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[Rare Compression Syndrome of the Median Nerve due to a Supracondylar Humeral Process and a Ligament of Struthers]. [肱骨髁上突和斯特鲁瑟斯韧带导致的正中神经罕见压迫综合征]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-02-01 Epub Date: 2024-02-15 DOI: 10.1055/a-2234-4636
Davide Tosin, Gregor Antoniadis, Christian Rainer Wirtz, Maria Teresa Pedro

Introduction: A supracondylar process is a bony spur on the distal anteromedial surface of the humerus, and it is considered an anatomical variant with a prevalence of 0.4-2.7% according to anatomical studies. In almost all cases, it is associated with a fibrous, sometimes ossified ligament, which extends from the supracondylar process to the medial epicondyle. This ligament is known in the literature as the ligament of Struthers, named after the Scottish anatomist who first described it in detail in 1854. In rare cases, the supracondylar process can be a clinically relevant finding as a cause of nerve compression syndrome. The median and ulnar nerve can be trapped by the ring-shaped structure formed by the ligament of Struthers and the supracondylar process.

Case report: A 59-year-old patient with symptoms of a cubital tunnel syndrome and additional ipsilateral sensory deficits in his thumb was referred to our clinic. Electroneurography showed no signs of an additional carpal tunnel syndrome. Preoperative x-ray and CT scans of the upper arm revealed a supracondylar process, which led us to suspect an associated entrapment of the median nerve. An MRI scan of the upper arm showed a ligament of Struthers and signs of a related median nerve compression as we initially assumed. We performed a surgical decompression of the median nerve in the distal upper arm and of the ulnar nerve in the cubital tunnel. Intraoperatively, there was evidence of compression of the median nerve due to the supracondylar process and the ligament of Struthers. The latter was cleaved and then resected along with the supracondylar process. Three months after surgery, the patient had no motor or sensory deficits.

Summary: The ring-shaped structure formed by the supracondylar process and ligament of Struthers represents a rare cause of compression syndrome of the median and ulnar nerve. Its incidence remains unknown so far. This anatomical variant should be considered a differential diagnosis in case of possibly related nerve entrapment symptoms after ruling out other, more frequent nerve compression causes. Moreover, the supracondylar process should be completely resected including the periosteum during surgery to minimise the risk of recurrence.

导言肱骨髁上突是肱骨远端前内侧表面的骨刺,根据解剖学研究,它被认为是一种解剖变异,发病率为 0.4-2.7%。几乎所有病例都伴有一条纤维韧带,有时是骨化韧带,从肱骨髁上突延伸到内上髁。这种韧带在文献中被称为 Struthers 韧带,是以 1854 年首次对其进行详细描述的苏格兰解剖学家的名字命名的。在极少数情况下,髁上突可作为神经压迫综合征的临床相关病因。正中神经和尺神经可能被斯特鲁瑟韧带和肱骨髁上突形成的环形结构卡住:一名 59 岁的患者因出现肘隧道综合征症状和同侧拇指感觉障碍而转诊至我院。电神经图显示,患者没有额外的腕管综合征症状。术前上臂的X光和CT扫描显示有髁上突起,这让我们怀疑正中神经有相关的卡压。上臂的核磁共振成像扫描显示了 Struthers 韧带和我们最初推测的正中神经受压迹象。我们对上臂远端正中神经和肘隧道尺神经进行了手术减压。术中发现,正中神经受到肱骨髁上突和 Struthers 韧带的压迫。后者被劈开,然后与肱骨髁上突一起切除。小结:由肱骨髁上突和 Struthers 韧带形成的环形结构是正中神经和尺神经压迫综合征的罕见病因。迄今为止,其发病率仍然未知。在排除其他更常见的神经压迫病因后,如果出现可能相关的神经卡压症状,应将这种解剖变异视为鉴别诊断。此外,手术时应完全切除肱骨髁上突,包括骨膜,以最大限度地降低复发风险。
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引用次数: 0
[Nerve Transfers in Children with Non-traumatic Amyoplasia] Nerventransfers bei Kindern mit nicht traumatischer Amyoplasie非创伤性肌萎缩儿童的神经转移。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-02-01 Epub Date: 2024-03-20 DOI: 10.1055/a-2240-4781
Benedikt Schäfer, Justus P Beier, Jörg Bahm

