Pub Date : 2025-01-01Epub Date: 2025-12-01DOI: 10.1177/00469580251398371
Sangita Shakya, Nur Akmar Taha, Shiba Bahadur Karkee, Pathiyil Ravi Shankar
In Nepal, community pharmacies serve as the primary source of medical care. The aim of the current study was to evaluate the effect of an educational intervention on knowledge and practice of dispensing, prescription handling and patient counseling among community pharmacists working in 3 districts (Kathmandu, Lalitpur and Bhaktapur) of Nepal. A quasi-experimental pre-post interventional study was conducted in 123 community pharmacies located in Kathmandu, Bhaktapur, and Lalitpur districts of Nepal. The research questionnaire was developed according to national and international good pharmacy practice guidelines. A structured questionnaire with mainly closed-ended and a few open-ended questions, exploring the knowledge and practice of community pharmacists in the 3 areas mentioned previously was prepared. Demographic information was also collected. The pre-tested questionnaires were completed by the community pharmacy in charge from the selected pharmacy. This data was considered as the pre-intervention data. Education sessions on good pharmacy practice were provided to all selected community pharmacists by expert pharmacists. Three weeks following the educational intervention, post-intervention data was collected at the same pharmacies. The percentage of pharmacies chosen were Kathmandu (48.8%), Lalitpur (30.9%), and Bhaktapur (20.3%). Seventy-four percent of respondents were Diploma in Pharmacy, 21.1% were bachelor's in pharmacy. The major problems faced by the pharmacists during dispensing were inadequate instructions (30.1%), followed by missing duration of therapy (24.4%) and unavailable drugs (22.0%). Other problems included dosage form errors (15.4%), illegible prescriptions (13.0%), dosing errors (13.0%), and drug interactions (13.0%). The educational intervention had a positive impact on both knowledge and practice scores among pharmacists, irrespective of their qualification level. The intervention also significantly improved pharmacists' knowledge and practice scores regardless of gender. The educational intervention improved both knowledge and practice scores in counseling, prescription handling and dispensing. Similar studies in other districts and provinces are required.
{"title":"An Educational Intervention to Strengthen Community Pharmacy Practice in Nepal.","authors":"Sangita Shakya, Nur Akmar Taha, Shiba Bahadur Karkee, Pathiyil Ravi Shankar","doi":"10.1177/00469580251398371","DOIUrl":"10.1177/00469580251398371","url":null,"abstract":"<p><p>In Nepal, community pharmacies serve as the primary source of medical care. The aim of the current study was to evaluate the effect of an educational intervention on knowledge and practice of dispensing, prescription handling and patient counseling among community pharmacists working in 3 districts (Kathmandu, Lalitpur and Bhaktapur) of Nepal. A quasi-experimental pre-post interventional study was conducted in 123 community pharmacies located in Kathmandu, Bhaktapur, and Lalitpur districts of Nepal. The research questionnaire was developed according to national and international good pharmacy practice guidelines. A structured questionnaire with mainly closed-ended and a few open-ended questions, exploring the knowledge and practice of community pharmacists in the 3 areas mentioned previously was prepared. Demographic information was also collected. The pre-tested questionnaires were completed by the community pharmacy in charge from the selected pharmacy. This data was considered as the pre-intervention data. Education sessions on good pharmacy practice were provided to all selected community pharmacists by expert pharmacists. Three weeks following the educational intervention, post-intervention data was collected at the same pharmacies. The percentage of pharmacies chosen were Kathmandu (48.8%), Lalitpur (30.9%), and Bhaktapur (20.3%). Seventy-four percent of respondents were Diploma in Pharmacy, 21.1% were bachelor's in pharmacy. The major problems faced by the pharmacists during dispensing were inadequate instructions (30.1%), followed by missing duration of therapy (24.4%) and unavailable drugs <b>(</b>22.0%). Other problems included dosage form errors (15.4%), illegible prescriptions (13.0%), dosing errors (13.0%), and drug interactions (13.0%). The educational intervention had a positive impact on both knowledge and practice scores among pharmacists, irrespective of their qualification level. The intervention also significantly improved pharmacists' knowledge and practice scores regardless of gender. The educational intervention improved both knowledge and practice scores in counseling, prescription handling and dispensing. Similar studies in other districts and provinces are required.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251398371"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145656127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-12-05DOI: 10.1177/00469580251399372
Ailifeila Akepaer
Although the association between Health Literacy and Mental Health has been explored in previous research, their interplay within digital technology contexts-especially among the aged-remains insufficiently studied. This study aims to explore the association between ICTs usage and the Mental Health of older adults in China and examine the moderating role of Health Literacy in this relationship. This study is a secondary data analysis based on a cross-sectional survey: 2021 Psychological and Behavioral Investigation of Chinese Residents. Descriptive statistical analysis and hierarchical multiple regression analysis were applied. In zero-order correlation analyses, the relationship between ICTs usage and Mental Health was not significant. After controlling for Health Literacy, ICTs usage had a significant negative association with Mental Health (B = -0.129, β = -.16, P < .001). Health Literacy had a positive relationship with Mental Health (B = 0.027, β = .243, P < .001). Further moderation effect analysis showed that introducing the interaction term did not increase the model's explanatory power (ΔR² = .000). Although no moderating effect was found between ICTs usage and Mental Health, Health Literacy may act as a suppressor variable to offset the negative impact of digital technology. Future Mental Health management for the aged should focus on reducing harmful ICTs usage and enhancing Health Literacy levels.
