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Group participation and the risk of functional decline in later life: A Prospective Cohort Study. 群体参与与晚年功能衰退的风险:一项前瞻性队列研究。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-07-23 DOI: 10.1177/00469580251348822
Makoto Kaneko, Fumihiro Saitoh, Hotaka Hara, Takako Motomura, Kumiko Maruyama, Yumiko Okamoto, Hisako Kuribayashi, Kouichi Imai, Katsunori Kondo

Although group participation benefits older adults' health, its effects may vary by group type. The Japanese Health and Welfare Co-operative (Hew Co-op) organises peer-led group participation called 'Han Kai' meetings to promote health literacy, but the impact of Han Kai participation on health indicators remains unexplored. This study aimed to examine whether the frequency and duration of Han Kai participation were associated with risk of functional disability. This was a prospective cohort study conducted in Japan between 2018 and 2022. The participants were Han Kai members aged ≥ 65 years who did not receive a Long-Term Care certification. The exposure variables were the frequency of participation in Han Kai per year and the years of participation in 2018. The main outcome was a risk assessment scale score for predicting incident functional disabilities in 2022. Multivariate linear regression was conducted to adjust for covariates. In the study, 2359 older adults participated. Overall, the frequency of Han Kai participation was not significantly associated with disability risk scores. However, participants with ≥10 years of involvement had significantly lower scores (β = -1.95, 95% CI: -3.64 to -0.26, P = .024). Among those aged ≥ 75 years, both frequency and duration showed a significant inverse association with risk scores, with a dose-response relationship. Sustained participation in peer-led group meetings such as Han Kai may help mitigate functional decline, particularly among the oldest age groups. These findings support policies that promote long-term community engagement as part of healthy ageing strategies.

虽然群体参与有益于老年人的健康,但其效果可能因群体类型而异。日本卫生和福利合作社(Hew Co-op)组织了由同行领导的小组参与,称为“韩恺”会议,以促进健康素养,但韩恺参与对健康指标的影响仍未得到探讨。本研究旨在探讨韩恺参与的频率和持续时间是否与功能性残疾的风险相关。这是一项2018年至2022年在日本进行的前瞻性队列研究。参与者为年龄≥65岁且未获得长期护理认证的韩凯会员。暴露变量为每年参与韩恺的频率和2018年的参与年份。主要结果是预测2022年功能性残疾事件的风险评估量表得分。采用多元线性回归对协变量进行校正。在这项研究中,有2359名老年人参与了研究。总体而言,韩恺参与的频率与残疾风险评分没有显著相关。然而,≥10年的参与者得分明显较低(β = -1.95, 95% CI: -3.64至-0.26,P = 0.024)。在年龄≥75岁的患者中,频率和持续时间与风险评分呈显著负相关,呈剂量-反应关系。持续参加像韩恺这样的同龄人领导的小组会议可能有助于缓解功能衰退,尤其是在最年长的群体中。这些发现支持将促进社区长期参与作为健康老龄化战略一部分的政策。
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引用次数: 0
An Empirical Analysis of Anti-Cancer Drug Lags in South Korea. 韩国抗癌药物滞后的实证分析
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-08-11 DOI: 10.1177/00469580251363855
Sung Kyung Lee, Jong Hyuk Lee

This study attempts to examine how cancer drug lags in South Korea, along with submission-to-approval and approval-to-reimbursement decision time spans, have evolved over the last decade, from 2013 to 2022. For the same set of cancer drugs, the drug lags observed in South Korea were compared with those of United States, European Union, and Japan. Multivariate linear regression and multivariate Cox regression analyses were performed to conduct quantitative analyses. Compared with the 3 other advanced medicine agencies, South Korea (Ministry of Food and Drug Safety [MFDS]) displays an average delay of 1 to 2 years in submission and approval over the sample period. However, the average review processing time is much shorter than the submission and approval lags, and the MFDS fares even better than the European Union (European Medicines Agency [EMA]) in terms of reviewing efficiency. Notable progress has been made in addressing delays in the reimbursement decision process, roughly cut in half over the period, whereas other lags are rather elongated. The multivariate regression results confirm that the variations in approval delays in South Korea are largely associated with submission delays. The fact that South Korea fares poorly in submission and ensuing approval lags compared to other nations and regions with advanced medicine agencies mirrors the reality that South Korea is still not yet being considered as one of the most preferred testing grounds for innovative cancer drugs. The findings highlight that the goal of regulators should be geared towards ensuring more equitable access to oncology drugs in a timely manner for the Korean population.