Background: The treatment of obstetric brachial plexus palsy through primary reconstruction and nerve transfers has been established in the past decades. In the case of non-traumatic diseases that lead to flaccid paralysis and the inability to move the extremities, such as transverse myelitis (TM) or arthrogryposis multiplex congenita (AMC), which can have a wide variety of causes, the focus has been on rehabilitative therapy so far, while surgical interventions have been used to a lesser extent, e. g., in the form of osteotomies or muscle transfers. Our aim is to establish nerve transfers as a surgical option to improve mobility in non-traumatic amyoplasia.

Patients: This work presents the needs-adapted treatment of a total of 23 patients (aged 4 months to 64 months, 18 with AMC and 5 with TM) using nerve transfers on the upper extremity.

Results: We were able to show that early nerve transfers in the upper extremity enabled the reanimation of muscles in both AMC and TM.

Conclusion: This work shows that the treatment of non-traumatic amyoplasia in children with selective nerve grafts is a successful method. Nerve transfers allow patients to gain or regain important functions for managing independent everyday life. The surgical methods have been established in the treatment of traumatic nerve injuries. They are well-known and can be carried out safely. We believe that this is an important treatment option for paediatric patients with paralysis associated with TM or AMC, which should also be known to the treating physicians.

背景:产科臂丛神经瘫痪的原发性重建和神经转移治疗方法在过去几十年中已经确立。对于非创伤性疾病导致的弛缓性瘫痪和肢体活动障碍,如横贯性脊髓炎(TM)或先天性多关节炎(AMC),其病因多种多样,迄今为止,治疗的重点一直是康复治疗,而手术干预的使用程度较低,如截骨或肌肉转移。我们的目标是将神经转移作为一种手术选择,以改善非创伤性肌萎缩症患者的活动能力:本研究介绍了对23名患者(年龄在4个月至64个月之间,其中18人患有AMC,5人患有TM)进行神经转移治疗的结果:结果:我们能够证明,早期上肢神经转移能够使 AMC 和 TM 患者的肌肉恢复活力:结论:这项研究表明,通过选择性神经移植治疗儿童非创伤性肌萎缩症是一种成功的方法。神经移植可使患者获得或恢复重要功能,从而能够独立处理日常生活。治疗创伤性神经损伤的手术方法已经确立。这些方法广为人知,而且可以安全实施。我们认为,这对患有颞下颌关节炎或颞下颌关节综合症相关性瘫痪的儿科患者来说是一种重要的治疗选择,主治医生也应了解这一点。
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引用次数: 0
[Goal-setting in Plastic Surgery using the SMART principle]. [使用SMART原则制定整形外科目标]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2023-12-01 Epub Date: 2023-11-02 DOI: 10.1055/a-2157-0946
Rafael G Jakubietz, Riccardo E Giunta, Michael G Jakubietz, Sarah König

Introduction: The process of continuous acquisition of surgical expertise is a key element in registrar training. The principle of active, self-directed learning, which is regularly applied in medical school, can also be used to gain surgical expertise in registrar training.

Methods: Surgical training can be compared to acquiring expertise in music or sport, where both intellectual and manual capabilities are required. Specific training principles, including analysis, goal setting, practice and reflection on the process, are commonly encountered in these fields. Smart goal setting is preferred in order to ensure compliance and a successful strategy. This can also be used in plastic surgery training.

Application: Surgical principles as well as partial or complete surgical procedures can be practiced using the smart principle. The fragmentation of a larger task into smaller units allows rapid acquisition of surgical expertise without impeding patient safety.