尽管健康素养和心理健康之间的关系在以前的研究中已经被探讨过,但它们在数字技术背景下的相互作用——尤其是在老年人中——仍然没有得到充分的研究。本研究旨在探讨中国老年人信息通信技术使用与心理健康之间的关系,并检验健康素养在这一关系中的调节作用。本研究是基于《2021年中国居民心理与行为调查》横断面调查的二次数据分析。采用描述性统计分析和层次多元回归分析。在零阶相关分析中,信息通信技术使用与心理健康之间的关系不显著。在控制健康素养后,信息通信技术使用与心理健康呈显著负相关(B = -0.129, β = - 0.16, P B = 0.027, β =。243, p r²= .000)。虽然信息通信技术使用与心理健康之间没有发现调节作用,但健康素养可能作为抑制变量来抵消数字技术的负面影响。未来的老年人心理健康管理应侧重于减少有害的信息通信技术使用和提高健康素养水平。
{"title":"Health Literacy Suppresses the Negative Association Between ICTs Usage and Mental Health Among the Aged: A Cross-Sectional Survey.","authors":"Ailifeila Akepaer","doi":"10.1177/00469580251399372","DOIUrl":"10.1177/00469580251399372","url":null,"abstract":"<p><p>Although the association between Health Literacy and Mental Health has been explored in previous research, their interplay within digital technology contexts-especially among the aged-remains insufficiently studied. This study aims to explore the association between ICTs usage and the Mental Health of older adults in China and examine the moderating role of Health Literacy in this relationship. This study is a secondary data analysis based on a cross-sectional survey: 2021 Psychological and Behavioral Investigation of Chinese Residents. Descriptive statistical analysis and hierarchical multiple regression analysis were applied. In zero-order correlation analyses, the relationship between ICTs usage and Mental Health was not significant. After controlling for Health Literacy, ICTs usage had a significant negative association with Mental Health (<i>B</i> = -0.129, β = -.16, <i>P</i> < .001). Health Literacy had a positive relationship with Mental Health (<i>B</i> = 0.027, β = .243, <i>P</i> < .001). Further moderation effect analysis showed that introducing the interaction term did not increase the model's explanatory power (Δ<i>R</i>² = .000). Although no moderating effect was found between ICTs usage and Mental Health, Health Literacy may act as a suppressor variable to offset the negative impact of digital technology. Future Mental Health management for the aged should focus on reducing harmful ICTs usage and enhancing Health Literacy levels.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251399372"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-12-17DOI: 10.1177/00469580251399106
Jingru Han, Yang Zhao, Simeng Gao, Yan Zhang, Yida Wang, Jianfu Zhao
Drug use has emerged as a significant global health concern, contributing to the burden of liver diseases, particularly hepatocellular carcinoma (HCC) and cirrhosis. This study aims to assess the global burden of drug use-related HCC and cirrhosis from 1990 to 2021, using data from the Global Burden of Disease (GBD) study, and to predict future trends up to 2045. Data on drug use-related cirrhosis and HCC were collected from the GBD 2021 database. Joinpoint regression analysis to evaluate temporal trends. Health inequalities were assessed via the slope index of inequality (SII) and the concentration index (CI). Future burden was projected via Bayesian Age-Period-Cohort (BAPC) models. From 1990 to 2021, global mortality and disability-adjusted life-years (DALYs) attributable to drug use-related HCC and cirrhosis increased gradually. The age-standardized death rate (ASDR) for drug use-related HCC increased by 1.96%, whereas the age-standardized DALY rate for HCC increased, with an average annual percentage change (AAPC) of 1.36%. In contrast, the DALY rate for drug use-related cirrhosis declined annually by -0.12%. High socio-demographic index (SDI) regions, particularly high-income North America, presented the highest burden of drug use-related HCC and cirrhosis. The burden of cirrhosis attributable to drug use increased in low-middle-SDI regions. The global burden of liver cancer due to drug use has become more concentrated in high-SDI regions. Future projections indicate that deaths from drug use-related HCC and cirrhosis will continue to increase, with HCC deaths expected to increase by 150.15% and cirrhosis deaths increasing by 43.03% by 2045. The burden of drug use-related cirrhosis and HCC has increased and is projected to continue increasing. This trend highlights the urgent need for targeted public health interventions, improved access to healthcare, and effective drug use prevention strategies, particularly in high-SDI regions.