这项研究试图研究韩国癌症药物的滞后性,以及从2013年到2022年,从提交到批准、从批准到报销的决策时间跨度是如何演变的。对于同一组癌症药物,韩国与美国、欧盟和日本的药物滞后进行了比较。采用多元线性回归和多元Cox回归分析进行定量分析。与其他3个先进的医药机构相比,韩国(食品药品安全部[MFDS])在提交和批准样本期间平均延迟1至2年。然而,平均审评处理时间比提交和批准延迟要短得多,而且在审评效率方面,MFDS甚至比欧盟(欧洲药品管理局[EMA])表现得更好。在解决偿还决定过程中的延迟方面取得了显著进展,在此期间大致减少了一半,而其他延迟则相当长。多元回归结果证实,韩国审批延迟的变化在很大程度上与提交延迟有关。与拥有先进医药机构的其他国家和地区相比,韩国在申报和随后的批准方面表现不佳,这反映了一个现实,即韩国仍未被视为最受欢迎的创新癌症药物试验地之一。研究结果强调,监管机构的目标应该是确保韩国人口更公平地及时获得肿瘤药物。
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引用次数: 0
Exploring the Impact of Social Connection Dimensions on Cognitive Impairment in Older Adults: Observational Cohort Study. 探索社会联系维度对老年人认知障碍的影响:观察队列研究。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-08-09 DOI: 10.1177/00469580251356121
Eunjung Lim, Matthew Uechi, Deborah A Taira, James Davis, Kyle M Ishikawa, Joseph Keawe'aimoku Kaholokula

This study aimed to identify unique social connection factors associated with cognitive impairment among older adults. Longitudinal data from the 2010 to 2020 Health and Retirement Study were used. Discrete-time survival models were applied to examine the impact of the social factors like loneliness, depression, positive and negative support from family and friends, volunteerism, attending sports or social clubs, charity work, and computer use on cognitive impairment. The sample included 15 548 adults aged 50 and older, with 11.4% living in poverty. Key factors associated with cognitive impairment were loneliness, depression, charity work, participation in sports or social clubs, computer use, positive family support, and negative family support. In adults living in poverty, depression and computer use were most strongly linked to cognitive impairment. These results underscore the need for interventions and educational programs that help older adults maintain or improve cognitive function through enhanced social connections.

本研究旨在确定与老年人认知障碍相关的独特社会联系因素。研究采用了2010年至2020年健康与退休研究的纵向数据。离散时间生存模型被用于检验社会因素,如孤独、抑郁、来自家人和朋友的积极和消极支持、志愿服务、参加体育或社交俱乐部、慈善工作和电脑使用对认知障碍的影响。样本包括15548名50岁及以上的成年人,其中11.4%生活在贫困中。与认知障碍相关的关键因素是孤独、抑郁、慈善工作、参加体育或社交俱乐部、使用电脑、积极的家庭支持和消极的家庭支持。在生活贫困的成年人中,抑郁和使用电脑与认知障碍的关系最为密切。这些结果强调了干预和教育项目的必要性,这些项目可以通过加强社会联系来帮助老年人维持或改善认知功能。
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引用次数: 0
Endorsement of the Lisbon Outcome Statement and Launch of a National Programme for Age-Friendly Cities and Communities in Portugal. 批准《里斯本成果声明》并启动葡萄牙“关爱老年人城市和社区”国家方案。
IF 1.7 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 DOI: 10.1177/00469580241298829
Miguel Arriaga, Yon Yongjie, Thiago Herick de Sa, Ana Justo, Gisele Câmara, Andreia Costa