Discussion: Surgical training today happens in a setting caught between economic and medicolegal challenges. The reduction of case load requires simulation practice as well as self-directed learning - which has been shown to improve outcomes. The smart principle allows distinct goal setting which can improve compliance of the student and increase success. As this form of learning is not intuitive to all individuals, supervisors and mentor can support trainees in the acquisition of surgical expertise using this principle.

引言:不断获取外科专业知识的过程是注册医生培训的一个关键要素。医学院经常采用主动、自主学习的原则,也可以用于在注册医生培训中获得外科专业知识。方法:手术训练可以比作获得音乐或体育方面的专业知识,这需要智力和体力。在这些领域中,通常会遇到具体的培训原则,包括分析、目标设定、实践和对过程的反思。明智的目标设定是首选,以确保合规性和成功的战略。这也可以用于整形外科训练。应用:手术原理以及部分或完整的手术程序都可以使用智能原理进行实践。将较大的任务分解为较小的单元,可以在不妨碍患者安全的情况下快速获得外科专业知识。讨论:今天的外科培训是在一个夹在经济和法医挑战之间的环境中进行的。减少案例量需要模拟练习和自主学习,这已被证明可以改善结果。聪明的原则允许设定明确的目标,这可以提高学生的依从性并增加成功率。由于这种学习形式并非对所有人都是直观的,主管和导师可以利用这一原则支持受训人员获得外科专业知识。
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引用次数: 0
[Black clothes make a difference - Physical properties of Black clothes in Burn Injuries caused by solar radiation]. [黑色衣服与众不同--太阳辐射造成烧伤时黑色衣服的物理特性]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2023-12-01 Epub Date: 2023-05-24 DOI: 10.1055/a-1988-1433
Patrick Mandal, Peter Kronberger, Anton H Schwabegger, Christoph Tasch, Gerhard Pierer
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引用次数: 0
[German Translation and Validation of the Patient-Oriented Questionnaire "Thumb Disability Examination" (TDX) for Specific Diagnosis and Follow-Up of Thumb Carpometacarpal Joint Osteoarthritis]. [以患者为导向的 "拇指残疾检查"(TDX)问卷的德文翻译和验证,用于拇指掌腕关节骨关节炎的具体诊断和随访]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2023-12-01 Epub Date: 2023-12-07 DOI: 10.1055/a-2192-9410
Sinan Mert, Iana Emelianova, Nicholas Möllhoff, Moritz Christian Bader, Riccardo Giunta, Elisabeth Maria Haas-Lützenberger

Background: Patient-reported outcome measures (PROMs) are becoming increasingly important in today's patient care. Unfortunately, the most common PROMs in hand surgery are very time-consuming and usually do not cover the actual, diagnosis-specific complaints of the patients. For diagnosis and follow-up of thumb carpometacarpal joint osteoarthritis, Noback et al. developed and validated the Thumb Disability Examination (TDX) questionnaire. This 20-item questionnaire specifically assesses daily living limitations and pain as well as patient-reported satisfaction of thumb function. The aim of this study is to validate the German translation of the TDX, the Thumb Disability Examination - German (TDX-G), and to compare it with the German-language versions of the MHQ and qDASH, which are currently used as gold standard.

Material und methods: Translation and back-translation were performed in accordance with accepted guidelines. For statistical validation of the TDX-G, 30 consecutive patients with thumb carpometacarpal joint osteoarthritis were interviewed under standardised conditions. Internal consistency was calculated using Cronbach's alpha. Test-retest reliability was determined in 10 patients who completed the TDX-G twice at an interval of 2 weeks. The validity of the TDX-G was determined by calculating the correlation coefficients of the TDX-G with the MHQ and qDASH, subjective pain sensation (NRS), and hand strength levels (coarse and pinch strength). In addition, the time to collect each questionnaire was compared.

Results: The TDX-G has high internal consistency (Cronbach's alpha 0.932) and test-retest reliability (intraclass correlation coefficient 0.963 [0.850-0.991]). There is a significant correlation between TDX-G and MHQ (- 0.782; p<0.001) and qDASH (0.833; p<0.001). All questionnaires correlate significantly with pain on exertion and pinch force, with the TDX-G having the highest correlation in each case. Significantly less time is needed to record the TDX-G (110±28 s) than to record the MHQ (413±98 s).