{"title":"Global Contribution of Drug Use to Cirrhosis and Hepatocellular Carcinoma Worldwide From 1990 to 2021 and Projections to 2045.","authors":"Jingru Han, Yang Zhao, Simeng Gao, Yan Zhang, Yida Wang, Jianfu Zhao","doi":"10.1177/00469580251399106","DOIUrl":"10.1177/00469580251399106","url":null,"abstract":"<p><p>Drug use has emerged as a significant global health concern, contributing to the burden of liver diseases, particularly hepatocellular carcinoma (HCC) and cirrhosis. This study aims to assess the global burden of drug use-related HCC and cirrhosis from 1990 to 2021, using data from the Global Burden of Disease (GBD) study, and to predict future trends up to 2045. Data on drug use-related cirrhosis and HCC were collected from the GBD 2021 database. Joinpoint regression analysis to evaluate temporal trends. Health inequalities were assessed via the slope index of inequality (SII) and the concentration index (CI). Future burden was projected via Bayesian Age-Period-Cohort (BAPC) models. From 1990 to 2021, global mortality and disability-adjusted life-years (DALYs) attributable to drug use-related HCC and cirrhosis increased gradually. The age-standardized death rate (ASDR) for drug use-related HCC increased by 1.96%, whereas the age-standardized DALY rate for HCC increased, with an average annual percentage change (AAPC) of 1.36%. In contrast, the DALY rate for drug use-related cirrhosis declined annually by -0.12%. High socio-demographic index (SDI) regions, particularly high-income North America, presented the highest burden of drug use-related HCC and cirrhosis. The burden of cirrhosis attributable to drug use increased in low-middle-SDI regions. The global burden of liver cancer due to drug use has become more concentrated in high-SDI regions. Future projections indicate that deaths from drug use-related HCC and cirrhosis will continue to increase, with HCC deaths expected to increase by 150.15% and cirrhosis deaths increasing by 43.03% by 2045. The burden of drug use-related cirrhosis and HCC has increased and is projected to continue increasing. This trend highlights the urgent need for targeted public health interventions, improved access to healthcare, and effective drug use prevention strategies, particularly in high-SDI regions.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251399106"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12712323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food advertising may influence food preferences and consumption. Due to these advertisements' role in health, the present study has updated the data available on television and radio food advertisements in Iran until 2020. Meanwhile, food advertisements on billboards have been analyzed for the first time. All programs broadcast on two TV and radio channels were downloaded and saved 24 h daily for one week (November 10-16th, 2020). Also, on November 15th billboards located on the busy highways of Tehran were photographed. Validated protocols analyzed the advertisements. A total of 6026 advertisements were analyzed, including 4287 on TV, 1545 on radio, and 194 on billboards. The total duration of TV and radio advertising was 48.6 h. Food products were the most displayed advertisements on TV, radio, and billboards (33.6%). Overall, "condiments" and "desserts" were the most frequently advertised food products among all the studied media (20% and 17%, respectively). The most common advertising appeal included "High quality" on TV and billboards and "Stimulation of profiteering and profit-seeking" on the radio. Advertising violation based on Iran's regulations, Nutrient profile model for the marketing of food and non-alcoholic beverages to children in the WHO Eastern Mediterranean Region, and International Network for Food and Obesity / Non-communicable Diseases (NCDs) Research Monitoring and Action Support (INFORMAS) was reported to be 13%, 74%, and 51%, respectively. Food products ranked the highest among all the advertisements. A clear violation of domestic and international advertising regulations was observed which given the high share of food advertising in the studied media, could endanger public health. This study supports the need for stricter regulations and adherence to international standards to improve nutritional status.