Portugal is one of the European Union countries with the highest rates of people aged 65 or more. The old-age dependency index is the third highest in Europe. Longevity is a remarkable human achievement but without a comprehensive approach to fostering healthy ageing over the life-course, the burden on health and care systems and social services will increase. This issue is compounded as life expectancy rises, but many of these additional years are not lived in good health. Promoting healthy ageing is an essential political and moral strategy for the well-being both of individuals and societies. Concerning this, Portugal endorsed the Lisbon Outcome Statement drawn up based on the 2023 Regional Summit on Policy Innovation for Healthy Ageing and made its commitment for the creation of age-friendly environments. The National Programme for Age-Friendly Cities and Communities in Portugal is one of the first concrete steps to fulfill that endorsement.

葡萄牙是欧盟国家中65岁以上老人比例最高的国家之一。老年抚养指数在欧洲排名第三。长寿是一项了不起的人类成就,但如果没有在整个生命过程中促进健康老龄化的综合办法,卫生和保健系统以及社会服务的负担将会增加。随着预期寿命的增加,这一问题变得更加复杂,但其中许多人的健康状况并不好。促进健康老龄化是个人和社会福祉的一项必要的政治和道德战略。为此,葡萄牙批准了根据2023年健康老龄化政策创新区域首脑会议起草的《里斯本成果声明》,并承诺创造对老年人友好的环境。葡萄牙“关爱老年人城市和社区国家方案”是实现这一认可的首批具体步骤之一。
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引用次数: 0
The Association of 340B Program Drug Margins with Covered Entity Characteristics. 340B项目药品边际与覆盖实体特征的关联
IF 1.7 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-03-23 DOI: 10.1177/00469580251324051
Robert J Nordyke, James Motyka, Julie A Patterson

The 340B Drug Pricing Program aims to help facilities serving low-income and uninsured patients to stretch scarce resources by allowing covered entities to purchase outpatient drugs at federally mandated discounted rates while often receiving reimbursement for them at higher rates by commercial payers and Medicare. Despite increasing focus on the expansion and impact of the program, profit margins under 340B have not been fully explored. We aimed to examine drug-, facility-, and geographic-level factors that influence drug margins among 340B covered entities. We conducted a cross-sectional analysis of predictors of facility-level 340B margins for 5 drug classes in a multivariable regression model using 2021 data linked across multiple proprietary and public datasets. Regression results show that drug, facility characteristics, and geographic healthcare market-level characteristics influence drug margins under the 340B program. Adjusted 340B margins were higher in hospital outpatient departments than free-standing offices (ie, hospital-affiliated physician offices and independent, 340B eligible clinics) and among covered entities in more concentrated (ie, less competitive) markets. Covered entity market power, quantified by a facility-level measure of non-340B drug margins indicating pricing power, and area wealth were both associated with higher 340B drug margins. Margins on 340B drugs were higher among facilities in stronger bargaining positions and those serving wealthier areas. These findings add to the growing body of literature on expansions of the 340B program into more affluent communities, informing calls for reforms to ensure the 340B program serves low-income and uninsured patients.