Conclusion: The TDX-G is a reliable tool for diagnosing and monitoring the progression of thumb carpometacarpal joint osteoarthritis. It can be used in both patient care and clinical research and accurately mirrors the symptoms.

背景:患者报告结果测量(PROMs)在当今的患者护理中变得越来越重要。遗憾的是,手外科最常见的 PROM 非常耗时,而且通常不包括患者实际的、特定诊断的主诉。为了诊断和随访拇指腕掌关节骨关节炎,Noback 等人开发并验证了拇指残疾检查 (TDX) 问卷。该问卷共有 20 个项目,专门评估日常生活限制、疼痛以及患者对拇指功能的满意度。本研究的目的是验证 TDX 的德语翻译版本--拇指残疾检查-德语(TDX-G),并将其与目前作为金标准的德语版 MHQ 和 qDASH 进行比较:材料和方法:翻译和回译均按照公认的准则进行。为了对 TDX-G 进行统计验证,在标准化条件下对 30 名连续的拇指腕掌关节骨关节炎患者进行了访谈。采用克朗巴赫α计算内部一致性。10 名患者两次完成了 TDX-G 的测试,每次间隔 2 周。通过计算 TDX-G 与 MHQ 和 qDASH、主观疼痛感觉(NRS)和手部力量水平(粗力和捏力)的相关系数,确定了 TDX-G 的有效性。此外,还对收集每份问卷的时间进行了比较:结果:TDX-G 具有较高的内部一致性(Cronbach's alpha 0.932)和测试-再测可靠性(类内相关系数 0.963 [0.850-0.991])。TDX-G 与 MHQ 之间存在明显的相关性(- 0.782;p 结论:TDX-G 是诊断和监测拇指腕掌关节骨关节炎进展的可靠工具。它可用于患者护理和临床研究,并能准确反映症状。
{"title":"[German Translation and Validation of the Patient-Oriented Questionnaire \"Thumb Disability Examination\" (TDX) for Specific Diagnosis and Follow-Up of Thumb Carpometacarpal Joint Osteoarthritis].","authors":"Sinan Mert, Iana Emelianova, Nicholas Möllhoff, Moritz Christian Bader, Riccardo Giunta, Elisabeth Maria Haas-Lützenberger","doi":"10.1055/a-2192-9410","DOIUrl":"https://doi.org/10.1055/a-2192-9410","url":null,"abstract":"<p><strong>Background: </strong>Patient-reported outcome measures (PROMs) are becoming increasingly important in today's patient care. Unfortunately, the most common PROMs in hand surgery are very time-consuming and usually do not cover the actual, diagnosis-specific complaints of the patients. For diagnosis and follow-up of thumb carpometacarpal joint osteoarthritis, Noback et al. developed and validated the Thumb Disability Examination (TDX) questionnaire. This 20-item questionnaire specifically assesses daily living limitations and pain as well as patient-reported satisfaction of thumb function. The aim of this study is to validate the German translation of the TDX, the Thumb Disability Examination - German (TDX-G), and to compare it with the German-language versions of the MHQ and qDASH, which are currently used as gold standard.</p><p><strong>Material und methods: </strong>Translation and back-translation were performed in accordance with accepted guidelines. For statistical validation of the TDX-G, 30 consecutive patients with thumb carpometacarpal joint osteoarthritis were interviewed under standardised conditions. Internal consistency was calculated using Cronbach's alpha. Test-retest reliability was determined in 10 patients who completed the TDX-G twice at an interval of 2 weeks. The validity of the TDX-G was determined by calculating the correlation coefficients of the TDX-G with the MHQ and qDASH, subjective pain sensation (NRS), and hand strength levels (coarse and pinch strength). In addition, the time to collect each questionnaire was compared.</p><p><strong>Results: </strong>The TDX-G has high internal consistency (Cronbach's alpha 0.932) and test-retest reliability (intraclass correlation coefficient 0.963 [0.850-0.991]). There is a significant correlation between TDX-G and MHQ (- 0.782; p<0.001) and qDASH (0.833; p<0.001). All questionnaires correlate significantly with pain on exertion and pinch force, with the TDX-G having the highest correlation in each case. Significantly less time is needed to record the TDX-G (110±28 s) than to record the MHQ (413±98 s).</p><p><strong>Conclusion: </strong>The TDX-G is a reliable tool for diagnosing and monitoring the progression of thumb carpometacarpal joint osteoarthritis. It can be used in both patient care and clinical research and accurately mirrors the symptoms.</p>","PeriodicalId":55075,"journal":{"name":"Handchirurgie Mikrochirurgie Plastische Chirurgie","volume":"55 6","pages":"443-449"},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138813675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The split turnover pectoralis muscle flap: an easy and safe method for sternal wound coverage]. [分割翻转胸肌瓣:一种简单安全的胸骨伤口覆盖方法]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2023-12-01 Epub Date: 2023-06-27 DOI: 10.1055/a-2060-0814
Claas Spengler, Frank Masberg, Roland Mett