{"title":"Content Analysis of Food and Beverage Advertisements on TV, Radio, and Billboards in Iran.","authors":"Maryam Amini, Delaram Ghodsi, Mehrnoosh Shafaatdoost, Mohadese Borazjani, Maryam Aghayan, Nastaran Shariatzadeh","doi":"10.1177/00469580251314775","DOIUrl":"10.1177/00469580251314775","url":null,"abstract":"<p><p>Food advertising may influence food preferences and consumption. Due to these advertisements' role in health, the present study has updated the data available on television and radio food advertisements in Iran until 2020. Meanwhile, food advertisements on billboards have been analyzed for the first time. All programs broadcast on two TV and radio channels were downloaded and saved 24 h daily for one week (November 10-16th, 2020). Also, on November 15th billboards located on the busy highways of Tehran were photographed. Validated protocols analyzed the advertisements. A total of 6026 advertisements were analyzed, including 4287 on TV, 1545 on radio, and 194 on billboards. The total duration of TV and radio advertising was 48.6 h. Food products were the most displayed advertisements on TV, radio, and billboards (33.6%). Overall, \"condiments\" and \"desserts\" were the most frequently advertised food products among all the studied media (20% and 17%, respectively). The most common advertising appeal included \"High quality\" on TV and billboards and \"Stimulation of profiteering and profit-seeking\" on the radio. Advertising violation based on Iran's regulations, Nutrient profile model for the marketing of food and non-alcoholic beverages to children in the WHO Eastern Mediterranean Region, and International Network for Food and Obesity / Non-communicable Diseases (NCDs) Research Monitoring and Action Support (INFORMAS) was reported to be 13%, 74%, and 51%, respectively. Food products ranked the highest among all the advertisements. A clear violation of domestic and international advertising regulations was observed which given the high share of food advertising in the studied media, could endanger public health. This study supports the need for stricter regulations and adherence to international standards to improve nutritional status.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251314775"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-08-27DOI: 10.1177/00469580251366975
Daniel P Kessler, William Wygal
We investigate whether the membership of a non-profit hospital's CEO on its board of directors is associated with CEO pay and several measures of hospital performance, including price, operating margin, quality, and service to low-income patients. Although the consequences of CEO board membership for for-profit firms have been studied extensively, the consequences for non-profits in general, and non-profit hospitals in particular, have received less attention. Because most hospitals are non-profit and non-profit hospital prices have increased rapidly over the past 20 years, this gap is important. We use regression models to estimate the association between various measures of hospital performance and CEO board membership, holding constant fixed effects denoting the hospital's county of location, hospital board size, and other hospital characteristics. We find a strong positive association between CEO board membership and non-profit hospital prices, operating margins, and CEO pay, with a weaker positive (negative) association between CEO board membership and quality (service to low-income patients). We conclude that non-profit hospitals' CEO board membership is likely associated with increases in agency costs due to a lack of separation between management and control.
{"title":"Non-Profit Hospital Governance, Conduct, and CEO Pay.","authors":"Daniel P Kessler, William Wygal","doi":"10.1177/00469580251366975","DOIUrl":"https://doi.org/10.1177/00469580251366975","url":null,"abstract":"<p><p>We investigate whether the membership of a non-profit hospital's CEO on its board of directors is associated with CEO pay and several measures of hospital performance, including price, operating margin, quality, and service to low-income patients. Although the consequences of CEO board membership for for-profit firms have been studied extensively, the consequences for non-profits in general, and non-profit hospitals in particular, have received less attention. Because most hospitals are non-profit and non-profit hospital prices have increased rapidly over the past 20 years, this gap is important. We use regression models to estimate the association between various measures of hospital performance and CEO board membership, holding constant fixed effects denoting the hospital's county of location, hospital board size, and other hospital characteristics. We find a strong positive association between CEO board membership and non-profit hospital prices, operating margins, and CEO pay, with a weaker positive (negative) association between CEO board membership and quality (service to low-income patients). We conclude that non-profit hospitals' CEO board membership is likely associated with increases in agency costs due to a lack of separation between management and control.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251366975"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12391706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-08-21DOI: 10.1177/00469580251366150
Vishal Farid Raza, Ayesha Ehsan, Amina Iqbal Khan
Axillary surgery in breast cancer has evolved from radical dissections to selective de-escalations. Identifying patients who may safely omit sentinel lymph node biopsy (SLNB) can further reduce the surgical burden, post operative complications and financial toxicity associated with breast cancer surgical care. The MD Anderson "Nomogram To Predict Positive Sentinel Lymph Nodes After Neoadjuvant Chemotherapy" is widely available and free of charge to assess SLNB positivity post neoadjuvant chemotherapy (NACT). This study externally validates its accuracy in a sample of Pakistani women and assesses its implications for cost effective breast cancer care in a resource limited setting. Retrospective chart review of 150 women who underwent axillary sentinel lymph node biopsy post NACT at Shaukat Khanum Memorial Cancer Hospital from January 2023 to August 2024. Predicted node probability and observed positivity on histopathology were recorded. Calibration (Hosmer-Lemeshow test) and discrimination (C-index) were calculated. 98% were ductal carcinomas; tumor sub-types showed luminal A (42.7%), luminal B (4.7%), her2neu (H2N) enriched (14%) and triple negative (TNBC; 38.7%). 18% (n = 27) nodes were positive on final pathology closely aligning with the nomogram's predicted probability of 17.1 ± 10.3%. Calibration showed good model fit (P = .89) while C-index (0.64) indicated moderate discrimination. 12.6% of women would avoid costs of SLNB if omitted in the 0% to 5% bracket and 31.3% of women in the 0% to 10% bracket. TNBC demonstrated lowest positivity of 6.89% (P = .01). The MD Anderson Clinical Calculator for predicting positive sentinel lymph nodes post NACT may have a role in tailoring decisions for axillary de-escalation especially in patients with a low probability score between 0% and 10% with decrease in costs of breast cancer care in LMICs. Future studies incorporating safety of axillary surgery omission using the calculator and its economic impact are warranted.