340B药品定价计划旨在帮助服务低收入和未参保患者的机构利用稀缺资源,允许参保机构以联邦规定的折扣价购买门诊药物,同时通常从商业支付者和医疗保险机构获得更高的报销率。尽管人们越来越关注该计划的扩展和影响,但340B下的利润空间尚未得到充分探索。我们的目的是检查药品、设施和地理层面的因素对340B覆盖实体中药品利润的影响。我们在一个多变量回归模型中对5种药物类别的设施级340B利润率的预测因子进行了横断面分析,该模型使用了2021年的数据,这些数据与多个专有和公共数据集相关联。回归结果显示,药品、设施特征和地理医疗保健市场水平特征影响340B计划下的药品利润率。医院门诊部调整后的340B利润率高于独立办公室(即医院附属医生办公室和独立的符合340B条件的诊所)以及在更集中(即竞争较少)市场的承保实体。覆盖实体的市场支配力(通过设施级别的非340B药品利润率衡量,表明定价权)和地区财富都与较高的340B药品利润率相关。在具有较强议价地位的设施和服务于较富裕地区的设施中,340B类药物的利润率较高。这些发现增加了将340B计划扩展到更富裕社区的文献,为改革提供了信息,以确保340B计划服务于低收入和没有保险的患者。
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引用次数: 0
Experiences of Cardiovascular Surgery Intensive Care Nurses in the Care of Patients With Postoperative Cognitive Dysfunction: A Qualitative Study. 心血管外科重症护士对术后认知功能障碍患者的护理经验:一项定性研究。
IF 1.7 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-04-12 DOI: 10.1177/00469580251332061
Hatice Azizoğlu

Postoperative cognitive dysfunction (POCD) is the development of cognitive decline following anesthesia and surgery. The incidence of POCD is more pronounced in patients undergoing cardiac surgery than in patients undergoing non-cardiac surgery. This study aims to evaluate the experiences, knowledge status, and clinical practice interventions of nurses caring for patients diagnosed with POCD. Ten nurses working in the intensive care unit of cardiovascular surgery participated in this study, which used a phenomenological design, one of the qualitative research types. We collected the data face-to-face between January and March 2023 using the individual in-depth interview method. The data were analyzed by the researcher using thematic analysis. The study identified 13 main themes: cognitive, behavioral, emotional problems, occupational difficulties, increasing duration, age, premorbid period, psychological resilience, effective coping skills, interaction, restraint, external support systems, and cognitive structuring. After cardiovascular surgery, patients should be evaluated not only for cardiac but also for cognitive, emotional, and behavioral factors. In addition, the risk factors that cause POCD, the difficulties faced by nurses, and their coping skills are the effects that shape the patient care process of POCD.

术后认知功能障碍(POCD)是麻醉和手术后认知功能下降的发展。心脏手术患者的POCD发生率高于非心脏手术患者。本研究旨在评估护理POCD患者的经验、知识状况及临床实践干预措施。10名心血管外科重症监护病房的护士参与了本研究,本研究采用了质性研究类型之一的现象学设计。我们在2023年1月至3月期间采用个人深度访谈法面对面收集数据。研究者采用主题分析法对数据进行分析。该研究确定了13个主要主题:认知、行为、情感问题、职业困难、持续时间延长、年龄、发病前期、心理弹性、有效应对技能、互动、克制、外部支持系统和认知结构。心血管手术后,患者不仅应评估心脏,还应评估认知、情绪和行为因素。此外,导致POCD的危险因素、护士面临的困难以及他们的应对技能是影响POCD患者护理过程的因素。
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引用次数: 0
Health System Organization and Logistics of Trauma Care Since the Russian Invasion of Ukraine: A Qualitative Assessment. 自俄罗斯入侵乌克兰以来,卫生系统组织和创伤护理后勤:定性评估。
IF 1.7 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-05-07 DOI: 10.1177/00469580251333327
Lynn Lieberman Lawry, Miranda Janvrin, Jessica Korona-Bailey, Christian Betancourt, John Maddox, Kyle Patrick Apilado, Luke Juman, Vivitha Mani, Amandari Kanagaratnam, Zoe Amowitz, Tiffany E Hamm, Oleh Berezyuk, Tracey Pérez Koehlmoos

