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Patient Safety Indicator Sets: Prioritization, Decision-Making Considering Healthcare Resilience, and Implementation Success. 患者安全指标集:优先排序、考虑医疗弹性的决策和实施成功。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-02-18 DOI: 10.1177/00469580261417598
Silke Kuske, Andreas Beckmann, Janina Kitzka, Christine Aumann, Stefanie Deckert, Kathleen Leps, Markus Rinck, Michel Schmidt, Lisa-Marie Rudek, Giorgi Jokhadze, Jochen Schmitt, Ruth Hecker, Max Geraedts

Patient safety indicators are core measures for improving healthcare. We aimed to conceptualize the prioritization of such indicators and the requirements for developing a core set of nationwide, valid, low-bureaucracy patient safety indicators. We also aimed to develop a decision aid for adapting the core set to strengthen the resilience of healthcare provision with respect to crisis situations and to identify factors related to successful implementation. A hybrid focus group design of 4 guided online focus group interviews was used by combining a semi-structured discussion and supporting materials, including questionnaires. The data were analyzed using content and descriptive analysis. A framework for prioritizing patient safety indicators for core set development and adaptation was developed. Indicator prioritization is guided by the aim of the core set, considering stakeholders' needs, potential for improvement, context of use, scientific quality, and implementability criteria. Together with the requirement criteria, such as patient safety dimensions, the breadth and depth of the indicator set can be defined. The developed decision aid for crisis events was deemed suitable for maintaining patient safety. A modular system is recommended for the adaptation of the core set to address several different indicator measurement scenarios. The developed framework and decision aid allow context-(in)dependent prioritization on the basis of the criteria for prioritizing patient safety indicators for a core indicator set and for indicator decision-making in adapting the core set for crisis events. Further real-world validation of the framework and decision aid and the associated criteria is recommended.

患者安全指标是改善医疗保健的核心措施。我们的目标是概念化这些指标的优先次序,以及制定一套全国性、有效、低官僚主义的核心患者安全指标的要求。我们还旨在制定一项决策援助,以调整核心集,以加强医疗保健服务在危机情况下的复原力,并确定与成功实施有关的因素。通过结合半结构化讨论和问卷等辅助材料,采用4个引导在线焦点小组访谈的混合焦点小组设计。采用内容分析和描述性分析对数据进行分析。制定了核心集开发和适应的患者安全指标优先排序框架。指标优先排序以核心集的目标为指导,考虑利益相关者的需求、改进潜力、使用背景、科学质量和可实施性标准。与需求标准(如患者安全尺寸)一起,可以定义指标集的广度和深度。已开发的危机事件决策援助被认为适合于维护患者安全。建议采用模块化系统对核心集进行调整,以解决几种不同的指标测量方案。已开发的框架和决策援助允许根据患者安全指标的核心指标集优先排序标准,以及根据危机事件调整核心指标集的指标决策标准,根据具体情况进行优先排序。建议对框架和决策辅助以及相关标准进行进一步的实际验证。
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引用次数: 0
Active Heat Acclimation Training Offered Better Results in Thermal Rooms in Basic-Training Troops: A Prospective Controlled Study. 基训部队热室主动热适应训练效果较好:一项前瞻性对照研究
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-03-10 DOI: 10.1177/00469580261427681
Lei Liu, Ya-Lin Kong, Li-Hao Xue, Dong-Qing Wen, Zhao Gu, Xiang-Yang Zhang, Ning Li, Bo Ning

Heat acclimation is a critical strategy for preventing heatstroke in military personnel, but traditional heat acclimatization relies on natural environments, unfeasible for military training. This study aimed to establish mobile cabin-type thermal rooms in basic-training troops and evaluate the effects of active and passive heat acclimation training in new soldiers. Mobile cabin-type thermal rooms were constructed in basic-training troops. New soldiers underwent heat tolerance tests, and those identified with poor heat tolerance were randomized into active or passive training groups. Following heat acclimation training, participants were re-evaluated, and physiological responses were compared between groups. A total of 1326 male new soldiers participated in the heat tolerance test; 134 (10.1%) were identified with poor heat tolerance. Among them, 70 were assigned to the active training group and 64 to the passive group. All participants completed training and subsequently passed the heat tolerance test. Both groups showed significant improvements in core physiological and stress indices (P < .05), with no statistical differences between groups (P > .05). However, the rise in core temperature and heart rate occurred faster in the passive group, while a higher proportion of soldiers reported comfort in the active group (P < .05). Mobile cabin-type thermal rooms provide a reliable, rapid method for screening and training heat tolerance in basic-training troops. Both active and passive heat acclimation improved heat tolerance, but active training offered better subjective comfort. This approach enables safe and effective preparation for military personnel in hot environments.