乳腺癌的腋窝手术已经从根治性切除发展到选择性降级。确定可以安全省略前哨淋巴结活检(SLNB)的患者可以进一步减少手术负担、术后并发症和与乳腺癌手术护理相关的经济毒性。MD安德森“预测新辅助化疗后前哨淋巴结阳性的Nomogram To Predict新辅助化疗后前哨淋巴结阳性”是一种广泛可用且免费的评估新辅助化疗后SLNB阳性的方法。本研究从外部验证了其在巴基斯坦妇女样本中的准确性,并评估了其在资源有限的情况下对具有成本效益的乳腺癌护理的影响。2023年1月至2024年8月在Shaukat Khanum纪念肿瘤医院接受NACT术后腋窝前哨淋巴结活检的150名妇女的回顾性图表回顾。记录预测结概率和组织病理学观察阳性。计算校正(Hosmer-Lemeshow检验)和判别(c指数)。98%为导管癌;肿瘤亚型表现为luminal A(42.7%)、luminal B(4.7%)、her2neu (H2N)富集(14%)和三阴性(TNBC; 38.7%)。18% (n = 27)淋巴结最终病理呈阳性,与nomogram预测概率(17.1±10.3%)密切相关。校正显示模型拟合良好(P = 0.89), c -指数(0.64)显示中度判别。12.6%的女性会避免SLNB的成本,如果省略在0%至5%的范围内,31.3%的女性在0%至10%的范围内。TNBC阳性率最低,为6.89% (P = 0.01)。用于预测NACT后前哨淋巴结阳性的MD安德森临床计算器可能在腋窝降级的定制决策中发挥作用,特别是在低概率评分为0%至10%的患者中,低收入国家乳腺癌护理成本降低。未来的研究包括使用计算器遗漏腋窝手术的安全性及其经济影响是有必要的。
{"title":"Bridging Global Disparities in Breast Cancer Care: External Validation Study of the MD Anderson \"Nomogram To Predict Positive Sentinel Lymph Nodes After Neoadjuvant Chemotherapy\" and Its Financial Implications of Axillary De-escalation in a Resource Limited Setting.","authors":"Vishal Farid Raza, Ayesha Ehsan, Amina Iqbal Khan","doi":"10.1177/00469580251366150","DOIUrl":"https://doi.org/10.1177/00469580251366150","url":null,"abstract":"<p><p>Axillary surgery in breast cancer has evolved from radical dissections to selective de-escalations. Identifying patients who may safely omit sentinel lymph node biopsy (SLNB) can further reduce the surgical burden, post operative complications and financial toxicity associated with breast cancer surgical care. The MD Anderson \"Nomogram To Predict Positive Sentinel Lymph Nodes After Neoadjuvant Chemotherapy\" is widely available and free of charge to assess SLNB positivity post neoadjuvant chemotherapy (NACT). This study externally validates its accuracy in a sample of Pakistani women and assesses its implications for cost effective breast cancer care in a resource limited setting. Retrospective chart review of 150 women who underwent axillary sentinel lymph node biopsy post NACT at Shaukat Khanum Memorial Cancer Hospital from January 2023 to August 2024. Predicted node probability and observed positivity on histopathology were recorded. Calibration (Hosmer-Lemeshow test) and discrimination (C-index) were calculated. 98% were ductal carcinomas; tumor sub-types showed luminal A (42.7%), luminal B (4.7%), her2neu (H2N) enriched (14%) and triple negative (TNBC; 38.7%). 18% (n = 27) nodes were positive on final pathology closely aligning with the nomogram's predicted probability of 17.1 ± 10.3%. Calibration showed good model fit (<i>P</i> = .89) while C-index (0.64) indicated moderate discrimination. 12.6% of women would avoid costs of SLNB if omitted in the 0% to 5% bracket and 31.3% of women in the 0% to 10% bracket. TNBC demonstrated lowest positivity of 6.89% (<i>P</i> = .01). The MD Anderson Clinical Calculator for predicting positive sentinel lymph nodes post NACT may have a role in tailoring decisions for axillary de-escalation especially in patients with a low probability score between 0% and 10% with decrease in costs of breast cancer care in LMICs. Future studies incorporating safety of axillary surgery omission using the calculator and its economic impact are warranted.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251366150"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-09-03DOI: 10.1177/00469580251366958
Uchechukwu Levi Osuagwu, Robyn Vines
Australians living in rural communities are more likely to experience Domestic violence (DV) than those living in urban areas. Service providers (SP) who provide support to victims of DV in these rural settings encounter some structural barriers at a systems and organizational level that may be useful in improving outreach services. However, few studies have explored SP perspectives surrounding these issues. This study aimed to explore service providers' perspectives on delivering support for DV victims in rural New South Wales (NSW), Australia. This qualitative study utilized structured interviews that were audio recorded and evaluated, using inductive thematic analysis. Ten people from the Central West region of NSW, providing support across DV services, legal services, community centers, medical centers, and the police, were interviewed. Half of the interviewees held roles in organizations that provided DV-specific services. Some service providers noted clients presented with other issues first, before disclosing their experiences with DV. Interviewees described key obstacles, including cultural attitudes, comorbid mental health and substance use disorders, and logistical impediments to leaving relationships and accessing services as barriers for victims. They identified the personal toll of their work and a lack of funding for specialized and multidisciplinary services as challenges to providing effective service delivery. Facilitators such as building trust through community services, using technology for remote support, and community support groups were effective. SP cited DV education in schools as an important avenue for primary prevention. This study highlights the significant barriers and facilitators identified by rural DV service providers in the Central West region of NSW, Australia. Despite the personal toll on providers, supportive networks helped mitigate burnout. The study advocates for increased funding, coordinated multidisciplinary services, and educational programs to address structural and cultural issues in rural DV service delivery at both the systems and organizational levels.