The February 2022 Russian invasion in Ukraine delayed healthcare reforms. The conflict has led to disruption of medical supply chains and a rapid need for integration between military and civilian entities. This study aims to assess the organization and logistics of the Ukrainian trauma system since the Russian invasion. Qualitative key informant interviews were conducted among Ukrainian military and civilian health care workers using a Ukraine Trauma System Assessment Tool from September 2023 to February 2024. Thematic content analysis was used to derive key themes related to medical logistics and organizational leadership from interviews. Thematic saturation was reached after 36 key informant interviews. Respondents described the roles of the Ministry of Health and Ministry of Defense, as well as the collaboration and integration between military and civilian trauma systems with medical logistics as a key area of focus. Respondents discussed on-going efforts to develop a centralized logistics system to better coordinate supplies and overcome current bureaucratic and communication challenges. The organizational structure and the logistics of the trauma care system in Ukraine are integral to the facilitation of healthcare delivery among both the civilian and military health systems. While rapid coordination has supported triage and increased the efficiency of resources, barriers are still recognized by healthcare personnel including disruptions in the medical supply chain, unpreparedness for large-scale combat operations, inadequate training, outdated equipment, and attacks on infrastructure.

2022年2月俄罗斯入侵乌克兰推迟了医疗改革。冲突导致医疗供应链中断,迫切需要军事和民用实体之间的整合。本研究旨在评估自俄罗斯入侵以来乌克兰创伤系统的组织和后勤。从2023年9月至2024年2月,使用乌克兰创伤系统评估工具对乌克兰军队和民用卫生保健工作者进行了定性关键信息提供者访谈。专题内容分析用于从访谈中得出与医疗后勤和组织领导有关的关键主题。在采访了36个关键信息提供者后,主题饱和度达到了。答复者描述了卫生部和国防部的作用,以及军民创伤系统之间的协作和整合,医疗后勤是一个关键的重点领域。受访者讨论了正在进行的开发集中物流系统的努力,以更好地协调供应并克服当前的官僚主义和沟通挑战。乌克兰创伤护理系统的组织结构和后勤是促进民用和军事卫生系统中医疗保健服务的组成部分。虽然快速协调支持了分诊并提高了资源效率,但卫生保健人员仍然认识到一些障碍,包括医疗供应链中断、大规模作战行动准备不足、培训不足、设备过时以及对基础设施的攻击。
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引用次数: 0
Assessing the Effect of the COVID-19 Pandemic on Community Health Services: A Pre-post Analysis. 评估COVID-19大流行对社区卫生服务的影响:前后分析
IF 1.7 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-05-26 DOI: 10.1177/00469580251338681
Prabhjot Kaur Juttla, Bernard Kimani, Moses Kamita, Teresia Kariuki, Naomi Wachira, Alfred Owino Odongo, Magoma Mwancha-Kwasa

Following COVID-19 containment measures, healthcare service utilization was expected to decline, including in Kenya, across all healthcare tiers. We investigated the impact on community-level health indicators before and during the pandemic. This pre-post study examined community health utilization in 2019 (pre-pandemic) and 2020 (pandemic year) from March to December. Normality was assessed using the Shapiro-Wilk test, followed by Mann-Whitney U or Welch t-tests as appropriate. During the pandemic, facility deliveries (159.2 ± 39.0 vs 496.4 ± 288.2; +237.96%, P = .0232) and ANC referrals (191.0 ± 55.3 vs 630.1 ± 287.2; +229.89%, P = .0008) increased significantly. Child immunization referrals also rose (57.3 ± 11.7 vs 350.2 ± 259.3; +511.17%, P = .0060), while diarrhea treatments in children declined (59.2 ± 47.6 vs 9.2 ± 6.7; -84.46%, P = .0001). Diabetes referrals increased (108.7 ± 65.3 vs 319.5 ± 310.2; +211.15%, P = .035). Households with handwashing facilities saw a non-significant rise (78073.7 ± 16367.9 vs 118457.9 ± 90291.8; +51.73%, P = .3527). Community-level prevention and promotion programs persisted and were enhanced, due to increased fiscal and training support. Even amid crises, community health strategies can adapt and thrive with proper training and funding.