热适应是军事人员预防中暑的重要策略,但传统的热适应依赖于自然环境,不适合军事训练。本研究的目的是在基训部队中建立移动式舱室式热适应室,对新兵进行主动热适应训练和被动热适应训练的效果进行评价。在基训部队建设了移动式舱室式热室。新兵接受了耐热性测试,耐热性差的士兵被随机分为主动训练组和被动训练组。在热适应训练后,对参与者进行重新评估,并比较各组之间的生理反应。共有1326名男新兵参加了耐热性测试;134株(10.1%)耐热性较差。其中,主动训练组70人,被动训练组64人。所有参与者都完成了训练,并随后通过了耐热性测试。两组患者核心生理和应激指标均有显著改善(P < 0.05)。然而,被动组的核心温度和心率上升得更快,而主动组的士兵报告舒适的比例更高(P
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引用次数: 0
Medicare Advantage Enrollment and Total Medicare Program Spending. 医疗保险优势登记和医疗保险计划总支出。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-03-23 DOI: 10.1177/00469580261433163
Brett Alfrey, Aliza S Gordon, Michelle Nguyen Locke, Jennifer L Kowalski

Medicare Advantage (MA) enrollment has grown significantly over the last 2 decades while Medicare program spending per capita has moderated over that same period. An open question is how the growth in MA enrollment has impacted Medicare program spending. The objective of this study is to estimate the association between MA penetration (ie, the percentage of Medicare beneficiaries enrolled in MA) and total Medicare spending per capita. We estimated linear regression models that examine the relationship between county-level MA penetration and total Medicare spending per capita. The study used county-level Medicare spending and enrollment data-including MA, Medicare Fee-for-Service, and Part D-from the Centers for Medicare & Medicaid Services from 2012 to 2021. The study included counties from all 50 states and Washington, D.C. 3045 counties were included in the analysis, which represents 97% of U.S. counties. We found that counties with higher MA penetration showed lower standardized Medicare spending per capita. Specifically, 10 percentage point higher annual MA penetration was associated with $194 lower (P < .001) total Medicare spending per capita, representing 1.5% lower spending. After adjusting risk scores to reflect the Medicare Payment Advisory Commission's estimates of higher coding intensity in MA, 10 percentage point higher annual MA penetration was associated with $146 lower (P < .001) total Medicare spending per capita, representing 1.1% lower spending. If these associations are causal in nature, then higher MA enrollment over the last 2 decades may have moderated total Medicare program spending over the same period.

在过去的20年里,医疗保险优势(MA)的注册人数显著增长,而同期医疗保险计划的人均支出却有所放缓。一个悬而未决的问题是,硕士入学人数的增长如何影响医疗保险计划的支出。本研究的目的是估计医疗保险渗透率(即医疗保险受益人参加医疗保险的百分比)与人均医疗保险总支出之间的关系。我们估计了检验县级MA渗透率与人均医疗保险总支出之间关系的线性回归模型。该研究使用了2012年至2021年医疗保险和医疗补助服务中心的县级医疗保险支出和登记数据,包括MA、医疗保险服务收费和d部分。这项研究包括了所有50个州和华盛顿特区的县,共有3045个县被纳入分析,占美国县的97%。我们发现,MA渗透率较高的县人均标准化医疗保险支出较低。具体来说,年平均销售收入(MA)渗透率提高10个百分点,平均收入(P)就会降低194美元
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引用次数: 0
Sponsor's Perspective: Building a Roadmap of Comprehensive Community Violence Intervention Evaluation Practices. 赞助商的观点:建立一个全面的社区暴力干预评估实践路线图。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1177/00469580251411448
Megan J O'Toole
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引用次数: 0
Self-efficacy and Communication in Health Personnel After Simulation Training in Cardiopulmonary Resuscitation: A Quasi-experimental Study. 心肺复苏模拟训练后医护人员自我效能感与沟通:一项准实验研究。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-02-13 DOI: 10.1177/00469580251411471
María Del Carmen Pérez-Fuentes, María Del Mar Molero Jurado, Armando Romanos-Rodríguez, África Martos Martínez, Francisco J Gómez-Gómez, Javier Aguado-Campos