The conventional pectoralis muscle flap is well known for the reconstruction of sternal defects after deep sternal wound infection. The pectoralis muscle flap can be harvested as an advancement flap based on the thoracoacromial artery, or it can be harvested as a turnover flap based on intercostal perforators of the internal thoracic artery. A disadvantage of the advancement flap can be seen in its limited reach, especially for covering the lower third of the sternum. The turnover flap is well suited for coverage of the lower and middle sternal third, but then lacks the length for coverage of the cranial third. The authors describe a new method for splitting up the pectoralis turnover muscle flap along its muscle fibres in order to gain additional length. Between 2017 and 2022, we treated 12 patients with this method. Total wound coverage and closure have been achieved in all 12 patients. Thus, the split turnover pectoralis flap is a safe and effective method for sternal wound treatment.

传统的胸肌瓣在胸骨深部伤口感染后重建胸骨缺损方面广为人知。胸肌瓣可以胸锁乳突动脉为基础,以推进瓣的形式获取,也可以胸内动脉肋间穿孔器为基础,以翻转瓣的形式获取。推进皮瓣的缺点在于其覆盖范围有限,尤其是在覆盖胸骨下三分之一时。翻转皮瓣非常适合覆盖胸骨中下1/3,但缺乏覆盖颅骨1/3的长度。作者描述了一种沿胸肌肌纤维分割胸肌翻转肌皮瓣以获得额外长度的新方法。在 2017 年至 2022 年期间,我们用这种方法治疗了 12 名患者。所有 12 名患者都实现了伤口的完全覆盖和闭合。因此,分割翻转胸肌皮瓣是一种安全有效的胸骨伤口治疗方法。
{"title":"[The split turnover pectoralis muscle flap: an easy and safe method for sternal wound coverage].","authors":"Claas Spengler, Frank Masberg, Roland Mett","doi":"10.1055/a-2060-0814","DOIUrl":"10.1055/a-2060-0814","url":null,"abstract":"<p><p>The conventional pectoralis muscle flap is well known for the reconstruction of sternal defects after deep sternal wound infection. The pectoralis muscle flap can be harvested as an advancement flap based on the thoracoacromial artery, or it can be harvested as a turnover flap based on intercostal perforators of the internal thoracic artery. A disadvantage of the advancement flap can be seen in its limited reach, especially for covering the lower third of the sternum. The turnover flap is well suited for coverage of the lower and middle sternal third, but then lacks the length for coverage of the cranial third. The authors describe a new method for splitting up the pectoralis turnover muscle flap along its muscle fibres in order to gain additional length. Between 2017 and 2022, we treated 12 patients with this method. Total wound coverage and closure have been achieved in all 12 patients. Thus, the split turnover pectoralis flap is a safe and effective method for sternal wound treatment.</p>","PeriodicalId":55075,"journal":{"name":"Handchirurgie Mikrochirurgie Plastische Chirurgie","volume":" ","pages":"437-442"},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9683797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Choice of flaps for phalloplasty: what is the contemporary standard? Consensus Statement of the German-Speaking Society for Microsurgery of Peripheral Nerves and Vessels]. [阴茎成形术皮瓣的选择:当代标准是什么?德语外周神经和血管显微外科学会的共识声明]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2023-12-01 Epub Date: 2023-10-02 DOI: 10.1055/a-2134-5891
Lara Küenzlen, Jens Christian Wallmichrath, Markus V Küntscher, Jens Rothenberger, Christian Laback, Dirk Johannes Schaefer, Jürgen Schaff, Ahmet Bozkurt, Gabriel Djedovic, Stefan Langer, Tobias Hirsch, Ulrich Rieger