在采取2019冠状病毒病防控措施后,预计包括肯尼亚在内的所有医疗保健级别的医疗保健服务利用率将下降。我们调查了大流行之前和期间对社区一级卫生指标的影响。这项前后研究调查了2019年(大流行前)和2020年(大流行年)(3月至12月)的社区卫生利用情况。使用夏皮罗-威尔克检验评估正态性,然后酌情使用Mann-Whitney U或Welch t检验。大流行期间,设施交付量(159.2±39.0 vs 496.4±288.2;+237.96%, P = 0.0232)和ANC转诊(191.0±55.3 vs 630.1±287.2;+229.89%, P = 0.0008)显著增高。儿童免疫转诊也上升(57.3±11.7 vs 350.2±259.3;+511.17%, P = 0.0060),而儿童腹泻治疗下降(59.2±47.6 vs 9.2±6.7;-84.46%, p = 0.0001)。糖尿病转诊增加(108.7±65.3 vs 319.5±310.2);+211.15%, p = 0.035)。有洗手设施的住户数目无显著上升(78073.7±16367.9 vs 118457.9±90291.8);+51.73%, p = .3527)。由于财政和培训支持的增加,社区一级的预防和促进项目得以持续并得到加强。即使在危机期间,社区卫生战略也可以在适当的培训和资金支持下适应并蓬勃发展。
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引用次数: 0
Closing the Gap: Addressing Racial Bias in Bystander CPR Administration. 缩小差距:解决旁观者心肺复苏管理中的种族偏见。
IF 1.7 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-06-12 DOI: 10.1177/00469580251347867
Ketan Tamirisa, Ethan Lowder, Adriana Mares, Jonathan Jose, Jim P Stimpson

Bystander cardiopulmonary resuscitation (BCPR) significantly improves survival rates for out-of-hospital cardiac arrest (OHCA), yet racial disparities persist. Black and Hispanic individuals are markedly less likely to receive BCPR than White individuals, contributing to preventable deaths and inequities in survival outcomes. Structural factors such as educational barriers, implicit bias, and systemic racism contribute to these disparities. This article examines key contributors to racial disparities in BCPR administration and presents targeted, evidence-based solutions. Educational barriers, including limited CPR training access in historically marginalized communities, low health literacy, and language differences, impede knowledge acquisition and response readiness. Implicit bias among bystanders and first responders influences CPR administration, reinforcing disparities. To address these issues, a multifaceted approach is needed, emphasizing community engagement, culturally responsive training, bias awareness for emergency responders, and policy reforms. Strategies include subsidizing CPR training in underserved communities, developing multilingual and culturally tailored educational materials, integrating CPR instruction into school curricula, and incorporating bias awareness training into first responder certification programs. Additionally, policy interventions should ensure equitable resource allocation to support CPR training and emergency response infrastructure in high-risk communities. Reducing racial disparities in BCPR requires coordinated efforts from policymakers, public health officials, and community stakeholders. Implementing targeted interventions can improve CPR accessibility, enhance response equity, and ultimately reduce preventable mortality among historically disadvantaged populations.