This study aimed to evaluate the impact of a simulation-based Advanced Life Support (ALS) training programme on the self-efficacy and communication of health personnel. The research focussed on whether such training could enhance both technical and non-technical skills, particularly in managing cardiopulmonary resuscitation (CPR) situations. A quasi-experimental pre- and post-intervention study was conducted in primary care centres across Andalusia, Spain. A total of 106 health personnel (doctors and nurses), aged 21 to 65 years, participated in the study. Participants completed questionnaires measuring self-efficacy and communication styles before and after a 27-hour blended ALS training programme, which incorporated high-fidelity simulation exercises. Communication was assessed across several dimensions, including expressiveness, preciseness, impression manipulativeness, and emotionality. Post-intervention analysis revealed significant changes in communication styles. Specifically, doctors exhibited a reduction in "impression manipulativeness," while nurses showed an increase in "expressiveness." Although self-efficacy scores improved slightly after the training, the changes were not statistically significant. Correlational analyses indicated that higher self-efficacy was positively associated with "expressiveness" and "preciseness," and negatively associated with "emotionality." In conclusion, simulation-based ALS training led to improved communication among health personnel, with distinct patterns emerging between doctors and nurses. While the simulation training did not significantly increase self-efficacy, the trends observed suggest potential benefits. These findings support the inclusion of simulation in continuing professional development programmes to strengthen non-technical skills essential for effective CPR performance.

本研究旨在评估基于模拟的高级生命支持(ALS)培训计划对卫生人员自我效能感和沟通的影响。这项研究的重点是这种培训是否可以提高技术和非技术技能,特别是在处理心肺复苏(CPR)情况方面。在西班牙安达卢西亚的初级保健中心进行了一项准实验的干预前和干预后研究。共有106名年龄在21岁至65岁之间的卫生人员(医生和护士)参加了这项研究。参与者在27小时的ALS混合训练计划前后完成了自我效能感和沟通方式的问卷调查,该计划包括高保真模拟练习。沟通是通过几个维度来评估的,包括表现力、精确性、印象操纵性和情绪性。干预后分析显示,沟通方式发生了显著变化。具体来说,医生表现出“印象操控性”的减少,而护士表现出“表现力”的增加。虽然训练后自我效能得分略有提高,但变化无统计学意义。相关分析表明,较高的自我效能感与“表达性”和“严谨性”呈正相关,与“情绪性”负相关。综上所述,基于模拟的ALS培训改善了医护人员之间的沟通,医生和护士之间出现了不同的模式。虽然模拟训练并没有显著提高自我效能感,但观察到的趋势表明了潜在的好处。这些发现支持将模拟纳入持续的专业发展计划,以加强有效CPR执行所必需的非技术技能。
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引用次数: 0
Balance and Postural Outcomes of Vibration Therapies in Parkinson's Disease: Protocol for a Systematic Review and Meta-Analysis. 振动治疗帕金森病的平衡和体位结果:系统回顾和荟萃分析的方案。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-03-24 DOI: 10.1177/00469580261433160
Ji-Woo Seok, Jung-Dae Kim, Jaeuk U Kim, Se-Ra Park