{"title":"Service Providers' Perspectives on Delivering Support for Domestic Violence Victims in Rural New South Wales.","authors":"Uchechukwu Levi Osuagwu, Robyn Vines","doi":"10.1177/00469580251366958","DOIUrl":"10.1177/00469580251366958","url":null,"abstract":"<p><p>Australians living in rural communities are more likely to experience Domestic violence (DV) than those living in urban areas. Service providers (SP) who provide support to victims of DV in these rural settings encounter some structural barriers at a systems and organizational level that may be useful in improving outreach services. However, few studies have explored SP perspectives surrounding these issues. This study aimed to explore service providers' perspectives on delivering support for DV victims in rural New South Wales (NSW), Australia. This qualitative study utilized structured interviews that were audio recorded and evaluated, using inductive thematic analysis. Ten people from the Central West region of NSW, providing support across DV services, legal services, community centers, medical centers, and the police, were interviewed. Half of the interviewees held roles in organizations that provided DV-specific services. Some service providers noted clients presented with other issues first, before disclosing their experiences with DV. Interviewees described key obstacles, including cultural attitudes, comorbid mental health and substance use disorders, and logistical impediments to leaving relationships and accessing services as barriers for victims. They identified the personal toll of their work and a lack of funding for specialized and multidisciplinary services as challenges to providing effective service delivery. Facilitators such as building trust through community services, using technology for remote support, and community support groups were effective. SP cited DV education in schools as an important avenue for primary prevention. This study highlights the significant barriers and facilitators identified by rural DV service providers in the Central West region of NSW, Australia. Despite the personal toll on providers, supportive networks helped mitigate burnout. The study advocates for increased funding, coordinated multidisciplinary services, and educational programs to address structural and cultural issues in rural DV service delivery at both the systems and organizational levels.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251366958"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-09-09DOI: 10.1177/00469580251366142
Charles Ransford, Monique Williams, Gary Slutkin
The Cure Violence approach applies public health epidemic control strategies to reduce violence in highly impacted communities and countries. This paper conducts a systematic review to identify studies analyzing the effectiveness of the Cure Violence approach and provides an overview of their findings. A protocol was developed using the PRISMA guidelines. For this study, we examined findings related only to shootings and killings because these are the outcomes to which the Cure Violence approach is applied. We utilized PubMed database, Google Scholar, and the Cure Violence Global organizational files to look for relevant studies. The review identified 13 papers analyzing 27 program sites and offering 83 findings on the impact of the approach on either shootings or killings. Overall, 68.7% of the findings indicated a reduction in shootings or killings, with 32.5% demonstrating statistically significant decreases. Findings varied geographically, with Baltimore accounting for the highest proportion of sites reporting either an increase in shootings or killings or non-significant results. Outside of Baltimore, 95.8% of sites demonstrated reductions in violence, with 54.2% achieving statistical significance. Notable findings include a 52% reduction in killings in Chicago, a 63% reduction in shootings in New York City, and a 74% reduction in killings in Cali, Colombia. The context surrounding the Baltimore findings underscores the importance of contextual factors in determining program effectiveness. Key components influencing program effectiveness include targeting individuals and groups at highest risk, employing credible messengers to reach individuals and groups at highest risk, real-time violence interruption and conflict mediation, sustained case management, structured monitoring systems with rapid response mechanisms, continuous monitoring of impact on shootings and killings, and sufficient, sustained financial investment. Recommendations to researchers are presented regarding the importance of including contextual factors in future research and understanding the importance of their role in guiding communities in improving the effectiveness of violence prevention programs.