旁观者心肺复苏(BCPR)显著提高院外心脏骤停(OHCA)的存活率,但种族差异仍然存在。黑人和西班牙裔患者接受BCPR的可能性明显低于白人,这导致了可预防的死亡和生存结果的不公平。教育障碍、隐性偏见和系统性种族主义等结构性因素导致了这些差异。本文研究了BCPR管理中种族差异的主要原因,并提出了有针对性的、基于证据的解决方案。教育障碍,包括在历史上被边缘化的社区获得有限的心肺复苏术培训、低卫生素养和语言差异,阻碍了知识获取和应对准备。旁观者和急救人员的内隐偏见影响心肺复苏术的实施,加剧了差异。为解决这些问题,需要采取多方面的办法,强调社区参与、符合文化要求的培训、提高应急人员对偏见的认识以及政策改革。策略包括在服务不足的社区资助心肺复苏培训,开发多语言和适合文化的教育材料,将心肺复苏教学纳入学校课程,并将偏见意识培训纳入急救人员认证计划。此外,政策干预应确保公平分配资源,以支持高危社区的心肺复苏培训和应急基础设施。减少BCPR中的种族差异需要决策者、公共卫生官员和社区利益相关者的协调努力。实施有针对性的干预措施可以改善心肺复苏的可及性,增强应对公平性,并最终降低历史上弱势人群的可预防死亡率。
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引用次数: 0
Development of a Digital Intervention Incorporating Habit Formation Techniques for Medication Adherence. 结合药物依从性习惯形成技术的数字干预的发展。
IF 1.7 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-01 Epub Date: 2025-06-21 DOI: 10.1177/00469580251343785
Sun Kyung Kim, Hye Ri Hwang, Kyung Seok Byun, Su Yeon Park, Su Hee Moon, Huiseok Lee

Effective medication management is essential for preventing complications and improving quality of life in individuals with chronic diseases. A comprehensive approach is required to support patients in improving their medication adherence. This study aimed to develop and validate personalized interventions, using technological tools, designed to support medication habit formation in patients with diabetes. The development process was guided by the Medical Research Council's framework, which includes phases of development, intervention design, feasibility testing, and recommendations for future research. Twenty-five experts in healthcare and psychology were invited and participated in the evaluation. To illustrate the intervention, a 5-min video was produced, showcasing a patient's experience through screen captures of individual components. The evaluation encompassed content validation, usability and usefulness assessments, and qualitative feedback. Expert evaluation identified key challenges and effective features relevant to digital interventions in diabetes care. The intervention, MediHabit, was designed based on digital behavior change principles and habit formation theories. It begins with personalized sessions aimed at establishing a consistent medication-taking routine. Direct and indirect cues are subsequently delivered via a mobile app and a smart medication dispenser, synchronized to ensure accurate and timely medication administration. Patients can self-monitor their adherence and receive motivational messages as rewards. Expert validation emphasized the strengths of customizability and individualization, affirming the content's relevance and the app's usability. However, experts also noted the need for improved accessibility across age groups and more meaningful use of patient-generated data. The findings indicate that the MediHabit intervention holds promising potential for improving medication adherence among diabetic patients. Further research is needed to evaluate its real-world effectiveness, long-term impact, and scalability across diverse populations.

有效的药物管理对于预防并发症和改善慢性疾病患者的生活质量至关重要。需要一个全面的方法来支持患者改善他们的药物依从性。本研究旨在开发和验证个性化干预措施,使用技术工具,旨在支持糖尿病患者的用药习惯形成。开发过程以医学研究理事会的框架为指导,其中包括开发阶段、干预措施设计、可行性测试和对未来研究的建议。25名保健和心理学专家应邀参加了评价。为了说明干预措施,制作了一段5分钟的视频,通过屏幕截图展示了患者的体验。评估包括内容验证、可用性和有用性评估,以及定性反馈。专家评估确定了与糖尿病护理数字干预相关的主要挑战和有效特征。这项名为MediHabit的干预措施是基于数字行为改变原则和习惯形成理论设计的。它从个性化的疗程开始,旨在建立一个一致的药物服用程序。直接和间接的线索随后通过移动应用程序和智能药物分配器传递,同步以确保准确和及时的药物管理。患者可以自我监控自己的依从性,并获得激励信息作为奖励。专家验证强调了可定制性和个性化的优势,肯定了内容的相关性和应用程序的可用性。然而,专家们也指出,需要改善跨年龄组的可及性,并更有意义地使用患者生成的数据。研究结果表明,MediHabit干预在改善糖尿病患者的药物依从性方面具有很大的潜力。需要进一步的研究来评估其在现实世界中的有效性、长期影响以及在不同人群中的可扩展性。
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Inquiry-The Journal of Health Care Organization Provision and Financing
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