Balance impairment is a major motor symptom of Parkinson's disease (PD), leading to falls, reduced mobility, and lower quality of life. Despite advances in pharmacological and rehabilitation approaches, postural instability often persists, requiring effective adjunctive interventions. Vibration therapy (VT) is a non-invasive, drug-free method that may enhance neuromuscular and balance control. However, evidence remains inconsistent due to methodological heterogeneity and small samples. This protocol describes a systematic review and meta-analysis designed to evaluate the effects of VT on balance in individuals with PD. Following PRISMA-P 2015 and Cochrane Handbook guidelines, the protocol is registered in PROSPERO (CRD420251124173). Searches will include PubMed, EMBASE, MEDLINE, Web of Science, and Cochrane Library for English-language, peer-reviewed randomized and non-randomized controlled studies comparing VT (WBV, FMV, or SRT) with control interventions. Risk of bias will be assessed using RoB 2 and ROBINS-I tools. A 3-level random-effects meta-analysis will address within-study dependencies, followed by subgroup and meta-regression analyses. Certainty of evidence will be rated using GRADEpro. This review will synthesize available evidence on the effects of vibration therapy on balance and postural outcomes in individuals with Parkinson's disease. Pooled effect sizes will be estimated, and potential sources of heterogeneity will be examined through predefined subgroup analyses and multilevel meta-regression based on clinical and intervention-related factors. This review will clarify the therapeutic potential of VT for balance in PD and guide evidence-based rehabilitation strategies.Systematic review registration: PROSPERO CRD420251124173.

平衡障碍是帕金森病(PD)的主要运动症状,可导致跌倒、活动能力降低和生活质量下降。尽管在药理学和康复方法方面取得了进展,但姿势不稳定经常持续存在,需要有效的辅助干预。振动疗法(VT)是一种非侵入性、无药物的方法,可以增强神经肌肉和平衡控制。然而,由于方法的异质性和小样本,证据仍然不一致。本方案描述了一项系统综述和荟萃分析,旨在评估VT对PD患者平衡的影响。根据PRISMA-P 2015和Cochrane手册指南,该方案已在PROSPERO注册(CRD420251124173)。检索将包括PubMed、EMBASE、MEDLINE、Web of Science和Cochrane Library,检索英文、同行评议的随机和非随机对照研究,比较VT (WBV、FMV或SRT)与对照干预措施。将使用rob2和ROBINS-I工具评估偏倚风险。一个3水平随机效应荟萃分析将解决研究内的依赖关系,然后是亚组和荟萃回归分析。证据的确定性将使用GRADEpro进行评级。本综述将综合现有证据,研究振动疗法对帕金森病患者平衡和体位预后的影响。汇总效应量将被估计,潜在的异质性来源将通过预先定义的亚组分析和基于临床和干预相关因素的多水平meta回归来检验。本综述将阐明VT对PD患者平衡的治疗潜力,并指导循证康复策略。系统评价注册号:PROSPERO CRD420251124173。
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引用次数: 0
Sexual and Reproductive Health Service Utilization and Associated Factors Among Young People With Disabilities in Ethiopia: Systematic Review and Meta-analysis. 埃塞俄比亚残疾青年的性与生殖健康服务利用及其相关因素:系统回顾和荟萃分析
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-02-28 DOI: 10.1177/00469580261420715
Mihiret Tesfaw, Takele Tadesse, Kassa Daka, Amene Abebe

Disability is a major public health concern affecting about 16% of the global population. It results from the interaction of health condition and/or impairments with various contextual personal and environmental factors. All people need access to sexual and reproductive health (SRH) services, but young people with disabilities (YPWDs) need it even more. In Ethiopia, evidence indicates that YPWDs experience substantially limited access to SRH services. This study aimed to systematically identify, appraise, and summarize existing evidence on SRH service utilization and associated factors among YPWDs in Ethiopia. Eight electronic databases were searched for studies published between 2010 and 2024. Microsoft Excel and STATA software were used for data extraction and analysis, respectively. A random-effect model of meta-analysis was conducted. Heterogeneity was assessed using Cochrane's Q and I2 statistics and a funnel plot was used to identify whether there is a publication bias among included studies. Findings are reported according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines. Out of 2105 studies, 9 studies with 4066 YPWDs were included. The pooled prevalence of SRH service utilization among YPWDs in Ethiopia is 36.56% [95% CI: 29.58, 43.55], with P-value < .001 and I2 = 95.76%. Good knowledge of SRH services was significantly associated with service uptake (OR 4.84, [1.16, 20.24], with P-value < .001 and I2 = 87.3%). This study shows that SRH service utilization among YPWDs in Ethiopia remains low, with only 36.56% accessing the service. The significant association between knowledge of SRH and service uptake underscore the need for inclusive SRH strategies tailored to young people with disabilities through adapted communication and service delivery approaches.