The ever-expanding number of transmen as well as their surgeons share an increasing interest in the construction of a neophallus. While the indication for surgery and the positive effect of a phalloplasty on the quality of life, mental health and sexual function has already been thoroughly analysed, there is a lack of data comparing and evaluating the surgical steps. During the consensus conference on the "choice of flaps for phalloplasty" at the annual meeting of the German-Speaking Society for Microsurgery of Peripheral Nerves and Vessels, the current literature was discussed and a consensus on the surgical technique of a phalloplasty was reached. This manuscript publishes jointly developed recommendations on the following topics: choice of flaps for phalloplasty, preoperative diagnostic tests before phalloplasty, urethral construction in the radial forearm flap and anterior lateral thigh flap, preformation of the urethra at the forearm or thigh, venous drainage of the radial forearm flap, innervation of the phallus, staged phalloplasty, coronaplasty and managing the donor site of a radial forearm flap.

越来越多的跨性别者和他们的外科医生对新阴茎的构建越来越感兴趣。虽然手术指征和阴茎成形术对生活质量、心理健康和性功能的积极影响已经得到了彻底的分析,但缺乏比较和评估手术步骤的数据。在德国外周神经和血管显微外科学会年会上关于“阴茎成形术皮瓣的选择”的共识会议上,讨论了当前的文献,并就阴茎成形术的手术技术达成了共识。这份手稿发表了关于以下主题的联合建议:阴茎成形术皮瓣的选择、阴茎成形术前的术前诊断测试、前臂桡侧皮瓣和大腿前外侧皮瓣的尿道结构、前臂或大腿尿道的预成形、前臂桡状皮瓣的静脉引流、阴茎的神经支配、阶段性阴茎成形术,冠状动脉成形术和前臂桡侧皮瓣的供区管理。
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引用次数: 0
[Changes of the Impact Factor 2022]. [影响因子2022的变化]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2023-12-01 Epub Date: 2023-11-15 DOI: 10.1055/a-2023-3845
Riccardo E Giunta
{"title":"[Changes of the Impact Factor 2022].","authors":"Riccardo E Giunta","doi":"10.1055/a-2023-3845","DOIUrl":"10.1055/a-2023-3845","url":null,"abstract":"","PeriodicalId":55075,"journal":{"name":"Handchirurgie Mikrochirurgie Plastische Chirurgie","volume":" ","pages":"408-410"},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[HaMiPla Best Paper Award - Your Favourites in 2022]. [HaMiPla 最佳论文奖--2022 年您的最爱]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2023-12-01 Epub Date: 2023-12-07 DOI: 10.1055/a-2202-6243
Daria Gose, Sonja Schmid
{"title":"[HaMiPla Best Paper Award - Your Favourites in 2022].","authors":"Daria Gose, Sonja Schmid","doi":"10.1055/a-2202-6243","DOIUrl":"https://doi.org/10.1055/a-2202-6243","url":null,"abstract":"","PeriodicalId":55075,"journal":{"name":"Handchirurgie Mikrochirurgie Plastische Chirurgie","volume":"55 6","pages":"470-471"},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138813677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Searching for Evidence: A Systematic Review of the Pathology of Lipoedema]. [寻找证据:脂水肿病理的系统综述]。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2023-12-01 Epub Date: 2023-11-20 DOI: 10.1055/a-2183-7414
Sarah Funke, Constanze Kuhlmann, Sara Taha, Benedikt Fuchs, Paul Severin Wiggenhauser, Riccardo E Giunta

Background: Lipoedema is a symmetrically localised, painful hypertrophy of subcutaneous adipose tissue in the extremities with marked disproportion to the trunk, and almost exclusively affects females. Despite being first described over 80 years ago, the aetiology and pathogenesis of the disease are largely unknown and are currently the subject of intensive research efforts.