{"title":"A Systematic Review on the Effectiveness of the Cure Violence Approach.","authors":"Charles Ransford, Monique Williams, Gary Slutkin","doi":"10.1177/00469580251366142","DOIUrl":"10.1177/00469580251366142","url":null,"abstract":"<p><p>The Cure Violence approach applies public health epidemic control strategies to reduce violence in highly impacted communities and countries. This paper conducts a systematic review to identify studies analyzing the effectiveness of the Cure Violence approach and provides an overview of their findings. A protocol was developed using the PRISMA guidelines. For this study, we examined findings related only to shootings and killings because these are the outcomes to which the Cure Violence approach is applied. We utilized PubMed database, Google Scholar, and the Cure Violence Global organizational files to look for relevant studies. The review identified 13 papers analyzing 27 program sites and offering 83 findings on the impact of the approach on either shootings or killings. Overall, 68.7% of the findings indicated a reduction in shootings or killings, with 32.5% demonstrating statistically significant decreases. Findings varied geographically, with Baltimore accounting for the highest proportion of sites reporting either an increase in shootings or killings or non-significant results. Outside of Baltimore, 95.8% of sites demonstrated reductions in violence, with 54.2% achieving statistical significance. Notable findings include a 52% reduction in killings in Chicago, a 63% reduction in shootings in New York City, and a 74% reduction in killings in Cali, Colombia. The context surrounding the Baltimore findings underscores the importance of contextual factors in determining program effectiveness. Key components influencing program effectiveness include targeting individuals and groups at highest risk, employing credible messengers to reach individuals and groups at highest risk, real-time violence interruption and conflict mediation, sustained case management, structured monitoring systems with rapid response mechanisms, continuous monitoring of impact on shootings and killings, and sufficient, sustained financial investment. Recommendations to researchers are presented regarding the importance of including contextual factors in future research and understanding the importance of their role in guiding communities in improving the effectiveness of violence prevention programs.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251366142"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study examined sociodemographic and health-related determinants of self-reported unmet health service needs to better understand the factors contributing to inequities among adults aged 50 and older during the COVID-19 pandemic in Latvia. Data from the longitudinal SHARE study-Corona Surveys 1 and 2, and Wave 8-were analysed using logistic regression. A total of 647 cases from Latvia (62.9% women) were included, with a mean age of 68.6 years (±9.6). During the pandemic, 29.5% of adults aged 50 and older encountered barriers to accessing healthcare services. Gender-stratified analysis revealed that older adults from urban areas, men with higher education, and women with chronic conditions and activity limitations were at significantly higher risk of experiencing unmet health service needs. The study reveals significant disparities in health service needs among older adults in Latvia during the COVID-19 pandemic, emphasising the need for targeted interventions to reduce inequalities and improve access for vulnerable populations in public health crises.
{"title":"Inequities in Health Service Needs Among Older Adults During COVID-19: A Gender-Stratified Analysis Using Longitudinal SHARE Data.","authors":"Aija Bukova-Žideļūna, Anda Ķīvīte-Urtāne, Lauma Sprinģe, Ilze Priedīte, Diāna Baltmane, Šime Smolič","doi":"10.1177/00469580251371425","DOIUrl":"10.1177/00469580251371425","url":null,"abstract":"<p><p>This study examined sociodemographic and health-related determinants of self-reported unmet health service needs to better understand the factors contributing to inequities among adults aged 50 and older during the COVID-19 pandemic in Latvia. Data from the longitudinal SHARE study-Corona Surveys 1 and 2, and Wave 8-were analysed using logistic regression. A total of 647 cases from Latvia (62.9% women) were included, with a mean age of 68.6 years (±9.6). During the pandemic, 29.5% of adults aged 50 and older encountered barriers to accessing healthcare services. Gender-stratified analysis revealed that older adults from urban areas, men with higher education, and women with chronic conditions and activity limitations were at significantly higher risk of experiencing unmet health service needs. The study reveals significant disparities in health service needs among older adults in Latvia during the COVID-19 pandemic, emphasising the need for targeted interventions to reduce inequalities and improve access for vulnerable populations in public health crises.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251371425"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-09-11DOI: 10.1177/00469580251365460