残疾是一个重大的公共卫生问题,影响到全球约16%的人口。它是健康状况和/或缺陷与各种背景个人和环境因素相互作用的结果。所有人都需要获得性健康和生殖健康(SRH)服务,但残疾青年(YPWDs)更需要这种服务。在埃塞俄比亚,有证据表明,未成年妇女获得性健康和生殖健康服务的机会非常有限。本研究旨在系统地识别、评估和总结埃塞俄比亚YPWDs中SRH服务利用及其相关因素的现有证据。研究人员检索了2010年至2024年间发表的8个电子数据库。使用Microsoft Excel和STATA软件分别进行数据提取和分析。采用随机效应模型进行meta分析。采用Cochrane's Q和I2统计量评估异质性,并采用漏斗图确定纳入的研究是否存在发表偏倚。根据系统评价和荟萃分析(PRISMA)指南的首选报告项目报告研究结果。在2105项研究中,纳入了9项涉及4066例ypwd的研究。埃塞俄比亚ypwd患者的SRH服务使用率为36.56% [95% CI: 29.58, 43.55], p值I2 = 95.76%。良好的SRH服务知识与服务吸收显著相关(OR 4.84, [1.16, 20.24], p值I2 = 87.3%)。该研究表明,埃塞俄比亚ypd的SRH服务利用率仍然很低,只有36.56%的人获得了该服务。性健康和生殖健康知识与服务接受之间的重要联系强调了通过适应的沟通和服务提供方法为残疾青年量身定制包容性性健康和生殖健康战略的必要性。
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引用次数: 0
Identifying Measurement Dimensions of Users' Benefit-Risk Perceptions of AI in Healthcare: A Scoping Review. 确定医疗保健中人工智能的用户利益-风险感知的测量维度:范围审查。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-03-03 DOI: 10.1177/00469580261427409
Haoning Shi, Yue Xiang, Xilin Yang, Qinghua Zhao, Huanhuan Huang

The rapid integration of artificial intelligence (AI) into healthcare presents a double-edged nature, making systematic assessment of users' benefit-risk perceptions critical. However, a unified, multidimensional framework for such measurement is currently lacking. This review aims to systematically identify and synthesize existing measurement instruments for users' benefit-risk perceptions of AI in healthcare, and to propose an integrated framework based on the evidence. Guided by Arksey and O'Malley's 5-stage framework, we retrieved quantitative studies describing measurement dimensions for users' benefit-risk perceptions regarding AI in healthcare. The search covered 8 Chinese and English databases from their inception to December 6, 2025. Two reviewers independently performed study screening and data extraction, with subsequent synthesis and visual presentation of findings. Based on a synthesis of 49 eligible studies, we developed a measurement framework encompassing 5 benefit and 6 risk dimensions, where technological attributes often exhibit a dual nature. Current measurement instruments consistently emphasize functional benefits, cost benefits, and privacy risks across diverse healthcare contexts, user groups, and geographical regions. In contrast, social benefits and capability development risks generally receive less consideration. Furthermore, variations in instrument design are primarily reflected at the subdimension level. This framework extends classical technology acceptance theories. It provides a theoretical basis for standardized instrument development and offers guidance for the clinical implementation of AI in healthcare. Future research should explore how perceptions evolve with advancing AI maturity and clinical integration to support responsible adoption.

