间GS,男性、中切牙区域和面部存在牙间GS时更常出现牙间GS。多层次逻辑回归显示,GS的存在与KTW、在骨嵴根尖3毫米处测量的BT以及牙齿类型之间存在统计学意义上的显著关联。这些信息可用于识别与具有重要临床意义的特定特征相关的常见牙周表型模式。
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引用次数: 0
Synchrotron Analysis of Damaged Extraction Sockets Augmented Using a Synthetic Bone Block: A Pilot Study. 使用合成骨块对受损的拔牙套筒进行同步加速器分析:试点研究。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2023-08-08 DOI: 10.11607/prd.6468
Jin-Young Park, Joo-Yeon Lee, Shinyoung Park, Jae-Kook Cha, Jung-Seok Lee, Ui-Won Jung

Aim: To investigate the dimensional stability and quality of the alveolar ridge augmented using a synthetic bone block (SBB) at damaged extraction sockets.

Materials and methods: Four participants were included in whom socket augmentation was performed using SBB and a collagen membrane. Intraoral scan (IOS) was performed before extraction (baseline), immediately postoperative (IP), and at 6 months (6M). Cone-beam computed tomography (CBCT) was performed at IP and 6M. At 6M, a trephine biopsy was obtained during implant placement and the sample was observed using synchrotron. Profilometric change of soft tissue was measured from the IOS data, hard tissue dimensional change was measured from the CBCT data and the bone quality from synchrotron data.

Results: There were minimal changes in the soft tissue profile between baseline and IP, baseline and 6M, and IP and 6M (0.11±1.08 and 0.02±0.8, and -0.65±0.82 mm3). Horizontal bone width measured at 1 mm increments from the augmented bone crest to 5 mm apically revealed only slight reduction (less than 1 mm) at all levels between IP and 6M. The augmented bone height was well maintained from IP until 6M (-0.21±0.53 mm). Synchrotron analysis revealed low to moderate bone quality after 6M (percentage new bone = 16.49±4.91).

Conclusions: Augmentation of the damaged extraction socket using SBB is a viable technique, in which the dimensions of the augmented ridge can be maintained up to 6M. Further long term randomized clinical trial is needed.

目的:研究使用合成骨块(SBB)对受损拔牙窝进行牙槽嵴增量的尺寸稳定性和质量:四名参与者使用合成骨块(SBB)和胶原膜进行了牙槽骨增量术。分别在拔牙前(基线)、术后即刻(IP)和术后 6 个月(6M)进行了口内扫描(IOS)。IP和6个月时进行锥形束计算机断层扫描(CBCT)。在 6 个月时,在植入种植体时进行了取样活检,并使用同步加速器对样本进行了观察。根据 IOS 数据测量软组织的轮廓变化,根据 CBCT 数据测量硬组织的尺寸变化,根据同步加速器数据测量骨质:结果:基线和 IP、基线和 6M、IP 和 6M 之间的软组织轮廓变化极小(0.11±1.08 和 0.02±0.8 以及 -0.65±0.82 mm3)。从增量骨嵴到根尖 5 mm 处以 1 mm 为增量测量的水平骨宽度显示,在 IP 和 6M 之间的所有水平上仅有轻微减少(小于 1 mm)。从 IP 到 6M,增高的骨高度保持良好(-0.21±0.53 mm)。同步加速器分析显示,6M后的骨质量为中低水平(新骨百分比=16.49±4.91):结论:使用SBB对受损的拔牙窝进行扩增是一种可行的技术,扩增脊的尺寸可以保持到6M。需要进一步进行长期随机临床试验。
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引用次数: 0
Management of a Peripheral Giant Cell Granuloma Related to an Implant Supported Prosthesis: A Case Report. 与植入支撑假体相关的外周巨细胞肉芽肿的处理:病例报告。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2023-08-08 DOI: 10.11607/prd.6611
Afroditi Pita, Steve Ruiz

Introduction: Peripheral Giant Cell Granulomas (PGCGs) are benign oral cavity tumors, reactive in nature, caused by local trauma or irritation.

Case presentation: A 51-year-old female patient presented with a soft tissue lesion related to implant site #19. Excisional biopsy was completed, and the soft tissue mass was diagnosed as a Peripheral Giant Cell Granuloma (PGCG). The biopsy led to absence of keratinized tissue and vestibular depth around the implant site. After the initial healing phase of the biopsy, a free gingival graft was completed and following the maturation of the soft tissue the cement retained implant supported prosthesis was converted into a screw retained implant supported prosthesis.

Conclusion: With a combined periodontal and restorative approach increased KT, adequate vestibular depth, no recurrence of the PGCG was achieved as well as an easily accessible screw retained implant supported prosthesis.

导言:周围巨细胞肉芽肿(PGCGs)是一种良性口腔肿瘤,具有反应性,由局部创伤或刺激引起:一名 51 岁的女性患者因与 19 号种植体部位相关的软组织病变就诊。切除活检后,软组织肿块被诊断为周围巨细胞肉芽肿(PGCG)。活检结果显示,植入部位周围没有角化组织和前庭深度。活检后的初期愈合阶段完成了游离龈移植,软组织成熟后,水泥固位的种植体支持修复体转变为螺钉固位的种植体支持修复体:结论:通过牙周和修复相结合的方法,增加了 KT,达到了足够的前庭深度,PGCG 没有复发,而且种植体支持的螺钉固位修复也很容易获得。
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引用次数: 0
Utilizing Individualized Titanium Frames (ITFs) for Protected Alveolar Bone Augmentation: A feasibility case series. 利用个性化钛架(ITF)进行保护性牙槽骨增量术:可行性病例系列。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2023-08-08 DOI: 10.11607/prd.6568
Shih-Cheng Wen, Muhammad Saleh, Abdusalam Alrmali, David T Wu, Hom-Lay Wang