Methods: To summarise the current evidence-based literature on the cellular pathologies and aetiology of lipoedema, a PRISMA-based systematic review was conducted within the National Library of Medicine and Cochrane databases.

Results: A total of 53 studies were identified and included in this review. The results were classified and summarised into categories.

Conclusion: Although there has been a significant increase in research activity and recent publication of extensive studies with a histological and molecular genetic focus, the fundamental aetiology and pathology of lipoedema remains largely unclear. The current data shows discrepancies across studies, particularly with regard to the "oedematous" component of lipoedema. The frequently present comorbidities "lymphoedema" and "obesity", primarily in advanced stages of lipoedema, complicate the diagnostic differentiation and clear definition of study cohorts in scientific research.

背景:脂肪水肿是四肢皮下脂肪组织的一种局部对称、疼痛性肥大,与躯干明显不成比例,几乎只发生在女性身上。尽管在80多年前首次被描述,但该病的病因和发病机制在很大程度上是未知的,目前是深入研究的主题。方法:为了总结目前关于脂肪水肿的细胞病理学和病因学的循证文献,我们在美国国家医学图书馆和Cochrane数据库中进行了基于prisma的系统综述。结果:本综述共纳入53项研究。结果被分类和总结成几类。结论:尽管在组织学和分子遗传学方面的研究活动和最近发表的大量研究显著增加,但脂肪水肿的基本病因和病理在很大程度上仍不清楚。目前的数据显示了不同研究之间的差异,特别是关于脂水肿的“水肿”成分。常出现的合并症“淋巴水肿”和“肥胖”,主要发生在脂水肿的晚期,使科学研究中的诊断鉴别和研究队列的明确定义复杂化。
{"title":"[Searching for Evidence: A Systematic Review of the Pathology of Lipoedema].","authors":"Sarah Funke, Constanze Kuhlmann, Sara Taha, Benedikt Fuchs, Paul Severin Wiggenhauser, Riccardo E Giunta","doi":"10.1055/a-2183-7414","DOIUrl":"10.1055/a-2183-7414","url":null,"abstract":"<p><strong>Background: </strong>Lipoedema is a symmetrically localised, painful hypertrophy of subcutaneous adipose tissue in the extremities with marked disproportion to the trunk, and almost exclusively affects females. Despite being first described over 80 years ago, the aetiology and pathogenesis of the disease are largely unknown and are currently the subject of intensive research efforts.</p><p><strong>Methods: </strong>To summarise the current evidence-based literature on the cellular pathologies and aetiology of lipoedema, a PRISMA-based systematic review was conducted within the National Library of Medicine and Cochrane databases.</p><p><strong>Results: </strong>A total of 53 studies were identified and included in this review. The results were classified and summarised into categories.</p><p><strong>Conclusion: </strong>Although there has been a significant increase in research activity and recent publication of extensive studies with a histological and molecular genetic focus, the fundamental aetiology and pathology of lipoedema remains largely unclear. The current data shows discrepancies across studies, particularly with regard to the \"oedematous\" component of lipoedema. The frequently present comorbidities \"lymphoedema\" and \"obesity\", primarily in advanced stages of lipoedema, complicate the diagnostic differentiation and clear definition of study cohorts in scientific research.</p>","PeriodicalId":55075,"journal":{"name":"Handchirurgie Mikrochirurgie Plastische Chirurgie","volume":" ","pages":"411-426"},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138178066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Handchirurgie Mikrochirurgie Plastische Chirurgie
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