人工智能(AI)与医疗保健的快速整合呈现出双刃剑性质,使得系统评估用户的利益-风险感知至关重要。然而,目前缺乏用于这种度量的统一的多维框架。本综述旨在系统地识别和综合现有的用户对医疗保健中人工智能的利益-风险感知的测量工具,并根据证据提出一个综合框架。在Arksey和O' malley的5阶段框架的指导下,我们检索了描述用户在医疗保健中对人工智能的利益-风险感知的测量维度的定量研究。此次检索涵盖了8个中、英文数据库,检索时间从建立到2025年12月6日。两名审稿人独立进行了研究筛选和数据提取,随后进行了综合和视觉展示。基于49项合格研究的综合,我们开发了一个包含5个利益和6个风险维度的测量框架,其中技术属性通常表现出双重性质。当前的测量工具在不同的医疗环境、用户群体和地理区域中始终强调功能效益、成本效益和隐私风险。相比之下,社会效益和能力发展风险通常较少得到考虑。此外,仪器设计的变化主要反映在子维度水平上。这个框架扩展了经典的技术接受理论。为标准化仪器开发提供理论依据,为人工智能在医疗卫生领域的临床应用提供指导。未来的研究应该探索随着人工智能成熟度的提高和临床整合的发展,人们的看法是如何演变的,以支持负责任的采用。
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引用次数: 0
Prevalence of Labor Induction, its Indication, and Feto-Maternal Outcomes in Ethiopia: A Systematic Review and Meta-Analysis. 引产的流行,它的指征,和胎母结局在埃塞俄比亚:一个系统的回顾和荟萃分析。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-01-08 DOI: 10.1177/00469580251411644
Zerihun Figa, Addisu Getnet Zemeskel, Asrat Alemu, Anteneh Gashaw, Aschalew Gossaye Ejigu, Nigatu Tilahun, Tesfaye Temesgen, Fikru Bedecha, Bereket Tesfaye Gebre

Labor induction (IOL) is a common obstetric intervention to stimulate uterine contractions before the spontaneous onset of labor, with the goal of achieving vaginal delivery. It is indicated for various reasons, including post-term pregnancy, premature rupture of membranes (PROM), maternal medical conditions, and fetal growth restriction. This study aims to evaluate the prevalence of labor induction, its indications, and the associated maternal and fetal outcomes in Ethiopia. A comprehensive search for relevant articles was conducted using widely recognized databases such as Google Scholar, Cochrane, PubMed, HINARI, Web of Science, African Online, and institutional repositories from Ethiopian universities. Data were extracted using the standard format provided by the Joanna Briggs Institute. The Cochran Q test and I2 statistics were employed to assess the heterogeneity of the studies. Publication bias was evaluated using a Funnel plot and Egger's test. A Forest plot was used to present the pooled prevalence of labor induction in Ethiopia. This systematic review and meta-analysis revealed that the overall pooled prevalence of induction of labor in Ethiopia was 14.4% (95% CI: 11.09-17.70; I2 = 95.7%, P < .01). The primary indications for labor induction included premature rupture of membranes (33.91%), intrauterine fetal death (8.8%), intrauterine growth restriction (4.85%), post-term pregnancy (21.49%), oligohydramnios (12.2%), and hypertensive disorders (30.7%). Maternal complications related to induction of labor included postpartum hemorrhage (9.47%), cesarean section (28.68%), instrumental delivery (18.82%), and vaginal tears (14.45%). Adverse fetal outcomes included low Apgar scores at 1 min, fetal death, and neonatal intensive care unit (NICU) admission, with respective rates of 48.2%, 6.11%, and 15.5%. According to this systematic review and meta-analysis, the estimated overall prevalence of induction of labor in Ethiopia is 14.4%. The indications for induction of labor include premature rupture of membranes (PROM), intrauterine fetal death (IUFD), intrauterine growth restriction (IUGR), post-term pregnancy, oligohydramnios, and hypertensive disorders. Maternal complications of labor induction include postpartum hemorrhage (PPH), cesarean section, instrumental delivery, and vaginal tear. Adverse fetal outcomes associated with induction of labor include a low first-minute Apgar score, fetal death, and admission to the neonatal intensive care unit (NICU). Careful consideration and balancing of risks are essential when deciding to induce labor. Additionally, clear national protocols and follow-up on induction of labor are crucial to mitigate these risks. Registration number: reviewregistry2051.