Despite the various barrier membranes proposed, one of the main challenges for guided bone regeneration (GBR) is space maintenance for large defects as well as ensure adequate blood supply. The presented feasibility case series aims to introduce an original titanium frame (TF) design, customized for each defect, as a modification of well-known principles and materials for GBR, for an enhanced and more predictable horizontal and vertical bone augmentation. Three patients with significant horizontal defects were treated with pre-trimmed TFs to create needed space, a 50%-50% mixture of autograft and bovine xenograft was placed, and then covered with collagen membrane. After 8 months of healing, the sites were reopened, the titanium screws were removed with the frame. An average of 8.0 ± 1.0mm horizontal and 3.0 ± 0.0mm vertical bone gain was achieved at the time of re-entry and implant placement surgery. Bone core biopsy was obtained during the implant placement. Histomorphometric analysis revealed that 42.8% of the sample was new vital bone, 18.8% was residual bone graft particles, and 38.4% was bone marrow like structures. After 3-4 months from implant placement, the implants were restored with provisional crowns and then finalized with zirconia screw-retained crowns. This case series suggests that GBR utilizing TFs with or without collagen membranes can be considered a suitable approach for horizontal and vertical bone augmentation. However, based on only three reported cases, the result should be carefully interpreted.

尽管提出了各种屏障膜,但引导骨再生(GBR)的主要挑战之一是维持大缺损的空间以及确保充足的血液供应。本文介绍的可行性病例系列旨在引入一种原创的钛框架(TF)设计,为每个缺损量身定制,作为对 GBR 众所周知的原理和材料的改良,以增强水平和垂直骨增量的可预测性。三位有明显水平缺损的患者接受了预先修剪的 TF 治疗,以创造所需的空间,然后植入 50%-50% 的自体移植和牛异种移植混合物,再用胶原膜覆盖。8 个月愈合后,重新打开手术部位,取出钛螺钉和骨架。重新植入和植入手术时,水平骨增量平均为 8.0 ± 1.0 毫米,垂直骨增量平均为 3.0 ± 0.0 毫米。种植体植入过程中进行了骨核活检。组织形态计量分析显示,42.8%的样本为新的活力骨,18.8%为残留的植骨颗粒,38.4%为类似骨髓的结构。种植体植入 3-4 个月后,使用临时冠修复种植体,最后使用氧化锆螺钉固位冠。该系列病例表明,利用带或不带胶原膜的 TF 进行 GBR 是一种适合水平和垂直骨增量的方法。然而,基于仅有的三例报告,对结果的解释还需谨慎。
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引用次数: 0
Efficacy of Acellular Dermal Matrix Versus Connective Tissue Graft for Root Coverage in Patients with Gingival Recession: A Meta-Analysis. 脱细胞真皮基质与结缔组织移植对牙龈萎缩患者牙根覆盖的疗效:一项荟萃分析。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2023-08-08 DOI: 10.11607/prd.5379
Zhitao Wang, Tianyang Zhai

This study aimed to compare the efficacy of acellular dermal matrix (ADM) versus connective tissue graft (CTG) for root coverage in patients with gingival recession. Randomized controlled trials (RCTs) on the comparison of ADM with CTG in adult patients with gingival recession were searched in multiple databases updated on 15th May 2020. The quality of studies was evaluated using the upgraded Jadad scale. Included studies were assessed for percent root coverage (PRC), clinical attachment level (CAL), keratinized tissue (KT), probing depth (PD), recession width (RW) and recession depth (RD). Weighted mean difference (WMD) was used as the statistics for measurement data and the effect sizes were expressed as 95% confidence intervals (CI). Totally 24 RCTs were eligible for the final analysis. The patients accepting ADM had a higher gain in CAL (WMD: 0.250, 95%CI: 0.030-0.470, P=0.026) but a smaller gain in KT width (WMD: -0.440, 95%CI: -0.629--0.252, P<0.001) than those receiving CTG. No significant differences were found between the patients accepting ADM and those undergoing CTG in PRC (WMD: -1.608, 95%CI: -3.491-0.275, P=0.094), PD (WMD: 0.066, 95%CI: -0.005-0.137, P=0.067), RW (WMD: 0.065, 95%CI: -0.098-0.228, P=0.437) and RD (WMD: 0.109, 95%CI: -0.095-0.314, P=0.294). Overall, the ADM treatment for patients with gingival recession may be superior to CTG in gaining CAL, but CTG has a significant advantage over ADM in gaining KT width.

本研究旨在比较脱细胞真皮基质(ADM)与结缔组织移植物(CTG)对牙龈萎缩患者牙根覆盖的疗效。在2020年5月15日更新的多个数据库中检索了ADM与CTG在成年牙龈退缩患者中比较的随机对照试验(RCTs)。采用升级版Jadad量表评价研究质量。纳入的研究评估了根覆盖百分比(PRC)、临床附着水平(CAL)、角化组织(KT)、探探深度(PD)、退退宽度(RW)和退退深度(RD)。计量资料采用加权平均差(WMD)进行统计,效应量用95%置信区间(CI)表示。共有24项rct符合最终分析的条件。接受ADM的患者CAL增加较高(WMD: 0.250, 95%CI: 0.030 ~ 0.470, P=0.026),但KT宽度增加较小(WMD: -0.440, 95%CI: -0.629 ~ 0.252, P=0.026)
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引用次数: 0
期刊
International Journal of Periodontics & Restorative Dentistry
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