Kayla Gardner, Benjamin Ivins, Trinity Mathis Peters, Len Novilla, Ali Crandall, Carl L Hanson
Adverse childhood experiences (ACEs) are linked to lasting health and socioeconomic challenges; however, less is known about how primary care providers' own trauma histories impact their provision of trauma-informed care (TIC). This cross-sectional survey study assessed the relationship between primary care providers' personal trauma history (ACE scores), personal reaction to trauma (burnout, compassion fatigue, and vicarious victimization), and TIC practice. A total of 167 primary care providers were recruited between March 2024 and August 2024 and completed a 38-item online survey. Measures included the Trauma Informed Care-Provider Assessment Tool (TIC-PAT), the Professional Quality of Life Scale (ProQLS), the ACEs Study Questionnaire, and demographics. Descriptive statistics and multiple linear regression analysis was conducted. Respondents were an average of 59.73 years old, white (88.89%) and medical doctors (90.48%). Average ACE score of respondents was 1.4 (SD = 1.47). Analysis revealed that providers with higher ACEs scores were significantly more likely to implement TIC (B = 0.11, P = .02). However, no significant association was found between personal reaction to trauma and TIC provision. Findings suggest that primary care providers with personal trauma histories may be more attuned to the effects of trauma, leading to greater TIC implementation. The study highlights the importance of TIC training for all providers-particularly for those with lower ACE scores-while also recognizing that providers with higher ACE scores may benefit from training to manage personal trauma and enhance their clinical practice.
不良童年经历与持久的健康和社会经济挑战有关;然而,关于初级保健提供者自己的创伤史如何影响他们提供创伤知情护理(TIC)的了解较少。本横断面调查研究评估了初级保健提供者的个人创伤史(ACE分数)、个人对创伤的反应(倦怠、同情疲劳和代理受害)和TIC实践之间的关系。在2024年3月至2024年8月期间,共招募了167名初级保健提供者,并完成了一项38项在线调查。测量方法包括创伤知情护理提供者评估工具(TIC-PAT)、职业生活质量量表(ProQLS)、ace研究问卷和人口统计。进行描述性统计和多元线性回归分析。受访者平均年龄59.73岁,白人占88.89%,医生占90.48%。被调查者的ACE平均得分为1.4 (SD = 1.47)。分析显示,ace得分较高的医护人员实施TIC的可能性显著高于其他医护人员(B = 0.11, P = 0.02)。然而,个人对创伤的反应与TIC提供之间没有明显的联系。研究结果表明,有个人创伤史的初级保健提供者可能更适应创伤的影响,从而导致更多的TIC实施。该研究强调了对所有提供者进行TIC培训的重要性,特别是对那些ACE分数较低的提供者,同时也认识到ACE分数较高的提供者可能从培训中受益,以管理个人创伤并提高他们的临床实践。
{"title":"The Influence of Adverse Childhood Experiences on Trauma Informed Care Among Primary Care Providers: A Cross-Sectional Study.","authors":"Kayla Gardner, Benjamin Ivins, Trinity Mathis Peters, Len Novilla, Ali Crandall, Carl L Hanson","doi":"10.1177/00469580251365460","DOIUrl":"10.1177/00469580251365460","url":null,"abstract":"<p><p>Adverse childhood experiences (ACEs) are linked to lasting health and socioeconomic challenges; however, less is known about how primary care providers' own trauma histories impact their provision of trauma-informed care (TIC). This cross-sectional survey study assessed the relationship between primary care providers' personal trauma history (ACE scores), personal reaction to trauma (burnout, compassion fatigue, and vicarious victimization), and TIC practice. A total of 167 primary care providers were recruited between March 2024 and August 2024 and completed a 38-item online survey. Measures included the Trauma Informed Care-Provider Assessment Tool (TIC-PAT), the Professional Quality of Life Scale (ProQLS), the ACEs Study Questionnaire, and demographics. Descriptive statistics and multiple linear regression analysis was conducted. Respondents were an average of 59.73 years old, white (88.89%) and medical doctors (90.48%). Average ACE score of respondents was 1.4 (SD = 1.47). Analysis revealed that providers with higher ACEs scores were significantly more likely to implement TIC (<i>B</i> = 0.11, <i>P</i> = .02). However, no significant association was found between personal reaction to trauma and TIC provision. Findings suggest that primary care providers with personal trauma histories may be more attuned to the effects of trauma, leading to greater TIC implementation. The study highlights the importance of TIC training for all providers-particularly for those with lower ACE scores-while also recognizing that providers with higher ACE scores may benefit from training to manage personal trauma and enhance their clinical practice.</p>","PeriodicalId":54976,"journal":{"name":"Inquiry-The Journal of Health Care Organization Provision and Financing","volume":"62 ","pages":"469580251365460"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12426388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}