人工引产(IOL)是一种常见的产科干预措施,在自然分娩前刺激子宫收缩,目的是实现阴道分娩。它指的是各种原因,包括足月妊娠,胎膜早破(PROM),产妇医疗条件和胎儿生长受限。本研究旨在评估引产的患病率,其适应症,以及相关的孕产妇和胎儿的结局在埃塞俄比亚。利用谷歌Scholar、Cochrane、PubMed、HINARI、Web of Science、African Online和埃塞俄比亚大学的机构知识库等广泛认可的数据库对相关文章进行了全面搜索。数据采用乔安娜布里格斯研究所提供的标准格式提取。采用Cochran Q检验和I2统计来评估研究的异质性。采用漏斗图和Egger检验评价发表偏倚。一个森林图被用来表示埃塞俄比亚引产的综合流行率。该系统回顾和荟萃分析显示,埃塞俄比亚引产的总总患病率为14.4% (95% CI: 11.09-17.70; I2 = 95.7%, P
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引用次数: 0
Balancing Scientific and Commercial Interests: The European Health Data Space Response to Commercial Scientific Research. 平衡科学和商业利益:欧洲卫生数据空间对商业科学研究的响应。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-01 Epub Date: 2026-02-21 DOI: 10.1177/00469580261420714
Xuxin Yao, Zheyuan Sun, Hongjie Man

Commercial interests have increasingly engaged in scientific research, particularly as the European Health Data Space (EHDS) allows access to electronic health records for such studies. Normative legal research was conducted to examine EU Member States' effective medical research legislation and landmark cases. Eleven EU Member States' legislation do not reference commercial medical research. Regarding the others, some adopt stricter rules for commercial research. Others prioritize incentives for non-commercial research. Related legislation primarily regulates research based on funding sources, diverging from the multi-actor and multi-interest nature of health data research. Both the GDPR and ethical guidelines generally exempt anonymized data from oversight, creating a governance gap. Low marginal costs and the black-box nature of data-driven approaches further intensify funding biases, potentially undermining public trust. Member States also differ in data subjects' right to opt out of scientific research. Such regulatory fragmentation undermines EHDS implementation and creates opportunities for regulatory arbitrage. Commercial scientific research should be understood as a type of research conducted by profit-driven actors through ongoing business operations. Special measures should be applied to commercial scientific research within the EHDS, including mandatory consideration reflecting data market pricing, tiered data dividends, compulsory health data access body ethical review, conflicts of interest declaration, and opt-out rights for data subjects. Rules for providing data access are tailored to the stage of research and require a balancing test between research interests and trade secrets. Raw data should be made accessible. Processed data should be made available when classified as essential. Research results should always be provided. A centralized EU platform is recommended to reduce administrative burdens.

商业利益越来越多地参与科学研究,特别是因为欧洲卫生数据空间(EHDS)允许获取此类研究的电子健康记录。进行了规范性法律研究,以审查欧盟成员国有效的医学研究立法和具有里程碑意义的案例。11个欧盟成员国的立法不涉及商业性医学研究。至于其他方面,一些国家对商业研究采取了更严格的规定。其他国家则优先考虑非商业研究的激励措施。相关立法主要对基于资金来源的研究进行监管,这偏离了卫生数据研究的多行为者和多利益性质。GDPR和道德准则通常都免除了对匿名数据的监督,这造成了治理空白。低边际成本和数据驱动方法的黑箱性质进一步加剧了资金偏见,可能损害公众的信任。成员国在数据主体选择退出科学研究的权利方面也存在差异。这种监管碎片化破坏了EHDS的实施,并创造了监管套利的机会。商业性科学研究应被理解为由利润驱动的行为者通过持续的商业运作进行的一种研究。在EHDS范围内,商业科学研究应采取特别措施,包括强制性考虑反映数据市场定价、分层数据红利、强制性健康数据访问机构伦理审查、利益冲突声明和数据主体的选择退出权。提供数据访问的规则是根据研究阶段量身定制的,需要在研究兴趣和商业秘密之间进行平衡测试。原始数据应便于查阅。处理后的数据应在分类为必要时提供。应始终提供研究结果。建议建立一个集中的欧盟平台,以减轻行政负担。
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Inquiry-The Journal of Health Care Organization Provision and Financing
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